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Longer titles found: Neurofilament light polypeptide (view)

searching for Neurofilament 66 found (370 total)

Cerebral atrophy (2,196 words) [view diff] exact match in snippet view article find links to article

of biomarkers, namely one called neurofilament light chain (NFL), in patients with Alzheimer's disease. Neurofilament light chain is a protein that is

Protein kinase N1 (1,759 words) [view diff] exact match in snippet view article find links to article

(April 1996). "PKN associates and phosphorylates the head-rod domain of neurofilament protein". J. Biol. Chem. 271 (16): 9816–22. doi:10.1074/jbc.271.16.9816

Edward Wild (neuroscientist) (2,434 words) [view diff] exact match in snippet view article

disease. Wild's research since 2017 has focused on the potential of neurofilament light and mutant huntingtin protein as biomarkers for Huntington's disease

Permanent cell (278 words) [view diff] exact match in snippet view article find links to article

antibody to MAP2 (green), Neurofilament NF-H (red) and DNA (blue). MAP2 is found in neuronal dendrites, while the neurofilament is found predominantly in

Unipolar brush cell (1,037 words) [view diff] exact match in snippet view article find links to article

PMID 20937306. Harris J, Moreno S, Shaw G, Mugnaini E (December 1993). "Unusual neurofilament composition in cerebellar unipolar brush neurons". Journal of Neurocytology

Tau (1,416 words) [view diff] exact match in snippet view article find links to article

PMID 9846894 – via EuropeMC. M, Sjögren; E, Englund (2004). "Negative neurofilament light and tau immunostaining in frontotemporal dementia". Dementia and

Gökhan Okan (1,360 words) [view diff] exact match in snippet view article find links to article

their findings that psoriasis patients had unusually high levels of neurofilament and Tau protein, which act as a skeleton in the nerve cells in these

MTMR2 (856 words) [view diff] exact match in snippet view article find links to article

AP, Bolino A (2003). "Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral

MTMR2 (856 words) [view diff] exact match in snippet view article find links to article

AP, Bolino A (2003). "Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral

KIAA1143 (1,184 words) [view diff] exact match in snippet view article find links to article

has a predicted function of cell structure/mobility by encoding heavy neurofilament subunits in neurons. Immunohistochemistry staining from Thermo Fisher

Royal jelly (2,250 words) [view diff] exact match in snippet view article find links to article

mRNA expression of glial cell line-derived neurotrophic factor and neurofilament H in the hippocampus of the adult mouse brain". Biosci. Biotechnol.

List of histologic stains that aid in diagnosis of cutaneous conditions (254 words) [view diff] exact match in snippet view article find links to article

Muscle-specific actin Glomus tumor Dermatofibroma Infantile myofibromatosis Neurofilament Neurofibroma Neuro-specific enolase Merkel cell carcinoma Non-aqueous

Autosomal dominant Charcot–Marie–Tooth disease type 2 with giant axons (558 words) [view diff] exact match in snippet view article find links to article

extremities, early-onset high foot arch, and swelling of the nerve axons with neurofilament accumulation. Additional findings include gait anomalies, muscle cramps

Guangyuyuan (712 words) [view diff] exact match in snippet view article find links to article

Yiyong; Guo, Liankui (2005). "Effect of Guilingji on expression of neurofilament protein in cerebral cortex and corpus striatum". Chinese Journal of

Hirano body (868 words) [view diff] exact match in snippet view article find links to article

Trojanowski, J. Q. (1989). "Analysis of epitopes shared by Hirano bodies and neurofilament proteins in normal and Alzheimer's disease hippocampus". Lab. Invest

Nerve tissue protein (1,063 words) [view diff] exact match in snippet view article find links to article

Peptide, Brain Nerve Growth Factors Neuroendocrine Secretory Protein 7B2 Neurofilament Proteins Neurogranin Neuronal Apoptosis-Inhibitory Protein Neuronal

Chromosome 22 (2,209 words) [view diff] exact match in snippet view article find links to article

21-q11.23 COMT catechol-O-methyltransferase gene 22q12.1-q13.1 NEFH neurofilament, heavy polypeptide 200kDa 22q12.1 CHEK2 CHK2 checkpoint homolog (S.

Corticobasal syndrome (774 words) [view diff] exact match in snippet view article find links to article

Alzheimer's disease Pick's disease with Pick bodies Lewy body dementias Neurofilament inclusion body disease Creutzfeldt–Jakob disease Frontotemporal degeneration

Diagnosis of multiple sclerosis (3,284 words) [view diff] exact match in snippet view article find links to article

of predicting RIS to CIS conversion based on oligoclonal bands and neurofilament light chain. Multiple sclerosis diagnosis can only be made when there

Biomarkers of multiple sclerosis (7,797 words) [view diff] exact match in snippet view article find links to article

Thanks to the courage of these volunteers, now we know that in PPMS, neurofilament light chain (NF-L) level, in CSF and serum, is a sensitive and specific

Daniel Carleton Gajdusek (1,764 words) [view diff] exact match in snippet view article find links to article

Carleton (1985). "Hypothesis: interference with axonal transport of neurofilament as a common pathogenetic mechanism in certain diseases of the central

GMP reductase (1,388 words) [view diff] exact match in snippet view article find links to article

Alzheimer's disease. This is because Alzheimer's disease is due to neurofilament tangles (NFT) forming inside neurons, and phosphorylation of tau is

Matthis Synofzik (2,124 words) [view diff] exact match in snippet view article find links to article

large longitudinal study demonstrated that serum neurofilament light and phosphorylated neurofilament heavy can stratify the presymptomatic phase of genetic

ALS (13,993 words) [view diff] exact match in snippet view article find links to article

towards a slowing of progression, as well as a significant reduction in neurofilament light chain, a putative ALS biomarker thought to indicate neuronal damage

Ki-67 (protein) (1,365 words) [view diff] exact match in snippet view article

during the DNA synthesis. Immunofluorescent antibody staining against neurofilament (green) and Ki-67 (red) in a mouse embryo 12.5 days after fertilization

András Perczel (716 words) [view diff] exact match in snippet view article find links to article

prize (2011) Phosphorylation loops in synthetic peptides of the human neurofilament protein middle-sized subunit (co-author, 1988) Convex constraint analysis

Frontotemporal dementia (5,723 words) [view diff] exact match in snippet view article find links to article

Shaw LM, et al. (May 2021). "ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration". Alzheimer's

Ki-67 (protein) (1,365 words) [view diff] exact match in snippet view article

during the DNA synthesis. Immunofluorescent antibody staining against neurofilament (green) and Ki-67 (red) in a mouse embryo 12.5 days after fertilization

NDEL1 (2,014 words) [view diff] exact match in snippet view article find links to article

protein-containing complex binding Cellular component cytoplasm cell body neurofilament cytoskeleton nuclear envelope synaptic vesicle spindle chromosome microtubule

TAR DNA-binding protein 43 (4,646 words) [view diff] exact match in snippet view article find links to article

neurons TDP-43 has also been shown in humans to be a low molecular weight neurofilament (hNFL) mRNA-binding protein. It has also shown to be a neuronal activity

Surrogate endpoint (1,681 words) [view diff] exact match in snippet view article find links to article

Lussier FZ, et al. (March 2023). "Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials"

Cocaine intoxication (4,206 words) [view diff] exact match in snippet view article find links to article

in heavy users. Finally, a loss of vesicular monoamine transporters, neurofilament proteins, and other morphological changes appear to indicate a long-term

Palisade (pathology) (1,781 words) [view diff] exact match in snippet view article

neuronal markers such as synaptophysin, neuronspecific enolase, and neurofilament protein. Some medulloblastomas may also display other forms of differentiation

Betty Ida Roots (412 words) [view diff] exact match in snippet view article find links to article

and behaviour. Neuroscience & Biobehavioral Reviews. 2000. B Roots. Neurofilament accumulation induced in synapses by leupeptin. Science. 1983. Patricia

TSC1 (2,369 words) [view diff] exact match in snippet view article find links to article

(November 2002). "The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton"

Antisense therapy (2,476 words) [view diff] exact match in snippet view article find links to article

In trials the drug was found to lower levels of an ALS biomarker, neurofilament light change, and in long-term trial extensions to slow disease. Under

Rho-associated protein kinase (2,170 words) [view diff] exact match in snippet view article find links to article

proteins: Vimentin, GFAP (glial fibrillaric acidic protein), NF-L (neurofilament L protein) F-actin binding proteins: Adducin, EF-1&alpha (elongation

DLGAP2 (939 words) [view diff] exact match in snippet view article find links to article

protein 90/ postsynaptic density-95-associated protein (SAPAP) with neurofilaments". Genes Cells. 5 (3): 203–10. doi:10.1046/j.1365-2443.2000.00318.x.

Microtubule-associated protein 2 (1,380 words) [view diff] exact match in snippet view article find links to article

Stetzkowski-Marden F, Pradel LA (April 1991). "Interaction domains of neurofilament light chain and brain spectrin". Biochem. J. 275 (Pt 2): 521–7. doi:10

Superior olivary complex (3,100 words) [view diff] exact match in snippet view article find links to article

the human superior olivary complex by calcium binding proteins and neurofilament H (SMI-32)". The Journal of Comparative Neurology. 456 (3): 292–303

Neuropilin 1 (1,812 words) [view diff] exact match in snippet view article find links to article

growth cone receptor complex plasma membrane axon soma early endosome neurofilament cytoplasmic vesicle extracellular space focal adhesion neuron projection

Neuropilin 1 (1,812 words) [view diff] exact match in snippet view article find links to article

growth cone receptor complex plasma membrane axon soma early endosome neurofilament cytoplasmic vesicle extracellular space focal adhesion neuron projection

Superficial siderosis (1,562 words) [view diff] exact match in snippet view article find links to article

concentrations, and elevated levels of the proteins Tau, amyloid beta (Aβ42), neurofilament light chain (NFL), and glial fibrillary acidic protein (GFAP), but the

Radixin (1,146 words) [view diff] exact match in snippet view article find links to article

Ramesh V (2003). "The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton"

McDonald criteria (2,179 words) [view diff] exact match in snippet view article find links to article

circulating microRNA Some blood tests have been proposed based in circulating neurofilament light chain (NFL), in RNA profiling or in the MRZ reaction. Another

Elizabeth Fisher (neuroscientist) (1,168 words) [view diff] exact match in snippet view article

intracellular inclusions that are positive for ubiquitin, SOD, CDK5, and neurofilament. Fisher and Tybulewicz have demonstrated that mouse models can be used

Low-density lipoprotein receptor adapter protein 1 (1,118 words) [view diff] exact match in snippet view article find links to article

plasma membrane cytoplasmic side of plasma membrane AP-2 adaptor complex neurofilament axon early endosome plasma membrane clathrin-coated vesicle membrane

Boxing (14,530 words) [view diff] exact match in snippet view article find links to article

of brain damage. The Gothenburg study analyzed temporary levels of neurofilament light in cerebral spinal fluid which they conclude is evidence of damage

SHANK2 (1,590 words) [view diff] exact match in snippet view article find links to article

postsynaptic membrane cell projection membrane postsynaptic density neurofilament photoreceptor inner segment growth cone plasma membrane dendritic spine

SOD1 (3,631 words) [view diff] exact match in snippet view article find links to article

substance anterograde axonal transport spermatogenesis response to ethanol neurofilament cytoskeleton organization heart contraction embryo implantation locomotory

Kathryn Mary Murphy (594 words) [view diff] exact match in snippet view article find links to article

M.; Livingstone, Margaret S. (1 June 2007). "Cytochrome Oxidase and Neurofilament Reactivity in Monocularly Deprived Human Primary Visual Cortex". Cerebral

Czech Brain Ageing Study (983 words) [view diff] exact match in snippet view article find links to article

expression, and proteins related to neuronal/synaptic function, such as neurofilament light protein, neurogranin and contactin-2. The CBAS team is well established

PIN1 (2,792 words) [view diff] exact match in snippet view article find links to article

Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins". Journal of Neuroscience. 29 (47): 14869–14880. doi:10.1523/JNEUROSCI

CXorf66 (1,689 words) [view diff] exact match in snippet view article find links to article

homolog Horse (Equus caallus) 94.2 XP_005614614.1 96% 8.00E-58 44% Neurofilament medium polypeptide Zebra finch (Taeniopygia guttata) 296 XP_002197538

GABRB2 (5,576 words) [view diff] exact match in snippet view article find links to article

"Genome-wide association study identifies two loci influencing plasma neurofilament light levels". BMC Medical Genomics. 11 (1): 47. doi:10.1186/s12920-018-0364-8

MTOR (12,661 words) [view diff] exact match in snippet view article find links to article

rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability". The Journal of Biological Chemistry. 284 (40): 27416–24

Hereditary diffuse leukoencephalopathy with spheroids (2,136 words) [view diff] exact match in snippet view article find links to article

immunohistochemistry for ubiquitin, amyloid precursor protein, and neurofilament to characterize axonal changes and myelin basic protein for myelin pathology

Concussions in American football (14,076 words) [view diff] exact match in snippet view article find links to article

tests; evidence is revealing no change in blood plasma tau and serum neurofilament light concentrations following sport related concussions. However these

Astroblastoma (2,960 words) [view diff] exact match in snippet view article find links to article

Neuron-specific enolase (NSE) positive, NSE negative, synaptophysin negative, neurofilament negative, TUJ1 positive, and nestin positive have been expressed in

Sports-related traumatic brain injury (5,558 words) [view diff] exact match in snippet view article find links to article

instability. After fighting, boxers show raised cerebrospinal fluid levels of neurofilament light chain and total tau then they did after three months with no boxing

Sarah Tabrizi (3,639 words) [view diff] exact match in snippet view article find links to article

functional impairment, yet there was evidence of elevated levels of neurofilament light protein, suggestive of very early neuronal damage, in those closest

David L. Nelson (2,388 words) [view diff] exact match in snippet view article find links to article

Robert Lazzarini, Nelson studied neuroscience and defined genes encoding neurofilament proteins. In 1986 he joined the C. Thomas Caskey laboratory at the Institute

Steven L. Small (2,350 words) [view diff] exact match in snippet view article find links to article

L. (2022). Salivary S100 calcium-binding protein beta (S100B) and neurofilament light (NfL) after acute exposure to repeated head impacts in collegiate

Stem cell marker (5,691 words) [view diff] exact match in snippet view article find links to article

Mouse orthologue of ARX MRP4 Msi-1 Musashi Musashi-1 Mutant BCRP nestin neurofilament microtubule-associated protein 2 neuron-glial antigen 2 (NG2) notch

Memory development (5,914 words) [view diff] exact match in snippet view article find links to article

chitinase-3-like protein 1 (YKL-40), fatty acid binding protein 3 (FABP3), and neurofilament light (NFL), and their findings suggest that tauopathy and FABP3 tended

Alzheimer's disease among East Asians (9,220 words) [view diff] exact match in snippet view article find links to article

cost-effective and less invasive. Plasma measurements of amyloid-β, neurofilament light chain (NfL), and phosphorylated tau (p-tau) can be used to diagnose