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searching for Hair cell 82 found (161 total)

alternate case: hair cell

Root hair (1,207 words) [view diff] exact match in snippet view article find links to article

by increasing root surface area to volume ratio which allows the root hair cell to take in more water. The large vacuole inside root hair cells makes

GPR156 (643 words) [view diff] exact match in snippet view article find links to article

protein family. In 2021, an article was reported that GPR156 modulates hair cell orientation in the cochlea. Also, it was proposed that GPR156 is related

Endothrix (82 words) [view diff] exact match in snippet view article find links to article

infections of the hair that invade the hair shaft and internalize into the hair cell. This is in contrast to exothrix (ectothrix), where a dermatophyte infection

Mir-96 microRNA (826 words) [view diff] exact match in snippet view article find links to article

in hair cells. Mice mutant for the latter three exhibit deafness and hair cell degeneration. Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B

Tip link (328 words) [view diff] exact match in snippet view article find links to article

transduction channels that allow potassium and calcium ions to enter the hair cell from the endolymph that bathes its apical end. When the hair cells are

Otolithic membrane (2,644 words) [view diff] exact match in snippet view article find links to article

utricle, while the saccular macula lies vertical in the saccule. Every hair cell in these sensory beds consist of 40-70 stereocilia and a kinocilium. The

Macula of saccule (332 words) [view diff] exact match in snippet view article find links to article

nearly vertical position. It is a 2mm by 3mm patch of hair cells. Each hair cell of the macula contains 40 to 70 stereocilia and one true cilia, called

CHRNA9 (754 words) [view diff] exact match in snippet view article find links to article

hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell function and is expressed in both the inner and outer hair cells (OHCs)

Vesicular glutamate transporter 3 (548 words) [view diff] exact match in snippet view article find links to article

transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice". Am. J. Hum. Genet. 83 (2): 278–92. doi:10.1016/j

Auditory neuropathy (1,261 words) [view diff] exact match in snippet view article find links to article

classic AN paradigm would include present OAEs indicating normal outer hair cell function, absent or abnormal ABR with presence of the cochlear microphonic

Peter Dallos (1,721 words) [view diff] exact match in snippet view article find links to article

that outer hair cell axial stiffness is voltage dependent [2.12] Discovery and elucidation of the properties of the unique outer hair cell motor protein

Deiters' cells (126 words) [view diff] exact match in snippet view article find links to article

In the mammalian cochlea, each outer hair cell stands on the soma of a cell of Deiters. What is not apparent in this diagram is that the phalangeal process

Calcium-dependent chloride channel (1,531 words) [view diff] exact match in snippet view article find links to article

subunits (see also family TC# 1.A.82). Mice lacking both channels lack hair cell mechanosensory potentials. There are 8 members of this family in humans

Stem-cell therapy (9,669 words) [view diff] no match in snippet view article find links to article

Stem-cell therapy uses stem cells to treat or prevent a disease or condition. As of 2024[update], the only FDA-approved therapy using stem cells is hematopoietic

Artificial lateral line (1,908 words) [view diff] exact match in snippet view article find links to article

flow and acoustic sensing. Some species (like arthropods) use a single hair cell for this function and other creatures like fish use a bundle of hair cells

Computational auditory scene analysis (1,985 words) [view diff] exact match in snippet view article find links to article

the hair cells include the Meddis hair cell model which pairs with the gammatone filter bank, by modeling the hair cell transduction. Based on the assumption

STS-65 (2,626 words) [view diff] exact match in snippet view article find links to article

with hair cell receptors and otoconia, detect linear acceleration of the head. When the head moves, the otoconia lag behind, bending the hair cell receptors

LOXHD1 (306 words) [view diff] exact match in snippet view article find links to article

to auditory defects, indicating that this gene is essential for normal hair cell function. Screening of human families segregating deafness identified

Choline transporter-like protein 4 (583 words) [view diff] exact match in snippet view article find links to article

cell growth choline transport thiamine pyrophosphate transmembrane transport otolith formation neuromast hair cell development Sources:Amigo / QuickGO

Achaete-scute complex (433 words) [view diff] exact match in snippet view article find links to article

microchaetae) on the back of the adult fly. Achaete functions to specify sensory hair cell fate. It functions downstream of other genes, including hairy and extramacrochaete

Mongolian gerbil (3,792 words) [view diff] exact match in snippet view article find links to article

2015). "Aminoglycoside ototoxicity and hair cell ablation in the adult gerbil: A simple model to study hair cell loss and regeneration". Hearing Research

Espin (protein) (759 words) [view diff] exact match in snippet view article

a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins". Cell. 102 (3): 377–85. doi:10.1016/S0092-8674(00)00042-8

Endocochlear potential (227 words) [view diff] exact match in snippet view article find links to article

This is known as the Battery Hypothesis. The receptor potential for each hair cell causes a release of neurotransmitters at its basal pole, which elicits

Transpiration stream (470 words) [view diff] exact match in snippet view article find links to article

cytoplasm of the root hair cells. As the cell's surface membrane of the root hair cell is semi-permeable, osmosis can take place; and water passes from the soil

STRC (721 words) [view diff] exact match in snippet view article find links to article

Houdon C, Weil D, et al. (February 2011). "Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane". The Journal

Vestibular evoked myogenic potential (1,313 words) [view diff] exact match in snippet view article find links to article

cells from the saccule. Each hair cell has about 70 stereocilia (short rod-like hair cells) and one kinocilium (long hair cell). Bickford et al. (1964) and

Liam Dolan (936 words) [view diff] exact match in snippet view article find links to article

Arabidopsis root and discovered the molecular genetic mechanism governing root hair cell differentiation. He demonstrated that this mechanism is ancient and was

Automatic gain control (1,772 words) [view diff] no match in snippet view article find links to article

Feb 1939. D. O. Kim (1984). "Functional roles of the inner-and outer-hair-cell subsystems in the cochlea and brainstem". In C. I. Berlin (ed.). Hearing

Lisa L. Cunningham (450 words) [view diff] exact match in snippet view article find links to article

(HSP)-mediated protection against ototoxic drug-induced hearing loss and hair cell death. This work was funded by a Research Project Grant (R01) from the

Trichocyte (algae) (166 words) [view diff] exact match in snippet view article

[1] Judson, B.L.; Pueschel, C.M. (2002), "Ultrastructure of trichocyte(hair cell) complexes in Jania adhaerens(Corallinales, Rhodophyta)", Phycologia,

Animal echolocation (9,683 words) [view diff] exact match in snippet view article find links to article

sensitivity: Tmc1 is associated with hair cell development and high-frequency hearing, and Pjvk with hair cell function. Molecular evolution of Tmc1

Neomycin (2,085 words) [view diff] exact match in snippet view article find links to article

cochlea, which is found in the inner ear. Hearing loss is caused by ear hair cell death, which occurs in response to treatment with neomycin. Patients with

Equal-loudness contour (2,214 words) [view diff] no match in snippet view article find links to article

in our inner ear analyzes sounds in terms of spectral content, each "hair-cell" responding to a narrow band of frequencies known as a critical band.

Fimbrin (689 words) [view diff] exact match in snippet view article find links to article

structures in different cell types, including intestinal microvilli, hair cell stereocilia and fibroblast filopodia. It is usually associated with polarized

Cyclodextrin (2,498 words) [view diff] exact match in snippet view article find links to article

Thomas PV, Benson J, Kanicki A, Kabara L, et al. (2012). "Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin"

Volley theory (2,231 words) [view diff] exact match in snippet view article find links to article

Later, Friedrich Voltolini added on by proposing that every auditory hair cell is stimulated by any sound. Correspondingly, William Rutherford provided

TMC2 (516 words) [view diff] no match in snippet view article find links to article

deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function". Nat Genet. 30 (3): 277–84. doi:10.1038/ng842. PMID 11850618

PITX2 (3,419 words) [view diff] exact match in snippet view article find links to article

vasculogenesis regulation of cell population proliferation myoblast fusion hair cell differentiation spleen development regulation of transcription, DNA-templated

ERCC2 (1,846 words) [view diff] exact match in snippet view article find links to article

polymerase I promoter transcription elongation from RNA polymerase II promoter hair cell differentiation ageing extracellular matrix organization in utero embryonic

JAG2 (1,018 words) [view diff] exact match in snippet view article find links to article

Weinmaster G, Gridley T, Kelley MW (1999). "Notch signalling pathway mediates hair cell development in mammalian cochlea". Nat. Genet. 21 (3): 289–92. doi:10

XPB (2,065 words) [view diff] exact match in snippet view article find links to article

process positive regulation of apoptotic process protein phosphorylation hair cell differentiation response to oxidative stress UV protection cellular response

Cav1.3 (3,339 words) [view diff] exact match in snippet view article find links to article

integral component of membrane membrane plasma membrane Z discdkac cochlear hair cell ribbon synapse integral component of presynaptic active zone membrane

Glutamate transporter (2,828 words) [view diff] exact match in snippet view article find links to article

transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice". American Journal of Human Genetics. 83 (2):

Mechanotransduction (3,046 words) [view diff] exact match in snippet view article find links to article

journal requires |journal= (help) Fettiplace, Robert (September 12, 2017). "Hair cell transduction, tuning and synaptic transmission in the mammalian cochlea"

LEKTI (1,230 words) [view diff] exact match in snippet view article find links to article

negative regulation of peptidase activity epithelial cell differentiation hair cell differentiation extracellular matrix organization negative regulation

Special senses (1,924 words) [view diff] exact match in snippet view article find links to article

(2011). "Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction". Nat Commun. 2: 523. Bibcode:2011NatCo...2..523P

Surface wave detection by animals (3,655 words) [view diff] no match in snippet view article find links to article

and supratemporal/post-orbital (III). Each neuromast is a cluster of hair-cell bundles arranged in a line and numbering in the 10s to 100s. Each bundle

Hyperacusis (4,443 words) [view diff] exact match in snippet view article find links to article

of these type II afferent fibers may be caused by a flood of ATP after hair cell damage. Now sensitized, they react to the small amount of ATP released

CDH23 (1,364 words) [view diff] exact match in snippet view article find links to article

cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle". The EMBO Journal. 21 (24): 6689–99. doi:10.1093/emboj/cdf689

Dizocilpine (3,400 words) [view diff] exact match in snippet view article find links to article

polyamines at NMDA receptors and produce excitotoxic damage, leading to hair cell loss. Antagonizing NMDA receptors to reduce the excitotoxicity would prevent

Signal transduction (7,609 words) [view diff] exact match in snippet view article find links to article

(September 1975). "Davis-1961 revisited. Signal transmission in the cochlear hair cell-nerve junction". Archives of Otolaryngology. 101 (9): 528–35. doi:10.1001/archotol

Goldman–Hodgkin–Katz flux equation (1,410 words) [view diff] case mismatch in snippet view article find links to article

Flax, Matt R. and Holmes, W.Harvey (2008). Goldman-Hodgkin-Katz Cochlear Hair Cell Models – a Foundation for Nonlinear Cochlear Mechanics, Conference proceedings:

Usher syndrome (3,528 words) [view diff] no match in snippet view article find links to article

"Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction". Proceedings of the National Academy of

Mitogen-activated protein kinase (5,492 words) [view diff] exact match in snippet view article find links to article

protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss". The Journal of Neuroscience. 23 (24): 8596–607

Synaptopathy (752 words) [view diff] exact match in snippet view article find links to article

Jean-Luc (May 2007). "Physiology, pharmacology and plasticity at the inner hair cell synaptic complex". Hearing Research. 227 (1–2): 19–27. doi:10.1016/j.heares

Transporter Classification Database (5,159 words) [view diff] case mismatch in snippet view article find links to article

Family 1.A.81 The Low Affinity Ca2+ Channel (LACC) Family 1.A.82 The Hair Cell Mechanotransduction Channel (HCMC) Family 1.A.83 The SV40 Virus Viroporin

Spatial hearing loss (3,037 words) [view diff] exact match in snippet view article find links to article

Wong J, Rieger B, Polcz V, Smith D; Interaural attention modulates outer hair cell function; Eur J Neurosci. 40(12), 2014 Glyde H, Hickson L, Cameron S,

USH2A (1,111 words) [view diff] exact match in snippet view article find links to article

Biological process response to stimulus establishment of protein localization hair cell differentiation sensory perception of light stimulus hearing inner ear

Pure-tone audiometry (2,219 words) [view diff] exact match in snippet view article find links to article

wide range of topics covered including sound, cochlea, Organ of Corti, hair cell pathology and audiometry. Audiology Resources. This site provides useful

Examples of in vivo transdifferentiation by lineage-instructive approach (399 words) [view diff] exact match in snippet view article find links to article

Swiderski, D. L.; Dolan, D. F.; Brough, D. E.; Raphael, Y. (2005). "Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals"

EPS8 (1,480 words) [view diff] exact match in snippet view article find links to article

Petit C (2014). "EPS8, encoding an actin-binding protein of cochlear hair cell stereocilia, is a new causal gene for autosomal recessive profound deafness"

Ageing (11,527 words) [view diff] exact match in snippet view article find links to article

2016. Rubel EW, Furrer SA, Stone JS (March 2013). "A brief history of hair cell regeneration research and speculations on the future". Hearing Research

Regeneration (biology) (9,307 words) [view diff] exact match in snippet view article

S2CID 39410595. Cotanche DA, Lee KH, Stone JS, Picard DA (January 1994). "Hair cell regeneration in the bird cochlea following noise damage or ototoxic drug

Sex-chromosome dosage compensation (7,546 words) [view diff] exact match in snippet view article find links to article

because only they randomly inactivate one X chromosome in every somatic hair cell. Thus, presuming that hair color determining genes are X-linked, it makes

RIPOR2 (546 words) [view diff] exact match in snippet view article find links to article

Lu Z, Tekin M (July 2014). "FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing". Proceedings of the National Academy

ARHGEF6 (1,629 words) [view diff] case mismatch in snippet view article find links to article

Xiong W, Gao X, Xu Z, Chai R (October 2018). "Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice". Frontiers in Molecular

Jonathon Howard (1,496 words) [view diff] exact match in snippet view article find links to article

of mechanoelectrical transduction channels in the Bullfrog's saccular hair cell". Neuron. 1 (3): 189–199. doi:10.1016/0896-6273(88)90139-0. PMID 2483095

Let-7 microRNA precursor (8,221 words) [view diff] exact match in snippet view article find links to article

members as potential regulators of dedifferentiation in lens and inner ear hair cell regeneration of the adult newt". Biochemical and Biophysical Research

Sound level meter (6,302 words) [view diff] exact match in snippet view article find links to article

permanent shifts in auditory threshold, the latter being correlated to hair cell function. The AHAAH's claimed improvements in accuracy are often attributed

Catenin beta-1 (12,347 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway nervous system development forebrain development hair cell differentiation negative regulation of transcription by RNA polymerase

Cells at Work! (7,377 words) [view diff] exact match in snippet view article find links to article

had also killed several Neutrophils and turned them into pus. A young hair cell almost gives in to despair and says they are only one hair and unimportant

Ferlins (3,105 words) [view diff] exact match in snippet view article find links to article

plays a role in exocytosis of synaptic vesicles at the auditory inner hair cell ribbon synapse. In adult fruit flies, a ferlin member called misfire is

John Oghalai (1,539 words) [view diff] exact match in snippet view article find links to article

WE (2000). "Voltage- and tension-dependent lipid mobility in the outer hair cell plasma membrane". Science. 287 (5453): 658–61. doi:10.1126/science.287

Gene therapy for epilepsy (2,918 words) [view diff] exact match in snippet view article find links to article

seizures. Conducted studies confirm these findings of preventing hilar hair cell loss, decreasing the number and duration of induced seizures, increasing

Cochlear hydrops (2,051 words) [view diff] exact match in snippet view article find links to article

affected ear(s). A study looking at spiral ganglion cell counts compared to hair cell counts in the inner ear of patients who had Meniere's disease found that

Calcium binding protein 2 (607 words) [view diff] case mismatch in snippet view article find links to article

Tobias; Pangrsic, Tina (2021-08-19). "Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model". Frontiers

Hernan Lopez-Schier (499 words) [view diff] no match in snippet view article find links to article

optogenetics to repair damaged neurons, and the first to identify the source of hair-cell regeneration. As of 2023, he has an H-index of 29. "Hernán López-Schier"

Major facilitator superfamily (5,028 words) [view diff] exact match in snippet view article find links to article

transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice". American Journal of Human Genetics. 83 (2):

2022 in science (49,037 words) [view diff] exact match in snippet view article find links to article

Duggan, Anne (May 2022). "Tbx2 is a master regulator of inner versus outer hair cell differentiation". Nature. 605 (7909): 298–303. Bibcode:2022Natur.605.

Grainyhead-like gene family (3,243 words) [view diff] exact match in snippet view article find links to article

skin's immune system. Knockout of grhl1 in zebrafish has shown to cause hair cell apoptosis within the inner ear which leads to sensory epithelium damage

Cordon-bleu protein (2,680 words) [view diff] exact match in snippet view article find links to article

Kessels MM, Englert C, Qualmann B (January 2013). "Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2

CSNK1D (14,740 words) [view diff] case mismatch in snippet view article find links to article

Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development". The Journal of Biological Chemistry. 291 (40): 21096–21109