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Longer titles found: Acid dissociation constant (view), Equilibrium dissociation constant (view)

searching for Dissociation constant 71 found (270 total)

2,2,6,6-Tetramethylpiperidine (246 words) [view diff] exact match in snippet view article find links to article

pKaH (conjugate acid dissociation constant, a measure of basicity) is 11.07 at 25 °C, while its pKa (acid dissociation constant, a measure of acidity)

Tellurol (348 words) [view diff] exact match in snippet view article find links to article

acidity and dissociation constant of hydrogen telluride, H2Te, which has a (first) pKa of 2.64 corresponding to a dissociation constant of 2.3 × 10−3

Isoionic point (445 words) [view diff] exact match in snippet view article find links to article

first acid dissociation constant K 2 = {\displaystyle K_{2}=} second acid dissociation constant K w = {\displaystyle K_{w}=} dissociation constant for water

P50 (pressure) (586 words) [view diff] exact match in snippet view article

reversible reaction below, whose equilibrium constant K (which is also a dissociation constant, since it describes a reversible association-dissociation event)

BAPTA (284 words) [view diff] exact match in snippet view article find links to article

similarly to EGTA and EDTA. There is a range of reported values for the dissociation constant of BAPTA, though 0.2 μM appears consistently. The rate constant

Emilian Bratu (385 words) [view diff] exact match in snippet view article find links to article

With the Austrian physical chemist Otto Redlich, he studied the dissociation constant of heavy water. Born in Bucharest, he studied at the Saint Sava

1-(3-Chlorophenyl)-4-(2-phenylethyl)piperazine (354 words) [view diff] exact match in snippet view article

reported to date. It is highly selective for the dopamine transporter (dissociation constant Ki = 0.04 nM) with relatively low affinity for the closely related

Thymol (2,331 words) [view diff] exact match in snippet view article find links to article

alkaline aqueous solutions due to deprotonation of the phenol. Its dissociation constant (pKa) is 10.59±0.10. Thymol absorbs maximum UV radiation at 274 nm

Bromous acid (1,057 words) [view diff] exact match in snippet view article find links to article

(VI): 2 MnO− 4 + BrO− 2 + OH− → 2 MnO2− 4 + BrO− 3 + H2O The acid dissociation constant of bromous acid, Ka = ⁠[H+][BrO− 2]/[HBrO2]⁠, was determined using

Lineweaver–Burk plot (1,032 words) [view diff] exact match in snippet view article find links to article

M. T. (1979-12-10). "Evaluation of methods for estimating the dissociation constant of tight binding enzyme inhibitors". The Journal of Biological Chemistry

Competitive inhibition (2,864 words) [view diff] exact match in snippet view article find links to article

to the binding site is decreased (the K d {\displaystyle K_{d}} dissociation constant is apparently increased). The change in K m {\displaystyle K_{m}}

Thyroid function tests (3,677 words) [view diff] exact match in snippet view article find links to article

Clearance exponent for T4 (1.1e-6 sec−1) K41: Dissociation constant T4-TBG (2e10 L/mol) K42: Dissociation constant T4-TBPA (2e8 L/mol) DT: EC50 for TSH (2.75

Otenzepad (110 words) [view diff] exact match in snippet view article find links to article

Potency of Otenzepad at muscarinic receptor isoforms mAChR isoform Dissociation constant (Ki) M1 537.0 - 1300nM M2 81.0 - 186nM M3 838 - 2089.0nM M4 407

Molar conductivity (1,376 words) [view diff] exact match in snippet view article find links to article

hydration in solution. Ostwald's law of dilution, which gives the dissociation constant of a weak electrolyte as a function of concentration, can be written

Draculin (1,010 words) [view diff] exact match in snippet view article find links to article

characterized by the forward reaction rate constant k2 = 0.072 sec-1. The dissociation constant is determined as the ratio k-1/k1 = 13.76 nM. Because of the immediate

Sulfide (1,076 words) [view diff] exact match in snippet view article find links to article

PMID 29404555. Meyer, B; Ward, K; Koshlap, K; Peter, L (1983). "Second dissociation constant of hydrogen sulfide". Inorganic Chemistry. 22 (16): 2345. doi:10

Cooperative binding (5,539 words) [view diff] exact match in snippet view article find links to article

{\displaystyle K^{*}} is an empirical dissociation constant, and K d {\displaystyle K_{d}} a microscopic dissociation constant (used in modern forms of the equation

Monohydrogen phosphate (230 words) [view diff] exact match in snippet view article find links to article

Equilibrium Dissociation constant, pKa H3PO4 ⇌ H 2PO− 4 + H+ pKa1 = 2.14 H 2PO− 4 ⇌ HPO2− 4 + H+ pKa2 = 7.20 HPO2− 4 ⇌ PO3− 4 + H+ pKa3 = 12.37

Thioenol (129 words) [view diff] exact match in snippet view article find links to article

Popik, Vladimir V.; Rappoport, Zvi; Selzer, Tzvia (1998). "The acid dissociation constant of triphenylethenethiol, a simple thioenol, and that of its oxygen–enol

Carbamino (646 words) [view diff] exact match in snippet view article find links to article

normal adult and fetal blood. In adult red cells, the first apparent dissociation constant of carbonic acid is significantly higher in oxygenated (-log10K'1

Copper monosulfide (1,247 words) [view diff] exact match in snippet view article find links to article

Covellite Rollie J. Myers (1986). "The new low value for the second dissociation constant for H2S: Its history, its best value, and its impact on the teaching

Drug action (871 words) [view diff] exact match in snippet view article find links to article

will also be less. This can be measured numerically by using the dissociation constant KD. The value of KD is the same as the concentration of drug when

Janus kinase 3 (5,166 words) [view diff] exact match in snippet view article find links to article

parameters showed that phosphorylated (P) Jak3 binds to P-villin with a dissociation constant (Kd) of 23 nM and a Hill's coefficient of 3.7. Pairwise binding

Streptokinase (1,615 words) [view diff] exact match in snippet view article find links to article

the Ile1 substitutions, the Lys698 mutations also decreased the dissociation constant of the streptokinase complex by 15 to 50 fold. These observations

Haber–Weiss reaction (802 words) [view diff] exact match in snippet view article find links to article

Rabani, Joseph; Dorfman, Leon M.; Schwarz, Harold A. (1970). "Acid dissociation constant and decay kinetics of the perhydroxyl radical". The Journal of Physical

Mefway (18F) (937 words) [view diff] exact match in snippet view article

ratios compared to fcway(18F) The ability to separately measure dissociation constant, KD and receptor density Bmax has been shown to be of potential

Cinnabar (2,257 words) [view diff] exact match in snippet view article find links to article

S2CID 235729616. Myers, R. J. (1986). "The new low value for the second dissociation constant of H2S. Its history, its best value, and its impact on teaching

EF hand (2,077 words) [view diff] exact match in snippet view article find links to article

hands have very high selectivity for calcium. For example, the dissociation constant of alpha parvalbumin for Ca2+ is ~1000 times lower than that for

Zinc dithiophosphate (1,002 words) [view diff] exact match in snippet view article find links to article

organic solvents this monomeric compound exists mainly as dimer. The dissociation constant for the dimers at room temperature is 10-2 M [Zn[(S2P(OR)2]2]2 ⇌

Phosphate (2,540 words) [view diff] exact match in snippet view article find links to article

Equilibrium Dissociation constant Ka pKa H3PO4 ⇌ H2PO−4 + H+ K a 1 = [ H + ] [ H 2 PO 4 − ] [ H 3 PO 4 ] ≈ 7.5 × 10 − 3 {\displaystyle K_{a1}={\frac {[{\ce

Dean Burk (817 words) [view diff] exact match in snippet view article find links to article

1021/ja01318a036.. Lineweaver H, Burk D, Deming, W E (1934). "The dissociation constant of nitrogen-nitrogenase in Azobacter". Journal of the American Chemical

Reslizumab (1,383 words) [view diff] exact match in snippet view article find links to article

correlate with asthma severity. Reslizumab binds to IL-5 with a dissociation constant of 81 pM and inhibiting IL-5 signaling, which reduces the production

Acetylcholinesterase inhibitor (2,462 words) [view diff] exact match in snippet view article find links to article

interval after mixing of the cholinesterase and the TEPP, KI is the dissociation constant for cholinesterase-TEPP complex (E–PX) and I is the TEPP concentration

CD80 (2,435 words) [view diff] exact match in snippet view article find links to article

T-cell activation as well as reduction of cytokine production. Its dissociation constant with CD80 is between the CD28 and CTLA-40 (Kd = 1.4 μM). The complicated

Ribosomal protein SA (2,584 words) [view diff] exact match in snippet view article find links to article

effects. EGCG binds only to the N-domain of RPSA in vitro, with a dissociation constant of 100 nM, but not to its C-domain. GRCh38: Ensembl release 89:

Glucose-6-phosphate dehydrogenase (2,413 words) [view diff] exact match in snippet view article find links to article

severe class I mutations, G488S and G488V, drastically increase the dissociation constant between NADP+ and the structural site by a factor of 7 to 13. With

Angelic acid (833 words) [view diff] exact match in snippet view article find links to article

isomer, angelic acid has a lower melting point and higher acid dissociation constant than tiglic acid, in accordance to usually observed trends. Angelic

Hydrothermal synthesis (1,905 words) [view diff] exact match in snippet view article find links to article

reduced, allowing nonpolar substances to better dissolve. The self-dissociation constant of water also increases by three orders of magnitude, making OH-

Phenformin (939 words) [view diff] exact match in snippet view article find links to article

higher affinity for mitochondrial membranes than metformin. Its dissociation constant (pKa) is 2.7, 11.8 (at 32 °C), and log P = –0.8.[citation needed]

Dicyclopentadiene (1,088 words) [view diff] exact match in snippet view article find links to article

cyclopentadiene monomer starts to become thermodynamically favored (the dissociation constant Kd = [cyclopentadiene]2 / [dicyclopentadiene] > 1). For instance

Pepsin (3,450 words) [view diff] exact match in snippet view article find links to article

potently inhibitor specific for acid proteases with an inhibitory dissociation constant (Ki) of about 10−10 M for pepsin. The statyl residue of pepstatin

Phosphatidic acid (3,086 words) [view diff] exact match in snippet view article find links to article

activated by local association with PLD and production of PA. The dissociation constant of PA for TREK-1 is approximately 10 micromolar. The relatively

Olfactory receptor (4,261 words) [view diff] exact match in snippet view article find links to article

D2O; melting points: 0.0 °C for H2O, 3.82 °C for D2O), pKa (i.e., dissociation constant: 9.71x10−15 for H2O vs. 1.95x10−15 for D2O, cf. heavy water) and

Affinity electrophoresis (2,124 words) [view diff] exact match in snippet view article find links to article

the complex during the experiment can be used to calculate the dissociation constant of the complex. Dynamic equilibrium ACE involves the combination

Protein S (Myxococcus xanthus) (746 words) [view diff] exact match in snippet view article

S binds two 2 mol of calcium per mol of protein with a binding dissociation constant of 27 and 76 μM according to dialysis experiments. In the same study

Hans Lineweaver (1,047 words) [view diff] exact match in snippet view article find links to article

1021/ja01318a036. Lineweaver H, Burk D, Deming, W E (1934). "The dissociation constant of nitrogen-nitrogenase in Azobacter". Journal of the American Chemical

Lipid-gated ion channels (1,928 words) [view diff] exact match in snippet view article find links to article

Comoglio et al was experimentally confirmed when it was shown that the dissociation constant of PA for TREK-1 is 10 micro molar, a Kd much weaker than the bulk

Oncostatin M (4,317 words) [view diff] exact match in snippet view article find links to article

two receptor species, a high affinity form with an approximate dissociation constant Kd of 1-10 pM, and a low affinity form of 0.4-1 nM. Subsequently

NMDA receptor antagonist (4,196 words) [view diff] exact match in snippet view article find links to article

L-Phenylalanine. a naturally occurring amino acid (equilibrium dissociation constant (KB) from Schild regression is 573 μM). Xenon: an anesthetic. List

Altitude sickness (4,847 words) [view diff] exact match in snippet view article find links to article

haemoconcentration and erythrogenesis. Alkalosis shifts the haemoglobin dissociation constant to the left, 2,3-BPG increases to counter this. Cardiac output increases

James Inglese (1,302 words) [view diff] case mismatch in snippet view article find links to article

Adduct Inhibitor of a Purine Biosynthetic Enzyme with a Picomolar Dissociation Constant". J. Med. Chem. 32 (5): 937–940. doi:10.1021/jm00125a002. PMID 2709379

W. Edwards Deming (6,128 words) [view diff] exact match in snippet view article find links to article

Press. pp. 60–74. Lineweaver H, Burk D, Deming, W E (1934). "The dissociation constant of nitrogen-nitrogenase in Azobacter". J. Amer. Chem. Soc. 56: 225–230

Debye–Hückel theory (7,543 words) [view diff] exact match in snippet view article find links to article

one that is not fully dissociated. As such it has a dissociation constant. The dissociation constant can be used to calculate the extent of dissociation

Neosaxitoxin (5,274 words) [view diff] exact match in snippet view article find links to article

drugs NSTX and other site 1 blockers have high affinity (very low dissociation constant) and high specificity for Nav channels. The action of NSTX produces

CII protein (1,610 words) [view diff] exact match in snippet view article find links to article

magnitude less strongly than the lambda repressor cI (3), and has a dissociation constant of ~80nM. DNA binding is achieved using the common helix-turn-helix

Clinical neurochemistry (2,611 words) [view diff] exact match in snippet view article find links to article

utilizes the Michaelis–Menten equation to describe drug affinity (dissociation constant Kd) and total binding (Bmax). Although Kd and Bmax can be determined

Copper naphthenate (1,755 words) [view diff] exact match in snippet view article find links to article

of dissociated salt present is dependent on the pH and pKa (the dissociation constant). The degree of dissociation influences the behavior of the substance

Olanzapine (8,989 words) [view diff] exact match in snippet view article find links to article

therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the

Bafilomycin (4,672 words) [view diff] exact match in snippet view article find links to article

interaction between bafilomycin and V-ATPase is not covalent, its low dissociation constant of about 10 nM describes the strength of its interaction and can

Metformin (14,940 words) [view diff] exact match in snippet view article find links to article

Steady state is usually reached in 1–2 days. Metformin has acid dissociation constant values (pKa) of 2.8 and 11.5, so it exists very largely as the hydrophilic

Radioligand (4,347 words) [view diff] exact match in snippet view article find links to article

Depiction of a Scatchard plot with relation to number of binding sites, Bmax, and equilibrium dissociation constant Kd.

Surface plasmon resonance microscopy (7,726 words) [view diff] exact match in snippet view article find links to article

injections of thrombin at different concentrations. Solution phase dissociation constant KDsol (3.16 ± 1.16 nM) is calculated from the measured concentrations

Anti-thrombin aptamers (2,660 words) [view diff] exact match in snippet view article find links to article

TBA shows good affinity and specificity against thrombin. The dissociation constant of TBA-thrombin has been reported in nano-molar range, and TBA does

Urine test strip (6,376 words) [view diff] exact match in snippet view article find links to article

test strip test for specific gravity is based on the change in dissociation constant (pKa) of an anionic polyelectrolyte (poly-(methyl vinyl ether/maleic

Sarafotoxin (2,689 words) [view diff] exact match in snippet view article find links to article

a maximum binding capacity of 110 fmol per mg of protein and a dissociation constant (KD) of 3–5 nM. SRTX-a, SRTX-b and STRX-c inhibit binding of iodinated

Fluorescent glucose biosensor (7,448 words) [view diff] exact match in snippet view article find links to article

generated a Badan-labelled Ggbp mutant (H152C/A213R/L238S), with a dissociation constant in the human physiological glucose range (Km=11mM) and a twofold

Intracellular delivery (8,788 words) [view diff] exact match in snippet view article find links to article

key component of lipid nanoparticle formulations, with an acid dissociation constant (pKa) close to the early endosomal pH enable endosomal release into

Glass bead road surface marking (2,420 words) [view diff] exact match in snippet view article find links to article

under high pH as HAsO 4 2 − {\displaystyle {\ce {HAsO4^2-}}} . Dissociation constant: See Arsenic Acid properties. The predominant lead species leaches

Nucleoid (17,312 words) [view diff] exact match in snippet view article find links to article

coli cell to be 2 μm3. 1 Binding affinity refers to equilibrium dissociation constant (Kd) in molar units (M). ND = not determined Histone-like protein

Pharmacodynamics of estradiol (12,043 words) [view diff] exact match in snippet view article find links to article

characteristically exhibit high affinity for estradiol-17J3, with an equilibrium dissociation constant of 0.1 nM. The number of these sites in target tissues is generally

PH-responsive tumor-targeted drug delivery (3,083 words) [view diff] exact match in snippet view article find links to article

imidazolyl. Depending on the introduced functional group's acid dissociation constant (pKa), drug release from these nanocarriers can occur through precipitation