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searching for Homology directed repair 39 found (71 total)

alternate case: homology directed repair

Maria Jasin (924 words) [view diff] no match in snippet view article find links to article

Roger D.; Thompson, Larry H.; Jasin, Maria (1999). "XRCC3 promotes homology-directed repair of DNA damage in mammalian cells". Genes & Development. 13 (20):

Glabrousness (529 words) [view diff] no match in snippet view article find links to article

Marion; Mantegazza, Otho; Weber, Andreas P. M. (5 April 2018). "Homology-Directed Repair of a Defective Glabrous Gene in Arabidopsis With Cas9-Based Gene

Synthesis-dependent strand annealing (1,822 words) [view diff] no match in snippet view article find links to article

Synthesis-dependent strand annealing (SDSA) is a major mechanism of homology-directed repair of DNA double-strand breaks (DSBs). Although many of the features

XRCC3 (1,745 words) [view diff] no match in snippet view article find links to article

Pierce AJ, Johnson RD, Thompson LH, Jasin M (1999). "XRCC3 promotes homology-directed repair of DNA damage in mammalian cells". Genes Dev. 13 (20): 2633–2638

Trichome (2,951 words) [view diff] no match in snippet view article find links to article

Marion; Mantegazza, Otho; Weber, Andreas P. M. (5 April 2018). "Homology-Directed Repair of a Defective Glabrous Gene in Arabidopsis With Cas9-Based Gene

Downregulation and upregulation (2,016 words) [view diff] no match in snippet view article find links to article

Gottesman, Max E; Avvedimento, Enrico V (6 July 2007). "DNA Damage, Homology-Directed Repair, and DNA Methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

NOVA1 (843 words) [view diff] no match in snippet view article find links to article

N, Maricic T, Pääbo S (2023-07-20). "Efficient high-precision homology-directed repair-dependent genome editing by HDRobust". Nature Methods. 20 (9):

Enhancer of polycomb homolog 2 (drosophila) (516 words) [view diff] no match in snippet view article

PR (April 2010). "MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks". Journal of Cell Science. 123 (Pt 7): 1124–30

DNA methylation in cancer (3,792 words) [view diff] no match in snippet view article find links to article

C, Porcellini A, Angrisano T, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

NEIL1 (1,846 words) [view diff] no match in snippet view article find links to article

Chiariotti L, Gottesman ME, Avvedimento EV (Jul 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Joachim Lingner (1,064 words) [view diff] exact match in snippet view article find links to article

chromatin structure and telomere maintenance by telomerase and homology directed repair. Finally, they developed technologies to uncover the changes that

Chromosomal crossover (3,787 words) [view diff] exact match in snippet view article find links to article

of double-strand breaks (DSBs). DSBs are often repaired using homology directed repair, a process which involves invasion of a template strand by the

G2 phase (2,818 words) [view diff] no match in snippet view article find links to article

cell in G2 until the damage is repaired by mechanisms such as homology-directed repair (see above). Long-term maintenance of the G2 arrest is also mediated

Epigenetic clock (7,293 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Neoplasm (5,895 words) [view diff] no match in snippet view article find links to article

Chiariotti L, Gottesman ME, Avvedimento EV (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genet. 3 (7): e110. doi:10.1371/journal

Non-small-cell lung cancer (5,439 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

CpG site (5,478 words) [view diff] no match in snippet view article find links to article

C, Porcellini A, Angrisano T, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Epigenetics (18,274 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Regulation of transcription in cancer (2,390 words) [view diff] no match in snippet view article find links to article

C, Porcellini A, Angrisano T, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Zinc finger (4,882 words) [view diff] exact match in snippet view article find links to article

the genomic locus can be converted to a defined sequence via the homology directed repair pathway. An ongoing clinical trial is evaluating Zinc finger nucleases

RAD52 (3,093 words) [view diff] no match in snippet view article find links to article

Chiariotti L, Gottesman ME, Avvedimento EV (Jul 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Provirus silencing (1,273 words) [view diff] no match in snippet view article find links to article

demonstrated that targeted integration of a lentiviral payload using homology-directed repair can result in stable integration and expression. In this approach

Genome instability (4,560 words) [view diff] no match in snippet view article find links to article

Chiariotti, L; Gottesman, ME; Avvedimento, EV (2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genet. 3 (7): e110. doi:10.1371/journal

Glioma (6,991 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Protein inhibitor of activated STAT (3,257 words) [view diff] no match in snippet view article find links to article

Z, Zhang H, Ye Q, Jiao S, Xu X (October 2013). "PIAS3 promotes homology-directed repair and distal non-homologous end joining". Oncology Letters. 6 (4):

ATM serine/threonine kinase (5,695 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

DNA-PKcs (3,754 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Cancer epigenetics (12,533 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Evolution of the brain (7,812 words) [view diff] no match in snippet view article find links to article

Kowalewski J, et al. (September 2023). "Efficient high-precision homology-directed repair-dependent genome editing by HDRobust". Nature Methods. 20 (9):

Human genetic enhancement (10,225 words) [view diff] no match in snippet view article find links to article

specific CRISPR/Cas method. It can help with single-base exchanges, homology-directed repair, and non-homologous end joining. The primary application is targeted

Cancer (20,132 words) [view diff] no match in snippet view article find links to article

Morano A, Lee B, Di Pardo A, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Oncogenomics (7,684 words) [view diff] no match in snippet view article find links to article

C, Porcellini A, Angrisano T, et al. (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Surveyor nuclease assay (3,176 words) [view diff] no match in snippet view article find links to article

followed by repair through the non-homologous end-joining (NHEJ) or homology-directed repair (HDR) pathways. While HDR is expected to introduce a consistent

Jian-Kang Zhu (2,374 words) [view diff] no match in snippet view article find links to article

Arabidopsis. They have also developed an elegant tandem repeat-HDR (homology-directed repair) approach for efficient sequence insertion and replacement in rice

Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (1,801 words) [view diff] no match in snippet view article find links to article

Shin (2024-06-01). "Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice

Carcinogenesis (13,967 words) [view diff] no match in snippet view article find links to article

Chiariotti L, Gottesman ME, Avvedimento EV (July 2007). "DNA damage, homology-directed repair, and DNA methylation". PLOS Genetics. 3 (7): e110. doi:10.1371/journal

Human germline engineering (6,512 words) [view diff] no match in snippet view article find links to article

mutation in human embryos. The study claimed precise CRISPR/Cas9 and homology-directed repair response with high accuracy and precision. By modifying the cell

No-SCAR genome editing (5,650 words) [view diff] exact match in snippet view article find links to article

specific to the cleaved location as a template to rebuild using homology directed repair. This method is advantageous in that it allows multiple mutations

January–March 2021 in science (13,101 words) [view diff] no match in snippet view article find links to article

Tomislav; Pääbo, Svante (20 July 2023). "Efficient high-precision homology-directed repair-dependent genome editing by HDRobust". Nature Methods. 20 (9):