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searching for Lipid droplet 91 found (122 total)

BSCL2 (986 words) [view diff] exact match in snippet view article find links to article

Berardinelli-Seip congenital lipodystrophy 2 (seipin), seipin lipid droplet biogenesis associated, BSCL2 lipid droplet biogenesis associated, seipin, HMN5C External IDs

CIDEB (895 words) [view diff] exact match in snippet view article find links to article

oxidation and whole body metabolism. CIDEB plays a key role in determining lipid droplet size: overexpression of CIDEB in vitro results in fat accumulation by

Tobias Walther (594 words) [view diff] exact match in snippet view article find links to article

the rapidly growing field of lipid droplet biology. His group extensively studied proteins required to adjust lipid droplet size and composition according

PTGFRN (687 words) [view diff] exact match in snippet view article find links to article

"Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells". J. Lipid Res. 39 (6): 1152–61. doi:10

Fas associated factor family member 2 (549 words) [view diff] exact match in snippet view article find links to article

ubiquitin-like (UBX)-domain-containing protein Ubx2/Ubxd8 regulates lipid droplet homeostasis". J. Cell Sci. 125 (Pt 12): 2930–9. doi:10.1242/jcs.100230

Hormone-sensitive lipase (1,904 words) [view diff] exact match in snippet view article find links to article

This triggers them to "spread out" and allow for HSL to enter the lipid droplet. Activation of partially purified HSL requires Mg2+, ATP, and cyclic

3T3-L1 (1,907 words) [view diff] exact match in snippet view article find links to article

been widely utilized, since its development, due to its affinity for lipid droplet deposition in vitro. 3T3-L1 cells have a fibroblast-like morphology

Neutral lipid storage disease (1,998 words) [view diff] exact match in snippet view article find links to article

rapidly used by the body, limiting storage and therefore alleviating lipid droplet accumulation. Foods with medium-chain fatty acids include dairy, fat

Adipose triglyceride lipase (1,825 words) [view diff] exact match in snippet view article find links to article

Lin L, Brown WJ, Jackson CL (January 2006). "ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells". EMBO Reports. 7 (1): 106–113

HSD17B13 (326 words) [view diff] exact match in snippet view article find links to article

extracellular region lipid droplet cytosol cellular component Biological process positive regulation of lipid biosynthetic process lipid droplet organization

AUP1 (567 words) [view diff] exact match in snippet view article find links to article

Aliases AUP1, ancient ubiquitous protein 1, lipid droplet regulating VLDL assembly factor, AUP1 lipid droplet regulating VLDL assembly factor External IDs

Christoph Benning (2,964 words) [view diff] exact match in snippet view article find links to article

regulatory factors and enzymes required for triacylglycerol biosynthesis, lipid droplet formation and lipid turnover in the microalgae Chlamydomonas reinhardtii

PNPLA3 (815 words) [view diff] exact match in snippet view article find links to article

integral component of membrane endoplasmic reticulum membrane cytoplasm lipid droplet membrane Biological process lipid catabolic process triglyceride biosynthetic

Chaperone-mediated autophagy (3,623 words) [view diff] exact match in snippet view article find links to article

defective DNA repair. CMA degrades lipid droplet proteins (perilipin 2 and perilipin 3). Removal of these lipid droplet coat proteins by CMA precedes lipolysis

RAB3GAP1 (939 words) [view diff] exact match in snippet view article find links to article

activity protein binding Cellular component cytoplasm Golgi apparatus lipid droplet endoplasmic reticulum tubular network extracellular exosome endoplasmic

CIDEA (744 words) [view diff] exact match in snippet view article find links to article

function protein homodimerization activity Cellular component cytoplasm lipid droplet intracellular anatomical structure mitochondrion mitochondrial envelope

TM6SF2 (1,255 words) [view diff] exact match in snippet view article find links to article

TG-rich lipoproteins (TRLs) and increased cellular TG concentration and lipid droplet content, whereas TM6SF2 overexpression reduced liver cell steatosis

Protein-fragment complementation assay (1,266 words) [view diff] exact match in snippet view article find links to article

include NanoLuc and NanoBIT. A modification has also been developed for lipid droplet-associated interactions. TEV (Tobacco etch virus protease) Ubiquitin

Adipocyte protein 2 (293 words) [view diff] exact match in snippet view article find links to article

fatty acid binding hormone receptor binding Cellular component cytosol lipid droplet extracellular exosome nucleus cytoplasm Biological process white fat

NSDHL (986 words) [view diff] exact match in snippet view article find links to article

component integral component of membrane endoplasmic reticulum membrane lipid droplet membrane endoplasmic reticulum Biological process lipid metabolism labyrinthine

SPG20 (1,252 words) [view diff] exact match in snippet view article find links to article

protein ligase binding Cellular component mitochondrial outer membrane lipid droplet plasma membrane synapse cytoplasm midbody cytosol Biological process

Maya Schuldiner (1,901 words) [view diff] exact match in snippet view article find links to article

vacuole-mitochondria contact; the mitochondria-peroxisome contact, the inclusion body-lipid droplet contact, and the nucleus-mitochondria contact. They characterized the

Penicillium cecidicola (135 words) [view diff] exact match in snippet view article find links to article

(2010). "Absolute stereochemistry of pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1"

Lingyan Shi (1,988 words) [view diff] exact match in snippet view article find links to article

Kang, N., Tao, Y., Lagerwall, J., ... & Chen, X. (2024). Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK. Cell

FAAH2 (164 words) [view diff] exact match in snippet view article find links to article

hydrolase activity Cellular component integral component of membrane lipid droplet membrane Biological process arachidonic acid metabolic process Sources:Amigo

EHD1 (937 words) [view diff] exact match in snippet view article find links to article

component endosome cell projection early endosome membrane membrane lipid droplet plasma membrane cilium recycling endosome membrane platelet dense tubular

TRAP1 (787 words) [view diff] exact match in snippet view article find links to article

binding Cellular component membrane mitochondrial intermembrane space lipid droplet nucleoplasm mitochondrial matrix mitochondrion mitochondrial inner membrane

ALDH3B2 (493 words) [view diff] exact match in snippet view article find links to article

or oxo group of donors, NAD or NADP as acceptor Cellular component lipid droplet Biological process ethanol catabolic process metabolism alcohol metabolic

G0S2 (126 words) [view diff] exact match in snippet view article find links to article

Molecular function protein binding molecular function Cellular component lipid droplet mitochondrion Biological process positive regulation of extrinsic apoptotic

Aquaporin-7 (722 words) [view diff] exact match in snippet view article find links to article

membrane integral component of plasma membrane membrane cell-cell junction lipid droplet cell cortex cytoplasmic vesicle membrane cytoplasmic vesicle Biological

DHRS3 (543 words) [view diff] exact match in snippet view article find links to article

integral component of membrane endoplasmic reticulum membrane membrane lipid droplet Biological process negative regulation of retinoic acid receptor signaling

LPCAT1 (149 words) [view diff] exact match in snippet view article find links to article

integral component of membrane Golgi apparatus Golgi membrane membrane lipid droplet endoplasmic reticulum membrane endoplasmic reticulum plasma membrane

Fat storage-inducing transmembrane protein 1 (119 words) [view diff] exact match in snippet view article find links to article

lipid storage positive regulation of sequestering of triglyceride phospholipid biosynthetic process lipid droplet organization Sources:Amigo / QuickGO

PRPF19 (906 words) [view diff] exact match in snippet view article find links to article

double-strand break nuclear speck catalytic step 2 spliceosome membrane lipid droplet spindle Prp19 complex DNA replication factor A complex spliceosomal

RAB5C (473 words) [view diff] exact match in snippet view article find links to article

activity Cellular component melanosome lysosomal membrane endosome lipid droplet endocytic vesicle early endosome extracellular exosome membrane plasma

LMLN (230 words) [view diff] exact match in snippet view article find links to article

activity metallopeptidase activity metal ion binding Cellular component lipid droplet membrane focal adhesion cytoplasm cytosol Biological process cell cycle

CTDNEP1 (386 words) [view diff] exact match in snippet view article find links to article

membrane Nem1-Spo7 phosphatase complex endoplasmic reticulum nucleus lipid droplet Biological process positive regulation of triglyceride biosynthetic

RBP1 (1,213 words) [view diff] exact match in snippet view article find links to article

all-trans-retinol binding Cellular component nucleoplasm cytoplasm cytosol lipid droplet Biological process retinoic acid biosynthetic process retinoid metabolic

STARD13 (718 words) [view diff] exact match in snippet view article find links to article

binding GTPase activator activity Cellular component cytoplasm cytosol lipid droplet mitochondrial membranes mitochondrion membrane Biological process negative

HSD17B11 (584 words) [view diff] exact match in snippet view article find links to article

activity Cellular component cytoplasm extracellular region cytosol lipid droplet Biological process estrogen biosynthetic process androgen catabolic

PITPNM1 (817 words) [view diff] exact match in snippet view article find links to article

phosphatidylcholine transporter activity Cellular component Golgi cisterna membrane lipid droplet Golgi apparatus midbody cleavage furrow intracellular anatomical structure

PLA2G4A (1,023 words) [view diff] exact match in snippet view article find links to article

membrane cytoplasmic vesicle mitochondrial inner membrane cytoplasm lipid droplet cytosol nucleus Biological process phospholipid metabolic process phosphatidylinositol

Ectodysplasin A (1,239 words) [view diff] exact match in snippet view article find links to article

integral component of plasma membrane extracellular region cytoskeleton lipid droplet intracellular membrane-bounded organelle Biological process trachea

Spastin (1,032 words) [view diff] exact match in snippet view article find links to article

cytoplasmic vesicle nucleus cytoskeleton axon cytoplasm nuclear membrane lipid droplet endoplasmic reticulum membrane nucleoplasm cytosol endoplasmic reticulum

Caveolin 1 (1,555 words) [view diff] exact match in snippet view article find links to article

acrosomal membrane basolateral plasma membrane cytoplasmic vesicle lipid droplet cytoplasm protein-containing complex sarcolemma Biological process caveolin-mediated

C16orf58 (568 words) [view diff] exact match in snippet view article find links to article

in the endoplasmic reticulum and is thought to be important in the lipid droplet morphology. TSC22D4 The third interacting protein is TSC22D4, TSC22

Vitellogenesis (576 words) [view diff] exact match in snippet view article find links to article

digenean Crepidostomum metoecus. GER: granular endoplasmic reticulum; L: lipid droplet; M: mitochondrion; N: nucleus; Nl: nucleolus; SG: shell globule; SGC:

PM20D1 (651 words) [view diff] exact match in snippet view article find links to article

Jones JE, Puri V, Fried SK (April 2019). "Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo". Journal

Protein SET (1,281 words) [view diff] exact match in snippet view article find links to article

nucleoplasm endoplasmic reticulum perinuclear region of cytoplasm nucleus lipid droplet protein-containing complex Biological process negative regulation of

ACSL3 (1,075 words) [view diff] exact match in snippet view article find links to article

reticulum membrane membrane intracellular membrane-bounded organelle lipid droplet peroxisomal membrane peroxisome mitochondrial outer membrane endoplasmic

GBF1 (881 words) [view diff] exact match in snippet view article find links to article

phosphatidylinositol-3,4,5-trisphosphate binding lipid binding Cellular component lipid droplet Golgi membrane trans-Golgi network cell leading edge peroxisome cytoplasm

RAP1B (939 words) [view diff] exact match in snippet view article find links to article

component cytoplasm cytosol membrane cell-cell junction plasma membrane lipid droplet intracellular anatomical structure cell junction membrane raft extracellular

Squalene (1,790 words) [view diff] exact match in snippet view article find links to article

emulsion adjuvants perturb metabolism of neutral lipids and enhance lipid droplet formation". Biochemical and Biophysical Research Communications. 393

Annexin A2 (1,760 words) [view diff] exact match in snippet view article find links to article

endosome membrane late endosome membrane melanosome ruffle plasma membrane lipid droplet myelin sheath adaxonal region Schmidt-Lanterman incisure PCSK9-AnxA2

BCAP31 (1,228 words) [view diff] exact match in snippet view article find links to article

reticulum membrane membrane Sec61 translocon complex Golgi membrane lipid droplet perinuclear endoplasmic reticulum integral component of plasma membrane

Diacylglycerol O-acyltransferase 2 (629 words) [view diff] exact match in snippet view article find links to article

integral component of membrane intracellular membrane-bounded organelle lipid droplet perinuclear region of cytoplasm integral component of endoplasmic reticulum

Sphaerosporella brunnea (1,723 words) [view diff] exact match in snippet view article find links to article

droplets and large vacuoles", while mature spores contain a "very large lipid droplet, almost filling the spore". S. brunnea is not thought to be toxic, and

TMEM19 (1,144 words) [view diff] exact match in snippet view article find links to article

melanocortin 4 receptor [Homo sapiens (Human)] - Gene - NCBI". "BSCL2 BSCL2 lipid droplet biogenesis associated, seipin [Homo sapiens (Human)] - Gene - NCBI"

TSC1 (2,369 words) [view diff] exact match in snippet view article find links to article

complex cytoskeleton cytosol nucleus perinuclear region of cytoplasm lipid droplet plasma membrane cell projection protein-containing complex chaperone

AIFM2 (1,456 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm integral component of membrane cytosol lipid droplet membrane mitochondrion mitochondrial outer membrane extracellular space

CKAP4 (1,499 words) [view diff] exact match in snippet view article find links to article

cytoplasm perinuclear region of cytoplasm integral component of membrane lipid droplet plasma membrane lamellar granule extracellular exosome cytoskeleton

RAB7A (2,315 words) [view diff] exact match in snippet view article find links to article

membrane late endosome membrane extrinsic component of lysosome membrane lipid droplet melanosome membrane retromer complex lysosomal membrane autophagosome

TRAF6 (2,350 words) [view diff] exact match in snippet view article find links to article

necrosis factor receptor binding Cellular component cytoplasm cytosol lipid droplet perinuclear region of cytoplasm cytoplasmic side of plasma membrane

Lanosterol synthase (2,582 words) [view diff] exact match in snippet view article find links to article

synthase activity beta-amyrin synthase activity Cellular component lipid droplet endoplasmic reticulum membrane endoplasmic reticulum membrane Biological

Sigma-1 receptor (3,052 words) [view diff] exact match in snippet view article find links to article

cell projection endoplasmic reticulum membrane membrane growth cone lipid droplet plasma membrane synapse integral component of plasma membrane cell junction

DFFA (1,405 words) [view diff] exact match in snippet view article find links to article

activity deoxyribonuclease inhibitor activity Cellular component cytosol lipid droplet intracellular anatomical structure nucleus nucleoplasm cytoplasm plasma

Fig4 (2,785 words) [view diff] exact match in snippet view article find links to article

reticulum early endosome membrane endosome membrane Golgi apparatus lipid droplet intracellular membrane-bounded organelle Biological process locomotory

Phosphatidylethanolamine N-methyltransferase (3,536 words) [view diff] exact match in snippet view article find links to article

"Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo". The Journal

Phospholipase D1 (2,142 words) [view diff] exact match in snippet view article find links to article

Marchesan D, et al. (June 2006). "PLD1 and ERK2 regulate cytosolic lipid droplet formation". Journal of Cell Science. 119 (Pt 11): 2246–57. doi:10.1242/jcs

Jennifer Stow (1,598 words) [view diff] case mismatch in snippet view article find links to article

Bozza, P.T. (ed.). "RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages". PLOS ONE. 11 (1): e0147179. Bibcode:2016PLoSO

Peptidylprolyl isomerase A (1,588 words) [view diff] exact match in snippet view article find links to article

secretion regulation of viral genome replication uncoating of virus lipid droplet organization virion assembly leukocyte migration RNA-dependent DNA biosynthetic

Glyceraldehyde 3-phosphate dehydrogenase (3,786 words) [view diff] exact match in snippet view article find links to article

membrane intracellular membrane-bounded organelle microtubule cytoskeleton lipid droplet plasma membrane perinuclear region of cytoplasm GAIT complex cytoskeleton

Peptidylprolyl isomerase D (1,678 words) [view diff] exact match in snippet view article find links to article

protein folding cellular response to UV-A viral release from host cell lipid droplet organization negative regulation of transcription by RNA polymerase

Spherosome (1,800 words) [view diff] exact match in snippet view article find links to article

olesomes, and oil droplets have all been grouped under the general term "lipid droplet", or LD for short. Publications on the subject have grown drastically

CUL3 (2,380 words) [view diff] exact match in snippet view article find links to article

Naumann M (August 2017). "Cul3 neddylation is crucial for gradual lipid droplet formation during adipogenesis". Biochimica et Biophysica Acta (BBA)

ACSL4 (2,015 words) [view diff] exact match in snippet view article find links to article

membrane mitochondrial membranes intracellular membrane-bounded organelle lipid droplet peroxisomal membrane peroxisome mitochondrial outer membrane soma endoplasmic

3D cell culturing by magnetic levitation (1,306 words) [view diff] exact match in snippet view article find links to article

droplets typical of white adipocytes in vivo, whereas only smaller lipid droplet formation is achievable in 2D. This indicates intercellular signaling

CYB5R3 (2,118 words) [view diff] exact match in snippet view article find links to article

binding Cellular component cytoplasm endoplasmic reticulum membrane lipid droplet mitochondrial outer membrane hemoglobin complex mitochondrial inner

Fluorescence-activating and absorption-shifting tag (1,829 words) [view diff] exact match in snippet view article find links to article

(2023-11-29), "A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction", bioRxiv: The Preprint Server for Biology, doi:10

IRAK1 (3,116 words) [view diff] exact match in snippet view article find links to article

protein serine/threonine kinase activity Cellular component membrane lipid droplet plasma membrane endosome membrane interleukin-1 receptor complex nucleus

Peter Tontonoz (3,035 words) [view diff] exact match in snippet view article find links to article

ER-lipid droplet contact protein that governs lipid utilization in adipocytes. He showed that the distinctive role of this protein in inhibiting lipid droplet

17β-Hydroxysteroid dehydrogenase (2,644 words) [view diff] exact match in snippet view article find links to article

Rebelo A, Kleeff J, Sunami Y (2021). "Identification of prognostic lipid droplet-associated genes in pancreatic cancer patients via bioinformatics analysis"

Algae fuel (11,882 words) [view diff] case mismatch in snippet view article find links to article

Benning, C. (2009). "RNA Interference Silencing of a Major Lipid Droplet Protein Affects Lipid Droplet Size in Chlamydomonas reinhardtii". Eukaryotic Cell.

Lipid (7,379 words) [view diff] exact match in snippet view article find links to article

review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis"

Sylvie Roke (2,410 words) [view diff] exact match in snippet view article find links to article

solid matrix, particles in solution, oil droplets in water (emulsions), lipid droplet like systems, water droplets, a micro-jet and liposomes in aqueous solution

Malvern Panalytical (2,792 words) [view diff] exact match in snippet view article find links to article

Knorr, D. (November 2009). "Rapid monitoring of cell size, vitality and lipid droplet development in the oleaginous yeast Waltomyces lipofer". Journal of

Protein–protein interaction (8,386 words) [view diff] exact match in snippet view article find links to article

enables filament sliding. Furthermore, members of the skeletal muscle lipid droplet-associated proteins family associate with other proteins, as activator

ALOX15 (5,708 words) [view diff] exact match in snippet view article find links to article

membrane extrinsic component of cytoplasmic side of plasma membrane lipid droplet plasma membrane Biological process cellular response to calcium ion

Valosin-containing protein (5,868 words) [view diff] exact match in snippet view article find links to article

break cytosol intracellular membrane-bounded organelle myelin sheath lipid droplet nucleoplasm VCP-NSFL1C complex endoplasmic reticulum Derlin-1 retrotranslocation

Nektarios Tavernarakis (4,304 words) [view diff] exact match in snippet view article find links to article

Princz A, Filippidis G, Tavernarakis N (2023). "Age-dependent nuclear lipid droplet deposition is a cellular hallmark of aging in Caenorhabditis elegans"

CSNK1D (14,740 words) [view diff] exact match in snippet view article find links to article

Simos G, Mylonis I (June 2015). "CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT