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Longer titles found: Plasminogen activator Pla (view), Plasminogen activator inhibitor-1 (view), Plasminogen activator inhibitor-2 (view), Tissue-type plasminogen activator (view), Soluble urokinase plasminogen activator receptor (view)

searching for Plasminogen activator 227 found (311 total)

alternate case: plasminogen activator

Urokinase receptor (1,147 words) [view diff] exact match in snippet view article find links to article

The Urokinase receptor, also known as urokinase plasminogen activator surface receptor (uPAR) or CD87 (Cluster of Differentiation 87), is a protein encoded

Desmoteplase (1,346 words) [view diff] exact match in snippet view article find links to article

form of the alpha-1 isoform of DSPA (Desmodus rotundus salivary plasminogen activator). Desmoteplase, a chemical found in the saliva of vampire bats,

Euglobulin lysis time (239 words) [view diff] exact match in snippet view article find links to article

contains the important fibrinolytic factors fibrinogen, PAI-1, tissue plasminogen activator (tPA), plasminogen, and to a lesser extent α2-antiplasmin. The euglobulin

Kringle domain (431 words) [view diff] exact match in snippet view article find links to article

in some plasma proteins including prothrombin and urokinase-type plasminogen activator, which are serine proteases belonging to MEROPS peptidase family

Quebec platelet disorder (483 words) [view diff] exact match in snippet view article find links to article

characterized by large amounts of the fibrinolytic enzyme urokinase-type plasminogen activator (uPA) in platelets. This causes accelerated fibrinolysis (blood

SERBP1 (1,034 words) [view diff] exact match in snippet view article find links to article

Plasminogen activator inhibitor 1 RNA-binding protein (serbp1) is a protein that in humans is encoded by the SERBP1 gene. SERBP1 has been shown to interact

Ly6 (724 words) [view diff] exact match in snippet view article find links to article

Ly6 also known as lymphocyte antigen 6 or urokinase-type plasminogen activator receptor (uPAR) is family of proteins that share a common structure but

David Goeddel (278 words) [view diff] exact match in snippet view article find links to article

synthetic human insulin, human growth hormone, and human tissue plasminogen activator (tPA) for use in therapeutic medicine. Recruited by Bob Swanson

Suparnostic (1,116 words) [view diff] exact match in snippet view article find links to article

immunosorbent assay (ELISA) that measures the amount of soluble urokinase plasminogen activator receptor (suPAR) in blood. Elevated plasma suPAR levels have been

Hyperfibrinolysis (821 words) [view diff] exact match in snippet view article find links to article

for hyperfibrinolysis, alpha-2-plasmin inhibitor deficiency or plasminogen activator inhibitor type 1 (PAI-1) are very rare. The affected individuals

List of MeSH codes (D23) (8,039 words) [view diff] no match in snippet view article

The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

Intracameral injection (173 words) [view diff] exact match in snippet view article find links to article

intracameral injections. Intracameral injection of recombinant tissue plasminogen activator (r-TPA) has been found to be effective in treating the development

List of MeSH codes (D12.776.124) (3,780 words) [view diff] exact match in snippet view article

MeSH D12.776.124.125.662.768 – tissue plasminogen activator MeSH D12.776.124.125.662.884 – urinary plasminogen activator MeSH D12.776.124.400.405.440 – hemoglobin

Sandra J. F. Degen (2,369 words) [view diff] exact match in snippet view article find links to article

Degen worked under the mentorship of Edward Reich studying the plasminogen activator gene. Degen completed her postdoctoral training in 1985. In 1985

Frans Van de Werf (326 words) [view diff] exact match in snippet view article find links to article

with Désiré Collen to discover the clinical application of tissue plasminogen activator (tPA). Van de Werf was editor-in-chief of the European Heart Journal

National Institutes of Health Stroke Scale (4,263 words) [view diff] case mismatch in snippet view article find links to article

of Neurological Disorders and Stroke (NINDS) Recombinant Tissue Plasminogen Activator (rt-PA) for Acute Stroke Trial and was first published by neurologist

Thrombolytic Science International (159 words) [view diff] case mismatch in snippet view article find links to article

(the precursor form of urokinase) and a small dose of tPA [Tissue Plasminogen Activator]. TSI is developing its dual therapy as a potential treatment for

TFE3 (1,380 words) [view diff] exact match in snippet view article find links to article

2003). "Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional

Reperfusion therapy (3,470 words) [view diff] exact match in snippet view article find links to article

include streptokinase, urokinase, and alteplase (recombinant tissue plasminogen activator, rtPA). More recently, thrombolytic agents similar in structure

Posterior spinal artery syndrome (1,043 words) [view diff] exact match in snippet view article find links to article

can be developed. For instance, one study suggests that a tissue plasminogen activator (tPA) therapy intervention, commonly used in stroke patients, may

HLTF (984 words) [view diff] exact match in snippet view article find links to article

PMID 7876228. Descheemaeker K (1993). "On the regulation of the plasminogen activator inhibitor-1 gene expression". Verh. K. Acad. Geneeskd. Belg. 55

LRP1 (3,450 words) [view diff] exact match in snippet view article find links to article

functions in clearing proteases such as plasmin, urokinase-type plasminogen activator, and metalloproteinases, which contributes to prevention of cancer

Jochen Reiser (1,658 words) [view diff] exact match in snippet view article find links to article

diseases. Reiser discovered the role of suPAR (soluble urokinase plasminogen activator receptor) as a global, circulating risk factor for chronic kidney

Jadranka Lončarek (323 words) [view diff] exact match in snippet view article find links to article

dissertation in 2002 was titled The expression of the urokinase plasminogen activator gene in bladder carcinoma cell lines. Her doctoral advisor was Jasna

Catheter lock solution (884 words) [view diff] exact match in snippet view article find links to article

decrease of the use of thrombolytic agents like urokinase or tissue plasminogen activator (t-PA). Taurolidine/heparin (Defencath) was approved for medical

PGRMC1 (1,958 words) [view diff] exact match in snippet view article find links to article

drug, hormone and lipid metabolism. PGRMC1 also binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). However, its expression outside

ST14 (1,151 words) [view diff] exact match in snippet view article find links to article

activate hepatocyte growth factor/scatter factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane

Sex differences in stroke care (696 words) [view diff] case mismatch in snippet view article find links to article

with their male counterparts. The use of rt-PA (Recombinant Tissue Plasminogen Activator), a protein enzyme that helps break up blood clots, is a common

Mannose receptor (3,688 words) [view diff] exact match in snippet view article find links to article

α-chains, C-terminal propeptides of type I pro-collagens, and tissue plasminogen activator. Binding studies indicate that each liver sinusoidal endothelial

International Studies of Infarct Survival (509 words) [view diff] exact match in snippet view article find links to article

that compared the three thrombolytic drugs streptokinase, tissue plasminogen activator (tPA) and anistreplase to each other, and also compared the anticoagulant

Tranexamic acid (4,075 words) [view diff] exact match in snippet view article find links to article

potency (IC50 = 87 mM), and it can block the active-site of urokinase plasminogen activator (uPA) with high specificity (Ki = 2 mM), one of the highest among

LU domain (740 words) [view diff] exact match in snippet view article find links to article

proteins such as CD59 antigen, LYNX1, SLURP1, and SLURP2. Urokinase plasminogen activator surface receptor InterPro: IPR003631 Cell-surface glycoprotein Ly-6/CD59

Alpha-tocopherol transfer protein (909 words) [view diff] exact match in snippet view article find links to article

"Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells". Ann

Désiré Collen (1,303 words) [view diff] exact match in snippet view article find links to article

1980s and 1990s for the discovery of the potential of t-PA (tissue plasminogen activator) as a life-saving drug for patients with acute myocardial infarction

Proteases (medical and related uses) (1,343 words) [view diff] exact match in snippet view article

others rely on observations of anti-inflammatory activity. Tissue plasminogen activator (TPA) is a serine protease occurring in animals including humans

ITGB3BP (804 words) [view diff] exact match in snippet view article find links to article

regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081

Overall hemostatic potential (643 words) [view diff] exact match in snippet view article find links to article

generation in the presence of thrombin or tissue factor and tissue plasminogen activator (t-PA). It generates a fibrin time curve through the use of optical

Male accessory gland infection (646 words) [view diff] exact match in snippet view article find links to article

study has proposed that elevated levels of soluble urokinase-type plasminogen activator receptor (SuPAR) in seminal plasma might be useful as a marker for

Ultrasound-enhanced systemic thrombolysis (1,369 words) [view diff] exact match in snippet view article find links to article

treatment that works with the conventional thrombolytics such as tissue plasminogen activator (tPA). Typically, frequencies are in the megahertz (MHz) range,

LRP2 (2,606 words) [view diff] exact match in snippet view article find links to article

"Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes". The Journal of Biological

Thromboelastography (2,004 words) [view diff] exact match in snippet view article find links to article

clinical setting. A single, modified TEG assay with exogenous tissue plasminogen activator (tPA) demonstrated remarkable efficiency in unmasking patients'

Staphylokinase (460 words) [view diff] exact match in snippet view article find links to article

Collen D, Lijnen HR (1994). "Staphylokinase, a fibrin-specific plasminogen activator with therapeutic potential?" (PDF). Blood. 84 (3): 680–686. doi:10

Anakinra (2,148 words) [view diff] exact match in snippet view article find links to article

determined by blood levels of a protein called suPAR (soluble urokinase plasminogen activator receptor) of at least 6 ng per ml." In November 2022, the United

Erlizumab (424 words) [view diff] exact match in snippet view article find links to article

of an anti-CD18 antibody in conjunction with recombinant tissue plasminogen activator for acute myocardial infarction: limitation of myocardial infarction

Memorial Hermann–Texas Medical Center (949 words) [view diff] exact match in snippet view article find links to article

clot-busting drug tissue plasminogen activator (tPA). The 1995 paper announcing the results of the trial, titled "Tissue Plasminogen Activator for Acute Ischemic

Vascular endothelial growth factor B (1,558 words) [view diff] exact match in snippet view article find links to article

growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells". Proceedings of the National Academy

SLURP1 (1,212 words) [view diff] exact match in snippet view article find links to article

the gene encoding secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related protein-1 (SLURP-1) and description of five ancestral

Envoplakin (859 words) [view diff] exact match in snippet view article find links to article

S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope

Genetically modified bacteria (2,702 words) [view diff] exact match in snippet view article find links to article

treat some cancers, erythropoietin for anemic patients, and tissue plasminogen activator which dissolves blood clots. Outside of medicine they have been

Thrombus (3,261 words) [view diff] exact match in snippet view article find links to article

systemic fibrinolytic state and can lead to bleeding problems. Tissue plasminogen activator (tPA) is a different enzyme that promotes the degradation of fibrin

Joanna Wardlaw (1,332 words) [view diff] exact match in snippet view article find links to article

benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke

Senescence-associated secretory phenotype (4,600 words) [view diff] exact match in snippet view article find links to article

fragments, chemokines, and other bioactive factors. Soluble urokinase plasminogen activator surface receptor is part of SASP, and has been used to identify

List of medical abbreviations: T (0 words) [view diff] exact match in snippet view article find links to article

of pregnancy TOT transobturator tape TP total protein TPa tissue plasminogen activator TPN total parenteral nutrition TPR temperature, pulse, respiration

CKAP4 (1,499 words) [view diff] exact match in snippet view article find links to article

particular for surfactant protein A (SP-A) in lungs alveoli, tissue plasminogen activator (tPA) in vascular smooth muscle cells and for anti-proliferative

SERPINI2 (628 words) [view diff] exact match in snippet view article find links to article

involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members

P-selectin (2,589 words) [view diff] exact match in snippet view article find links to article

reported to be highly correlated to plasminogen activator inhibitor-1 activity and tissue plasminogen activator activity. P-selectin is found in endothelial

Cerebral infarction (3,074 words) [view diff] exact match in snippet view article find links to article

stroke centers, pharmacologic thrombolysis with the drug tissue plasminogen activator (tPA), is used to dissolve the clot and unblock the artery. Giving

KLK2 (1,089 words) [view diff] exact match in snippet view article find links to article

(1999). "Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1". Int. J. Cancer. 81 (3): 438–442. doi:10

Angiostatin (978 words) [view diff] exact match in snippet view article find links to article

integrins, annexin II, C-met receptor, NG2 proteoglycan, tissue-type plasminogen activator, chondroitin sulfate proteoglycans, and CD26. Additionally, smaller

CendR (590 words) [view diff] exact match in snippet view article find links to article

activated by proteolytic cleavage (e.g. by furin, urokinase type plasminogen activator, and other proteases of suitable substrate specificity). The CendR

Three-finger protein (1,449 words) [view diff] exact match in snippet view article find links to article

globular protein lymphocyte antigen 6 (LY6) family and the urokinase plasminogen activator receptor (uPAR). Other receptors with LU domains include members

Cerebral infarction (3,074 words) [view diff] exact match in snippet view article find links to article

stroke centers, pharmacologic thrombolysis with the drug tissue plasminogen activator (tPA), is used to dissolve the clot and unblock the artery. Giving

Genetics Institute (437 words) [view diff] exact match in snippet view article find links to article

recombinant human Factor VIII (Recombinate); as well as tissue plasminogen activator and erythropoetin that both involved costly, complex lawsuits over

Purpura (652 words) [view diff] exact match in snippet view article find links to article

Other studies suggest the local (cutaneous) activity of tissue plasminogen activator can be increased in psychogenic purpura, leading to substantial

Transcranial Doppler (3,305 words) [view diff] exact match in snippet view article find links to article

instantly. Various drugs (e.g. aspirin, streptokinase, and tissue plasminogen activator (TPA) in ascending order of effectiveness and cost) can reverse

Laminin subunit alpha-1 (1,008 words) [view diff] exact match in snippet view article find links to article

fibronectin contain binding domains for human plasminogen and tissue plasminogen activator". J. Biol. Chem. 268 (25): 18917–23. doi:10.1016/S0021-9258(17)46714-7

MIA PaCa-2 (240 words) [view diff] exact match in snippet view article find links to article

M; et al. (3 May 1977). "Purification and characterization of a plasminogen activator secreted by cultured human pancreatic carcinoma cells". Biochemistry

Oxygen diffusion-enhancing compound (750 words) [view diff] exact match in snippet view article find links to article

infarct ischemic strokes: A combination therapy study with tissue plasminogen activator". Brain Research. 1309: 136–145. doi:10.1016/j.brainres.2009.10

Thrombus perviousness (1,507 words) [view diff] exact match in snippet view article find links to article

predictor of early recanalization with intravenous tissue-type plasminogen activator. Stroke 2015. Santos EMM, Dankbaar JW, Treurniet KM, et al. Permeable

SPRR1A (576 words) [view diff] exact match in snippet view article find links to article

S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope

Pulmonary embolism (9,772 words) [view diff] exact match in snippet view article find links to article

cases may require thrombolysis using medication such as tissue plasminogen activator (tPA) given intravenously or through a catheter, and some may require

Limb infarction (998 words) [view diff] exact match in snippet view article find links to article

angiography should be performed. Thrombolysis using analogs of tissue plasminogen activator (tPA) may be used as an alternative or complement to surgery. Where

Ischemic cascade (742 words) [view diff] exact match in snippet view article find links to article

been tested in clinical trials, leading to the approval of tissue plasminogen activator (also known as tPA, t-PA, rtPA, Activase, or Alteplase or Actilyse)

Eric Topol (3,157 words) [view diff] exact match in snippet view article find links to article

was involved with the first patient who was administered tissue plasminogen activator (t-PA) in 1984, a genetically engineered protein. In 1996, he started

Frostbite (3,619 words) [view diff] exact match in snippet view article find links to article

revealed that iloprost alone or iloprost plus recombinant tissue plasminogen activator (rtPA) may decrease amputation rate in case of severe frostbite

Potato carboxypeptidase inhibitor (605 words) [view diff] exact match in snippet view article find links to article

thrombin-activatable fibrinolysis inhibitor potentiates tissue-type plasminogen activator-induced thrombolysis in a rabbit jugular vein thrombolysis model"

Cerebroprotectant (6,021 words) [view diff] exact match in snippet view article find links to article

tested in clinical trials to provide cerebroprotection. Tissue plasminogen activator (also known as tPA, t-PA, rtPA, Activase, or Alteplase or Actilyse)

Neurointensive care (1,565 words) [view diff] exact match in snippet view article find links to article

assistance, if necessary to maintain hemodynamic stability. Tissue plasminogen activator: Monitor patient who receive TPA for 24 hours for brain bleeds.

SPRR1B (744 words) [view diff] exact match in snippet view article find links to article

S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope

VEGFR1 (1,086 words) [view diff] exact match in snippet view article find links to article

growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells". Proceedings of the National Academy

RBP1 (1,213 words) [view diff] no match in snippet view article find links to article

retinoic acid receptor alpha in the stimulation of tissue-type plasminogen-activator gene expression in human endothelial cells". Eur. J. Biochem. 232

MSR1 (1,260 words) [view diff] exact match in snippet view article find links to article

binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway". J.

KLK4 (1,328 words) [view diff] exact match in snippet view article find links to article

prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase". Biochemistry. 40

IGFBP5 (904 words) [view diff] exact match in snippet view article find links to article

(1997). "Insulin-like growth factor binding protein-5 binds to plasminogen activator inhibitor-I". Endocrinology. 138 (7): 2972–8. doi:10.1210/endo.138

FAST (stroke) (1,009 words) [view diff] exact match in snippet view article

acronym was created to expedite administration of intravenous tissue plasminogen activator to patients within 3 hours of acute stroke symptom onset. The instruments

Matrix metallopeptidase 12 (1,157 words) [view diff] exact match in snippet view article find links to article

Resnati M, et al. (2003). "Metalloproteases cleave the urokinase-type plasminogen activator receptor in the D1-D2 linker region and expose epitopes not present

FOSL1 (1,074 words) [view diff] exact match in snippet view article find links to article

"Cell-type specific DNA-protein interactions at the tissue-type plasminogen activator promoter in human endothelial and HeLa cells in vivo and in vitro"

OmpT (1,367 words) [view diff] exact match in snippet view article find links to article

pestis and Salmonella enterica cleave the reactive center loop of plasminogen activator inhibitor 1". J. Bacteriol. 192 (18): 4553–61. doi:10.1128/JB.00458-10

Dextran (1,402 words) [view diff] exact match in snippet view article find links to article

fibrin[citation needed]). By inhibiting α-2 antiplasmin, dextran serves as a plasminogen activator, so possesses thrombolytic features. Outside of these features,

Noonan syndrome (4,257 words) [view diff] exact match in snippet view article find links to article

factor XII:C, and an imbalance of plasminogen activator inhibitor type-1 (PAI-1) and tissue plasminogen activator (t-PA) activity. It has been associated

CYP1B1 (1,185 words) [view diff] exact match in snippet view article find links to article

K, Dold KM, Greenlee WF (1991). "Targets for dioxin: genes for plasminogen activator inhibitor-2 and interleukin-1 beta". Science. 254 (5030): 415–8

Juan Asenjo (811 words) [view diff] exact match in snippet view article find links to article

purification of several proteins including alpha amylase, tissue plasminogen activator, monoclonal antibodies and virus-like particles. Recently his group

ANOS1 (644 words) [view diff] exact match in snippet view article find links to article

X-linked Kallmann's syndrome, with heparan sulphate and urokinase-type plasminogen activator". Biochemical Journal. 384 (Pt 3): 495–505. doi:10.1042/BJ20041078

Peripherally inserted central catheter (1,572 words) [view diff] exact match in snippet view article find links to article

occlusion, phlebitis and bleeding. Urokinase or low-dose tissue plasminogen activator (tPA) may be required to break down obstructions, depending on the

Cathepsin B (1,485 words) [view diff] exact match in snippet view article find links to article

matrix metalloproteinase, urokinase (serine protease urokinase plasminogen activator), and cathepsin D, and thus it has an essential position for the

PDGFD (793 words) [view diff] case mismatch in snippet view article find links to article

(2005). "Platelet-Derived Growth Factor D Is Activated by Urokinase Plasminogen Activator in Prostate Carcinoma Cells". Mol. Cell. Biol. 25 (14): 6279–88

CLEC3B (843 words) [view diff] exact match in snippet view article find links to article

(2003). "Tetranectin binds hepatocyte growth factor and tissue-type plasminogen activator". Eur. J. Biochem. 270 (8): 1850–4. doi:10.1046/j.1432-1033.2003

Randy Read (1,369 words) [view diff] exact match in snippet view article find links to article

J.; Pannekoek, H (2001). "Different structural requirements for plasminogen activator inhibitor 1 (PAI-1) during latency transition and proteinase inhibition

Mobile stroke unit (904 words) [view diff] exact match in snippet view article find links to article

Peterson ED, Schwamm LH (February 2011). "Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital

Protein superfamily (2,519 words) [view diff] exact match in snippet view article find links to article

(1fp7), exfoliatin toxin (1exf), HtrA protease (1l1j), snake venom plasminogen activator (1bqy), chloroplast protease (4fln) and equine arteritis virus protease

Index of oncology articles (5,119 words) [view diff] exact match in snippet view article find links to article

rattlesnake root – ravuconazole – rebeccamycin – recombinant tissue plasminogen activator – reconstructive surgeon – reconstructive surgery – recurrent cancer

Helga (Elga) De Vries (1,934 words) [view diff] exact match in snippet view article

diapedesis into the brain during inflammation is mediated by tissue-type plasminogen activator (tPA). Continuing to probe the ways that immune cells infiltrate

HNF1B (1,254 words) [view diff] exact match in snippet view article find links to article

LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells". Mol. Cell. Biol. 18 (8): 4698–706. doi:10

LYPD6B (657 words) [view diff] exact match in snippet view article find links to article

prototoxin, LYPD6B also belongs to the protein family of Ly-6/urokinase plasminogen activator receptor (Ly6/uPAR). It has a 3-fingered motif secondary structure

HGFAC (839 words) [view diff] exact match in snippet view article find links to article

relationship with blood coagulation factor XII, urokinase, and tissue-type plasminogen activator". Eur. J. Biochem. 258 (2): 355–61. doi:10.1046/j.1432-1327.1998

ZMYND8 (785 words) [view diff] exact match in snippet view article find links to article

PMID 9373149. Mahony D, Kalionis B, Antalis TM (1999). "Plasminogen activator inhibitor type-2 (PAI-2) gene transcription requires a novel NF-kappaB-like

Cathepsin L1 (1,705 words) [view diff] exact match in snippet view article find links to article

"Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L." FEBS Lett. 297

Brain ischemia (2,432 words) [view diff] exact match in snippet view article find links to article

For acute ischemic stroke, intravenous thrombolysis with tissue plasminogen activator (tPA) is recommended within 4.5 hours of symptom onset. In patients

Chemical chaperone (1,382 words) [view diff] exact match in snippet view article find links to article

enhancement by periplasmic expression is the disulfide bond-containing plasminogen activator variant (rPA). Folding of rPA is shown to increase when folding

PDGFC (1,369 words) [view diff] exact match in snippet view article find links to article

activation of latent platelet-derived growth factor CC by tissue plasminogen activator". J. Biol. Chem. 280 (29): 26856–62. doi:10.1074/jbc.M503388200

Caerphilly Heart Disease Study (3,775 words) [view diff] exact match in snippet view article find links to article

HF, Elwood PC (January 1998). "Fibrin D-dimer, tissue plasminogen activator, plasminogen activator inhibitor, and the risk of major ischaemic heart disease

HPN (gene) (827 words) [view diff] exact match in snippet view article

Vij R, Eigenbrot C, Kirchhofer D (Oct 2006). "Pro-urokinase-type plasminogen activator is a substrate for hepsin". The Journal of Biological Chemistry

ZFP36 (1,069 words) [view diff] exact match in snippet view article find links to article

Stasinopoulos S, Leedman P, Medcalf RL (2003). "Inherent instability of plasminogen activator inhibitor type 2 mRNA is regulated by tristetraprolin". J. Biol

Stroke (20,769 words) [view diff] exact match in snippet view article find links to article

ischemic stroke. Thrombolysis, such as with recombinant tissue plasminogen activator (rtPA), in acute ischemic stroke, when given within three hours

ATF1 (1,380 words) [view diff] exact match in snippet view article find links to article

LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells". Mol. Cell. Biol. 18 (8): 4698–706. doi:10

Chromosome 8 (1,978 words) [view diff] exact match in snippet view article find links to article

TONSL: encoding protein Tonsoku-like, DNA repair protein TPA: tissue plasminogen activator TRMT12: tRNA methyltransferase 12 homolog TRPS1: trichorhinophalangeal

Richard B. Hollis (1,214 words) [view diff] exact match in snippet view article find links to article

product launches for Protropin (human growth hormone) and tissue plasminogen activator (tPA), a drug for dissolving clots in people with strokes or heart

Ischemia (2,348 words) [view diff] exact match in snippet view article find links to article

intra-arterial infusion of a thrombolytic agent (e.g., recombinant tissue plasminogen activator (tPA), streptokinase, or urokinase). A percutaneous catheter inserted

Giant-cell carcinoma of the lung (4,910 words) [view diff] exact match in snippet view article find links to article

stimulating factor (G-CSF) GCCL has also been reported to produce plasminogen activator as a paraneoplastic phenomenon. Because of its rarity, there have

SPINT2 (1,145 words) [view diff] exact match in snippet view article find links to article

epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells". The Journal of Biological Chemistry

Center for Drug Evaluation and Research (1,213 words) [view diff] exact match in snippet view article find links to article

Biologics over whether to approve Genentech's Activase (tissue plasminogen activator) led to the split. In its original form, CDER was composed of six

Vsevolod Tkachuk (2,107 words) [view diff] exact match in snippet view article find links to article

metastasis. Research of the biological functions of urokinase-type plasminogen activator (uPA) Since early 90s V. A. Tkachuk and his colleagues (E. V. Parfyonova

Crocetin (1,505 words) [view diff] exact match in snippet view article find links to article

infarct ischemic strokes: A combination therapy study with tissue plasminogen activator". Brain Research. 1309: 136–145. doi:10.1016/j.brainres.2009.10

Transcranial pulsed ultrasound (1,104 words) [view diff] exact match in snippet view article find links to article

increased risk of hemorrhage with combined ultrasound and tissue plasminogen activator: results of a phase II clinical trial". Stroke. 36 (7): 1441–6.

Amniotic fluid embolism (2,593 words) [view diff] exact match in snippet view article find links to article

hyperfibrinolysis, which is likely to be due to elevated tissue plasminogen activator (tPA) and decreased total thrombin activatable fibrinolysis inhibitor

Diffusion Pharmaceuticals (1,056 words) [view diff] exact match in snippet view article find links to article

infarct ischemic strokes: A combination therapy study with tissue plasminogen activator". Brain Research. 1309: 136–145. doi:10.1016/j.brainres.2009.10

FGF4 (1,874 words) [view diff] exact match in snippet view article find links to article

effects of fibroblast growth factors on expression of genes of the plasminogen activator and insulin-like growth factor systems by human breast fibroblasts"

Protease (2,913 words) [view diff] exact match in snippet view article find links to article

antithrombin (which protects the body from excessive coagulation), plasminogen activator inhibitor-1 (which protects the body from inadequate coagulation

Retinoid X receptor beta (1,150 words) [view diff] no match in snippet view article find links to article

retinoic acid receptor alpha in the stimulation of tissue-type plasminogen-activator gene expression in human endothelial cells". European Journal of

Angiokinase inhibitors (1,445 words) [view diff] case mismatch in snippet view article find links to article

"'Angiokinase' – Molecular Weights of Proteins Representing a Perivascular Plasminogen Activator". Thrombosis et Diathesis Haemorrhagica. 26 (2): 411–3. ISBN 978-3-7945-0170-0

List of MeSH codes (D12.776) (7,397 words) [view diff] no match in snippet view article

The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

Genentech (2,877 words) [view diff] exact match in snippet view article find links to article

manufacturing 2004). 1987: Activase (alteplase): A recombinant tissue plasminogen activator (tPa) used to dissolve blood clots in patients with acute myocardial

Involucrin (1,482 words) [view diff] exact match in snippet view article find links to article

S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope

Diabetic cardiomyopathy (2,361 words) [view diff] exact match in snippet view article find links to article

superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation". Proc Natl

Plastic bronchitis (1,602 words) [view diff] exact match in snippet view article find links to article

triglyceride-enriched low-fat diets, intratracheal heparin, inhaled tissue plasminogen activator, and steroids have also been reported and have met with variable

Implantation (embryology) (5,859 words) [view diff] exact match in snippet view article

are;[citation needed] Embryo-derived histamine-releasing factor Tissue plasminogen activator as well as its inhibitors Estradiol β1-integrins Fibroblast growth

FGF5 (2,251 words) [view diff] exact match in snippet view article find links to article

effects of fibroblast growth factors on expression of genes of the plasminogen activator and insulin-like growth factor systems by human breast fibroblasts"

Cold injury (2,854 words) [view diff] exact match in snippet view article find links to article

amputation. Bone scanning can help determine the ability to use tissue plasminogen activator (tPA) for breaking up associated blood clots. In cases of suspected

Lacunar stroke (1,711 words) [view diff] exact match in snippet view article find links to article

subcortical dementia such as Binswanger disease. Typically, tissue plasminogen activator may be administered within 3 to 4.5 hours of stroke onset if the

Cold injury (2,854 words) [view diff] exact match in snippet view article find links to article

amputation. Bone scanning can help determine the ability to use tissue plasminogen activator (tPA) for breaking up associated blood clots. In cases of suspected

Livedo reticularis (2,544 words) [view diff] exact match in snippet view article find links to article

complex antibody Livedo vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity and prothrombin G20210A heterozygosity

Deoxyribonuclease (3,220 words) [view diff] exact match in snippet view article find links to article

properties. Furthermore, recent studies show that intrapleural tissue plasminogen activator (tPA), a protein that is responsible for the breakdown of blood

FGF5 (2,251 words) [view diff] exact match in snippet view article find links to article

effects of fibroblast growth factors on expression of genes of the plasminogen activator and insulin-like growth factor systems by human breast fibroblasts"

Purpura fulminans (2,846 words) [view diff] exact match in snippet view article find links to article

JA, Pérez JL, Serrano M, Rocha E (August 1990). "Types 1 and 2 plasminogen activator inhibitor and tumor necrosis factor alpha in patients with sepsis"

Ischemia-reperfusion injury of the appendicular musculoskeletal system (1,486 words) [view diff] exact match in snippet view article find links to article

1186/s12967-016-1055-x. PMC 5080762. PMID 27784306. Wu, J.; et al. (2015). "Plasminogen activator inhibitor-1 inhibits angiogenic signaling by uncoupling vascular

Omptin (1,329 words) [view diff] exact match in snippet view article find links to article

pestis and Salmonella enterica cleave the reactive center loop of plasminogen activator inhibitor 1". Journal of Bacteriology. 192 (18): 4553–4561. doi:10

PA clan of proteases (1,709 words) [view diff] exact match in snippet view article find links to article

exfoliatin toxin (PDB: 1exf), HtrA protease (PDB: 1l1j), snake venom plasminogen activator (PDB: 1bqy), chloroplast protease (PDB: 4fln) and equine arteritis

Envelope glycoprotein GP120 (2,547 words) [view diff] exact match in snippet view article find links to article

apoptosis of neuronal cells by inhibiting levels of furin and tissue plasminogen activator, enzymes responsible for converting pBDNF to mBDNF. gp120 induces

Andreas Kjær (scientist) (1,307 words) [view diff] exact match in snippet view article

first-in-human clinical use. Examples include first-in-humans with urokinase plasminogen activator receptor (uPAR)-PET, a marker of cancer aggressiveness (68Ga-NOTA-AE105

NFKB1 (2,363 words) [view diff] exact match in snippet view article find links to article

regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor". J. Cell Sci. 115 (Pt 20): 3879–88. doi:10.1242/jcs.00081

Plague (disease) (3,618 words) [view diff] exact match in snippet view article

Gardner D, Long D, Hinnebusch B (2006). "Role of Yersinia pestis plasminogen activator in the incidence of distinct septicemic and bubonic forms of flea-borne

Infrared sensing in vampire bats (2,139 words) [view diff] exact match in snippet view article find links to article

Leslie A.; Liberles, David A. (2009). "Keeping the blood flowing – plasminogen activator genes and feeding behavior in vampire bats". Naturwissenschaften

List of diseases (P) (1,908 words) [view diff] exact match in snippet view article

Plasmacytoma anaplastic Plasmalogenes synthesis deficiency isolated Plasminogen activator inhibitor type 1 deficiency, congenital Plasminogen deficiency,

Linda C. Meade-Tollin (928 words) [view diff] exact match in snippet view article find links to article

"Expression of multiple matrix metalloproteinases and urokinase type plasminogen activator in cultured Kaposi sarcoma cells". Acta Histochemica. 101 (3): 305–316

Calciphylaxis (2,870 words) [view diff] exact match in snippet view article find links to article

include one or more of the following: Clot-dissolving agents (tissue plasminogen activator) Maggot larval debridement Correction of the underlying plasma calcium

Dense MCA sign (745 words) [view diff] exact match in snippet view article find links to article

initiation of treatment, such as intravenous thrombolysis (e.g., tissue plasminogen activator, tPA) or endovascular thrombectomy. Presence of the dense MCA sign

EPAS1 (2,685 words) [view diff] exact match in snippet view article find links to article

novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression". The Journal of Biological Chemistry

Toxic epidermal necrolysis (2,603 words) [view diff] exact match in snippet view article find links to article

WJ, Shih, R, Rosenbaum, S, Vilke, GM (December 2012). "Tissue plasminogen activator and stroke: review of the literature for the clinician". The Journal

Protease-activated receptor 2 (2,715 words) [view diff] exact match in snippet view article find links to article

of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates". The Journal of Biological Chemistry. 275 (34): 26333–42

Biopharmaceutical (2,900 words) [view diff] exact match in snippet view article find links to article

factors (Factor VIII and Factor IX) Thrombolytic agents (tissue plasminogen activator) Hormones (insulin, glucagon, growth hormone, gonadotrophins) Haematopoietic

Immunosuppressive drug (3,379 words) [view diff] exact match in snippet view article find links to article

various inflammatory mediators (lysosomal enzymes, cytokines, tissue plasminogen activator, chemokines, etc.) from neutrophils, macrophages, and mastocytes

Endoglin (2,845 words) [view diff] exact match in snippet view article find links to article

Smad1/5/8-dependent inhibitor of DNA binding 1 expression and Smad2/3-dependent plasminogen activator inhibitor I had a reduction in expression and cell proliferation

Opeolu Adeoye (621 words) [view diff] exact match in snippet view article find links to article

Khatri; Dawn Kleindorfer (2 June 2011). "Recombinant tissue-type plasminogen activator use for ischemic stroke in the United States: a doubling of treatment

Senolytic (2,027 words) [view diff] exact match in snippet view article find links to article

and the experimental small molecule navitoclax. Soluble urokinase plasminogen activator surface receptor have been found to be highly expressed on senescent

Tumor-associated macrophage (2,510 words) [view diff] exact match in snippet view article find links to article

factor α (TNFα), basic fibroblast growth factor, urokinase-type plasminogen activator, adrenomedullin, and semaphorin 4D. Moreover, cytokines produced

3K3A-Activated Protein C (353 words) [view diff] case mismatch in snippet view article find links to article

Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic

Cocaine intoxication (4,221 words) [view diff] exact match in snippet view article find links to article

adenosine diphosphate-mediated increase in platelet aggregation. Plasminogen activator inhibitor is also increased following cocaine use, thereby promoting

Growth hormone deficiency (3,064 words) [view diff] exact match in snippet view article find links to article

particularly raised LDL cholesterol Increased levels of fibrinogen and plasminogen activator inhibitor Cardiac dysfunction, including a thickened intima media

Center for Biologics Evaluation and Research (1,627 words) [view diff] exact match in snippet view article find links to article

Biologics over whether to approve Genentech's Activase (tissue plasminogen activator), led to the split. CBER was declared the primary agency for HIV/AIDS-related

LDL-receptor-related protein-associated protein (2,608 words) [view diff] exact match in snippet view article find links to article

mediates the cellular catabolism of lipoprotein lipase and urokinase-plasminogen activator inhibitor type I complexes". The Journal of Biological Chemistry

Uterine atony (3,241 words) [view diff] exact match in snippet view article find links to article

the placenta. Local hemostatic factors like tissue factor type-1 plasminogen activator inhibitor and platelets and clotting factors aid in stopping the

Angiotensin (3,171 words) [view diff] exact match in snippet view article find links to article

FP, Ursi M, Cerullo G (August 1999). "Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells". Kidney

Neuroprotection (4,030 words) [view diff] exact match in snippet view article find links to article

in clinical trials, leading to the regulatory approval of tissue plasminogen activator in several countries, and the approval of edaravone in Japan. Nerinetide

Coley's toxins (2,327 words) [view diff] exact match in snippet view article find links to article

Sukhatme V (2005). "Coley's toxin revisited: immunotherapy or plasminogen activator therapy of cancer?". J Thromb Haemost. 3 (3): 424–7. doi:10.1111/j

Liver regeneration (2,466 words) [view diff] exact match in snippet view article find links to article

epithelial cells to express an increased activity of urokinase plasminogen activator (uPA). Increased uPA activity initiates conversion of plasminogen

Francesco Blasi (1,331 words) [view diff] exact match in snippet view article find links to article

binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes". Proceedings of the National

Vampire bat (4,331 words) [view diff] case mismatch in snippet view article find links to article

skull in a museum, they're that sharp" Hawkey, Christine (1966). "Plasminogen Activator in Saliva of the Vampire Bat Desmodus rotundus". Nature. 211 (5047):

Histidine-rich glycoprotein (2,243 words) [view diff] exact match in snippet view article find links to article

"Familial association of high levels of histidine-rich glycoprotein and plasminogen activator inhibitor-1 with venous thromboembolism". The Journal of Laboratory

HMGB1 (3,178 words) [view diff] exact match in snippet view article find links to article

Rauvala H (September 1991). "Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen

Acute limb ischaemia (2,626 words) [view diff] exact match in snippet view article find links to article

main thrombolytic chemical. More recently, drugs such as tissue plasminogen activator, urokinase, and anistreplase have been used in their place. Mechanical

Growth differentiation factor-9 (3,324 words) [view diff] exact match in snippet view article find links to article

induces hyaluronanic synthase 2 (Has2) and suppresses urokinase plasminogen activator (uPA) mRNA synthesis in granulosa cells. This allows an extracellular

Genetically modified animal (10,789 words) [view diff] exact match in snippet view article find links to article

proteins in their milk were mice, engineered to produce human tissue plasminogen activator in 1987. The first genetically modified animal to be commercialised

Cerebrovascular disease (4,194 words) [view diff] case mismatch in snippet view article find links to article

(2015). "Comparison of Therapeutic Effect of Recombinant Tissue Plasminogen Activator by Treatment Time after Onset of Acute Ischemic Stroke". Scientific

Molecular cloning (4,017 words) [view diff] exact match in snippet view article find links to article

administered to assist in a life-threatening emergency (e.g. tissue plasminogen activator, used to treat strokes), (3) recombinant subunit vaccines, in which

Dysfibrinogenemia (3,248 words) [view diff] exact match in snippet view article find links to article

lysis: The Aα fibrin chain formed from fibrinogen binds tissue plasminogen activator, an agent that breaks down blood clots to participate thereby in

Formyl peptide receptor 2 (4,378 words) [view diff] exact match in snippet view article find links to article

cleaved soluble fragments of UPARAP which is the Urokinase-type plasminogen activator receptor (uPAR), D2D3(88–274) and uPAR(84–95) (pro-inflammatory);

List of enzymes (3,650 words) [view diff] exact match in snippet view article find links to article

37) Factor XII (EC 3.4.21.38) Proteinase K (EC 3.4.21.64) Tissue plasminogen activator (EC 3.4.21.68) Protein C (EC 3.4.21.69) Category:EC 3.4.22 Separase

Pathophysiology of multiple sclerosis (9,018 words) [view diff] exact match in snippet view article find links to article

coexpressed HLA-DR and VCAM-1, some others HLA-DR and urokinase plasminogen activator receptor, and others HLA-DR and ICAM-1. The damaged white matter

Common vampire bat (3,144 words) [view diff] case mismatch in snippet view article find links to article

C.; Schleuning, W.; Medcalf, R. (2003). "Vampire Bat Salivary Plasminogen Activator (Desmoteplase) A Unique Fibrinolytic Enzyme That Does Not Promote

List of recombinant proteins (2,322 words) [view diff] exact match in snippet view article find links to article

a DNase sold under the trade name Pulmozyme by Genentech Tissue plasminogen activator (TPA) Activase by Genentech Glucocerebrosidase: Ceredase by Genzyme

Therapeutic ultrasound (3,434 words) [view diff] exact match in snippet view article find links to article

Transcranial ultrasound is being tested for use in aiding tissue plasminogen activator treatment in stroke patients in the procedure called ultrasound-enhanced

Thrombosis (4,729 words) [view diff] exact match in snippet view article find links to article

by administering thrombolytic drugs including recombinant tissue plasminogen activator, which enhances the normal destruction of blood clots by the body's

S-Nitrosylation (2,247 words) [view diff] exact match in snippet view article find links to article

Mullins M, et al. (September 1992). "S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme"

AOC3 (3,002 words) [view diff] exact match in snippet view article find links to article

predict the appearance of parenchymal hemorrhages after tissue plasminogen activator treatment due to the transmigration of inflammatory cells into ischaemic

AP-1 transcription factor (4,614 words) [view diff] exact match in snippet view article find links to article

(AP-1) inhibits high glucose- and angiotensin II-induced type 1 plasminogen activator inhibitor (PAI-1) gene expression in cultured human vascular smooth

List of human clusters of differentiation (492 words) [view diff] exact match in snippet view article find links to article

to as the urokinase type plasminogen activator receptor, provides a binding point for urokinase type plasminogen activator CD88 C5a receptor CD89 FcalphaRI

SNED1 (2,400 words) [view diff] exact match in snippet view article find links to article

variant i and conserved domain CCP are >99% structurally similar to t-plasminogen activator (PLAT). PLAT is secreted by vascular endothelial cells and acts

History of biotechnology (4,810 words) [view diff] exact match in snippet view article find links to article

growth hormone, hepatitis B vaccine, alpha-interferon, and tissue plasminogen activator (TPa), for lysis of blood clots. By the end of the 1990s, however

Genetically modified organism (24,732 words) [view diff] exact match in snippet view article find links to article

mice in 1987. The mice were engineered to produce human tissue plasminogen activator, a protein involved in breaking down blood clots. In 1983, the first

IGFBP3 (4,717 words) [view diff] exact match in snippet view article find links to article

"Prognostic significance of growth factors and the urokinase-type plasminogen activator system in pancreatic ductal adenocarcinoma". Pancreas. 36 (2): 160–167

Anoxic depolarization in the brain (2,385 words) [view diff] exact match in snippet view article find links to article

a clot-dissolving, genetically-engineered enzyme called tissue plasminogen activator, which must be administered within 9 hours of the onset of symptoms

Katerina Akassoglou (1,923 words) [view diff] case mismatch in snippet view article find links to article

Keith W.; Degen, Jay L.; Strickland, Sidney (2000-05-29). "Tissue Plasminogen Activator–Mediated Fibrinolysis Protects against Axonal Degeneration and Demyelination

Yersinia pestis (6,736 words) [view diff] exact match in snippet view article find links to article

of the virulence of the pigmentation-deficient and pigmentation-/plasminogen activator-deficient strains of Yersinia pestis in non-human primate and mouse

June 1980 (10,602 words) [view diff] exact match in snippet view article find links to article

recombinant tissue plasminogen activator for dissolving blood clots. U.S. Patent No. 4,751,603 was granted on June 21, 1988 for "Plasminogen activator and pharmaceutical

Stroke center (1,913 words) [view diff] exact match in snippet view article find links to article

stroke centers (PSCs) are associated with greater rates of tissue plasminogen activator use and improved outcomes." The United States has over a thousand

Hypertrophic cardiomyopathy (8,821 words) [view diff] exact match in snippet view article find links to article

have already experienced a clot. Thrombolytic agents (e.g., tissue plasminogen activator) have been used with some success to break down existing aortic

S100A10 (4,728 words) [view diff] exact match in snippet view article find links to article

be presented on the cell surface as a receptor for tissue-type plasminogen activator (tPA) and plasminogen. Plasmin production by many cells is dependent

Sepsis (13,631 words) [view diff] exact match in snippet view article find links to article

outcomes. A 2012 systematic review found that soluble urokinase-type plasminogen activator receptor (SuPAR) is a nonspecific marker of inflammation and does

Migrainous infarction (2,628 words) [view diff] exact match in snippet view article find links to article

streptokinase is not recommended. Alteplase is a recombinant tissue plasminogen activator which enhances the conversion of plasminogen into plasmin to aid

Myocardial infarction (13,826 words) [view diff] exact match in snippet view article find links to article

normally dissolve blood clots. These medications include tissue plasminogen activator, reteplase, streptokinase, and tenecteplase. Thrombolysis is not

History of genetic engineering (6,419 words) [view diff] exact match in snippet view article find links to article

proteins in their milk were mice, engineered to produce human tissue plasminogen activator. This technology was applied to sheep, pigs, cows and other livestock

Jonathan Stamler (3,625 words) [view diff] exact match in snippet view article find links to article

Singel, D; Loscalzo, J (1992-09-01). "S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme"

Microvesicle (6,074 words) [view diff] exact match in snippet view article find links to article

including matrix metalloproteinase 2 (MMP-2), MMP-9, and urokinase-type plasminogen activator (uPA). By releasing these proteases, tumor cells can degrade the

Cardiovascular disease (15,122 words) [view diff] exact match in snippet view article find links to article

MI, strategies using aspirin, atenolol, streptokinase or tissue plasminogen activator have been compared for quality-adjusted life-year (QALY) in regions

Breast cancer (15,802 words) [view diff] exact match in snippet view article find links to article

for predicting response to therapeutic regimens, and urokinase plasminogen activator, PA1-1 and SCD1 for assessing prognosis.[medical citation needed]

List of MeSH codes (D08) (15,232 words) [view diff] exact match in snippet view article

– tissue plasminogen activator MeSH D08.811.277.656.300.760.895 – trypsin MeSH D08.811.277.656.300.760.910 – urinary plasminogen activator MeSH D08.811

Interventional radiology (13,270 words) [view diff] exact match in snippet view article find links to article

the brain is blocked. A clot-busting medication such as tissue plasminogen activator (t-PA) can be used in a controlled hospital setting to dissolve

Patrick Lyden (2,464 words) [view diff] exact match in snippet view article find links to article

Neurological Disorders and Stroke rt-PA Stroke Study Group (1995). "Tissue plasminogen activator for acute ischemic stroke". The New England Journal of Medicine

COVID-19 drug repurposing research (14,913 words) [view diff] exact match in snippet view article find links to article

determined by blood levels of a protein called suPAR (soluble urokinase plasminogen activator receptor) of at least 6 ng per ml." Drugs with immune modulating

Oxford–AstraZeneca COVID-19 vaccine (17,125 words) [view diff] exact match in snippet view article find links to article

coding sequence of SARS-CoV-2 spike protein along with a tissue plasminogen activator (tPA) leader sequence. The adenovirus is called replication-deficient

Telehealth (21,078 words) [view diff] exact match in snippet view article find links to article

Jabbour P, Gonzalez LF, et al. (October 2013). "Intravenous tissue plasminogen activator administration in community hospitals facilitated by telestroke

Zanvil A. Cohn (4,965 words) [view diff] exact match in snippet view article find links to article

139:1228-1248. With S. Gordon and J. C. Unkeless. Induction of macrophage plasminogen activator by endotoxin stimulation and phagocytosis. Evidence for a two-stage

Long-term effects of alcohol (16,937 words) [view diff] exact match in snippet view article find links to article

promotes clot formation, while it increases levels of tissue type plasminogen activator, an enzyme that helps dissolve clots. These changes were estimated

Developmental bioelectricity (17,264 words) [view diff] exact match in snippet view article find links to article

suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer". Oncogene. 32 (18): 2282–2291, 2291.e1–7

Plasma gelsolin (9,121 words) [view diff] exact match in snippet view article find links to article

PMID 9265648. Vartanian, Amalia A (March 2003). "Gelsolin and plasminogen activator inhibitor-1 are Ap3A-binding proteins". The Italian Journal of Biochemistry

Side effects of bicalutamide (15,729 words) [view diff] exact match in snippet view article find links to article

nonsteroidal antiandrogen Casodex on lipoproteins, fibrinogen and plasminogen activator inhibitor in patients with benign prostatic hyperplasia". Eur Urol

List of OMIM disorder codes (18,877 words) [view diff] exact match in snippet view article find links to article

182230; HESX1 Plamoplantar keratoderma, epidermolytic; 144200; KRT1 Plasminogen activator inhibitor, type I; 613329; PAI1 Platelet disorder, familial, with