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searching for Epigenome editing 6 found (57 total)

5-Hydroxymethylcytosine (1,835 words) [view diff] case mismatch in snippet view article find links to article

Base-Resolution Methods for the Detection of 5-Hydroxymethylcytosine in Genomic DNA". Epigenome Editing. Vol. 2842. pp. 325–352. doi:10.1007/978-1-0716-4051-7_17.

CRISPR activation (2,739 words) [view diff] exact match in snippet view article find links to article

Calarco JP, Crabtree GR (September 2017). "Rapid and reversible epigenome editing by endogenous chromatin regulators". Nature Communications. 8 (1):

Eric J. Nestler (3,746 words) [view diff] exact match in snippet view article find links to article

inducible, cell-type specific mutations in mice, and locus-specific epigenome editing to establish causal links between molecular and behavioral phenomena

Cas9 (5,896 words) [view diff] exact match in snippet view article find links to article

Perez AA, Halmai J, Le VM, et al. (September 2017). "dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for

Off-target genome editing (7,115 words) [view diff] exact match in snippet view article find links to article

an epigenetic link which will be explored more for the future of epigenome editing. Variations within the PAM sequence can also affect sgRNA activity

RNA-directed DNA methylation (14,822 words) [view diff] exact match in snippet view article find links to article

manipulation, suggesting that RdDM can be a valuable tool for targeted epigenome editing. Recent work has even bypassed RdDM altogether by artificially tethering