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searching for CDC42 128 found (257 total)

alternate case: cDC42

TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article

Activated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. TNK2 gene encodes a non-receptor tyrosine kinase
CDC42BPA (954 words) [view diff] exact match in snippet view article find links to article
(CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and
SNX9 (1,009 words) [view diff] case mismatch in snippet view article find links to article
its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor
PAK2 (2,164 words) [view diff] case mismatch in snippet view article find links to article
at-large. The human PAK2 was identified as a downstream effector of Rac or Cdc42. The PAK2 gene is about 92.7-kb long. The gene contains 15 exons and generates
PARD3 (1,118 words) [view diff] exact match in snippet view article find links to article
division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide
Cdc42 effector protein 5 (194 words) [view diff] exact match in snippet view article find links to article
CDC42 effector protein 5 is a protein that in humans is encoded by the CDC42EP5 gene. Cell division control protein 42 (CDC42), a small Rho GTPase, regulates
ARHGEF9 (510 words) [view diff] case mismatch in snippet view article find links to article
characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42". J Biol Chem. 274 (47): 33587–93. doi:10.1074/jbc.274.47.33587. PMID 10559246
GPR97 (850 words) [view diff] case mismatch in snippet view article find links to article
cell adhesion and migration through regulating the small GTPase RhoA and cdc42. In vertebrates, GPR97 has an indispensable role in the bone morphogenetic
RHOQ (1,273 words) [view diff] case mismatch in snippet view article find links to article
cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42". Nat. Cell Biol. 2 (8). ENGLAND: 531–9. doi:10.1038/35019573. ISSN 1465-7392
LIMK1 (1,420 words) [view diff] case mismatch in snippet view article find links to article
Gill GN (September 1999). "Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics". Nat. Cell Biol. 1 (5):
GPR97 (850 words) [view diff] case mismatch in snippet view article find links to article
cell adhesion and migration through regulating the small GTPase RhoA and cdc42. In vertebrates, GPR97 has an indispensable role in the bone morphogenetic
GEFT (508 words) [view diff] exact match in snippet view article find links to article
RAC/CDC42 exchange factor, also known as GEFT, is a human gene. GEFT has been shown to interact with RHOA. GRCh38: Ensembl release 89: ENSG00000240771
S1PR1 (2,076 words) [view diff] exact match in snippet view article find links to article
stimulation by S1P. The signal pathway involves RAC-CDC42 and correlates with ERK1 and ERK2 activation. The RAC-CDC42 pathway leads to cell migration, whereas the
FNBP1 (1,121 words) [view diff] case mismatch in snippet view article find links to article
the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil
FGD4 (463 words) [view diff] case mismatch in snippet view article find links to article
PMID 9668039. Ikeda W, Nakanishi H, Tanaka Y, et al. (2001). "Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin
LIMK2 (1,114 words) [view diff] case mismatch in snippet view article find links to article
"Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2". The Journal of Cell Biology. 147 (7): 1519–32.
PAK6 (1,650 words) [view diff] case mismatch in snippet view article find links to article
interacting kinase which can be stimulated by androgen receptor but not Rac or Cdc42, like other family members. The human PAK6 gene consists of 16 exons of
PLEKHG2 (1,151 words) [view diff] case mismatch in snippet view article find links to article
containing a DH-PH domain of Clg promotes guanine nucleotide exchange of Cdc42 but does not promote guanine nucleotide exchange of Rac1 or RhoA. In addition
MCF2L (676 words) [view diff] case mismatch in snippet view article find links to article
J (Mar 2002). "A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange". The EMBO Journal. 21 (6):
SHANK1 (1,948 words) [view diff] case mismatch in snippet view article find links to article
accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42". J. Biol. Chem. 278 (21): 19220–9. doi:10.1074/jbc.M301052200. PMID 12626503
Cofilin 1 (1,199 words) [view diff] case mismatch in snippet view article find links to article
"Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2". J. Cell Biol. 147 (7): 1519–32. doi:10.1083/jcb
CLIP1 (1,099 words) [view diff] case mismatch in snippet view article find links to article
Kuroda S, Matsuura Y, Iwamatsu A, Perez F, Kaibuchi K (Jun 2002). "Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170". Cell. 109 (7): 873–85
PARVB (725 words) [view diff] case mismatch in snippet view article find links to article
et al. (2004). "The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor". Genes
SHANK2 (1,590 words) [view diff] case mismatch in snippet view article find links to article
accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42". The Journal of Biological Chemistry. 278 (21): 19220–9. doi:10.1074/jbc
ECT2 (1,051 words) [view diff] case mismatch in snippet view article find links to article
AE, Burridge K, Der CJ (2002). "RhoG signals in parallel with Rac1 and Cdc42". J. Biol. Chem. 277 (49): 47810–7. doi:10.1074/jbc.M203816200. PMID 12376551
Autotaxin (1,795 words) [view diff] case mismatch in snippet view article find links to article
SY, Park CG, Choi WS, Lee HW, Choi OH, Han JW, Lee HY (December 2002). "Cdc42 and Rac1 are necessary for autotaxin-induced tumor cell motility in A2058
SHANK3 (1,551 words) [view diff] case mismatch in snippet view article find links to article
accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42". The Journal of Biological Chemistry. 278 (21): 19220–9. doi:10.1074/jbc
NCKIPSD (978 words) [view diff] case mismatch in snippet view article find links to article
binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42". The Journal of Cell Biology. 152 (3): 471–82. doi:10.1083/jcb.152.3.471
Chromosome 17 (1,918 words) [view diff] exact match in snippet view article find links to article
subfamily J, member 2 (17q24.3) ACTG1: actin, gamma 1 (17q25) CDC42EP4: CDC42 effector protein 4 (17q25.1) USH1G: Usher syndrome 1G (autosomal recessive)
Iron response element (1,984 words) [view diff] case mismatch in snippet view article find links to article
Lim (January 1998). "Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization". Molecular
Chromosome 14 (1,831 words) [view diff] exact match in snippet view article find links to article
encoding protein Coiled-coil domain containing 88C CDC42BPB: encoding protein CDC42 binding protein kinase beta CDKL1: encoding protein Cyclin dependent kinase
Huntingtin (3,255 words) [view diff] case mismatch in snippet view article find links to article
Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C (Mar 2003). "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological
PTPRM (6,053 words) [view diff] case mismatch in snippet view article find links to article
of temporal neurites are both regulated by the Rho GTPase family member, Cdc42. Inhibition of the Rho GTPase Rac1 permitted neurite outgrowth on PTPmu
FGD2 (523 words) [view diff] exact match in snippet view article find links to article
PMID 12787561. Huber C, Mårtensson A, Bokoch GM, et al. (2008). "FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes
Pseudopodia (1,747 words) [view diff] case mismatch in snippet view article find links to article
G protein-coupled receptors, which activate GTPases of the Rho family (e.g. Cdc42, Rac) via G proteins. Rho GTPases are able to activate WASp which in turn
Dendrite (2,826 words) [view diff] exact match in snippet view article find links to article
Semaphorin/plexin-neuropilin, slit-robo, netrin-frazzled, reelin. Rac, CDC42 and RhoA serve as cytoskeletal regulators and the motor protein includes
MAP3K4 (1,109 words) [view diff] case mismatch in snippet view article find links to article
(1997). "MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42". EMBO J. 16 (16): 4961–72. doi:10.1093/emboj/16.16.4961. PMC 1170131. PMID 9305638
Neutrophil cytosolic factor 2 (900 words) [view diff] case mismatch in snippet view article find links to article
possesses a novel carboxylterminal binding site for the GTPases Rac2 and Cdc42". Biochemical and Biophysical Research Communications. 247 (2): 271–6. doi:10
RALA (2,012 words) [view diff] exact match in snippet view article find links to article
1995). "Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity". The Journal of Biological Chemistry
Integrin beta 8 (825 words) [view diff] case mismatch in snippet view article find links to article
(January 2012). "αvβ8 Integrin Interacts with RhoGDI1 to Regulate Rac1 and Cdc42 Activation and Drive Glioblastoma Cell Invasion". Mol Biol Cell. 24 (4):
Abr, rhogef and gtpase activating protein (556 words) [view diff] case mismatch in snippet view article find links to article
Heisterkamp N (April 2002). "Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs". Developmental Dynamics. 223 (4): 517–525. doi:10.1002/dvdy.10071
Central nervous system cavernous hemangioma (1,945 words) [view diff] exact match in snippet view article find links to article
still unidentified, genes. Recently it has been shown that the deletion of CDC42 in endothelial cells elicits cerebral vascular malformations, suggesting
Chromosome 22 (2,206 words) [view diff] exact match in snippet view article find links to article
protein 10 CBX7 (22q13) encoding chromobox protein homolog 7 CDC42EP1: CDC42 effector protein 1 CECR1: cat eye syndrome critical region protein 1 CHEK2
Rong Li (2,437 words) [view diff] case mismatch in snippet view article find links to article
Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase, in: Science. Vol. 299, nº 5610; 1231–1235. 2001, T. Uruno, J. Liu
RACGAP1 (1,724 words) [view diff] exact match in snippet view article find links to article
small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of
CEP250 (701 words) [view diff] case mismatch in snippet view article find links to article
PMID 11076968. Hirsch DS, Pirone DM, Burbelo PD (2001). "A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape
SRGAP1 (466 words) [view diff] case mismatch in snippet view article find links to article
neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10.1016/S0092-8674(01)00530-X
Stress fiber (3,025 words) [view diff] case mismatch in snippet view article find links to article
three Rho family GTPases: Rho, Rac, and Cdc42. When GTP-bound, Rac will cause the formation of lamellipodia, and Cdc42 will cause the formation of filopodia
CENPA (1,927 words) [view diff] case mismatch in snippet view article find links to article
Oceguera-Yanez F, Kato T, Okamoto M, Yonemura S, Terada Y, et al. (April 2004). "Cdc42 and mDia3 regulate microtubule attachment to kinetochores". Nature. 428
Palmitoyl acyltransferase (220 words) [view diff] case mismatch in snippet view article find links to article
DHHC domain. The example of substrate includes H-Ras, N-ras, R-Ras, RhoB, Cdc42 inform 2, Rab10, Galpha subunit of trimeric GTP binding proteins, Src family
SRGAP3 (580 words) [view diff] case mismatch in snippet view article find links to article
neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10.1016/S0092-8674(01)00530-X
ABCA1 (2,082 words) [view diff] case mismatch in snippet view article find links to article
steroid metabolic process platelet dense granule organization regulation of Cdc42 protein signal transduction response to nutrient lipid metabolism phospholipid
SRGAP3 (580 words) [view diff] case mismatch in snippet view article find links to article
neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10.1016/S0092-8674(01)00530-X
Stress fiber (3,025 words) [view diff] case mismatch in snippet view article find links to article
three Rho family GTPases: Rho, Rac, and Cdc42. When GTP-bound, Rac will cause the formation of lamellipodia, and Cdc42 will cause the formation of filopodia
FARP2 (484 words) [view diff] case mismatch in snippet view article find links to article
(Aug 2003). "Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin
DIAPH2 (687 words) [view diff] case mismatch in snippet view article find links to article
Kato T, Okamoto M, Yonemura S, Terada Y, Ishizaki T, Narumiya S (2004). "Cdc42 and mDia3 regulate microtubule attachment to kinetochores". Nature. 428
Shigella flexneri (2,322 words) [view diff] case mismatch in snippet view article find links to article
Sansonetti, Philippe J.; Carlier, Marie-France (1999-09-20). "Activation of the Cdc42 Effector N-Wasp by the Shigella flexneri Icsa Protein Promotes Actin Nucleation
DEF6 (467 words) [view diff] case mismatch in snippet view article find links to article
PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA". Experimental Cell Research. 294 (2): 335–44. doi:10.1016/j.yexcr
B-cell receptor (2,173 words) [view diff] case mismatch in snippet view article find links to article
domain is Bam32. This recruits and activates small GTPases such as Rac1 and Cdc42. These, in turn, are responsible for the cytoskeletal changes associated
ARHGAP26 (995 words) [view diff] case mismatch in snippet view article find links to article
1996). "An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase". Mol. Cell. Biol. 16 (6): 3169–78
DAAM1 (698 words) [view diff] case mismatch in snippet view article find links to article
diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics". Exp
RHOJ (457 words) [view diff] case mismatch in snippet view article find links to article
Meller N, Uekawa N, et al. (2005). "Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes"
GRB2 (9,353 words) [view diff] case mismatch in snippet view article find links to article
binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42". The Journal of Cell Biology. 152 (3): 471–82. doi:10.1083/jcb.152.3.471
SRGAP2 (780 words) [view diff] case mismatch in snippet view article find links to article
neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10.1016/S0092-8674(01)00530-X
InaD-like protein (933 words) [view diff] case mismatch in snippet view article find links to article
Starostine A, Metalnikov P, Pawson T (2006). "A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells". Cell. 125 (3):
BCAR3 (943 words) [view diff] case mismatch in snippet view article find links to article
factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42". J. Immunol. 170 (2): 969–78. doi:10.4049/jimmunol.170.2.969. PMID 12517963
DIAPH1 (1,260 words) [view diff] case mismatch in snippet view article find links to article
Okamoto M, Yonemura S, Terada Y, Ishizaki T, Narumiya S (April 2004). "Cdc42 and mDia3 regulate microtubule attachment to kinetochores". Nature. 428
TBC1D3 (546 words) [view diff] case mismatch in snippet view article find links to article
oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling". Mol. Cell. Biol. 23 (6): 2151–61
GIT2 (1,085 words) [view diff] case mismatch in snippet view article find links to article
assembly of GIT family ARF GTPase-activating proteins and PIX family Rac1/Cdc42 guanine nucleotide exchange factors". Cellular Signalling. 16 (9): 1001–11
AKAP9 (1,213 words) [view diff] case mismatch in snippet view article find links to article
Nelson DL, Stewart DM, Goldenring JR (Jun 2004). "AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus". Mol. Biol. Cell. 15 (6):
Klaus Hahn (cell biologist) (1,331 words) [view diff] case mismatch in snippet view article
Hodgson, V. Kraynov, A. Toutchkine, K. M. Hahn. Activation of Endogenous Cdc42 Visualized in Living Cells. Science, 305:1615-1619, 2004. Machacek, M.,
STARD8 (816 words) [view diff] case mismatch in snippet view article find links to article
Deki Y, Yagisawa H (Dec 2007). "START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology". Biochemical
ROBO1 (1,234 words) [view diff] case mismatch in snippet view article find links to article
neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10.1016/S0092-8674(01)00530-X
Protein kinase C zeta type (2,598 words) [view diff] case mismatch in snippet view article find links to article
polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C". Genes Cells. 6 (2): 107–19. doi:10.1046/j
Immunological synapse (1,807 words) [view diff] case mismatch in snippet view article find links to article
TCR/CD3 interactions with integrins and small GTPases (such as Rac1 or Cdc42). These interactions activate large multi-molecular complexes (containing
Apolipoprotein AI (2,555 words) [view diff] case mismatch in snippet view article find links to article
metabolic process positive regulation of hydrolase activity regulation of Cdc42 protein signal transduction blood vessel endothelial cell migration negative
Spermatogenesis associated 13 (300 words) [view diff] case mismatch in snippet view article find links to article
characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42". Oncogene. 26 (55): 7620–267. doi:10.1038/sj.onc.1210574. PMID 17599059
RIT2 (734 words) [view diff] case mismatch in snippet view article find links to article
development negative regulation of neuron projection development regulation of Cdc42 protein signal transduction positive regulation of MAPK cascade positive
List of MeSH codes (D12.644) (5,787 words) [view diff] case mismatch in snippet view article
gtp-binding proteins MeSH D12.644.360.525.700.050 – cdc42 gtp-binding protein MeSH D12.644.360.525.700.050.500 – cdc42 gtp-binding protein, saccharomyces cerevisiae
Apolipoprotein C-III (2,381 words) [view diff] case mismatch in snippet view article find links to article
clearance negative regulation of fatty acid biosynthetic process regulation of Cdc42 protein signal transduction lipid metabolism negative regulation of high-density
Mir-185 microRNA precursor family (970 words) [view diff] case mismatch in snippet view article find links to article
Liu S, Huang J, Zheng Y, Bi F (February 2011). "miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal
VAV2 (1,055 words) [view diff] case mismatch in snippet view article find links to article
PMC 86111. PMID 10938113. Liu BP, Burridge K (2000). "Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins"
ARPC2 (987 words) [view diff] case mismatch in snippet view article find links to article
TE, De Matteis MA, Franco M, Chavrier P (2005). "Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics"
RALBP1 (1,239 words) [view diff] exact match in snippet view article find links to article
1995). "Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity". J Biol Chem. 270 (38): 22473–7
Cell cortex (1,509 words) [view diff] case mismatch in snippet view article find links to article
regulated by diverse genes such as Rhoa, WDR1, ERM proteins, Ect2, Pbl, Cdc42, aPKC, Par6, DJ-1 and FAM134A. In cytokinesis the cell cortex plays a central
Neuropilin 1 (1,958 words) [view diff] case mismatch in snippet view article find links to article
endothelial cell migration actin cytoskeleton reorganization regulation of Cdc42 protein signal transduction substrate adhesion-dependent cell spreading
Intersectin 2 (839 words) [view diff] case mismatch in snippet view article find links to article
Tokunaga A, et al. (2006). "Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2". Mol. Biol. Cell. 17 (3): 1273–85. doi:10.1091/mbc
ARPC3 (759 words) [view diff] case mismatch in snippet view article find links to article
Dubois T, Paléotti O, Mironov AA, et al. (2005). "Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics"
Cytoskeleton (5,121 words) [view diff] case mismatch in snippet view article find links to article
contractile acto-myosin filaments ("stress fibers"), Rac for lamellipodia and Cdc42 for filopodia. Functions include: Muscle contraction Cell movement Intracellular
ARHGEF12 (1,754 words) [view diff] case mismatch in snippet view article find links to article
Burridge K, Der CJ (December 2002). "RhoG signals in parallel with Rac1 and Cdc42". The Journal of Biological Chemistry. 277 (49): 47810–7. doi:10.1074/jbc
Shootin 1 (217 words) [view diff] case mismatch in snippet view article find links to article
edge axonal growth cone perinuclear region of cytoplasm Biological process Cdc42 protein signal transduction cytoplasmic actin-based contraction involved
Netrin 1 (1,316 words) [view diff] case mismatch in snippet view article find links to article
motility axon guidance substrate-dependent cell migration, cell extension Cdc42 protein signal transduction positive regulation of axon extension inner
ABL (gene) (3,496 words) [view diff] case mismatch in snippet view article
regulation of endothelial cell migration cell differentiation regulation of Cdc42 protein signal transduction neuropilin signaling pathway endothelial cell
List of MeSH codes (D12.776.157) (4,484 words) [view diff] case mismatch in snippet view article
proteins MeSH D12.776.157.325.515.700.050 – cdc42 gtp-binding protein MeSH D12.776.157.325.515.700.050.500 – cdc42 gtp-binding protein, saccharomyces cerevisiae
Glutathione S-transferase (4,278 words) [view diff] case mismatch in snippet view article find links to article
1093/toxsci/kfs243. PMID 22872058. Benard V, Bokoch GM (2002). "Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods". G Protein Pathways
Akt/PKB signaling pathway (4,116 words) [view diff] exact match in snippet view article find links to article
Activating Kinase Akt Phosphorylation Site Details Activated CDC42 kinase 1 (Ack1) Tyr176 Akt binds preferentially to phosphatidic acid (PA) instead of
ENAH (gene) (1,096 words) [view diff] case mismatch in snippet view article
Jordens I, Gevaert K, Driessens M, Vandekerckhove J, Hall A (October 2001). "Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex"
SEPT7 (1,190 words) [view diff] case mismatch in snippet view article find links to article
"Borg proteins control septin organization and are negatively regulated by Cdc42". Nature Cell Biology. 3 (10): 861–6. doi:10.1038/ncb1001-861. PMID 11584266
Lens (vertebrate anatomy) (6,252 words) [view diff] case mismatch in snippet view article
Timothy F. (April 2016). "Lens placode planar cell polarity is dependent on Cdc42-mediated junctional contraction inhibition". Developmental Biology. 412
USP6 (1,947 words) [view diff] case mismatch in snippet view article find links to article
Oncogene Encodes a Component of a Novel Effector Pathway for Rho GTPases Cdc42 and Rac1 and Stimulates Actin Remodeling". Mol. Cell. Biol. 23 (6): 2151–61
Adenylylation (3,274 words) [view diff] exact match in snippet view article find links to article
downstream effectors. VopS also adenylates RhoA and cell division cycle 42 (CDC42), leading to a disaggregation of the actin filament network. As a result
SMURF1 (1,916 words) [view diff] case mismatch in snippet view article find links to article
Ando A, Nagase T (April 2008). "Smurf1 directly targets hPEM-2, a GEF for Cdc42, via a novel combination of protein interaction modules in the ubiquitin-proteasome
ACTR3 (1,193 words) [view diff] case mismatch in snippet view article find links to article
mediates actin polymerization induced by the small GTP-binding protein Cdc42". Proceedings of the National Academy of Sciences of the United States of
N-alpha-acetyltransferase 10 (5,405 words) [view diff] case mismatch in snippet view article find links to article
suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity". Cancer Cell. 19 (2): 218–31. doi:10.1016/j.ccr.2010.11.010
CAPZB (1,525 words) [view diff] case mismatch in snippet view article find links to article
Metalnikov P, Pawson T (May 2006). "A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells". Cell. 125 (3):
PRC1 (1,800 words) [view diff] case mismatch in snippet view article find links to article
mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase". J. Biol. Chem. 279 (16): 16394–402. doi:10.1074/jbc
Barbara Sloat (236 words) [view diff] exact match in snippet view article find links to article
licensed Paramedic in the State of Michigan since 1998. Adams, A. E., et al. "CDC42 and CDC43, two additional genes involved in budding and the establishment
Drebrin-like (1,230 words) [view diff] case mismatch in snippet view article find links to article
Estrada L, Kinley AW, Parsons JT, Vojtek AB, Gorski JL (2004). "Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin
Haptotaxis (2,092 words) [view diff] case mismatch in snippet view article find links to article
M., Boudreau, N. S., Johnson, N. M., & Heckman, C. A. (2015). Effect of Cdc42 domains on filopodia sensing, cell orientation, and haptotaxis. Cellular
FNTA (1,005 words) [view diff] case mismatch in snippet view article find links to article
Type-I Complexed with a GGPP analog and a RRCVLL Peptide Derived from Cdc42 splice isoform-2 1x81: Farnesyl transferase structure of Jansen compound
Apolipoprotein E (6,412 words) [view diff] case mismatch in snippet view article find links to article
postsynaptic membrane organization steroid metabolic process regulation of Cdc42 protein signal transduction lipid metabolism negative regulation of amyloid-beta
PTK2 (4,724 words) [view diff] case mismatch in snippet view article find links to article
1996). "An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase". Molecular and Cellular Biology.
Suzanne Eaton (1,293 words) [view diff] case mismatch in snippet view article find links to article
polarization." Cell. 82: 5. Eaton, Suzanne (December 1996). "Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila." Journal
Angiomotin (2,235 words) [view diff] case mismatch in snippet view article find links to article
Metalnikov P, Pawson T (May 2006). "A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells". Cell. 125 (3):
Schizosaccharomyces pombe (6,047 words) [view diff] case mismatch in snippet view article find links to article
controls polarized cell growth by spatial regulation of the small GTPase Cdc42". Current Biology. 19 (15): 1314–9. doi:10.1016/j.cub.2009.06.057. PMID 19646873
FYN (4,858 words) [view diff] case mismatch in snippet view article find links to article
"Stimulation of M3 muscarinic receptors induces phosphorylation of the Cdc42 effector activated Cdc42Hs-associated kinase-1 via a Fyn tyrosine kinase
Paracytophagy (2,434 words) [view diff] case mismatch in snippet view article find links to article
keratinocytes. This transfer involves a classic filopodial forming pathway, with Cdc42 and WASP as key factors. Argosomes, melanosomes, and other examples of epithelial
C-Raf (8,674 words) [view diff] case mismatch in snippet view article find links to article
exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1". J. Biol. Chem. 275 (38): 29788–93. doi:10.1074/jbc
Mechanotaxis (2,187 words) [view diff] case mismatch in snippet view article find links to article
Kursad (ed.), "Activation and Function of Small GTPases Rho, Rac, and Cdc42 During Gastrulation", Planar Cell Polarity, Methods in Molecular Biology
Mitotic exit (3,400 words) [view diff] case mismatch in snippet view article find links to article
occur only when the nucleus is correctly positioned within the bud. Cdc24, Cdc42, and Ste20 proteins, through their interaction with Lte1 and other MEN components
Juan Carlos Lacal (1,539 words) [view diff] exact match in snippet view article find links to article
& Lacal, J. C. (1997). Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins. Genes & development, 11(4), 463-475 Aznar, S., & Lacal
SCRIB (2,159 words) [view diff] case mismatch in snippet view article find links to article
belongs to a protein complex containing betaPIX, an exchange factor for Rac/Cdc42, and GIT1, a GTPase activating protein for ARF6 implicated in receptor recycling
List of MeSH codes (D12.776) (7,397 words) [view diff] no match in snippet view article
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
Madin-Darby canine kidney cells (2,699 words) [view diff] case mismatch in snippet view article find links to article
segregation of phosphoinositides controls epithelial morphogenesis through Cdc42". Cell. 128 (2): 383–397. doi:10.1016/j.cell.2006.11.051. PMC 1865103. PMID 17254974
LMTK3 (1,439 words) [view diff] exact match in snippet view article find links to article
integrin subunits. LMTK3 acts through GRB2, inducing RAS activation and CDC42 activation, leading to increased ITGA5 and ITGB1 expression through the
Optogenetics (11,915 words) [view diff] case mismatch in snippet view article find links to article
2008). "Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway". Proceedings of the National Academy of Sciences
List of MeSH codes (D08) (15,232 words) [view diff] case mismatch in snippet view article
MeSH D08.811.277.040.330.300.400.700.050 – cdc42 gtp-binding protein MeSH D08.811.277.040.330.300.400.700.060 – cdc42 gtp-binding protein, saccharomyces cerevisiae
List of MeSH codes (D08) (15,232 words) [view diff] case mismatch in snippet view article
MeSH D08.811.277.040.330.300.400.700.050 – cdc42 gtp-binding protein MeSH D08.811.277.040.330.300.400.700.060 – cdc42 gtp-binding protein, saccharomyces cerevisiae