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searching for Oral administration 296 found (896 total)

alternate case: oral administration

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and naproxen among others. It is available in some countries for oral administration. A transdermal preparation was approved for sale in Japan in January

aggregate, as well as providing tensile strength to the tissue. Oral administration of native type II collagen induces oral tolerance to pathological

Talcosis can also arise from the injection of drugs intended for oral administration, as talc is present in many tablets and capsules that are used intravenously

with peak plasma concentrations not reached until 2.5 hours after oral administration, and its O-desethyl metabolite Ro41-3290 is also active with a half-life

measuring cups are used by patients to measure liquid medicaments for oral administration. Glass and borosilicate conical measures are commonly used when compounding

limited to Aspirin. Any aspirin-containing product intended for oral administration by humans Furniture polish. Non-emulsion type liquid furniture polishes

properties. Peak plasma rates are achieved in around 2,5 hours after oral administration. The elimination half-life is between approximately 2–4 hours. Bentazepam

coordination impairing properties. Pinazepam is rapidly absorbed after oral administration. The main active metabolites of pinazepam are depropargylpinazepam

conversion ratio 0.891, molecular weight 335.8) was available only for oral administration for malignant pain and for maintenance of those habituated to morphine;

flutemazepam was the most rapid-acting compound of the series via oral administration, with noticeable sedative-hypnotic effects beginning 10-15 minutes

Erythromycyclamine retains the antibacterial properties of erythromycin oral administration. The prodrug, dirithromycin, is provided as enteric coated tablets

affinity 5-HT1D receptor antagonist. PNU-142633 is well tolerated after oral administration. It was an interesting candidate due to its greater affinity for

reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after two to four weeks or longer. Patients

AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral administration. Beginning in 2007, it underwent phase I clinical trials for the

tolerability, and a pharmacokinetic profile compatible with once a day oral administration. Phase II clinical trials are currently underway, making S1RA the

preparations are also in the form of sublingual drops and tablets for oral administration. Nicocodeine is approximately the same strength as hydrocodone; it

delaying in gastric emptying in mice and rats following subcutaneous or oral administration. Bevenopran Eluxadoline Methylnaltrexone Naldemedine Janku F, Johnson

methyl transferase EZH2, with potential antineoplastic activity. Upon oral administration, tazemetostat selectively inhibits the activity of both wild-type

used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors)

agonist on human 5-HT6 receptors (which are constitutively active). Oral administration of E-6837 reduced food intake, but only transiently. In rats, twice

doses. Plasma levels of F-15,063 decreased seven-fold 4 hours after oral administration, and 25-fold after 8 hours. Despite this, there was still a high

cannot be presumed that the i.p. LD50 will predict toxicity after oral administration. Microcystins are hepatotoxins. After acute exposure, severe liver

bioavailability of 36% on average, which is considered decent enough for oral administration and avoid the necessity of a more invasive route. The pharmacokinetics

healthy male volunteers found that rhein was better absorbed from oral administration of rhubarb than from a retention enema. Rhein (at an oral dose of

effectively treated mice with it they found the pharmacokinetics of oral administration in rats very negative. Brun et al. 2010 are of the opinion that Jansson's

cell study. A 2009 study involving 14 individuals indicated that oral administration of crocetin may decrease the effects of physical fatigue in healthy

the blood stream or orally, depending on the subject of interest. Oral administration is well suited to gastrointestinal tract scans, while intravascular

"Augemtnation of protective immune responses against viral infection by oral administration of schizophyllan". Mediators of Inflammation. 6 (4): 267–269. doi:10

100–250 mg. The first effects appear within 30–60 minutes following oral administration. MMDA produces euphoria and loving warmth, and attenuates feelings

and nervous systems. These effects are generally not reproduced by oral administration of the drug in test animals, and virtually no scientific reports

unidentified metabolites, with 86.6% excreted unchanged. Following oral administration, 59 to 87% of a dose of acecainide is excreted unchanged in the urine

no-observed-adverse-effect-level of acenaphthylene after repeated 28-day oral administration to both male and female rats was found to be 4 mg/kg/day. Nomenclature

likely to be absorbed, although some of them are only absorbed after oral administration if given as prodrugs. One advantage that small molecule drugs (SMDs)

brands. The wafers themselves are commonly used to facilitate the oral administration of various compounds or medications to rats in testing. Nilla's branding

is today marketed by Nestlé Health Science. In clinical studies, oral administration of proteolytic enzymes to healthy volunteers resulted in immunomodulatory

inhibitor in Pseudomonas aeruginosa. It is available for parenteral and oral administration.[citation needed] Another treatment option (typically used after

difficult to conclusively diagnose, but can be prevented by the oral administration of a magnet around the time that the animal reaches the age of one

study of mice with a defective Adenomatous polyposis coli gene, oral administration of zebularine to males had no effect on the overall methylation of

absorbed and has a limited "biological availability" so, following oral administration, it would be eliminated without being absorbed. The DNC therefore

an investigational small molecule antibiotic being evaluated for oral administration to treat Clostridioides difficile infection (CDI). In vitro, it is

distribution in cat studies was reported to be 918 ml/kg. Following an oral administration, the majority of the dose was metabolized within the first 72 hours

medical circles he became internationally famous for his research on oral administration of potassium iodide as a cure for mercury or lead poisoning. Melsens

platelet aggregation action.[citation needed] Calcium dobesilate after oral administration is well absorbed from the gastrointestinal tract. Maximum plasma

hemorrhagic and pathological conditions in both humans and animals via oral administration. In a limited number of human studies of small sample sizes, administration

glucose from carbon dioxide. This also leads to cell death. After oral administration of dinoseb tagged with 14C to rats and mice, it turned out that 40

of August 27, 2020, found the bioavailability of GS-441524 after oral administration of obdeldesivir (compound 15) in mice, rats, ferrets, dogs, and cynomolgus

Intravenous injection resulted in a half-life time of 2 hours, while oral administration resulted in a half-life time of 10 hours. Dermal administration lead

structure. Difloxacin is rapidly and almost completely absorbed after oral administration, and approximately 50% is bound to circulating plasma proteins. It

(1984). "Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man". International Journal of Clinical Pharmacology Research

the concentrations are always decreasing after the dose. But after oral administration, Cmax and tmax are dependent on the extent, and the rate of drug

Tajinder S; Matsuda, Fumiyo; Singh, Avtar K; Singh, Inderjit (2015). "Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates

KE (1984-07-01). "Pharmacokinetics of [4-14C] mofebutazone after oral administration in man". European Journal of Drug Metabolism and Pharmacokinetics

sufficient quantities. Ingested poisons are frequently treated by the oral administration of activated charcoal, which adsorbs the poison and flushes it from

century.[citation needed] Early use of emetine was in the form of oral administration of the extract of ipecac root, or ipecacuanha. This extract was originally

However, it is considered generally safe when applied this way. Oral administration of large doses of helenalin can cause gastroenteritis, muscle paralysis

precipitation in gastric fluid. Bevirimat was rapidly absorbed after oral administration, with detectable concentrations present in the plasma within 15 minutes

wall can all reduce the extent to which a drug is absorbed after oral administration. Absorption critically determines the compound's bioavailability

bioavailability of heptabarbital and heptabarbital sodium after oral administration to man". European Journal of Clinical Pharmacology. 9 (2–3): 169–78

direct sunlight, and away from sources of moisture. Tablets are for oral administration only. As a general rule, leukotriene receptor antagonists like zafirlukast

metabolized into desomorphine, among others, after parenteral and oral administration. Since 1936, desocodeine has been classified in the US as a Schedule

Bonacorsi SJ, et al. (June 2006). "Metabolism of [14C]gemopatrilat after oral administration to rats, dogs, and humans". Drug Metabolism and Disposition. 34 (6):

a study reported Lacticaseibacillus rhamnosus GG LTA (LGG-LTA) oral administration reduces UVB-induced immunosuppression and skin tumor development

geometry and linear algebra Per os or peroral, meaning "by mouth", i.e. oral administration of a medication Po (clothing), a traditional Korean overcoat Po (food)

following oral administration, suggesting minimal concern about untoward activation of TRPV1 receptors in other parts of the body. Single dose oral administration

isobuzole) is an oral antidiabetic drug, it is taken once daily by oral administration and it is water soluble to become pharmaceutically active within

tract allergies stimulated by PM2.5. For allergic rhinitis (AR), oral administration of Lactobacillus paracasei (all stored at 4°C before consumption)

modulator AC-262536 in vitro and in urine, plasma and hair following oral administration". Drug Testing and Analysis. 13 (2): 369–385. doi:10.1002/dta.2932

pharmacokinetics of fluocortolone and prednisolone after intravenous and oral administration". International Journal of Clinical Pharmacology, Therapy, and Toxicology

Placebo-controlled Study Investigating the Effects of Moxaverine on Ocular Blood Flow After Oral Administration in Healthy Subjects" at ClinicalTrials.gov v t e

more clinical data would be needed. Ivax acquired the rights for oral administration of cladribine to treat multiple sclerosis from Scripps in 2000, and

the Formation of Glycogen in the Organism of the White Rat after Oral Administration of d-Xylose". Journal of Biological Chemistry. 98 (1): 133–140. doi:10

Leaf, Alexander; Schwartz, William B.; Relman, Arnold S. (1954). "Oral Administration of a Potent Carbonic Anhydrase Inhibitor (Diamox)". New England Journal

corticosteroids very close but not into the eye). In resistant cases oral administration of corticosteroids, immunosuppressive drugs, and laser or cryotherapy

Cerón, J. J; Tomás-Barberán, F. A; Espín, J. C (2003). "Repeated oral administration of high doses of the pomegranate ellagitannin punicalagin to rats

levels of proglumetacin and its metabolites after intravenous or oral administration in the dog". Arzneimittel-Forschung. 37 (6): 698–702. PMID 3663267

with ketamine. In rats, oral administration of dextromethorphan did not cause vacuolization in laboratory tests. Oral administration of dextromethorphan repeatedly

National Center for Complementary and Integrative Health reported that oral administration of grape seed extract (dose and frequency unreported) was well tolerated

and relative bioavailability of cyclobarbital calcium in man after oral administration". European Journal of Clinical Pharmacology. 09 (5–6): 443–50. doi:10

action of glucagon, thus reducing fasting glucose levels. After oral administration of 50 mg of buformin to volunteers, almost 90% of the applied quantity

rats' brains when administered at doses of 75 mg/(kg ip). However, oral administration of dextromethorphan hydrobromide (DXM HBr) to female rats in single

Rarely occurs, but may cause nausea and vomiting associated with oral administration. It may also cause skin irritation.[citation needed] The FDA lists

known as BMS-582664 is an investigational, anti-tumorigenic drug for oral administration. The drug is being developed by Bristol-Myers Squibb for the treatment

Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract. Fuquan Xu, Huashi Guan, Guoqiang

cytokine and pro-inflammatory mediators. In rats with arthritis, oral administration of geniposide (30, 60, and 120 mg/kg) shows a decrease in T helper

administered intravenously is less than 5 minutes and within 30 minutes of oral administration (immediate release). While other opioids in its class, such as codeine

Randomized, Placebo-Controlled Trial to Assess the Safety and Efficacy of Oral Administration of EcoActive on Intestinal Adherent Invasive Escherichia Coli (AIEC)

concentrations of glucosamine in the synovial fluid and plasma after oral administration of glucosamine sulfate to both healthy volunteers and people with

Evaluation of an Oak-Flavored Milk Powder Containing Ellagitannins upon Oral Administration in the Rat". Journal of Agricultural and Food Chemistry. 56 (8):

1992). "Plasma and urinary concentrations of methamphetamine after oral administration of famprofazone to man". Xenobiotica; the Fate of Foreign Compounds

catechol-O-methyltransferase. The plasma half-life measured after oral administration is about two hours. Fischer J, Ganellin CR (2006). Analogue-based

solution for the treatment of fungal skin infections.[citation needed] Oral administration of fenticonazole in rats has been reported to produce prolonged gestation

Skorobohach BJ, Ward DA, Hendrix DV (February 2003). "Effects of oral administration of methazolamide on intraocular pressure and aqueous humor flow rate

stomach, leading to extensive degradation and loss of the drug after oral administration. In addition, intestinal efflux (secretory) transport can pump the

Arbat A, Gonzalez-Bulnes A, Pérez-Villalobos N, Canals I (2021). "Oral administration of sodium tungstate to a swine model improves embryo implantation

could not find toxicity in rodents for C60 and C70 mixtures after oral administration of a dose of 2 g/kg body weight and did not observe evidence of genotoxic

deaths. Abbott withdrew the drug from sale in June 1992. Following oral administration the compound is well absorbed from the gastrointestinal tract. The

metabolite, norcocaine, to cocaine's effects after intravenous and oral administration in rats: pharmacodynamics". Psychopharmacology. 153 (3): 341–52.

effect of collagen derivates on the ulcerative lesions caused by oral administration of ethanol". J Med Food. 10 (1): 154–8. doi:10.1089/jmf.2006.262

another procedure, the solution is usually taken orally, unless oral administration is contraindicated. Orally, the solution may be taken in a wide variety

Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract. Fuquan Xu, Huashi Guan, Guoqiang

is not known whether ebastine passes into the breast milk. After oral administration, ebastine undergoes extensive first-pass metabolism by hepatic cytochrome

carvedilol-loaded solid lipid nanoparticle for lymphatic absorption via oral administration". Pharmaceutical Development and Technology. 19 (4): 475–485. doi:10

prodrug is converted to the active metabolite spiraprilat following oral administration. Unlike other members of the group, it is eliminated both by renal

pharmacokinetics of CoQ10. The plasma peak can be observed 6–8 hours after oral administration when taken as a pharmacological substance. In some studies, a second

the chemotherapeutic agent, although some authors have argued that oral administration may be preferred. The concomitant administration of a NK1 receptor

tolerated. The observed systemic concentration of the drug following oral administration of 400 mg (0.01 ounces) gatifloxacin is approximately 800 times higher

Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract. Fuquan Xu, Huashi Guan, Guoqiang

effects of Ca antagonists darodipine and nimodipine after single-dose oral administration to healthy volunteers". Neuropsychobiology. 40 (3): 158–70. doi:10

induced by alcohol. Recordings of local field potentials indicate that oral administration of α5IA increases the amplitude of sharp wave ripples which are implicated

Stefan G.; Murphey-Corb, Michael; Parniak, Michael A. (2015). "Oral Administration of the Nucleoside EFdA (4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine) Provides

dextrose can be infused intravenously to raise the blood glucose. Oral administration of glucose can worsen the outcome, as more insulin is eventually

contact dermatitis. When used as a pharmaceutical excipient, after oral administration its bioavailability is about 0.34, due to a substantial first-pass

its low solubility and permeability has posed major hurdles for oral administration given its low bioavailability. In the past it had been used for fungal

maximum drug concentration in plasma) occurs 1 to 4 hours after oral administration. The mean serum half-life of sulfamethoxazole is 10 hours. However

Vulimiri; Matthew F.Starost; Melissa J.Reed; John DiGiovanni (2002). "Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation

metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers". The Journal of Clinical Pharmacology. 43

seven alkaloids and two flavonoids from rat plasma by HPLC–DAD after oral administration of Wuzhuyu decoction". Journal of Asian Natural Products Research

and/or chicken eggs yolks are used predominantly today. Long-term oral administration of colostrum-derived transfer factors has been shown to be safe.

dehydroepiandrosterone and its metabolites after long-term daily oral administration to healthy young men". Fertility and Sterility. 81 (3): 595–604.

manufacturer is a racemic mixture of R(+) and S(-) enantiomers. Following oral administration zileuton is rapidly absorbed with a mean time to peak blood serum

both intravenous (iv) and extravascular (non-intravenous, i.e., oral) administration. The absolute bioavailability is the dose-corrected area under curve

MD, Blackwell BN (August 1980). "Liver tumors induced in rats by oral administration of the antihistaminic methapyrilene hydrochloride". Science. 209

of mild to moderate Alzheimer's disease. Axona is formulated for oral administration and is sold by prescription. The largest ingredient in Axona is caprylic

(2): CD005117. doi:10.1002/14651858.CD005117.pub3. PMC 10712695. PMID 24515444. "Diacerein-containing medicines for oral administration". 2018-09-17.

and liver damage when administered in extremely high dosages. On oral administration, it produces diarrhea; intestinal bleeding may occur at higher doses

lactate contains 13% elemental calcium. In the early 20th century, oral administration of calcium lactate dissolved in water (but not in milk or tablets)

T; Ogawa, Y; Fukumitsu, H; Nomoto, H; Furukawa, S (Apr 2005). "Oral administration of royal jelly facilitates mRNA expression of glial cell line-derived

Rajfer J, Gonzalez-Cadavid NF (September 1997). "Effects of long-term oral administration of L-arginine on the rat erectile response". The Journal of Urology

acutely toxic, PAP was toxic only after injection, but not after oral administration, and OPAP was toxic only after injection of high doses. Therefore

properties, it also has some barbiturate-like properties. After oral administration, zopiclone is rapidly absorbed, with a bioavailability around 75–80%

Ba C, Broussy A, Romanet C, Dyhrfjeld-Johnsen J (October 2017). "Oral Administration of Clinical Stage Drug Candidate SENS-401 Effectively Reduces Cisplatin-induced

"Bilateral acute angle closure glaucoma in a 50 year old female after oral administration of flavoxate". British Journal of Clinical Pharmacology. 66 (5):

Bioavailability of tamsulosin and terazosin is around 90% during oral administration in fasting state. Food can have effect on absorption for tamsulosin

the fasting insulin test. A glucose tolerance test requires IV or oral administration of a sugar. Multiple blood draws are then performed to measure blood

(1991). "Dose-dependent pharmacokinetics of benzoic acid following oral administration of sodium benzoate to humans". Eur. J. Clin. Pharmacol. 41 (4): 363–8

(1991). "Dose-dependent pharmacokinetics of benzoic acid following oral administration of sodium benzoate to humans". Eur. J. Clin. Pharmacol. 41 (4): 363–8

cloxacillin, dicloxacillin and flucloxacillin are preferred for oral administration due to better bioavailability. Use in children <8 years only for

localized pain, which most of the time can be alleviated sufficiently by oral administration of mild analgesics such as ibuprofen, codeine or acetaminophen (paracetamol)

in an AUC0-24 value of 2.9 μg*h/mL and a Cmax value of 7.5 μg/mL. Oral administration resulted in an AUC0-24 value of 7.2 μg*h/mL and a Cmax value of 4

intramuscularly. Some are used in topical preparations for wounds. Oral administration can be used for gut decontamination (e.g., in hepatic encephalopathy)

a known hypersensitivity to the product, or to other macrolides. Oral administration can result in diarrhoea and gastrointestinal disturbance. This is

Tjhin, Vindy; Inagawa, Hiroyuki; Soma, Gen-Ichiro (January 2023). "Oral Administration of Lipopolysaccharide Enhances Insulin Signaling-Related Factors

PMID 20072638. Trier K, Cui D, Ribel-Madsen S, Guggenheim J (August 2022). "Oral administration of caffeine metabolite 7-methylxanthine is associated with slowed

impairment on the pharmacokinetics of azimilide following single dose oral administration". British Journal of Clinical Pharmacology. 54 (5): 449–52. doi:10

PMID 11888556. S2CID 34925312. Perez-García G, Meneses A (July 2005). "Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves

"Excretion of MBDB and BDB in urine, saliva, and sweat following single oral administration". Journal of Analytical Toxicology. 21 (7): 570–5. doi:10.1093/jat/21

and Alzheimer's disease. Perez-García G, Meneses A (July 2005). "Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves

"Quantitative analysis of nine coumarins in rat urine and bile after oral administration of Radix Glehniae extract by high-performance liquid chromatography-electrospray

Study to Evaluate the Efficacy, Safety, and Tolerability of 12-Week Oral Administration of PF-00734200 Tablets to Subjects with Type 2 Diabetes Mellitus

Evaluate the Safety, Tolerability, and Pharmacokinetics Following Oral Administration in Healthy Volunteers". Clinical Pharmacokinetics. 57 (1): 87–102

formation of blood clots. The RUBY-1 phase II trial results show that oral administration of darexaban in combination with the standard dual antiplatelet therapy

comparisons of activity in vitro and antibacterial action of blood after oral administration". The New England Journal of Medicine. 257 (12): 536–47 concl. doi:10

and quantify histamine-associated symptoms and to analyze whether oral administration of the histamine-degrading enzyme DAO caused a reduction of symptoms"

carcinogenicity of nickel sulfate via inhalation. In a 2-year study with daily oral administration of nickel sulfate hexahydrate to F344 rats, no evidence for increased

extent than cephalothin. Because it is also poorly absorbed after oral administration the use of this drug for humans declined rapidly, especially since

Ziemniak (1986). "Analysis of epinine and its metabolites in man after oral administration of its pro-drug ibopamine using high-performance liquid chromatography

benefits are unclear. A number of other effects are attributed to oral administration of gintonin-enriched extract in rodents. Ginseng Ginsenoside Lysophosphatidic

gastrointestinal absorption rate (within a few minutes), and complete following oral administration of tablets or the liquid form. It quickly diffuses into the liver

(1986). "Pharmacokinetics of chlordesmethyldiazepam after single-dose oral administration in humans". European Journal of Drug Metabolism and Pharmacokinetics

disseminated intravascular coagulation, deep vein thrombosis. After oral administration, it reaches peak plasma concentrations within one and a half hours

— 3000 Ionic cyanide concentrations measured in the brains of Sprague-Dawley rats one hour after oral administration of an LD50 of various nitriles.

and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine". Journal of Toxicology

Binding ranges from 60 to 80%. Cinoxacin is rapidly absorbed after oral administration. The presence of food delays absorption but does not affect total

July 2020. Gibaud S, Attivi D (August 2012). "Microemulsions for oral administration and their therapeutic applications" (PDF). Expert Opinion on Drug

3-O-β-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin". Free Radical Biology and Medicine. 30 (11): 1274–1285

CR, Jiang XH (2007). "Pharmacokinetics of huperzine A following oral administration to human volunteers". European Journal of Drug Metabolism and Pharmacokinetics

The quinolone is also active against Gram-negative bacteria After oral administration enoxacin is rapidly and well absorbed from the gastrointestinal tract

should not be performed with less than 111 MBq. Thyroid blocking via oral administration of 120 mg potassium iodide is recommended to minimize unnecessary

activity, drug discrimination, and cocaine self-administration after oral administration". European Journal of Pharmacology. 553 (1–3): 149–56. doi:10.1016/j

Retrieved 2019-02-06. 12.3 Pharmacokinetics/ Absorption: Following oral administration, the systemic bioavailability of losartan is approximately 33%. Mean

(RTI-336) possessed an LD50 of 180 mg/kg after oral administration, compared with 49 mg/kg for RTI-177 (unpublished results, Howell

A2A receptor pathway. Nimesulide is absorbed rapidly following oral administration. Nimesulide undergoes extensive biotransformation, mainly to 4-hydroxynimesulide

Papich MG (November 2023). "Pharmacokinetics of pimobendan after oral administration to dogs with myxomatous mitral valve disease". Journal of Veterinary

"Pharmacokinetics of brotizolam in healthy subjects following intravenous and oral administration". British Journal of Clinical Pharmacology. 16 (Suppl 2): 285S –

high doses are used to achieve intoxication and or sedation. After oral administration of loprazolam, it takes about 3 hours and a half for serum concentration

desmethyl-diazepam are seen between 30 minutes and 2 hours after oral administration of clorazepate. Clorazepate is completely metabolised to desmethyl-diazepam

10 ng/mL) due to extensive binding by tissues and erythrocytes. Oral administration is less-favored due to variable absorption from the stomach mucosa

humans, the sedative effects of ACT-462206 began 45 minutes after oral administration, and dissipated within 8 hours - consistent with a favorable pharmacodynamic

"Pharmacokinetics of leucovorin calcium after intravenous, intramuscular, and oral administration". Clinical Pharmacy. 7 (1): 52–58. PMID 3257913. "Leucovorin" (PDF)

et al. (March 2007). "Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam

(1): 18–22. doi:10.1016/j.ejphar.2005.04.026. PMID 15916757. After oral administration of sarpogrelate to rats, the peak sarpogrelate concentration in the

efficacious, therapeutic effects are usually seen within an hour of oral administration. 3:1 mix of d-amp and l-amp. Dexamfetamine Dexedrine, Dexrostat Children

free acid, potassium, and benzathine phenoxymethylpenicillin after oral administration". Br Med J. 1 (5033): 1451–2. doi:10.1136/bmj.1.5033.1451. PMC 1973440

metabolites. After collecting blood from rats 10 and 30 minutes after oral administration, plasma and red blood cell fractions were analyzed in search for

tolerability of dotarizine in healthy subjects after single and multiple oral administration". Methods and Findings in Experimental and Clinical Pharmacology

Peak concentrations of dapsone are reached within 1 to 3 hours of oral administration and have a half-life of 21 to 44 hours; about 50% of administered

the laboratory. In United States practice, intravenous (IV) and oral administration are considered to be equally effective and safe if given within 8 hours

in exposed animals. Toxicity values are 301 mg/kg in rats (LD50, oral administration), 300 mg/kg in mice (LD50, intraperitoneal administration). This

commonly administered orally in its sodium salt form. 3–4 hours after oral administration butabarbital sodium reaches peak plama concentrations of 203 ug/mL

Eells, JT (2005). "Absorption and elimination of formate following oral administration of calcium formate in female human subjects". Drug Metabolism and

positive allosteric modulator. Eszopiclone is rapidly absorbed after oral administration, with serum levels peaking between .45 and 1.3 hours. The elimination

"The pharmacokinetics and pharmacodynamics of medifoxamine after oral administration in healthy elderly volunteers". Eur. J. Clin. Pharmacol. 46 (2):

carcinogenesis, and other experiments show carcinogenic effects. Oral administration of high doses of caffeic acid in rats has caused stomach papillomas

Kang, Bongjo; Jang, Yeounghwan; Shin, Taekyun (2015). "Effect of oral administration of Kudoa septempunctata genotype ST3 in adult BALB/c mice". Parasite

Okumura Y, Arai T, Teramoto T, Nishimura M, et al. (August 2009). "Oral administration of the thyrotropin-releasing hormone (TRH) analogue, taltireline

bioavailability, this is simply a ratio of the peak plasma drug levels after oral administration and the drug concentration after an IV administration(first pass

Mortalities observed. Rats Once a day orally 4 weeks 10 or 30 mg/kg/day in males and females Mortality observed at oral administration of 90 mg/kg/day.

to 22.9%. The maximum plasma concentration of morphine following oral administration of heroin was around twice as much as that of oral morphine. Injection

effect varying rapidly. The effects last for about 4–6 hours after oral administration. The Swedish Riksdag added 4-HO-MET to Schedule I ("substances, plant

models, oral administration of favipiravir twice per day of 100 mg/kg significantly reduced viral load in the blood and antigen load in the lungs. Oral administration

two parameters that define the fate of the active ingredient after oral administration and ultimately define its bioavailability. When drug permeability

effect disappears by the third year of follow up. Paradoxically, oral administration of corticosteroids in this situation may lead to more recurrent attacks

consumption of fermented milk products. Metchnikoff also suggested that "oral administration of cultures of fermentative bacteria would implant the beneficial

than remaining static[self-published source?] Topical rather than oral administration[self-published source?] The protocol also includes a follow-up program

"Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration". J. Vet. Pharmacol. Ther. 31 (5): 437–45. doi:10.1111/j.1365-2885

(including β-lactamase-producing strains. Oral bioavailability: following oral administration, cefditoren pivoxil is absorbed from the gastrointestinal tract and

3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice". The Journal of Pharmacology and Experimental Therapeutics

pastures after enclosure. Experimental infection has been produced with oral administration of infected insects and subcutaneous inoculation of N. risticii.

should lead to a decrease in bone resorption — it has been shown that oral administration of vitamin D does not linearly correlate to increased serum levels

subsequent in vivo tests reported no genotoxicity for high dosage oral administration. It is a protein kinase C inhibitor. Echinacoside Taskova, Rilka

in other benzodiazepines. Tetrazepam, is rapidly absorbed after oral administration, within 45 mins and reaches peak plasma levels in less than 2 hours

sulfachloropyridazine residue levels in feathers from broiler chickens after oral administration using liquid chromatography coupled to tandem mass spectrometry"

green tea extract catechins and their endocrinological effects of oral administration in rats". Food and Chemical Toxicology. 40 (7): 925–33. doi:10

capsules respectively. Cmax was reached between 1.8–4 hours after oral administration. The tablet and capsule formulations are bioequivalent. Setipiprant

pancreas. Gnetin C showed the best effect among these stilbenoids. Oral administration of the 50% ethanol extract of melinjo fruit at 100 mg/kg/day significantly

of an ethyl ester group. Moexipril is incompletely absorbed after oral administration, and its bioavailability is low. The long pharmacokinetic half-life

hydrochloride salt is available for intramuscular, intravenous, rectal and oral administration. The teprosylate is available in intravenous, intramuscular, and

50%. There was good blood brain barrier permeability in rats after oral administration of all but epoxide. Pharmacokinetic studies after oral and intravenous

supplement. Studies support the positive effects of the chronic oral administration of the supplement on the injury and inflammation induced by intense

the H2 receptor. The potency of burimamide was still too low for oral administration. And efforts on further improvement of the structure, based on the

dissolved or infused into a vegetable oil for use in preparing foods for oral administration. Efforts to isolate the active ingredient in cannabis were well documented

The percent fractional elimination of (S)-equol in urine after oral administration is high and in some adults can reach close to 100 percent. The percent

Method for Analysis of Three Flavonols in Rat Plasma and Urine after Oral Administration of Polygonum aviculare Extract". Chromatographia. 69 (11–12): 1251–1258

It is also used for the control of potato and tomato leafspots. Oral administration to rats and cats, the most common signs of toxicity were diarrhea

been determined as 755 mg/kg for intraperitoneal and 4 g/kg for oral administration. In the light of these results, compounds of scandium should be handled

Swayam; Handa, Rahul (2015). "Purple glove syndrome occurring after oral administration of phenytoin in therapeutic doses: Mechanism still a dilemma". The

significant increase in the reaction rate of the semustine drug. After oral administration and absorption from the gastrointestinal tract, semustine undergoes

formed by amidation of tolmetin by glycine. Most is absorbed on oral administration. It is concentrated in the gastric wall. Highest concentration is

(1999). "Comparison of neurotoxic effects and potential risks from oral administration or ingestion of tricresyl phosphate and jet engine oil containing

involve intravenous administration of dilute sodium bicarbonate, oral administration of magnesium hydroxide, and/or repeated removal of rumen fluids and

body weight. Deaths occurred within minutes to several days after oral administration. Resulting in WHO's consideration of triazofos as a highly hazardous

precursor, accounting for the benzodiazepine-like effects after oral administration. Multiple N-dealkylations lead to the removal of the dimethylaminomethyl

well-defined ulcerations of the lip without induration. It is the result of oral administration of drugs, and the condition resolves when the drugs are stopped.

corresponding to 12.5 g for a 100 kg adult. Treatment may involve oral administration of dilute calcium hydroxide or calcium chloride to prevent further

interferes in the hypothalamic–pituitary–adrenal axis, with chronic oral administration of this drug leading to markedly reduced baseline cortisol levels

characteristic pattern of brain injury. Iodomethane has an LD50 for oral administration to rats 76 mg/kg, and is rapidly converted in the liver to S-methylglutathione

(PUVA therapy). PUVA is a photochemotherapy that involves topical or oral administration of the photosensitizing drug psoralen followed by skin exposure to

Enterobacteriaceae. It is currently being formulated as for intravenous and oral administration.[citation needed] Staphylococcus aureus (both methicillin-resistant

profiles to smoked THC, with a bioavailability ranging from 10 to 35%. Oral administration has the lowest bioavailability of approximately 6%, variable absorption

NON-PLASTICISED POLY(VINYL CHLORIDE) FOR CONTAINERS FOR DRY DOSAGE FORMS FOR ORAL ADMINISTRATION". In order to be suitable for pharmaceutical blister packs, the PVC

in healthy man: kinetics of parent drug and metabolites following oral administration". British Journal of Clinical Pharmacology. 15 (4): 459–64. doi:10

not been shown to be removed by hemodialysis). Treatment involves oral administration of activated charcoal, which adsorbs strychnine within the digestive

disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca". Drug Testing and Analysis. 4 (7–8): 610–6. doi:10

indicate no to very little systemic absorption of PVP following oral administration. PVP added to iodine forms a complex called povidone-iodine that

riddelliine has a carcinogenic effect on rats and mice. In rats, oral administration of riddelliine led to an increase in hemangiosarcomas in the liver

by the renal process after parenteral administration, while after oral administration a more pronounced metabolic clearance (high first pass effect) is

membranes Pessary of Prostin cream, prostaglandin E2 Intravaginal or oral administration of misoprostol Cervical insertion of a 30-mL Foley catheter Rupturing

Retrieved 2023-10-31. Bouskela E, Donyo KA (May 1997). "Effects of oral administration of purified micronized flavonoid fraction on increased microvascular

log P = –0.8.[citation needed] Phenformin is well absorbed after oral administration. The major metabolic reaction is aromatic hydroxylation to form 4-hydroxyphenformin

yohimbine-induced stress response in bonnet macaques (Macaca radiata); chronic oral administration of eglumetad in those animals led to markedly reduced baseline cortisol

instance, Palmer-Jones (1947) reported an LD50 of 20 mg/kg of tutin via oral administration in rats. Administration via subcutaneous (SC) and intraperitoneal

bloodstream. He found a method of treatment in the form of intravenous or oral administration of alkaline fluids. After the war, he built up rheumatology as an

use in oral gene discovery. Delivering genes non-virally through oral administration holds great promise for enhancing the efficacy of DNA vaccination

psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60

interfere in the hypothalamic–pituitary–adrenal axis, with chronic oral administration of this drug leading to markedly reduced baseline cortisol levels

administered via oral or I.V. administration, but the problem with oral administration is that one experimental study shows there is only a 35–50% absorption

of 3,4-Methylenedioxymethamphetamine ("Ecstasy") in Baboons after Oral Administration: Comparison with Humans Reveals Marked Differences". *Journal of

Lock EA (1996). "Neuropathological changes in rat brain following oral administration of 2-chloropropionic acid". Neurotoxicology. 17 (2): 471–480. PMID 8856742

has been shown to be an effective tocolytic. By intravenous and oral administration it produces a dose-dependent decrease in oxytocin-induced uterine

Pharmacokinetic studies performed on humans and experimental animals after oral administration of chondroitin sulfate revealed that it can be absorbed orally. Chondroitin

Ajinomoto KK  Zarka, Martin Hani; Bridge, Wallace John (2017). "Oral administration of γ-glutamylcysteine increases intracellular glutathione levels

within Toxicity Category IV of the toxicity category rating for oral administration, it is practically non-toxic and also not an irritant when taken

"Pharmacokinetic study of a new benzyl-1 isoquinoline derivative (458 L) after oral administration in men". Thérapie. 45 (1): 7–11. PMID 1971461. v t e

Lin, Wen-Chuan. "Treatment of chronic liver injuries in mice by oral administration of ethanolic extract of the fruit of Hovenia dulcis. American Journal

maximum plasma concentration (Cmax) is reached one to two hours after oral administration. The Cmax and AUC (area under the plasma vs. time curve) is dose

has also been shown to have a potent-anabolic effect on bone. The oral administration of AHZ or zinc acexamate has the restorative effect on bone loss

and metabolites in plasma, saliva, and urine following repeated oral administration to human volunteers". Journal of Analytical Toxicology. 24 (7): 467–477

(mouse, i.p.) of the HCl salt of NMPEA is 203 mg/kg; the LD50 for oral administration to mice of the same salt is 685 mg/kg. Acute toxicity studies on

Parallel-Group Study. Nutrients, 2018. 10(8). Liu, Y.W., et al., Oral administration of heat-inactivated Lactobacillus plantarum K37 modulated airway

has also been shown to have a potent-anabolic effect on bone. The oral administration of AHZ or zinc acexamate has the restorative effect on bone loss

the body's ability to break down choline ester drugs is impaired. Oral administration of enzymes can be used to treat some functional enzyme deficiencies

biological role in humans. The element is very poorly absorbed after oral administration and when injected its elimination is very slow. Lanthanum carbonate

and metabolites in plasma, saliva, and urine following repeated oral administration to human volunteers". Journal of Analytical Toxicology. 24 (7): 467–477

L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers". Clinical and Investigative

estradiol for subcutaneous application and ethinylestradiol for oral administration. Sialic acids are found at all cell surfaces of vertebrates and some

placebo-controlled study on acceptability, safety and efficacy of oral administration of sacha inchi oil (Plukenetia volubilis L.) in adult human subjects"

Chrousos GP, McCann SM, Suomi SJ, Higley JD, Gold PW (May 2000). "Oral administration of a corticotropin-releasing hormone receptor antagonist significantly

Technology, and Endocrinology. "Excretion of Homogentisic Acid After Oral Administration of Phenylalanine to Alcaptonuric Subjects" (1938, with Moses M. Fröhlich

(June 2012). "The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene". Biomaterials. 33 (19): 4936–4946. doi:10.1016/j

included those resistant to old acaricides. It is approved for oral administration mixed with the drinking water and has a systemic mode of action,

Lodinová-Zádníková R, Cukrowska B, Tlaskalova-Hogenova H (July 2003). "Oral administration of probiotic Escherichia coli after birth reduces frequency of allergies

In rats the metabolic pathway (figure 3) has been examined after oral administration of 14C-labelled amitraz, which was found to be effectively metabolized

products are digested more slowly than occurs for aerosol products. Oral administration generally leads to two peaks of concentration, due to enterohepatic

models, oral administration of favipiravir twice per day of 100 mg/kg significantly reduced viral load in the blood and antigen load in the lungs. Oral administration

atropine and digoxin immune fabs (antibodies) and treatment may include oral administration of activated charcoal. Ovine polyclonal anti-digitoxin Fab fragment

vitamin D is a direct inhibitor for Th17 differentiation. In this way, oral administration of vitamin D3 was proposed to be a promising tool for the treatment

the dose conversion) could produce symptoms of toxicity, and that oral administration of most drugs typically requires more drug than parenteral administration

"Serum concentration and half-life of rifampicin after simultaneous oral administration of aminosalicylic acid or isoniazid". European Journal of Clinical

YW; Tang, NY; Liu, HJ; Huang, CY; Hsieh, CL (2012). "Effect of oral administration of Pheretima aspergillum (earthworm) in rats with cerebral infarction

Muizzuddin, Neelam; Benjamin, Rodney (2020-02-21). "Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves

Metzler J, Diedrich JP, Freudenstein J, Bode C, Bode JC (2002). "Oral administration of freshly expressed juice of Echinacea purpurea herbs fail to stimulate

delayed by the use of progesterone or progestins. For this purpose, oral administration of progesterone or progestin during cycle day 20 has been found to

Transformation, by the devotees, and decorate his altar throughout the day. Oral administration of high doses aqueous/methanolic extract from the aerial parts of

morning, darkness therapy in the hours before bedtime, and timed oral administration of the hormone melatonin. Chronotherapy has also been prescribed

of the disease. For most people with early localized infection, oral administration of doxycycline is widely recommended as the first choice, as it is

purpose. Meprobamate is available in 200- and 400-mg tablets for oral administration. It is also a component of the combination drug Equagesic (discontinued