Find link

language:

jump to random article

Find link is a tool written by Edward Betts.

Longer titles found: Histone-arginine N-methyltransferase (view), Histone-like nucleoid-structuring protein (view), Histone-modifying enzymes (view), Histone 3′ UTR stem-loop (view), Histone Database (view), Histone H1 (view), Histone H2A (view), Histone H2A.Z (view), Histone H2B (view), Histone H2B type 1-C (view), Histone H3 (view), Histone H4 (view), Histone acetylation and deacetylation (view), Histone acetyltransferase (view), Histone cluster 2 h3 family member d (view), Histone code (view), Histone deacetylase (view), Histone deacetylase 2 (view), Histone deacetylase 5 (view), Histone deacetylase inhibitor (view), Histone demethylase (view), Histone fold (view), Histone methylation (view), Histone methyltransferase (view), Histone octamer (view), Histone variants (view), Anti-histone antibodies (view), Non-histone protein (view), (Histone-H3)-lysine-36 demethylase (view), Linker histone H1 variants (view), ASF1 like histone chaperone (view), NuA4 histone acetyltransferase complex (view), Alkb homolog 1, histone h2a dioxygenase (view)

searching for Histone 200 found (2137 total)

alternate case: histone

JARID1B (1,061 words) [view diff] exact match in snippet view article find links to article

Lysine-specific demethylase 5B also known as histone demethylase JARID1B is a demethylase enzyme that in humans is encoded by the KDM5B gene. JARID1B
JADE1 (5,937 words) [view diff] exact match in snippet view article find links to article
recognize and bind specific methylated lysine of histone H3, which defined these domains as epigenetic histone code readers. Reviews describing structure and
KDM5A (1,597 words) [view diff] exact match in snippet view article find links to article
found for this gene. The Drosophila homolog, LID, was found to be an H3K4 histone demethylase that binds to c-Myc. It was recently renamed to Lysine Demethylase
HMGN2 (845 words) [view diff] exact match in snippet view article find links to article
Non-histone chromosomal protein HMG-17 is a protein that in humans is encoded by the HMGN2 gene. High mobility group protein HMG14 and HMG17 HMGN1 (HMG-14)
PHF20 (326 words) [view diff] exact match in snippet view article find links to article
histone acetyltransferase activity (H4-K8 specific) • DNA binding • histone acetyltransferase activity (H4-K5 specific) • metal ion binding • histone
KDM5C (837 words) [view diff] exact match in snippet view article find links to article
"The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases". Cell. 128 (6): 1077–88. doi:10.1016/j.cell.2007
KMT2C (1,125 words) [view diff] exact match in snippet view article find links to article
protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. Alternate
PHF16 (587 words) [view diff] exact match in snippet view article find links to article
histone acetyltransferase complex Biological process • histone H4-K16 acetylation • histone H4-K8 acetylation • histone H4-K12 acetylation • histone H3
KDM5D (1,065 words) [view diff] exact match in snippet view article find links to article
"The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases". Cell. 128 (6): 1077–88. doi:10.1016/j.cell.2007
POLE3 (564 words) [view diff] exact match in snippet view article find links to article
POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein
ING4 (1,422 words) [view diff] exact match in snippet view article find links to article
remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent
MEF2D (1,257 words) [view diff] exact match in snippet view article find links to article
MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2". Immunity. 13 (1): 85–94. doi:10
Major histocompatibility complex (5,903 words) [view diff] no match in snippet view article find links to article
The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface
Testicular receptor 2 (922 words) [view diff] exact match in snippet view article find links to article
PMID 12093804. Li G, Franco PJ, Wei LN (Oct 2003). "Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2"
RPS6KA4 (640 words) [view diff] exact match in snippet view article find links to article
"MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14". EMBO J. 22 (11): 2788–2797. doi:10.1093/emboj/cdg273. PMC 156769
ING2 (952 words) [view diff] exact match in snippet view article find links to article
ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair
Bryan M. Turner (235 words) [view diff] exact match in snippet view article find links to article
the histone marks. These novel tools allowed him to link histone deacetylation to gene silencing via the discovery that chromosome-wide histone deacetylation
ING2 (952 words) [view diff] exact match in snippet view article find links to article
ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair
NFYB (1,190 words) [view diff] exact match in snippet view article find links to article
specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of
JARID2 (1,474 words) [view diff] exact match in snippet view article find links to article
regulatory region sequence-specific DNA binding • chromatin binding • histone demethylase activity • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription
SIN3B (1,090 words) [view diff] exact match in snippet view article find links to article
Bird A, Reinberg D (Aug 1999). "Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation". Genes
HR (gene) (1,037 words) [view diff] exact match in snippet view article
as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Variations in this gene are involved in low levels of hair
MEF2B (1,153 words) [view diff] exact match in snippet view article find links to article
Goya R, Mungall KL, Corbett RD, et al. (Aug 2011). "Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma" (PDF). Nature. 476 (7360): 298–303
GFI1 (1,241 words) [view diff] exact match in snippet view article find links to article
Epigenetic Repression of p21Cip/WAF1 by Recruitment of Histone Lysine Methyltransferase G9a and Histone Deacetylase 1". Mol. Cell. Biol. 25 (23): 10338–51
PHF1 (432 words) [view diff] exact match in snippet view article find links to article
DNA-binding transcription factor activity • metal ion binding • methylated histone binding • GO:0001948 protein binding • chromatin binding • nucleosome binding
ING1 (1,390 words) [view diff] exact match in snippet view article find links to article
D, Riabowol K (Aug 2002). "Human ING1 proteins differentially regulate histone acetylation". The Journal of Biological Chemistry. 277 (33): 29832–9. doi:10
Polyuridylation (96 words) [view diff] exact match in snippet view article find links to article
group of RNAs that can be polyuridylated are histone mRNAs that lack a poly(A) tail. Polyuridylation of a histone mRNA promotes its degradation, involving
MTA1 (3,900 words) [view diff] exact match in snippet view article find links to article
revealed the role of MTA1 in interactions with modified or unmodified histone and non-histone proteins, chromatin remodeling, and modulation of gene transcription
Computational epigenetics (1,204 words) [view diff] exact match in snippet view article find links to article
The Histone Database Contains 254 sequences from histone H1, 383 from histone H2, 311 from histone H2B, 1043 from histone H3 and 198 from histone H4,
KAT8 regulatory NSL complex subunit 1 (689 words) [view diff] exact match in snippet view article find links to article
histone acetyltransferase activity (H4-K5 specific) • histone acetyltransferase activity (H4-K16 specific) • GO:0001948 protein binding • histone acetyltransferase
CTBP1 (2,213 words) [view diff] exact match in snippet view article find links to article
help turn genes off. CtBPs do this by recruiting histone modifying enzymes that add repressive histone marks and remove activating marks. CtBP proteins
HIST2H3C (1,120 words) [view diff] exact match in snippet view article find links to article
Histone H3.2 is a protein that in humans is encoded by the HIST2H3C gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
ATM serine/threonine kinase (4,933 words) [view diff] exact match in snippet view article find links to article
together. ATM directly interacts with the NBS1 subunit and phosphorylates the histone variant H2AX on Ser139. This phosphorylation generates binding sites for
RBBP7 (1,711 words) [view diff] exact match in snippet view article find links to article
Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene. This protein is a ubiquitously expressed nuclear protein and belongs
KAT8 regulatory NSL complex subunit 1 (689 words) [view diff] exact match in snippet view article find links to article
histone acetyltransferase activity (H4-K5 specific) • histone acetyltransferase activity (H4-K16 specific) • GO:0001948 protein binding • histone acetyltransferase
ATM serine/threonine kinase (4,933 words) [view diff] exact match in snippet view article find links to article
together. ATM directly interacts with the NBS1 subunit and phosphorylates the histone variant H2AX on Ser139. This phosphorylation generates binding sites for
Lepidopsocidae (304 words) [view diff] exact match in snippet view article find links to article
partial sequences of the nuclear 18S rDNA, mitochondrial 16S rDNA, and Histone 3 genes, propose that Lepidopsocidae is monophyletic, meaning that the
KDM4A (1,559 words) [view diff] exact match in snippet view article find links to article
trimethylation-specific demethylase, converting specific trimethylated histone on histone H3 lysine 9 and 36 residues to the dimethylated form and lysine 9
MEF2C (1,870 words) [view diff] exact match in snippet view article find links to article
Crosato M, Heng HH, Th'ng J, Han J, Yang XJ (Nov 1999). "HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor". Molecular
KDM3B (625 words) [view diff] exact match in snippet view article find links to article
ion binding • histone demethylase activity • transcription regulatory region sequence-specific DNA binding • chromatin DNA binding • histone demethylase
WDR5 (1,107 words) [view diff] exact match in snippet view article find links to article
Michael L (Jul 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression".
SUZ12 (1,202 words) [view diff] exact match in snippet view article find links to article
Lopez-Corrales N, Cibelli JB (December 2008). "Polycomb gene expression and histone H3 lysine 27 trimethylation changes during bovine preimplantation development"
HIST1H4I (927 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that, in humans, is encoded by the HIST1H4I gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
SETD7 (652 words) [view diff] exact match in snippet view article find links to article
Histone-lysine N-methyltransferase SETD7 is an enzyme that in humans is encoded by the SETD7 gene. GRCh38: Ensembl release 89: ENSG00000145391 - Ensembl
H3F3A (1,295 words) [view diff] exact match in snippet view article find links to article
Histone H3.3 is a protein that in humans is encoded by the H3F3A and H3F3B genes. It plays an essential role in maintaining genome integrity during mammalian
SETDB1 (1,614 words) [view diff] exact match in snippet view article find links to article
Histone-lysine N-methyltransferase SETDB1 is an enzyme that in humans is encoded by the SETDB1 gene.SETDB1 is also known as KMT1E or H3K9 methyltransferase
ZBTB33 (1,133 words) [view diff] exact match in snippet view article find links to article
zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target
CDY1 (741 words) [view diff] exact match in snippet view article find links to article
where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the
HIST2H2BE (1,142 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 2-E is a protein that in humans is encoded by the HIST2H2BE gene. Histones are basic nuclear proteins that are responsible for the nucleosome
Sp2 transcription factor (792 words) [view diff] exact match in snippet view article find links to article
involvement of specificity protein-1 (Sp1), Sp3, Sp4, Sp-like proteins, and histone deacetylases". J. Clin. Endocrinol. Metab. 90 (6): 3479–90. doi:10.1210/jc
ZBTB33 (1,133 words) [view diff] exact match in snippet view article find links to article
zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target
HIST1H2AE (907 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1-B/E is a protein that in humans is encoded by the HIST1H2AE gene. Histones are basic nuclear proteins that are responsible for the
2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate (311 words) [view diff] exact match in snippet view article find links to article
oxidative stress, MEcPP accumulates in certain bacteria. MEcPP releases histone-like proteins from DNA, triggering nucleoid decondensation in Chlamydia
Lymphoid enhancer-binding factor 1 (1,611 words) [view diff] exact match in snippet view article find links to article
DNA-binding transcription activator activity, RNA polymerase II-specific • histone deacetylase binding • armadillo repeat domain binding • estrogen receptor
SnRNP (1,800 words) [view diff] exact match in snippet view article find links to article
at all, as U7 snRNP is responsible for processing the 3′ stem-loop of histone pre-mRNA. The two essential components of snRNPs are protein molecules
FOXP3 (3,318 words) [view diff] exact match in snippet view article find links to article
depending on what specific transcriptional factors such as deacetylases and histone acetylases are acting on it. The Foxp3 gene is also known to convert naïve
KAT8 (923 words) [view diff] exact match in snippet view article find links to article
enzyme that in humans is encoded by the KAT8 gene. The MYST family of histone acetyltransferases, which includes KAT8, was named for the founding members
Protein kinase N1 (1,741 words) [view diff] exact match in snippet view article find links to article
binding • protein kinase C activity • histone binding • histone deacetylase binding • chromatin binding • histone kinase activity (H3-T11 specific) • kinase
HIST1H2BB (909 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-B is a protein that in humans is encoded by the HIST1H2BB gene. Histones are basic nuclear proteins that are responsible for the nucleosome
EZH1 (688 words) [view diff] exact match in snippet view article find links to article
Histone-lysine N-methyltransferase EZH1 is an enzyme that in humans is encoded by the EZH1 gene. In mice, EZH1 and EZH2 cogovern histone H3K27 trimethylation
MCM2 (1,585 words) [view diff] exact match in snippet view article find links to article
(Sep 1996). "Binding of human minichromosome maintenance proteins with histone H3". J. Biol. Chem. 271 (39): 24115–22. doi:10.1074/jbc.271.39.24115. PMID 8798650
HIST1H2BL (848 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-L is a protein that in humans is encoded by the HIST1H2BL gene. Histones are basic nuclear proteins that are responsible for the nucleosome
HIST1H2BJ (897 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-J is a protein that in humans is encoded by the HIST1H2BJ gene. Histones are basic nuclear proteins that are responsible for the nucleosome
HIST1H2BG (919 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-C/E/F/G/I is a protein that in humans is encoded by the HIST1H2BG gene. Histones are basic nuclear proteins that are responsible for
HIST1H4D (566 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4D gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
KAT6B (980 words) [view diff] exact match in snippet view article find links to article
Vezmar M, Yang Y, Heng HH, Yang XJ (Nov 1999). "Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein". J
ASF1A (1,213 words) [view diff] exact match in snippet view article find links to article
Histone chaperone ASF1A is a protein that in humans is encoded by the ASF1A gene. This gene encodes a member of the H3/H4 family of histone chaperone
ZBTB32 (1,640 words) [view diff] exact match in snippet view article find links to article
immune cell tumorigenesis or immune cell development. The protein recruits histone modification enzymes to chromatin to affect gene activation. ZBTB32 recruits
HIST1H3E (587 words) [view diff] exact match in snippet view article find links to article
Histone H3.1 is a protein that in humans is encoded by the HIST1H3E gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
HIST1H4A (675 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4A gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
HIST1H2AA (678 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1-A is a protein that in humans is encoded by the HIST1H2AA gene. Histones are basic nuclear proteins that are responsible for the nucleosome
HIST2H3PS2 (770 words) [view diff] exact match in snippet view article find links to article
Histone cluster 2, H3, pseudogene 2, also known as HIST2H3PS2, is a human gene. GRCh38: Ensembl release 89: ENSG00000273213 - Ensembl, May 2017 "Human
ASH2L (733 words) [view diff] exact match in snippet view article find links to article
Set1/Ash2 histone methyltransferase complex subunit ASH2 is an enzyme that in humans is encoded by the ASH2L gene. ASH2L has been shown to interact with
HIST2H4A (976 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST2H4A gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
HIST1H1B (908 words) [view diff] exact match in snippet view article find links to article
Histone H1.5 is a protein that in humans is encoded by the HIST1H1B gene. Histones are basic nuclear proteins responsible for nucleosome structure of the
RBBP5 (855 words) [view diff] exact match in snippet view article find links to article
Cleary ML (Jul 2004). "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression".
HIST1H4B (511 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4B gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
HIST1H2BD (920 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-D is a protein that in humans is encoded by the HIST1H2BD gene. Histones are basic nuclear proteins that are responsible for the nucleosome
HIST1H1E (724 words) [view diff] exact match in snippet view article find links to article
Histone H1.4 is a protein that in humans is encoded by the HIST1H1E gene. Histones are basic nuclear proteins responsible for nucleosome structure of the
HIST1H3G (511 words) [view diff] exact match in snippet view article find links to article
Histone H3.1 is a protein that in humans is encoded by the HIST1H3G gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
UBE2B (961 words) [view diff] exact match in snippet view article find links to article
ubiquitination • histone lysine demethylation • protein K48-linked ubiquitination • negative regulation of histone phosphorylation • regulation of histone modification
TNP2 (508 words) [view diff] exact match in snippet view article find links to article
21039–47. PMID 2250010. "Entrez Gene: TNP2 transition protein 2 (during histone to protamine replacement)". Schlüter G, Kremling H, Engel W (1992). "The
HIST1H4F (788 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4F gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
HIST2H2BF (396 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 2-F is a protein that in humans is encoded by the HIST2H2BF gene. GRCh38: Ensembl release 89: ENSG00000203814 - Ensembl, May 2017 "Human
NSD1 (296 words) [view diff] exact match in snippet view article find links to article
SET Domain Protein 1)is a transcription coregulator protein that encodes Histone Methyltransferase and is associated with Sotos syndrome and Weaver syndrome
HIST1H3A (856 words) [view diff] exact match in snippet view article find links to article
Histone H3.1 is a protein that in humans is encoded by the HIST1H3A gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
MAPK8 (1,683 words) [view diff] exact match in snippet view article find links to article
1995). "Neither ERK nor JNK/SAPK MAP kinase subtypes are essential for histone H3/HMG-14 phosphorylation or c-fos and c-jun induction". J. Cell Sci. 108
PRMT6 (587 words) [view diff] exact match in snippet view article find links to article
PMID 17267505. Guccione E, Bassi C, Casadio F, et al. (2007). "Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive". Nature
HIST1H4E (458 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4E gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
EIF3A (1,354 words) [view diff] exact match in snippet view article find links to article
dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities". Cell. 95 (2): 279–89
Exonuclease (1,319 words) [view diff] exact match in snippet view article find links to article
type endonuclease is known to be essential for the proper processing of histone pre-mRNA, in which U7 snRNP directs the single cleavage process. Following
KAT6A (968 words) [view diff] exact match in snippet view article find links to article
Information, U.S. National Library of Medicine. "Entrez Gene: MYST3 MYST histone acetyltransferase (monocytic leukemia) 3". Borrow J, Stanton VP, Andresen
HIST1H2BH (810 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-H is a protein that in humans is encoded by the HIST1H2BH gene. Histones are basic nuclear proteins that are responsible for the nucleosome
HIST1H1D (677 words) [view diff] exact match in snippet view article find links to article
Histone H1.3 is a protein that in humans is encoded by the HIST1H1D gene. Histones are basic nuclear proteins responsible for nucleosome structure of the
Cyclin-dependent kinase 9 (1,261 words) [view diff] exact match in snippet view article find links to article
promoter • phosphorylation • positive regulation of histone phosphorylation • positive regulation of histone H2B ubiquitination • Socialize Africa • transcription
Twist transcription factor (2,265 words) [view diff] exact match in snippet view article find links to article
Puri PL, Wu HY, Wang JY, Nakatani Y, Kedes L (Feb 1999). "Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral
Kruppel-like factors (2,098 words) [view diff] exact match in snippet view article find links to article
and 2. CtBP in turn recruits histone modifying enzymes. It brings in histone deacetylases, histone demethylases and histone methylases, which are thought
RE1-silencing transcription factor (2,007 words) [view diff] exact match in snippet view article find links to article
(November 1999). "Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specific target genes". Proceedings
HIST1H4H (472 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4H gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
PRKCB1 (668 words) [view diff] exact match in snippet view article find links to article
nucleotide binding • protein kinase activity • protein kinase C activity • histone binding • zinc ion binding • calcium channel regulator activity • chromatin
HIST1H2BF (553 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-C/E/F/G/I is a protein that in humans is encoded by the HIST1H2BF gene. Histones are basic nuclear proteins that are responsible for
CAMK1 (973 words) [view diff] exact match in snippet view article find links to article
Zhang CL, Lu J, Olson EN (2000). "Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation". Nature. 408 (6808): 106–11
MEAF6 (625 words) [view diff] exact match in snippet view article find links to article
"Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex". J Biol Chem. 278 (44): 42733–6. doi:10.1074/jbc
HIST1H1C (766 words) [view diff] exact match in snippet view article find links to article
Histone H1.2 is a protein that in humans is encoded by the HIST1H1C gene. Histones are basic nuclear proteins responsible for nucleosome structure of the
MBD3 (1,442 words) [view diff] exact match in snippet view article find links to article
remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase
HIST4H4 (922 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST4H4 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
RNF20 (844 words) [view diff] exact match in snippet view article find links to article
a ubiquitin ligase required for the ubiquitination of histone H2B and the methylation of histone H3. RING finger domain GRCh38: Ensembl release 89: ENSG00000155827
HIST1H2BN (835 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-N is a protein that in humans is encoded by the HIST1H2BN gene. Histones are basic nuclear proteins that are responsible for the nucleosome
HIST3H3 (976 words) [view diff] exact match in snippet view article find links to article
Histone H3.1t is a protein that in humans is encoded by the HIST3H3 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
Cyclin D1 (5,697 words) [view diff] exact match in snippet view article find links to article
proliferation, growth, and differentiation. Cyclin D1 also binds to histone acetylases and histone deacetylases to regulate cell proliferation and cell differentiation
USP22 (520 words) [view diff] exact match in snippet view article find links to article
chromosome 17. USP22 is known to function as a histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. GRCh38:
Acute myeloblastic leukemia with maturation (3,120 words) [view diff] exact match in snippet view article find links to article
2005). DEK functions as a transcriptional repressor by interfering with histone acetyl transferases, regulator for a number of stem cells, and activates
HIST1H1A (902 words) [view diff] exact match in snippet view article find links to article
Histone H1.1 is a protein that in humans is encoded by the HIST1H1A gene. Histones are basic nuclear proteins responsible for nucleosome structure of the
ASF1B (775 words) [view diff] exact match in snippet view article find links to article
Histone chaperone ASF1B is a protein that in humans is encoded by the ASF1B gene. This gene encodes a member of the H3/H4 family of histone chaperone
SAP18 (684 words) [view diff] exact match in snippet view article find links to article
Histone deacetylase complex subunit SAP18 is an enzyme that in humans is encoded by the SAP18 gene. Histone acetylation plays a key role in the regulation
ORC1 (1,381 words) [view diff] exact match in snippet view article find links to article
phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MYST2/HBO1), a protein involved in control of transcription
H1FX (581 words) [view diff] exact match in snippet view article find links to article
Histone H1x is a protein that in humans is encoded by the H1FX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
HIST1H4G (462 words) [view diff] exact match in snippet view article find links to article
Histone H4-like protein type G is a protein that in humans is encoded by the HIST1H4G gene. Histones are basic nuclear proteins that are responsible for
KDM4B (536 words) [view diff] exact match in snippet view article find links to article
Nottke A, Lan F, et al. (2006). "Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases". Cell. 125 (3): 467–81. doi:10
Receptor modulator (46 words) [view diff] exact match in snippet view article find links to article
modulators Others and non-receptor Enzymes: Cytochrome P450 modulators Histone deacetylase inhibitors Phosphodiesterase inhibitors Ion channels: Ion channel
HIST1H3D (512 words) [view diff] exact match in snippet view article find links to article
Histone H3.1 is a protein that in humans is encoded by the HIST1H3D gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
KDM4C (1,012 words) [view diff] exact match in snippet view article find links to article
trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased
WHSC1L1 (620 words) [view diff] exact match in snippet view article find links to article
Histone-lysine N-methyltransferase NSD3 is an enzyme that in humans is encoded by the WHSC1L1 gene. This gene is related to the Wolf-Hirschhorn syndrome
HIST1H3J (479 words) [view diff] exact match in snippet view article find links to article
Histone H3.1 is a protein that in humans is encoded by the HIST1H3J gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
Protein phosphorylation (7,359 words) [view diff] exact match in snippet view article find links to article
certain enzymes and proteins. Post-translational modification of histones such as histone phosphorylation has been shown to modify the chromatin structure
NFYA (1,379 words) [view diff] exact match in snippet view article find links to article
AE, Cinghu S, Freudenberg JM, Yellaboina S, Jothi R (September 2014). "Histone-fold domain protein NF-Y promotes chromatin accessibility for cell type-specific
HIST1H4C (529 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4C gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
C-Fos (3,872 words) [view diff] exact match in snippet view article find links to article
which induces its association with the histone acetyltransferase, CREB binding protein (CBP) to acetylate histones and facilitate gene activation. This
MORF4L1 (1,016 words) [view diff] exact match in snippet view article find links to article
"Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex". The Journal of Biological Chemistry. 278 (44):
Mef2 (1,568 words) [view diff] exact match in snippet view article find links to article
factors shows member-specific features and mediates the nuclear import of histone deacetylase 4". J Cell Sci. 114 (Pt 24): 4477–83. PMID 11792813. Yu YT
DMAP1 (1,080 words) [view diff] exact match in snippet view article find links to article
methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive
MAPK3 (1,148 words) [view diff] exact match in snippet view article find links to article
X, Richon VM, Wang AH, Yang XJ, Rifkind RA, Marks PA (December 2000). "Histone deacetylase 4 associates with extracellular signal-regulated kinases 1
SUV420H1 (668 words) [view diff] exact match in snippet view article find links to article
Histone-lysine N-methyltransferase SUV420H1 is an enzyme that in humans is encoded by the SUV420H1 gene. The enzyme along with WHSC1 is responsible for
HIST1H4K (396 words) [view diff] exact match in snippet view article find links to article
Histone H4 is a protein that in humans is encoded by the HIST1H4K gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure
SUV39H2 (542 words) [view diff] exact match in snippet view article find links to article
Histone-lysine N-methyltransferase SUV39H2 is an enzyme that in humans is encoded by the SUV39H2 gene. GRCh38: Ensembl release 89: ENSG00000152455 - Ensembl
TAF6L (770 words) [view diff] exact match in snippet view article find links to article
component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which
TRIM28 (2,240 words) [view diff] exact match in snippet view article find links to article
genome. The protein binds to the histones of the viral chromatin and then recruits Mi2α and SETB1. SETB1 is a histone methyltransferase that recruits HP1
Arrestin beta 1 (1,458 words) [view diff] exact match in snippet view article find links to article
function • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • histone acetyltransferase activity • GO:0048551 enzyme inhibitor activity • insulin-like
PADI4 (1,080 words) [view diff] exact match in snippet view article find links to article
PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation (Chromatin modifications
HIST1H2AD (519 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1-D is a protein that in humans is encoded by the HIST1H2AD gene. Histones are basic nuclear proteins that are responsible for the nucleosome
MIZF (758 words) [view diff] exact match in snippet view article find links to article
Histone H4 transcription factor is a protein that in humans is encoded by the HINFP gene. HINFP is a protein that binds to a highly conserved DNA motif
HIST1H2AL (666 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1 is a protein that in humans is encoded by the HIST1H2AL gene. Histones are basic nuclear proteins that are responsible for the nucleosome
ACSS2 (675 words) [view diff] exact match in snippet view article find links to article
linked to histone acetylation and gene regulation. In mouse neurons, Mews et al. identified a major role for the ACSS2 pathway to regulate histone acetylation
HIST1H2AG (585 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1 is a protein that in humans is encoded by the HIST1H2AG gene. Histones are basic nuclear proteins that are responsible for the nucleosome
H2BFS (688 words) [view diff] exact match in snippet view article find links to article
Histone H2B type F-S is a protein that in humans is encoded by the H2BFS gene. GRCh38: Ensembl release 89: ENSG00000234289 - Ensembl, May 2017 "Human
TAF5L (792 words) [view diff] exact match in snippet view article find links to article
gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20
RUNX1T1 (1,724 words) [view diff] exact match in snippet view article find links to article
chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript
HIST1H1T (570 words) [view diff] exact match in snippet view article find links to article
Histone H1t is a protein that in humans is encoded by the HIST1H1T gene. Histones are basic nuclear proteins responsible for nucleosome structure of the
HIST1H2AJ (551 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1-J is a protein that in humans is encoded by the HIST1H2AJ gene. Histones are basic nuclear proteins that are responsible for the nucleosome
UBE2N (1,059 words) [view diff] exact match in snippet view article find links to article
pathway • global genome nucleotide-excision repair • positive regulation of histone modification • cellular protein modification process • positive regulation
HIST1H2BI (479 words) [view diff] exact match in snippet view article find links to article
Histone H2B type 1-C/E/F/G/I is a protein that in humans is encoded by the HIST1H2BI gene. Histones are basic nuclear proteins that are responsible for
HIST1H2AB (804 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1-B/E is a protein that in humans is encoded by the HIST1H2AB gene. Histones are basic nuclear proteins that are responsible for the
Retinoblastoma-like protein 2 (1,523 words) [view diff] exact match in snippet view article find links to article
family share the ability to repress E2F activity through recruitment of a histone deacetylase". Proceedings of the National Academy of Sciences of the United
SUDS3 (435 words) [view diff] exact match in snippet view article find links to article
Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene. SDS3 is a subunit of the histone deacetylase
CUTL1 (1,833 words) [view diff] exact match in snippet view article find links to article
"Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and
Transcription initiation protein SPT3 homolog (1,037 words) [view diff] exact match in snippet view article find links to article
T, Yang XJ, Howard BH, Qin J, Nakatani Y (Jul 1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10
KDM2B (1,298 words) [view diff] exact match in snippet view article find links to article
a JmjC domain that has a histone demethylase activity demethylating trimethylated Lys-4 and dimethylated Lys-36 of histone H3. It is also the core scaffold
KRT23 (514 words) [view diff] exact match in snippet view article find links to article
2001). "Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells"
Tazemetostat (682 words) [view diff] exact match in snippet view article find links to article
of EZH2 specifically prevents the methylation of histone H3 lysine 27 (H3K27). This decrease in histone methylation alters gene expression patterns associated
ZNF451 (501 words) [view diff] exact match in snippet view article find links to article
DNA binding Cellular component • PML body • cell nucleus • nucleoplasm • histone methyltransferase complex Biological process • negative regulation of transcription
DNA (cytosine-5)-methyltransferase 3A (2,719 words) [view diff] exact match in snippet view article
4 of histone 3 (H3K4me0) for its de novo methylating activity. This protein thus seems to have an inbuilt control mechanism targeting histones only for
ING5 (448 words) [view diff] exact match in snippet view article find links to article
remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent
Alpha-thalassemia mental retardation syndrome (1,004 words) [view diff] exact match in snippet view article find links to article
alpha-globin gene cluster. Together they are all responsible for depositing the histone H3.3 at telomeric and pericentromeric regions. They are also responsible
EPC1 (635 words) [view diff] exact match in snippet view article find links to article
"Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex". J. Biol. Chem. 278 (44): 42733–6. doi:10.1074/jbc
HIST1H2AI (461 words) [view diff] exact match in snippet view article find links to article
Histone H2A type 1 is a protein that in humans is encoded by the HIST1H2AI gene. Histones are basic nuclear proteins that are responsible for the nucleosome
Long non-coding RNA (11,692 words) [view diff] exact match in snippet view article find links to article
and Tsix (see above). Epigenetic modifications, including histone and DNA methylation, histone acetylation and sumoylation, affect many aspects of chromosomal
Ru-Chih Chow Huang (1,029 words) [view diff] exact match in snippet view article find links to article
functions for nuclear histones in the early 1960s when the field lacked a consensus on types and functions of individual histone proteins. Later she made
ING3 (652 words) [view diff] exact match in snippet view article find links to article
"Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex". J. Biol. Chem. 278 (44): 42733–6. doi:10.1074/jbc
Hydroxycarboxylic acid receptor 2 (2,027 words) [view diff] exact match in snippet view article find links to article
propionate, promote Tregs through inhibiting histone deacetylase (HDAC), causing increased acetylation of histone H3 in the Foxp3 CNS1 region, and thereby
KDM4D (397 words) [view diff] exact match in snippet view article find links to article
Colaiacovo M, Shi Y (May 2006). "Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases". Cell. 125 (3): 467–81. doi:10
WHSC1 (979 words) [view diff] exact match in snippet view article find links to article
Probable histone-lysine N-methyltransferase NSD2 is an enzyme that in humans is encoded by the WHSC1 gene. This gene encodes a protein that contains four
MORF4L2 (784 words) [view diff] exact match in snippet view article find links to article
"Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex". J. Biol. Chem. 278 (44): 42733–6. doi:10.1074/jbc
MTA3 (1,756 words) [view diff] exact match in snippet view article find links to article
• chromatin binding • GO:0001948 protein binding • metal ion binding • histone deacetylase activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription
UTY (gene) (669 words) [view diff] exact match in snippet view article
Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene. This gene encodes a protein containing tetratricopeptide repeats which
CABIN1 (1,061 words) [view diff] exact match in snippet view article find links to article
MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2". Immunity. 13 (1): 85–94. doi:10
HIRIP3 (468 words) [view diff] exact match in snippet view article find links to article
shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae
TAF10 (1,485 words) [view diff] exact match in snippet view article find links to article
interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues". Nucleic Acids Res
FACT (biology) (468 words) [view diff] exact match in snippet view article
and purified human FACT binds specifically to mononucleosomes and the histone H2A/H2B dimer, but not to the H3/H4 tetramer (see: Nucleosome core particle)
KANSL3 (406 words) [view diff] exact match in snippet view article find links to article
Molecular function • histone acetyltransferase activity (H4-K5 specific) • histone acetyltransferase activity (H4-K16 specific) • histone acetyltransferase
H2AFY2 (484 words) [view diff] exact match in snippet view article find links to article
Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene. GRCh38: Ensembl release 89: ENSG00000099284 - Ensembl, May 2017 GRCm38:
ZNF217 (959 words) [view diff] exact match in snippet view article find links to article
candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes". The Journal of Biological Chemistry
Sirtuin 6 (1,468 words) [view diff] exact match in snippet view article find links to article
R, Sahay A, Toiber D (March 2017). "Neuroprotective Functions for the Histone Deacetylase SIRT6". Cell Reports. 18 (13): 3052–62. doi:10.1016/j.celrep
TADA2L (1,096 words) [view diff] exact match in snippet view article find links to article
transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms
CHD1 (782 words) [view diff] exact match in snippet view article find links to article
Boucher L, McBurney MW (August 2003). "CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins". Biochemical and Biophysical
PAXIP1 (765 words) [view diff] exact match in snippet view article find links to article
Kalkum M, Ge K (2007). "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex". J. Biol. Chem. 282 (28): 20395–406
HOXC10 (903 words) [view diff] exact match in snippet view article find links to article
cancer and transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4. Methylation of the estrogen-repressed gene HOXC10
ZNF366 (780 words) [view diff] exact match in snippet view article find links to article
and represses ER activity through the association with RIP140, CtBP and histone deacetylases. In 2010, it was shown that DC-SCRIPT can act as a coregulator
SMARCB1 (1,592 words) [view diff] exact match in snippet view article find links to article
complexes and the C-terminal region of its fusion partner SSX1 targets histones". J. Biol. Chem. 277 (7): 5498–505. doi:10.1074/jbc.M108702200. PMID 11734557
GTF3C1 (784 words) [view diff] exact match in snippet view article find links to article
multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. 19 (11): 7697–704
Ataxin 3 (1,535 words) [view diff] exact match in snippet view article find links to article
Li F, Macfarlan T, Pittman RN, Chakravarti D (Nov 2002). "Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities"
CTR9 (765 words) [view diff] exact match in snippet view article find links to article
histone monoubiquitination • JAK-STAT cascade • negative regulation of mRNA polyadenylation • regulation of transcription, DNA-templated • histone H3-K4
SRCAP (657 words) [view diff] exact match in snippet view article find links to article
(2005). "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes". J. Biol. Chem. 280 (14): 13665–70
BRDT (996 words) [view diff] exact match in snippet view article find links to article
controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. Model organisms have been used
Enzyme modulator (105 words) [view diff] exact match in snippet view article find links to article
modulators Others and non-receptor Enzymes: Cytochrome P450 modulators Histone deacetylase inhibitors Phosphodiesterase inhibitors Ion channels: Ion channel
TAF12 (1,176 words) [view diff] exact match in snippet view article find links to article
Howard T, Yang XJ, Howard BH, Qin J, Nakatani Y (1998). "Histone-like TAFs within the PCAF histone acetylase complex". Cell. 94 (1): 35–44. doi:10
LSM10 (599 words) [view diff] exact match in snippet view article find links to article
protein facilitates 3'-end formation by stabilizing U7 snRNP binding to histone pre-mRNA". Molecular and Cellular Biology. 19 (5): 3561–70. doi:10.1128/mcb
H2BFWT (349 words) [view diff] exact match in snippet view article find links to article
H2B histone family, member W, testis-specific is a protein that in humans is encoded by the H2BFWT gene. Histones are basic nuclear proteins that are
Autoimmune regulator (3,079 words) [view diff] exact match in snippet view article find links to article
read chromatin marks through the degree of methylation at the tail of histone H3. More specifically, PHD1 is able to recognize unmethylation at the H3
VRK1 (851 words) [view diff] exact match in snippet view article find links to article
therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor
Cutaneous T cell lymphoma (887 words) [view diff] exact match in snippet view article find links to article
Vorinostat (Zolinza) a hydroxymate histone deacetylase (HDAC) inhibitor (2009) Romidepsin (Istodax) a cyclic peptide histone deacetylase (HDAC) inhibitor (2018)