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searching for Humanized mouse 16 found (22 total)

Severe combined immunodeficient mice (1,209 words) [view diff] exact match in snippet view article find links to article

acquired immunodeficiency syndrome (AIDS) over time. Furthermore, humanized mouse models can also be used to test potential therapies for this disease

FCGR2A (1,120 words) [view diff] exact match in snippet view article find links to article

1006/clim.2000.4955. ISSN 1521-6616. PMID 11141335. McKenzie SE (2002). "Humanized mouse models of FcR clearance in immune platelet disorders". Blood Rev. 16

BZLF1 (518 words) [view diff] case mismatch in snippet view article find links to article

Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential. Journal of Virology. Volume 91. Issue

HIV capsid inhibition (1,418 words) [view diff] exact match in snippet view article find links to article

long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model". Nature Medicine. 25 (9): 1377–1384. doi:10.1038/s41591-019-0560-x

Pembrolizumab (7,695 words) [view diff] exact match in snippet view article find links to article

human PD-1 receptor, a humanized mouse monoclonal [228-L-proline(H10-S>P)]γ4 heavy chain (134-218') disulfide and a humanized mouse monoclonal κ light chain

TOL101 (768 words) [view diff] exact match in snippet view article find links to article

induction. Examination of the ability of TOL101 to modulate T cells in a humanized mouse model not only confirmed these in vitro results but also suggested

Todd M. Allen (854 words) [view diff] exact match in snippet view article find links to article

published over 180 peer-reviewed papers on HIV and HCV. His work used humanized mouse models to accelerate development and testing of novel immunotherapies

CYP2D6 (3,949 words) [view diff] exact match in snippet view article find links to article

Idle JR, Gonzalez FJ (May 2004). "Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates". Drug Metabolism Reviews. 36 (2):

MRN complex (3,079 words) [view diff] exact match in snippet view article find links to article

2005). "Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models". Nature Cell Biology. 7 (7): 675–85. doi:10.1038/ncb1270. PMID 15965469

FOXP2 (5,881 words) [view diff] exact match in snippet view article find links to article

comparison to knockout mice with one non-functional copy of FOXP2, the humanized mouse model showed opposite effects when testing its effect on the levels

Angiotensin-converting enzyme 2 (5,225 words) [view diff] exact match in snippet view article find links to article

human lung cell lines and prevent SARS-CoV-2 induced ARDS in an ACE2 humanized mouse model. Infused rhACE2 has been evaluated in clinical trials for the

Mighty Mouse (5,027 words) [view diff] exact match in snippet view article find links to article

flash as Super Mouse! He's no longer a tiny rodent, but a two-footed, humanized mouse with a massive chest and powerful biceps. His costume is like Superman's

Park Seong-hoe (1,640 words) [view diff] exact match in snippet view article find links to article

207:237-246, 2010). Based on this theory, he subsequently established humanized mouse system in which human T cells can develop via T cell-T cell interaction

Facundo D. Batista (1,593 words) [view diff] exact match in snippet view article find links to article

1856-1871.e6. doi: 10.1016/j.immuni.2022.07.020 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies

Moriya Tsuji (2,096 words) [view diff] exact match in snippet view article find links to article

vaccine development. Tsuji's team has also succeeded in establishing a humanized mouse model that mimics the human immune system, called HIS mice. He used

2024 in science (27,396 words) [view diff] exact match in snippet view article find links to article

Patrick S.; Xu, Zhenming; Zan, Hong; Casali, Paolo (August 2024). "A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody