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searching for Synaptic pruning 21 found (54 total)

Glutamate hypothesis of schizophrenia (3,899 words) [view diff] exact match in snippet view article find links to article

receptors, downregulation of this inhibitory receptor may increase global synaptic pruning activity. While difference in expression or distribution is observed[citation

Anna Huttenlocher (1,072 words) [view diff] exact match in snippet view article find links to article

"From Loss to Memory: Behind the Discovery of Synaptic Pruning". It describes the discovery of synaptic pruning and its current relevance to early learning

Critical period (8,680 words) [view diff] exact match in snippet view article find links to article

neurons competing for connections). Microglia inherently play a role in synaptic pruning during adolescence. As resident immune cells of the central nervous

Body memory (3,575 words) [view diff] exact match in snippet view article find links to article

testosterone levels during puberty influence neural development, affecting synaptic pruning and myelination in the prefrontal cortex. These changes have long-term

Excitatory synapse (2,547 words) [view diff] exact match in snippet view article find links to article

plaques and neurofibrillary tangles, as well as neuronal cell death and synaptic pruning. The principle drug treatments on the market deal with antagonizing

Why We Sleep (2,415 words) [view diff] exact match in snippet view article find links to article

non-rapid eye movement sleep (NREM), and the impact sleep has on "synaptic pruning" and the creation of memories during a human's lifespan are also covered

CX3C motif chemokine receptor 1 (3,133 words) [view diff] exact match in snippet view article find links to article

Pagani F, Maggi L, Scianni M, Panzanelli P, et al. (September 2011). "Synaptic pruning by microglia is necessary for normal brain development". Science. 333

Anhedonia (5,317 words) [view diff] exact match in snippet view article find links to article

combination of the occurrence of critical neuronal development and synaptic pruning of brain regions important for social behavior and environmental changes

Maturity (psychological) (3,876 words) [view diff] exact match in snippet view article

20s. Accompanying the growth of the prefrontal cortex is continued synaptic pruning (the trimming of rarely used synapses) as well as increased myelination

Benzodiazepine (17,215 words) [view diff] exact match in snippet view article find links to article

anti-anxiety activity. GABAA receptors participate in the regulation of synaptic pruning by prompting microglial spine engulfment. Benzodiazepines have been

Miriam Merad (2,046 words) [view diff] exact match in snippet view article find links to article

contribution of tissue resident macrophages to organ physiology including synaptic pruning, gut peristaltism, fat metabolism and vascular integrity. The Merad

Ben Barres (3,409 words) [view diff] exact match in snippet view article find links to article

Stevens, Beth (2012). "The complement system: an unexpected role in synaptic pruning during development and disease". Annual Review of Neuroscience. 35

NBPF1 (2,276 words) [view diff] exact match in snippet view article find links to article

severity, which often results from an excess of neurons that do not under synaptic pruning. The NBPF1 protein is also found to be disrupted by a chromosomal translocation

Dendritic spine (5,689 words) [view diff] exact match in snippet view article find links to article

MR, Li M, Shen H, Smith SS (October 2021). "Preventing adolescent synaptic pruning in mouse prelimbic cortex via local knockdown of α4βδ GABAA receptors

Microglia (5,772 words) [view diff] exact match in snippet view article find links to article

has also been shown that microglia are involved in the process of synaptic pruning during brain development. Post-inflammation, microglia undergo several

Psychological trauma (8,342 words) [view diff] exact match in snippet view article find links to article

neurophysiological changes like slowed myelination, abnormalities in synaptic pruning, shrinking of the hippocampus, cognitive and affective impairment.

Genetics of synesthesia (2,911 words) [view diff] exact match in snippet view article find links to article

individuals, these connections are eliminated through a process known as synaptic pruning, which refines and specializes neural circuits during early development

Rudolph E. Tanzi (4,371 words) [view diff] exact match in snippet view article find links to article

neuronal Aβ deposition/tangle formation induces microglial activation and synaptic pruning/axotomy beginning with the astrocytic release of MCP1. 2018: Showed

MTOR (12,682 words) [view diff] exact match in snippet view article find links to article

2014). "Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits". Neuron. 83 (5): 1131–43. doi:10.1016/j.neuron.2014.07.040

Risk factors of schizophrenia (14,934 words) [view diff] exact match in snippet view article find links to article

the C4A gene in schizophrenia risk. C4A was found to play a role in synaptic pruning, and increased C4A expression leads to reduced dendritic spines and

Biology of bipolar disorder (11,130 words) [view diff] exact match in snippet view article find links to article

reflect abnormal development of amygdala, possibly involving impaired synaptic pruning, although this may reflect medication or compensatory effects; that