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searching for Type II collagen 37 found (73 total)

Protein trimer (565 words) [view diff] case mismatch in snippet view article find links to article

A heterotrimer would be formed by three different macromolecules. Type II Collagen is an example of homotrimeric protein, while Type I collagen is an

Osteochondrodysplasia (2,783 words) [view diff] exact match in snippet view article find links to article

swollen, stiff and deformed joints. Type II collagen disorders are caused by variants in the COL2A1 gene. Type II collagen disorders can result in mild disease

Matrix metallopeptidase 13 (1,781 words) [view diff] exact match in snippet view article find links to article

extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III[citation needed]. It may be involved

Mark Povinelli (1,020 words) [view diff] exact match in snippet view article find links to article

congenita (SEDc), a skeletal dysplasia caused by a mutation in the COL2A1 (type II collagen) gene. His repertory encompasses drama, comedy, and fantasy. He has

Patrick Tam (biologist) (203 words) [view diff] exact match in snippet view article

1997 SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse, Elsevier, 1997 Depletion of definitive

Glucosamine (3,355 words) [view diff] no match in snippet view article find links to article

J; et al. (2012). "Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: Pain evaluation

MAF (gene) (1,273 words) [view diff] exact match in snippet view article

2002). "A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene". The Journal of Biological Chemistry. 277 (52): 50668–75. doi:10

Nasal chondrocytes (2,863 words) [view diff] exact match in snippet view article find links to article

the cartilage surface. The cartilage matrix is mainly composed of type II collagen (90-95%), although small amounts of type IX and XI collagen are also

Skeleton (3,608 words) [view diff] exact match in snippet view article find links to article

that in an extracellular matrix. This matrix is typically composed of Type II collagen fibers, proteoglycans, and water. There are many types of cartilage

Amanda Fosang (605 words) [view diff] exact match in snippet view article find links to article

the structure and function of the cartilage molecules, aggrecan and type II collagen, and the enzymes that destroy them in arthritic disease. She and her

Heat shock protein 47 (1,584 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum. These cells synthesize and secrete type I and type II collagen. The protein localizes to the endoplasmic reticulum lumen and binds

Czech dysplasia, metatarsal type (698 words) [view diff] exact match in snippet view article find links to article

Geert R. (December 2007). "Czech dysplasia metatarsal type: another type II collagen disorder". European Journal of Human Genetics. 15 (12): 1269–1275.

HLA-DRB1 (677 words) [view diff] exact match in snippet view article find links to article

(DRB1*0101), complexed with the immunodominant determinant of human type II collagen 2g9h: Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex

Calorad (1,032 words) [view diff] exact match in snippet view article find links to article

Trentham, David E. (1998). "Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial"

P-selectin (2,589 words) [view diff] exact match in snippet view article find links to article

α-granules. Platelet activation (through agonists such as thrombin, Type II collagen and ADP) results in "membrane flipping" where the platelet releases

David Newsome (749 words) [view diff] exact match in snippet view article find links to article

other diseases. Smith GN, Linsemmayer TF, Newsome DA, Synthesis of type II collagen in vitro by embryonic chick neural retina tissue. Proc Natl Acad Sci

SOX5 (773 words) [view diff] exact match in snippet view article find links to article

Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene". The EMBO Journal. 17 (19): 5718–33. doi:10.1093/emboj/17.19

Tendon (5,143 words) [view diff] exact match in snippet view article find links to article

play vital roles in tendon development and function. These include type II collagen in the cartilaginous zones, type III collagen in the reticulin fibres

SOX6 (1,178 words) [view diff] exact match in snippet view article find links to article

Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene". The EMBO Journal. 17 (19): 5718–5733. doi:10.1093/emboj/17.19

Alpha collagen (555 words) [view diff] exact match in snippet view article find links to article

PMID 21917992. Oesser, Steffen; Seifert, Jürgen (2003-02-25). "Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded

P4HA1 (883 words) [view diff] exact match in snippet view article find links to article

PMID 16837461. Grimmer C, Balbus N, Lang U, et al. (2006). "Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible

P4HA2 (804 words) [view diff] case mismatch in snippet view article find links to article

PMID 16344560. Grimmer C, Balbus N, Lang U, et al. (2006). "Regulation of Type II Collagen Synthesis during Osteoarthritis by Prolyl-4-Hydroxylases : Possible

Annexin A5 (1,645 words) [view diff] exact match in snippet view article find links to article

V) to type II and X collagen and to chondrocalcin (C-propeptide of type II collagen). Implications for anchoring function between matrix vesicles and matrix

Michael Dunn (actor) (2,719 words) [view diff] exact match in snippet view article

defect of cartilage production caused by a mutation in the COL2A1 (type II collagen) gene. This disorder, classified as a skeletal dysplasia, causes distorted

Fibronectin type II domain (811 words) [view diff] no match in snippet view article find links to article

(2): 337–47. doi:10.1016/j.str.2015.11.008. PMC 4744086. PMID 26724997. Fibronectin type-II collagen-binding domain[permanent dead link] in PROSITE v t e

Tetrapeptide (1,949 words) [view diff] exact match in snippet view article find links to article

extracellular matrix component including; fibronectin, type I collagen, type II collagen, laminin, and lens capsule basement membrane. By utilizing time-lapse

Chondroclast (340 words) [view diff] no match in snippet view article find links to article

Polynucleated chondroclasts (brown staining) attach to the cartilage scaffold (asterisks) and synthesize cathepsin K to degrade the type-II collagen network.

TMEM106C (830 words) [view diff] exact match in snippet view article find links to article

48362667 on chromosome 12. This gene is in between COL2A1, the human type II collagen gene, and VDR, the human Vitamin D Receptor gene. This protein is found

Halperin-Birk syndrome (1,460 words) [view diff] exact match in snippet view article find links to article

Craniofacial dysmorphology, defects in trafficking of ECM proteins including type II collagen Medaka Skeletal and facial development defects Mice Early embryonic

Osteopontin (8,347 words) [view diff] exact match in snippet view article find links to article

"Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice". Proceedings of the National Academy

LECT2 (3,085 words) [view diff] exact match in snippet view article find links to article

knockout method developed more severe osteoarthritis induced by anti-type II collagen antibodies and lipopolysaccharide. The effect was reversed by administering

PEPD (3,545 words) [view diff] exact match in snippet view article find links to article

III collagen is produced by fibroblasts, which is later replaced by type II collagen, then type I collagen. These changes indicate different stages of the

Gene therapy for osteoarthritis (5,434 words) [view diff] exact match in snippet view article find links to article

factor Smad, Sox-9, IkB Apoptosis Inhibitor Bcl-2 Extra cellular matrix molecule Type II collagen, COMP Free radical antagonist Super Oxide Dismutase

Stem cell lineage database (2,073 words) [view diff] exact match in snippet view article find links to article

months. Chondrogenic differentiation was evident in the development of type II collagen that is seen in articular cartilage. Lastly, osteogenic differentiation

Artificial cartilage (3,500 words) [view diff] exact match in snippet view article find links to article

polypeptide chains and offers shear and tensile properties to the cartilage. Type II collagen is the most common type of collagen present in cartilage though types

Leo van de Putte (1,636 words) [view diff] exact match in snippet view article find links to article

"Phagocytic lining cells determine local expression of inflammation in type II collagen-induced arthritis". Arthritis and Rheumatism. 39 (9): 1545–1555. doi:10

Network of Excellence for Functional Biomaterials (3,578 words) [view diff] exact match in snippet view article find links to article

E; Velasco-Bayon, D; Murphy, M; O'Halloran, D; Pandit, A (2010). "Type II collagen-hyaluronan hydrogel – a step towards a scaffold for intervertebral