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searching for Peptide-loading complex 12 found (19 total)

HLA-A (3,419 words) [view diff] no match in snippet view article find links to article

TAP then binds to the peptide loading complex along with another protein, called tapasin. At this point the peptide loading complex consists of HLA-A (heavy

TAP2 (1,208 words) [view diff] no match in snippet view article find links to article

reticulum-Golgi intermediate compartment membrane MHC class I peptide loading complex Biological process adaptive immune response immune system process

TAP1 (1,215 words) [view diff] no match in snippet view article find links to article

reticulum-Golgi intermediate compartment membrane MHC class I peptide loading complex Biological process defense response adaptive immune response immune

Cross-presentation (2,159 words) [view diff] no match in snippet view article find links to article

peptides are loaded onto MHC class I molecules with the help of the peptide loading complex and chaperone proteins such as beta-2 microglobulin, ERAP, tapasin

Robert Tampé (1,287 words) [view diff] exact match in snippet view article find links to article

Trowitzsch S, Moeller A, Tampé R (2017): Structure of the human MHC-I peptide-loading complex. Nature 551, 525–8. doi:10.1038/nature24627 Thomas C, Tampé R (2017):

Antigen presentation (1,674 words) [view diff] exact match in snippet view article find links to article

TAP, tapasin, MHS Class 1, ERp57, and calreticulin is called the peptide-loading complex (PLC). Peptides are loaded to MHC-I peptide binding groove between

Immunoevasin (1,219 words) [view diff] exact match in snippet view article find links to article

processing mechanism, TAP-independent peptide presentation, MHC I peptide-loading complex (PLC)-independent antigen presentation pathways, cross-presentation

Beta-2 microglobulin (2,118 words) [view diff] no match in snippet view article find links to article

recycling endosome membrane tertiary granule lumen MHC class I peptide loading complex Biological process positive regulation of receptor-mediated endocytosis

Calnexin (2,214 words) [view diff] exact match in snippet view article find links to article

folded state. After the β2-microglobulin binds to the MHC class I peptide-loading complex (PLC), calreticulin and ERp57 take over the job of chaperoning

HLA-G (3,061 words) [view diff] no match in snippet view article find links to article

upregulated in cancers. Peptides are connected to HLA-G by the peptide loading complex in the endoplasmic reticulum. HLA-G plays a role in immune tolerance

Heat shock protein (5,541 words) [view diff] no match in snippet view article find links to article

important - calreticulin binds peptides and together with gp96 form peptide loading complex for MHCI. This handing over with peptides is important, because

Cluster of Excellence Frankfurt Macromolecular Complexes (15,449 words) [view diff] exact match in snippet view article find links to article

chaperone and editing TAPBPR–MHC I complex and the human MHC-I peptide-loading complex. Antigenic peptide recognition on TAP was resolved by DNP-enhanced