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Longer titles found: Microtubule associated scaffold protein 2 (view), B cell scaffold protein with ankyrin repeats 1 (view)

searching for Scaffold protein 190 found (300 total)

alternate case: scaffold protein

Eukaryotic initiation factor 4F (681 words) [view diff] no match in snippet view article find links to article

RNA helicase eIF4A, the cap-binding protein eIF4E, and the large "scaffold" protein eIF4G. The mammalian eIF4F complex was first described in 1983, and
MAPK8IP3 (1,253 words) [view diff] exact match in snippet view article find links to article
protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found
SPTBN4 (747 words) [view diff] exact match in snippet view article find links to article
by the SPTBN4 gene. Spectrin is an actin crosslinking and molecular scaffold protein that links the cell membrane to the actin cytoskeleton, and functions
CNKSR1 (832 words) [view diff] exact match in snippet view article find links to article
Jaffe AB, Aspenström P, Hall A (Feb 2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol
Pericentriolar material (339 words) [view diff] exact match in snippet view article find links to article
Tankyrase-2 TUBE1, Tubulin epsilon chain PCNT, pericentrin, a matrix scaffold protein CDK5RAP2, cyclin dependant kinase receptor associated protein 2, binds
Spectrin, alpha 1 (1,026 words) [view diff] exact match in snippet view article find links to article
by the SPTA1 gene. Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions
Bank1 (59 words) [view diff] exact match in snippet view article find links to article
Bank1 (B-cell scaffold protein with ankyrin repeats 1) is a protein-encoding human gene located on chromosome 4 (4q24. Adaptor protein that binds the proteins
MAP2K1IP1 (1,022 words) [view diff] exact match in snippet view article find links to article
Mitogen-activated protein kinase scaffold protein 1 is a scaffold protein that in humans is encoded by the MAPKSP1 gene. The protein encoded by this gene
DUSP16 (738 words) [view diff] exact match in snippet view article find links to article
interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2". J Biol Chem. 280 (27): 25651–8. doi:10.1074/jbc.M501926200
MAPK8IP2 (1,133 words) [view diff] exact match in snippet view article find links to article
protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway
Assemblin (130 words) [view diff] exact match in snippet view article find links to article
following chemical reaction Cleaves -Ala-Ser- and -Ala-Ala- bonds in the scaffold protein This enzyme is coded by the herpes-virus virion. Chen P, Tsuge H, Almassy
MTUS1 (790 words) [view diff] case mismatch in snippet view article find links to article
Mitochondrial tumor suppressor 1 (MTSG1) or Microtubule-Associated Scaffold Protein 1 (MTUS1) is a candidate tumor suppressor protein encoded by the MTUS1
Sodium-hydrogen exchange regulatory cofactor 2 (1,772 words) [view diff] exact match in snippet view article find links to article
carrier family 9 isoform A3 regulatory factor 2) gene. NHERF-2 is a scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin
Receptor for activated C kinase 1 (2,586 words) [view diff] exact match in snippet view article find links to article
Nissen P, Frank J (October 2004). "Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM". Nature Structural & Molecular
RhoD (837 words) [view diff] case mismatch in snippet view article find links to article
B; Aspenström Pontus; Hall Alan (Feb 2004). "Human CNK1 Acts as a Scaffold Protein, Linking Rho and Ras Signal Transduction Pathways". Mol. Cell. Biol
SHOC2 (425 words) [view diff] exact match in snippet view article find links to article
SHOC2 leucine-rich repeat scaffold protein, leucine rich repeat scaffold protein, SHOC2 leucine rich repeat scaffold protein, NSLH1 External IDs OMIM:
AKAP12 (1,016 words) [view diff] exact match in snippet view article find links to article
associates with protein kinase A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the
CIAO1 (656 words) [view diff] exact match in snippet view article find links to article
forms a complex with FAM96B, MMS19, the co-chaperone HSC20 and the scaffold protein ISCU in order to assist iron-sulfur cluster incorporation into cytoplasmic
CNOT1 (730 words) [view diff] exact match in snippet view article find links to article
of the CCR4-Not complex, which deadenylates mRNAs. CNOT1 acts as a scaffold protein, binding other subunits of the complex. CNOT1 has been shown to interact
BCAR1 (2,846 words) [view diff] exact match in snippet view article find links to article
do not show an overlapping role in development. p130Cas/BCAR1 is a scaffold protein characterized by several structural domains. It possesses an amino
SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article
tyrosine kinase to the RAS pathway. The protein SHC1 also acts as a scaffold protein which is used in cell surface receptors. The three proteins that SHC1
SCRIB (2,156 words) [view diff] exact match in snippet view article find links to article
known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. It was originally isolated
NFAT5 (2,099 words) [view diff] exact match in snippet view article find links to article
also recruits and physically interacts with JIP4, a p38 MAPK-specific scaffold protein. JIP4 binds to downstream kinases, MKK3 and MKK6. This complex then
MAPK8IP1 (1,323 words) [view diff] exact match in snippet view article find links to article
Mary K; Whitmarsh Alan J (March 2003). "The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK". J. Biol. Chem.
Decapping complex (2,321 words) [view diff] exact match in snippet view article find links to article
Decapping Protein 1 (Dcp1) and in higher eukaryotes joined by the scaffold protein VCS. Together with many other accessory proteins, the decapping complex
MAP2K1 (1,513 words) [view diff] exact match in snippet view article find links to article
Ito M; Takamatsu N; Yamamoto K I; Shiba T; Yoshioka K (Dec 2000). "A scaffold protein in the c-Jun NH2-terminal kinase signaling pathways suppresses the
SHANK1 (1,048 words) [view diff] exact match in snippet view article find links to article
Sakagami H, Usuda N, Usada N, Kondo H, Fujii T, Endo S (2005). "A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols)
GRID2 (2,079 words) [view diff] exact match in snippet view article find links to article
Kawamoto S (Nov 2006). "Binding of glutamate receptor delta2 to its scaffold protein, Delphilin, is regulated by PKA". Biochemical and Biophysical Research
PDE4D (1,780 words) [view diff] exact match in snippet view article find links to article
Scotland G, Houslay MD, Bolger GB (May 1999). "The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5
MTORC2 (3,374 words) [view diff] exact match in snippet view article find links to article
(Protor1/2) can only be found mTORC2. Rictor has been shown to be the scaffold protein for substrate binding to mTORC2. Though less understood than mTORC1
IKK2 (2,043 words) [view diff] exact match in snippet view article find links to article
PMID 9891086. Cohen L, Henzel WJ, Baeuerle PA (September 1998). "IKAP is a scaffold protein of the IkappaB kinase complex". Nature. 395 (6699): 292–6. Bibcode:1998Natur
DYNLL2 (892 words) [view diff] exact match in snippet view article find links to article
homodimerization activity • protein heterodimerization activity • scaffold protein binding Cellular component • cytoplasm • cytosol • nucleus • membrane
Citron kinase (2,455 words) [view diff] exact match in snippet view article find links to article
proper contractile ring organization at the end of cytokinesis. The scaffold protein anillin is one of the most crucial partners of RhoA during cytokinesis
Mucin 17 (429 words) [view diff] exact match in snippet view article find links to article
(2008). "The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in
MAP3K13 (451 words) [view diff] exact match in snippet view article find links to article
lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway". J. Biochem. 130 (6): 773–81
Invadopodia (1,519 words) [view diff] exact match in snippet view article find links to article
invadopodia, which involves the interaction of PX domain of Tks5 (a scaffold protein) with phospholipid, PI(3,4)P2 to anchor the invadopodia core to the
RhoH (1,024 words) [view diff] exact match in snippet view article find links to article
(January 2005). "Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells". FEBS Letters. 579 (3): 648–54.
Synthetic antibody (1,160 words) [view diff] exact match in snippet view article find links to article
Ferrigno, P (2010). "Structure-function studies of and engineered scaffold protein derived from Stefin A. I: Development of the SQM variant". PEDS. 23
EIF4A1 (2,571 words) [view diff] exact match in snippet view article find links to article
along with eIF4E, the 5'-terminal cap binding protein, and eIF4G, the scaffold protein that holds eIF4A and eIF4E together. The eIF4F complex is often accompanied
CHUK (2,736 words) [view diff] exact match in snippet view article find links to article
S2CID 4354442. Cohen L, Henzel WJ, Baeuerle PA (September 1998). "IKAP is a scaffold protein of the IkappaB kinase complex". Nature. 395 (6699): 292–6. Bibcode:1998Natur
Sodium bicarbonate cotransporter 3 (516 words) [view diff] exact match in snippet view article find links to article
PMID 15324660. S2CID 2371325. Reiners J, van Wijk E, Märker T, et al. (2006). "Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type
Low-density lipoprotein receptor-related protein 4 (637 words) [view diff] exact match in snippet view article find links to article
binding • apolipoprotein binding • protein homodimerization activity • scaffold protein binding • receptor tyrosine kinase binding • GO:0001948 protein binding
CACNA1G (436 words) [view diff] exact match in snippet view article find links to article
voltage-gated calcium channel activity • calcium channel activity • scaffold protein binding • voltage-gated ion channel activity • ion channel activity
Affimer (2,362 words) [view diff] exact match in snippet view article find links to article
Ferrigno P (May 2010). "Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant". Protein
Keratin 15 (902 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • structural constituent of cytoskeleton • GO:0001948 protein binding • structural molecule
FZD7 (781 words) [view diff] exact match in snippet view article find links to article
"MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap". Oncogene. 23 (36): 6023–30. doi:10.1038/sj
ITPR2 (964 words) [view diff] exact match in snippet view article find links to article
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity • scaffold protein binding • inositol 1,4,5 trisphosphate binding Cellular component •
RHPN1 (361 words) [view diff] exact match in snippet view article find links to article
PMID 15489334. Jaffe AB, Aspenström P, Hall A (2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol
Suberites domuncula (1,309 words) [view diff] exact match in snippet view article find links to article
domuncula also holds the scaffold protein membrane-associated guanylate kinase which encodes a tight junction scaffold protein. A tetraspan receptor can
KIF1B (1,032 words) [view diff] exact match in snippet view article find links to article
protein binding • kinesin binding • ATP binding • kinase binding • scaffold protein binding • plus-end-directed microtubule motor activity Cellular component
ATP2B4 (1,159 words) [view diff] exact match in snippet view article find links to article
sodium channel regulator activity • nitric-oxide synthase binding • scaffold protein binding • metal ion binding • calmodulin binding • nitric-oxide synthase
DYNLL1 (1,527 words) [view diff] exact match in snippet view article find links to article
homodimerization activity • protein heterodimerization activity • scaffold protein binding Cellular component • cytoplasm • cytosol • centrosome • membrane
DLG4 (2,910 words) [view diff] exact match in snippet view article find links to article
SAP90, Dlgh4, PSD-95, SAP90A, discs large homolog 4, discs large MAGUK scaffold protein 4, MRD62 External IDs OMIM: 602887 MGI: 1277959 HomoloGene: 1047 GeneCards:
Pierre Gönczy (1,364 words) [view diff] exact match in snippet view article find links to article
off-resonance atomic force microscopy reveals assembly routes of centriolar scaffold protein SAS-6" (PDF). Nature Nanotechnology. 13 (8): 696–701. Bibcode:2018NatNa
MAP2K2 (1,219 words) [view diff] exact match in snippet view article find links to article
nucleotide binding • protein kinase activity • PDZ domain binding • scaffold protein binding • protein serine/threonine kinase activator activity • metal
Keratin 18 (1,140 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • structural molecule activity • GO:0001948 protein binding • cadherin binding involved in
MAP3K14 (1,285 words) [view diff] exact match in snippet view article find links to article
PMID 9742107. Cohen L, Henzel WJ, Baeuerle PA (1998). "IKAP is a scaffold protein of the IkappaB kinase complex". Nature. 395 (6699): 292–6. Bibcode:1998Natur
CACNA1H (1,255 words) [view diff] exact match in snippet view article find links to article
voltage-gated calcium channel activity • calcium channel activity • scaffold protein binding • metal ion binding • ion channel activity • voltage-gated
Keratin 8 (1,287 words) [view diff] exact match in snippet view article find links to article
Molecular function • GO:0032403 protein-containing complex binding • scaffold protein binding • structural molecule activity • GO:0001948 protein binding
KIAA1530 (248 words) [view diff] exact match in snippet view article find links to article
UVSSA Identifiers Aliases UVSSA, KIAA1530, UVSS3, UV stimulated scaffold protein A External IDs OMIM: 614632 MGI: 1918351 HomoloGene: 13807 GeneCards:
CRIPT (606 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • microtubule binding • scaffold protein binding • PDZ domain binding • GO:0001948 protein binding • GO:0032403 protein-containing
APBA3 (566 words) [view diff] exact match in snippet view article find links to article
"Bcr (breakpoint cluster region) protein binds to PDZ-domains of scaffold protein PDZK1 and vesicle coat protein Mint3". J. Cell Sci. 117 (Pt 23): 5535–41
Membrane-associated guanylate kinase (312 words) [view diff] exact match in snippet view article find links to article
Membrane-associated guanylate kinase (MAGUK) scaffold protein Identifiers Symbol MAGUK InterPro IPR016313
FZD4 (1,139 words) [view diff] exact match in snippet view article find links to article
"MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap". Oncogene. 23 (36): 6023–30. doi:10.1038/sj
HOMER3 (611 words) [view diff] exact match in snippet view article find links to article
Aliases HOMER3, HOMER-3, VESL3, homer scaffolding protein 3, homer scaffold protein 3 External IDs OMIM: 604800 MGI: 1347359 HomoloGene: 37972 GeneCards:
SPTBN1 (1,339 words) [view diff] exact match in snippet view article find links to article
by the SPTBN1 gene. Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions
PHF6 (1,100 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • tubulin binding • enzyme binding • scaffold protein binding • DNA binding • ribonucleoprotein complex binding • histone
CNKSR3 (370 words) [view diff] exact match in snippet view article find links to article
Ziera T, Koo E, Ling K, Wang J, Borden SA, Pearce D (September 2012). "Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates
RASSF1 (848 words) [view diff] exact match in snippet view article find links to article
Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B (Jul 2004). "The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced
MAP3K7 (1,388 words) [view diff] exact match in snippet view article find links to article
transferase activity • protein kinase activity • nucleotide binding • scaffold protein binding • metal ion binding • kinase activity • protein serine/threonine
MAPK3 (1,167 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • GO:0001948 protein binding • nucleotide binding • kinase activity • protein serine/threonine
MAGI3 (619 words) [view diff] exact match in snippet view article find links to article
"MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap". Oncogene. 23 (36): 6023–30. doi:10.1038/sj
SH3RF1 (601 words) [view diff] exact match in snippet view article find links to article
N, Hall A (Apr 1998). "A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways". EMBO J. 17
LST1 (812 words) [view diff] exact match in snippet view article find links to article
J (2005). "Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton". J. Cell Sci. 117
RHPN2 (671 words) [view diff] exact match in snippet view article find links to article
PMID 12473120. Jaffe AB, Aspenström P, Hall A (2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol
P2RY1 (1,080 words) [view diff] exact match in snippet view article find links to article
adenosine receptor binding • G protein-coupled receptor activity • scaffold protein binding • ADP binding • G protein-coupled purinergic nucleotide receptor
MinC (542 words) [view diff] exact match in snippet view article find links to article
ZapA, ZapB and ZipA proteins which preferentially bind to the FtsZ scaffold protein and which are needed to initiate cell division. Concentrations of MinC
Derlin-2 (466 words) [view diff] exact match in snippet view article find links to article
et al. (2006). "Neuronal cotransport of glycine receptor and the scaffold protein gephyrin". J. Cell Biol. 172 (3): 441–51. doi:10.1083/jcb.200506066
KvLQT1 (1,494 words) [view diff] exact match in snippet view article find links to article
involved in atrial cardiac muscle cell action potential repolarization • scaffold protein binding • protein kinase A regulatory subunit binding • calmodulin
Caveolin 2 (1,273 words) [view diff] exact match in snippet view article find links to article
protein-macromolecule adaptor activity • protein homodimerization activity • scaffold protein binding • GO:0001948 protein binding • protein heterodimerization activity
KCNA5 (1,399 words) [view diff] exact match in snippet view article find links to article
rectifier potassium channel activity • potassium channel activity • scaffold protein binding • voltage-gated potassium channel activity involved in atrial
NOS1 (1,022 words) [view diff] exact match in snippet view article find links to article
binding • metal ion binding • heme binding • oxidoreductase activity • scaffold protein binding • calmodulin binding • GO:0001948 protein binding • sodium
TREM2 (878 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • lipopolysaccharide binding • lipoteichoic acid binding • peptidoglycan binding • phospholipid
MAPK10 (1,323 words) [view diff] exact match in snippet view article find links to article
neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this
ADCY5 (964 words) [view diff] exact match in snippet view article find links to article
cyclase activity • phosphorus-oxygen lyase activity • ATP binding • scaffold protein binding • guanylate cyclase activity Cellular component • integral
WDR62 (982 words) [view diff] exact match in snippet view article find links to article
regulatory role on hippocampus development and neurogenesis. WDR62 is a scaffold protein and interacts with different kinases. Prinz et al. showed a significant
IκBα (1,505 words) [view diff] exact match in snippet view article find links to article
2012-05-08. Cohen L, Henzel WJ, Baeuerle PA (September 1998). "IKAP is a scaffold protein of the IkappaB kinase complex". Nature. 395 (6699): 292–6. doi:10.1038/26254
NFS1 (620 words) [view diff] exact match in snippet view article find links to article
"Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly". J. Biol. Chem. 281 (18): 12344–51
Mitogen-activated protein kinase (5,423 words) [view diff] exact match in snippet view article find links to article
yeast cells can still activate them separately, with the help of a scaffold protein Ste5 that is selectively recruited by the G-proteins of the mating
Chromosome 4 (1,731 words) [view diff] exact match in snippet view article find links to article
(Vascular endothelial growth factor receptor 2) KIAA1530: UV stimulated scaffold protein A LCORL: Ligand dependent nuclear receptor corepressor like LDB2: LIM
Bacteriophage scaffolding proteins (157 words) [view diff] exact match in snippet view article find links to article
Scaffold protein B procapsid of bacteriophage phix174 Identifiers Symbol Phage_B Pfam PF02304 InterPro IPR003513 SCOP2 1cd3 / SCOPe / SUPFAM
Iron–sulfur protein (1,552 words) [view diff] exact match in snippet view article find links to article
occurs in two major steps: (1) the Fe/S cluster is assembled on a scaffold protein followed by (2) transfer of the preformed cluster to the recipient
C21orf58 (1,729 words) [view diff] exact match in snippet view article find links to article
paraneoplastic neurological disorders MTUS2 Microtubule associated scaffold protein Role in cell migration and linking of microtubules to plasma membrane
Arrestin beta 1 (1,489 words) [view diff] exact match in snippet view article find links to article
exact functions are not known. Beta-arrestin might also play a role as scaffold protein in the GPCR pathways.[citation needed] Arrestin beta 1 has been shown
WDR68 (733 words) [view diff] exact match in snippet view article find links to article
Schmitz ML (2010). "The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions". EMBO J. 29 (22): 3750–61
Vimentin (2,161 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • structural molecule activity • structural constituent of cytoskeleton • protein C-terminus
Delta-like 1 (1,065 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • calcium ion binding • scaffold protein binding • Tat protein binding • Notch binding • GO:0001948 protein binding Cellular
DLG5 (948 words) [view diff] exact match in snippet view article find links to article
Aliases DLG5, LP-DLG, P-PDLG, discs large homolog 5, discs large MAGUK scaffold protein 5 External IDs OMIM: 604090 MGI: 1918478 HomoloGene: 3486 GeneCards:
HOMER2 (676 words) [view diff] exact match in snippet view article find links to article
CPD, HOMER-2, VESL-2, DFNA68, homer scaffolding protein 2, homer scaffold protein 2 External IDs OMIM: 604799 MGI: 1347354 HomoloGene: 3560 GeneCards:
NISCH (998 words) [view diff] exact match in snippet view article find links to article
membrane as well as early and recycling endosome membranes. It is a scaffold protein related to Sorting nexins and it regulates protein cargo traffic. The
FGF13 (703 words) [view diff] exact match in snippet view article find links to article
"Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase". J. Biol
AKAP5 (1,004 words) [view diff] exact match in snippet view article find links to article
adaptor activity • glutamate receptor binding • GABA receptor binding • scaffold protein binding Cellular component • cytosol • membrane • plasma membrane •
HERG (2,541 words) [view diff] exact match in snippet view article find links to article
• potassium channel activity • protein homodimerization activity • scaffold protein binding • voltage-gated potassium channel activity involved in cardiac
NLGN4X (685 words) [view diff] exact match in snippet view article find links to article
ontology Molecular function • protein homodimerization activity • scaffold protein binding • GO:0004091 carboxylic ester hydrolase activity • neurexin
Interleukin-13 receptor (1,791 words) [view diff] case mismatch in snippet view article find links to article
Balyasnikova IV, Casal JI (June 2015). "IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis"
B-cell receptor (2,143 words) [view diff] exact match in snippet view article find links to article
and is activated by phosphorylated ITAMs and in turn phosphorylates scaffold protein BLNK on multiple sites. After phosphorylation, downstream signalling
Hyaluronan-mediated motility receptor (2,710 words) [view diff] exact match in snippet view article find links to article
ERK1 and forms complexes with ERK1,2 and MEK1, suggesting a role as a scaffold protein that targets these MAP kinases to the nucleus. Extracellularly, RHAMM
Telophase (2,647 words) [view diff] exact match in snippet view article find links to article
nuclear pore components, the most studied of which is the nuclear pore scaffold protein ELYS, which can recognize DNA regions rich in A:T base pairs (in vitro)
YWHAE (1,607 words) [view diff] exact match in snippet view article find links to article
regulator activity • identical protein binding • cadherin binding • scaffold protein binding Cellular component • cytoplasm • cytosol • membrane • kinesin
NLGN3 (855 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • neurexin family protein binding • GO:0004091 carboxylic ester hydrolase activity • cell adhesion
UBTF (1,246 words) [view diff] exact match in snippet view article find links to article
binding • GO:0001948 protein binding • chromatin binding • RNA binding • scaffold protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription
AXIN2 (1,378 words) [view diff] exact match in snippet view article find links to article
Ye Z, Zhang S, Chan SC, Chen YG, Han J, Lin SC (2006). "Axin is a scaffold protein in TGF-β signaling that promotes degradation of Smad7 by Arkadia".
Keratin 5 (2,629 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • structural constituent of cytoskeleton • GO:0001948 protein binding • structural molecule
LSP1 (912 words) [view diff] exact match in snippet view article find links to article
J (2005). "Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton". J. Cell Sci. 117
RNF111 (944 words) [view diff] exact match in snippet view article find links to article
Z, Zhang S, Chan SC, Chen YG, Han J, Lin SC (Apr 2006). "Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia"
MAGI2 (944 words) [view diff] exact match in snippet view article find links to article
tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2". Proc. Natl. Acad. Sci. U.S.A. 97 (8): 4233–8. Bibcode:2000PNAS
Janus kinase 1 (2,341 words) [view diff] exact match in snippet view article find links to article
(September 2003). "The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex". J. Immunol. 171
PANX1 (843 words) [view diff] exact match in snippet view article find links to article
transporter binding • calcium channel activity • channel activity • scaffold protein binding • gap junction channel activity • protease binding • actin
SEPT6 (1,099 words) [view diff] exact match in snippet view article find links to article
JH, Jang SK (April 2007). "An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication". Journal of Virology
CNKSR2 (1,024 words) [view diff] exact match in snippet view article find links to article
the CNKSR2 gene. CNKSR2 is a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream
Caspase 8 (2,274 words) [view diff] exact match in snippet view article find links to article
cysteine-type endopeptidase activity involved in apoptotic signaling pathway • scaffold protein binding • GO:0001948 protein binding • identical protein binding •
SHANK3 (1,457 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • SH3 domain binding • scaffold protein binding • zinc ion binding • protein C-terminus binding • GO:0001948 protein binding
Treacle protein (1,464 words) [view diff] exact match in snippet view article find links to article
polymerase I core binding • protein heterodimerization activity • scaffold protein binding Cellular component • nucleolus • nucleus • fibrillar center
HOMER1 (1,718 words) [view diff] exact match in snippet view article find links to article
HOMER1B, HOMER1C, SYN47, Ves-1, homer scaffolding protein 1, homer scaffold protein 1 External IDs OMIM: 604798 MGI: 1347345 HomoloGene: 3155 GeneCards:
ACO2 (1,874 words) [view diff] exact match in snippet view article find links to article
deficiency. It is caused by a mutation in the gene for iron-sulfur cluster scaffold protein (ISCU), which helps build the Fe-S cluster on which the activity of
Desmoplakin (3,057 words) [view diff] exact match in snippet view article find links to article
ontology Molecular function • protein-macromolecule adaptor activity • scaffold protein binding • structural molecule activity • structural constituent of
FASTKD3 (553 words) [view diff] exact match in snippet view article find links to article
FASTKD3 has been proposed to regulate energy production by serving as a scaffold protein that brings together RNA processing/translation and respiratory components
TRAF5 (1,819 words) [view diff] exact match in snippet view article find links to article
factor 5 is a protein that in humans is encoded by the TRAF5 gene. The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated
DLG2 (1,344 words) [view diff] exact match in snippet view article find links to article
PSD-93, PSD93, chapsyn-110, discs large homolog 2, discs large MAGUK scaffold protein 2 External IDs OMIM: 603583 MGI: 1344351 HomoloGene: 1046 GeneCards:
Uncombable hair syndrome (2,640 words) [view diff] exact match in snippet view article find links to article
found in hair follicles and some parts of hair strands. It serves as a scaffold protein, with involucrin, in cell envelope organization. The trichohyalin gene
Alan Hall (1,935 words) [view diff] exact match in snippet view article find links to article
pathways. Hall used immunoprecipitation assays to show that CNK1, a scaffold protein-like target of Rho, interacts with two Rho-specific GEFs (Net1 and
NLGN1 (887 words) [view diff] exact match in snippet view article find links to article
• protein dimerization activity • cell adhesion molecule binding • scaffold protein binding • GO:0004091 carboxylic ester hydrolase activity • neurexin
DLGAP1 (1,313 words) [view diff] exact match in snippet view article find links to article
PMID 15345747. Suzuki T, Li W, Zhang JP, et al. (2005). "A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols)
CCM2 (1,169 words) [view diff] exact match in snippet view article find links to article
Aliases CCM2, C7orf22, OSM, PP10187, CCM2 scaffolding protein, CCM2 scaffold protein External IDs OMIM: 607929 MGI: 2384924 HomoloGene: 12868 GeneCards:
Wiskott–Aldrich syndrome protein (2,570 words) [view diff] exact match in snippet view article find links to article
actin filaments. Other functions of WASP depend on its activity as a scaffold protein for assembly of effective signalling complexes downstream of antigen
Tyrosine kinase 2 (2,673 words) [view diff] exact match in snippet view article find links to article
(September 2003). "The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex". J. Immunol. United
NCK2 (1,543 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • GO:0001948 protein binding • cytoskeletal anchor activity • signaling receptor complex adaptor
Nav1.5 (2,983 words) [view diff] exact match in snippet view article find links to article
channel activity involved in cardiac muscle cell action potential • scaffold protein binding • protein kinase binding • ubiquitin protein ligase binding
CD19 (3,860 words) [view diff] exact match in snippet view article find links to article
Activated spleen tyrosine kinase (Syk) leads to phosphorylation of the scaffold protein, BLNK, which provides multiple sites for tyrosine phosphorylation and
CDC37 (1,500 words) [view diff] exact match in snippet view article find links to article
protein kinase regulator activity • protein tyrosine kinase activity • scaffold protein binding Cellular component • extracellular exosome • HSP90-CDC37 chaperone
Beta-2 adrenergic receptor (3,297 words) [view diff] exact match in snippet view article find links to article
PMID 31249059. Fan G, Shumay E, Wang H, Malbon CC (Jun 2001). "The scaffold protein gravin (cAMP-dependent protein kinase-anchoring protein 250) binds
FFAT motif (1,606 words) [view diff] exact match in snippet view article find links to article
particular in the A-kinase anchor proteins (AKAPs) AKAP3 and AKAP11 that scaffold protein kinase A and many interactors. This finding has since been confirmed
DLG3 (1,691 words) [view diff] exact match in snippet view article find links to article
NEDLG, PPP1R82, SAP102, XLMR, discs large homolog 3, discs large MAGUK scaffold protein 3 External IDs OMIM: 300189 MGI: 1888986 HomoloGene: 41157 GeneCards:
SDHAF1 (933 words) [view diff] exact match in snippet view article find links to article
that facilitates transfer of the Fe-S prosthetic group from the main scaffold protein ISCU to recipient apo-proteins (i.e. SDHB), Variants of SDHAF1 have
KMT2D (3,566 words) [view diff] exact match in snippet view article find links to article
PA1 are subunits that are unique to KMT2C and KMT2D. KMT2D acts as a scaffold protein within the complex; absence of KMT2D results in destabilization of
TMEM242 (1,508 words) [view diff] exact match in snippet view article find links to article
One of the predicted interacting protein is MAP2K1IP1, which is a scaffold protein. This protein is known to be involved in the MAP Kinase pathway. The
P-bodies (2,032 words) [view diff] exact match in snippet view article find links to article
et al. (2010). These proteins include, but are not limited to, the scaffold protein GW182, Argonaute (Ago), decapping enzymes and RNA helicases. The current
Autophagy-related protein 101 (865 words) [view diff] exact match in snippet view article find links to article
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein - Codes for a general receptor protein that is relatively unknown,
Mdm2 (4,311 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • GO:0001948 protein binding • enzyme binding • metal ion binding • identical protein binding
STK3 (1,828 words) [view diff] exact match in snippet view article find links to article
Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B (July 2004). "The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced
STAT1 (3,607 words) [view diff] exact match in snippet view article find links to article
(September 2003). "The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex". Journal of Immunology
Rifampicin (4,814 words) [view diff] exact match in snippet view article find links to article
acid substitutions at multiple sites within the vaccinia virus D13 scaffold protein confer resistance to rifampicin". Virology. 359 (1): 227–32. doi:10
Mary B. Kennedy (1,219 words) [view diff] exact match in snippet view article find links to article
molecular cloning, and immunocytochemistry to identify the central PSD scaffold protein PSD-95 and its three repeated domains later termed PDZ domains. With
RACGAP1 (1,641 words) [view diff] exact match in snippet view article find links to article
Hall A (March 1998). "A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways". The EMBO Journal
LYRM7 (996 words) [view diff] exact match in snippet view article find links to article
biogenesis machinery, which brings a cluster assembled on the main scaffold protein ISCU. Direct binding of HSC20 to the LYR motif of LYRM7 in a pre-assembled
Endothelial NOS (3,895 words) [view diff] exact match in snippet view article find links to article
binding • actin monomer binding • flavin adenine dinucleotide binding • scaffold protein binding • arginine binding • tetrahydrobiopterin binding • metal ion
Lymphocyte cytosolic protein 2 (2,415 words) [view diff] exact match in snippet view article find links to article
ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76-deficient T cell lines or mice have provided
PARK7 (1,836 words) [view diff] exact match in snippet view article find links to article
enzyme binding • mRNA binding • protein homodimerization activity • scaffold protein binding • small protein activating enzyme binding • single-stranded
TREM1 (1,984 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • scaffold protein binding • signaling receptor activity Cellular component • integral component of membrane • membrane
Botrytis–induced kinase 1 (1,118 words) [view diff] exact match in snippet view article find links to article
transphosphorylation by BAK1 rather than by FLS2 because FLS2 more likely serves as a scaffold protein for the arrangement of the BAK1-FLS2 complex. This hypothesis will
Programmed cell death (6,067 words) [view diff] exact match in snippet view article find links to article
homolog of an autophagy-related (Atg) gene product (mAtg13) and the scaffold protein FIP200. Class III PI3K complex, containing hVps34, Beclin-1, p150 and
Microlissencephaly (2,660 words) [view diff] exact match in snippet view article find links to article
Retrieved 2017-11-07. Houlihan, Shauna L; Feng, Yuanyi (2014-09-23). "The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor
Proto-oncogene tyrosine-protein kinase Src (2,781 words) [view diff] exact match in snippet view article find links to article
enzyme binding • transferase activity • ephrin receptor binding • scaffold protein binding • integrin binding • GO:0001948 protein binding • protein kinase
Suberites (2,517 words) [view diff] case mismatch in snippet view article find links to article
T. Adell et al., Evolution of Metazoan Cell Junction Proteins: The Scaffold Protein MAGI and the Transmembrane Receptor Tetraspanin in the Demosponge Suberites
CUL3 (2,284 words) [view diff] exact match in snippet view article find links to article
protein, a substrate recognition subunit. Cullin 3 protein is a core scaffold protein coordinating other components of the CRL complex. Cullin 3-RING complexes
Bone growth factor (2,024 words) [view diff] exact match in snippet view article find links to article
proteins consist of FRS2-alpha and PLC-gamma. FRS2-alpha acts as a scaffold protein to hold GAB1 and GRB2 which then proteins bind to SHP2 and SOS. These
RELA (6,551 words) [view diff] exact match in snippet view article find links to article
PMID 9738011. Cohen L, Henzel WJ, Baeuerle PA (Sep 1998). "IKAP is a scaffold protein of the IkappaB kinase complex". Nature. 395 (6699): 292–6. Bibcode:1998Natur
PTK2 (4,715 words) [view diff] exact match in snippet view article find links to article
T, Yoshioka K, Miyamori H, Yamada KM, Sato H (September 2002). "A scaffold protein in the c-Jun N-terminal kinase signaling pathway is associated with
GSK-3 (5,227 words) [view diff] exact match in snippet view article find links to article
Beta-catenin by GSK-3 is mediated by the binding of both proteins to Axin, a scaffold protein, allowing Beta-catenin to access the active site of GSK-3. Due to its
WRAP53 (1,837 words) [view diff] exact match in snippet view article find links to article
Coucoravas C, Julner A, Goldstein M, et al. (December 2014). "The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand
FAM43A (1,626 words) [view diff] exact match in snippet view article find links to article
activated kinase 2 (PAK2), melanotransferrin (MFI2), discs large MAGUK scaffold protein 1 (DLG1), and 3-hydroxybutyrate dehydrogenase 1 (BDH1) have been confirmed
Adapter molecule crk (2,930 words) [view diff] exact match in snippet view article find links to article
insulin-like growth factor receptor binding • cytoskeletal protein binding • scaffold protein binding • phosphotyrosine residue binding • SH3 domain binding • SH2
Bernd Pichler (1,524 words) [view diff] case mismatch in snippet view article find links to article
Maria; Moscat, Jorge; Tschöp, Matthias H; Müller, Timo D (2020). "The Scaffold Protein p62 Regulates Adaptive Thermogenesis Through ATF2 Nuclear Target Activation"
FGFR1OP2 (1,134 words) [view diff] exact match in snippet view article find links to article
and division Gene Cards STRN Striatin, calmodulin binding protein Scaffold protein Gene Cards, STRING FAM40A Family with sequence similarity 40, member
Interleukin-1 receptor associated kinase (3,628 words) [view diff] exact match in snippet view article find links to article
therefore critical for both IL-1R and TLR signaling. MyD88 acts as a scaffold protein for the interaction between IRAK-1 and IRAK-4, allowing IRAK-4 to phosphorylate
MDia1 (1,953 words) [view diff] exact match in snippet view article find links to article
autoinhibition RhoB: Helps to localize mDia1 to endosomes Furthermore the scaffold protein (IQGAP1) seems to impact on mDia1. IQGAP1 regulates the localization
C-Raf (8,652 words) [view diff] exact match in snippet view article find links to article
Takamatsu N, Yamamoto KI, Shiba T, Yoshioka K (December 2000). "A scaffold protein in the c-Jun NH2-terminal kinase signaling pathways suppresses the
ANLN (2,956 words) [view diff] exact match in snippet view article find links to article
PMID 7559773. Piekny AJ, Glotzer M (January 2008). "Anillin is a scaffold protein that links RhoA, actin, and myosin during cytokinesis". Current Biology
CEFIP (1,678 words) [view diff] exact match in snippet view article find links to article
DDB1 And CUL4 Associated Factor 7 It's been shown to function as a scaffold protein in kinase signaling. It's also been known to be involved with craniofacial
RAPGEF4 (2,687 words) [view diff] exact match in snippet view article find links to article
exocytosis of insulin granules, Epac2 interacts with Rim2, which is a scaffold protein localized in both plasma membrane and insulin granules, and determines
CASS4 (3,332 words) [view diff] exact match in snippet view article find links to article
C20orf32, CAS4, HEFL, HEPL, Cas scaffolding protein family member 4, Cas scaffold protein family member 4 External IDs MGI: 2444482 HomoloGene: 75128 GeneCards:
Protein phosphorylation (7,845 words) [view diff] exact match in snippet view article find links to article
aggregation of phosphorylated α-Synuclein can be enhanced if a presynaptic scaffold protein Sept4 is present in insufficient quantities. It is important to note
Heat shock protein 90kDa alpha (cytosolic), member A1 (8,135 words) [view diff] exact match in snippet view article
binding • ubiquitin protein ligase binding • tau protein binding • scaffold protein binding Cellular component • cytosol • endocytic vesicle lumen • membrane
LIG3 (3,776 words) [view diff] exact match in snippet view article find links to article
XRCC1 has no enzymatic activity but instead appears to acts as a scaffold protein by interacting with a large number of proteins involved in base excision
DISC1 (4,922 words) [view diff] exact match in snippet view article find links to article
Aliases DISC1, C1orf136, SCZD9, disrupted in schizophrenia 1, DISC1 scaffold protein External IDs OMIM: 605210 MGI: 2447658 HomoloGene: 10257 GeneCards:
Heritability of autism (9,492 words) [view diff] exact match in snippet view article find links to article
Boeckers TM, Gundelfinger ED, Birchmeier W (December 2004). "The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine
Susan Zolla-Pazner (3,328 words) [view diff] exact match in snippet view article find links to article
(2011-10-01). "Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA". Journal of Virology.
NEDD9 (7,975 words) [view diff] exact match in snippet view article find links to article
Golemis (1 August 2015). "Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases". Gene. 567 (1): 1–11. doi:10.1016/J.GENE
CSNK1D (14,714 words) [view diff] exact match in snippet view article find links to article
Hedgehog-driven cancers. In 2018, the interaction between Axin1, a scaffold protein exhibiting important roles in Wnt signaling, and CK1δ/ε were fine-mapped
Embryonal fyn-associated substrate (4,849 words) [view diff] exact match in snippet view article find links to article
PMC 86290. PMID 10982853. Davidson D, Veillette A (Jul 2001). "PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by