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Longer titles found: Phosphatidic acid phosphatase 2c (view), Lysophosphatidic acid (view), Lysophosphatidic acid phosphatase type 6 (view)

searching for Phosphatidic acid 80 found (160 total)

alternate case: phosphatidic acid

PX domain (355 words) [view diff] exact match in snippet view article find links to article

interact primarily with PtdIns(3)P lipids. However some of them bind to phosphatidic acid, PtdIns(3,4)P2, PtdIns(3,5)P2, PtdIns(4,5)P2, and PtdIns(3,4,5)P3

DGKD (621 words) [view diff] exact match in snippet view article find links to article

that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in

PPAPDC1A (135 words) [view diff] exact match in snippet view article find links to article

Phosphatidate phosphatase PPAPDC1A also known as phosphatidic acid phosphatase type 2 domain containing 1A is an enzyme that in humans is encoded by the

LIPH (gene) (520 words) [view diff] exact match in snippet view article

Bandoh K, Nagai Y, Taguchi R, Inoue K, Arai H (Sep 2002). "A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid". J

Beta-galactoside permease (468 words) [view diff] no match in snippet view article find links to article

Galactoside permease is a protein coded by the lacY gene of the lac operon, and is found bound to the membrane of a cell for the purpose of binding galactoside

Phosphatidate cytidylyltransferase (368 words) [view diff] exact match in snippet view article find links to article

diphosphoglyceride pyrophosphorylase, phosphatidate cytidyltransferase, phosphatidic acid cytidylyltransferase, CTP:1,2-diacylglycerophosphate-cytidyl transferase

Phospholipid transfer protein (1,032 words) [view diff] exact match in snippet view article find links to article

binding phosphatidic acid binding ceramide binding phosphatidylglycerol binding phosphatidylethanolamine transfer activity phosphatidic acid transfer

Phosphatidylinositol transfer protein, cytoplasmic 1 (298 words) [view diff] exact match in snippet view article find links to article

"Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid". J. Biol. Chem. 287 (38): 32263–76. doi:10.1074/jbc.M112.375840.

DGKZ (929 words) [view diff] exact match in snippet view article find links to article

mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid". J. Biol. Chem. 280 (11): 10091–9. doi:10.1074/jbc.M412296200. PMID 15632115

LPIN1 (1,082 words) [view diff] exact match in snippet view article find links to article

controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1". The Journal of Biological Chemistry. 282 (1):

PLA2G2A (901 words) [view diff] exact match in snippet view article find links to article

extracellular region plasma membrane extracellular space Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling positive

CDP-diacylglycerol—inositol 3-phosphatidyltransferase (287 words) [view diff] exact match in snippet view article find links to article

PMID 41587. Prottey C, Hawthorne JN (1967). "The biosynthesis of phosphatidic acid and phosphatidylinositol in mammalian pancreas". Biochem. J. 105 (1):

ABHD5 (934 words) [view diff] exact match in snippet view article find links to article

Cellular component lipid droplet cytoplasm cytosol Biological process phosphatidic acid biosynthetic process cell differentiation lipid metabolism fatty acid

ALPI (1,168 words) [view diff] exact match in snippet view article find links to article

extracellular region plasma membrane Biological process metabolism dephosphorylation phosphatidic acid biosynthetic process digestion Sources:Amigo / QuickGO

ATP13A2 (712 words) [view diff] exact match in snippet view article find links to article

protein binding hydrolase activity ATP binding cupric ion binding phosphatidic acid binding zinc ion binding phosphatidylinositol-3,5-bisphosphate binding

PDE4A (1,356 words) [view diff] exact match in snippet view article find links to article

Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid" (PDF). The Journal of Biological Chemistry. 277 (31): 28298–309.

MARK1 (957 words) [view diff] exact match in snippet view article find links to article

activity phosphatidylserine binding metal ion binding kinase activity phosphatidic acid binding protein serine/threonine kinase activity tau-protein kinase

SESTD1 (322 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function phosphatidic acid binding phosphatidylinositol-4-phosphate binding phosphatidylinositol-5-phosphate binding phosphatidylinositol-4

Long-chain fatty acid transport protein 1 (598 words) [view diff] exact match in snippet view article find links to article

cytosol integral component of plasma membrane Biological process phosphatidic acid biosynthetic process phosphatidylserine biosynthetic process lipid

Nicolas Bazan (4,361 words) [view diff] exact match in snippet view article find links to article

is introduced to a large extent through the de novo synthesis of phosphatidic acid. His laboratory later identified an activating enzyme for docosahexaenoic

Mechanosensation (3,004 words) [view diff] exact match in snippet view article find links to article

biological membrane was directly attributed to the generation of phosphatidic acid in a fast two step process (<3 ms). Activation was based on a model

RAPGEF6 (416 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function phosphatidic acid binding GTP-dependent protein binding protein binding guanyl-nucleotide exchange factor activity Cellular

PLA2G12A (469 words) [view diff] exact match in snippet view article find links to article

structure extracellular region endoplasmic reticulum Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling

PLA2G4B (594 words) [view diff] exact match in snippet view article find links to article

region mitochondrion mitochondrial inner membrane Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling

Plant defensin (3,922 words) [view diff] exact match in snippet view article find links to article

fungi surfaces. These include sphingolipids, glucosyceramide, and phosphatidic acid Apart from their capacity to attack and damage fungal membranes, these

LPCAT1 (149 words) [view diff] exact match in snippet view article find links to article

acyl-chain remodeling positive regulation of protein catabolic process phosphatidic acid biosynthetic process metabolism surfactant homeostasis negative regulation

MICALL1 (489 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function metal ion binding phosphatidic acid binding protein binding identical protein binding cadherin binding Cellular component

DGKQ (575 words) [view diff] exact match in snippet view article find links to article

metabolic process lipid phosphorylation regulation of gluconeogenesis phosphatidic acid biosynthetic process activation of transmembrane receptor protein

RAB3A (1,256 words) [view diff] exact match in snippet view article find links to article

S2CID 15162326. Jung YJ, Lee TH, Lee JY, Kim JH, Park JB (1999). "Phosphatidic acid is important to the translocation of Rab3A from the cytosol to phospholipid

PLA2G2D (695 words) [view diff] exact match in snippet view article find links to article

activity Cellular component extracellular region Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling

PLCD3 (862 words) [view diff] exact match in snippet view article find links to article

with high specificity to phosphatidylinositol 4,5-bisphosphate and phosphatidic acid in bilayer membranes". European Journal of Biochemistry. 262 (2):

Acylglycerol kinase (173 words) [view diff] exact match in snippet view article find links to article

PMID 14486486. Pieringer RA, Kunnes RS (July 1965). "The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in Escherichia

Amphipathic lipid packing sensor motifs (362 words) [view diff] exact match in snippet view article find links to article

Antonny B (2014). "Interaction of the Spo20 membrane-sensor motif with phosphatidic acid and other anionic lipids, and influence of the membrane environment"

GPAM (593 words) [view diff] exact match in snippet view article find links to article

proliferation lipid metabolism glycerophospholipid metabolic process phosphatidic acid biosynthetic process metabolism negative regulation of activation-induced

Lysocardiolipin acyltransferase 1 (115 words) [view diff] exact match in snippet view article find links to article

membrane membrane endoplasmic reticulum cytosol Biological process phosphatidic acid biosynthetic process multicellular organism development CDP-diacylglycerol

Dynamin-like 120 kDa protein (1,957 words) [view diff] exact match in snippet view article find links to article

activity magnesium ion binding microtubule binding GTPase activity phosphatidic acid binding cardiolipin binding lipid binding kinase binding Cellular

KCNK2 (1,429 words) [view diff] exact match in snippet view article find links to article

enzyme and the channel traffic to PIP2 domains where the enzyme makes phosphatidic acid that opens the channel. Tandem pore domain potassium channel GRCh38:

SOBER1 (338 words) [view diff] exact match in snippet view article find links to article

Mudgett MB (December 2009). "SOBER1 phospholipase activity suppresses phosphatidic acid accumulation and plant immunity in response to bacterial effector

PLA2G4A (1,021 words) [view diff] exact match in snippet view article find links to article

remodeling cellular response to antibiotic lipid catabolic process phosphatidic acid biosynthetic process phosphatidylcholine acyl-chain remodeling metabolism

Neurogranin (781 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function phosphatidic acid binding phosphatidylinositol-3,4,5-trisphosphate binding calmodulin binding Cellular component cytoplasm

PNPLA3 (815 words) [view diff] exact match in snippet view article find links to article

fatty acid metabolic process glycerophospholipid metabolic process phosphatidic acid biosynthetic process lipid droplet organization phospholipid biosynthetic

PLA2G10 (809 words) [view diff] exact match in snippet view article find links to article

component extracellular region extracellular space Biological process phosphatidic acid biosynthetic process positive regulation of protein metabolic process

PLA2G1B (881 words) [view diff] exact match in snippet view article find links to article

region cell surface extracellular space cytosol Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling intracellular

MAPKAP1 (796 words) [view diff] exact match in snippet view article find links to article

5-bisphosphate binding phosphatidylinositol-3,4-bisphosphate binding phosphatidic acid binding protein binding phosphatidylinositol-4,5-bisphosphate binding

RAPGEF2 (867 words) [view diff] exact match in snippet view article find links to article

activity guanyl-nucleotide exchange factor activity WW domain binding phosphatidic acid binding PDZ domain binding cAMP binding cGMP binding beta-1 adrenergic

PITPNM1 (949 words) [view diff] exact match in snippet view article find links to article

activity phosphatidylcholine binding phosphatidylinositol binding phosphatidic acid binding phospholipid transporter activity calcium ion binding receptor

COMMD1 (892 words) [view diff] exact match in snippet view article find links to article

binding metal ion binding phosphatidylinositol-3,4-bisphosphate binding phosphatidic acid binding protein binding identical protein binding phosphatidylinositol-4

RAPGEF2 (867 words) [view diff] exact match in snippet view article find links to article

activity guanyl-nucleotide exchange factor activity WW domain binding phosphatidic acid binding PDZ domain binding cAMP binding cGMP binding beta-1 adrenergic

COMMD1 (892 words) [view diff] exact match in snippet view article find links to article

binding metal ion binding phosphatidylinositol-3,4-bisphosphate binding phosphatidic acid binding protein binding identical protein binding phosphatidylinositol-4

PLCD1 (904 words) [view diff] exact match in snippet view article find links to article

phosphatidylserine binding signal transducer activity metal ion binding phosphatidic acid binding phosphoric diester hydrolase activity phospholipase C activity

Oxysterol-binding protein (2,071 words) [view diff] exact match in snippet view article find links to article

Oxysterol-binding protein homolog 4 434 lipid binding oxysterol binding phosphatidic acid binding phosphatidylinositol-4,5-bisphosphate binding

Congenital hypoplastic anemia (2,325 words) [view diff] exact match in snippet view article find links to article

chronic multifocal osteomyelitis, and neutrophilic dermatosis. The phosphatidic acid phosphatase gene, LPIN2, is mutated in the disease, which is an autosomal

Farnesoid X receptor (1,979 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II positive regulation of phosphatidic acid biosynthetic process cholesterol homeostasis lipid metabolism multicellular

PPP1CC (1,210 words) [view diff] exact match in snippet view article find links to article

YA (2002). "Tight binding inhibition of protein phosphatase-1 by phosphatidic acid. Specificity of inhibition by the phospholipid". J. Biol. Chem. 277

PLA2G5 (937 words) [view diff] exact match in snippet view article find links to article

region perinuclear region of cytoplasm cell surface Biological process phosphatidic acid biosynthetic process response to cytokine phosphatidylserine acyl-chain

PTPN6 (2,292 words) [view diff] exact match in snippet view article find links to article

phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C". J. Biol. Chem. 270

Sphingosine kinase 1 (1,155 words) [view diff] case mismatch in snippet view article find links to article

NT (2004). "Sphingosine Kinase 1 Is an Intracellular Effector of Phosphatidic Acid". The Journal of Biological Chemistry. 279 (43): 44763–44774. doi:10

PKC alpha (2,643 words) [view diff] exact match in snippet view article find links to article

membrane and is responsible for hydrolyzing phosphatidylcholine to phosphatidic acid and choline. Research has indicated that phospholipase D may play

Interleukin 21 (2,936 words) [view diff] exact match in snippet view article find links to article

Flores I, Casaseca T, Martinez-A C, Kanoh H, Merida I (April 1996). "Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol

Momordica charantia (2,461 words) [view diff] case mismatch in snippet view article find links to article

; Ullah, Abul H. J. (2014-09-09). "Characterization of a Soluble Phosphatidic Acid Phosphatase in Bitter Melon (Momordica charantia)". PLOS ONE. 9 (9):

PACSIN2 (1,129 words) [view diff] exact match in snippet view article find links to article

Molecular function transporter activity cytoskeletal protein binding phosphatidic acid binding protein binding identical protein binding lipid binding cadherin

Glycerol-3-phosphate dehydrogenase 1 (658 words) [view diff] exact match in snippet view article find links to article

dehydrogenase complex mitochondrion extracellular exosome Biological process phosphatidic acid biosynthetic process glycerolipid metabolic process gluconeogenesis

Sec14 (983 words) [view diff] exact match in snippet view article find links to article

of phospholipase D1 and phospholipase B1, which convert PtdCho to phosphatidic acid and choline or PtdCho to glycerophosphocholine, respectively. Sec14p

Substrate presentation (1,870 words) [view diff] exact match in snippet view article find links to article

phosphatidylcholine (PC). When PIP2 increases in the cell PLD translocates to PIP2 where it is exposed to and hydrolyzes PC to phosphatidic acid (red spherical lipid).

Phospholipase A2 group IVD (550 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm cytosol membrane Biological process phosphatidic acid biosynthetic process phosphatidylserine acyl-chain remodeling

C-Raf (8,674 words) [view diff] exact match in snippet view article find links to article

diacylglycerol. Instead, they interact with other lipids, such as ceramide or phosphatidic acid, and even aid in the recognition of activated Ras (GTP-Ras). The close

C13orf38 (842 words) [view diff] exact match in snippet view article find links to article

acyltransferase alpha; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol

UQCC3 (1,008 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function phosphatidic acid binding cardiolipin binding Cellular component mitochondrial respiratory chain complex III mitochondrial

Lipid bilayer fusion (3,384 words) [view diff] case mismatch in snippet view article find links to article

Induced Fusion and Lipid Lateral Segregation in Phosphatidylcholine-Phosphatidic Acid Vesicles". Biochemistry. 25 (22): 6978–87. doi:10.1021/bi00370a600

PTPN11 (4,300 words) [view diff] exact match in snippet view article find links to article

phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C". J. Biol. Chem. 270

Gram domain containing 1b (1,452 words) [view diff] exact match in snippet view article find links to article

function phosphatidylserine binding lipid binding cholesterol binding phosphatidic acid binding cholesterol transfer activity Cellular component membrane

Biosynthesis (6,657 words) [view diff] exact match in snippet view article find links to article

Phosphatidic acid synthesis

C16orf71 (1,795 words) [view diff] exact match in snippet view article find links to article

processes for cellular lipids, ether lipids, glycerophospholipids, phosphatidic acid, and phospholipids AURKA (aurora kinase A) Regulation for G2/M transition

Cholesterol (8,457 words) [view diff] exact match in snippet view article find links to article

decreases or PIP2 increases in the cell, PLD translocates to PIP2 where it is exposed to and hydrolizes PC to phosphatidic acid (red spherical lipid).

Atherosclerosis (11,043 words) [view diff] exact match in snippet view article find links to article

Matsuda, Yoshikazu; Murakami-Murofushi, Kimiko (2015-09-05). "Cyclic phosphatidic acid inhibits the secretion of vascular endothelial growth factor from

N-Acylamides (2,196 words) [view diff] exact match in snippet view article find links to article

by a phospholipase D activity to liberate NAE and, as a byproduct, phosphatidic acid. Mice deficient in the enzyme NAPE-PLD show decreased in a subset

Epidermal growth factor receptor (6,879 words) [view diff] exact match in snippet view article find links to article

phosphatases with the epidermal growth factor receptor in human tumor cells. Phosphatidic acid activates receptor dephosphorylation by PTP1C". The Journal of Biological

RAPGEF3 (3,461 words) [view diff] exact match in snippet view article find links to article

domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane". Proceedings of the National Academy of Sciences

Lipid bilayer (9,777 words) [view diff] exact match in snippet view article find links to article

induced fusion and lipid lateral segregation in phosphatidylcholine-phosphatidic acid vesicles". Biochemistry. 25 (22): 6978–87. doi:10.1021/bi00370a600

Theories of general anaesthetic action (6,745 words) [view diff] exact match in snippet view article find links to article

enzyme bound to and activated TREK-1 channel by the production of phosphatidic acid. These results showed experimentally that the membrane is a physiologically