Find link

language:

Find link is a tool written by Edward Betts.

Longer titles found: Hypoxia-inducible factor-asparagine dioxygenase (view), Hypoxia-inducible factor-proline dioxygenase (view), Hypoxia-inducible factor dioxygenase (view)

searching for Hypoxia-inducible factor 137 found (214 total)

alternate case: hypoxia-inducible factor

HIF1AN (893 words) [view diff] exact match in snippet view article find links to article

Hypoxia-inducible factor 1-alpha inhibitor (FIH) is a protein that in humans is encoded by the HIF1AN gene. FIH has been shown to interact with HIF1A and

TAZ zinc finger (508 words) [view diff] no match in snippet view article find links to article

transactivator with ED-rich tail), inhibiting the activity of the hypoxia inducible factor (HIF-1alpha) and thereby attenuating the cellular response to low

HIF-1 alpha IRES (139 words) [view diff] exact match in snippet view article find links to article

cell conditions that inhibit cap-dependent translation [1]. The hypoxia-inducible factor-1α protein (HIF-1α) is a subunit of the HIF-1 transcription factor

EGLN3 (868 words) [view diff] exact match in snippet view article find links to article

prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor". The Journal of Biological Chemistry. 279 (37): 38458–65. doi:10

Daprodustat (885 words) [view diff] exact match in snippet view article find links to article

the treatment of anemia due to chronic kidney disease. It is a hypoxia-inducible factor prolyl hydroxylase inhibitor. It is taken by mouth. The most common

USP20 (1,340 words) [view diff] exact match in snippet view article find links to article

number of proteins including thyronine deiodinase type 2 (D2), Hypoxia-inducible factor 1α (HIF1α), and β2 adrenergic receptor (β2AR). The USP20 gene is

Enarodustat (165 words) [view diff] no match in snippet view article find links to article

kidney disease (CKD). Enarodustat functions as a inhibitor of hypoxia inducible factor-proly hydroxylase (HIF-PH). The drug was approved in September

Vadadustat (978 words) [view diff] exact match in snippet view article find links to article

anemia associated with chronic kidney disease. Vadadustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor. The most common side effects include

FAM162A (987 words) [view diff] exact match in snippet view article find links to article

intrinsic apoptosis in response to hypoxia via interactions with hypoxia-inducible factor-1α (HIF-1α). As a result, it has been associated with cerebral

Temsirolimus (1,197 words) [view diff] exact match in snippet view article find links to article

effectors, the synthesis of cell cycle proteins such as cyclin D and hypoxia-inducible factor-1a (HIF-1a) are increased. HIF-1a then stimulates VEGF. Whether

Duodenal cytochrome B (643 words) [view diff] no match in snippet view article find links to article

deficiency and hypoxia on Dcytb levels are medicated via the HIF2 (Hypoxia inducible factor 2) transcription factor which binds to hypoxia response elements

Alpha-ketoglutarate-dependent hydroxylases (3,995 words) [view diff] exact match in snippet view article find links to article

Schofield CJ (March 2010). "Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain

P4HTM (353 words) [view diff] exact match in snippet view article find links to article

"Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor". J. Biol. Chem. 278 (33): 30772–80. doi:10.1074/jbc.M304982200

Roxadustat (1,135 words) [view diff] case mismatch in snippet view article find links to article

Diamond SA, Durham JH, Cangiano JL, et al. (June 2016). "Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat (FG-4592) for the Treatment

ARNT2 (729 words) [view diff] exact match in snippet view article find links to article

Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive

Paul Workman (scientist) (962 words) [view diff] case mismatch in snippet view article

Molecule Inhibitors of Hypoxia-Inducible Factor-1 That Differentially Block Hypoxia-Inducible Factor-1 Activity and Hypoxia-Inducible Factor-1α Induction in

Molidustat (396 words) [view diff] case mismatch in snippet view article find links to article

0111838. PMC 4230943. PMID 25392999. Gupta N, Wish JB (June 2017). "Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors: A Potential New Treatment for Anemia

Reverse migration (immunology) (1,448 words) [view diff] exact match in snippet view article

resolution. The activation of in vivo inflammatory pathways (such as hypoxia-inducible factor, HIF), alters this behavior of reverse migration. The introduction

N-alpha-acetyltransferase 10 (4,953 words) [view diff] exact match in snippet view article find links to article

hdl:10371/22955. PMID 17108104. Lim JH, Chun YS, Park JW (1 July 2008). "Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated

Mir-199 microRNA precursor (1,301 words) [view diff] case mismatch in snippet view article find links to article

consequence of long-term excessive alcohol use. Activation of hypoxia-Inducible Factor-1α (HIF-1α) is an indicator of hypoxia. Endothelin-1 (ET-1) is

Gabi Dachs (881 words) [view diff] exact match in snippet view article find links to article

response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1". Radiotherapy and Oncology. 75 (1): 89–98. doi:10.1016/J.RADONC

Margreet Vissers (374 words) [view diff] exact match in snippet view article find links to article

CM Vissers. "Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer

RWDD3 (458 words) [view diff] exact match in snippet view article find links to article

positive regulation of protein sumoylation positive regulation of hypoxia-inducible factor-1alpha signaling pathway Sources:Amigo / QuickGO Orthologs Species

PTPRZ1 (1,150 words) [view diff] exact match in snippet view article find links to article

(2005). "Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells". Cancer Res. 65 (8):

SAT2 (574 words) [view diff] exact match in snippet view article find links to article

essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha". J Biol Chem. 282 (32): 23572–80. doi:10.1074/jbc.M703504200

PFKFB3 (3,772 words) [view diff] exact match in snippet view article find links to article

hypoxia response elements (HREs), that recruit the binding of hypoxia-inducible factor-1 (HIF-1). Hypoxia signaling via HIF-1α stabilization upregulates

WDR83 (408 words) [view diff] exact match in snippet view article find links to article

homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative

OS9 (gene) (770 words) [view diff] exact match in snippet view article

is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis

TXN2 (1,187 words) [view diff] exact match in snippet view article find links to article

"Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha". The Journal of Biological Chemistry. 282 (10): 7482–90

Hemangioblastoma (667 words) [view diff] exact match in snippet view article find links to article

In normal circumstances, pVHL is involved in the inhibition of hypoxia-inducible factor 1 α (HIF-1α) by ubiquitin mediated proteosomal degradation. In

DDIT4 (1,505 words) [view diff] exact match in snippet view article find links to article

Skaliter R, Feinstein E (April 2002). "Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis". Molecular and

Rhapontigenin (245 words) [view diff] no match in snippet view article find links to article

S.; Chen, C. Y.; Kim, S. H. (2011). "Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate

Alessio Ciulli (1,112 words) [view diff] no match in snippet view article find links to article

Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface". Chemistry & Biology. 19 (10): 1300–1312

Succinic acid (4,550 words) [view diff] no match in snippet view article find links to article

prolyl hydroxylases (PHDs) stabilizes the transcription factor hypoxia inducible factor (HIF)1α. PHDs hydroxylate proline in parallel to oxidatively decarboxylating

Vitis coignetiae (542 words) [view diff] no match in snippet view article find links to article

S.; Chen, C. Y.; Kim, S. H. (2011). "Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate

NOX2 (2,442 words) [view diff] exact match in snippet view article find links to article

angiotensin response to nutrient cellular response to hypoxia hypoxia-inducible factor-1alpha signaling pathway cellular response to cadmium ion cellular

PDK3 (1,575 words) [view diff] exact match in snippet view article find links to article

phosphorylation peroxisome proliferator activated receptor signaling pathway hypoxia-inducible factor-1alpha signaling pathway regulation of reactive oxygen species

PFKFB4 (689 words) [view diff] exact match in snippet view article find links to article

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation". FEBS Letters. 576 (1–2): 14–20. doi:10.1016/j

Distal promoter (640 words) [view diff] no match in snippet view article find links to article

conserved prolyl residues and hydroxylates it in a α-subunit of hypoxia inducible factor (HIF). The functional polymorphism is a 4bp insertion/deletion

Thomas Kietzmann (517 words) [view diff] exact match in snippet view article find links to article

R. P. Brandes, T. Kietzmann, R. Busse: Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells role of the

Tuberous sclerosis protein (1,058 words) [view diff] exact match in snippet view article find links to article

TSC1-TSC2 by phosphorylating at least 2 residues of TSC2. Hypoxia: The Hypoxia-inducible factor α HIFα induces REDD1 at low oxygen levels. REDD1 has been shown

Clear cell papillary renal cell carcinoma (213 words) [view diff] exact match in snippet view article find links to article

immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins". Mod Pathol. 24 (9): 1207–20. doi:10

Endolymphatic sac tumor (1,182 words) [view diff] no match in snippet view article find links to article

protein is involved in up-regulation of hypoxic response via the [[hypoxia inducible factor [HIF]-1 alpha]]. Mutations generally prevent the production of

Tumor hypoxia (5,638 words) [view diff] no match in snippet view article find links to article

feature of solid tumors leading to cell metabolism adaptive changes. Hypoxia inducible factor-1α (HIF-1α) is a key oxygen-regulated transcriptional activator

Cellulite (1,559 words) [view diff] exact match in snippet view article find links to article

particular polymorphisms in the angiotensin converting enzyme (ACE) and hypoxia-inducible factor 1A (HIF1a) genes. Evidence for the heredity of cellulite is supported

FibroGen (1,671 words) [view diff] exact match in snippet view article find links to article

the body’s natural production of red blood cells by inhibiting hypoxia-inducible factor prolyl hydroxylase, thereby activating the body’s response to low

Hypoxanthine-guanine phosphoribosyltransferase (1,614 words) [view diff] no match in snippet view article find links to article

deficiency. HPRT expression on the mRNA and protein level is induced by hypoxia inducible factor 1 (HIF1A). HIF-1 is a transcription factor that directs an array

Minor physical anomalies (670 words) [view diff] no match in snippet view article find links to article

and Carrolee Barlow, April 20, 2005, Brain-specific knock-out of Hypoxia inducible factor -1alpha, reduces — rather than increases hypoxia-ischemic damage

Glycogen synthase (1,757 words) [view diff] no match in snippet view article find links to article

(12 March 2010). "Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1". PLOS ONE. 5 (3)

Hilpda (771 words) [view diff] exact match in snippet view article find links to article

is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1". FASEB J. 24 (11): 4443–58. doi:10.1096/fj.10-159806. PMID 20624928

CD47 (4,272 words) [view diff] no match in snippet view article find links to article

JOK-1 cells. Apoptosis induction appears to be regulated by the hypoxia inducible factor 1α (HIF-1α) pathway. The RAS-transformed cell lines MDFB6 and B6ras

C22orf31 (1,227 words) [view diff] exact match in snippet view article find links to article

differentiation. The presence of ARNT, which is typically associated with hypoxia-inducible factor 1 alpha, suggests a role for C22orf31 in the formation of acute

ACO1 (651 words) [view diff] exact match in snippet view article find links to article

connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin

EP300 (4,191 words) [view diff] exact match in snippet view article find links to article

This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and, thus, plays a role in the stimulation of hypoxia-induced

Mitochondrial ROS (1,146 words) [view diff] exact match in snippet view article find links to article

triggers mitochondrial ROS production, which induces stabilization of hypoxia-inducible factor-1α (HIF1A) and consequently promotes glycolysis. HIF1A-induced

Scutellarin (542 words) [view diff] exact match in snippet view article find links to article

human retinal endothelial cells through reactive oxygen species/hypoxia-inducible factor-1α/vascular endothelial growth factor pathway". Journal of Cardiovascular

MicroRNA 138-1 (712 words) [view diff] exact match in snippet view article find links to article

Cai W, Gao J, Hong B (2011). "MiR-138 suppresses expression of hypoxia-inducible factor 1α (HIF-1α) in clear cell renal cell carcinoma 786-O cells". Asian

Jonathan Simons (1,177 words) [view diff] case mismatch in snippet view article find links to article

; Simons, Jonathan W. (November 15, 1999). "Overexpression of Hypoxia-inducible Factor 1α in Common Human Cancers and Their Metastases". Cancer Research

Phyllodes tumor (2,254 words) [view diff] exact match in snippet view article find links to article

These proteins include vascular endothelial growth factor (VEGF), Hypoxia-inducible factor-1a, Platelet-derived growth factor, endothelin-1, and nitrogen

ROR2 (1,127 words) [view diff] exact match in snippet view article find links to article

PMID 19640924. Wright TM, Rathmell WK (2010). "Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma". J

Dauricine (370 words) [view diff] no match in snippet view article find links to article

(2009). "Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1alpha protein accumulation and vascular endothelial growth factor

MIR195 (699 words) [view diff] exact match in snippet view article find links to article

inflammatory protein-1beta expression in monocytic cells involves hypoxia-inducible factor-1alpha and AP-1 and is negatively regulated by microRNA-195". J

Asparagine (2,075 words) [view diff] exact match in snippet view article find links to article

hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor". Genes & Development. 16 (12): 1466–71. doi:10.1101/gad.991402

Enzo Emanuele (1,159 words) [view diff] exact match in snippet view article find links to article

particular polymorphisms in the angiotensin converting enzyme (ACE) and hypoxia-inducible factor 1A (HIF1a) genes. Emanuele E, Politi P, Bianchi M, Minoretti P

NOX1 (885 words) [view diff] exact match in snippet view article find links to article

(2004). "Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species". Free Radic. Biol. Med

NDN (gene) (1,275 words) [view diff] no match in snippet view article

Park JA, Min KJ, Kwon YW, Kim KW (2005). "Negative regulation of hypoxia inducible factor-1alpha by necdin". FEBS Lett. 579 (17): 3797–801. doi:10.1016/j

Hydrogen potassium ATPase (2,354 words) [view diff] exact match in snippet view article find links to article

(2013). "A(1) and A(3) adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes". Pharmacol Res. 76: 157–70

Ellen Heber-Katz (1,538 words) [view diff] exact match in snippet view article find links to article

molecules involved in this unusual healing response. In particular, hypoxia-inducible factor-1a (HIF-1a) was identified as a critical molecule, based on the

AlkB homolog 5, RNA demethylase (486 words) [view diff] exact match in snippet view article find links to article

nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)". PLOS ONE. 6 (1): e16210. Bibcode:2011PLoSO...616210T

P4HA1 (883 words) [view diff] exact match in snippet view article find links to article

peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases". J. Biol. Chem. 281 (39): 28712–20. doi:10

P4HA2 (804 words) [view diff] exact match in snippet view article find links to article

peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases". J. Biol. Chem. 281 (39): 28712–20. doi:10

Iron response element (1,989 words) [view diff] exact match in snippet view article find links to article

Matthias W. Hentze (May 2007). "Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency". Nature Structural & Molecular

Rubinstein–Taybi syndrome (2,322 words) [view diff] exact match in snippet view article find links to article

Eck MJ (2002). "Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α". Proceedings of the National Academy of Sciences of the United

Glucose-6-phosphate dehydrogenase (2,418 words) [view diff] exact match in snippet view article find links to article

number of glycolytic enzymes activated by the transcription factor hypoxia-inducible factor 1 (HIF1). G6PD is remarkable for its genetic diversity. Many variants

KCNN2 (1,254 words) [view diff] exact match in snippet view article find links to article

in human melanoma cells are up-regulated by hypoxia involving hypoxia-inducible factor-1α and the von Hippel-Lindau protein". The Journal of Physiology

Jacques Pouysségur (1,388 words) [view diff] no match in snippet view article find links to article

normoxia », EMBO J, (2003) 22, p. 4082-90 Berra E, et al., « The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling », EMBO Rep

Phorbol-12-myristate-13-acetate-induced protein 1 (1,320 words) [view diff] exact match in snippet view article find links to article

"BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha". J. Exp. Med. 199 (1): 113–24. doi:10.1084/jem.20030613

TYW5 (341 words) [view diff] no match in snippet view article find links to article

Protein 1 (HSPBAP1) Jumonji C Domain-Containing Protein 5 (JMJD5) Hypoxia Inducible Factor 1 Subunit Alpha Inhibitor (HIF1AN) Jumonji Domain-Containing Protein

Ubiquitin C (4,261 words) [view diff] exact match in snippet view article find links to article

"Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha". The Journal of Biological Chemistry. 283 (43): 29375–84

Pyruvate kinase (4,042 words) [view diff] exact match in snippet view article find links to article

microenvironments like hypoxia activate transcription factors like the hypoxia-inducible factor to promote the transcription of PKM2, which forms a positive feedback

David Gorski (3,345 words) [view diff] case mismatch in snippet view article find links to article

Semenza, Gregg L. (1999). "Regulation of Mammalian O2 Homeostasis by Hypoxia-Inducible Factor 1". Annual Review of Cell and Developmental Biology. 15 (1): 551–578

Von Hippel–Lindau disease (2,503 words) [view diff] no match in snippet view article find links to article

protein (pVHL) is involved in the regulation of a protein known as hypoxia inducible factor 1α (HIF1α). This is a subunit of a heterodimeric transcription

Kim Kyu-won (670 words) [view diff] exact match in snippet view article find links to article

Taeg Oh (2010). "Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1 alpha in tumor growth and metastasis". J Natl Cancer Inst. 102

ASPH (1,370 words) [view diff] exact match in snippet view article find links to article

PMID 24768550. Hirota K, Semenza GL (December 2005). "Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases". Biochemical and Biophysical

Nuclear receptor coactivator 2 (1,944 words) [view diff] exact match in snippet view article find links to article

transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha". Mol. Cell. Biol. 20 (1): 402–15. doi:10.1128/MCB.20.1

Metabolic regulation of hematopoiesis (3,375 words) [view diff] exact match in snippet view article find links to article

CBP/p300-interacting transactivator 2 (CITED2). Both enzymes up regulate hypoxia-inducible factor 1α (HIF1α). Under hypoxic conditions, HIF1α dimerizes with HIF1ß

Iodothyronine deiodinase (2,508 words) [view diff] exact match in snippet view article find links to article

Redout EM, Muller A, Zuidwijk MJ, Visser TJ, et al. (March 2008). "Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic

Haem carrier protein 1 (1,428 words) [view diff] no match in snippet view article find links to article

"Nitric oxide regulates the expression of heme carrier protein-1 via hypoxia inducible factor-1α stabilization". PLOS ONE. 14 (9) e0222074. Bibcode:2019PLoSO

HDAC7 (2,058 words) [view diff] exact match in snippet view article find links to article

Shibasaki F (October 2004). "Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity". The Journal of

Hexokinase II (2,542 words) [view diff] exact match in snippet view article find links to article

S2CID 45600187. Kim JW, Gao P, Liu YC, Semenza GL, Dang CV (Nov 2007). "Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial

Glycogen branching enzyme (2,835 words) [view diff] no match in snippet view article find links to article

(March 2010). "Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1". PLOS ONE. 5 (3)

Aflibercept (3,909 words) [view diff] exact match in snippet view article find links to article

vascular endothelial growth factor in the primate ovary up-regulates hypoxia-inducible factor-1alpha in the follicle and corpus luteum". Endocrinology. 149 (7):

DDX3X (1,859 words) [view diff] no match in snippet view article find links to article

et al. (March 2011). "Expression of DDX3 is directly modulated by hypoxia inducible factor-1 alpha in breast epithelial cells". PLOS ONE. 6 (3) e17563. Bibcode:2011PLoSO

Carmen Domene (556 words) [view diff] exact match in snippet view article find links to article

Christopher J. Schofield (1 July 2009). "Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases". Structure. 17 (7):

Histidine decarboxylase (2,685 words) [view diff] exact match in snippet view article find links to article

Kang IC, Um JY, Kim HM, Hong SH (April 2009). "Activation of hypoxia-inducible factor-1 regulates human histidine decarboxylase expression". Cellular

IDH2 (2,094 words) [view diff] exact match in snippet view article find links to article

D-2-hydroxyglutarate, which accumulates and leads to the inhibition of hypoxia-inducible factor 1α (HIF1α) degradation (inhibition of the HIF prolyl-hydroxylase)

VDAC2 (2,675 words) [view diff] exact match in snippet view article find links to article

MJ, Kim JY, Suk K, Park JH (May 2004). "Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial

VDAC3 (2,560 words) [view diff] exact match in snippet view article find links to article

MJ, Kim JY, Suk K, Park JH (May 2004). "Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial

Ras GTPase (4,063 words) [view diff] exact match in snippet view article find links to article

(February 2005). "Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death". Cancer Research

PSMA7 (3,229 words) [view diff] exact match in snippet view article find links to article

replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses

Evofosfamide (1,886 words) [view diff] exact match in snippet view article find links to article

nasopharyngeal carcinoma (NPC) tissues by inhibiting the overexpression of hypoxia-inducible factor-1α (HIF-1α). In this study , the efficacy of Evofosfamide along

Mir-17 microRNA precursor family (4,138 words) [view diff] exact match in snippet view article find links to article

K, Matsuyama Y, Goto H, Takahashi T (2008). "Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17-92 microRNA cluster". Cancer

Noncoding RNA Activated by DNA Damage (1,278 words) [view diff] exact match in snippet view article find links to article

vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/ hypoxia-inducible factor-1α (HIF-1α)". Bioengineered. 13 (1): 950–962. doi:10.1080/21655979

Carbonic anhydrase 9 (2,759 words) [view diff] exact match in snippet view article find links to article

the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1 alpha stabilization: a role for phosphatidylinositol 3'-kinase"

Joan Guinovart (1,450 words) [view diff] no match in snippet view article find links to article

Peso, L. (2010). "Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1". PLOS ONE. 5 (3)

Ubiquitin ligase (4,436 words) [view diff] exact match in snippet view article find links to article

recognition part of a specific E3 ligase), for instance, recognizes the hypoxia-inducible factor alpha (HIF-α) only under normal oxygen conditions, when its proline

Steven McKnight (2,902 words) [view diff] no match in snippet view article find links to article

In the late 1990s, McKnight identified the transcription factor hypoxia inducible factor 2alpha (HIF2alpha, a member of the bHLH family) and the prolyl

NDRG1 (2,251 words) [view diff] exact match in snippet view article find links to article

dependent and independent manner. Under hypoxia the oxygen sensor hypoxia-inducible factor (HIF)-1α is translocated from cytoplasma to nucleus, where binds

Mdm2 (4,017 words) [view diff] exact match in snippet view article find links to article

"Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha". Genes & Development. 14 (1): 34–44. doi:10.1101/gad.14

Carrie L. Partch (2,045 words) [view diff] no match in snippet view article find links to article

2011). "Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B". Proceedings of the

VDAC1 (4,278 words) [view diff] exact match in snippet view article find links to article

MJ, Kim JY, Suk K, Park JH (May 2004). "Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial

KRBA1 (1,274 words) [view diff] no match in snippet view article find links to article

part of protein complex known as E3 ubiquitin ligase and targets hypoxia-inducible-factor 1a (HIF-1a) for breakdown. It is reported that there is a new protein

Itaconic acid (10,220 words) [view diff] exact match in snippet view article find links to article

tumor necrosis factor; b) inhibits its target genes expression of hypoxia-inducible factor 1-alpha which is converted enzymatically to an active form that

The Hallmarks of Cancer (4,312 words) [view diff] exact match in snippet view article find links to article

hypoxia, or oxygen deprivation in the tumor core, which stabilizes hypoxia-inducible factor-1α (HIF-1α), a transcription factor that promotes the production

G-quadruplex (12,083 words) [view diff] no match in snippet view article find links to article

which was tested using the G-quadruplex-binding ligand 360A. Hypoxia inducible factor 1ɑ, HIF-1ɑ, remains involved in cancer signaling through its binding

GLUT1 (3,387 words) [view diff] no match in snippet view article find links to article

Richardson S, Mobasheri R, Shakibaei M, Hoyland JA (October 2005). "Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative

DLC1 (3,161 words) [view diff] no match in snippet view article find links to article

epidermal growth factor receptor (EGFR)-MAP/ERK Kinase (MEK)- hypoxia inducible factor 1 (HIF1) pathway. DLC1 expression is downregulated by both promoter

Gene expression (10,192 words) [view diff] no match in snippet view article find links to article

S2CID 20241963. Song Y, Wang W, Qu X, Sun S (February 2009). "Effects of hypoxia inducible factor-1alpha (HIF-1alpha) on the growth & adhesion in tongue squamous

Reactive oxygen species (8,465 words) [view diff] exact match in snippet view article find links to article

of activated B cells (NF-κB), activator protein-1 (AP-1), hypoxia-inducible factor-1α and signal transducer and activator of transcription 3 (STAT3)

Mark Cushman (2,836 words) [view diff] exact match in snippet view article find links to article

estrogen receptor, vascular endothelial growth factor-2 (VEGFR-2), hypoxia-inducible factor 1-alpha (HIF-1a), tyrosyl DNA phosphodiesterases (TDP) 1 and 2

Epithelial–mesenchymal transition (6,880 words) [view diff] exact match in snippet view article find links to article

induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma". BMC Cancer. 13: 108. doi:10

Pheochromocytoma (17,748 words) [view diff] exact match in snippet view article find links to article

pheochromocytoma-associated susceptibility genes: Pacak–Zhuang Syndrome Hypoxia-inducible factor 2 alpha (HIF2A) Polycythemia Duodenal somatostatinoma Retinal and

Nickel (10,168 words) [view diff] exact match in snippet view article find links to article

people." Reports show that both the nickel-induced activation of hypoxia-inducible factor (HIF-1) and the up-regulation of hypoxia-inducible genes are caused

Anti-allergic agent (2,411 words) [view diff] case mismatch in snippet view article find links to article

"Homeostatic Regulation of Glucocorticoid Receptor Activity by Hypoxia-Inducible Factor 1: From Physiology to Clinic". Cells. 10 (12): 3441. doi:10.3390/cells10123441

GPATCH2L (1,905 words) [view diff] no match in snippet view article find links to article

Signal transducer and activator of transcription 0.896 2 HIFF Hypoxia inducible factor, bHLH/PAS protein family 0.989 5 HESF Vertebrate homologues of

CUNY Graduate Center (7,146 words) [view diff] exact match in snippet view article find links to article

Biology Initiative, was instrumental in the identification of hypoxia-inducible factor 2-alpha (HIF-2α) as a druggable target and the drug development

Craniofacial regeneration (4,367 words) [view diff] exact match in snippet view article find links to article

C, Deng L, Liu X, Cao X, Gilbert SR, et al. (June 2007). "The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal

Neurobiological effects of physical exercise (10,339 words) [view diff] exact match in snippet view article find links to article

has been associated with increased expression and activation of hypoxia-inducible factor 1 alpha (HIF-1α), heat shock proteins, and brain-derived neurotrophic

Neurobiological effects of physical exercise (10,339 words) [view diff] exact match in snippet view article find links to article

has been associated with increased expression and activation of hypoxia-inducible factor 1 alpha (HIF-1α), heat shock proteins, and brain-derived neurotrophic

Renal cell carcinoma (11,134 words) [view diff] exact match in snippet view article find links to article

immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins". Modern Pathology. 24 (9): 1207–20. doi:10

Skeletal muscle (13,856 words) [view diff] exact match in snippet view article find links to article

composed of members of the Six protein family. Moreover, the hypoxia-inducible factor 1-α (HIF1A) has been identified as a master regulator for the expression

MTORC1 (7,816 words) [view diff] no match in snippet view article find links to article

the inhibition of protein synthesis. Under hypoxic conditions, hypoxia inducible factor one alpha (HIF1A) will stabilize and activate transcription of

MTOR (12,710 words) [view diff] exact match in snippet view article find links to article

PMID 21157483. Thomas GV, Tran C, Mellinghoff IK, et al. (January 2006). "Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer"

Folliculin (5,618 words) [view diff] exact match in snippet view article find links to article

of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility".

Hyperbaric medicine (8,963 words) [view diff] exact match in snippet view article find links to article

therapy promotes neurogenesis through reactive oxygen species/hypoxia-inducible factor-1α/β-catenin pathway in middle cerebral artery occlusion rats"

Oxythiamine (4,185 words) [view diff] exact match in snippet view article find links to article

signaling molecule, influencing both epigenetic enzymes and the hypoxia-inducible factor HIF-1α. Elevated α-ketoglutarate levels may promote HIF hydroxylase

CSNK1D (14,746 words) [view diff] exact match in snippet view article find links to article

E, Simos G (September 2010). "Casein kinase 1 regulates human hypoxia-inducible factor HIF-1". Journal of Cell Science. 123 (Pt 17): 2976–86. doi:10.1242/jcs