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searching for Kinetochore 151 found (241 total)

alternate case: kinetochore

Centromere protein E (996 words) [view diff] exact match in snippet view article find links to article

Yen TJ (Mar 1995). "Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24→q25 and 1q32→q41,
MIS12 (649 words) [view diff] exact match in snippet view article find links to article
200210005. PMC 2172742. PMID 12515822. "Entrez Gene: MIS12 MIS12, MIND kinetochore complex component, homolog (yeast)". Obuse, Chikashi; Iwasaki Osamu;
CENPT (553 words) [view diff] exact match in snippet view article find links to article
• chromosome, centromeric region • nucleus • kinetochore • nuclear body Biological process • kinetochore assembly • CENP-A containing nucleosome assembly
DNA replication factor CDT1 (1,427 words) [view diff] exact match in snippet view article find links to article
nucleoplasm • nuclear body • chromosome, centromeric region • chromosome • kinetochore • cytoplasm Biological process • DNA replication checkpoint signaling
2700099C18Rik (42 words) [view diff] exact match in snippet view article find links to article
kinetochore complex component pseudogene is a protein that in humans is encoded by the 2700099C18Rik gene. "Entrez Gene: NDC80 homolog, kinetochore complex
NSL1 (646 words) [view diff] exact match in snippet view article find links to article
Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene. This gene encodes a protein with two coiled-coil
NUF2 (938 words) [view diff] exact match in snippet view article find links to article
Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene. This gene encodes a protein that is highly similar to yeast Nuf2, a
SPC24 (370 words) [view diff] exact match in snippet view article find links to article
Kinetochore protein Spc24 is a protein that in humans is encoded by the SPC24 gene. GRCh38: Ensembl release 89: ENSG00000161888 - Ensembl, May 2017 GRCm38:
TTK (gene) (814 words) [view diff] exact match in snippet view article
Kinase Is Required for Mitotic Arrest Induced by the Loss of CENP-E from Kinetochores". Mol. Biol. Cell. 14 (4): 1638–51. doi:10.1091/mbc.02-05-0074. PMC 153128
KIF2C (897 words) [view diff] exact match in snippet view article find links to article
CENP-H multimers colocalize with CENP-A and CENP-C at active centromere--kinetochore complexes". Hum. Mol. Genet. 9 (19): 2919–26. doi:10.1093/hmg/9.19.2919
KIF18A (602 words) [view diff] exact match in snippet view article find links to article
activity Cellular component • cytoplasm • cytosol • cell projection • kinetochore microtubule • kinesin complex • ruffle • microtubule cytoskeleton • microtubule
CENPK (451 words) [view diff] exact match in snippet view article find links to article
centromeric region • chromosome • kinetochore Biological process • CENP-A containing nucleosome assembly • kinetochore assembly • mitotic sister chromatid
CLASP2 (688 words) [view diff] exact match in snippet view article find links to article
Maiato H, Fairley EA, Rieder CL, et al. (2003). "Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics". Cell. 113 (7):
Dynactin (2,848 words) [view diff] exact match in snippet view article find links to article
(Plk1) to kinetochores through cyclin dependent kinase 1 (Cdk1)-phosphorylated DCTN6/p27, which is involved in proper microtubule-kinetochore attachment
Polyamine-modulated factor 1 (470 words) [view diff] exact match in snippet view article find links to article
(September 2004). "A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension". Genes & Development. 18 (18): 2255–68
Microtubule (7,393 words) [view diff] exact match in snippet view article find links to article
attach to the kinetochores can aid in chromosome congregation through lateral interaction with the kinetochores. K fibers/Kinetochore microtubules are
Nucleoporin 160 (668 words) [view diff] exact match in snippet view article find links to article
evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells". J. Cell Biol. 154 (6): 1147–60. doi:10.1083/jcb
SUGT1 (546 words) [view diff] exact match in snippet view article find links to article
homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation
NEK2 (1,172 words) [view diff] exact match in snippet view article find links to article
NINL, resulting in their displacement from the centrosomes. Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80
CHAMP1 (299 words) [view diff] exact match in snippet view article find links to article
localization to microtubule • attachment of mitotic spindle microtubules to kinetochore • protein localization to kinetochore Sources:Amigo / QuickGO
Nucleoporin 133 (888 words) [view diff] exact match in snippet view article find links to article
stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. Nup133 has been shown to interact with NUP107. GRCh38:
Chromosome 17 (1,870 words) [view diff] exact match in snippet view article find links to article
infobox on the right. 2700099C18Rik: encoding protein NDC80 homolog, kinetochore complex component pseudogene ABI3: encoding protein ABI gene family member
Kaustuv Sanyal (1,071 words) [view diff] exact match in snippet view article find links to article
Gordon Research Conference, EMBO conferences on comparative genomics and kinetochores. The Department of Biotechnology of the Government of India awarded him
MAD1L1 (513 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • GO:0001948 protein binding • kinetochore binding • identical protein binding Cellular component • centrosome • spindle
DYNC1LI1 (441 words) [view diff] exact match in snippet view article find links to article
complex • microtubule • chromosome, centromeric region • cytoskeleton • kinetochore • cytoplasm • cytosol • plasma membrane • secretory granule membrane
DYNC1LI2 (426 words) [view diff] exact match in snippet view article find links to article
complex • microtubule • cytoskeleton • cytoplasmic dynein complex • kinetochore • lysosome • late endosome • centrosome Biological process • antigen
Nucleoporin 107 (1,259 words) [view diff] exact match in snippet view article find links to article
Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Molecular Biology of the Cell. 15 (7): 3333–44. doi:10.1091/mbc
David Glover (756 words) [view diff] exact match in snippet view article find links to article
the localisation and function of Polo kinase at the centrosome, the kinetochore and the central spindle in cytokinesis was highly conserved in human
Whitehead Institute (1,966 words) [view diff] exact match in snippet view article find links to article
to regulate genes in plants and animals Iain Cheeseman – studies the kinetochore, the group of proteins that assemble at the centromere and that are required
NAS Award in Molecular Biology (1,692 words) [view diff] exact match in snippet view article find links to article
vitro characterization of a functional kinetochore complex, and for the use of that system to explore kinetochore function. Zhijian James Chen (2012) For
ZNF207 (73 words) [view diff] exact match in snippet view article find links to article
microtubule • chromosome, centromeric region • cytoskeleton • nucleus • kinetochore • nucleoplasm Biological process • regulation of transcription, DNA-templated
AHCTF1 (411 words) [view diff] exact match in snippet view article find links to article
Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division"
DYNC1I1 (737 words) [view diff] exact match in snippet view article find links to article
microtubule • chromosome, centromeric region • cytoskeleton • nucleus • kinetochore • cytoplasmic dynein complex Biological process • antigen processing
CENPO (574 words) [view diff] exact match in snippet view article find links to article
component • chromosome • cytosol • chromosome, centromeric region • kinetochore • nucleoplasm • nucleus • Mis6-Sim4 complex Biological process • centromere
Tim J. Yen (550 words) [view diff] exact match in snippet view article find links to article
specific distribution), characterization of ATM, and identification of kinetochore assembly pathways. In 2001, Yen discovered the “mitotic checkpoint complex”
CENPI (642 words) [view diff] exact match in snippet view article find links to article
2003). "Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis". Nature Cell Biology. 5 (4): 341–5. doi:10
Sperm-associated antigen 5 (569 words) [view diff] exact match in snippet view article find links to article
centromeric region • microtubule plus-end • midbody • microtubule • kinetochore • cytoskeleton • cytoplasm • mitotic spindle pole • spindle microtubule
Conly Rieder (1,152 words) [view diff] exact match in snippet view article find links to article
list (link) Yang, Z., U.S. Tulu, P. Wadsworth and C.L. Rieder. 2007. Kinetochore dynein is required for chromosome motion and congression independent
Cytokinesis (3,129 words) [view diff] exact match in snippet view article find links to article
central spindle. The central spindle (or spindle midzone) forms when non-kinetochore microtubule fibers are bundled between the spindle poles. A number of
SMC1A (2,075 words) [view diff] exact match in snippet view article find links to article
those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this
DCTN2 (1,050 words) [view diff] exact match in snippet view article find links to article
Goldberg ML (August 1998). "ZW10 helps recruit dynactin and dynein to the kinetochore". The Journal of Cell Biology. 142 (3): 763–74. doi:10.1083/jcb.142.3
PAFAH1B1 (1,498 words) [view diff] exact match in snippet view article find links to article
2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". The Journal of Cell Biology. 156 (6): 959–68. doi:10.1083/jcb
SGOL2 (1,152 words) [view diff] exact match in snippet view article find links to article
Kitajima TS; Kawashima SA; Watanabe Y (February 2004). "The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis". Nature
RCC2 (730 words) [view diff] exact match in snippet view article find links to article
passenger complex localization to kinetochore • positive regulation of attachment of spindle microtubules to kinetochore • focal adhesion assembly • GO:0034259
NCAPG2 (410 words) [view diff] exact match in snippet view article find links to article
component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores". Nature Communications. 5: 4588. Bibcode:2014NatCo
SMC2 (651 words) [view diff] exact match in snippet view article find links to article
extracellular exosome • condensed chromosome • nucleus Biological process • kinetochore organization • meiotic chromosome condensation • chromosome organization
KIAA0157 (396 words) [view diff] exact match in snippet view article find links to article
deubiquitination • cell cycle • attachment of spindle microtubules to kinetochore • protein deubiquitination • GO:0007067 mitotic cell cycle Sources:Amigo
DYNC1H1 (1,147 words) [view diff] exact match in snippet view article find links to article
2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". J. Cell Biol. United States. 156 (6): 959–68. doi:10.1083/jcb
KIF22 (1,069 words) [view diff] exact match in snippet view article find links to article
spindle • chromatin • mitotic spindle • microtubule • cytoskeleton • kinetochore • nucleus • cytoplasm • cytosol • nuclear speck Biological process •
DNAI1 (802 words) [view diff] exact match in snippet view article find links to article
(2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". Journal of Cell Biology. 156 (6): 959–968. doi:10.1083/jcb
KRP (biochemistry) (201 words) [view diff] exact match in snippet view article
a KRP that is involved in resolving errors during mitosis involving kinetochore-microtubules. This process is associated with Aurora B Protein Kinase
Aurora A kinase (2,705 words) [view diff] exact match in snippet view article find links to article
during prometaphase. It is directly involved in the interaction of the kinetochore, the part of the chromosome at which the mitotic spindle attaches and
SEC13 (804 words) [view diff] exact match in snippet view article find links to article
Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Mol. Biol. Cell. 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878
DYNLL1 (1,527 words) [view diff] exact match in snippet view article find links to article
spindle • microtubule • cytoskeleton • extracellular exosome • nucleus • kinetochore • cytoplasmic dynein complex • cilium • tertiary granule membrane • ficolin-1-rich
PSEN2 (1,098 words) [view diff] exact match in snippet view article find links to article
• Z disc • endoplasmic reticulum • perinuclear region of cytoplasm • kinetochore • mitochondrial inner membrane • lysosomal membrane • cell cortex • cell
Separase (1,033 words) [view diff] exact match in snippet view article find links to article
Stegmeier F, Visintin R, Amon A (January 2002). "Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization
Nucleoporin 43 (787 words) [view diff] exact match in snippet view article find links to article
Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Molecular Biology of the Cell. 15 (7): 3333–44. doi:10.1091/mbc
SMC4 (748 words) [view diff] exact match in snippet view article find links to article
segregation • meiotic chromosome segregation • cell division • cell cycle • kinetochore organization • mitotic chromosome condensation • meiotic chromosome condensation
Nucleoporin 85 (924 words) [view diff] exact match in snippet view article find links to article
Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Molecular Biology of the Cell. 15 (7): 3333–44. doi:10.1091/mbc
Adenomatous polyposis coli (3,148 words) [view diff] exact match in snippet view article find links to article
nucleus • lamellipodium • membrane • Wnt signalosome • centrosome • kinetochore • bicellular tight junction • ruffle membrane • plasma membrane • lateral
PHF6 (1,100 words) [view diff] exact match in snippet view article find links to article
Cellular component • nucleolus • chromosome, centromeric region • nucleus • kinetochore • nucleoplasm • chromosome Biological process • regulation of transcription
HNRPU (1,287 words) [view diff] exact match in snippet view article find links to article
regulator complex • inactive sex chromosome • ribonucleoprotein complex • kinetochore • centrosome • midbody • mitotic spindle • mitotic spindle midzone •
Securin (562 words) [view diff] exact match in snippet view article find links to article
Stegmeier F, Visintin R, Amon A (January 2002). "Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization
MAD2L1 (1,967 words) [view diff] exact match in snippet view article find links to article
(September 2002). "Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells". J. Cell Biol. 158 (5): 841–7. doi:10
40S ribosomal protein S27 (1,348 words) [view diff] exact match in snippet view article find links to article
Nigg EA (Sep 2002). "Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2". Science. 297 (5590): 2267–70. Bibcode:2002Sci
KAT8 regulatory NSL complex subunit 1 (703 words) [view diff] exact match in snippet view article find links to article
complex • MLL1 complex • chromosome, centromeric region • nucleus • kinetochore • chromosome • nucleoplasm • NSL complex Biological process • histone
Mary Dasso (1,120 words) [view diff] exact match in snippet view article find links to article
complex proteins, called nucleoporins, localize to mitotic spindles and kinetochores; this localization is essential for proper spindle assembly and cell
Centromere protein B (1,165 words) [view diff] exact match in snippet view article find links to article
Ohndorf S, Benndorf K, Diekmann S (January 2008). "Assembly of the inner kinetochore proteins CENP-A and CENP-B in living human cells". ChemBioChem. 9 (1):
ORC2 (1,476 words) [view diff] exact match in snippet view article find links to article
replication origin binding Cellular component • heterochromatin • inner kinetochore • nuclear origin of replication recognition complex • centrosome • chromatin
Jason Swedlow (1,209 words) [view diff] exact match in snippet view article find links to article
Swedlow, J. R. (2010). "Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis" (PDF). The Journal of Cell Biology. 191 (1):
GSG2 (389 words) [view diff] exact match in snippet view article find links to article
phosphorylation involved in chromosome passenger complex localization to kinetochore • mitotic sister chromatid cohesion • protein localization to chromosome
DCTN1 (1,601 words) [view diff] exact match in snippet view article find links to article
• cell leading edge • dynein complex • microtubule • cytoskeleton • kinetochore • microtubule organizing center • nucleus • nuclear envelope • centriole
CBX5 (gene) (2,400 words) [view diff] exact match in snippet view article
Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nature Cell Biology. 6 (11): 1135–41. doi:10.1038/ncb1187
Monopolin (85 words) [view diff] exact match in snippet view article find links to article
Amon A, Harrison SC (August 2010). "The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments". Cell. 142
NUDCD2 (329 words) [view diff] exact match in snippet view article find links to article
anatomical structure • chromosome, centromeric region • cytoskeleton • kinetochore • chromosome • microtubule organizing center • cytoplasm Biological process
SS18L1 (643 words) [view diff] exact match in snippet view article find links to article
component • nBAF complex • nuclear body • chromosome, centromeric region • kinetochore • chromosome • nucleus • cytosol Biological process • positive regulation
Xenopus (6,113 words) [view diff] exact match in snippet view article find links to article
regulating spindle morphogenesis and to identify new proteins that mediate kinetochore attachment to microtubules. Cell-free systems have recently become practical
NUP98 (1,515 words) [view diff] exact match in snippet view article find links to article
ring • nuclear inclusion body • nuclear pore nuclear basket • nucleus • kinetochore • nuclear pore cytoplasmic filaments • nucleoplasm • intracellular membrane-bounded
CFDP1 (584 words) [view diff] exact match in snippet view article find links to article
molecular function Cellular component • chromosome, centromeric region • kinetochore • chromosome • cellular component Biological process • multicellular
DCTN4 (337 words) [view diff] exact match in snippet view article find links to article
cytoskeleton • nucleus • dynactin complex • microtubule organizing center • kinetochore • spindle pole • stress fiber • focal adhesion • cell cortex • sarcomere
PHF2 (205 words) [view diff] exact match in snippet view article find links to article
nucleoplasm • chromosome • nucleolus • chromosome, centromeric region • kinetochore • nucleus Biological process • regulation of transcription, DNA-templated
MIS18A (575 words) [view diff] exact match in snippet view article find links to article
MIS18A, B28, C21orf45, C21orf46, FASP1, MIS18alpha, hMis18alpha, MIS18 kinetochore protein A External IDs OMIM: 618137 MGI: 1913828 HomoloGene: 41294 GeneCards:
Apc, wnt signaling pathway regulator (615 words) [view diff] exact match in snippet view article find links to article
nucleus • lamellipodium • membrane • Wnt signalosome • centrosome • kinetochore • bicellular tight junction • ruffle membrane • plasma membrane • lateral
NDE1 (778 words) [view diff] exact match in snippet view article find links to article
furrow • microtubule • chromosome, centromeric region • cytoskeleton • kinetochore • kinesin complex Biological process • cell differentiation • centrosome
IK (gene) (304 words) [view diff] exact match in snippet view article
mitotic spindle assembly checkpoint signaling • protein localization to kinetochore • mRNA processing • RNA splicing • GO:0022415 viral process • mRNA splicing
Kinesin 8 (257 words) [view diff] exact match in snippet view article find links to article
depolymerizers. During prometaphase of mitosis, the microtubules attach to the kinetochores of sister chromatids. Kinesin 8 is thought to play some role in this
CLIP1 (1,099 words) [view diff] exact match in snippet view article find links to article
filament • cytoplasmic vesicle membrane • GO:0016023 cytoplasmic vesicle • kinetochore • nuclear envelope • cytoplasm Biological process • microtubule bundle
ITGB3BP (804 words) [view diff] exact match in snippet view article find links to article
nucleoplasm • chromosome • chromosome, centromeric region • nucleus • kinetochore Biological process • regulation of transcription, DNA-templated • CENP-A
CDC20 (3,290 words) [view diff] exact match in snippet view article find links to article
(September 2002). "Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells". J. Cell Biol. 158 (5): 841–7. doi:10
Cdc14 (2,755 words) [view diff] exact match in snippet view article find links to article
cell cycle and DNA replication, or that associate with the spindle or kinetochore. Work in other yeasts further complicated the understanding of the role
SENP6 (789 words) [view diff] exact match in snippet view article find links to article
small protein removal • regulation of spindle assembly • protein sumoylation • proteolysis • regulation of kinetochore assembly Sources:Amigo / QuickGO
MEAF6 (642 words) [view diff] exact match in snippet view article find links to article
histone acetyltransferase complex • nucleus • nucleolus • chromosome • kinetochore • chromosome, centromeric region • nucleoplasm • NuA3a histone acetyltransferase
Carpediemonas (1,458 words) [view diff] exact match in snippet view article find links to article
subunits of polymerases delta and epsilon, as well as most structural kinetochore subunits, a microtubule plus-end tracking complex and all subunits of
POGZ (596 words) [view diff] exact match in snippet view article find links to article
nucleoplasm • cytosol • histone methyltransferase complex Biological process • kinetochore assembly • cell cycle • mitotic sister chromatid cohesion • cell division
ACTR1A (1,193 words) [view diff] exact match in snippet view article find links to article
neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins". Hum. Mol. Genet. 9 (2): 175–85. doi:10.1093/hmg/9
COPS7A (708 words) [view diff] exact match in snippet view article find links to article
Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nat. Cell Biol. 6 (11): 1135–41. doi:10.1038/ncb1187
Microtubule associated scaffold protein 2 (343 words) [view diff] exact match in snippet view article find links to article
TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosis". J. Biol
HSF1 (2,411 words) [view diff] exact match in snippet view article find links to article
pole • ribonucleoprotein complex • chromosome, centromeric region • kinetochore • spindle pole • nucleoplasm • chromosome • microtubule organizing center
SUMO3 (983 words) [view diff] exact match in snippet view article find links to article
ligase binding Cellular component • cytoplasm • PML body • nucleus • kinetochore • nucleoplasm Biological process • negative regulation of DNA binding
Hesperadin (220 words) [view diff] exact match in snippet view article find links to article
small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint"
TP53BP1 (1,704 words) [view diff] exact match in snippet view article find links to article
chromosome • chromosome, telomeric region • chromosome, centromeric region • kinetochore • nuclear body • nucleus • replication fork • site of double-strand break
RASSF2 (848 words) [view diff] exact match in snippet view article find links to article
Cellular component • cytoplasm • nucleus • chromosome, centromeric region • kinetochore • chromosome • nucleoplasm • Golgi apparatus • cytosol • plasma membrane
UBTF (1,260 words) [view diff] exact match in snippet view article find links to article
PMID 8641287. Pluta AF, Earnshaw WC (1996). "Specific interaction between human kinetochore protein CENP-C and a nucleolar transcriptional regulator". J. Biol. Chem
MLF1IP (735 words) [view diff] exact match in snippet view article find links to article
Park JE, Yu LR, et al. (2006). "Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation"
Cyclin-dependent kinase 1 (2,883 words) [view diff] exact match in snippet view article find links to article
drug • cellular response to hydrogen peroxide • protein localization to kinetochore • apoptotic process • cell population proliferation • proteasome-mediated
Survivin (8,364 words) [view diff] exact match in snippet view article find links to article
the kinetochore attachments, survivin then associates with the kinetochores. At anaphase as separation of the chromatids happens, the kinetochore microtubules
ECT2 (1,045 words) [view diff] exact match in snippet view article find links to article
signal transduction • regulation of attachment of spindle microtubules to kinetochore • regulation of small GTPase mediated signal transduction • protein homooligomerization
DCTN3 (578 words) [view diff] exact match in snippet view article find links to article
• cleavage furrow • chromosome, centromeric region • cytoskeleton • kinetochore • nucleolus • cytosol • microtubule Biological process • antigen processing
PPP1CC (1,210 words) [view diff] exact match in snippet view article find links to article
mitochondrion • cleavage furrow • chromosome, centromeric region • nucleus • kinetochore • protein phosphatase type 1 complex • protein-containing complex • presynapse
KAT8 (929 words) [view diff] exact match in snippet view article find links to article
chromosome • MLL1 complex • histone acetyltransferase complex • nucleus • kinetochore • MSL complex • nuclear matrix Biological process • myeloid cell differentiation
C8orf58 (609 words) [view diff] exact match in snippet view article find links to article
(Centromere Protein H) plays a critical role in centromere structure, kinetochore formation, and sister chromatid separation. MetG1 (Methionine—tRNA ligase)
RAB11A (1,387 words) [view diff] exact match in snippet view article find links to article
multivesicular body • trans-Golgi network • Golgi apparatus • cytosol • kinetochore microtubule • axon • spindle pole • membrane • centrosome • perinuclear
CDC42 (3,426 words) [view diff] exact match in snippet view article find links to article
kinase activity • regulation of attachment of spindle microtubules to kinetochore • regulation of small GTPase mediated signal transduction • positive
RANGAP1 (1,409 words) [view diff] exact match in snippet view article find links to article
Karpova TS, McNally JG, Dasso M (2002). "SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles". J. Cell Biol. 156 (4): 595–602. doi:10.1083/jcb
NUDC (1,073 words) [view diff] exact match in snippet view article find links to article
BR, Yu-Lee LY (Jul 2006). "NudC is required for Plk1 targeting to the kinetochore and chromosome congression". Current Biology. 16 (14): 1414–21. doi:10
Kinesin 13 (576 words) [view diff] exact match in snippet view article find links to article
chromatids, and this is accomplished in part during anaphase A when "kinetochore microtubules (or kMTs)" that link the sister chromatids to opposite spindle
BECN1 (1,411 words) [view diff] exact match in snippet view article find links to article
positive regulation of attachment of mitotic spindle microtubules to kinetochore • amyloid-beta metabolic process • neuron development • defense response
PCAF (2,218 words) [view diff] exact match in snippet view article find links to article
complex • histone acetyltransferase complex • A band • actomyosin • kinetochore • Ada2/Gcn5/Ada3 transcription activator complex • nucleus • cytoplasm
SEPT6 (1,099 words) [view diff] exact match in snippet view article find links to article
• chromosome, centromeric region • cytoskeleton • synaptic vesicle • kinetochore • chromosome • septin ring • septin collar • septin complex • sperm annulus
DCTN5 (685 words) [view diff] exact match in snippet view article find links to article
• nuclear membrane • chromosome, centromeric region • cytoskeleton • kinetochore • nucleoplasm • chromosome Biological process • endoplasmic reticulum
Casein kinase 1, alpha 1 (340 words) [view diff] exact match in snippet view article find links to article
centromeric region • cytoskeleton • beta-catenin destruction complex • kinetochore • nucleus • cytosol • cilium • cell projection • ciliary basal body •
SEPT2 (1,252 words) [view diff] exact match in snippet view article find links to article
centromeric region • cytoskeleton • extracellular exosome • nucleus • kinetochore • cytosol • sperm annulus • non-motile cilium • cilium • septin ring
XPO1 (2,016 words) [view diff] exact match in snippet view article find links to article
organelle • nuclear envelope • nucleoplasm • annulate lamellae • nucleus • kinetochore • nucleolus • cytosol • host cell • protein-containing complex • ribonucleoprotein
Polo-like kinase (1,469 words) [view diff] exact match in snippet view article find links to article
cytokinesis, Plks associate with several structures including the centrosome, kinetochores, and the central spindle. The catalytic serine/threonine kinase domain
PPP1R12A (1,081 words) [view diff] exact match in snippet view article find links to article
phosphatase complex • actin cytoskeleton • contractile fiber • A band • kinetochore • cytoplasm • cytosol • cytoskeleton Biological process • regulation
SEPT7 (1,186 words) [view diff] exact match in snippet view article find links to article
centromeric region • cytoskeleton • extracellular exosome • nucleus • kinetochore • cytoplasm • sperm annulus • non-motile cilium • septin ring • microtubule
NFE2L1 (3,647 words) [view diff] exact match in snippet view article find links to article
expression of genes encoding components of the spindle assembly and kinetochore. Nfe2l1 has also been shown to sense and respond to excess cholesterol
Karyotype (5,759 words) [view diff] exact match in snippet view article find links to article
2013. Retrieved 10 May 2018. Godfrey LR, Masters JC (August 2000). "Kinetochore reproduction theory may explain rapid chromosome evolution". Proc. Natl
Melina Schuh (818 words) [view diff] exact match in snippet view article find links to article
Blayney, Martyn; Elder, Kay; Schuh, Melina (15 December 2015). "Sister kinetochore splitting and precocious disintegration of bivalents could explain the
Sally Hughes-Schrader (316 words) [view diff] exact match in snippet view article find links to article
Retrieved 14 July 2014. Hughes-Schrader, Sally (Dec 1943). "Polarization, Kinetochore Movements, and Bivalent Structure in the Meiosis of Male Mantids". The
Anaphase-promoting complex (4,164 words) [view diff] exact match in snippet view article find links to article
sister-kinetochores are attached to opposite poles of the mitotic spindle, a process known as chromosome biorientation. When all kinetochores are properly
RNF4 (1,127 words) [view diff] exact match in snippet view article find links to article
transcription, DNA-templated • protein K11-linked ubiquitination • regulation of kinetochore assembly • protein K48-linked ubiquitination • protein K6-linked ubiquitination
PSEN1 (3,108 words) [view diff] exact match in snippet view article find links to article
ciliary rootlet • neuron projection • gamma-secretase complex • nucleus • kinetochore • centrosome • rough endoplasmic reticulum • dendritic shaft • aggresome
Cyclin B1 (3,254 words) [view diff] exact match in snippet view article find links to article
division • positive regulation of attachment of spindle microtubules to kinetochore • protein phosphorylation • mitotic nuclear membrane disassembly • positive
INCENP (1,487 words) [view diff] exact match in snippet view article find links to article
complex • chromosome, centromeric region • microtubule • cytoskeleton • kinetochore • nucleus • cytosol • nuclear body • midbody • protein-containing complex
NDEL1 (1,318 words) [view diff] exact match in snippet view article find links to article
hillock • microtubule • chromosome, centromeric region • cytoskeleton • kinetochore • axon cytoplasm • cytosol • central region of growth cone • centrosome
Catch bond (5,490 words) [view diff] exact match in snippet view article find links to article
cadherin-catenin complex with actin, vinculin with F-actin, microtubule with kinetochore particle, integrin alpha L beta 2 and intercellular adhesion molecule
SIN3A (3,125 words) [view diff] exact match in snippet view article find links to article
repressor complex • nucleoplasm • nucleolus • chromatin • nucleus • kinetochore • Sin3 complex • protein-containing complex Biological process • negative
Pseudoenzyme (1,375 words) [view diff] exact match in snippet view article find links to article
nucleating the CENP-I, CENP-H, CENP-K small GTPase complex to regulate kinetochore assembly Regulation of protein localisation in a cell Yeast light intermediate
Aurora inhibitor (1,105 words) [view diff] exact match in snippet view article find links to article
small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint"
ERCC excision repair 6 like, spindle assembly checkpoint helicase (661 words) [view diff] exact match in snippet view article find links to article
• cytosol • membrane • chromosome • chromosome, centromeric region • kinetochore Biological process • cell division • cell cycle • Establishment of sister
CCDC190 (2,084 words) [view diff] exact match in snippet view article find links to article
and functional organization of the Ska complex, a key component of the kinetochore-microtubule interface". Molecular Cell. 46 (3): 274–86. doi:10.1016/j
RACGAP1 (1,641 words) [view diff] exact match in snippet view article find links to article
proliferation • cell cycle • regulation of attachment of spindle microtubules to kinetochore • regulation of small GTPase mediated signal transduction • signal transduction
Nucleolar and spindle associated protein 1 (573 words) [view diff] exact match in snippet view article find links to article
SY, Chen ES, Liou YC (January 2016). "NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity". Sci Rep
Karen Oegema (832 words) [view diff] exact match in snippet view article find links to article
identify and characterize multiple proteins involved in the regulation of kinetochores and their role in chromosome segregation, known now as CENP-AHCP-3, CENP-CHCP-4
Sirtuin 2 (3,647 words) [view diff] exact match in snippet view article find links to article
deacetylation • positive regulation of attachment of spindle microtubules to kinetochore • GO:0007126 meiotic cell cycle • cellular response to caloric restriction
Paul Khavari (1,356 words) [view diff] exact match in snippet view article find links to article
Aaron; Kim, Jinah (October 2014). "Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma". Nature Genetics. 46
Condensin (7,338 words) [view diff] exact match in snippet view article find links to article
component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores". Nat Commun. 5: 4588. Bibcode:2014NatCo
FAM98A (2,452 words) [view diff] exact match in snippet view article find links to article
Phyre2 found the most similar protein to be the human protein NDC80 kinetochore complex component, a nuclear protein that binds to microtubules. FAM98A
Chromosome 1 open reading frame 112 (1,613 words) [view diff] exact match in snippet view article find links to article
McEwen BF (February 2005). "Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites". Molecular
Stress granule (12,979 words) [view diff] exact match in snippet view article find links to article
G-patch domain-containing protein 2 SUGT1 SUGT1 SGT1 Homolog, MIS12 Kinetochore Complex Assembly Cochaperone SUN1 SUN1 SUN domain-containing protein