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searching for DNA binding site 46 found (54 total)

Selection and amplification binding assay (814 words) [view diff] exact match in snippet view article find links to article

(SAAB) is a molecular biology technique typically used to find the DNA binding site for proteins. It was developed by T. Keith Blackwell and Harold M.

E2F (1,853 words) [view diff] exact match in snippet view article find links to article

proteins distantly related to E2F. Binding with DP1,2 provides a second DNA binding site, increasing E2F binding stability. Most E2F have a pocket protein binding

Homeotic protein bicoid (1,170 words) [view diff] no match in snippet view article find links to article

of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site". Journal of Molecular Biology. 356 (5): 1137–1151. doi:10.1016/j.jmb

Wafik El-Deiry (3,601 words) [view diff] exact match in snippet view article find links to article

genomic DNA binding site for the tumor suppressor p53. Nikola Pavletich later crystallized the DNA-binding domain of p53 with the DNA binding site and showed

Leucine rich repeat containing 15 (1,076 words) [view diff] no match in snippet view article find links to article

Gerald, William L.; Haber, Daniel A. (2003-09-01). "Identification of a DNA-binding site and transcriptional target for the EWS–WT1(+KTS) oncoprotein". Genes

Kim Baumann (203 words) [view diff] exact match in snippet view article find links to article

has been the editor in chief since 2016. Baumann, Kim, et al. The DNA binding site of the Dof protein NtBBF1 is essential for tissue-specific and auxin-regulated

Liver X receptor beta (1,201 words) [view diff] exact match in snippet view article find links to article

FF, Alberti S, Gustafsson JA (Apr 1999). "Identification of a novel DNA binding site for nuclear orphan receptor OR1". The Journal of Biological Chemistry

Single-stranded binding protein (1,016 words) [view diff] no match in snippet view article find links to article

encompassing amino acid residues 368-902 contains the single-strand DNA-binding site of ICP8. The HHHV-1 UL5, UL8, and UL52 genes encode an essential heterotrimeric

Cyclin-dependent kinase inhibitor 1C (2,000 words) [view diff] exact match in snippet view article find links to article

"Identification and functional characterization of an intragenic DNA binding site for the spumaretroviral trans-activator in the human p57Kip2 gene"

Intrinsic termination (1,871 words) [view diff] exact match in snippet view article find links to article

inactivates and destabilizes the TEC by weakening interactions in the RNA-DNA binding site and other sites that hold this complex together. The pausing induced

Catabolite Control Protein A (464 words) [view diff] no match in snippet view article find links to article

consists of a homodimer. The N-terminal region of each monomer form a DNA-binding site while the C-terminal portion forms a "regulatory" domain. A short linker

PAX8 (2,329 words) [view diff] exact match in snippet view article find links to article

(December 1997). "PAX 8 regulates human WT1 transcription through a novel DNA binding site". The Journal of Biological Chemistry. 272 (49): 30678–87. doi:10.1074/jbc

EGR1 (1,496 words) [view diff] exact match in snippet view article find links to article

PMID 2028256. S2CID 38000717. Christy B, Nathans D (November 1989). "DNA binding site of the growth factor-inducible protein Zif268". Proceedings of the

RE1-silencing transcription factor (1,940 words) [view diff] no match in snippet view article find links to article

synaptophysin gene transcription through an intronic sequence-specific DNA-binding site". European Journal of Biochemistry. 270 (1): 2–9. doi:10.1046/j.1432-1033

DNA-binding protein (2,637 words) [view diff] no match in snippet view article find links to article

target site. Designing DNA-binding proteins that have a specified DNA-binding site has been an important goal for biotechnology. Zinc finger proteins

IPEX syndrome (2,010 words) [view diff] exact match in snippet view article find links to article

domain. The mutation makes the truncated protein unable to bind to its DNA binding site. This impairs its function concerning Treg development and functioning

Origin recognition complex (2,339 words) [view diff] exact match in snippet view article find links to article

1995). "The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators". Proceedings of the National Academy of Sciences

Position weight matrix (1,880 words) [view diff] no match in snippet view article find links to article

MC (2009). "A reexamination of information theory-based methods for DNA-binding site identification". BMC Bioinformatics. 10: 57. doi:10.1186/1471-2105-10-57

Parthanatos (3,633 words) [view diff] exact match in snippet view article find links to article

(PAAN) that is currently unidentified may be present. Human AIF have a DNA binding site that would indicate that AIF binds directly to the DNA in the nucleus

Germline mutation (3,085 words) [view diff] exact match in snippet view article find links to article

amino acid that is 33-34 amino acids in length. The specificity of the DNA binding site is determined by the specific amino acids at positions 12 and 13 (also

PAX3 (4,308 words) [view diff] exact match in snippet view article find links to article

chromatin structure at target genes, inhibiting PAX3 recognition of its DNA binding site or directly altering PAX3 transcriptional activity. Finally, PAX3 protein

Transcription (biology) (6,898 words) [view diff] exact match in snippet view article

promoters and half in enhancers. The binding of EGR1 to its target DNA binding site is insensitive to cytosine methylation in the DNA. While only small

Meganuclease (2,295 words) [view diff] exact match in snippet view article find links to article

same protein domain) or internally symmetrical monomers (I-SceI). The DNA binding site, which contains the catalytic domain, is composed of two parts on either

Mothers against decapentaplegic homolog 3 (4,115 words) [view diff] exact match in snippet view article find links to article

interface is highly complementary and that one MH1 protein covers a DNA binding site of six base pairs. The MH2 domain mediates the interaction of R-SMADS

Sex-determining region Y protein (4,913 words) [view diff] no match in snippet view article find links to article

accomplishes this by upregulating SOX9, a transcription factor with a DNA-binding site very similar to SRY's. SOX9 leads to the upregulation of fibroblast

Restriction enzyme (5,853 words) [view diff] no match in snippet view article find links to article

activity), and HsdS is important for specificity of the recognition (DNA-binding) site in addition to both restriction digestion (DNA cleavage) and modification

Zinc finger (4,882 words) [view diff] exact match in snippet view article find links to article

for HIV". ClinicalTrials.gov. Christy B, Nathans D (November 1989). "DNA binding site of the growth factor-inducible protein Zif268". Proceedings of the

Aryl hydrocarbon receptor (5,999 words) [view diff] no match in snippet view article find links to article

interactions at a dioxin-responsive enhancer. Mutational analysis of the DNA-binding site for the liganded Ah receptor". The Journal of Biological Chemistry

Human bocavirus (2,977 words) [view diff] no match in snippet view article find links to article

triphosphate binding pocket, the metal ion coordination site, the DNA-binding site and the sensory element. These motifs are in a stretch of approximately

Origin of replication (12,563 words) [view diff] exact match in snippet view article find links to article

1995). "The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators". Proceedings of the National Academy of Sciences

Lac operon (5,253 words) [view diff] exact match in snippet view article find links to article

polymerase (RNAP), a DNA-binding protein, which binds to a specific DNA binding site, the promoter, immediately upstream of the genes. Binding of RNA polymerase

Ivan Erill (1,025 words) [view diff] no match in snippet view article find links to article

(2009). "A reexamination of information theory-based methods for DNA-binding site identification". BMC Bioinformatics. 10: 57. doi:10.1186/1471-2105-10-57

CUT&RUN sequencing (2,049 words) [view diff] no match in snippet view article find links to article

transcription factor-MNase fusion proteins can cleave DNA around the DNA-binding site of the protein of interest. In the adapted process, purified MNase

Bacterial one-hybrid system (1,925 words) [view diff] exact match in snippet view article find links to article

TE, Fahrner TJ, Johnston M, Milbrant J (1991). "Identifying of the DNA binding site for NGFI-B by genetic selection in yeast". Science. 252 (5010): 1296–1300

Gooseberry (gene) (1,670 words) [view diff] no match in snippet view article

in the gsb protein. In Drosophila, this region is classified as a DNA-binding site called a homeodomain. Considering this knowledge, it is believed that

SmeT (1,855 words) [view diff] exact match in snippet view article find links to article

the surface of the protein, in the effector binding site, and in the DNA binding site, there are hydrophobic residues of amino acids. The surface of the

Discovery and development of integrase inhibitors (4,155 words) [view diff] exact match in snippet view article find links to article

may therefore be more specific and bind selectively to the target DNA binding site and hence be less toxic than bifunctional inhibitors that are able

DNA (17,917 words) [view diff] exact match in snippet view article find links to article

not reflect subsequent edits. (Audio help · More spoken articles) DNA binding site prediction on protein DNA the Double Helix Game From the official Nobel

HIF1A (7,419 words) [view diff] no match in snippet view article find links to article

AR (August 2002). "Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53". Proceedings of the National Academy of Sciences of the United

Selective estrogen receptor modulator (6,588 words) [view diff] no match in snippet view article find links to article

In addition, some cofactors bind to ER through the terminals, the DNA-binding site or other binding sites. Thus, one compound can be an ER agonist in

Transcriptional regulation (7,316 words) [view diff] exact match in snippet view article find links to article

promoters and half in enhancers. The binding of EGR1 to its target DNA binding site is insensitive to cytosine methylation in the DNA. While only small

SATB1 (3,024 words) [view diff] exact match in snippet view article find links to article

MP, Nikitina T, Zhurkin VB, et al. (July 2019). "Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense

TAF2 (1,114 words) [view diff] exact match in snippet view article find links to article

5548. PMC 84407. PMID 10409744. Chalkley GE, Verrijzer CP (1999). "DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex

P53 (14,142 words) [view diff] no match in snippet view article find links to article

AR (August 2002). "Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53". Proceedings of the National Academy of Sciences of the United

Zinc finger chimera (4,966 words) [view diff] exact match in snippet view article find links to article

M102604200. PMID 11340073. Christy B, Nathans D (November 1989). "DNA binding site of the growth factor-inducible protein Zif268". Proc. Natl. Acad. Sci

Jennifer Pietenpol (1,517 words) [view diff] no match in snippet view article find links to article

Ott, J.; Mays, D. J.; Pietenpol, J. A. (2007-11-01). "p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm".