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searching for NPM1 8 found (40 total)

alternate case: nPM1

NEK2 (1,182 words) [view diff] exact match in snippet view article find links to article

Phosphorylates: PPP1CC; SGOL1; NECAB3 and NPM1. Essential for localization of MAD2L1 to kinetochore and MAPK1 and NPM1 to the centrosome. Isoform 1 phosphorylates

Tumors of the hematopoietic and lymphoid tissues (2,329 words) [view diff] exact match in snippet view article find links to article

with t(1;22)(p13.3;q13.1); RBM15-MKL1 AML with BCR-ABL1 AML with mutated NPM1 AML with biallelic mutation of CEBPA AML with mutated RUNX1 AML with myelodysplasia-related

Blastic plasmacytoid dendritic cell neoplasm (2,648 words) [view diff] exact match in snippet view article find links to article

32–67% of all BPDCN cases and often accompanied by mutations in either the NPM1 or SRSF2 gene. Numerous other genetic abnormalities are associated with the

HSPA1B (1,999 words) [view diff] exact match in snippet view article find links to article

Liu D, Qian D, Dai J, An Y, Jiang S, et al. (June 2012). "Nucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and

Gene signature (2,164 words) [view diff] exact match in snippet view article find links to article

Delwel R, Löwenberg B, Valk PJ (December 2005). "Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities

Minimal residual disease (3,533 words) [view diff] exact match in snippet view article find links to article

t(15;17) PML-RARA, t(8;21) AML1-RUNX1T1 (AML-ETO), inv(16), BCL2, FLT3, IDH1/2, NPM1. Uses: Chromosomal translocation MRD detection widely used as a standard

Revumenib (542 words) [view diff] exact match in snippet view article find links to article

R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation (AUGMENT-101)" at ClinicalTrials.gov Clinical trial number NCT05918913

MicroRNA sequencing (5,200 words) [view diff] exact match in snippet view article find links to article

miR-127, miR-299-5p, miR-323 with t(8;21) or inv(16) let-7b/c, miR-127 with NPM1 mutations miR-10a/b, let-7, miR-29, miR-204, miR-128a, miR-196a/b with FLT3