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searching for Guanine nucleotide exchange factor 130 found (225 total)

alternate case: guanine nucleotide exchange factor

RABIF (531 words) [view diff] exact match in snippet view article find links to article

Guanine nucleotide exchange factor MSS4 is a protein that in humans is encoded by the RABIF gene. The Sec4/Rab-related small GTP-binding proteins are involved

ARHGEF3 (551 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human gene. Rho GTPases play a fundamental role in numerous cellular processes

GBF1 (881 words) [view diff] exact match in snippet view article find links to article

Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene. GRCh38: Ensembl release

TRIO (gene) (1,025 words) [view diff] exact match in snippet view article

kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains". Proceedings of the National Academy of Sciences

RAPGEF6 (416 words) [view diff] exact match in snippet view article find links to article

Rap guanine nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF6 gene. GRCh38: Ensembl release 89: ENSG00000158987 – Ensembl

MCF2L (681 words) [view diff] exact match in snippet view article find links to article

Guanine nucleotide exchange factor DBS is a protein that in humans is encoded by the MCF2L gene. GRCh38: Ensembl release 89: ENSG00000126217 – Ensembl

PLEKHG2 (1,151 words) [view diff] exact match in snippet view article find links to article

and PLEKHG2 having this domain also acts as a Rho-specific guanine nucleotide exchange factor (RhoGEF). Activation of RhoGTPase reconstitute the actin cytoskeleton

ARHGEF10 (566 words) [view diff] exact match in snippet view article find links to article

The human ARHGEF10 gene encodes the protein Rho guanine nucleotide exchange factor 10. Rho GTPases play a fundamental role in numerous cellular processes

ARHGEF9 (510 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor 9 is a protein that in humans is encoded by the ARHGEF9 gene. ARHGEF9 belongs to a family of Rho-like GTPases that

ARHGEF35 (59 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor (GEF) 35 is a protein in humans that is encoded by the ARHGEF35 gene. ENSG00000288422 GRCh38: Ensembl release 89:

ARHGEF4 (475 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene. Rho GTPases play a fundamental role in numerous cellular

EF-Ts (1,097 words) [view diff] exact match in snippet view article find links to article

TSFM. It is similar to eukaryotic EF-1B. EF-Ts serves as the guanine nucleotide exchange factor for EF-Tu (elongation factor thermo unstable), catalyzing

T-cell lymphoma invasion and metastasis-inducing protein 1 (1,315 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor TIAM1 is a protein that in humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit

RAPGEF4 (2,724 words) [view diff] exact match in snippet view article find links to article

Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), also known as exchange protein directly activated by cAMP 2 (EPAC2) is a protein that in humans

EIF2B4 (967 words) [view diff] no match in snippet view article find links to article

Wilmer T, Jefferson LS, Proud CG (Nov 1996). "eIF2B, the guanine nucleotide-exchange factor for eukaryotic initiation factor 2. Sequence conservation

GEFT (508 words) [view diff] exact match in snippet view article find links to article

S2CID 2418867. Bryan BA, Cai Y, Liu M (2006). "The Rho-family guanine nucleotide exchange factor GEFT enhances retinoic acid- and cAMP-induced neurite outgrowth"

ARHGEF5 (554 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the ARHGEF5 gene. Rho GTPases play a fundamental role in numerous cellular

ARHGEF2 (1,134 words) [view diff] exact match in snippet view article find links to article

Rho guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ARHGEF2 gene. Rho GTPases play a fundamental role in numerous cellular

RAPGEF3 (3,461 words) [view diff] exact match in snippet view article find links to article

guanine nucleotide exchange factor 3 also known as exchange factor directly activated by cAMP 1 (EPAC1) or cAMP-regulated guanine nucleotide exchange

RIC8A (931 words) [view diff] exact match in snippet view article find links to article

"Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". J. Biol. Chem. 278 (10). United States: 8356–62. doi:10

GRAP (621 words) [view diff] exact match in snippet view article find links to article

BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3

ARFGEF2 (1,103 words) [view diff] no match in snippet view article find links to article

PMID 10212200. "Entrez Gene: ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)". Yamaji R, Adamik R, Takeda K,

DEF6 (467 words) [view diff] exact match in snippet view article find links to article

receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse". The Journal of Biological

CYTH2 (1,129 words) [view diff] exact match in snippet view article find links to article

Frank S, Upender S, Hansen SH, Casanova JE (1998). "ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6". J. Biol. Chem. 273 (1): 23–7

RAB18 (1,270 words) [view diff] no match in snippet view article find links to article

The RAB3GAP1 and RAB3GAP2 proteins interact and create a guanine–nucleotide exchange factor complex that activates RAB18. The TBC1D20 protein may inactivate

EIF2B2 (1,121 words) [view diff] exact match in snippet view article find links to article

1996). "Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2". Mol

CTNNAL1 (522 words) [view diff] exact match in snippet view article find links to article

A, Testa JR, Toksoz D (Nov 2002). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1

FARP2 (496 words) [view diff] exact match in snippet view article find links to article

Hosokawa K, Tohyama M (Oct 2002). "A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling"

PREX2 (484 words) [view diff] no match in snippet view article find links to article

Hawkins PT, Stephens LR, Welch HC (August 2004). "P-Rex2, a new guanine-nucleotide exchange factor for Rac". FEBS Lett. 572 (1–3): 172–6. doi:10.1016/j.febslet

ARFRP1 (733 words) [view diff] exact match in snippet view article find links to article

(ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase

Housekeeping gene (4,612 words) [view diff] exact match in snippet view article find links to article

ARHGEF10L Rho guanine nucleotide exchange factor 10L ARHGEF11 Rho guanine nucleotide exchange factor 11 ARHGEF40 Rho guanine nucleotide exchange factor 40 ARHGEF7

RASGRF2 (607 words) [view diff] exact match in snippet view article find links to article

(1997). "Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras". Mol. Cell. Biol. 17 (3): 1396–406. doi:10.1128/mcb

ARF6 (1,429 words) [view diff] exact match in snippet view article find links to article

Frank S, Upender S, Hansen SH, Casanova JE (1998). "ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6". J. Biol. Chem. 273 (1): 23–7

RANBP3 (805 words) [view diff] exact match in snippet view article find links to article

(May 2002). "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor". J. Biol. Chem. 277 (20): 17385–8. doi:10.1074/jbc.C100620200

PPP1R9B (997 words) [view diff] exact match in snippet view article find links to article

"Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin". J. Biol. Chem

CENTG1 (971 words) [view diff] exact match in snippet view article find links to article

Snyder SH (2002). "Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE". Nature. 415 (6871): 541–4. doi:10

ARFGEF1 (1,092 words) [view diff] no match in snippet view article find links to article

PMID 8917509. "Entrez Gene: ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)". Padilla PI, Chang MJ, Pacheco-Rodriguez

TBC domain (1,127 words) [view diff] exact match in snippet view article find links to article

Panniers R, Henshaw EC (1988). "The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic

EF1 guanine nucleotide exchange domain (286 words) [view diff] exact match in snippet view article find links to article

EF1_GNE yeast guanine nucleotide exchange factor eef1balpha k205a mutant in complex with eef1a Identifiers Symbol EF1_GNE Pfam PF00736 InterPro IPR014038

Retinitis pigmentosa GTPase regulator (2,273 words) [view diff] exact match in snippet view article find links to article

Wright A (May 1996). "A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3)". Nature

SHANK2 (1,590 words) [view diff] exact match in snippet view article find links to article

interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42". The Journal of Biological Chemistry.

SPTBN5 (363 words) [view diff] exact match in snippet view article find links to article

Chardin P, Camonis JH, Gale NW, et al. (1993). "Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2". Science. 260 (5112): 1338–43

SHANK1 (1,900 words) [view diff] exact match in snippet view article find links to article

interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42". The Journal of Biological Chemistry.

EIF2B3 (921 words) [view diff] exact match in snippet view article find links to article

A, Schiffmann R, Hugendubler L, et al. (2005). "Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients". Eur. J. Hum. Genet. 12

Coiled-coil domain containing 124 (126 words) [view diff] exact match in snippet view article find links to article

centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis". PLOS ONE. 8 (7): e69289

Centralspindlin (585 words) [view diff] no match in snippet view article find links to article

RacGAP1 recruits ECT2 to the central spindle. ECT2 is a Guanine nucleotide-exchange factor for RhoA. Cytokinesis is initiated when RhoA is activated

EIF2B1 (1,002 words) [view diff] exact match in snippet view article find links to article

(1996). "Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2". Mol

CLN8 (894 words) [view diff] no match in snippet view article find links to article

Myelination of Peripheral Nerves Associated with Mutant Rho Guanine-Nucleotide Exchange Factor 10". Am. J. Hum. Genet. 73 (4): 926–32. doi:10.1086/378159

Obscurin (2,500 words) [view diff] exact match in snippet view article find links to article

E, Gautel M (Jul 2001). "Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly". The Journal of Cell

Spermatogenesis associated 13 (300 words) [view diff] no match in snippet view article find links to article

(December 2007). "Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42". Oncogene. 26 (55): 7620–267

RAB8B (424 words) [view diff] exact match in snippet view article find links to article

(2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral". J. Biol. Chem. 275 (38): 29761–6. doi:10.1074/jbc

PLEKHG4 (644 words) [view diff] no match in snippet view article find links to article

the gene encoding a protein with spectrin repeat and Rho guanine-nucleotide exchange-factor domains". Am J Hum Genet. 77 (2): 280–96. doi:10.1086/432518

PACSIN1 (578 words) [view diff] exact match in snippet view article find links to article

E, Baranes D, Plomann M, et al. (Jul 2001). "The Ras/Rac guanine nucleotide exchange factor mammalian Son-of-sevenless interacts with PACSIN 1/syndapin

PLEKHG5 (380 words) [view diff] exact match in snippet view article find links to article

A, Geyer R, Johnston L, et al. (December 2013). "The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote

G beta-gamma complex (3,160 words) [view diff] exact match in snippet view article find links to article

inflammation. The Gβγ subunit has been shown to activate a Rho guanine nucleotide exchange factor (RhoGef) gene PLEKHG2 which is upregulated in a number of

ANKRD27 (535 words) [view diff] exact match in snippet view article find links to article

Zhang X, He X, Fu XY, Chang Z (Mar 2006). "Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics". J Cell Sci. 119 (Pt 6):

RHOB (1,246 words) [view diff] exact match in snippet view article find links to article

Der CJ, Burridge K, Wennerberg K (November 2002). "XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC". The Journal of Biological

Rab (G-protein) (1,327 words) [view diff] exact match in snippet view article

and an active form bound to GTP (guanosine triphosphate). A guanine nucleotide exchange factor (GEF) catalyzes the conversion from GDP-bound to GTP-bound

EEF1D (1,395 words) [view diff] exact match in snippet view article find links to article

aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat

MTG1 (651 words) [view diff] exact match in snippet view article find links to article

"Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras". J. Biol. Chem

Guanosine diphosphate (713 words) [view diff] case mismatch in snippet view article find links to article

nucleus through its bind to a nuclear transport factor, where a Guanine Nucleotide Exchange Factor Protein can come to catalyze the exchange of GTP for GDP.

Neurite (1,428 words) [view diff] case mismatch in snippet view article find links to article

Wen-Cai; Ip, Nancy Y.; Shi, Lei (2013-07-05). "The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation

RCBTB1 (577 words) [view diff] exact match in snippet view article find links to article

characterization of E4.5, a novel chromosome condensation regulator-like guanine nucleotide exchange factor". Leuk. Lymphoma. 44 (9): 1579–85. doi:10.3109/10428190309178782

RHOJ (457 words) [view diff] exact match in snippet view article find links to article

et al. (2005). "Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes". FEBS Lett. 579 (5):

GNAQ (1,478 words) [view diff] exact match in snippet view article find links to article

"Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". J. Biol. Chem. 278 (10): 8356–62. doi:10.1074/jbc.M211862200

GNAI2 (1,517 words) [view diff] exact match in snippet view article find links to article

"Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". The Journal of Biological Chemistry. 278 (10): 8356–62.

MYCBP (820 words) [view diff] no match in snippet view article find links to article

the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors". Genes to Cells. 11 (8): 949–59

GNG2 (1,092 words) [view diff] exact match in snippet view article find links to article

(2003). "G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen

Nerve growth factor (2,872 words) [view diff] exact match in snippet view article find links to article

protein kinase (MAPK) kinase. In this pathway, recruitment of a guanine nucleotide exchange factor by the adaptor and docking proteins leads to activation of

GRIPAP1 (608 words) [view diff] exact match in snippet view article find links to article

encoded by the GRIPAP1 gene. GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated

EIF2S1 (1,448 words) [view diff] exact match in snippet view article find links to article

1996). "Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2". Molecular

Elongation factor (791 words) [view diff] exact match in snippet view article find links to article

free site of the ribosome. EF-Ts eEF-1B (βγ) serves as the guanine nucleotide exchange factor for EF-Tu, catalyzing the release of GDP from EF-Tu. EF-G

GABBR2 (1,163 words) [view diff] exact match in snippet view article find links to article

formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins". J. Neurosci. 22 (4): 1280–9. doi:10.1523/JNEUROSCI

RGL2 (757 words) [view diff] case mismatch in snippet view article find links to article

t e PDB gallery 1rlf: STRUCTURE DETERMINATION OF THE RAS-BINDING DOMAIN OF THE RAL-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR RLF, NMR, 10 STRUCTURES

Exocyst complex component 6b (337 words) [view diff] exact match in snippet view article find links to article

X, Hong Y, Huang S, Peränen J, Guo W (May 2012). "A Rab8 guanine nucleotide exchange factor-effector interaction network regulates primary ciliogenesis"

RCC2 (733 words) [view diff] exact match in snippet view article find links to article

structural similarity to RCC1, and has been shown to have weak guanine nucleotide exchange factor (GEF) activity on the small GTPase Rac. TD-60 has also been

GNAI1 (1,434 words) [view diff] exact match in snippet view article find links to article

"Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". The Journal of Biological Chemistry. 278 (10): 8356–62.

GNAI3 (1,641 words) [view diff] exact match in snippet view article find links to article

"Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". The Journal of Biological Chemistry. 278 (10): 8356–62.

DLGAP2 (939 words) [view diff] no match in snippet view article find links to article

myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10". Am. J. Hum. Genet. 73 (4): 926–32. doi:10.1086/378159

ADCY5 (997 words) [view diff] exact match in snippet view article find links to article

(2007). "Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor". Biochem J. 406 (3): 383–8. doi:10.1042/BJ20070512. PMC 2049038

GNAO1 (1,373 words) [view diff] exact match in snippet view article find links to article

"Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor". J. Biol. Chem. 278 (10): 8356–62. doi:10.1074/jbc.M211862200

RASGRP2 (682 words) [view diff] exact match in snippet view article find links to article

A, Matsuda M, Housman DE, Graybiel AM (Nov 1998). "A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia". Proc Natl Acad Sci

RAB3A (1,256 words) [view diff] exact match in snippet view article find links to article

X, Jain S, Sawa A, Snyder SH (2001). "GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate

TRIOBP (853 words) [view diff] exact match in snippet view article find links to article

a novel F-actin binding protein, associates with the Trio guanine nucleotide exchange factor and regulates actin cytoskeletal organization". J Cell Sci

Chromosome 20 (1,573 words) [view diff] no match in snippet view article find links to article

membrane-associated protein ARFGEF2: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) BCAS1: Breast carcinoma-amplified

RAP2A (1,057 words) [view diff] exact match in snippet view article find links to article

"Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras". The Journal

LPAR1 (1,140 words) [view diff] exact match in snippet view article find links to article

activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1". J. Biol. Chem. 278 (1): 400–6. doi:10.1074/jbc.M210151200

SH2B2 (994 words) [view diff] exact match in snippet view article find links to article

protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity". Oncogene. 21 (50): 7720–9

USP8 (920 words) [view diff] exact match in snippet view article find links to article

UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1". The Journal of Biological Chemistry.

GoLoco motif (666 words) [view diff] no match in snippet view article find links to article

"The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor". Trends Biochem. Sci. 24 (9): 340–1. doi:10.1016/s0968-0004(99)01441-3

PTPRF (1,451 words) [view diff] exact match in snippet view article find links to article

kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains". Proc. Natl. Acad. Sci. U.S.A. 93 (11): 5466–71.

EXOC2 (916 words) [view diff] exact match in snippet view article find links to article

Ponstingl H (Dec 2002). "DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates

USO1 (1,111 words) [view diff] no match in snippet view article find links to article

membrane-tethering protein p115 interacts with GBF1, an ARF guanine-nucleotide-exchange factor". EMBO Rep. 4 (3): 320–5. doi:10.1038/sj.embor.embor762. PMC 1315890

Alfred Wittinghofer (1,018 words) [view diff] no match in snippet view article find links to article

Wittinghofer, Alfred; Bos, Johannes L. (1998). "Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP". Nature. 396 (6710): 474–477

David Schlaepfer (825 words) [view diff] exact match in snippet view article find links to article

(14 January 2008). "PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell

ARFGAP1 (1,074 words) [view diff] exact match in snippet view article find links to article

Gulbis JM, Goldberg J (February 1998). "Structure of the guanine nucleotide exchange factor Sec7 domain of human arno and analysis of the interaction

Dishevelled (1,387 words) [view diff] exact match in snippet view article find links to article

of morphogenesis 1). This complex then interacts with Rho guanine nucleotide exchange factor WGEF (weak-similarity GEF), which activates downstream effectors

RASSF9 (1,169 words) [view diff] exact match in snippet view article find links to article

determination of the Ras-binding domain of the Ral-specific guanine nucleotide exchange factor Rlf". Biochemistry. 37 (39): 13453–62. doi:10.1021/bi9811664

RhoC (1,931 words) [view diff] exact match in snippet view article find links to article

Arthur WT, Ellerbroek SM, Der CJ, et al. (2003). "XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC". J. Biol. Chem. 277 (45):

Polo-like kinase (1,508 words) [view diff] no match in snippet view article find links to article

spindle midzone, thereby allowing the recruitment of the Rho guanine nucleotide-exchange factor (GEF) ECT2 to promote RhoA activation and thus actomyosin

RGS2 (1,682 words) [view diff] exact match in snippet view article find links to article

activate the intracellular affectors phospholipase Cβ and rho guanine nucleotide exchange factor to stimulate cell processes which lead to cardiomyocyte hypertrophy

CYTH3 (728 words) [view diff] exact match in snippet view article find links to article

Boretto J, Robineau S, et al. (1998). "ARNO3, a Sec7-domain guanine nucleotide exchange factor for ADP ribosylation factor 1, is involved in the control

ARF1 (1,380 words) [view diff] exact match in snippet view article find links to article

Frank S, Upender S, Hansen SH, Casanova JE (1998). "ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6". J. Biol. Chem. 273 (1): 23–7

SHANK3 (1,565 words) [view diff] exact match in snippet view article find links to article

interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42". The Journal of Biological Chemistry.

TNK2 (1,756 words) [view diff] exact match in snippet view article find links to article

S2CID 16876663. Kato J, Kaziro Y, Satoh T (2000). "Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation". Biochem

Ran (protein) (1,948 words) [view diff] case mismatch in snippet view article

exchange factor for Ran. RCC1 is also known as RanGEF (Ran Guanine nucleotide Exchange Factor). Ran's intrinsic GTPase-activity is activated through interaction

C13orf38 (842 words) [view diff] exact match in snippet view article find links to article

ubiquitin ligase activity; Ring finger proteins 0.559 VAV3 Guanine nucleotide exchange factor VAV3; Exchange factor for GTP-binding proteins RhoA, RhoG

HRAS (1,338 words) [view diff] case mismatch in snippet view article find links to article

example RasGAP. In turn HRAS can bind to proteins of the Guanine Nucleotide Exchange Factor (GEF) class, for example SOS1, which forces the release of

SBDS (1,580 words) [view diff] exact match in snippet view article find links to article

Identifiers Aliases SBDS, SDS, SWDS, CGI-97, SBDS ribosome assembly guanine nucleotide exchange factor, ribosome maturation factor, SBDS ribosome maturation factor

Chromosome 7 (2,949 words) [view diff] exact match in snippet view article find links to article

mitochondrial acylglycerol kinase ARHGEF35: encoding protein Rho guanine nucleotide exchange factor (GEF) 35 AVL9: encoding protein Avl9 cell migration associated

HCK (2,331 words) [view diff] exact match in snippet view article find links to article

and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic

Hereditary gingival fibromatosis (2,052 words) [view diff] no match in snippet view article find links to article

son-of-sevenless gene, is responsible for this disease. SOS1 is a guanine nucleotide-exchange factor that functions in the transduction of signals that control

Chromosome 21 (3,077 words) [view diff] exact match in snippet view article find links to article

factor 2 TFF3: encoding protein trefoil factor 3 TIAM1: Rho guanine nucleotide exchange factor TIAM1 TMPRSS2: encoding enzyme transmembrane protease serine

RALA (2,012 words) [view diff] exact match in snippet view article find links to article

2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral". The Journal of Biological Chemistry. 275 (38): 29761–6

Restriction point (2,768 words) [view diff] exact match in snippet view article find links to article

kinase cascades. RTK-associated Grb2 binds Sos, which is a guanine nucleotide exchange factor that converts membrane-bound Ras to its active form (Ras-GDP

Ohio State University College of Medicine (1,743 words) [view diff] exact match in snippet view article find links to article

(February 2000). "Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia"

Metabotropic glutamate receptor 3 (3,074 words) [view diff] exact match in snippet view article find links to article

formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins". The Journal of Neuroscience. 22 (4): 1280–9.

Spindle apparatus (3,300 words) [view diff] exact match in snippet view article find links to article

biophysical properties of the cross-linking motor proteins. The guanine nucleotide exchange factor for the small GTPase Ran (Regulator of chromosome condensation

Embryonal fyn-associated substrate (4,850 words) [view diff] exact match in snippet view article find links to article

scaffold for other proteins including CRK proteins and C3G, a guanine nucleotide exchange factor (GEF) for RAP1. PTP-PEST, a soluble protein tyrosine phosphatase

Leukoencephalopathy with vanishing white matter (2,511 words) [view diff] no match in snippet view article find links to article

failure, she does not necessarily have VWM. eIF2B is the guanine nucleotide-exchange factor for eIF2, and is composed of 5 subunits. The largest subunit

Philadelphia chromosome (3,538 words) [view diff] exact match in snippet view article find links to article

cluster region, a gene which encodes a protein that acts as a guanine nucleotide exchange factor for Rho GTPase proteins. Translocation results in an oncogenic

Titin (4,680 words) [view diff] exact match in snippet view article find links to article

Gautel M (July 2001). "Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly". The Journal of Cell

Insulin receptor substrate 1 (4,304 words) [view diff] exact match in snippet view article find links to article

Formation of the Grb-2/Sos complex, also known as the RAS guanine nucleotide exchange factor complex, results in ERK1/2 activation. IRS-1 signal transduction

Alexander Silberman Institute of Life Sciences (2,100 words) [view diff] exact match in snippet view article find links to article

cyclase. Demonstrating that the β-adrenergic receptor acts as a guanine nucleotide exchange factor facilitating GDP/GTP exchange to activate adenylyl cyclase

C8orf34 (2,310 words) [view diff] no match in snippet view article find links to article

The nearest protein-encoding gene to C8orf34 is PREX2, a guanine-nucleotide exchange factor for the Rac family of G proteins. This protein is involved

Bacterial effector protein (3,272 words) [view diff] case mismatch in snippet view article find links to article

January 2012). "The Interplay between the Escherichia coli Rho Guanine Nucleotide Exchange Factor Effectors and the Mammalian RhoGEF Inhibitor EspH". mBio.

Colony stimulating factor 1 receptor (4,593 words) [view diff] no match in snippet view article find links to article

Dok3 Downstream of kinase-1, -2, -3; adaptors Vav Rho family guanine-nucleotide-exchange factor BLIMP-1 B-lymphocyte-induced maturation protein-1; transcriptional

Myc (6,672 words) [view diff] exact match in snippet view article find links to article

Kamo T, Kitanaka C, Kuchino Y, Sugimura H (February 2003). "Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated

Spindle checkpoint (9,145 words) [view diff] exact match in snippet view article find links to article

kinetochores to the spindle. Bound to the chromatin is a Ran guanine nucleotide exchange factor (GEF) that stimulates cytosolic Ran near the chromosome to

NEDD9 (8,012 words) [view diff] exact match in snippet view article find links to article

MM, Hanafusa H (1998). "Direct binding of p130(Cas) to the guanine nucleotide exchange factor C3G". J. Biol. Chem. 273 (40): 25673–9. doi:10.1074/jbc.273