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system and might be involved in cell adhesion and motility. It is a candidate gene for (among other things) nonsyndromic deafness. GRCh38: Ensembl release

role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. GRCh38: Ensembl release

subunit gene subfamily of the PMP-22/EMP/MP20 family. This gene is a candidate gene for a familial infantile convulsive disorder with paroxysmal choreoathetosis

to genetic heterogeneity, GWAS analysis must be adjusted for race. Candidate gene association study is commonly used in genetic study before the invention

sought and received re-election to his fifth term, defeating Republican candidate Gene Knorr. Only Burdick filed as a Dem-NPLer, and the endorsed Republican

literature on the role of Arntl2 in regulation of physiology. Arntl2 is a candidate gene for human type 1 diabetes. In overexpression studies, ARNTL2 protein

isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript

the hands, feet, sternum, and lumbosacral spine. A recently proposed candidate gene for preaxial polydactyly is LMBR1, encoding a novel transmembrane receptor

C-terminal region of approximately 200 amino acid residues. TULP1 is a candidate gene for retinitis pigmentosa-14 (RP). Mutation in TULP1 is a rare cause

brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. GRCh38: Ensembl release 89: ENSG00000075290 –

detect the original finding. Therefore, the general approach of candidate gene or candidate gene by environment interaction research in single small studies

"[Distribution and significance of cSNP in KCNA7 gene as a novel NIDDM candidate gene in the population of northeast China]". Yi Chuan. 25 (2): 129–32. PMID 15639836

mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for Dyschromatosis Universalis Hereditaria, a disorder of skin pigment

syndromal X-linked intellectual disability, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has

transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility". Genomics. 72 (1): 113–7. doi:10.1006/geno

generally involving high-throughput methods rather than a more traditional "candidate-gene" approach. In order to understand functional genomics it is important

Flachsbart F, Puca AA, Malovini A, Schreiber S, Nebel A (August 2011). "Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity

mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar

clock fails to function in humans. BMAL1 has also been identified as a candidate gene for susceptibility to hypertension, diabetes, and obesity, and mutations

Dyslexia susceptibility 1 candidate gene 1 protein is a protein that in humans is encoded by the DYX1C1 gene. This protein contains 420-amino acids with

OR6A2 which is located near it on chromosome 11) has been proposed as a candidate gene responsible for the genetic portion of the variation in cilantro preference

neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this

"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis". Eur. J. Hum. Genet. 17 (7): 946–957. doi:10.1038/ejhg.2008

Ishikawa-Brush Y, Tommerup N, Horn N, Monaco AP (1993). "Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein"

the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness. CNTNAP2 has been associated

PLXNA2 gene is associated with schizophrenia. and anxiety. PLXNA2 is a candidate gene for intellectual disability and possibly facial dysmorphism and congenital

one. Based on its cytogenetic location, this gene is considered as a candidate gene for limb-girdle muscular dystrophy. DCTN1 has been shown to interact

Berger W, van de Pol D, Warburg M, et al. (1993). "Mutations in the candidate gene for Norrie disease". Hum. Mol. Genet. 1 (7): 461–5. doi:10.1093/hmg/1

autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders

holoprosencephaly critical region in 21q22.3, exclusion of SIM2 as a candidate gene for holoprosencephaly, and mapping of SIM2 to a region of chromosome

kinesin (KIFC3) that maps to human chromosome 16q13-q21 and thus is a candidate gene for Bardet-Biedl syndrome". Genomics. 52 (2): 219–22. doi:10.1006/geno

protein that in humans is encoded by the ASPSCR1 gene. This gene is a candidate gene for alveolar soft part sarcoma (ASPS). It has been found that ASPSCR1

protein that may function as a transcription factor. This gene was once a candidate gene for the testis-determining factor (TDF) and was erroneously referred

elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the

this as evidence in favor of an effect. The MAO-A gene was the first candidate gene for antisocial behavior and was identified during a "molecular genetic

National Library of Medicine. French Fmf, Consortium (Oct 1997). "A candidate gene for familial Mediterranean fever". Nat Genet. 17 (1): 25–31. doi:10

Some of those candidate genes have been identified but none of the candidate gene studies have been consistently replicated except those relating to the

processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated

encoded by the TUSC2 gene. This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. GRCh38:

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein also known as calcium-response factor (CaRF) is a protein that in humans is

increase the amount of time of visual excitation. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced

Cheyssac C, Dina C, Leprêtre F, et al. (2006). "EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families". Diabetes

histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. GRCm38: Ensembl release 89: ENSMUSG00000039070

transporter), member 5". Fisher E, Nitz I, Lindner I, et al. (2007). "Candidate gene association study of type 2 diabetes in a nested case-control study

ML, Suomela S, Snellman E, Saarialho-Kere U, Kere J (June 2000). "A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated

Jänne PA, Landers JE, Lewis RA, Nussbaum RL (1992). "Isolation of a candidate gene for choroideremia". Proc. Natl. Acad. Sci. U.S.A. 89 (6): 2135–9. Bibcode:1992PNAS

binding domain) is a protein domain found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component

IM, Reis A, Kelsell DP, Field JK (Sep 1999). "Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (TOC): the integration of genetic

MF, Gehron Robey P, Laig-Webster M, Chiong W (August 1997). "PHOG, a candidate gene for involvement in the short stature of Turner syndrome". Human Molecular

interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript

repeats by partial intraexonic splicing. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. GRCh38: Ensembl release 89: ENSG00000125844

novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy". Hum Mol Genet. 8 (7): 1329–36.

itself has also recently been implicated as an autism-related disorder candidate gene. Abrahams BS, Geschwind DH (May 2008). "Advances in autism genetics:

PMID 12477932. Volz A, Melkaoui R, Hildebrandt F, Omran H (2003). "Candidate gene analysis of KIAA0678 encoding a DnaJ-like protein for adolescent nephronophthisis

Furukawa A, Itokawa M, Oishi M (April 2007). "Synaptotagmin XI as a candidate gene for susceptibility to schizophrenia". American Journal of Medical Genetics

Smith MJ, Wilcox SA, Bell KM, Sinclair AH (March 2000). "SOX14 is a candidate gene for limb defects associated with BPES and Möbius syndrome". Human Genetics

Chanock S, Hankinson S, Kraft P, Bergen AW (2009). "Genome-wide and candidate gene association study of cigarette smoking behaviors". PLOS ONE. 4 (2):

2007. PMID 17438352. Aurino S, Piluso G, Saccone V, et al. (2008). "Candidate-gene testing for orphan limb-girdle muscular dystrophies". Acta Myol. 27

non-syndromic forms have been studied genetically using linkage and candidate-gene association studies with only partial success in defining the loci responsible

Purvis I (March 2002). "Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide

John Danforth, Attorney General of Missouri Morris Duncan, perennial candidate Gene Chapman Ralph A. DePugh, Jackson County deputy sheriff Lawrence "Red"

Holgate ST (August 2004). "The discovery and role of ADAM33, a new candidate gene for asthma". Expert Reviews in Molecular Medicine. 6 (17): 1–12. doi:10

malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental

Schnohr P, Tybjaerg-Hansen A (Sep 2006). "Zinc Finger Protein 202: a new candidate gene for ischemic heart disease: The Copenhagen City Heart Study". Atherosclerosis

phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. SHOX2 localises on chromosome 3, so

chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia". Genomics. 45 (2): 425–8. doi:10.1006/geno.1997

chromosome 5p and identification of the heavy dynein chain DNAH5 as a candidate gene". Am. J. Respir. Cell Mol. Biol. 23 (5): 696–702. doi:10.1165/ajrcmb

hand/split foot malformation locus SHFM1 at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development". Hum. Mol. Genet. 5 (5):

of the human zinc transporter protein gene, ZNT4, and exclusion as a candidate gene in different clinical variants of acrodermatitis enteropathica". Arch

associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance". The Journal of Biological Chemistry

rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome

availability during S phase. LETM1 has initially been proposed as a candidate gene for seizures; it functions in ion exchange with potential roles in cell

JC (2009). "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease". Mol. Psychiatry. 14 (11): 1004–16. doi:10

S2CID 34628968. Ferrell RE, Kimak MA, Lawrence EC, Finegold DN (2008). "Candidate gene analysis in primary lymphedema". Lymphatic Research and Biology. 6 (2):

defined as the study of inter-individual variations in whole-genome or candidate gene single-nucleotide polymorphism maps, haplotype markers, and alterations

Leeb: Chromosomal assignment of the canine melanophilin gene (MLPH): a candidate gene for coat color dilution in Pinschers. In: J Hered. 96(7), 2005, page

dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type

breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene". Cancer Genet. Cytogenet. 179 (1): 11–8. doi:10.1016/j.cancergencyto

for the Trump campaign Rocky De La Fuente, businessman and perennial candidate Gene Truono, businessman and former Chief Compliance Officer at PayPal Chuck

associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance". J Biol Chem. 273 (49): 32437–45

structure, cochlear expression, and mutation screening of KCNK6, a candidate gene for DFNA4". J. Neurosci. Res. 75 (1): 25–31. doi:10.1002/jnr.10839.

(1993). "X-linked liver glycogenosis: localization and isolation of a candidate gene". Hum. Mol. Genet. 2 (5): 583–9. doi:10.1093/hmg/2.5.583. PMID 8518797

refinement of the locus on chromosome 12q24.33 to a 2·9-Mb interval and candidate gene analysis". British Journal of Dermatology. 160 (3). Oxford University

PMID 12477932. Vieira AR, McHenry TG, Daack-Hirsch S, et al. (2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

Amouyel P, Dallongeville J (2006). "Lack of association between certain candidate gene polymorphisms and the metabolic syndrome". Molecular Genetics and Metabolism

Kere J (October 2005). "The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia". PLOS Genet. 1 (4): e50. doi:10.1371/journal

cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression". American Journal

hemiplegic migraine locus on 19p13.1-p13.2: exclusion of PRKCSH as a candidate gene. Dutch Migraine Genetic Research Group". Eur. J. Hum. Genet. 4 (6):

monochromacy: linkage analysis and mapping of a cone photoreceptor expressed candidate gene on chromosome 2q11". Genomics. 51 (3): 325–31. doi:10.1006/geno.1998

K, Kato H, Inoue T, Matsuda T, Wake N (August 2004). "Analysis of a candidate gene associated with growth suppression of choriocarcinoma and differentiation

monochromacy: linkage analysis and mapping of a cone photoreceptor expressed candidate gene on chromosome 2q11". Genomics. 51 (3): 325–31. doi:10.1006/geno.1998

K, Kato H, Inoue T, Matsuda T, Wake N (August 2004). "Analysis of a candidate gene associated with growth suppression of choriocarcinoma and differentiation

linkage to the RDP/DYT12 locus on 19q13.2 and evaluation of GRIK5 as a candidate gene". Mov. Disord. 19 (7): 845–7. doi:10.1002/mds.20095. PMID 15254951.

fast-twitch skeletal muscle sarcoplasmic reticulum, and its elimination as a candidate gene for Brody disease". Genomics. 30 (3): 415–24. doi:10.1006/geno.1995

its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. GFRA2 (gene) has been shown to interact

et al. (2004). "Transmission disequilibrium testing of dopamine-related candidate gene polymorphisms in ADHD: confirmation of association of ADHD with DRD4

each steamer duck species. The DYRK1A enzyme has been identified as a candidate gene for flightlessness in steamer ducks. This finding, combined with the

"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis". Eur. J. Hum. Genet. 17 (7): 946–57. doi:10.1038/ejhg.2008

Loon N, Richard CW, James MR, Cox DR, Murnane JP (1992). "Cloning of a candidate gene for ataxia-telangiectasia group D". Am. J. Hum. Genet. 51 (1): 45–54

paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis". BMC Medical Genetics. 8: 74. doi:10.1186/1471-2350-8-74.

anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger". Genomics. 70 (1): 102–12. doi:10.1006/geno

Todd C, Meggit S, Birch-MacHin MA, Rees JL (April 2001). "Expression, candidate gene, and population studies of the melanocortin 5 receptor". The Journal

identification of shared disease haplotypes, and exclusion of TPST1 as a candidate gene". European Journal of Human Genetics. 10 (4): 250–8. doi:10.1038/sj

et al. (2000). "Evaluation and molecular characterization of EHD1, a candidate gene for Bardet-Biedl syndrome 1 (BBS1)". Gene. 240 (1): 227–32. doi:10

Samson RA, Erickson DT, Lyon MF, Brilliant MH (April 2000). "Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death". Proceedings

R.L.; Wu, X.; Li, L. (16 July 2005). "Toward Identification of the Candidate Gene Controlling Anthocyanin Accumulation in Purple Cauliflower (Brassica

Prochazka M (November 2002). "Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians". Diabetes. 51 (11): 3342–6. doi:10

Gane P, Mattei MG, Bailly P, Gibbs B, Colin Y, Cartron JP (Feb 1996). "Candidate gene acting as a suppressor of the RH locus in most cases of Rh-deficiency"

; Potvin, D.; Massaro, M.; Robertson, B. C.; Clegg, S. M. (2023). "Candidate gene polymorphisms are linked to dispersive and migratory behaviour: Searching

Sullivan, and Matthew C. Keller. "No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple

melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-I hyperprolinaemia". Human Genetics. 101 (1): 69–74. doi:10

"Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians". Mol. Cell. Probes. 16 (6): 421–7. doi:10.1006/mcpr

Sander T, Stephani U (September 2010). "Association study of TRPC4 as a candidate gene for generalized epilepsy with photosensitivity". Neuromolecular Med

PMID 8094113. S2CID 54428682. Szepetowski P, Gaudray P (1994). "FCER1B, a candidate gene for atopy, is located in 11q13 between CD20 and TCN1". Genomics. 19

lip and/or palate through genome-wide association studies and in many candidate gene studies. These disorders are caused by mutations in the IRF6 gene and

calcium signaling. In humans, this gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. Mutations in CCDC22

Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K (September 1995). "Candidate gene for the chromosome 1 familial Alzheimer's disease locus". Science. 269

anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger". Genomics. 70 (1): 102–12. doi:10.1006/geno

percent). Another 254 votes (18 percent) went to a second Republican candidate, Gene Decker. However, Hebron was unable to be sworn in because of a constitutional

S2CID 34088649. Larkin EK, Patel SR, Goodloe RJ, et al. (2010). "A candidate gene study of obstructive sleep apnea in European Americans and African Americans"

AH, Li Z, Mark HF, Smith RJ, Jackson CL (2000). "2E4/Kaptin (KPTN)—a candidate gene for the hearing loss locus, DFNA4". Ann Hum Genet. 64 (3): 189–196.

Drazen JM (December 1999). "Neuronal NO synthase (NOS1) is a major candidate gene for asthma". Clin. Exp. Allergy. 29. 29 (Suppl 4): 39–41. PMID 10641565

used for identification of IDDM 11 so that SEL1L gene can serve as a candidate gene for IDDM11. However, the present researchers are object to this thesis

Treiber FA, Chao J, Snieder H, Dong Y (Sep 2008). "Prostasin: a possible candidate gene for human hypertension". American Journal of Hypertension. 21 (9): 1028–33

expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways". Physiological

would shrink as he faced a hotly contested challenge from New Democrat candidate Gene Mitchell and two other candidates. After the election Premier Peter

1995). "Cloning of the beta 3 chain gene (LAMB3) of human laminin 5, a candidate gene in junctional epidermolysis bullosa". Genomics. 25 (1): 192–8. doi:10

"Exclusion of the gastrin-releasing peptide receptor (GRPR) locus as a candidate gene for Rett syndrome". Am. J. Med. Genet. 78 (2): 173–5. doi:10

2013). "The mitochondrial solute carrier SLC25A5 at Xq24 is a novel candidate gene for non-syndromic intellectual disability". Human Genetics. 132 (10):

Niu Z, Yuan W, et al. (2005). "Fine mapping and identification of a candidate gene SSH1 in disseminated superficial actinic porokeratosis". Hum. Mutat

Katayama T; Tohyama M (Jul 2003). "Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth". Mol. Psychiatry

S2CID 10035732. Li, Li; Shu, Yi; Lou, Beiyan; Wu, Hongkun (2012). "Candidate-gene exclusion in a family with inherited non-syndromic dental disorders"

time he came in third, behind the successful New Democratic Party candidate, Gene Long, and the Progressive Conservative candidate, Shannie Duff. Murphy

intergenerational children-of-twins design. Many studies in the past used a candidate gene approach to test whether single genes were associated with anxiety.

deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations". Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8):

Wolford JK, Bogardus C, Prochazka M (Mar 2001). "Analysis of PBX1 as a candidate gene for type 2 diabetes mellitus in Pima Indians". Biochimica et Biophysica

molecular pathway leading to VWS. Prior work also suggested WDR65 as a candidate gene. IRF6 contains two non-coding and seven coding exons and is part of

"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis". Eur. J. Hum. Genet. 17 (7): 946–57. doi:10.1038/ejhg.2008

Cox DR, Epstein EH, Scott MP (Aug 1996). "Human homolog of patched, a candidate gene for the basal cell nevus syndrome". Science. 272 (5268): 1668–71. Bibcode:1996Sci

molecular pathway leading to VWS. Prior work also suggested WDR65 as a candidate gene. IRF6 contains two non-coding and seven coding exons and is part of

glucocorticoids are at increased risk. Matrix metalloproteinase 2 may be a candidate gene for bisphosphonate-associated osteonecrosis of the jaw, since it is

1213. PMID 8530100. Wang X, Bornslaeger EA, Haub O, et al. (1996). "A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related

Kääriäinen H, Kere J (Oct 2005). "The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia". PLOS Genetics. 1 (4): e50. doi:10.1371/journal

Dinah Soar, Big Bertha, Flatman and Doorman. Mr. Immortal refuses one candidate, Gene Lorrene, a leather fetishist calling himself Leather Boy. Turned down

Behrends S, Vehse K, Scholz H, et al. (2000). "Assignment of GUCY1A3, a candidate gene for hypertension, to human chromosome bands 4q31.1→q31.2 by in situ

encoding protein Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein also known as calcium-response factor (CaRF) ARMC9: encoding

GR (Mar 2005). "The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes". Diabetologia. 48 (3): 459–68. doi:10.1007/s00125-005-1675-9

Methods Enable Direct Computation on Phenotypic Descriptions for Novel Candidate Gene Prediction". Frontiers in Plant Science. 10: 1629. doi:10.3389/fpls

PMID 9373149. Vieira AR, McHenry TG, Daack-Hirsch S, et al. (2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

European, East Asian and South Asian ancestry and association with candidate gene polymorphisms". Pigment Cell & Melanoma Research. 29 (2): 156. doi:10

their vicinity. Has similar pathological findings of Type I disease. A candidate gene has been identified on chromosome 1. Complement component 3 is seen

PMID 12747794. Delong R (2007). "GABA(A) receptor alpha5 subunit as a candidate gene for autism and bipolar disorder: a proposed endophenotype with parent-of-origin

Saad A, Guiochon-Mantel A (May 2016). "NOBOX is a strong autosomal candidate gene in Tunisian patients with primary ovarian insufficiency". Clinical Genetics

critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. In addition, a polymorphism

gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. The tetraspanin family includes CD9, CD37, CD53, CD63

gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis". Human Molecular Genetics. 6

mapping for the desired phenotype, the researcher can identify a single candidate gene responsible for the phenotype. The point mutations are at approximately

S2CID 205500587. Hewitt, John K. (2011). "Editorial Policy on Candidate Gene Association and Candidate Gene-by-Environment Interaction Studies of Complex Traits"

Torres-Muñoz I, Gómez-Flores M, Salas-Alanís J, et al. (April 2016). "Candidate gene polymorphisms and risk of psoriasis: A pilot study". Experimental and

GATA4 gene to human chromosome 8 and mouse chromosome 14: Gata4 is a candidate gene for Ds (disorganization)". Genomics. 27 (1): 20–6. doi:10.1006/geno

models of the disease, the lab has recently identified a "very strong candidate gene" for hEDS. This finding, and a greater understanding of cardiac complications

PMID 19060906. Mosbruger TL, Duggal P, Goedert JJ, et al. (2010). "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus". J. Infect.

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma

of the human H-protein gene of the glycine cleavage system (GCSH), a candidate gene for nonketotic hyperglycinemia". Journal of Human Genetics. 46 (7):

the identification and prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the

anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger". Genomics. 70 (1): 102–12. doi:10.1006/geno

(November 1996). "A gene similar to PKD1 maps to chromosome 4q22: a candidate gene for PKD2". Genomics. 38 (1): 1–4. doi:10.1006/geno.1996.0584. PMID 8954772

PMID 20377855. Holt R, Barnby G, Maestrini E, et al. (2010). "Linkage and candidate gene studies of autism spectrum disorders in European populations". European

G, Chanock S, Ridker PM, Hunter DJ (November 2010). "A large-scale candidate gene association study of age at menarche and age at natural menopause".

Thomas D.; Schellenberg, Gerard D.; Tanzi, Rudolph E. (1995-08-18). "Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus". Science. 269

restrictive mechanisms other than physical size. NOS3 has been proposed as a candidate gene for the regulation and timing of reproductive functions, such as menopause

anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger". Genomics. 70 (1): 102–12. doi:10.1006/geno

Mundlos, S; Olsen, B. R.; Selby, P. B.; Owen, M. J. (1997). "Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation

6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene". Clinical Cancer Research. 15 (8): 2666–74. doi:10.1158/1078-0432.ccr-08-2335

waddling and staggering in mice--is carbonic anhydrase (CA) VIII a candidate gene?". Biochem. Soc. Trans. 22 (3): 359S. doi:10.1042/bst022359s. PMID 7821612

PMID 9892356. S2CID 4327273. Amir R, Dahle EJ, Toriolo D, Zoghbi HY (2000). "Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq".

Pflug; Yates; Hoefs-Martin; Shepherd; Cook; Lafayette; Brooks (2019). "A candidate gene approach identifies variants in SLC45A2 that explain dilute phenotypes

Schweyen RJ, Nowikovsky K (Mar 2010). "A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome". Human Molecular Genetics

Duijn, Cornelia M.; Oostra, Ben (1 February 2013). "Identification of a candidate gene for astigmatism". Investigative Ophthalmology & Visual Science. 54 (2):

and isoform-specific tissue expression of human NAPOR (CUGBP2) as a candidate gene for familial arrhythmogenic right ventricular dysplasia". Genomics.

ISBN 978-94-007-2584-3. Srivastava K, Srivastava A, Sharma KL, Mittal B. Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

hematological effect and thus will likely have a good safety profile. A large candidate gene association study published in September 2011 found significant differences

function. Eur Urol, 2004. 45(6): p. 706-13. Hatta, N., et al., Expression, candidate gene, and population studies of the melanocortin 5 receptor. J Invest Dermatol

Butterflies Are Free – Charles T. Knight and Arthur Piantadosi The Candidate – Gene Cantamessa and Richard Portman The Godfather – Bud Grenzbach, Christopher

Gurtenvieh, the Lakenvelder and the Belted Galloway all carry the same candidate gene for the belted phenotype.: 224 : 304  Cattle with this characteristic

Collier GR (2005) The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetes. Diabetologia 48(3):459–468 Itin PH, Fistarol SK

with intravenous bisphosphonate. Matrix metalloproteinase-2 may be a candidate gene for bisphosphonate-associated osteonecrosis of the jaws, since it is

educator and feminist author. KGO Radio host and former presidential candidate Gene Burns. Environmental lawyer, writer and 2024 presidential candidate

Mothers? Schizophrenia Daily News Blog, 2007-11-07 Gross L (2007). "A Candidate Gene for a Biological Marker of Schizophrenia in Mice". PLOS Biology. 5 (11):

Serpico looks for the killer who targets women campaigning for mayoral candidate Gene Rincon. After Serpico discovers that a shady real estate businessman

diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13". BMC Genet. 8: 17. doi:10

(QTL) mapping in 2 different cow strains, SLC39A12 (ZIP12) may be a candidate gene that affects fertility in female Chinese and Nordic Holstein cows. ZIP12

Usami S, Kimberling WJ (December 1999). "Human connexin 30 (GJB6), a candidate gene for nonsyndromic hearing loss: molecular cloning, tissue-specific expression

Francisco. April 5, 2021. [1] Assemblyman Gene Mullin [2] Assembly Member Gene Mullin 19th Assembly District [3] Candidate Gene Mullin, SmartVoter.org

anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger". Genomics. 70 (1): 102–12. doi:10.1006/geno

"Dominant optic atrophy: exclusion and fine genetic mapping of the candidate gene, HRY". Mamm. Genome. 9 (10): 784–7. doi:10.1007/s003359900867. PMID 9745030

Robert "Star" Locke, rancher, building contractor, veteran and perennial candidate Gene Chapman, candidate for President of the United States in 2008 R. Lee

Goedert JJ, Kirk GD, Hoots WK, Tobler LH, et al. (May 2010). "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus". The Journal

by-election was held on 2 August 1972. The seat was won by the Fianna Fáil candidate Gene Fitzgerald. Following the death of Labour Party TD Dan Desmond on 9

"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis". Eur. J. Hum. Genet. 17 (7): 946–57. doi:10.1038/ejhg.2008

differentiation. NM23-1: NM23-1 is the product of a tumor metastasis suppressor candidate gene. Because RORα and REV-ERBα are nuclear receptors that share the same

Bare JW, Bonifas JM, et al. (June 1996). "Human homolog of patched, a candidate gene for the basal cell nevus syndrome". Science. 272 (5268): 1668–1671.

Xuereb J, Cairns NJ, Rubinsztein DC, Blackwell JM (February 2005). "Candidate gene association study of solute carrier family 11a members 1 (SLC11A1) and

novel sarcomeric protein with two Ig-like domains, is encoded by a candidate gene for limb-girdle muscular dystrophy". Human Molecular Genetics. 8 (7):

O'brien ML, et al. (2005). "Molecular analysis of congenital scoliosis: a candidate gene approach". Hum. Genet. 116 (5): 416–9. doi:10.1007/s00439-005-1253-8

"Chromosome 22q12.1 microdeletions: confirmation of the MN1 gene as a candidate gene for cleft palate". European Journal of Human Genetics. 24 (1): 51–8

Riveira-Munoz E, Devuyst O, Belge H, et al. (2008). "Evaluating PVALB as a candidate gene for SLC12A3-negative cases of Gitelman's syndrome". Nephrol. Dial. Transplant

protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. PRPF8 has been shown to

F, Chatterjee N, et al. (2009). Reitsma PH (ed.). "Genome-wide and candidate gene association study of cigarette smoking behaviors". PLOS ONE. 4 (2):

It is because of this that C21orf15 is now being studied as a new candidate gene for the intellectual disability phenotype in Down Syndrome. Down Syndrome

Gamble D, Hardy JA, Rich SS, Singleton A, Meschia JF (November 2009). "Candidate gene polymorphisms for ischemic stroke". Stroke. 40 (11): 3436–42. doi:10

T, Matsushita M, Matsumura T, et al. (2003). "A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density". Mamm. Genome. 13

Metzger, Kelsey J.; Miller, Alexandra; Rhen, Turk (2016). "A novel candidate gene for Temperature-Dependent sex determination in the common snapping turtle"

differentiation-specific genes were found, the most frequently expressed candidate gene was identified as a novel sequence, SUBII-TG. The sequenced region of

AM, Silverberg MS, Brumell JH (2012). "NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced

Poorkaj P, Romano DM, Oshima J, Pettingell WH, et al. (August 1995). "Candidate gene for the chromosome 1 familial Alzheimer's disease locus". Science. 269

Receptor Polymorphisms and the Risk of Complicated Sepsis After Trauma: A Candidate Gene Association Study". Shock. 47 (1): 79–85. doi:10.1097/SHK.0000000000000708

neurotrophic factor (BDNF), located on 11p14.1, has been proposed as a candidate gene for the obesity and excessive eating in a subset of WAGR patients. This

Mycobacterium tuberculosis-infected monocytes reveals IL26 as a new candidate gene for tuberculosis susceptibility". Immunology. 144 (2): 291–301. doi:10

Camara B, Palloix A (1998). "The capsanthin-capsorubin synthase gene: a candidate gene for the y locus controlling the red fruit colour in pepper". Plant Mol

Nimgaonkar V, et al. (May 2011). "Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor β(2) subunit". Molecular Psychiatry

Claudia Dierks, Henning Hamann, Ottmar Distl (2008). Associations between Candidate Gene Markers at a Quantitative Trait Locus on Equine Chromosome 4 Responsible

PMID 17979745. Wang X, Bornslaeger EA, Haub O, et al. (1996). "A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related

"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis". European Journal of Human Genetics. 17 (7): 946–57. doi:10

"Point: population stratification: a problem for case-control studies of candidate-gene associations?". Cancer Epidemiol Biomarkers Prev. 11 (6): 505–512. PMID 12050090

PMID 8444872. Cherif-Zahar B, Raynal V, Gane P, et al. (1996). "Candidate gene acting as a suppressor of the RH locus in most cases of Rh-deficiency"

ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population". Journal of Human Genetics

Kere J (October 2005). "The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia". PLOS Genetics. 1 (4): e50. doi:10.1371/journal

(November 2012). "Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia". Human

Zweers MC, Kucharekova M, Schalkwijk J (March 2005). "Tenascin-X: a candidate gene for benign joint hypermobility syndrome and hypermobility type Ehlers-Danlos

PMID 16079235. Zondervan, Krina T.; Cardon, Lon R. (2007-02-01). "Designing candidate gene and genome-wide case–control association studies". Nature Protocols

Whitney S, Packman S, Gitschier J (January 1993). "Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting

mapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region". Blood Cells, Molecules & Diseases. 24 (3):

believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. APBA3 has been shown to interact with Amyloid

Al-Owain, Mohammed; Kentab, Amal Y. (2015-01-13). "Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened

Al-Owain, Mohammed; Kentab, Amal Y. (2015-01-13). "Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened

Matthew C. (October 2011). "A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry". The American Journal

PMID 19615732. Vieira AR, McHenry TG, Daack-Hirsch S, et al. (2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis". Hum. Mol. Genet. 6 (13): 2317–23

gene SLC6A4 encoding this protein represents an important potential candidate gene for AD risk. Using a meta-analysis approach, Feinn et al. found evidence

Sasaki T, et al. (1997). "Fibulin-2: genetic mapping and exclusion as a candidate gene in Marfan syndrome type 2" (PDF). Eur. J. Hum. Genet. 4 (5): 292–5.

TT, Dong J (2003). "MEPE/OF45, a new dentin/bone matrix protein and candidate gene for dentin diseases mapping to chromosome 4q21". Connect. Tissue Res

individuals with primary focal hyperhidrosis. AQP5 has been identified as a candidate gene in many hyperhidrosis studies. Using a family that had members with

ToppGene is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions

for multigenic traits not clearly defined by a single gene. Once a candidate gene is found, further research is often done on the corresponding (or homologous)

(studies which fail to support a true effect). In genetic epidemiology, candidate-gene studies may produce over 100 false-positive findings for each false-negative

has been associated with the idiopathic form of scoliosis. Several candidate gene studies have found associations between idiopathic scoliosis and genes

Park AK, Lee KM, Park SK, Han S, Han W, et al. (September 2009). "Candidate gene approach evaluates association between innate immunity genes and breast

rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. GRCh38: Ensembl release 89: ENSG00000120008

human lung cancer cell line and Dock8 was also identified as a putative candidate gene associated with progression of gliomas. Autosomal recessive DOCK8 deficiency

candidate Kent Solberg (who had run for the seat in 2008), and independent candidate Gene Chewning (who had run for the seat in 2006). "Macario Saldate IV". Phoenix

453–60. PMID 9154246. Comment: Craddock N, Owen MJ (December 1996). "Candidate gene association studies in psychiatric genetics: a SERTain future?". Molecular

(link) Posnien, N., Koniszewski, N.D.B., Hein, H.J. and Bucher, G. 2011: Candidate gene screen in the red flour beetle tribolium reveals six3 as ancient regulator

Raynal V, Gane P, Mattei MG, Bailly P, Gibbs B, et al. (February 1996). "Candidate gene acting as a suppressor of the RH locus in most cases of Rh-deficiency"

PMID 9655866. Amir R, Dahle EJ, Toriolo D, Zoghbi HY (January 2000). "Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq".

and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions". American Journal of Medical Genetics. Part

3 in a large consanguineous Lebanese family: exclusion of MAG as a candidate gene". Am. J. Hum. Genet. 67 (1): 236–43. doi:10.1086/302980. PMC 1287083

Oettinger, M. A.; Brown, J. M. (1995). "DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect". Science. 267 (5201): 1178–1183. Bibcode:1995Sci

Nakamura Y, Niikawa N, Van de Ven W, Devriendt K (May 2003). "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene

even some similar to roan. Presently, the KIT gene is the primary candidate gene for roan. While a chromosomal inversion of KIT causes tobiano white

unguiculata (L.) Walp]: QTL analysis, physical mapping and identifying a candidate gene using synteny with model legume species". BMC Genomics. 13: 234. doi:10

biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple

arthritis (RA) susceptibility and a recent study identified Tbx3 as a candidate gene for RA in collagen-induced arthritis (CIA) mouse models. The severity

Chiquet BT, Lidral AC, Stal S, et al. (2008). "CRISPLD2: a novel NSCLP candidate gene". Hum. Mol. Genet. 16 (18): 2241–8. doi:10.1093/hmg/ddm176. PMC 3755375

thymus-specific serine protease in the extended HLA complex: a potential candidate gene for autoimmune and HLA-associated diseases". Genes Immun. 3 (5): 306–12

Ropers HH (Jul 1996). "Cloning and characterization of DXS6673E, a candidate gene for X-linked mental retardation in Xq13.1". Human Molecular Genetics

Sweeney WE, Godfrey VL, Cacheiro NL, Wilkinson JE, Woychik RP (1994). "Candidate gene associated with a mutation causing recessive polycystic kidney disease

22q12-q13 breast cancer--associated region: evidence of TMPRSS6 as a candidate gene in an eastern Finnish population". Clin. Cancer Res. 12 (5): 1454–62

conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. MOCOS GRCh38: Ensembl release 89:

"Structure, organization, and expression of the human band 7.2b gene, a candidate gene for hereditary hydrocytosis". J. Biol. Chem. 270 (44): 26358–63. doi:10

McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

PMC 2713119. PMID 19389919. Gizer IR, Ficks C, Waldman ID (July 2009). "Candidate gene studies of ADHD: a meta-analytic review". Human Genetics. 126 (1): 51–90

Noben-Trauth, K.; Naggert, J. K.; North, M. A.; Nishina, P. M. (1996). "A candidate gene for the mouse mutation tubby". Nature. 380 (6574): 534–538. Bibcode:1996Natur

Disteche CM, et al. (May 1994). "Evidence against DNA polymerase beta as a candidate gene for Werner syndrome". Human Genetics. 93 (5): 507–12. doi:10.1007/bf00202813

M, Crow TJ (2006). "Accelerated evolution of Protocadherin11X/Y: A candidate gene-pair for cerebral asymmetry and language". American Journal of Medical

"Mutant small heat shock protein B3 causes motor neuropathy: utility of a candidate gene approach". Neurology. 74 (6): 502–6. doi:10.1212/WNL.0b013e3181cef84a

Schaffner C, Döhner H, Stilgenbauer S, Lichter P (Dec 2000). "BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has

fusca)". ResearchGate. Kim, K. K.; Ji, W. M.; McKnight, T. (April 2018). "Candidate gene network for acylsugar metabolism and plant defense in wild tomato Solanum

DW (2014). "The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease". Human Molecular

Epstein, E. H. Jr.; Scott, M. P. (1996). "Human homolog of patched, a candidate gene for the basal cell nevus syndrome". Science. 272 (5268): 1668–1671.

its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene". Mamm Genome. 10 (12): 1175–8. doi:10.1007/s003359901186. PMID 10594243

Chakrabarti L, Knight SJ, Flannery AV, Davies KE (February 1996). "A candidate gene for mild mental handicap at the FRAXE fragile site". Human Molecular

Nakamura Y, Niikawa N, Van de Ven W, Devriendt K (Apr 2003). "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene

L, Minegishi Y, Lavoie A, et al. (2002). "Analysis of SWAP-70 as a candidate gene for non-X-linked hyper IgM syndrome and common variable immunodeficiency"

its exclusion as a polycystic kidney and hepatic disease 1 (PKHD1) candidate gene". Mamm Genome. 10 (12): 1175–8. doi:10.1007/s003359901186. PMID 10594243

beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. There are two alternatively

(2000). "The cell cycle control gene ZAC/PLAGL1 is imprinted--a strong candidate gene for transient neonatal diabetes". Hum. Mol. Genet. 9 (3): 453–60. doi:10

Keller MC (October 2011). "A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry". The American Journal

syndrome critical interval: transcription map, genomic contig, and candidate gene analysis". Eur. J. Hum. Genet. 9 (12): 892–902. doi:10.1038/sj.ejhg

Nakamura Y, Niikawa N, Van de Ven W, Devriendt K (Apr 2003). "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene

retinitis pigmentosa, construction of a YAC contig and investigation of the candidate gene retinal fascin". Eur J Hum Genet. 7 (3): 332–8. doi:10.1038/sj.ejhg

Koprivnikar K, et al. (1996). "Transcriptional map of the Treacher Collins candidate gene region". Genome Res. 6 (1): 26–34. doi:10.1101/gr.6.1.26. PMID 8681136

Z, Mark HF, Smith RJ, Jackson CL (May 2000). "2E4/Kaptin (KPTN)--a candidate gene for the hearing loss locus, DFNA4". Annals of Human Genetics. 64 (Pt

knockdown based on an independent validation. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and

in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product". J. Cell Sci. 118 (Pt 18): 4253–60. doi:10.1242/jcs.02545.

2000). "The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome". Genomics. 64 (3): 277–85. doi:10

thriving in the presence of the herbicide. The next step is to isolate the candidate gene. The cell containing the gene is opened and the DNA is purified. The

sensorineural hearing loss (DFNA5) to a 2-cM region, and exclusion of a candidate gene that is expressed in the cochlea". Eur J Hum Genet. 5 (6): 397–405.

breakpoints and identification of XPNPEP2 as a premature ovarian failure candidate gene". Cytogenet. Cell Genet. 89 (1–2): 44–50. doi:10.1159/000015560. PMID 10894934

allele and unmethylated on the active paternal allele. MeCP2, which is a candidate gene for Rett syndrome, has been shown to affect regulation of expression

submissions would remove many real SNPs. Errors in the dbSNP can hamper candidate gene association studies and haplotype-based investigations. Errors may also

Uitterlinden AG, Nijsten T, Kayser M, Liu F (Feb 2013). "Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous

018. PMID 26266996. Lee YH, Choi SJ, Ji JD, Song GG (February 2012). "Candidate gene studies of fibromyalgia: a systematic review and meta-analysis". Rheumatology

reliable genetic markers are known. Currently, the most interesting candidate gene is BTNL2; several HLA-DR risk alleles are also being investigated. In

vulnerable to the adverse influence of these friends. Results from specific candidate gene studies have been mixed. For instance, in a study of nicotine use Johnson

pbio.0040082. PMC 1382011. PMID 16494532. Luikart, G.; et al. (2008). "Candidate gene microsatellite variation is associated with parasitism in wild bighorn

Morant P, Fournier G, Mangin P, Berthon P, Cussenot O (2002). "CHC1-L, a candidate gene for prostate carcinogenesis at 13q14.2, is frequently affected by loss

(Inpp5b) to distal mouse chromosome 4 and its exclusion as a candidate gene for dysgenetic lens". Genomics. 28 (2): 280–5. doi:10.1006/geno.1995

McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

1097. PMID 9847074. Clark RM, Marker PC, Kingsley DM (2001). "A novel candidate gene for mouse and human preaxial polydactyly with altered expression in

Steen VM, Dale AM, Matthews RT, Agartz I, Andreassen OA (Jan 2011). "Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal

and singer-songwriter Gene Amondson, Prohibition Party presidential candidate Gene "Bean" Baxter, co-host of KROQ's Kevin and Bean radio morning show Steve

(2009). Bertsch, B. et al. Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders. Methods 37, 274-9 (2005)

Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y (May 2009). "Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with

Kambouris M, El-Shantil H (June 2014). "Utilization of gene mapping and candidate gene mutation screening for diagnosing clinically equivocal conditions: a

angiotensinase C gene (HUMPCP) maps to 11q14 within 700 kb of D11S901: a candidate gene for essential hypertension". Genomics. 44 (3): 365–7. doi:10.1006/geno

Bogardus C, Shuldiner AR, Baier LJ (May 2007). "Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated

factors which bind to histone promoter regions. In budding yeast, the candidate gene for activation of histone gene expression is SBF. SBF is a transcription

et al. (Jul 1996). "Identification of a novel gene, ETX1 from Xp21.1, a candidate gene for X-linked retintis pigmentosa (RP3)". Hum Mol Genet. 4 (12): 2347–53

(Oct 2013). "The genetics of dilated cardiomyopathy: a prioritized candidate gene study of LMNA, TNNT2, TCAP, and PLN". Clinical Cardiology. 36 (10):

mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome

Hildesheim J, Fornace AJ (2003). "Gadd45a: an elusive yet attractive candidate gene in pancreatic cancer". Clin. Cancer Res. 8 (8): 2475–9. PMID 12171872

As the pharmacological target of warfarin, VKORC1 is considered a candidate gene for the variability in warfarin response. Previous researches have shown

party primaries took place. Candidates included Democratic perennial candidate Gene Kelly, along with Independent candidates Tommy Calvert, James Lyle Peterson

determined; however, it is speculated that it may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified

processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for processes involved in cell transformations involved in neuroblastoma

Holguin B, Small K, Nesburn AB, Kenney MC (August 2006). "SOD1: a candidate gene for keratoconus". Investigative Ophthalmology & Visual Science. 47 (8):

"Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study". Frontiers in Pharmacology. 8: 347. doi:10.3389/fphar

JC (2009). "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease". Mol. Psychiatry. 14 (11): 1004–16. doi:10

Braat DD, Schoute F, Hoefsloot LH (Jul 2001). "DAZLA: an important candidate gene in male subfertility?". Journal of Assisted Reproduction and Genetics

in cDNA screening as a possible cancer development and progression candidate gene. Unpublished data from Zhang et al. indicates that FAM43A could possess

Wasmuth JJ (January 1996). "Transcriptional map of the Treacher Collins candidate gene region". Genome Research. 6 (1): 26–34. doi:10.1101/gr.6.1.26. PMID 8681136

S2CID 21757455. Lau Y, Chou P, Iezzoni J, et al. (2001). "Expression of a candidate gene for the gonadoblastoma locus in gonadoblastoma and testicular seminoma"

sensorineural hearing loss (DFNA5) to a 2-cM region, and exclusion of a candidate gene that is expressed in the cochlea". Eur J Hum Genet. 5 (6): 397–405.

Lee AT, Karlson EW, et al. (December 2005). "Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North

and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis. SAFB has been shown to interact with: Estrogen

Oono K, Fujita T, et al. (Jul 2003). "Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth". Molecular Psychiatry

covariate in some studies of characterization of personality traits. Candidate gene approach focus on genes whose function suggests an association with

Kumar S (1999). "Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q13". Hum. Hered

Scarpini E, De Riz M, Comi C, Venturelli E, et al. (October 2007). "Candidate gene analysis of SPARCL1 gene in patients with multiple sclerosis". Neuroscience

1999). "SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast"

within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis". Genomics. 79 (4): 475–8. doi:10

(PPP2R5B) to a 0.5-Mb region of chromosome 11q13 and its exclusion as a candidate gene for multiple endocrine neoplasia type 1 (MEN1)". Human Genetics. 100

Peil, Andreas; Richter, Klaus; Zini, Elena; Gessler, Cesare (2013). "A candidate gene for fire blight resistance in Malus × robusta 5 is coding for a CC–NBS–LRR"

PMID 29527097. Kyei Barffour I, Kyei Baah Kwarkoh R (March 2021). "GREB1L as a candidate gene of Mayer–Rokitansky–Küster–Hauser Syndrome". Eur J Med Genet. 64 (3):

Bochum S, Cancel-Tassin G, Cussenot O, et al. (September 2002). "A candidate gene approach within the susceptibility region PCaP on 1q42.2-43 excludes

for whole exome sequencing may replace DNA microarray technology for candidate gene evaluation. Biological parents should be tested with fluorescence in

Vliet-Ostaptchouk JV, et al. (2006). "Identification of TUB as a novel candidate gene influencing body weight in humans". Diabetes. 55 (2): 385–9. doi:10

seen in other mitochondrial disorders, this was considered the best candidate gene. After interrogating the Baylor Genetic Laboratory clinical database

OCLC 1011064243. Sava GP, Speedy HE, Houlston RS (January 2014). "Candidate gene association studies and risk of chronic lymphocytic leukemia: a systematic

disease-causing variants of large effect have been found to lie within exomes in candidate gene studies, and because of negative selection, are found in much lower

Rivolta C (2009). "Ultra high throughput sequencing excludes MDH1 as candidate gene for RP28-linked retinitis pigmentosa". Molecular Vision. 15: 2627–33

Within the theoretical framework of the multi-component model, one candidate gene has been proposed, namely ROBO1 for the hypothetical phonological loop

ligation-dependent probe amplification (MLPA), meaning there is no obvious candidate gene. However, most certain UBR1 mutations predict premature translational

Tam PO, Fan DS, Fan BJ, Pang CP (2003). "TGFbeta-induced factor: a candidate gene for high myopia". Invest. Ophthalmol. Vis. Sci. 44 (3): 1012–5. doi:10

Buring JE, Chen C, Hankinson SE, et al. (November 2010). "A large-scale candidate gene association study of age at menarche and age at natural menopause".

Wuebbles, Ryan D.; Jones, Peter L. (June 2009). "Muscular dystrophy candidate gene FRG1 is critical for muscle development". Developmental Dynamics. 238

over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The expression of psoriasin is

July 30, 2019. Harris, Keith (August 13, 2020). "GOP congressional candidate Gene Rechtzigel's website is... something else". City Pages. Retrieved August

A, Cummings JR, Morris A, Cooney R, et al. (April 2008). "Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous

PMID 16205629. Aberg K, Saetre P, Lindholm E, et al. (2006). "Human QKI, a new candidate gene for schizophrenia involved in myelination". Am. J. Med. Genet. B Neuropsychiatr

structure, and expression profiles of TULIP1 (GARNL1), a brain-expressed candidate gene for 14q13-linked neurological phenotypes, and its murine homologue"

expression levels, identify potential polyadenylation sites, as well as candidate gene-fusion events. Trinity first divides the sequence data into a number

Alagaratnam S, Hardy JR, Lothe RA, Skotheim RI, Byrne JA (2008). "TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours"

genes from proteins previously described via animal knockout models and candidate gene analysis. Instead, large percentages of genes involved in processes

PMID 1574589. Vieira AR, McHenry TG, Daack-Hirsch S, et al. (2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

disease genes using genome-wide linkage analysis, positional cloning, candidate gene resequencing, genome-wide association analyses and epigenetic assays

Dierks C, Hamann H, Distl O (March–April 2008). "Associations between candidate gene markers at a quantitative trait locus on equine chromosome 4 responsible

associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]. GRCh38: Ensembl release

Soria JM, et al. (2005). "A Genomewide Exploration Suggests a New Candidate Gene at Chromosome 11q23 as the Major Determinant of Plasma Homocysteine

DJ, Patterson RH, et al. (2004). "Analysis of Sciellin (SCEL) as a candidate gene in esophageal squamous cell carcinoma". Anticancer Res. 24 (3a): 1417–9

Associated With Glycine Receptor GLRA1 Polymorphism: An Exploratory Candidate-Gene Association Study". Journal of Personality Disorders. 32 (3): 421–432

predispose for statin-induced myopathy. This gene also represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver

sought and received re-election to his fifth term, defeating Republican candidate Gene Knorr. Only Burdick filed as a Dem-NPLer, and the endorsed Republican

to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene. [provided by RefSeq, Jul 2008]. GRCh38: Ensembl release 89: ENSG00000134815

Bhasin N, et al. (2002). "RanBP1, a velocardiofacial/DiGeorge syndrome candidate gene, is expressed at sites of mesenchymal/epithelial induction". Mech. Dev

(2000). Bertsch, B. et al., Convergent functional genomics: a Bayesian candidate gene identification approach for complex disorders. Methods 37 (3), 274 (2005)

Seldin MF, Gregersen PK, Criswell LA, Barcellos LF (September 2010). "A candidate gene study of CLEC16A does not provide evidence of association with risk

ability to create and sequence genomic libraries. Prior, linkage and candidate-gene studies were some of the only approaches. Construction of a genomic

Virtanen I, Peltonen L, Olkkonen VM (Aug 2009). "OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates

SMITH, R. J. H.; JACKSON, C. L. (May 2000). "2E4/Kaptin (KPTN) – a candidate gene for the hearing loss locus, DFNA4". Annals of Human Genetics. 64 (Pt

cancer and implicated the proteasome subunit alpha type-4 (PMSA4) as a candidate gene. A case-control study in lung cancer patients and controls in the Chinese

cancer and implicated the proteasome subunit alpha type-4 (PMSA4) as a candidate gene. A case-control study in lung cancer patients and controls in the Chinese

identification of shared disease haplotypes, and exclusion of TPST1 as a candidate gene". European Journal of Human Genetics. 10 (4): 250–8. doi:10.1038/sj

AUTS2 gene. This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders

Davis DB, Delmonte AJ, Ly CT, McNally EM (Feb 2000). "Myoferlin, a candidate gene and potential modifier of muscular dystrophy". Hum Mol Genet. 9 (2):

Kazi M, Wilson JG, Subauste JS, Cowan BD (December 2005). "FEM1A is a candidate gene for polycystic ovary syndrome". Gynecol. Endocrinol. 21 (6): 330–5.

ARHGEF6, a guanine nucleotide exchange factor for Rho GTPases and a candidate gene for X-linked mental retardation: mutation screening in Börjeson-Forssman-Lehmann

Hewitt JE, et al. (2003). "Identification of the autoantigen SART-1 as a candidate gene for the development of atopy". Hum. Mol. Genet. 11 (18): 2143–6. doi:10

K, Kinnula V, Kere J, Tukiainen P, Laitinen T (2006). "ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis". Am. J. Hum. Genet. 79 (1):

characterization of a novel cochlear gene in human and in mouse: a positional candidate gene for a deafness disorder, DFNA9". Genomics. 46 (3): 345–54. doi:10.1006/geno

Heuts-Vijgen R, Stegmann AP, Smeets EE, Engelen JJ (2011). "MYT1L is a candidate gene for intellectual disability in patients with 2p25.3 (2pter) deletions"

Klauck SM, Poustka F, Bailey AJ, Monaco AP (Sep 2010). "Linkage and candidate gene studies of autism spectrum disorders in European populations". European

"Point: population stratification: a problem for case-control studies of candidate-gene associations?". Cancer Epidemiology, Biomarkers & Prevention. 11 (6):

WC, Nelson RG, Wolford JK (April 2007). "Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based

antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension". Proceedings of the National Academy of

a cosmid from a gene-rich region in 17q21 and characterization of a candidate gene for alpha-N-acetylglucosaminidase with two cDNA isoforms". Mammalian

increased in a rat model of spinal cord injury. PAK6 is also considered a candidate gene for epileptic encephalopathy, and interacts with Parkinson associated

with 30.7% of the vote, defeating six other candidates. Libertarian candidate Gene Siadek also appeared on the general election ballot. After the primary

phenotypic data. Researchers who wish to link the ELSA GWAS or existing candidate gene polymorphisms with ELSA phenotypic data are required to submit a full

usually obtained from genome-wide association studies though can also be candidate gene studies. The second assumption relies on there being no population substructure

Leptinotarsa decemlineata: Sex Chromosomes and a Pyrethroid-Resistance Candidate Gene. Genetics 158: 695-700 Mitman, Gregg (1992). The State of Nature: Ecology

Vincent A, Willcox N, Kleta R, Fischbeck KH, Burnett BG (2012). "A candidate gene for autoimmune myasthenia gravis". Neurology. 79 (4): 342–7. doi:10

J., Lammer, E. J., Iovannisci, D. M., Glidden, D. V., et al.(2006). Candidate Gene Polymorphisms Do Not Differ Between Newborns With Stroke and Normal

et al. (2009). "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease". Mol. Psychiatry. 14 (11): 1004–16. doi:10

of the results is gene set enrichment analysis, although sometimes candidate gene approaches are employed. Gene set enrichment determines if the overlap

2007 Dixit M, Ansseau E, Tassin A, et al. (November 2007). "DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional

Jongh GJ, et al. (2003). "The human cystatin M/E gene (CST6): exclusion candidate gene for harlequin ichthyosis". J. Invest. Dermatol. 121 (1): 65–8. doi:10

Keller MC (October 2011). "A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry". The American Journal

genome-wide scan (in conjunction with investigators at Oxford University), candidate gene investigations, and a series of papers on ADHD among a northern Finnish

McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

encoding an E3 ubiquitin-protein ligase, was identified as the most likely candidate gene, with two protein-truncating mutations in probands in the first family

Möhlig M, Hampe J, Schreiber S, Schrezenmeir J, Döring F (Feb 2007). "Candidate gene association study of type 2 diabetes in a nested case-control study

10q24.1-q24.3 encoding the beta-O-linked N-acetylglucosaminidase as a candidate gene for type 2 diabetes mellitus in Pima Indians". Molecular Genetics and

JC (2009). "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease". Mol. Psychiatry. 14 (11): 1004–16. doi:10

McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

Table 2, pp. 156–157), the phenotype of the individual possessing the candidate gene mutation includes "chronic lung disease". However, chronic lung—or chronic

Tanyolac, K.D. Livingstone, S. Popovsky, I. Paran and M.M. Jahn. (2000) Candidate gene analysis of organ pigmentation loci in the Solanaceae. Proc. Natl. Acad

(April 2017). "Thermal tolerance in the keystone species Daphnia magna—a candidate gene and an outlier analysis approach" (PDF). Molecular Ecology. 26 (8):

candidate genes that may be responsible for neural induction.  One such candidate gene, noggin, is sufficient for rescuing development of irradiated embryos

was analyzed in Restless Leg Syndrome, but was not identified as a candidate gene. One study examined the role of Drosophila KIBRA (WWC1) in the Expanded-Hippo-Warts

Pettersson U, Adolfsson R, Jazin E (January 2006). "Human QKI, a new candidate gene for schizophrenia involved in myelination". American Journal of Medical

Letourneur F, Cagnard N, Izac B, Vigier A, et al. (July 2011). "Systematic candidate gene investigations in the SPA2 locus (9q32) show an association between

PMID 18523156. Ferrell RE, Kimak MA, Lawrence EC, Finegold DN (2008). "Candidate gene analysis in primary lymphedema". Lymphatic Research and Biology. 6 (2):

addition, work with the Lanzer group led to the identification of a candidate gene for quinine and quinidine resistance. With his son Moshe Hoshen, together

(November 2009). "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease". Molecular Psychiatry. 14 (11): 1004–1016.

genomic structure, chromosomal localization, and analysis of SIL as a candidate gene for holoprosencephaly". Cytogenet. Genome Res. 97 (1–2): 62–7. doi:10

Partecke, J.; Hatchwell, B. J.; Gaston, K. J.; Evans, K. L. (July 2013). "Candidate gene polymorphisms for behavioural adaptations during urbanization in blackbirds"

"Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A". Genetics. 163 (2, February): 571–580. doi:10.1093/genetics/163

associated by EMASS (EU funded, PI McGuffin), the first multicentre candidate gene association study of its type. McGuffin subsequently led genome wide

genomic structure, chromosomal localization, and analysis of SIL as a candidate gene for holoprosencephaly". Cytogenet. Genome Res. 97 (1–2): 62–7. doi:10

: 231  It was later substantiated by Susumu Ohno, who identified a candidate gene that may have arisen by this mechanism. Some de novo genes originating

Nemens, E; Wejsman, EM; Bird, TD; Schellenberg, GD; Tanzi, RE (1995). "Candidate gene for the chromosome 1 familial Alzheimer's disease locus". Science. 269

processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease". Proc. Natl. Acad. Sci. U.S.A. 103

left ventricle of the heart. The MFSD6L gene was also found to be a candidate gene taking part in the disease Pediatric Cataract. Various SNP's were found

"Chromosomal assignment of the canine melanophilin gene (MLPH): a candidate gene for coat color dilution in Pinschers". Journal of Heredity. 96 (7):

Gamble D, Hardy JA, Rich SS, Singleton A, Meschia JF (Nov 2009). "Candidate gene polymorphisms for ischemic stroke". Stroke: A Journal of Cerebral Circulation

Cormand B (2020-01-01). "RBFOX1, encoding a splicing regulator, is a candidate gene for aggressive behavior". European Neuropsychopharmacology. Neurobiology

Kathie; Aggarwal, Vimla; South, Sarah T. (February 2014). "SNX8: A candidate gene for 7p22 cardiac malformations including tetralogy of fallot". American

heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations". Stroke. 43 (12): 3161–3167. doi:10.1161/STROKEAHA

Nemens, E; Wijsman, EM; Bird, TD; Schellenberg, GD; Tanzi, RE (1995). "Candidate gene for the chromosome 1 familial Alzheimer's disease locus". Science. 269

inheritance. positional cloning A strategy for identifying and cloning a candidate gene based on knowledge of its locus or position alone and with little or

Einarsdottir E, Simony A, Danielsson A, Åkesson K, et al. (October 2015). "Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene

"Transcriptional deregulation and a missense mutation define ANKRD1 as a candidate gene for total anomalous pulmonary venous return". Human Mutation. 29 (4):

Uhlmann A, Nday CM, Glatt SJ, Mitt M, Metsalpu A, et al. (May 2016). "Candidate gene networks and blood biomarkers of methamphetamine-associated psychosis:

McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility

identifies novel mutations in ACTB, and SLC9A6, and suggests BAZ1A as a new candidate gene". Birth Defects Research. 110 (7): 587–597. doi:10.1002/bdr2.1200. hdl:21

Parkinson's disease, which can be useful for monitoring the disease. Candidate gene alleles causative of Alzheimer's disease and elderly dementia where

"Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility." J Biol Chem. 2004 April 16;279(16):16121-7

germplasm against gall nematode, Fusarium wilt disease and development of candidate gene markers". 1998 – ″Umid″ Foundation Scholarship to study at Texas A&M

Tsui, L.C. (November 1, 1996). "Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly". Nature Genetics. 14 (3): 353–356

for use in fine mapping of the PFHBI gene and screening of the HRC candidate gene (Thesis) – via scholar.sun.ac.za. Christoffels, Alan (August 29, 2001)

Delphine; Pulcini, Françoise; Weissenbach, Jean (September 1997). "A candidate gene for familial Mediterranean fever". Nature Genetics. 17 (1): 25–31. doi:10

Changes in VPS35 affect levels of leucine-rich repeat kinase 2 (LRRK2), a candidate gene involved in PD that helps vesicular trafficking by phosphorylating Rab

involved in these traits. To achieve this, the so-called positional candidate gene approach is gaining in importance. This approach is based on the genetic

colleagues at the Imperial Cancer Research Fund in London, discovered a new candidate gene, Sry. Koopman and colleagues injected Sry into fertilized XX mouse eggs

that are co-regulated within or across cell types, as well as discover candidate gene targets for treating specific neurological disorders and screen for

structure and function of cMyBP-C. MYBPC3 became therefore the “best” candidate gene for the CMH4 locus for hypertrophic cardiomyopathy that was initially

summary data extracted from published papers in peer reviewed journals on candidate gene and genome Wide Association Studies (GWAS). The GAD was frozen as of

manual inspection of ribosome profiling traces None None 1 de novo candidate gene, 217 ribosome-associated transcripts Candidate de novo gene is polymorphic

The explanation for this association remains to be determined. In a candidate gene studies, associations with IFNL4 genotype have been reported for prostate

Pompili V, Singh J, Micheletti D, Silva JK, Malnoy M, Khan MA. 2020. Candidate gene mapping identifies genomic variations in the fire blight susceptibility