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Longer titles found: Telomerase reverse transcriptase (view)

searching for Reverse transcriptase 233 found (646 total)

alternate case: reverse transcriptase

Delavirdine (503 words) [view diff] exact match in snippet view article find links to article

Delavirdine (DLV) (brand name Rescriptor) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare. It is used as part

virus infection. It is a cytidine nucleoside analog and nucleoside reverse transcriptase inhibitor. that inhibits HIV-1 replication in vitro. During phase

Ateviridine is a non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV. Preparation of the pyridylpiperazine moiety

Elvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Achillion Pharmaceuticals, Inc. for the treatment of HIV

Fosdevirine is an experimental antiviral agent of the non-nucleoside reverse transcriptase inhibitor class that was studied for potential use in the treatment

research for the treatment of HIV/AIDS. It acts as a nucleoside reverse transcriptase inhibitor (NRTI). The drug was discovered by Raymond F. Schinazi

treatment of HIV/AIDS. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced

experimental agent for the treatment of HIV. It is a non-nucleoside reverse transcriptase inhibitor. While emivirine showed promising antiviral activity in

"Efficacy, safety, bone and metabolic effects of HIV nucleoside reverse transcriptase inhibitor BMS-986001 (AI467003): a phase 2b randomised, controlled

Racivir is an experimental nucleoside reverse transcriptase inhibitor (NRTI), developed by Pharmasset for the treatment of HIV. It is the enantiomer of

Doravirine, sold under the brand name Pifeltro, is a non-nucleoside reverse transcriptase inhibitor medication developed by Merck & Co. for use in the treatment

SPD754, sometimes abbreviated to ATC) is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV. It is structurally related to lamivudine

the brand name Vemlidy, is a hepatitis B virus (HBV) nucleotide reverse transcriptase inhibitor medication for the treatment of chronic hepatitis B virus

Lodenosine is a failed experimental agent for the treatment of HIV. Its development was discontinued on January 11, 2001. "Drug Profile: Lodenosine". AdisInsight

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications

Clevudine (INN) is an antiviral drug for the treatment of hepatitis B (HBV). It is already approved for HBV in South Korea and the Philippines. It is marketed

efficient reverse transcriptase as demonstrated in in vitro assays. The more controversial competing mechanism is an RNA/RT-based mechanism (reverse transcriptase

and when the virus has not developed resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) and integrase strand transfer inhibitors.

Capravirine was a non-nucleoside reverse transcriptase inhibitor which reached phase II trials before development was discontinued by Pfizer. Both phase

antiretroviral medication for the treatment of HIV/AIDS. It contains three reverse transcriptase inhibitors patented by GlaxoSmithKline and marketed by a joint venture

Dapivirine is a non-nucleoside reverse transcriptase inhibitor developed at Janssen Therapeutics (formerly Tibotec Therapeutics). The International Partnership

appears to be okay. Lamivudine and abacavir are both nucleoside reverse transcriptase inhibitors (NRTI). Abacavir/lamivudine was approved for medical

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) of HIV-1

1500) is drug used to treat HIV infection. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Elsulfavirine is a prodrug which is metabolized

transfer inhibitor (INSTI), and lamivudine, a nucleoside analogue reverse transcriptase inhibitor (NRTI). It is taken by mouth. It was approved for use

nucleoside reverse transcriptase inhibitor Nevirapine non-nucleoside reverse transcriptase inhibitor Stavudine nucleoside reverse transcriptase inhibitor

polymerases with improved activity. The binary structure of a TNA reverse transcriptase has also been solved by X-ray crystallography, revealing the importance

Jewish Americans, see Lists of Jewish Americans. David Baltimore, reverse transcriptase, Nobel Prize (1975) Baruj Benacerraf, immunologist, Nobel Prize

genome. These tags can be appended to gene specific primers for reverse transcriptase polymerase chain reaction (RT-PCR) experiments, circumventing genomic

biological activity of novel human immunodeficiency virus (HIV) reverse transcriptase inhibitors. Other software tools which help to model pharmacophores

end of the mRNA. The primer is allowed to anneal to the RNA and reverse transcriptase is used to synthesize cDNA from the RNA until it reaches the 5'

Microbiology at McGill University. His laboratory primarily studies HIV reverse transcriptase, the molecular basis for drug resistance, and gene therapy. He received

nucleoside reverse transcriptase inhibitor Nevirapine non-nucleoside reverse transcriptase inhibitor Zidovudine nucleoside reverse transcriptase inhibitor

applications include the discovery of new Myeloperoxidase ligands, HIV reverse transcriptase inhibitors, applications in anti-viral bio-activity profiling, the

The WHO Model List of Essential Medicines for Children (aka Essential Medicines List for Children or EMLc), published by the World Health Organization

and meiotic-specific antisense transcript complementary to the reverse transcriptase (RT) and ribonuclease A (RNaseA) genes of the proviral retrotransposon

other drugs in the same class. Emtricitabine (FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) that is a synthetic fluoro derivative of thiacytidine

analog reverse-transcriptase inhibitor Rilpivirine Non-nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleotide analog reverse-transcriptase

inhibitor (Ki = 2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. It was patented in

Non-nucleoside reverse transcriptase inhibitor Lamivudine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleoside reverse transcriptase inhibitor

predicted rho-independent transcription terminators, and microarray and reverse-transcriptase PCR experiments indicate that the S. coelicolor version is transcribed

Manufacturer Component Type Year approved Abacavir HIV Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox

Switzerland. The company currently markets 17 products: Nucleoside reverse transcriptase inhibitors (NRTIs): abacavir (brand name Ziagen) lamivudine (brand

is most widely cited for his involvement in creating a real-time reverse transcriptase PCR (RRT-PCR) assay based on the avian influenza virus matrix gene

failure and no known or suspected resistance to any non-nucleoside reverse transcriptase inhibitor or integrase inhibitor. "Dolutegravir / rilpivirine (Juluca)

epsilonretrovirus genus based on similarities of the gene coding for the reverse transcriptase conserved in retroviruses. The virus infects soft tissues of the

reverse transcriptase inhibitors (NNRTI) inhibit reverse transcriptase by binding to an allosteric site on it. Cessation of a non-nucleoside reverse transcriptase

with the help of a specific enzyme called reverse transcriptase. Retrotransposons that carry reverse transcriptase in their gene can trigger its own transposition

Institute would lead to the discovery of the first non-nucleoside reverse transcriptase inhibitor (NNRTI). It was also Janssen who would introduce him to

variety of these concepts while in the lab, such as Group ll Intron reverse transcriptase mechanisms or RNA sequencing. One of the first concepts surrounding

template. This reaction takes place at 25 °C. In the second step, reverse transcriptase synthesis extends the DNA oligonucleotides that have annealed to

Hartmann, K. (2017-08-02). "Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations

containing nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitor (PI), and non-nucleoside reverse transcriptase inhibitors (NNRTI).

Matsuura SE, So AG, Scott WA (2007). "Stable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding

reverse transcriptase inhibitors, rilpivirine and etravirine and was first to characterize the metabolism of the nonnucleoside reverse transcriptase inhibitor

inhibitor Lamivudine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleoside reverse transcriptase inhibitor Clinical data Other names

(CP, P03542) ORF V – P5: pro-pol (P03554): protease, bifunctional reverse transcriptase and RNaseH ORF VI – P6: transactivator/viroplasmin (P03559): inclusion

Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction". Drug Metabolism and Disposition. American

3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proceedings of the National Academy of Sciences of the United States

Different types of reverse transcriptase polymerases are available to suit different needs and reaction conditions. Reverse transcriptase enzymes commonly

validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with

Lamivudine/raltegravir Combination of Lamivudine Reverse-transcriptase inhibitor Raltegravir Integrase inhibitor Clinical data Trade names Dutrebis Routes

development of lipodystrophy is associated with specific nucleoside reverse transcriptase inhibitors (NRTI). Mitochondrial toxicity is postulated to be involved

contains numerous flavonoid compounds that have anti-microbial, anti-reverse transcriptase, and anti-inflammatory effects. Hutchinson, J. & Rendle, A. B. Flora

containing trifluoromethyl groups include efavirenz (Sustiva), an HIV reverse transcriptase inhibitor; fluoxetine (Prozac), an antidepressant; and celecoxib

Patrick Dunn, Steven Swallow, Zachary Kevin Sweeney, "Nonnucleoside reverse transcriptase inhibitors", issued 2008-08-02  "Drug Profile: Lasinavir". AdisInsight

contains numerous flavonoid compounds that have anti-microbial, anti-reverse transcriptase, and anti-inflammatory effects. In the past many species were described

Evaluation of the Efficacy of Once-Daily PI & Once-Daily Non-Nucleoside Reverse Transcriptase Inhibitor - Containing Therapy Combinations for Initial Treatment

730–6. doi:10.1016/j.lfs.2011.02.017. PMID 21356216. Non-nucleoside reverse-transcriptase inhibitors have been shown to both induce and inhibit CYP3A4. Hidaka

During her Ph.D, Rittinger studied human immunodeficiency virus reverse transcriptase. At MRC National Institute for Medical Research Rittinger studied

gynecologic malignancies and malignant effusions detected by nested reverse transcriptase-polymerase chain reaction". Laboratory Investigation. 82 (9): 1147–53

(simulation) Reproductive tract infection Respiratory tract infection Reverse-transcriptase inhibitor, a class of antiretroviral drug Ramp travel index, a measure

and 3' end sequences. Many of these IEPs, including LtrA, share a reverse transcriptase domain and a "Domain X". Maturase K (MatK) is a protein somewhat

inhibitor Etravirine (TMC125, tradename Intelence), a non-nucleoside reverse transcriptase inhibitor (NNRTI) Bedaquiline (TMC207/R207910, tradename Sirturo)

biological properties including: anti-tumor, antiviral activity (reverse transcriptase inhibitory activity), neuroprotection, cardioprotection, anti-inflammation

H.; Kim, N. G.; Huh, H.; Kim, J. (2004). "Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava"

Cytochrome P450 inhibitor Emtricitabine Reverse-transcriptase inhibitor Tenofovir disoproxil Reverse-transcriptase inhibitor Clinical data Trade names Stribild

in PAR-CLIP, or other types of errors that can be introduced by reverse transcriptase when it reads through the crosslink site in standard HITS-CLIP method

capture–enzyme-linked immunosorbent assay (MAC-ELISA) and viral RNA detection by reverse transcriptase (RT-PCR) can also be used to diagnose dengue fever. Dengue virus

TG; Kim, SH; Kim, NG; Huh, H; Kim, J (2004). "Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava"

system, referred to as DLV Delavirdine (DLV), a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare DNSSEC Lookaside Validation

of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". J. Biol. Chem

PMRT may refer to: Peak muscle resistance testing Paired multiplex reverse transcriptase PCR (PMRT-PCR) Pere Marquette Rail-Trail Progressive muscle relaxation

C22H26O5 may refer to: Calanolide A, an experimental non-nucleoside reverse transcriptase inhibitor Hydroxyestrone diacetate, a synthetic, steroidal estrogen

anti-viral drugs used to treat HIV, specifically nucleoside analog reverse transcriptase inhibitors (NRTIs), interfere with an enzyme needed in the production

multiple human cytochrome P450 mRNA molecules using competitive reverse transcriptase-PCR". DNA Cell Biol. 17 (3): 231–8. doi:10.1089/dna.1998.17.231

of Emtricitabine Nucleoside reverse transcriptase inhibitor Tenofovir disoproxil Nucleotide analogue reverse transcriptase inhibitor Clinical data Trade

Genvoya, Odefsey and GS 9883, as well as Merck's non-nucleoside reverse transcriptase inhibitor MK-1439 (Doravirine). Current studies include a study

Fipravirimat§ Protease Inhibitors (PI) (Discovery and development) Reverse-transcriptase inhibitors (RTIs) Combined formulations Abacavir/lamivudine#

to synthesize stavudine (d4T) and zalcitabine (ddC) - two other reverse-transcriptase inhibitors used in the treatment of HIV patients. Also during 1964

in vitro activation by Hsc70 and Hsp40 of duck hepatitis B virus reverse transcriptase, an assumed Hsp90 client protein". The Journal of Biological Chemistry

(2018). "A computational study for rational HIV-1 non-nucleoside reverse transcriptase inhibitor selection and the discovery of novel allosteric pockets

1432-1033.2003.03555.x Lorsch JR; Bartel DP; Szostak JW (1995). "Reverse transcriptase reads through a 2′–5′ linkage and a 2′-thiophosphate in a template"

Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor) Tipranavir (HIV

variability already present in HIV-1 (owing to its mutation-happy reverse transcriptase). Vif therefore acts via APOBEC3G to increase the likelihood of

inhibits viral development by interfering with DNA-polymerase and reverse transcriptase activity. In cyanobacteria and plants, SQDG is synthesized in two

A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase". AIDS. 11 (4): 534–6. PMID 9084803. Li L, Lu X, Peterson CA, Legerski

therapy (ART), nucleoside reverse transcriptase inhibitors (NRTIs), protease inhibitors (PI), and non-nucleoside reverse transcriptase inhibitors (NNRTIs) with

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75

"Genomic and genetic analysis of Bordetella bacteriophages encoding reverse transcriptase-mediated tropism-switching cassettes". Journal of Bacteriology.

as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase". Nucleic Acids Res. 8 (13): 2885–94. doi:10.1093/nar/8.13.2885

Sequencing for Genotyping of Human Immunodeficiency Virus Type 1 Reverse Transcriptase". J Clin Microbiol. 38 (7): 2715–2721. doi:10.1128/JCM.38.7.2715-2721

Vesanoid® 1996 – Released anti-viral chemotherapeutic agent Hivid® (HIV reverse transcriptase inhibitor) 1997 – Released HIV protease inhibitor Invirase® 1999

polyprotein, an Rnase H (RH) which splits the DNR-RNA hybrid, a reverse transcriptase (RT) which produces a cDNA copy of the transposons RNA and a DDE

of detection of circulating colorectal cancer cells using CGM2 reverse transcriptase-polymerase chain reaction assay". Surgery. 139 (4): 556–62. doi:10

5"-AAGCAGTGGTATCAACGCAGAGTACrGrG+G-3’) and Superscript II reverse transcriptase. Superscript II reverse transcriptase has additional terminal transferase activity

as "Crix belly", after indinavir (Crixivan). The Proteolysis Map Reverse-transcriptase inhibitor Discovery and development of NS5A inhibitors Discovery

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75

Hamosh A., Greider C. W. (2005). "Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita"

Management RTP – (i) Real-time Transport Protocol RT-PCR – (i) reverse transcriptase polymerase chain reaction (sometimes real-time polymerase chain

rapid identification of specific DNA viruses from the CSF, while Reverse transcriptase PCR is commonly used to identify RNA viruses in the CSF. The accuracy

nucleoside reverse transcriptase inhibitors (NRTIs), nucleotide reverse transcriptase inhibitors (NtRTIs), Non-nucleoside reverse transcriptase inhibitors

receptor antagonists Non-nucleoside reverse transcriptase inhibitors Nucleoside and nucleotide reverse transcriptase inhibitors PDE5 inhibitors Proton pump

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Archiv. 440 (5): 461–75

commonly seen in patients treated with thymidine analogue nucleoside reverse transcriptase inhibitors like zidovudine (AZT) and stavudine (d4T). The diagnosis

genome using virus-specific probes. Variations of PCR such as nested reverse transcriptase PCR and real time PCR can also be used to determine viral loads

pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis". Virchows Arch. 440 (5): 461–75

Matsuzuka F, et al. (2007). "Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic

"Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance". Science. 282 (5394): 1669–75

Harry V, Razvi H (February 2006). "Expression of human telomerase reverse transcriptase, Survivin, DD3 and PCGEM1 messenger RNA in archival prostate carcinoma

of nucleic acid-based techniques such as in-situ hybridization, reverse-transcriptase polymerase chain reaction, and nucleic acid microarrays for specialized

inosine to form N1-cyanoethylinosine (ce1I). This serves to stall reverse transcriptase and lead to truncated cDNA molecules. This was combined with deep-sequencing

development of non-nucleoside reverse-transcriptase inhibitors Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors Broadly neutralizing

Diaryltriazines and Diarylpyrimidines Are Highly Potent Nonnucleoside Reverse Transcriptase Inhibitors with Possible Applications as Microbicides, Antimicrob

the table below. In a technical comparison between quantitative reverse transcriptase PCR and digital PCR, the expression of the rat gabrd gene was examined

Berkhout B, Jebbink M, Zsíros J (1999). "Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus". J. Virol

Lewi P, Vanham G, Janssen P., In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus

antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid

Kollman PA (April 2005). "Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and

"Detection of human 11 beta-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform

with a DNA intermediate. Typically, the virus will use its own reverse transcriptase enzyme to create DNA from the RNA genome. The FeFV viral genome

et al. (2003). "Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation

Oricchio, Elisa; Grillo, Caterina; et al. (20 May 2008). "Endogenous reverse transcriptase as a mediator of ursolic acid's anti-proliferative and differentiating

anti-inflammatory drugs increase the antiretroviral activity of nucleoside reverse transcriptase inhibitors in HIV type-1-infected T-lymphocytes: role of multidrug

millitre sooner than those taking similarly potent non-nucleoside reverse transcriptase inhibitors or protease inhibitors. This statistically significant

MRP2/ABCC2, and MRP3/ABCC3 by nucleoside, nucleotide, and non-nucleoside reverse transcriptase inhibitors". Drug Metab. Dispos. 35 (3): 340–4. doi:10.1124/dmd

tyrosinase, TRP-1, and Trp-2 transcripts in human melanocytes by reverse transcriptase-competitive multiplex PCR--regulation by steroid hormones". J. Invest

PMID 12788881. Ikeguchi M, Hirooka Y, Kaibara N (Sep 2003). "Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled

A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase". AIDS. 11 (4): 534–6. PMID 9084803. Bochkareva E, Frappier L, Edwards

Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction". Drug Metabolism and Disposition. American

specific primer (GSP). The primer binds to the mRNA, and the enzyme reverse transcriptase adds base pairs to the 3' end of the primer to generate a specific

inhibits other important biological targets including the virus’ reverse transcriptase and the inhibition of cyclooxygenase and 5′-lipoxygenase. Avarol’s

Schematic: A tagged random hexamer primer is used to prime M-MuLV reverse transcriptase to generate aminoallyl dUTP- modified cDNA fragments in fixed cells

About 300 samples were seeded from 34 protein types including HIV Reverse Transcriptase Complex (an enzyme that is a chemical key to the replication of

such clusters, such as ‘‘EST, weakly similar to ORF2 contains a reverse transcriptase domain [H. sapiens],’’ are derived from the title of a characterized

throughout the genome. The LINEs contain a sequence that encodes a reverse transcriptase protein. This protein aids in copying the RNA transcripts of LINEs

through the G-less cassette. Park, JH; Magan, N (2014-11-12). "Reverse Transcriptase-Coupled Quantitative Real Time PCR Analysis of Cell-Free Transcription

ADP-ribosylation DNA repair negative regulation of telomerase RNA reverse transcriptase activity protein poly-ADP-ribosylation DNA ADP-ribosylation negative

There are various tests: Antigen determination Virus isolation Reverse transcriptase PCR as well as real-time RT-PCR Antibody determination through virus

of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer". The Journal of

Blobel G, Cerami A, Bukrinsky M (Oct 1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

X (2008). "Dynamic binding orientations direct activity of HIV reverse transcriptase". Nature. 453 (7192): 184–189. Bibcode:2008Natur.453..184A. doi:10

significantly reduced titres in the thorax. The genome is detectable by reverse transcriptase-polymerase chain reaction in the head, thorax, abdomen and wings

Capillary Dysplasia (Mutations in FoxF1) Mutations in telomerase reverse transcriptase (TERT) Mutations in telomerase RNA component (TERC) Mutations in

"Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase". Virus Research. 134 (1–2): 124–46. doi:10.1016/j.virusres.2007

Higashibata H, Fujiwara S (March 2012). "Mutations to create thermostable reverse transcriptase with bacterial family A DNA polymerase from Thermotoga petrophila

mechanisms of a number of available anti-HIV drugs prevent either viral reverse transcriptase enzyme or protease enzyme, allowing the virus to enter the cell

regulation of telomere capping positive regulation of telomerase RNA reverse transcriptase activity regulation of telomere maintenance RNA metabolic process

development of non-nucleoside reverse transcriptase inhibitors Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors Lederman

Popov S, Dubrovsky L, Lee MA, et al. (1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

S, Marcellin P, Lidereau R, Beaune P, de Waziers I (Sep 2007). "Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and

include Mediator Complex Subunit 12 (MED12) exon 2, Telomerase Reverse Transcriptase (TERT) promoter, and Retinoic Acid Receptor Alpha (RARA); important

determinants in the interaction between the RNA encapsidation signal and reverse transcriptase of avian hepatitis B viruses". Journal of Virology. 71 (7): 4971–4980

Propofol Epinephrine Propylene glycol (D-lactic acidosis) Nucleoside reverse-transcriptase inhibitors Abacavir/dolutegravir/lamivudine Emtricitabine/tenofovir

Fogli, L. K.; Algra, S.; Breault, D. T. (2010). "Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells".

3). EhLINE1 encode an endonuclease (EN) protein (in addition to reverse transcriptase and nucleotide-binding ORF1), which have similarity with bacterial

"Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is

Modiano, JF; Bagchi, A (2014). "Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan

Farnesyltransferase 2.6 GABA transaminase 2.7 Nucleotidyltransferase Integrase Reverse transcriptase Protein kinase Tyrosine kinase Janus kinase Hydrolase (EC 3) 3.1

2 (ORF 2) codes a protein which possesses both endonuclease and reverse transcriptase activities. This enables the LINE mRNA to be reverse-transcribed

is typically a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus two nucleoside analog reverse transcriptase inhibitors (NRTIs) Under research

and when the virus has not developed resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) and integrase strand transfer inhibitors. The

polyoxometalate-mediated inactivation of DNA polymerases: an analysis with HIV-1 reverse transcriptase indicates specificity for the DNA-binding cleft". Biochemical Journal

nucleic acid synthesis inhibitors MeSH D27.505.519.389.675.850 – reverse-transcriptase inhibitors MeSH D27.505.519.389.735 – phosphodiesterase inhibitors

KD; Loeb, LA (1997). "Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate". Mutation

is typically a non-nucleoside reverse transcriptase inhibitor (NNRTI) plus two nucleoside analog reverse transcriptase inhibitors (NRTIs) Under research

polymerase to replicate its RNA genome, but they discovered an enzyme, reverse transcriptase (in a mouse leukemia retrovirus), that converts RNA to DNA (involved

protein KIP binds telomerase by interacting with human telomerase reverse transcriptase". J. Biol. Chem. 279 (33): 34750–5. doi:10.1074/jbc.M401843200.

lab as an expert to study structure-function relationships of HIV reverse transcriptase. Becerra joined the National Eye Institute (NEI) as a visiting scientist

com. 27 September 2002. Retrieved 2022-02-02. "A Guide to HIV-1 Reverse Transcriptase and Protease Sequencing for Drug Resistance Studies" (PDF). hivdb

nucleic acid synthesis inhibitors MeSH D27.505.519.389.675.850 – reverse-transcriptase inhibitors MeSH D27.505.519.389.735 – phosphodiesterase inhibitors

refinement of CRISPR-Cas9 is called Prime Editing. This method links a reverse transcriptase to an RNA-guided engineered nuclease that only makes single-strand

A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase". AIDS. 11 (4): 534–6. PMID 9084803. Niu H, Erdjument-Bromage H

ISSN 0028-0836. PMID 1840648. S2CID 2713293. Lingner, J. (1997-04-25). "Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase". Science. 276 (5312):

biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors". Bioorg. Med. Chem. Lett. 16 (8): 2109–12. doi:10.1016/j

shown that highly active antiretroviral therapy-regimens including reverse transcriptase and potent protease inhibitors-are capable of suppressing HIV viral

via telomere lengthening positive regulation of telomerase RNA reverse transcriptase activity mRNA export from nucleus RNA metabolic process interleukin-12-mediated

Popov S, Dubrovsky L, Lee MA, et al. (1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

Popov S, Dubrovsky L, Lee MA, et al. (1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation"

Nobel Prize in Physiology & Medicine in 1975 for the discovery of reverse transcriptase. Has served as president of both the Rockefeller University and

protease inhibitor, an integrase inhibitor, or an NNRTI. Nucleoside reverse transcriptase inhibitors (NRTIs) are considered the "backbone" of ART and 2 of

protein-coding region, or open reading frame (ORF). Both gag and pol proteins are required for reverse transcriptase, which is essential to HIV1 replication.

include protease inhibitors used to treat HIV/AIDS and Hepatitis C, reverse-transcriptase inhibitors targeting HIV/AIDS, neuraminidase inhibitors targeting

Hüllermeier, E; Heider, D (2016). "Exploiting HIV-1 protease and reverse transcriptase cross-resistance information for improved drug resistance prediction

histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells". The Journal of

affect CYP3A or p-gp. When taking daclatasvir with non-nucleoside reverse transcriptase inhibitors, the dose of daclatasvir is increased to overcome CYP3A

2005 Converging Pattern, December 8 – 17, 2006 Fraser Taylor: Reverse Transcriptase, November 13 –February 13, 2006 Interstellar Low Ways, October 15

Viña, J.; Serrano, M.; Blasco, MA (November 2008). "Telomerase reverse transcriptase delays aging in cancer resistant mice". Cell. 135 (4): 609–622.

involved an intron invasion. Two definitive mechanisms of intron loss, reverse transcriptase-mediated intron loss (RTMIL) and genomic deletions, have been identified

histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells". J. Biol. Chem.

"Development and Evaluation of Serotype- and Group-Specific Fluorogenic Reverse Transcriptase PCR (Taq Man) Assays for Dengue Virus" (PDF). Journal of Clinical

PMID 10329640. Idriss H, Kawa S, Damuni Z, et al. (2000). "HIV-1 reverse transcriptase is phosphorylated in vitro and in a cellular system". Int. J. Biochem

inhibit HIV-1 infection through inhibition of HIV-1 protease & reverse transcriptase activity". Indian J Med Res. 137 (3): 540–548. PMC 3705663. PMID 23640562

Ihjima K, Yamada O (May 2005). "IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol

Sande Merle A (July 2002). "Emerging resistance to nonnucleoside reverse transcriptase inhibitors: a warning and a challenge". JAMA. 288 (2): 239–41. doi:10

Stackebrandt. Phylogenetic Analysis of the Genus Listeria Based on Reverse Transcriptase Sequencing of 16S rRNA. International Journal of Systematic and

pantoprazole, and lansoprazole). Rilpivirine, a non-nucleoside reverse transcriptase inhibitor used in the treatment of HIV, is contraindicated with

virus has been cloned and cDNA probes are available for diagnosis. Reverse transcriptase polymerase chain reaction (RT-PCR) methods have been developed for

cases of ependymoma recurrences. ERBB2, ERBB4, and human telomerase reverse transcriptase (TERT) gene expression promote tumor cell proliferation, contributing

Swaminathan S (January 2010). "Dose adjustment of the non-nucleoside reverse transcriptase inhibitors during concurrent rifampicin-containing tuberculosis

University. The patent claims to cover Stavudine, a nucleoside analog reverse-transcriptase (NARTI) active against HIV. This was the first acquisition ever

with a focus on HIV. He has shown that adherence to non-nucleoside reverse-transcriptase inhibitor HIV therapy has a linear dose-response pattern. He was

antiretroviral therapy despite extensive resistance within HIV-1 reverse transcriptase after the first virologic failure". BMC Infectious Diseases. 18

extracts have a mild effect on HIV-1 and HIV-2 strains, and HIV-1 reverse transcriptase. Clausamine E is cytotoxic to the human leukemia cell line HL60

protein while ORF2 encodes a protein containing endonuclease (EN) and reverse transcriptase (RT) activity, which nick a site in DNA, then produce a copy via

II receptor antagonist to treat hypertension Sustiva Efavirenz reverse transcriptase inhibitor for human immunodeficiency virus HIV Building 402 Reliance

Binding of Tryptophan Transfer RNA to Avian Myeloblastosis Virus Reverse Transcriptase". Proceedings of the National Academy of Sciences. 72 (7): 2525–2539

Mee, Andrew P (May 2003). "A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection

binds single-stranded telomere DNA and cooperates with telomerase reverse transcriptase to lengthen telomeres. Overexpression of SMG6 induces anaphase bridges

(April 1991). "Phylogenetic analysis of the genus Listeria based on reverse transcriptase sequencing of 16S rRNA". International Journal of Systematic Bacteriology

antiretroviral therapy agents like protease inhibitors and nonnucleoside reverse transcriptase inhibitors Its ability to transport the above substrates accounts

independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity". Nucleic Acids Research. 42 (1): 396–416. doi:10.1093/nar/gkt898

Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase". Journal of Virology. 92 (13). doi:10.1128/JVI.02203-17. PMC 6002700

test this mutation by immunohistochemistry. Other techniques like reverse-transcriptase PCR (RT-PCR) can also be used to detect lung cancers with an ALK

interstitial lung disease during clinical studies applying quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR. GRCh38: Ensembl release 89:

a single Yale patent with claims covering Stavudine, which is a reverse transcriptase inhibitor and the active ingredient in the drug Zerit. This was

sample that should be converted to complementary DNA (cDNA) using reverse transcriptase—a DNA polymerase that synthesizes a complementary DNA based on existing

telomerase. The catalytic subunit of telomerase called human telomerase reverse transcriptase (hTERT), represents a potential universal target for cancer immunotherapy

"Accuracy and cost description of rapid antigen test compared with reverse transcriptase-polymerase chain reaction for SARS-CoV-2 detection". Dan Med J.

DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR". Cancer Research. 55 (21): 5025–9. PMID 7585546. Lamerdin JE

DNA for cloning experiments may also be obtained from RNA using reverse transcriptase (complementary DNA or cDNA cloning), or in the form of synthetic

a side effect of antiretroviral drugs such as nucleoside analog reverse transcriptase inhibitors and protease inhibitors, which worsens with an increasingly

from small molecules can facilitate the synthesis of nucleoside reverse transcriptase inhibitors. For example, DERA was used in a mixture of five enzymes