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searching for Antigen presentation 170 found (259 total)

CD96 (823 words) [view diff] exact match in snippet view article find links to article

during the late phase of the immune response. It may also function in antigen presentation[citation needed]. Alternative splicing occurs at this locus and two

HLA-DM (2,371 words) [view diff] exact match in snippet view article find links to article

antigen DM) is an intracellular protein involved in the mechanism of antigen presentation on antigen presenting cells (APCs) of the immune system. It does

Mannose receptor (3,688 words) [view diff] no match in snippet view article find links to article

Major Histocompatibility Complex (MHC) molecules or other related antigen-presentation molecules. An indirect example of this is the processing of the glycolipid

MHC class II (2,119 words) [view diff] exact match in snippet view article find links to article

multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation". Cell. 145 (2): 268–83. doi:10.1016/j.cell.2011.03.023. PMID 21458045

HLA-DO (1,174 words) [view diff] exact match in snippet view article find links to article

its classical counterparts, which are polymorphic and involved in antigen presentation. Though more remains to be elucidated about the function of HLA-DO

Epstein–Barr virus nuclear antigen 1 (997 words) [view diff] exact match in snippet view article find links to article

well as impairing antigen processing and MHC class I-restricted antigen presentation. This thereby inhibits the CD8-restricted cytotoxic T cell response

ABCB9 (866 words) [view diff] exact match in snippet view article find links to article

MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined;

ABCB6 (830 words) [view diff] exact match in snippet view article find links to article

MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function

CD1A (988 words) [view diff] exact match in snippet view article find links to article

PDBe-KB. Melián A, Beckman EM, Porcelli SA, Brenner MB (1996). "Antigen presentation by CD1 and MHC-encoded class I-like molecules". Curr. Opin. Immunol

ABCB4 (1,213 words) [view diff] exact match in snippet view article find links to article

MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein

DNA vaccine (8,378 words) [view diff] exact match in snippet view article find links to article

platform for monoclonal antibody induction. No risk for infections Antigen presentation by both MHC class I and class II molecules Polarise T-cell response

Bone marrow-derived macrophage (719 words) [view diff] exact match in snippet view article find links to article

cellular debris, releasing cytokines to trigger immune responses, and antigen presentation. BMDMs provide a large homogenous population of macrophages that

B-cell receptor (2,173 words) [view diff] exact match in snippet view article find links to article

receptor transport, which eventually culminates in endocytosis and antigen presentation. B cells' mechanical activity adheres to a pattern of negative and

CD1 (1,695 words) [view diff] exact match in snippet view article find links to article

specialized for antigen presentation. CD1e is also considered a group 1 CD1 molecule, even though it does not function in antigen presentation, contrasting

TAP1 (1,215 words) [view diff] exact match in snippet view article find links to article

Townsend A, Trowsdale J (1993). "The transporters associated with antigen presentation". Semin. Cell Biol. 4 (1): 53–61. doi:10.1006/scel.1993.1007. PMID 8453065

Ketan J. Patel (1,499 words) [view diff] exact match in snippet view article find links to article

2004.08.009. PMID 15327776. Patel, K.J.; Neuberger, M.S. (1993). "Antigen presentation by the B cell antigen receptor is driven by the αβ sheath and occurs

Tripeptidyl peptidase II (986 words) [view diff] exact match in snippet view article find links to article

TPPII in trimming proteasomal degradation products for MHC class I antigen presentation". Immunity. 20 (4): 495–506. doi:10.1016/S1074-7613(04)00074-3. PMID 15084277

Photocarcinogen (661 words) [view diff] exact match in snippet view article find links to article

production of cytokines such as interleukin-10 which indirectly hinder antigen presentation in cells. Moreover, UV radiation frequently leads to mutations in

Signaling lymphocytic activation molecule (1,117 words) [view diff] exact match in snippet view article find links to article

binding between SLAMs is involved in cell-to-cell adhesion during antigen presentation. Signaling lymphocytic activation molecules are a CD2-related surface

PSMB10 (3,483 words) [view diff] exact match in snippet view article find links to article

properties that aid in the release of peptides necessary for MHC class I antigen presentation. The immunoproteasome appears to have a pivotal role in modulating

ABCB8 (580 words) [view diff] exact match in snippet view article find links to article

MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined;

MHC class I (2,917 words) [view diff] exact match in snippet view article find links to article

molecules. It is in this way, the MHC class I-dependent pathway of antigen presentation, that the virus infected cells signal T-cells that abnormal proteins

ERAP2 (2,669 words) [view diff] exact match in snippet view article find links to article

form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation". PLOS Genetics. 6 (10): e1001157. doi:10.1371/journal.pgen.1001157

Antigen transfer in the thymus (1,927 words) [view diff] exact match in snippet view article find links to article

tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation". The Journal of Experimental Medicine. 200 (8): 1039–49. doi:10

Anne La Flamme (336 words) [view diff] exact match in snippet view article find links to article

'Trypanosoma cruzi-infected macrophages are defective in class II antigen presentation,' both from the University of Washington in Seattle, Washington.

Immunodominance (1,394 words) [view diff] exact match in snippet view article find links to article

dendritic cells, can have up to six different types of MHC molecules for antigen presentation. There is a potential for generation of hundreds to thousands of

CD1D (1,840 words) [view diff] exact match in snippet view article find links to article

Melián A, Beckman EM, Porcelli SA, Brenner MB (February 1996). "Antigen presentation by CD1 and MHC-encoded class I-like molecules". Current Opinion in

ERAP1 (3,912 words) [view diff] exact match in snippet view article find links to article

responses by cytotoxic (CD8+) T lymphocytes. In the "endogenous" antigen presentation pathway, proteins synthesized by cells undergo cytosolic degradation

Phagolysosome (2,251 words) [view diff] exact match in snippet view article find links to article

functions: Antigen presentation: In immune cells, the transport of breakdown products out of the phagolysosome is crucial for antigen presentation. Metabolic

CD52 (592 words) [view diff] exact match in snippet view article find links to article

cell subsets: implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation". Blood

Narcolepsy (8,224 words) [view diff] exact match in snippet view article find links to article

disorder. Proposed pathophysiology as an autoimmune disease suggest antigen presentation by DQ0602 to specific CD4+ T cells resulting in CD8+ T-cell activation

TRG (gene) (2,439 words) [view diff] no match in snippet view article

presenting antigens. After activation, these cells may upregulate several antigen-presentation, adhesion, and co-stimulation molecules that mimic dendritic cells

Ap4A (907 words) [view diff] case mismatch in snippet view article find links to article

David Michael (2019-06-28). "Ap4A Regulates Directional Mobility and Antigen Presentation in Dendritic Cells". iScience. 16: 524–534. doi:10.1016/j.isci.2019

Gurdyal Besra (457 words) [view diff] exact match in snippet view article find links to article

tuberculosis T-cell lipid antigens and the elucidation of the CD1 antigen presentation pathway. He is also exploring the immunotherapeutic potential of

Collectin (2,730 words) [view diff] exact match in snippet view article find links to article

T-lymphocytes and IL-2 (interleukin-2) production. SP-D increases bacterial antigen presentation by dendritic cells whereas SP-A blocs differentation of the immature

CD1b (776 words) [view diff] exact match in snippet view article find links to article

PMID 14764708. Shahine A (2018). "The intricacies of self-lipid antigen presentation by CD1b". Molecular Immunology. 104: 27–36. doi:10.1016/j.molimm

CD40 (protein) (2,905 words) [view diff] exact match in snippet view article

activation and proliferation, the B-T cell immune synapses among with antigen presentation The CD40 molecule is a potential target for cancer immunotherapy

CD1E (818 words) [view diff] exact match in snippet view article find links to article

"Entrez Gene: CD1E CD1e molecule". Brigl M, Brenner MB (2004). "CD1: antigen presentation and T cell function". Annu. Rev. Immunol. 22 (1): 817–90. doi:10

Immunopathology (1,245 words) [view diff] exact match in snippet view article find links to article

immune system through various mechanisms, including downregulating antigen presentation, producing immunosuppressive molecules, and inhibiting T cell function

Anne O'Garra (464 words) [view diff] exact match in snippet view article find links to article

immunosuppressive functions of Interleukin-10 (IL-10), which inhibits antigen presentation by dendritic cells and macrophages and reduces their production of

HLA-DR (2,294 words) [view diff] exact match in snippet view article find links to article

1930. PMID 8533083. Parham P, Ohta T (1996). "Population biology of antigen presentation by MHC class I molecules". Science. 272 (5258): 67–74. Bibcode:1996Sci

Transporter associated with antigen processing (838 words) [view diff] case mismatch in snippet view article find links to article

Janeway CA, Travers P, Walport M, Shlomchik M (2001). "Chapter 5, Antigen Presentation to T-lymphocytes". In Janeway, Charles (ed.). Immunobiology: the

TIMD4 (1,093 words) [view diff] exact match in snippet view article find links to article

mediates autophagy at the site of tumor, which leads to reduced antigen presentation leading to increased toleration of tumor by the immune system. Therefore

Toll-like receptor 4 (9,110 words) [view diff] exact match in snippet view article find links to article

antigen presentation and upregulation of costimulatory molecules (such as CD40, CD80 and CD86) on innate immune cells which are required for antigen presentation

ABCB7 (856 words) [view diff] exact match in snippet view article find links to article

MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of

Duck hepatitis B virus (353 words) [view diff] exact match in snippet view article find links to article

Piontek P (2018). "Establishment of a yeast-based VLP platform for antigen presentation". Microbial Cell Factories. 17 (1): 17. doi:10.1186/s12934-018-0868-0

Franca Ronchese (854 words) [view diff] exact match in snippet view article find links to article

Institute for Immunology, Switzerland, where she became interested in antigen presentation by dendritic cells in vivo. In 1994, Ronchese moved to New Zealand

FOXN1 (834 words) [view diff] exact match in snippet view article find links to article

to bind to and regulate genes involved in T-cell maturation and antigen presentation. GRCh38: Ensembl release 89: ENSG00000109101 – Ensembl, May 2017

Autophagosome (1,271 words) [view diff] exact match in snippet view article find links to article

and cell differentiation. For instance, autophagosomes assist in antigen presentation, regulate inflammatory signaling, and contribute to the elimination

Harden M. McConnell (1,555 words) [view diff] exact match in snippet view article find links to article

mimic cell surfaces. For example, this system was used to mimic antigen presentation whereby a specific molecule of the major histocompatibility complex

CD4+ T cells and antitumor immunity (4,000 words) [view diff] exact match in snippet view article find links to article

may actually have mutations in some of the proteins involved in antigen presentation, and as such, evade an immune response. (Dunn et al., 2004) Tumor

Antonio Lanzavecchia (1,709 words) [view diff] exact match in snippet view article find links to article

the advancement of human immunology in three distinct fields: i) antigen presentation and dendritic cell biology; ii) lymphocyte activation and immunological

B cell growth and differentiation factors (3,374 words) [view diff] exact match in snippet view article find links to article

lymphocytes, cells which perform functions including: antibody secretion, antigen presentation, preservation of memory for antigens, and lymphokine secretion).

Birdshot chorioretinopathy (1,294 words) [view diff] exact match in snippet view article find links to article

that specifically bind to HLA-A29 and further supports that the antigen presentation pathway drives the etiology of BSCR. Birdshot chorioretinopathy may

Epoxomicin (333 words) [view diff] exact match in snippet view article find links to article

lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses". J. Immunol. 164 (12): 6147–6157. doi:10.4049/jimmunol

Interleukin 10 (4,619 words) [view diff] exact match in snippet view article find links to article

1991, IL-10 was initially reported to suppress cytokine secretion, antigen presentation and CD4+ T cell activation. Further investigation has shown that

THP-1 cell line (850 words) [view diff] exact match in snippet view article find links to article

models to study the monocyte-macrophage differentiation process, antigen presentation and as a model to examine some macrophage-related physiological processes

ESAT-6 (746 words) [view diff] case mismatch in snippet view article find links to article

tuberculosis Interacts with Beta-2-Microglobulin (β2M) Affecting Antigen Presentation Function of Macrophage". PLOS Pathogens. 10 (10): e1004446. doi:10

CD23 (1,729 words) [view diff] exact match in snippet view article find links to article

"IgE-mediated enhancement of CD4+ T cell responses in mice requires antigen presentation by CD11c+ cells and not by B cells". PLOS ONE. 6 (7): e21760. Bibcode:2011PLoSO

Eftilagimod alpha (2,722 words) [view diff] exact match in snippet view article find links to article

dendritic-cell activator, causing increased antigen presentation to cytotoxic (CD8+) T cells. In the absence of antigen presentation via MHC class II molecules, efti

HLA-DP (905 words) [view diff] exact match in snippet view article find links to article

MHC class II, DP (heterodimer) Protein type cell surface receptor Function Immune recognition and antigen presentation

Pancreatic islet macrophage (805 words) [view diff] case mismatch in snippet view article find links to article

PMC 2575065. PMID 18375440. Calderon, B (2014). "The Central Role of Antigen Presentation in Islets of Langerhans in Autoimmune Diabetes". Curr Opin Immunol

Virus-like particle (2,644 words) [view diff] exact match in snippet view article find links to article

(February 2018). "Establishment of a yeast-based VLP platform for antigen presentation". Microbial Cell Factories. 17 (1): 17. doi:10.1186/s12934-018-0868-0

Brigitte Askonas (858 words) [view diff] exact match in snippet view article find links to article

formation. She went on to investigate macrophages and their role in antigen presentation (1962–1968). From 1963 to 1966 she studied the fate of antigen in

FCGR2B (2,227 words) [view diff] exact match in snippet view article find links to article

increasing the BCR activation threshold and suppressing B cell-mediated antigen presentation to T cells through the ITIM-dependent inhibitory mechanism. Ligation

SCIMP protein (688 words) [view diff] exact match in snippet view article find links to article

II molecule. SCIMP is present in the immunological synapse during antigen presentation between a T cell and an antigen-presenting cell (APC). SCIMP becomes

CD80 (2,435 words) [view diff] exact match in snippet view article find links to article

maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation". The Journal of Experimental Medicine

Apolipoprotein E (6,576 words) [view diff] exact match in snippet view article find links to article

suppressing T cell proliferation, macrophage functioning regulation, lipid antigen presentation facilitation (by CD1) to natural killer T cell as well as modulation

IRF8 (2,321 words) [view diff] exact match in snippet view article find links to article

regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T cells". Blood. 108 (2): 609–617. doi:10.1182/blood-2005-11-4490

ICAM-1 (2,409 words) [view diff] exact match in snippet view article find links to article

Sykulev Y (Jun 2005). "ICAM-1 co-stimulates target cells to facilitate antigen presentation". Current Opinion in Immunology. 17 (3): 251–58. doi:10.1016/j.coi

FCAR (2,216 words) [view diff] exact match in snippet view article find links to article

cell-mediated cytotoxicity, production of reactive oxygen species, and antigen presentation. Despite signaling via ITAMs, which typically initiate activation

APC Activator (525 words) [view diff] case mismatch in snippet view article find links to article

Marija; Maffia, Pasquale (2016). "Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs". Frontiers in Immunology. 7: 481. doi:10

THOP1 (829 words) [view diff] exact match in snippet view article find links to article

destroys antigenic peptides and limits the extent of MHC class I antigen presentation". Immunity. 18 (3): 429–40. doi:10.1016/S1074-7613(03)00058-X. PMID 12648459

Signalosome (765 words) [view diff] exact match in snippet view article find links to article

to induce signal transduction. T-cell receptor (TCR) signalosome: Antigen presentation to T-cells is recognised by the T-cell receptor (TCR), which initiates

Filopodia (2,042 words) [view diff] exact match in snippet view article find links to article

attributed to pathfinding of neurons, early stages of synapse formation, antigen presentation by dendritic cells of the immune system, force generation by macrophages

OSCAR (gene) (583 words) [view diff] exact match in snippet view article

FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells". Blood. 104 (5): 1386–95

Transplant rejection (3,272 words) [view diff] exact match in snippet view article find links to article

tissue, or in donor tissue itself. Since not the result of direct antigen presentation, these may not necessarily be intact MHC molecules but instead other

Immunoproteasome (798 words) [view diff] exact match in snippet view article find links to article

Gregerson DS (2012). "Immunoproteasomes: structure, function, and antigen presentation". Progress in Molecular Biology and Translational Science. 109. Elsevier:

NFAT (2,877 words) [view diff] exact match in snippet view article find links to article

NFATc2 and NFAT2/αA are expressed and fulfil important functions like antigen presentation, proliferation, and apoptosis. Although the impairment of NFAT pathway

Scaffold protein (2,159 words) [view diff] exact match in snippet view article find links to article

activate T cells in vitro or in vivo. How spinophilin facilitates antigen presentation in this case is still unknown though it is possible that spinophilin

Piezophile (1,726 words) [view diff] exact match in snippet view article find links to article

from piezophiles". Seminars in Cell & Developmental Biology. SI: Antigen presentation. 84: 138–146. doi:10.1016/j.semcdb.2018.01.004. ISSN 1084-9521. PMC 6050138

HSPA1L (2,317 words) [view diff] exact match in snippet view article find links to article

enhances antigen-specific tumor immunity by facilitating more efficient antigen presentation to cytotoxic T cells. Though it shares close homology to HSPA1A and

Plasmacytoid dendritic cell (1,833 words) [view diff] no match in snippet view article find links to article

PMID 21219184. Villadangos, José A.; Young, Louise (September 2008). "Antigen-Presentation Properties of Plasmacytoid Dendritic Cells". Immunity. 29 (3): 352–361

PSMC6 (2,202 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

PD-L1 (3,052 words) [view diff] exact match in snippet view article find links to article

PD-1 also contributes to ligand-induced TCR down-modulation during antigen presentation to naive T cells, by inducing the up-regulation of the E3 ubiquitin

Dense granule (2,113 words) [view diff] exact match in snippet view article find links to article

and p38 mitogen-activated protein kinases pathways, and host cell antigen presentation. While not all of the T. gondii GRA proteins have been characterized

Long-lived plasma cell (1,254 words) [view diff] exact match in snippet view article find links to article

exhibit a gene expression signature characterised by down-regulating antigen presentation and B-cell receptor (BCR) function-related genes. Conversely, only

Halobacterium (2,582 words) [view diff] exact match in snippet view article find links to article

Fazeela; Sremac, Marinko; DasSarma, Shiladitya (15 June 2001). "Antigen presentation using novel particulate organelles from halophilic archaea". Journal

Bernard Malissen (637 words) [view diff] exact match in snippet view article find links to article

440-443 Malissen, B. et al., « Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines », Cell, 36, 1984, p

MTDH (1,727 words) [view diff] exact match in snippet view article find links to article

"Pharmacological disruption of the MTDH–SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer"

Centre d'immunologie de Marseille-Luminy (1,600 words) [view diff] exact match in snippet view article find links to article

dendritic cells, thought to play an important role in regulating antigen presentation, as well as the discovery of MafB/M-CSF circuits in hematopoietic

C. Garrison Fathman (960 words) [view diff] exact match in snippet view article find links to article

Transcomplementing hybrid I-A-region gene products function effectively in antigen presentation. J. Exp. Med. 152:759-70. Shizuru, Judith, Gregory, Anita K., Chao

MHC restriction (2,241 words) [view diff] case mismatch in snippet view article find links to article

https://www.ncbi.nlm.nih.gov/books/NBK10757/ Nesmiyanov, P (2020). "Antigen Presentation and Major Histocompatibility Complex". Reference Module in Biomedical

MHC restriction (2,241 words) [view diff] case mismatch in snippet view article find links to article

https://www.ncbi.nlm.nih.gov/books/NBK10757/ Nesmiyanov, P (2020). "Antigen Presentation and Major Histocompatibility Complex". Reference Module in Biomedical

PSMC3 (2,428 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

Maria de Sousa (975 words) [view diff] exact match in snippet view article find links to article

Neefjes J, De Sousa M. (2005) "HFE crosstalks with the MHC class I antigen presentation pathway". Blood 106:971-7. De Sousa, M. 2011. "An outsider's perspective-ecotaxis

Uğur Şahin (6,166 words) [view diff] exact match in snippet view article find links to article

Abderraouf Selmi; Mustafa Diken; et al. (1 January 2008). "Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals"

CBLB (gene) (1,393 words) [view diff] exact match in snippet view article

down-modulation, controlling the activation degree of T cells during antigen presentation. Mutation of the CBLB gene has been associated with autoimmune conditions

APLP2 (1,463 words) [view diff] exact match in snippet view article find links to article

mediate binding of various interactive partners. APLP2 associates with antigen presentation molecules like MHC class I molecules and regulates their surface

Calcium in biology (4,236 words) [view diff] exact match in snippet view article find links to article

(vesicle fusion), neural adaptation T cells Activation in response to antigen presentation to the T cell receptor Myocytes Contraction Activation of protein

PSMC2 (2,572 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

Robert Maki (1,022 words) [view diff] exact match in snippet view article find links to article

(MSKCC). After finishing his MD, he worked with Kenneth Rock on antigen presentation then with Abul Abbas on CD4 T cells in the anticancer immune response

Gluten immunochemistry (5,077 words) [view diff] exact match in snippet view article find links to article

Molberg O, Xia J, Fleckenstein B, Khosla C, Sollid LM (2004). "Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally

HSPA1A (3,267 words) [view diff] exact match in snippet view article find links to article

enhances antigen-specific tumor immunity by facilitating more efficient antigen presentation to cytotoxic T cells. It is also involved in the ubiquitin-proteasome

ADRM1 (1,821 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

PSMC5 (2,856 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

PSMC4 (2,801 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

Cancer immunology (3,766 words) [view diff] exact match in snippet view article find links to article

the surface expression of MHC I). Tumor cells also have defects in antigen presentation pathway, what leads into down-regulation of tumor antigen presentations

Cel-Sci Corporation (1,199 words) [view diff] case mismatch in snippet view article find links to article

least 3 times. Cel-Sci has also worked on LEAPS (Ligand Epitope Antigen Presentation System), a system of therapeutic vaccines for rheumatoid arthritis

Kaposi's sarcoma-associated herpesvirus (5,217 words) [view diff] exact match in snippet view article find links to article

Interleukin 6 homolog, Q2HRC7 K3 and K5 – ubiquitin E3 ligases – regulates antigen presentation K4 – vCCL2 – chemokine K4.1 – vCCL3 – chemokine K8 – transcriptional

Oncolytic herpes virus (1,837 words) [view diff] exact match in snippet view article find links to article

has a deletion of the gene encoding ICP47, a protein that inhibits antigen presentation, and an insertion of a gene encoding GM-CSF, an immune stimulatory

HLA-DQ (2,577 words) [view diff] exact match in snippet view article find links to article

MHC class II, DQ (heterodimer) DQ1 binding pocket with ligand Protein type cell surface receptor Function Immune recognition and antigen presentation

Human leukocyte antigen (5,942 words) [view diff] exact match in snippet view article find links to article

ISBN 978-1-55212-518-2. Parham P, Ohta T (April 1996). "Population biology of antigen presentation by MHC class I molecules". Science. 272 (5258): 67–74. Bibcode:1996Sci

PSMD14 (2,797 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological processes via spatial

Margarita del Val (902 words) [view diff] exact match in snippet view article find links to article

P; Koszinowski, U H (1 September 1992). "Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility

PSMD4 (3,208 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

Skin immunity (1,979 words) [view diff] exact match in snippet view article find links to article

lymphocytes through the skin and are recruited from the peripheral blood. Antigen presentation may occur in peripheral lymphoid tissues. The Langerhans cells, once

Cross-presentation (2,159 words) [view diff] exact match in snippet view article find links to article

and mechanistic separation of cross-presentation and endogenous antigen presentation". Nature Immunology. 9 (5): 558–566. doi:10.1038/ni.1601. PMID 18376402

PSMD1 (3,214 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

Molecular anthropology (4,559 words) [view diff] exact match in snippet view article find links to article

PMID 8533083. Parham P, Ohta T (April 1996). "Population biology of antigen presentation by MHC class I molecules". Science. 272 (5258): 67–74. Bibcode:1996Sci

Nickel allergy (3,692 words) [view diff] exact match in snippet view article find links to article

phase (immunological event) when skin contact to nickel results in antigen presentation to the T cells, and T cell duplication (cloning) occurs. The metal

Bjarne Bogen (1,020 words) [view diff] exact match in snippet view article find links to article

IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells. Nat Biotechnol. Jul;17(7):670-5.PMID 10404160 Corthay

Gas vesicle (2,708 words) [view diff] exact match in snippet view article find links to article

PMID 26900411. Stuart ES, Morshed F, Sremac M, DasSarma S (June 2001). "Antigen presentation using novel particulate organelles from halophilic archaea". Journal

PSMD7 (3,217 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

PSMD2 (3,563 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

HIV (14,236 words) [view diff] exact match in snippet view article find links to article

Schwartz O, Benaroch P (October 2001). "HIV-1 Nef impairs MHC class II antigen presentation and surface expression". Proceedings of the National Academy of Sciences

PfSPZ Vaccine (2,186 words) [view diff] exact match in snippet view article find links to article

R.; Van Rooijen, N; Farber, D. L.; Zavala, F (2010). "Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver

Dictyostelium discoideum (5,243 words) [view diff] exact match in snippet view article find links to article

and axon guidance. Phagocytosis is used in immune surveillance and antigen presentation, while cell-type determination, cell sorting, and pattern formation

Interferon gamma (6,483 words) [view diff] exact match in snippet view article find links to article

responses. Among the effects are: Promotes NK cell activity Increases antigen presentation and lysosome activity of macrophages. Activates inducible nitric

Oligopeptidase (2,808 words) [view diff] exact match in snippet view article find links to article

Oligopeptidase (EC.3.4.24.15) is a novel protein on the route of MHC class I antigen presentation". Biochem Biophys Res Commun. 255 (3): 591–595. doi:10.1006/bbrc

Ramakanth Sarabu (1,180 words) [view diff] case mismatch in snippet view article find links to article

Steven J. Berthel etc. Peptide and Peptide Mimetic Inhibitors of Antigen Presentation by HLA-DR Class II MHC Molecules. Design, Structure−Activity Relationships

Asparagine endopeptidase (1,932 words) [view diff] exact match in snippet view article find links to article

Reinheckel T, Watts C (March 2010). "Distinct protease requirements for antigen presentation in vitro and in vivo". Journal of Immunology. 184 (5): 2423–31. doi:10

Mucosal-associated invariant T cell (3,966 words) [view diff] exact match in snippet view article find links to article

activated in ways that involve, and do not involve, MR1-mediated antigen presentation. However, MR1-independent and MR1-dependent activation elicit separate

Artificial antigen presenting cells (1,426 words) [view diff] exact match in snippet view article find links to article

showed how the lipid membrane functions as a support structure for antigen presentation. Even in the absence of T cells, natural APCs have been found to

Coeliac disease (15,893 words) [view diff] exact match in snippet view article find links to article

Molberg Ø, Xia J, Fleckenstein B, Khosla C, et al. (August 2004). "Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally

PSMC1 (3,859 words) [view diff] exact match in snippet view article find links to article

furthermore, proteins are digested into peptides for MHC class I antigen presentation. To meet such complicated demands in biological process via spatial

Gabrielle Belz (1,291 words) [view diff] exact match in snippet view article find links to article

dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus". Proceedings of the National Academy

Group 1 CD1-restricted T cells (1,272 words) [view diff] exact match in snippet view article find links to article

PMC 3932764. PMID 24362891. Brigl M, Brenner MB (2004-04-01). "CD1: antigen presentation and T cell function". Annual Review of Immunology. 22 (1): 817–890

HLA-A (3,411 words) [view diff] exact match in snippet view article find links to article

process can happen as quickly as 5 minutes after initial foreign antigen presentation, although typically it takes several hours for death to become apparent

Lipid raft (6,662 words) [view diff] exact match in snippet view article find links to article

peptide/MHC-II complexes to the cell surface, and their participation in antigen presentation to T cells. Viruses, as obligate intracellular parasites, have to

Psychoneuroimmunology (5,986 words) [view diff] exact match in snippet view article find links to article

associated with a higher risk of infection. Suppress cell adhesion, antigen presentation, chemotaxis and cytotoxicity. Increase apoptosis. Release of

Mixed connective tissue disease (6,154 words) [view diff] exact match in snippet view article find links to article

variety of other important immunological pathways, including as antigen presentation, pathogenic cytokine secretion, and tissue harm via antibody-directed

Adenovirus early region 1A (2,233 words) [view diff] exact match in snippet view article find links to article

peptide degradation by the immunoproteasome, E1A is able to reduce antigen presentation on adenovirus-infected cells and disrupt the cell’s innate immune

Macrophage polarization (3,077 words) [view diff] exact match in snippet view article find links to article

upregulated expression of arginase-1, mannose receptor MRc1 (CD206), antigen presentation by MHC II system, and production of IL-10 and TGF-𝛽, leading to

PIEZO1 (2,704 words) [view diff] exact match in snippet view article find links to article

have a role in the function of fundamental immune processes, like antigen presentation and phagocytosis. Levels of Piezo1 mRNA have been shown to be increased

Chaperone-mediated autophagy (3,623 words) [view diff] exact match in snippet view article find links to article

inhibitor of NFκB. CMA has also been suggested to contribute to antigen presentation in dendritic cells. CMA is activated during T cell activation due

Oncolytic virus (8,636 words) [view diff] exact match in snippet view article find links to article

been recognized as an ideal backbone for vaccines due to its potent antigen presentation capability, this combines well with its natural oncolytic activities

Primary cutaneous CD30 positive anaplastic large cell lymphoma (843 words) [view diff] exact match in snippet view article find links to article

their expression. Another theory is that Langerhans cell-mediated antigen presentation chronically activates T cells, leading to cutaneous T cell lymphomas

Microchimerism (5,116 words) [view diff] exact match in snippet view article find links to article

D; Price, KA; Zhang, D; Glimcher, LH (May 2007). "Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus". The

NGLY1 (2,886 words) [view diff] exact match in snippet view article find links to article

suggested that NGLY1 is closely involved in MHC class I-mediated antigen presentation. The Ngly1-mediated (glycosylated) Asn-to-Asp deamidation constitutes

Coiled-coil drug delivery (2,897 words) [view diff] exact match in snippet view article find links to article

hemagglutinin system. Some advantages to using SAGE systems for antigen presentation include the ability to remain stable and functional after functionalization

Protective autoimmunity (2,523 words) [view diff] exact match in snippet view article find links to article

glial cells and stem cells. This model infers that the level of antigen presentation (i.e. the amount of MHC-II-self antigen complexes) serves as an indicator

Microvesicle (6,074 words) [view diff] exact match in snippet view article find links to article

pathways. This mechanism of action can be used in processes such as antigen presentation, where MHC molecules on the surface of microvesicle can stimulate

Major facilitator superfamily (5,028 words) [view diff] exact match in snippet view article find links to article

Beutler B (February 2006). "The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9". Nature Immunology

Bruce Beutler (12,123 words) [view diff] exact match in snippet view article find links to article

(January 15, 2006). "The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9". Nature Immunology

Autoinflammatory diseases (2,089 words) [view diff] no match in snippet view article find links to article

have broad immune-modulating functions, including enhancing the antigen-presentation function of dendritic cells, promoting T lymphocyte response and

Helga (Elga) De Vries (1,934 words) [view diff] exact match in snippet view article

promoting T-cell infiltration in MS was critical in establishing the antigen presentation capacity of the blood brain barrier. De Vries later found that monocyte

Melanie Greter (2,494 words) [view diff] exact match in snippet view article find links to article

Becher, Burkhard; Bechmann, Ingo; Greter, Melanie (14 June 2006). "Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize

Cortical thymic epithelial cells (2,881 words) [view diff] exact match in snippet view article find links to article

Hinterberger, Maria; Wirnsberger, Gerald; Kyewski, Bruno (December 2009). "Antigen presentation in the thymus for positive selection and central tolerance induction"

Human genetic resistance to malaria (9,634 words) [view diff] exact match in snippet view article find links to article

Polymorphisms at the HLA loci, which encode proteins that participate in antigen presentation, influence the course of malaria. In West Africa an HLA class I antigen

Computational immunology (4,389 words) [view diff] exact match in snippet view article find links to article

functional relationship between TAP peptide transport and HLA class I antigen presentation. TAP is a transmembrane protein responsible for the transport of

Fam89A (2,102 words) [view diff] exact match in snippet view article find links to article

activators of the canonical NF-κB pathway, involved in promoting antigen presentation in dendritic cells and the production of pro-inflammatory cytokines

Dermal macrophage (2,371 words) [view diff] exact match in snippet view article find links to article

Langerhans cells, rendering dermal macrophages minor contributors to antigen presentation. Pro-inflammatory (M1) macrophages are responsible for the progression

Peptidoglycan recognition protein 1 (7,311 words) [view diff] exact match in snippet view article find links to article

monocytes/macrophages and neutrophils, but not in T cells, is required for optimal antigen presentation and priming of CD4+ T cells in pathogenesis of EAE. PGLYRP1 protein

RNA therapeutics (9,545 words) [view diff] exact match in snippet view article find links to article

Sebastian M, Osterloh P, Schild H, et al. (January 2008). "Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals"

Zihai Li (2,353 words) [view diff] exact match in snippet view article find links to article

antigen gp96/grp94 is an ATPase: implications for protein folding and antigen presentation". The EMBO Journal. 12 (8): 3143–3151. doi:10.1002/j.1460-2075.1993

Stichodactyla toxin (8,640 words) [view diff] exact match in snippet view article find links to article

the peptide's disulfide-bonded structure hinders processing and antigen presentation by antigen-presenting cells. ShK-186 also shares sequence and structural

Lifileucel (2,262 words) [view diff] exact match in snippet view article find links to article

enhance the activity of dendritic cells, which are in charge of antigen presentation, CD8+ and T cell activity. This information can be used to discuss

Jonathan C. Kagan (3,468 words) [view diff] exact match in snippet view article find links to article

expression of cytokines and costimulatory molecules, and MHC-mediated antigen presentation). Additionally, hyperactive dendritic cells uniquely gain the ability

Epigenetics of neurodegenerative diseases (13,392 words) [view diff] exact match in snippet view article find links to article

a gene responsible for inhibiting cytokine secretion/activation, antigen presentation, and macrophage activity, but also for exhibiting anti-tumor effects