Find link

language:

Find link is a tool written by Edward Betts.

searching for Fatty acid synthesis 93 found (213 total)

Malonyl-CoA (574 words) [view diff] exact match in snippet view article find links to article

(ACP). Malonyl-CoA is formed in the first step of mitochondrial fatty acid synthesis (mtFASII) from malonic acid by malonyl-CoA synthetase (ACSF3). MCAT

Decarboxylation (1,289 words) [view diff] exact match in snippet view article find links to article

α-ketoglutarate α-ketoglutarate to succinyl-CoA. Straight-chain fatty acid synthesis occurs by recurring reactions involving decarboxylation of malonyl-CoA

Ketoacyl synthase (2,238 words) [view diff] exact match in snippet view article find links to article

malonyl-ACP to form 3-ketoacyl-ACP. This reaction is a key step in the fatty acid synthesis cycle, as the resulting acyl chain is two carbon atoms longer than

Rhizobium leguminosarum (519 words) [view diff] no match in snippet view article find links to article

Rhizobium leguminosarum is a bacterium which lives in a mutualistic symbiotic relationship with legumes, and has the ability to fix free nitrogen from

Coenzyme A (2,528 words) [view diff] exact match in snippet view article find links to article

of acetyl-CoA carboxylase, which catalyzes the committed step in fatty acid synthesis. Insulin stimulates acetyl-CoA carboxylase, while epinephrine and

Earl Reece Stadtman (804 words) [view diff] no match in snippet view article find links to article

field. Early in his career he worked with Horace Barker on bacterial fatty-acid synthesis, with a series of four papers. In the same period he collaborated

Cyclic di-AMP (2,035 words) [view diff] exact match in snippet view article find links to article

β-lactams) and reduced cellular turgor. Cyclic di-AMP has been linked to fatty acid synthesis regulation in Mycobacterium smegmatis, the growth of S. aureus in

Carnitine palmitoyltransferase I (2,464 words) [view diff] exact match in snippet view article find links to article

by malonyl CoA, the first committed intermediate produced during fatty acid synthesis. Its role in fatty acid metabolism makes CPT1 important in many metabolic

Tumor metabolome (2,581 words) [view diff] exact match in snippet view article find links to article

isocitrate binding in the active site of the proteins of IDH1 and IDH2. Fatty acid synthesis is an anabolic process that starts from the conversion of acetyl-CoA

Planctomycetaceae (891 words) [view diff] exact match in snippet view article find links to article

Planctomycetaceae species are generally aerobic, but are uniquely classified by fatty acid synthesis and stalk-like formations. When compared to other species of the

Metabolon (885 words) [view diff] exact match in snippet view article find links to article

mass spectrometry and visualized by cryo-electron microscopy. The Fatty acid synthesis metabolon in C. thermophilum is highly flexible, and although a high-resolution

MECR (663 words) [view diff] exact match in snippet view article find links to article

that involves disruptions in the pathway involved in mitochondrial fatty acid synthesis (mtFAS). MEPAN patients were found to harbor recessive mutations

Cerulenin (567 words) [view diff] exact match in snippet view article find links to article

natural product antibiotic known to inhibit lipid synthesis. In fatty acid synthesis, it has been reported to bind in equimolar ratio to b-keto-acyl-ACP

Acetate pathway (248 words) [view diff] exact match in snippet view article find links to article

from malonyl-CoA, to form increasingly longer carbon chains. In fatty acid synthesis, these chains are fully reduced after each elongation step, while

Pseudohypoxia (875 words) [view diff] exact match in snippet view article find links to article

cycle function), and increased NADH all contribute to increased fatty acid synthesis within the liver (which in excess causes fatty liver disease). Pseudohypoxia

Cyclopropane fatty acid (561 words) [view diff] exact match in snippet view article find links to article

fatty acid synthase family and their contribution to cyclopropane fatty acid synthesis". BMC Plant Biology. 11 (1): 97. doi:10.1186/1471-2229-11-97. PMC 3132707

Salih J. Wakil (563 words) [view diff] exact match in snippet view article find links to article

CoA Carboxylase and Fatty Acid Synthetase, the two key enzymes of fatty acid synthesis. Wakil eventually left UWM in the same year to join the biochemistry

Transketolase (1,751 words) [view diff] exact match in snippet view article find links to article

especially in tissues actively engaged in biosyntheses, such as fatty acid synthesis by the liver and mammary glands, and for steroid synthesis by the

Rodolfo Brenner (999 words) [view diff] case mismatch in snippet view article find links to article

Regulatory Function of Δ6 Desaturase — Key Enzyme of Polyunsaturated Fatty Acid Synthesis. In: Bazán, N.G., Brenner, R.R., Giusto, N.M. (eds) Function and

Beta-ketoacyl-ACP synthase I (473 words) [view diff] exact match in snippet view article find links to article

PMID 4561013. Toomey RE, Wakil SJ (Mar 1966). "Studies on the mechanism of fatty acid synthesis. XVI. Preparation and general properties of acyl-malonyl acyl carrier

Beta-ketoacyl-ACP synthase III (2,909 words) [view diff] exact match in snippet view article find links to article

biosynthesis system that occurs in plants and bacteria. The role of FabH in fatty acid synthesis has been described in Streptomyces glaucescens, Streptococcus pneumoniae

(acyl-carrier-protein) S-malonyltransferase (1,684 words) [view diff] exact match in snippet view article

thioester forms which are characteristic of acyl intermediates in fatty acid synthesis and which are strictly required for the condensation reactions catalyzed

Beta-ketoacyl-ACP synthase II (371 words) [view diff] exact match in snippet view article find links to article

Escherichia coli Evidence for function in the thermal regulation of fatty acid synthesis". J. Biol. Chem. 255 (8): 3263–5. PMID 6988423. Magnuson K, Carey

Mitochondrion (18,357 words) [view diff] exact match in snippet view article find links to article

tissue is present at birth and decreases with age. Mitochondrial fatty acid synthesis (mtFASII) is essential for cellular respiration and mitochondrial

ACACA (1,218 words) [view diff] exact match in snippet view article find links to article

carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different

Palmitoyl-CoA hydrolase (813 words) [view diff] exact match in snippet view article find links to article

hypoglycemia. Barnes EM Jr; Wakil SJ (1968). "Studies on the mechanism of fatty acid synthesis. XIX. Preparation and general properties of palmityl thioesterase"

Biosynthesis (6,770 words) [view diff] exact match in snippet view article find links to article

located within a single cellular organelle (e.g., mitochondrial fatty acid synthesis pathways), while others involve enzymes that are located across an

Elaioplast (999 words) [view diff] case mismatch in snippet view article find links to article

Exchange Translocator Imports Carbon across the Leucoplast Envelope for Fatty Acid Synthesis in Developing Castor Seed Endosperm". Plant Physiology. 114 (3):

Bietti's crystalline dystrophy (476 words) [view diff] exact match in snippet view article find links to article

the human gene. These genes code for cytochrome P450s involved in fatty acid synthesis. At this time, there is no treatment for BCD. Genetic studies are

Ramoplanin (700 words) [view diff] exact match in snippet view article find links to article

peptide synthetase genes and supporting enzymes for amino acid and fatty acid synthesis, revealed by sequencing of the producer strain in 2002. Initial investigation

HRAC classification (601 words) [view diff] exact match in snippet view article find links to article

Quinoline-carboxylates J K3 / N 15 Inhibits very long chain fatty acid synthesis Prosulfocarb, Ethofumesate Thiocarbamates, Benzofurans J - Unknown

Pimelic acid (389 words) [view diff] case mismatch in snippet view article find links to article

Biotin Synthesis Pathway, Exists as the Free Acid and Is Assembled by Fatty Acid Synthesis". Molecular Microbiology. 104 (4): 595–607. doi:10.1111/mmi.13648

Cytosol (4,692 words) [view diff] exact match in snippet view article find links to article

localization of pathways can be different in other organisms, for instance fatty acid synthesis occurs in chloroplasts in plants and in apicoplasts in apicomplexa

Glucose 6-phosphate (966 words) [view diff] exact match in snippet view article find links to article

produce more NADPH (a reducing agent for several reactions like fatty acid synthesis and glutathione reduction in erythrocytes). This will cause the G6P

Valerie Mizrahi (541 words) [view diff] case mismatch in snippet view article find links to article

profile for Valerie Mizrahi (Q22006961). Effects of Pyrazinamide on Fatty Acid Synthesis by Whole Mycobacterial Cells and Purified Fatty Acid Synthase I.

Conjugated fatty acid (500 words) [view diff] case mismatch in snippet view article find links to article

Xiao-Hong; Sweet, Marie; Shanklin, John (26 March 2012). "Conjugated Fatty Acid Synthesis". Journal of Biological Chemistry. 287 (20): 16230–16237. doi:10

Neurofibromatosis type II (3,350 words) [view diff] exact match in snippet view article find links to article

Chernoff J (May 2018). "A new concept in NF2 pharmacotherapy: targeting fatty acid synthesis". Oncoscience. 5 (5–6): 126–127. doi:10.18632/oncoscience.417. PMC 6049319

Ternatin heptapeptide (82 words) [view diff] exact match in snippet view article find links to article

mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A(y) mice". Biochemical and Biophysical

Very-long-chain enoyl-CoA reductase (299 words) [view diff] exact match in snippet view article find links to article

Enoyl-CoA reductase gene reveal an essential role for very-long-chain fatty acid synthesis in cell expansion during plant morphogenesis". The Plant Cell. 17

Enoyl-(acyl-carrier-protein) reductase (NADPH, A-specific) (192 words) [view diff] exact match in snippet view article

phosphate to the acyl chain in the dehydrogenase-catalyzed reactions of fatty acid synthesis". J. Biol. Chem. 245 (23): 6312–6. PMID 4394955. Portal: Biology

Acetoacetyl-CoA reductase (197 words) [view diff] exact match in snippet view article find links to article

Wakil S, Bressler R (March 1962). "Studies on the mechanism of fatty acid synthesis. X. Reduced triphosphopyridine nucleotide-acetoacetyl coenzyme A

Icosanoyl-CoA synthase (230 words) [view diff] exact match in snippet view article find links to article

Bessoule JJ, Lessire R, Rigoulet M, Guerin B, Cassagne C (1987). "Fatty acid synthesis in mitochondria from Saccharomyces cerevisiae". FEBS Lett. 214 (1):

Pyruvate dehydrogenase (NADP+) (526 words) [view diff] exact match in snippet view article

role of oxygen-sensitive pyruvate dehydrogenase in mitochondrial fatty acid synthesis in Euglena gracilis". Archives of Biochemistry and Biophysics. 237

Lipoic acid (4,967 words) [view diff] exact match in snippet view article find links to article

methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency, mitochondrial fatty acid synthesis (mtFASII), which is the precursor reaction of lipoic acid biosynthesis

Jagannath Ganguly (3,901 words) [view diff] exact match in snippet view article find links to article

Ganguly, Arch. Biochem. Biophys., 83, 371–375. On the mechanism of fatty acid synthesis: Salih J. Wakil and J. Ganguly, J. Am. Chem. Soc., 81, 2597. The

Máté Hidvégi (1,129 words) [view diff] exact match in snippet view article find links to article

decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells. Pancreas 23: 141-147, 2001

Acyl-CoA dehydrogenase (NADP+) (279 words) [view diff] exact match in snippet view article

Kramer R, Ohly B (1968). "On the mechanism of malonyl-CoA-independent fatty acid synthesis. I The mechanism of elongation of long-chain fatty acids by acetyl-CoA"

Rhamnolipid (3,580 words) [view diff] exact match in snippet view article find links to article

encodes the NADPH-dependent β-keto-acyl-ACP reductase required for fatty acid synthesis. It is a member of the FASII cycle along with FabI and FabA, which

Platensimycin (1,253 words) [view diff] case mismatch in snippet view article find links to article

Capuano, B (2008). "Platensimycin: A Promising Antimicrobial Targeting Fatty Acid Synthesis". Current Medicinal Chemistry. 15 (7): 705–10. doi:10.2174/092986708783885255

(acyl-carrier-protein) S-acetyltransferase (399 words) [view diff] exact match in snippet view article

PMID 4698221. Williamson IP, Wakil SJ (1966). "Studies on the mechanism of fatty acid synthesis. XVII. Preparation and general properties of acetyl coenzyme A and

EIF6 (1,816 words) [view diff] exact match in snippet view article find links to article

production of ribosome. The activity of eIF6 also cause glycolysis and fatty acid synthesis by mRNAs' translational controlling. eIF6 is 245 amino acids long

Sterol regulatory element-binding protein 2 (1,450 words) [view diff] exact match in snippet view article find links to article

regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine

Ipsita Roy (544 words) [view diff] exact match in snippet view article find links to article

postdoctoral student at the University of Minnesota, where she worked in fatty acid synthesis. Roy started her independent career at the Indian Institutes of Technology

Enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific) (323 words) [view diff] exact match in snippet view article

PMID 338601. Weeks G, Wakil SJ (1968). "Studies on the mechanism of fatty acid synthesis. 18. Preparation and general properties of the enoyl acyl carrier

Crotonoyl-(acyl-carrier-protein) hydratase (233 words) [view diff] exact match in snippet view article

Weeks G, Toomey RE, Wakil SJ (1968). "Studies on the mechanism of fatty acid synthesis. XX. Preparation and general properties of beta-hydroxybutyryl acyl

3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase (362 words) [view diff] exact match in snippet view article

"Functional replacement of the FabA and FabB proteins of Escherichia coli fatty acid synthesis by Enterococcus faecalis FabZ and FabF homologues". The Journal of

Xiaodong Wang (biochemist) (1,693 words) [view diff] exact match in snippet view article

"SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver". Journal of Clinical Investigation. 109 (9): 1125–1131

Glucose-6-phosphate dehydrogenase (2,413 words) [view diff] exact match in snippet view article find links to article

according to two older publications and might be product inhibition in fatty acid synthesis which requires NADPH. G6PD is negatively regulated by acetylation

Interleukin 19 (1,943 words) [view diff] exact match in snippet view article find links to article

(isolated from a hepatocellular carcinoma patient) and the expression of fatty acid synthesis-related enzymes (reduced lipogenesis). IL-19 is therefore closely

Hydroxocobalamin (2,021 words) [view diff] exact match in snippet view article find links to article

which results in accumulation of methylmalonyl-CoA and aberrant fatty acid synthesis. In the other enzymatic reaction, methylcobalamin supports the methionine

Probico (744 words) [view diff] exact match in snippet view article find links to article

supplementation essential to prevent deficiency. Biotin is crucial in fatty acid synthesis, protein synthesis, nucleic acid synthesis, and the carbon-adding

Biotin carboxylase (1,050 words) [view diff] exact match in snippet view article find links to article

is present in, the enzyme still works to serve the same function. Fatty acid synthesis provides sterols and other lipids essential to biochemical pathways

INSIG2 (1,582 words) [view diff] exact match in snippet view article find links to article

"Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis". Proc. Natl. Acad. Sci. U.S.A. 100 (6): 3155–60. Bibcode:2003PNAS

Triclosan (6,624 words) [view diff] exact match in snippet view article find links to article

bacteriostatic, and it targets bacteria primarily by inhibiting fatty acid synthesis.[citation needed] Triclosan binds to bacterial enoyl-acyl carrier

Janelle Ayres (1,361 words) [view diff] exact match in snippet view article find links to article

Loomba, R., Metallo, C.M. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. (2018) Nature Chemical Biology. 14(11):1021-1031

Pyrazinamide (2,334 words) [view diff] exact match in snippet view article find links to article

HI, Mizrahi V, Barry CE (April 2002). "Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I"

Thraustochytrids (10,922 words) [view diff] exact match in snippet view article find links to article

It is not certain as to why two different pathways are needed for fatty acid synthesis, but studies have shown that auxotrophic thraustochytrids are a direct

Pyrazinamide (2,334 words) [view diff] exact match in snippet view article find links to article

HI, Mizrahi V, Barry CE (April 2002). "Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I"

Organosulfur chemistry (3,035 words) [view diff] exact match in snippet view article find links to article

formed from coenzyme A are prominent in biochemistry, especially in fatty acid synthesis. A sulfoxide, R−S(O)−R, is the S-oxide of a sulfide ("sulfide oxide")

Acetyl-CoA (2,097 words) [view diff] exact match in snippet view article find links to article

the lipid bilayers of all cellular membranes. In plants, de novo fatty acid synthesis occurs in the plastids. Many seeds accumulate large reservoirs of

ACACB (1,341 words) [view diff] exact match in snippet view article find links to article

carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of

Liver X receptor (3,038 words) [view diff] exact match in snippet view article find links to article

suggesting that LXRα and LXRβ have separate roles. LXRs regulate fatty acid synthesis by modulating the expression of sterol regulatory element binding

3-Hydroxypropionate/4-hydroxybutyrate cycle (822 words) [view diff] exact match in snippet view article find links to article

number of metabolic processes, such as the citric acid cycle and fatty acid synthesis. The 3-HP/4-HB cycle is very effective for autotrophic carbon fixation

Cannabinoid receptor (3,086 words) [view diff] exact match in snippet view article find links to article

"Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity". The Journal of Clinical

Pantothenic acid (3,267 words) [view diff] exact match in snippet view article find links to article

the formation of acyl carrier protein (ACP), which is required for fatty acid synthesis. Its synthesis also connects with other vitamins such as thiamin

Nenad Ban (1,553 words) [view diff] exact match in snippet view article find links to article

to our understanding of giant multifunctional enzymes involved in fatty acid synthesis offering mechanistic insights into substrate shuttling and delivery

Carnitine (3,582 words) [view diff] exact match in snippet view article find links to article

increases the concentration of malonyl-CoA, the first intermediate in fatty acid synthesis, leading to the inhibition of carnitine acyltransferase 1, thereby

C-1027 (1,187 words) [view diff] no match in snippet view article find links to article

and their biosynthesis is distinct from other known polyketide and fatty-acid synthesis paradigms. The enediyne PKS, PKSE, from S. globisporusresponsible

Lynn L. Silver (1,521 words) [view diff] exact match in snippet view article find links to article

synthesis, DNA replication, cell wall synthesis, protein synthesis, and fatty acid synthesis. She has contributed to the discovery of new antibacterials to overcome

Anandamide (2,323 words) [view diff] exact match in snippet view article find links to article

"Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity". The Journal of Clinical

Insulin receptor (3,785 words) [view diff] exact match in snippet view article find links to article

influx of glucose (3), glycogen synthesis (4), glycolysis (5), and fatty acid synthesis (6). Signal transduction of Insulin: At the end of the transduction

Dicarboxylic acid (3,151 words) [view diff] exact match in snippet view article find links to article

tob-oxidation, this generates malonyl-CoA which is further used in saturated fatty acid synthesis. The determination of the dicarboxylic acids generated by permanganate-periodate

Auxenochlorella protothecoides (1,449 words) [view diff] exact match in snippet view article find links to article

symporter (HUP)-like genes, in addition to rapid pyruvate synthesis, fatty acid synthesis enzyme upregulation, and fatty acid degradation enzyme downregulation

Fructose (5,342 words) [view diff] exact match in snippet view article find links to article

hepatocytes, converted to acetyl CoA by citrate lyase and directed toward fatty acid synthesis. In addition, DHAP can be converted to glycerol 3-phosphate, providing

Imidacloprid (4,882 words) [view diff] exact match in snippet view article find links to article

neonicotinoid imidacloprid suppresses the entire mevalonate pathway and fatty acid synthesis". J Proteomics. 196: 69–80. doi:10.1016/j.jprot.2018.12.022. PMID 30583045

Micromonas (3,363 words) [view diff] exact match in snippet view article find links to article

acyl-CoA Δ6-desaturase is highly effective in the polyunsaturated fatty acid synthesis pathway due to its strong binding preference for omega-3 substrates

LS9, Inc (2,328 words) [view diff] exact match in snippet view article find links to article

(2008–2013) been pushing patents for specific enzymes involved in fatty acid synthesis and metabolism. This is of particular importance since enzymes are

Protocell (7,479 words) [view diff] exact match in snippet view article find links to article

stability. However, despite this production, the authors state that net fatty acid synthesis would not yield sufficient concentrations for spontaneous membrane

List of human blood components (94 words) [view diff] exact match in snippet view article find links to article

1-10 ×10−6 Biotin (Vitamin H) Gluconeogenesis, metabolize leucine, fatty acid synthesis 7-17 ×10−9 9-16 ×10−9 Blood Urea Nitrogen (BUN) 8-23 ×10−5 Bradykinin

Malaria (26,028 words) [view diff] exact match in snippet view article find links to article

compared to the blood stage. Some of these metabolic pathways are fatty acid synthesis and elongation, tricarboxylic acid, amino acid and heme metabolism

Gestational diabetes (10,821 words) [view diff] exact match in snippet view article find links to article

translocation of Glut-4 transporter to the plasma membrane and influx of glucose (3), glycogen synthesis (4), glycolysis (5) and fatty acid synthesis (6).

Stichodactyla toxin (8,628 words) [view diff] exact match in snippet view article find links to article

glucose uptake and increased β-oxidation of fatty acids, glycolysis, fatty acid synthesis and uncoupling protein 1 expression by brown fat. As a consequence

Cluster of Excellence Frankfurt Macromolecular Complexes (15,449 words) [view diff] exact match in snippet view article find links to article

Fischer M, Boles E, Grininger M (2017). "Engineering fungal de novo fatty acid synthesis for short chain fatty acid production". Nat Commun. 8: 14650. Bibcode:2017NatCo