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searching for nPM1 9 found (41 total)

alternate case: NPM1

Enzomenib (156 words) [view diff] exact match in snippet view article find links to article

proteins. Enzomenib particularly in patients with KMT2A (MLL) rearrangements or NPM1 mutations. The U.S. Food and Drug Administration (FDA) has granted both Fast

NEK2 (1,182 words) [view diff] exact match in snippet view article find links to article

Phosphorylates: PPP1CC; SGOL1; NECAB3 and NPM1. Essential for localization of MAD2L1 to kinetochore and MAPK1 and NPM1 to the centrosome. Isoform 1 phosphorylates

Tumors of the hematopoietic and lymphoid tissues (2,329 words) [view diff] exact match in snippet view article find links to article

with t(1;22)(p13.3;q13.1); RBM15-MKL1 AML with BCR-ABL1 AML with mutated NPM1 AML with biallelic mutation of CEBPA AML with mutated RUNX1 AML with myelodysplasia-related

Blastic plasmacytoid dendritic cell neoplasm (2,648 words) [view diff] exact match in snippet view article find links to article

32–67% of all BPDCN cases and often accompanied by mutations in either the NPM1 or SRSF2 gene. Numerous other genetic abnormalities are associated with the

HSPA1B (1,999 words) [view diff] exact match in snippet view article find links to article

Liu D, Qian D, Dai J, An Y, Jiang S, et al. (June 2012). "Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and

Gene signature (2,164 words) [view diff] exact match in snippet view article find links to article

Delwel R, Löwenberg B, Valk PJ (December 2005). "Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities

Minimal residual disease (3,533 words) [view diff] exact match in snippet view article find links to article

t(15;17) PML-RARA, t(8;21) AML1-RUNX1T1 (AML-ETO), inv(16), BCL2, FLT3, IDH1/2, NPM1. Uses: Chromosomal translocation MRD detection widely used as a standard

Revumenib (607 words) [view diff] exact match in snippet view article find links to article

in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)" at ClinicalTrials.gov Clinical trial number NCT05918913

MicroRNA sequencing (5,200 words) [view diff] exact match in snippet view article find links to article

miR-127, miR-299-5p, miR-323 with t(8;21) or inv(16) let-7b/c, miR-127 with NPM1 mutations miR-10a/b, let-7, miR-29, miR-204, miR-128a, miR-196a/b with FLT3