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searching for Apolipoprotein E 72 found (164 total)

Granzyme (1,786 words) [view diff] exact match in snippet view article find links to article

separate and distinct roles during atherosclerotic plaque development in apolipoprotein E knockout mice". PLOS ONE. 8 (10): e78939. Bibcode:2013PLoSO...878939H

Common disease-common variant (897 words) [view diff] exact match in snippet view article find links to article

The hypothesis has held in the case of putative causal variants in apolipoprotein E, including APOE ε4, associated with Alzheimer's disease. IL23R has

Liver X receptor alpha (1,641 words) [view diff] exact match in snippet view article find links to article

et al. (Jan 2001). "LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes". Proceedings of the National Academy

Age-related mobility disability (1,574 words) [view diff] exact match in snippet view article find links to article

Medical Sciences 54.4 (1999): M172-M176., Melzer, David et al. "The Apolipoprotein E e4 Polymorphism Is Strongly Associated With Poor Mobility Performance

Imaging genetics (1,052 words) [view diff] exact match in snippet view article find links to article

marked by neuronal cell loss and widespread gray matter atrophy and the apolipoprotein E allele (APOE4) is a widely confirmed genetic risk factor for late-onset

APBB1 (1,459 words) [view diff] exact match in snippet view article find links to article

(Dec 1998). "Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein". J. Biol. Chem. 273 (50):

Gladys Maestre (984 words) [view diff] exact match in snippet view article find links to article

Ming-Xin; Shelanski, Michael; Tycko, Benjamin; Mayeux, Richard (1995). "Apolipoprotein E and alzheimer's disease: Ethnic variation in genotypic risks". Annals

Alzheon (806 words) [view diff] exact match in snippet view article find links to article

S2CID 207844779. Hauser, Paul S.; Ryan, Robert O. (October 2013). "Impact of Apolipoprotein E on Alzheimer's Disease". Current Alzheimer Research. 10 (8): 809–817

Neil McIntosh (paediatrician) (801 words) [view diff] exact match in snippet view article

PMID 15321957. Becher, J-C (9 September 2005). "The distribution of apolipoprotein E alleles in Scottish perinatal deaths". Journal of Medical Genetics

Poliovirus receptor-related 2 (1,179 words) [view diff] exact match in snippet view article find links to article

Herbison CE, et al. (2002). "The poliovirus receptor related 2 (PRR2) and apolipoprotein E genes and coronary heart disease". Journal of Cardiovascular Risk.

NEFM (968 words) [view diff] exact match in snippet view article find links to article

Weisgraber KH, Strittmatter WJ, et al. (1996). "Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins". Exp. Neurol. 138

DAB1 (1,845 words) [view diff] exact match in snippet view article find links to article

receptors, very low density lipoprotein receptor (VLDLR; 192977) and apolipoprotein E receptor-2 (ApoER2; 602600), are also required. Both receptors bound

Mendelian randomization (2,855 words) [view diff] exact match in snippet view article find links to article

Research, Netherlands) in which he advocated a study design using Apolipoprotein E allele as an instrumental variable anchor to study the observed relationship

IDFP (437 words) [view diff] exact match in snippet view article find links to article

Krauss, R. M. (2008). "Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins". Proceedings

FABP2 (901 words) [view diff] exact match in snippet view article find links to article

macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis". Nat. Med. 7 (6): 699–705. doi:10.1038/89076

Prostacyclin synthase (1,212 words) [view diff] exact match in snippet view article find links to article

Fujimaki T, et al. (2009). "Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic

FOXC2 (1,624 words) [view diff] exact match in snippet view article find links to article

Fujimaki T, et al. (2009). "Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic

Cerebral amyloid angiopathy (1,768 words) [view diff] exact match in snippet view article find links to article

cleavage of the APP into Aβ. An immune mechanism has also been proposed. apolipoprotein E (APOE) ε2 and ε4 are associated with increased risk of getting cerebral

GDF11 (3,979 words) [view diff] exact match in snippet view article find links to article

inflammation, consequently decreases atherosclerotic plaques area in apolipoprotein E−/− mice. GDF11 attenuates liver fibrosis via expansion of liver progenitor

Thiosalicylic acid (306 words) [view diff] exact match in snippet view article find links to article

S-trans,trans-Farnesyl Thiosalicylic Acid Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice". Circulation. 105 (20): 2416–2422. doi:10.1161/01.CIR

Insulin-degrading enzyme (2,076 words) [view diff] exact match in snippet view article find links to article

insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele". The American Journal of Pathology. 162 (1): 313–9

Wax ester (1,313 words) [view diff] exact match in snippet view article find links to article

marine copepod Calanus finmarchicus attenuates atherogenesis in female apolipoprotein E-deficient mice". J Nutr. 142 (2012): 508–512. doi:10.3945/jn.111.145698

Interleukin 20 (1,400 words) [view diff] exact match in snippet view article find links to article

expressed in atherosclerosis plaques and promotes atherosclerosis in apolipoprotein E-deficient mice". Arteriosclerosis, Thrombosis, and Vascular Biology

Michael Stuart Brown (3,286 words) [view diff] exact match in snippet view article find links to article

(Feb 1983). "Independent pathways for secretion of cholesterol and apolipoprotein E by macrophages". Science. 219 (4586): 871–3. Bibcode:1983Sci...219

Ciliary neurotrophic factor (1,748 words) [view diff] exact match in snippet view article find links to article

S2CID 35399535. Gutman CR, Strittmatter WJ, Weisgraber KH, Matthew WD (1997). "Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic

Hypothalamic–pituitary–gonadal axis (2,454 words) [view diff] exact match in snippet view article find links to article

associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele". BMC Med. Genet. 9: 37. doi:10.1186/1471-2350-9-37

Amyloid plaques (3,371 words) [view diff] exact match in snippet view article find links to article

distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome)". Proceedings of the National

Young-Ki Paik (1,738 words) [view diff] exact match in snippet view article find links to article

postdoc carrier with John Taylor on molecular cell biology of human apolipoprotein E gene which is involved in transportation of cellular cholesterol from

HDLBP (850 words) [view diff] exact match in snippet view article find links to article

is expressed in human atherosclerotic lesions and colocalizes with apolipoprotein E." Arterioscler. Thromb. Vasc. Biol. 17 (11): 2350–8. doi:10.1161/01

Phosphatidylcholine transfer protein (818 words) [view diff] exact match in snippet view article find links to article

(2006). "Homozygous disruption of Pctp modulates atherosclerosis in apolipoprotein E deficient mice". J. Lipid Res. 47 (11): 2400–7. doi:10.1194/jlr.M600277-JLR200

Syndecan-2 (1,282 words) [view diff] exact match in snippet view article find links to article

pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E." J. Lipid Res. 40 (1): 1–16. doi:10.1016/S0022-2275(20)33334-4. PMID 9869645

UBIAD1 (865 words) [view diff] exact match in snippet view article find links to article

McGarvey TW, Nguyen TB, Malkowicz SB (2005). "An interaction between apolipoprotein E and TERE1 with a possible association with bladder tumor formation"

Methylenetetrahydrofolate reductase (3,737 words) [view diff] exact match in snippet view article find links to article

Nishiyama M, Kato Y, Hashimoto M, Yukawa S, Omori K (May 2000). "Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk

Microtubule-associated protein 2 (1,380 words) [view diff] exact match in snippet view article find links to article

PT (1996). "Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism". Ann. N. Y. Acad. Sci. 777 (1):

Lipoprotein-associated phospholipase A2 (1,378 words) [view diff] exact match in snippet view article find links to article

injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice". Circulation. 103 (20): 2495–500. doi:10.1161/01.cir

Lecanemab (2,556 words) [view diff] exact match in snippet view article find links to article

one or no copy of ApoE4, a certain form of the gene for the protein apolipoprotein E. In August 2024, the Medicines and Healthcare products Regulatory Agency

L. Adrienne Cupples (463 words) [view diff] exact match in snippet view article find links to article

(1997-10-22). "Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis". JAMA. 278 (16): 1349

Alpha-7 nicotinic receptor (2,690 words) [view diff] exact match in snippet view article find links to article

Xianbao (January 2017). "Nicotine Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice by Activating α7 Nicotinic Acetylcholine Receptor on

Bennet Omalu (2,914 words) [view diff] exact match in snippet view article find links to article

Caroline G; Mohammed, Nebil; Lam, Troy; Yue, John K (2018-09-01). "Apolipoprotein E Epsilon 4 Genotype, Mild Traumatic Brain Injury, and the Development

PMEL (gene) (1,534 words) [view diff] exact match in snippet view article

Guillaume van Niel; Ptissam Bergam; Aurelie Di Cicco; et al. (2015). "Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells". Cell

Atheroma (4,377 words) [view diff] exact match in snippet view article find links to article

Induce Atherosclerotic Lesion Regression in Western-Type Diet-Fed Apolipoprotein E Knockout Mice". Biomolecules. 12 (9). MDPI AG: 1205. doi:10.3390/biom12091205

Porphyromonas gingivalis (3,916 words) [view diff] exact match in snippet view article find links to article

immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice". Circulation. 109 (22): 2801–2806. doi:10.1161/01.CIR

Bleomycin hydrolase (1,028 words) [view diff] exact match in snippet view article find links to article

PMID 12477932. Nivet-Antoine V, Coulhon MP, Le Denmat C, et al. (2003). "[Apolipoprotein E and bleomycin hydrolase. Polymorphisms: association with neurodegenerative

Substrate presentation (1,881 words) [view diff] exact match in snippet view article find links to article

rafts in response to astrocyte cholesterol. Cholesterol delivered by apolipoprotein E (ApoE) drives APP to associate with GM1 lipid rafts. When cholesterol

Valerie Wojna (580 words) [view diff] exact match in snippet view article find links to article

and its relationship to HIV-associated neurocognitive disorders and apolipoprotein E in HIV-seropositive women. Journal of neurovirology, 18(6), 488-502

Hilpda (771 words) [view diff] exact match in snippet view article find links to article

accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice". FASEB J. 31 (11): 4971–84. doi:10.1096/fj.201700235R

Substrate presentation (1,881 words) [view diff] exact match in snippet view article find links to article

rafts in response to astrocyte cholesterol. Cholesterol delivered by apolipoprotein E (ApoE) drives APP to associate with GM1 lipid rafts. When cholesterol

Atherosclerosis (11,168 words) [view diff] exact match in snippet view article find links to article

"Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis". Arteriosclerosis, Thrombosis, and

ABCA7 (2,880 words) [view diff] exact match in snippet view article find links to article

2013). "Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4, and the risk of late-onset Alzheimer disease in African Americans"

Inclusion body myositis (3,631 words) [view diff] exact match in snippet view article find links to article

of proteins, including amyloid-β (Aβ), tau, ubiquitinated proteins, apolipoprotein E, and β-synuclein in skeletal muscle. ... active immunization markedly

Nitrotyrosine (917 words) [view diff] exact match in snippet view article find links to article

antioxidant N-acetylcysteine prevents accelerated atherosclerosis in uremic apolipoprotein E knockout mice". Kidney International. 67 (6): 2288–2294. doi:10.1111/j

Olfactory tubercle (3,948 words) [view diff] exact match in snippet view article find links to article

in olfactory functioning due to Alzheimer's disease and the role of apolipoprotein E in olfaction". Annals of the New York Academy of Sciences. 855 (1):

Vitellogenin (1,883 words) [view diff] exact match in snippet view article find links to article

S2CID 19885776. Huebbe P, Rimbach G (August 2017). "Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with

Psychedelic drug (9,054 words) [view diff] exact match in snippet view article find links to article

Inflammation in Vascular Tissue and Cholesterol Levels in High-Fat Diet-Fed Apolipoprotein E Knockout Mice". Sci. Rep. 9 (1): 13444–198. Bibcode:2019NatSR...913444F

Cajal–Retzius cell (3,482 words) [view diff] exact match in snippet view article find links to article

including the very low density lipoprotein receptor (VLDLR), the apolipoprotein E receptor type 2 (ApoER2), and the cytoplasmic adapter protein disabled

Boston criteria (943 words) [view diff] exact match in snippet view article find links to article

in 1995 through the Methods segment of an analysis of CAA and the apolipoprotein E ε4 allele. This was further elaborated in 1996, where the criteria

Derek LeRoith (1,179 words) [view diff] exact match in snippet view article find links to article

Sep;150(9):4395-403. Epub 4 June 2009. doi:10.1210/en.2009-0272 PMID 19497975 Apolipoprotein E deficiency abrogates insulin resistance in a mouse model of type 2

Serum amyloid A1 (4,261 words) [view diff] exact match in snippet view article find links to article

acute phase serum amyloid A does not affect atherosclerotic lesions in apolipoprotein E-deficient mice". Arteriosclerosis, Thrombosis, and Vascular Biology

Homeostatic plasticity (2,006 words) [view diff] exact match in snippet view article find links to article

Yamazaki Y, Zhao N, Caulfield TR, Liu CC, Bu G (September 2019). "Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies". Nature

DNA methylation (13,328 words) [view diff] exact match in snippet view article find links to article

polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E". The Journal of Biological Chemistry. 279 (28): 29147–29154. doi:10

GNMT (3,150 words) [view diff] exact match in snippet view article find links to article

"Deficiency of glycine N-methyltransferase aggravates atherosclerosis in apolipoprotein E-null mice". Molecular Medicine. 18 (5): 744–52. doi:10.2119/molmed

13-Hydroxyoctadecadienoic acid (7,852 words) [view diff] exact match in snippet view article find links to article

macrophage fatty-acid–binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis". Nature Medicine. 7 (6): 699–705. doi:10.1038/89076

Causal model (6,139 words) [view diff] exact match in snippet view article find links to article

1080/00325481.1979.11715231. PMID 450828. Katan MB (March 1986). "Apolipoprotein E isoforms, serum cholesterol, and cancer". Lancet. 1 (8479): 507–8.

Dementia caregiving (6,791 words) [view diff] exact match in snippet view article find links to article

can be complex. One well-understood genetic element is a form of the apolipoprotein E (APOE) gene. One form of this gene, APOE e4, increases the risk of

Jean Vance (1,581 words) [view diff] exact match in snippet view article find links to article

Robert B.; Vance, Dennis E.; Vance, Jean E. (21 February 2007). "Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling

Calponin 2 (2,182 words) [view diff] exact match in snippet view article find links to article

significantly attenuated the development of atherosclerosis lesions in apolipoprotein E knockout (ApoE-/-) mice The expression of calponin 2 is significantly

Prevention of dementia (3,923 words) [view diff] exact match in snippet view article find links to article

M (2004). "Aspirin, NSAIDs, risk of dementia, and influence of the apolipoprotein E epsilon 4 allele in an elderly population". Neuroepidemiology. 23 (3):

Central nervous system effects from radiation exposure during spaceflight (9,537 words) [view diff] exact match in snippet view article find links to article

radiation exposure, and previous head injury, such as concussion. Apolipoprotein E (ApoE) has been shown to be an important and common factor in CNS responses

Nanoparticles for drug delivery to the brain (4,222 words) [view diff] exact match in snippet view article find links to article

in turn transport the liposome nano-delivery system across the BBB. Apolipoprotein E (apoE) is a protein that facilitates transport of lipids and cholesterol

Konstantinos Drosatos (1,250 words) [view diff] exact match in snippet view article find links to article

Temple University University of Cincinnati College of Medicine Thesis Gene regulation and functions of Apolipoprotein E (2007) Website www.drosatos.com

Reinhard Heun (1,548 words) [view diff] exact match in snippet view article find links to article

of Alzheimer's disease, identifying significant associations with apolipoprotein E, clusterin, and phosphatidylinositol-binding clathrin assembly protein

Peter Tontonoz (3,035 words) [view diff] exact match in snippet view article find links to article

(January 16, 2001). "LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes". Proceedings of the National Academy