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searching for Epigenome editing 5 found (52 total)

CRISPR activation (2,739 words) [view diff] exact match in snippet view article find links to article

Calarco JP, Crabtree GR (September 2017). "Rapid and reversible epigenome editing by endogenous chromatin regulators". Nature Communications. 8 (1):

Cas9 (5,614 words) [view diff] exact match in snippet view article find links to article

VM, Mackay JP, Farnham PJ, Segal DJ (September 2017). "dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for

Eric J. Nestler (3,748 words) [view diff] exact match in snippet view article find links to article

inducible, cell-type specific mutations in mice, and locus-specific epigenome editing to establish causal links between molecular and behavioral phenomena

Off-target genome editing (6,846 words) [view diff] exact match in snippet view article find links to article

an epigenetic link which will be explored more for the future of epigenome editing. Variations within the PAM sequence can also affect sgRNA activity

RNA-directed DNA methylation (14,822 words) [view diff] exact match in snippet view article find links to article

manipulation, suggesting that RdDM can be a valuable tool for targeted epigenome editing. Recent work has even bypassed RdDM altogether by artificially tethering