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Longer titles found: Telomerase reverse transcriptase (view)

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alternate case: reverse transcriptase

Atevirdine (267 words) [view diff] exact match in snippet view article find links to article

Atevirdine is a non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV. Preparation of the pyridylpiperazine moiety

Delavirdine (DLV) (brand name Rescriptor) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare. It is used as part

virus infection. It is a cytidine nucleoside analog and nucleoside reverse transcriptase inhibitor. that inhibits HIV-1 replication in vitro. During phase

ATC code J05 Antivirals for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric

the treatment of HIV infection. It is classified as a nucleoside reverse transcriptase translocation inhibitor (NRTTI). Merck is developing a subdermal

Fosdevirine is an experimental antiviral agent of the non-nucleoside reverse transcriptase inhibitor class that was studied for potential use in the treatment

research for the treatment of HIV/AIDS. It acts as a nucleoside reverse transcriptase inhibitor (NRTI). The drug was discovered by Raymond F. Schinazi

experimental agent for the treatment of HIV. It is a non-nucleoside reverse transcriptase inhibitor. While emivirine showed promising antiviral activity in

Racivir is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Pharmasset for the treatment of HIV. It is the enantiomer of

treatment of HIV/AIDS. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced

"Efficacy, safety, bone and metabolic effects of HIV nucleoside reverse transcriptase inhibitor BMS-986001 (AI467003): a phase 2b randomised, controlled

SPD754, sometimes abbreviated to ATC) is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV. It is structurally related to lamivudine

Doravirine, sold under the brand name Pifeltro, is a non-nucleoside reverse transcriptase inhibitor medication developed by Merck & Co. for use in the treatment

Lodenosine is a failed experimental agent for the treatment of HIV. Its development was discontinued on January 11, 2001. "Drug Profile: Lodenosine". AdisInsight

HIV. It is taken by mouth. Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor and is a prodrug of tenofovir. It was developed by Gilead

Clevudine (INN) is an antiviral drug for the treatment of hepatitis B (HBV). It is already approved for HBV in South Korea and the Philippines. It is marketed

Capravirine was a non-nucleoside reverse transcriptase inhibitor which reached phase II trials before development was discontinued by Pfizer. Both phase

and when the virus has not developed resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) and integrase strand transfer inhibitors.

HIV-1 nucleoside analog reverse transcriptase inhibitor; and tenofovir alafenamide, an HIV-1 nucleoside analog reverse transcriptase inhibitor. It was approved

antiretroviral medication for the treatment of HIV/AIDS. It contains three reverse transcriptase inhibitors patented by GlaxoSmithKline and marketed by a joint venture

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications

Dapivirine is a non-nucleoside reverse transcriptase inhibitor developed at Janssen Therapeutics (formerly Tibotec Therapeutics). The International Partnership

appears to be okay. Lamivudine and abacavir are both nucleoside reverse transcriptase inhibitors (NRTI). Abacavir/lamivudine was approved for medical

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) of HIV-1

1500) is drug used to treat HIV infection. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Elsulfavirine is a prodrug which is metabolized

inhibitor (INSTI), and 300 mg lamivudine, a nucleoside analogue reverse transcriptase inhibitor (NRTI). It is taken by mouth. It was approved for use

genome. These tags can be appended to gene specific primers for reverse transcriptase polymerase chain reaction (RT-PCR) experiments, circumventing genomic

nucleoside reverse transcriptase inhibitor Nevirapine non-nucleoside reverse transcriptase inhibitor Stavudine nucleoside reverse transcriptase inhibitor

Microbiology at McGill University. His laboratory primarily studies HIV reverse transcriptase, the molecular basis for drug resistance, and gene therapy. He received

biological activity of novel human immunodeficiency virus (HIV) reverse transcriptase inhibitors. Other software tools which help to model pharmacophores

end of the mRNA. The primer is allowed to anneal to the RNA and reverse transcriptase is used to synthesize cDNA from the RNA until it reaches the 5'

the help of a specific enzyme called reverse transcriptase. A retrotransposon that carries reverse transcriptase in its sequence can trigger its own transposition

Jewish Americans, see Lists of Jewish Americans. David Baltimore, reverse transcriptase, Nobel Prize (1975) Baruj Benacerraf, immunologist, Nobel Prize

polymerases with improved activity. The binary structure of a TNA reverse transcriptase has also been solved by X-ray crystallography, revealing the importance

nucleoside reverse transcriptase inhibitor Nevirapine non-nucleoside reverse transcriptase inhibitor Zidovudine nucleoside reverse transcriptase inhibitor

and meiotic-specific antisense transcript complementary to the reverse transcriptase (RT) and ribonuclease A (RNaseA) genes of the proviral retrotransposon

The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children or EMLc), published by the World Health Organization

predicted rho-independent transcription terminators, and microarray and reverse-transcriptase PCR experiments indicate that the S. coelicolor version is transcribed

applications include the discovery of new Myeloperoxidase ligands, HIV reverse transcriptase inhibitors, applications in anti-viral bio-activity profiling, the

cause these adverse drug reactions than others. Non-nucleoside reverse transcriptase inhibitors have been shown to have the highest rate of causing immune-related

Non-nucleoside reverse transcriptase inhibitor Lamivudine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleoside reverse transcriptase inhibitor

(LTR) retrotransposons, also referred to as metazoan-infecting reverse transcriptase viruses. The genomic arrangement of members of the Belpaoviridae

inhibitor (Ki = 2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. It was patented in

analog reverse-transcriptase inhibitor Rilpivirine Non-nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleotide analog reverse-transcriptase

Then, the RNA is reverse transcribed to viral DNA using the host reverse transcriptase in the cytoplasm. The viral product is made and assembled in the

Year approved Abacavir HIV ViiV Healthcare Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox

epsilonretrovirus genus based on similarities of the gene coding for the reverse transcriptase conserved in retroviruses. The virus infects soft tissues of the

reverse transcriptase inhibitors (NNRTI) inhibit reverse transcriptase by binding to an allosteric site on it. Cessation of a non-nucleoside reverse transcriptase

Institute would lead to the discovery of the first non-nucleoside reverse transcriptase inhibitor (NNRTI). It was also Janssen who would introduce him to

failure and no known or suspected resistance to any non-nucleoside reverse transcriptase inhibitor or integrase inhibitor. "Dolutegravir / rilpivirine (Juluca)

is most widely cited for his involvement in creating a real-time reverse transcriptase PCR (RRT-PCR) assay based on the avian influenza virus matrix gene

variety of these concepts while in the lab, such as Group ll Intron reverse transcriptase mechanisms or RNA sequencing. One of the first concepts surrounding

containing nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitor (PI), and non-nucleoside reverse transcriptase inhibitors (NNRTI).

Spain and Switzerland. The company markets 17 products: Nucleoside reverse transcriptase inhibitors (NRTIs): abacavir (brand name Ziagen) lamivudine (brand

template. This reaction takes place at 25 °C. In the second step, reverse transcriptase synthesis extends the DNA oligonucleotides that have annealed to

K. (2 August 2017). "Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations

reverse transcriptase inhibitors, rilpivirine and etravirine and was first to characterize the metabolism of the nonnucleoside reverse transcriptase inhibitor

inhibitor Lamivudine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleoside reverse transcriptase inhibitor Clinical data Other names

inhibitor Lamivudine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleoside reverse transcriptase inhibitor Clinical data Other names

Martin Temin (1934–1994), geneticist and virologist who discovered reverse transcriptase, Nobel Prize in Physiology or Medicine (1975) Ronald Vale (born

Ainuovirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Kainos Medicine for the treatment of HIV infections. Ainuovirine

Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction". Drug Metabolism and Disposition. 37

Different types of reverse transcriptase polymerases are available to suit different needs and reaction conditions. Reverse transcriptase enzymes commonly

(CP, P03542) ORF V – P5: pro-pol (P03554): protease, bifunctional reverse transcriptase and RNaseH ORF VI – P6: transactivator/viroplasmin (P03559): inclusion

Patrick Dunn, Steven Swallow, Zachary Kevin Sweeney, "Nonnucleoside reverse transcriptase inhibitors", issued 2008-08-02  "Drug Profile: Lasinavir". AdisInsight

containing trifluoromethyl groups include efavirenz (Sustiva), an HIV reverse transcriptase inhibitor; fluoxetine (Prozac), an antidepressant; and celecoxib

polymerase from the A-family polymerases, and HIV reverse transcriptase from the reverse transcriptase family have been developed to facilitate the synthesis

contains numerous flavonoid compounds that have anti-microbial, anti-reverse transcriptase, and anti-inflammatory effects. Hutchinson, J. & Rendle, A. B. Flora

anti-viral drugs used to treat HIV, specifically nucleoside analog reverse transcriptase inhibitors (NRTIs), interfere with an enzyme needed in the production

3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proceedings of the National Academy of Sciences of the United States

validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with

development of lipodystrophy is associated with specific nucleoside reverse transcriptase inhibitors (NRTI). Mitochondrial toxicity is postulated to be involved

Evaluation of the Efficacy of Once-Daily PI & Once-Daily Non-Nucleoside Reverse Transcriptase Inhibitor - Containing Therapy Combinations for Initial Treatment

During her Ph.D, Rittinger studied human immunodeficiency virus reverse transcriptase. At MRC National Institute for Medical Research Rittinger studied

Cytochrome P450 inhibitor Emtricitabine Reverse-transcriptase inhibitor Tenofovir disoproxil Reverse-transcriptase inhibitor Clinical data Trade names Stribild

Lamivudine/raltegravir Combination of Lamivudine Reverse-transcriptase inhibitor Raltegravir Integrase inhibitor Clinical data Trade names Dutrebis Routes

hepatitis from agents with mitochondrial toxicity, including nucleoside reverse transcriptase inhibitors used to treat HIV, and a rare condition known as Jamaican

(simulation) Reproductive tract infection Respiratory tract infection Reverse-transcriptase inhibitor, a class of antiretroviral drug Ramp travel index, a measure

H.; Kim, N. G.; Huh, H.; Kim, J. (2004). "Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava"

and 3' end sequences. Many of these IEPs, including LtrA, share a reverse transcriptase domain and a "Domain X". Maturase K (MatK) is a protein somewhat

contains numerous flavonoid compounds that have anti-microbial, anti-reverse transcriptase, and anti-inflammatory effects. In the past many species were described

in PAR-CLIP, or other types of errors that can be introduced by reverse transcriptase when it reads through the crosslink site in standard HITS-CLIP method

gynecologic malignancies and malignant effusions detected by nested reverse transcriptase-polymerase chain reaction". Laboratory Investigation. 82 (9): 1147–53

biological properties including: anti-tumor, antiviral activity (reverse transcriptase inhibitory activity), neuroprotection, cardioprotection, anti-inflammation

inhibitors: indinavir, ritonavir, saquinavir, nelfinavir; non-nucleoside reverse-transcriptase inhibitors (antiretroviral drugs): nevirapine delavirdine, efavirenz

system, referred to as DLV Delavirdine (DLV), a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare DNSSEC Lookaside Validation

of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". J. Biol. Chem

TG; Kim, SH; Kim, NG; Huh, H; Kim, J (2004). "Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava"

capture–enzyme-linked immunosorbent assay (MAC-ELISA) and viral RNA detection by reverse transcriptase (RT-PCR) can also be used to diagnose dengue fever. Dengue virus

inhibitor Etravirine (TMC125, tradename Intelence), a non-nucleoside reverse transcriptase inhibitor (NNRTI) Bedaquiline (TMC207/R207910, tradename Sirturo)

Genvoya, Odefsey and GS 9883, as well as Merck's non-nucleoside reverse transcriptase inhibitor MK-1439 (Doravirine). Current studies include a study

PMRT may refer to: Peak muscle resistance testing Paired multiplex reverse transcriptase PCR (PMRT-PCR) Pere Marquette Rail-Trail Progressive muscle relaxation

multiple human cytochrome P450 mRNA molecules using competitive reverse transcriptase-PCR". DNA Cell Biol. 17 (3): 231–8. doi:10.1089/dna.1998.17.231

C22H26O5 may refer to: Calanolide A, an experimental non-nucleoside reverse transcriptase inhibitor Hydroxyestrone diacetate, a synthetic, steroidal estrogen

of Emtricitabine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleotide analogue reverse transcriptase inhibitor Clinical data Trade

Vesanoid 1996 – Released anti-viral chemotherapeutic agent Hivid (HIV reverse transcriptase inhibitor) 1997 – Released HIV protease inhibitor Invirase 1999

as "Crix belly", after indinavir (Crixivan). The Proteolysis Map Reverse-transcriptase inhibitor Discovery and development of NS5A inhibitors Discovery

Fipravirimat§ Protease Inhibitors (PI) (Discovery and development) Reverse-transcriptase inhibitors (RTIs) Combined formulations Abacavir/lamivudine#

1432-1033.2003.03555.x Lorsch JR; Bartel DP; Szostak JW (1995). "Reverse transcriptase reads through a 2′–5′ linkage and a 2′-thiophosphate in a template"

1432-1033.2003.03555.x Lorsch JR; Bartel DP; Szostak JW (1995). "Reverse transcriptase reads through a 2′–5′ linkage and a 2′-thiophosphate in a template"

therapy (ART), nucleoside reverse transcriptase inhibitors (NRTIs), protease inhibitors (PI), and non-nucleoside reverse transcriptase inhibitors (NNRTIs) with

A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase". AIDS. 11 (4): 534–6. PMID 9084803. Li L, Lu X, Peterson CA, Legerski

in vitro activation by Hsc70 and Hsp40 of duck hepatitis B virus reverse transcriptase, an assumed Hsp90 client protein". The Journal of Biological Chemistry

variability already present in HIV-1 (owing to its mutation-happy reverse transcriptase). Vif therefore acts via APOBEC3G to increase the likelihood of

as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase". Nucleic Acids Res. 8 (13): 2885–94. doi:10.1093/nar/8.13.2885

Sequencing for Genotyping of Human Immunodeficiency Virus Type 1 Reverse Transcriptase". J Clin Microbiol. 38 (7): 2715–2721. doi:10.1128/JCM.38.7.2715-2721

polyprotein, an Rnase H (RH) which splits the DNR-RNA hybrid, a reverse transcriptase (RT) which produces a cDNA copy of the transposons RNA and a DDE

So AG, Scott WA (May 2007). "Stable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding

"Genomic and genetic analysis of Bordetella bacteriophages encoding reverse transcriptase-mediated tropism-switching cassettes". Journal of Bacteriology.

(2018). "A computational study for rational HIV-1 non-nucleoside reverse transcriptase inhibitor selection and the discovery of novel allosteric pockets

Hamosh A., Greider C. W. (2005). "Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita"

5"-AAGCAGTGGTATCAACGCAGAGTACrGrG+G-3’) and Superscript II reverse transcriptase. Superscript II reverse transcriptase has additional terminal transferase activity

of detection of circulating colorectal cancer cells using CGM2 reverse transcriptase-polymerase chain reaction assay". Surgery. 139 (4): 556–62. doi:10

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75

Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor) Tipranavir (HIV

Management RTP – (i) Real-time Transport Protocol RT-PCR – (i) reverse transcriptase polymerase chain reaction (sometimes real-time polymerase chain

inhibits viral development by interfering with DNA-polymerase and reverse transcriptase activity. In cyanobacteria and plants, SQDG is synthesized in two

receptor antagonists Non-nucleoside reverse transcriptase inhibitors Nucleoside and nucleotide reverse transcriptase inhibitors PDE5 inhibitors Proton pump

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75

analogues and other older HIV drug treatments such as the nucleoside reverse transcriptase inhibitors [NRTIs] like zidovudine (AZT) and stavudine (d4T). Other

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75

Lewi P, Vanham G, Janssen P., In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus

Matsuzuka F, et al. (2007). "Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Arch. 440 (5): 461–75

of nucleic acid-based techniques such as in-situ hybridization, reverse-transcriptase polymerase chain reaction, and nucleic acid microarrays for specialized

"Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance". Science. 282 (5394): 1669–75

nucleoside reverse transcriptase inhibitors (NRTIs), nucleotide reverse transcriptase inhibitors (NtRTIs), Non-nucleoside reverse transcriptase inhibitors

vertical transmission AIDS HAART, such as protease inhibitors and reverse-transcriptase inhibitors zidovudine (perinatally) blood product screening safe

inosine to form N1-cyanoethylinosine (ce1I). This serves to stall reverse transcriptase and lead to truncated cDNA molecules. This was combined with deep-sequencing

genome using virus-specific probes. Variations of PCR such as nested reverse transcriptase PCR and real time PCR can also be used to determine viral loads

"Detection of human 11 beta-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform

SanFilippo, J., Singh, R. N., Matsuura, M., & Lambowitz, A. M. (1999). A reverse transcriptase/maturase promotes splicing by binding at its own coding segment

Diaryltriazines and Diarylpyrimidines Are Highly Potent Nonnucleoside Reverse Transcriptase Inhibitors with Possible Applications as Microbicides, Antimicrob

antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid

Berkhout B, Jebbink M, Zsíros J (1999). "Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus". J. Virol

inhibits other important biological targets including the virus’ reverse transcriptase and the inhibition of cyclooxygenase and 5′-lipoxygenase. Avarol’s

Kollman PA (April 2005). "Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and

anti-inflammatory drugs increase the antiretroviral activity of nucleoside reverse transcriptase inhibitors in HIV type-1-infected T-lymphocytes: role of multidrug

et al. (2003). "Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation

with a DNA intermediate. Typically, the virus will use its own reverse transcriptase enzyme to create DNA from the RNA genome. The FeFV viral genome

development of non-nucleoside reverse-transcriptase inhibitors Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors Broadly neutralizing

specific primer (GSP). The primer binds to the mRNA, and the enzyme reverse transcriptase adds base pairs to the 3' end of the primer to generate a specific

University. The patent claims to cover Stavudine, a nucleoside analog reverse-transcriptase (NARTI) active against HIV. This was the first acquisition ever

A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase". AIDS. 11 (4): 534–6. PMID 9084803. Bochkareva E, Frappier L, Edwards

determinants in the interaction between the RNA encapsidation signal and reverse transcriptase of avian hepatitis B viruses". Journal of Virology. 71 (7): 4971–4980

is typically a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus two nucleoside analog reverse transcriptase inhibitors (NRTIs) Under research

Schematic: A tagged random hexamer primer is used to prime M-MuLV reverse transcriptase to generate aminoallyl dUTP- modified cDNA fragments in fixed cells

is typically a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus two nucleoside analog reverse transcriptase inhibitors (NRTIs) Under research

blood or tissue. According to Zeaiter et. al., “species-specific reverse-transcriptase polymerase chain reaction (RT PCR) was compared to serology” and

include Mediator Complex Subunit 12 (MED12) exon 2, Telomerase Reverse Transcriptase (TERT) promoter, and Retinoic Acid Receptor Alpha (RARA); important

Oricchio, Elisa; Grillo, Caterina; et al. (20 May 2008). "Endogenous reverse transcriptase as a mediator of ursolic acid's anti-proliferative and differentiating

About 300 samples were seeded from 34 protein types including HIV Reverse Transcriptase Complex (an enzyme that is a chemical key to the replication of

millitre sooner than those taking similarly potent non-nucleoside reverse transcriptase inhibitors or protease inhibitors. This statistically significant

Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction". Drug Metabolism and Disposition. 37

such clusters, such as ‘‘EST, weakly similar to ORF2 contains a reverse transcriptase domain [H. sapiens],’’ are derived from the title of a characterized

through the G-less cassette. Park, JH; Magan, N (2014-11-12). "Reverse Transcriptase-Coupled Quantitative Real Time PCR Analysis of Cell-Free Transcription

ADP-ribosylation DNA repair negative regulation of telomerase RNA reverse transcriptase activity protein poly-ADP-ribosylation DNA ADP-ribosylation negative

Kerry; Sunpath, Henry (2006). "A high incidence of nucleoside reverse transcriptase inhibitor (NRTI)-induced lactic acidosis in HIV-infected patients

Higashibata H, Fujiwara S (March 2012). "Mutations to create thermostable reverse transcriptase with bacterial family A DNA polymerase from Thermotoga petrophila

X (2008). "Dynamic binding orientations direct activity of HIV reverse transcriptase". Nature. 453 (7192): 184–189. Bibcode:2008Natur.453..184A. doi:10

MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors". Drug Metab. Dispos. 35 (3): 340–4. doi:10.1124/dmd

"Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase". Virus Research. 134 (1–2): 124–46. doi:10.1016/j.virusres.2007

mechanisms of a number of available anti-HIV drugs prevent either viral reverse transcriptase enzyme or protease enzyme, allowing the virus to enter the cell

There are various tests: Antigen determination Virus isolation Reverse transcriptase PCR as well as real-time RT-PCR Antibody determination through virus

polyoxometalate-mediated inactivation of DNA polymerases: an analysis with HIV-1 reverse transcriptase indicates specificity for the DNA-binding cleft". Biochemical Journal

Ikeguchi M, Hirooka Y, Kaibara N (September 2003). "Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled

throughout the genome. The LINEs contain a sequence that encodes a reverse transcriptase protein. This protein aids in copying the RNA transcripts of LINEs

development of non-nucleoside reverse transcriptase inhibitors Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors Lederman

Fogli, L. K.; Algra, S.; Breault, D. T. (2010). "Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells".

"Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is

A-type particles and C-type particles. Also, low expression of reverse transcriptase was observed. However the majority of ERS are defective (stop codons

Farrar CT, Frontera W, et al. (June 2007). "Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function

of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". The Journal of

Blobel G, Cerami A, Bukrinsky M (Oct 1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

polymerase to replicate its RNA genome, but they discovered an enzyme, reverse transcriptase (in a mouse leukemia retrovirus), that converts RNA to DNA (involved

polymerase to replicate its RNA genome, but they discovered an enzyme, reverse transcriptase (in a mouse leukemia retrovirus), that converts RNA to DNA (involved

Popov S, Dubrovsky L, Lee MA, et al. (1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

KD; Loeb, LA (1997). "Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate". Mutation

2 (ORF 2) codes a protein which possesses both endonuclease and reverse transcriptase activities. This enables the LINE mRNA to be reverse-transcribed

Nobel Prize in Physiology & Medicine in 1975 for the discovery of reverse transcriptase. Has served as president of both the Rockefeller University and

lab as an expert to study structure-function relationships of HIV reverse transcriptase. Becerra joined the National Eye Institute (NEI) as a visiting scientist

Stephen J.; Alter, Blanche P. (2006-09-01). "Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure"

Vivo and in Vitro and Represses Telomerase Activity and Telomerase Reverse Transcriptase mRNA Expression in the Cells". Biological & Pharmaceutical Bulletin

nucleic acid synthesis inhibitors MeSH D27.505.519.389.675.850 – reverse-transcriptase inhibitors MeSH D27.505.519.389.735 – phosphodiesterase inhibitors

biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors". Bioorg. Med. Chem. Lett. 16 (8): 2109–12. doi:10.1016/j

regulation of telomere capping positive regulation of telomerase RNA reverse transcriptase activity regulation of telomere maintenance RNA metabolic process

shown that highly active antiretroviral therapy-regimens including reverse transcriptase and potent protease inhibitors-are capable of suppressing HIV viral

Propofol Epinephrine Propylene glycol (D-lactic acidosis) Nucleoside reverse-transcriptase inhibitors Abacavir/dolutegravir/lamivudine Emtricitabine/tenofovir

S, Marcellin P, Lidereau R, Beaune P, de Waziers I (Sep 2007). "Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and

Sande Merle A (July 2002). "Emerging resistance to nonnucleoside reverse transcriptase inhibitors: a warning and a challenge". JAMA. 288 (2): 239–41. doi:10

infection with Hepatitis and HIV. Examples of direct nucleoside analog reverse-transcriptase inhibitors (NRTIs) include Tenofovir disoproxil, Tenofovir alafenamide

refinement of CRISPR-Cas9 is called Prime Editing. This method links a reverse transcriptase to an RNA-guided engineered nuclease that only makes single-strand

3). EhLINE1 encodes an endonuclease (EN) protein (in addition to reverse transcriptase and nucleotide-binding ORF1), which has similarity with bacterial

2005 Converging Pattern, December 8 – 17, 2006 Fraser Taylor: Reverse Transcriptase, November 13 –February 13, 2006 Interstellar Low Ways, October 15

Viña, J.; Serrano, M.; Blasco, MA (November 2008). "Telomerase reverse transcriptase delays aging in cancer resistant mice". Cell. 135 (4): 609–622.

A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase". AIDS. 11 (4): 534–6. PMID 9084803. Niu H, Erdjument-Bromage H

inhibit HIV-1 infection through inhibition of HIV-1 protease & reverse transcriptase activity". Indian J Med Res. 137 (3): 540–548. PMC 3705663. PMID 23640562

capillary dysplasia (mutations in FoxF1) Mutations in telomerase reverse transcriptase (TERT) Mutations in telomerase RNA component (TERC) Mutations in

ISSN 0028-0836. PMID 1840648. S2CID 2713293. Lingner, J. (1997-04-25). "Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase". Science. 276 (5312):

Popov S, Dubrovsky L, Lee MA, et al. (1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

include protease inhibitors used to treat HIV/AIDS and Hepatitis C, reverse-transcriptase inhibitors targeting HIV/AIDS, neuraminidase inhibitors targeting

and when the virus has not developed resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) and integrase strand transfer inhibitors. The

Apricitabine, a drug candidate containing a 1,3-oxathiane, is a nucleoside reverse transcriptase inhibitor.

significantly reduced titres in the thorax. The genome is detectable by reverse transcriptase-polymerase chain reaction in the head, thorax, abdomen and wings

Modiano, JF; Bagchi, A (2014). "Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan

the table below. In a technical comparison between quantitative reverse transcriptase PCR and digital PCR, the expression of the rat gabrd gene was examined

Farnesyltransferase 2.6 GABA transaminase 2.7 Nucleotidyltransferase Integrase Reverse transcriptase Protein kinase Tyrosine kinase Janus kinase Hydrolase (EC 3) 3.1

affect CYP3A or p-gp. When taking daclatasvir with non-nucleoside reverse transcriptase inhibitors, the dose of daclatasvir is increased to overcome CYP3A

PMID 10329640. Idriss H, Kawa S, Damuni Z, et al. (2000). "HIV-1 reverse transcriptase is phosphorylated in vitro and in a cellular system". Int. J. Biochem

extracts have a mild effect on HIV-1 and HIV-2 strains, and HIV-1 reverse transcriptase. Clausamine E is cytotoxic to the human leukemia cell line HL60

virus has been cloned and cDNA probes are available for diagnosis. Reverse transcriptase polymerase chain reaction (RT-PCR) methods have been developed for

protein-coding region, or open reading frame (ORF). Both gag and pol proteins are required for reverse transcriptase, which is essential to HIV1 replication.

Ihjima K, Yamada O (May 2005). "IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol

"Development and Evaluation of Serotype- and Group-Specific Fluorogenic Reverse Transcriptase PCR (Taq Man) Assays for Dengue Virus" (PDF). Journal of Clinical

via telomere lengthening positive regulation of telomerase RNA reverse transcriptase activity mRNA export from nucleus RNA metabolic process interleukin-12-mediated

Popov S, Dubrovsky L, Lee MA, et al. (1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

cases of ependymoma recurrences. ERBB2, ERBB4, and human telomerase reverse transcriptase (TERT) gene expression promote tumor cell proliferation, contributing

Swaminathan S (January 2010). "Dose adjustment of the non-nucleoside reverse transcriptase inhibitors during concurrent rifampicin-containing tuberculosis

histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells". J. Biol. Chem.

histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells". The Journal of

antiretroviral therapy despite extensive resistance within HIV-1 reverse transcriptase after the first virologic failure". BMC Infectious Diseases. 18

involved an intron invasion. Two definitive mechanisms of intron loss, reverse transcriptase-mediated intron loss (RTMIL) and genomic deletions, have been identified

with a focus on HIV. He has shown that adherence to non-nucleoside reverse-transcriptase inhibitor HIV therapy has a linear dose-response pattern. He was

protein while ORF2 encodes a protein containing endonuclease (EN) and reverse transcriptase (RT) activity, which nick a site in DNA, then produce a copy via

DNA for cloning experiments may also be obtained from RNA using reverse transcriptase (complementary DNA or cDNA cloning), or in the form of synthetic

Vladimir Ilyich Lenin" (1970) USSR State Prize for the cycle of works "Reverse transcriptase (revertase)" (1979) Jubilee badge "225 years of MSU" (1980) Medal

Hüllermeier, E; Heider, D (2016). "Exploiting HIV-1 protease and reverse transcriptase cross-resistance information for improved drug resistance prediction

Binding of Tryptophan Transfer RNA to Avian Myeloblastosis Virus Reverse Transcriptase". Proceedings of the National Academy of Sciences. 72 (7): 2525–2539

protease inhibitor, an integrase inhibitor, or an NNRTI. Nucleoside reverse transcriptase inhibitors (NRTIs) are considered the "backbone" of ART and 2 of

a side effect of antiretroviral drugs such as nucleoside analog reverse transcriptase inhibitors and protease inhibitors, which worsens with an increasingly

Mee, Andrew P (May 2003). "A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection

interstitial lung disease during clinical studies applying quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR. GRCh38: Ensembl release 89:

antiretroviral therapy agents like protease inhibitors and nonnucleoside reverse transcriptase inhibitors Its ability to transport the above substrates accounts

PhD student Carol W. Greider to the discovery of an enzyme with reverse transcriptase activity that was able to fill in the terminal ends of telomeres

test this mutation by immunohistochemistry. Other techniques like reverse-transcriptase PCR (RT-PCR) can also be used to detect lung cancers with an ALK