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searching for TP53 97 found (241 total)

alternate case: tP53

Breast cancer–related regulator of tp53 (47 words) [view diff] exact match in snippet view article find links to article

Breast cancer-related regulator of TP53 is a protein that in humans is encoded by the BCPR gene. "Human PubMed Reference:". National Center for Biotechnology

ALOX15 (5,728 words) [view diff] exact match in snippet view article find links to article

experiments yielding data that supported the hypothesis that loss of the TP53 gene, or gain-of-function activities resulting from the expression of its

TP53 target 3D (49 words) [view diff] exact match in snippet view article find links to article

TP53 target 3D is a protein that in humans is encoded by the TP53TG3D gene. GRCh38: Ensembl release 89: ENSG00000205456 – Ensembl, May 2017 "Human PubMed

The Cancer Genome Atlas (7,468 words) [view diff] exact match in snippet view article find links to article

cancer in Nature in June 2011. The researchers found mutations of the gene TP53 in an overwhelming 96% of the cases analyzed, Recurrent mutations at lower

EMBiology (227 words) [view diff] exact match in snippet view article find links to article

relationship with TP53 miRNA Effect Inhibitory effect of an miRNA on its mRNA target miR-30 has a negative "miRNAEffect" relationship with TP53 Promoter Binding

Hp53int1 (1,632 words) [view diff] exact match in snippet view article find links to article

direction as TP53 and is present in TP53 protein-rich myeloid leukemia cells HL-60 and U937. This suggests a strong relationship to the TP53 gene and subsequent

Choroid plexus papilloma (2,294 words) [view diff] exact match in snippet view article find links to article

component being investigated. One of the most prevalent mutations in CPTs is the TP53 R248W mutation. Signs of the tumor resulting from increased intracranial

KDM1A (2,086 words) [view diff] exact match in snippet view article find links to article

(H3K4). Other reported methylated lysine substrates such as histone H3K9 and TP53 have not been biochemically validated. This enzyme plays a critical role

Curtis C. Harris (2,466 words) [view diff] exact match in snippet view article find links to article

microbiome – TP53 mutation interaction in human lung cancer, Genome Biology:19: 123–29, 2018. Decades prior to the recent discovery of mutant TP53 cells in

Serous tumour (756 words) [view diff] exact match in snippet view article find links to article

cells are diffusely positive for p53, a pattern consistent with a missense TP53 mutation while the adjacent epithelial cells from the background serous borderline

Rosalind Eeles (603 words) [view diff] exact match in snippet view article find links to article

Mohammed A Khan; Curtis C Harris; Pierre Hainaut (1 June 2002). "The IARC TP53 database: new online mutation analysis and recommendations to users". Human

PPM1A (1,109 words) [view diff] exact match in snippet view article find links to article

phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively

Granulopoiesis (1,916 words) [view diff] exact match in snippet view article find links to article

the dynamics of emergency granulopoiesis, as demonstrated by studies in TP53 haploinsufficient models, particularly in FANCC−/− mice, highlighting the

Venetoclax (2,389 words) [view diff] exact match in snippet view article find links to article

of chronic lymphocytic leukemia (CLL) in the presence of 17p deletion or TP53 mutation in adults who are unsuitable for or have failed a B cell receptor

Cytoplasmic polyadenylation element (1,178 words) [view diff] exact match in snippet view article find links to article

the expression of Myc leads to tumor formation. The tumor suppressor gene TP53 has also been shown to be regulated by a CPE. Cell lines that do not produce

Somatic hypermutation (1,013 words) [view diff] exact match in snippet view article find links to article

(2013). "Critical analysis of strand-biased somatic mutation signatures in TP53 versus Ig genes, in genome -wide data and the etiology of cancer". ISRN Genomics

Prognosis marker (1,215 words) [view diff] exact match in snippet view article find links to article

RET-PTC, NTRK1, PTEN, TP53, PI3K, AKT, CTNNB1, PAX8, RAS, BRAF, TSHR Bladder cancer FGFR3, TERT, STAG2, AURKA Ovarian cancer TP53, WT1, Ki67, Topo-II,

WRAP53 (1,837 words) [view diff] exact match in snippet view article find links to article

Yeager M, Burdett L, et al. (December 2007). "Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer"

TTK (gene) (836 words) [view diff] exact match in snippet view article

Bertheau P, Turpin E, Rickman DS, et al. (2007). "Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin−Cyclophosphamide

Protein tertiary structure (1,603 words) [view diff] case mismatch in snippet view article find links to article

(1): 215–24. doi:10.1007/s00441-004-0938-y. PMID 15503155. S2CID 1824912. "Tp53 Knockout Rat". Cancer. Retrieved 2010-12-18. "Feature – What is Folding and

Mir-145 (1,481 words) [view diff] exact match in snippet view article find links to article

R, Nicoloso MS, Lupini L, et al. (Feb 2010). "miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha

Uterine serous carcinoma (1,179 words) [view diff] exact match in snippet view article find links to article

called serous endometrial intraepithelial carcinoma. Mutation is found in TP53 gene which is a tumor suppressor gene even in precursor lesion suggesting

Inotuzumab ozogamicin (1,248 words) [view diff] case mismatch in snippet view article find links to article

Acute Lymphoblastic Leukemia with High- Risk Molecular Features, Including Tp53 Loss". doi:10.26226/morressier.5ebc261fffea6f735881a254. S2CID 242875059

Deubiquitinating enzyme (4,318 words) [view diff] exact match in snippet view article find links to article

cycle progression is halted to prevent propagation of the mutation. The TP53 gene (also known as p53) is crucial in ensuring the conservation of the genome

Choroid plexus carcinoma (905 words) [view diff] exact match in snippet view article find links to article

syndrome and malignant rhabdoid tumors. A mutation in the tumor suppressor gene TP53 is usually characterized in this disease. Choroid plexus carcinomas typically

Genome (book) (2,052 words) [view diff] exact match in snippet view article

The TP53 gene on chromosome 17 suppresses cancer cells, while oncogenes stimulate cell growth and can cause cancer if kept switched on, while TP53 can

TMSB15A (491 words) [view diff] exact match in snippet view article find links to article

Bertheau P, Turpin E, Rickman DS, et al. (2007). "Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin−Cyclophosphamide

POLG (1,864 words) [view diff] case mismatch in snippet view article find links to article

including 32 co-complex interactions. POLG appears to interact with POLG2, Dlg4, Tp53, and Sod2. GRCh38: Ensembl release 89: ENSG00000140521 – Ensembl, May 2017

Epigenetics of physical exercise (8,910 words) [view diff] exact match in snippet view article find links to article

expression of the tumor suppressor TP53 gene by influencing epigenetic modifications to be made to the cancer cells genome. The TP53 gene codes for the p53 protein

Erica Golemis (710 words) [view diff] exact match in snippet view article find links to article

tumors with patterns of mutation in TP53 and CDKN2A in order to show that patterns of hotspot mutations in TP53 differed depending on the presence or

Astra 2E (1,929 words) [view diff] case mismatch in snippet view article find links to article

Ireland BBC One South East BBC One Yorks & Lincs BBC Three BBC Two England Tp53 10.891 GHz H 22000 5/6: ITV 2 +1hr ITV 3 ITV 4 ITV 1 Border Scotland ITV

RET inhibitor (2,422 words) [view diff] exact match in snippet view article find links to article

KRAS mutations among others. TP53 mutational status appears to have an impact on prognosis and resistance mechanisms, with TP53-mutated tumors showing shorter

ENC1 (830 words) [view diff] exact match in snippet view article find links to article

hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate

Stephen Friend (722 words) [view diff] exact match in snippet view article find links to article

enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions". Molecular and Cellular Biology. 26 (24): 9377–86. doi:10.1128/MCB

Stephen Friend (722 words) [view diff] exact match in snippet view article find links to article

enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions". Molecular and Cellular Biology. 26 (24): 9377–86. doi:10.1128/MCB

High-resolution melting analysis (2,573 words) [view diff] exact match in snippet view article find links to article

primer placement) could be successfully employed to detect mutations in the TP53 gene, which encodes the tumour suppressor protein p53 in clinical samples

Fructose 2,6-bisphosphate (992 words) [view diff] exact match in snippet view article find links to article

activates certain genes by the tumor suppressor p53. One such gene encodes TP53-inducible glycolysis and apoptosis regulator (TIGAR); an enzyme that inhibits

Virtual karyotype (7,333 words) [view diff] exact match in snippet view article find links to article

This allows assessment of other key loci in glial tumors, such as EGFR and TP53 copy number status.[citation needed] Whereas the prognostic relevance of

CKS2 (593 words) [view diff] exact match in snippet view article find links to article

Bertheau P, Turpin E, Rickman DS, et al. (2007). "Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide

PALB2 (1,567 words) [view diff] exact match in snippet view article find links to article

PMID 28594745. S2CID 28223281. Song CV, Teo SH, Taib NA, Yip CH (2018). "BRCA, TP53 and PALB2: a literature review". ecancermedicalscience. 12: 863. doi:10.3332/ecancer

Oxoguanine glycosylase (2,686 words) [view diff] exact match in snippet view article find links to article

Oki E, Oda Y (June 2016). "Reduced MUTYH, MTH1, and OGG1 expression and TP53 mutation in diffuse-type adenocarcinoma of gastric cardia". Human Pathology

PPP1R13B (659 words) [view diff] exact match in snippet view article find links to article

Román-Gómez J, Jiménez-Velasco A, et al. (2006). "ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic

Oligodendroglioma (2,901 words) [view diff] exact match in snippet view article find links to article

This allows assessment of other key loci in glial tumors, such as EGFR and TP53 copy number status. Whereas the prognostic relevance of 1p and 19q deletions

COP9 signalosome complex subunit 3 (1,000 words) [view diff] exact match in snippet view article find links to article

"Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation". Oncogene. 22 (34): 5358–61. doi:10

Medulloblastoma (3,455 words) [view diff] exact match in snippet view article find links to article

(22): 6202–5. PMID 1933879. Eibl RH, Schneemann M (February 2023). "From TP53 Mutations to Molecular Classification and Liquid Biopsy". Biology. 12 (2):

Barrett's esophagus (4,303 words) [view diff] exact match in snippet view article find links to article

CC, Sanchez CA, Odze RD, et al. (February 2007). "NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma". PLOS

Blastic plasmacytoid dendritic cell neoplasm (2,609 words) [view diff] exact match in snippet view article find links to article

abnormalities are associated with the disease: 1) mutations in NRAS, ASXL1, and TP53; 2) deletions of the CDKN2A-ARF-CDKN2B locus on the short arm of chromosome

NEK6 (1,164 words) [view diff] exact match in snippet view article find links to article

results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence. NEK6 has been shown to interact with NEK9

Ribonucleotide reductase (3,493 words) [view diff] exact match in snippet view article find links to article

ribonucleotide reductase M2 B (TP53 inducible) Identifiers Symbol RRM2B NCBI gene 50484 HGNC 17296 OMIM 604712 RefSeq NM_015713 UniProt Q9NTD8 Other data

Mantle cell lymphoma (4,549 words) [view diff] exact match in snippet view article find links to article

"Progressive leukemic non-nodal mantle cell lymphoma associated with deletions of TP53, ATM, and/or 13q14". Annals of Diagnostic Pathology. 18 (4): 214–219. doi:10

Stephen Chanock (867 words) [view diff] exact match in snippet view article find links to article

(2015-07-01). "Further Confirmation of Germline Glioma Risk Variant rs78378222 in TP53 and Its Implication in Tumor Tissues via Integrative Analysis of TCGA Data"

Warburg effect (oncology) (3,046 words) [view diff] exact match in snippet view article

glycolytic enzymes, including the M2 splice isoform of pyruvate kinase. TP53 mutation hits energy metabolism and increases glycolysis in breast cancer

BCLAF1 (796 words) [view diff] exact match in snippet view article find links to article

Miki Y, Yoshida K (2007). "Protein Kinase C δ Induces Transcription of the TP53 Tumor Suppressor Gene by Controlling Death-Promoting Factor Btf in the Apoptotic

C20orf27 (3,092 words) [view diff] exact match in snippet view article find links to article

facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation

Genetic testing (6,424 words) [view diff] exact match in snippet view article find links to article

cancer. Li-Fraumeni syndrome is caused by a gene alteration on the gene TP53. Cancer types associated with a mutation on this gene include breast cancer

PHLDA2 (943 words) [view diff] exact match in snippet view article find links to article

Bertheau P, Turpin E, Rickman DS, et al. (2007). "Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin−Cyclophosphamide

Glycolysis (8,782 words) [view diff] exact match in snippet view article find links to article

107–120. doi:10.1016/j.cell.2006.05.036. PMID 16839880. S2CID 15006256. "TIGAR TP53 induced glycolysis regulatory phosphatase [Homo sapiens (human)] - Gene -

Mary-Claire King (5,047 words) [view diff] exact match in snippet view article find links to article

among Palestinian women: Genetic heterogeneity and a founder mutation in TP53". International Journal of Cancer. 141 (4): 750–756. doi:10.1002/ijc.30771

Stomach cancer (8,142 words) [view diff] exact match in snippet view article find links to article

A, Makishev A, et al. (November 2020). "Association of polymorphisms in TP53 and the promoter region of IL10 with gastric cancer in a Kazakh population"

Anaplastic large-cell lymphoma (5,218 words) [view diff] exact match in snippet view article find links to article

gene in 64% of cases and reports of mutations in JAK1, JAK3, DNMT3A, and TP53 genes. The development of BIA-ALCL, it has often been suggested, may be at

C11orf53 (473 words) [view diff] exact match in snippet view article find links to article

SE, Nikolova O, Liu T, Jones CL, D'Alessandro A, et al. (July 2019). "The TP53 Apoptotic Network Is a Primary Mediator of Resistance to BCL2 Inhibition

Mouse Models of Human Cancer database (1,005 words) [view diff] exact match in snippet view article find links to article

a search for PDX models whose engrafted tumors have amplified KRAS, the TP53 A159V mutation, a deletion of the ALB gene, and high KIT expression. MMHCdb

Methylated-DNA-protein-cysteine methyltransferase (3,856 words) [view diff] exact match in snippet view article find links to article

and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma". Med. Oncol. 31 (2):

Breast cancer classification (9,503 words) [view diff] exact match in snippet view article find links to article

mutations PI3KCA MAPK3K1 GATA3 CCDN1 amplification Similar to luminal A but: TP53 inactivation Rb inactivation Myc-related transcription FOXM1-related transcription

T-cell acute lymphoblastic leukemia (2,695 words) [view diff] exact match in snippet view article find links to article

Li–Fraumeni syndrome is an inherited condition that leads to mutation of TP53, a tumor suppressor gene, which then increases risk of T-ALL. Mutation in

Gelareh Zadeh (755 words) [view diff] exact match in snippet view article find links to article

of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations". Acta Neuropathologica. 124 (5): 615–625. doi:10.1007/S00401-012-1031-3

Childhood cancer (5,812 words) [view diff] exact match in snippet view article find links to article

(4-7). Identified Cancer Predisposition Syndromes Li-Fraumeni syndrome (TP53) Hereditary breast or ovarian cancer (BRCA 1⁄2) Colorectal cancer/polyposis

Genetic counseling (10,244 words) [view diff] exact match in snippet view article find links to article

Margison GP, Forster G, et al. (October 1999). "Are there low-penetrance TP53 Alleles? evidence from childhood adrenocortical tumors". American Journal

Christopher Hourigan (1,128 words) [view diff] exact match in snippet view article find links to article

intervention in patients with AML MRD may improve survival, that low-level TP53 mutations are detectable pre-transplantation in patients with sickle cell

Nemtabrutinib (501 words) [view diff] exact match in snippet view article find links to article

chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) without TP53 aberrations". Journal of Clinical Oncology. 41 (16_suppl): TPS7594. doi:10

Albert J. Fornace Jr. (1,021 words) [view diff] exact match in snippet view article find links to article

made important contributions in the characterization of pathways (such as TP53) involved in these critical cellular processes. He has been a pioneer in

FAM43A (1,640 words) [view diff] exact match in snippet view article find links to article

apoptosis by up-regulating cyclin-D1 expression through the suppression of p53/TP53 phosphorylation. Protein phosphatase 2A is one of the four major Ser/Thr

Dental follicle (3,475 words) [view diff] exact match in snippet view article find links to article

transcriptomics identified regulated transcription factors such as SP1 and TP53. These transcription factors were more precisely identified by bioinformatics

Nitzan Rosenfeld (981 words) [view diff] exact match in snippet view article find links to article

Wendi (2016-12-20). Mardis, Elaine Rene (ed.). "Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for

Jórunn Erla Eyfjörð (2,034 words) [view diff] exact match in snippet view article find links to article

tumors was shown to be associated with mutations in the tumor suppressor gene TP53. After the discovery of the Icelandic BRCA2 founder mutation Jórunn and her

PLAC1 (3,873 words) [view diff] case mismatch in snippet view article find links to article

Chen Y, Schlessinger D, Nagaraja R 2013 T antigen transformation reveals Tp53/RB-dependent route to PLAC1 transcription activation in primary fibroblasts

Epigenetics and melanoma (2,898 words) [view diff] exact match in snippet view article find links to article

PIK3CA Mutation <5 AKT3 Amplification 40- 60 Tumor Suppressor Genes INK4A Mutation 40- 87 ARF Mutation 40- 70 PTEN Mutation 5- 40 TP53 Mutation 0- 25

List of minor planets: 84001–85000 (274 words) [view diff] exact match in snippet view article find links to article

2002 TF53 — October 2, 2002 Socorro LINEAR · 6.0 km MPC · JPL 84334 2002 TP53 — October 2, 2002 Socorro LINEAR · 7.8 km MPC · JPL 84335 2002 TR53 — October

Radiomics (5,585 words) [view diff] exact match in snippet view article find links to article

mutations of glioblastoma (GBM), such as 1p/19q deletion, MGMT methylation, TP53, EGFR, and NF1, have been shown to be significantly predicted by magnetic

Mir-25 microRNA precursor family (2,418 words) [view diff] exact match in snippet view article find links to article

Alder H, Kaur B, Aqeilan RI, Pichiorri F, Croce CM (April 2012). "MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme". Proceedings of the National

Circulating tumor DNA (5,856 words) [view diff] exact match in snippet view article find links to article

technique was shown to successfully identify mutations scattered in the TP53 tumor suppressor gene in advanced ovarian cancer patients. The sensitivity

2017 in science (18,502 words) [view diff] exact match in snippet view article find links to article

Rochester Medical Center identify four genes – KRAS, CDKN2A, SMAD4, and TP53 – responsible for how long patients survive with pancreatic cancer. Researchers

Kári Stefánsson (12,459 words) [view diff] exact match in snippet view article find links to article

harboring risk variants for many types of cancer, and variants in the TERT, TP53 and LG24 genes as risk factors for multiple cancers. deCODE has discovered

List of minor planets: 216001–217000 (274 words) [view diff] exact match in snippet view article find links to article

— October 12, 2006 Kitt Peak Spacewatch · 3.1 km MPC · JPL 216183 2006 TP53 — October 12, 2006 Kitt Peak Spacewatch · 2.9 km MPC · JPL 216184 2006 TT60

List of minor planets: 300001–301000 (274 words) [view diff] exact match in snippet view article find links to article

— October 4, 2007 Kitt Peak Spacewatch MIS 2.2 km MPC · JPL 300445 2007 TP53 — October 4, 2007 Kitt Peak Spacewatch · 1.6 km MPC · JPL 300446 2007 TK54

List of minor planets: 469001–470000 (274 words) [view diff] exact match in snippet view article find links to article

2000 TF8 — October 1, 2000 Socorro LINEAR (5) 650 m MPC · JPL 469345 2000 TP53 — October 1, 2000 Socorro LINEAR · 2.8 km MPC · JPL 469346 2000 TN64 — October

List of minor planets: 156001–157000 (274 words) [view diff] exact match in snippet view article find links to article

2001 TP44 — October 14, 2001 Socorro LINEAR · 2.4 km MPC · JPL 156141 2001 TP53 — October 13, 2001 Socorro LINEAR V 940 m MPC · JPL 156142 2001 TB61 — October

CCDC190 (2,085 words) [view diff] exact match in snippet view article find links to article

histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. PPIB peptidylprolyl isomerase B crosslinking mass spectrometry BioGRID

SEE-FIM Protocol (1,934 words) [view diff] exact match in snippet view article find links to article

loss of a BRCA gene imposes an increased risk of breast and ovarian cancer. TP53 – A tumor suppressor gene that is mutated in High grade serous carcinoma

List of minor planets: 378001–379000 (274 words) [view diff] exact match in snippet view article find links to article

TK51 — October 2, 2008 Kitt Peak Spacewatch · 1.9 km MPC · JPL 378855 2008 TP53 — March 26, 2006 Mount Lemmon Mount Lemmon Survey CHA 1.9 km MPC · JPL 378856

List of minor planets: 388001–389000 (274 words) [view diff] exact match in snippet view article find links to article

October 7, 2005 Andrushivka Andrushivka Obs. · 960 m MPC · JPL 388058 2005 TP53 — October 1, 2005 Catalina CSS LIX 4.4 km MPC · JPL 388059 2005 TA64 — October

CUX1 (4,649 words) [view diff] exact match in snippet view article find links to article

N, Rice G, Quinn M, Baker M, and Campbell I. "Mutation analysis of CDP, TP53, and KRAS in uterine leiomyomas". Molecular Carcinogenesis 2003, 37:61–4

Zinc finger protein 226 (3,870 words) [view diff] exact match in snippet view article find links to article

in PB-EPCs when compared to CB-EPCs. PB-EPCs have more tumor suppressor (TP53) expression when compared to CB-EPCs. CB-EPCs have more angiogenic expression

List of minor planets: 415001–416000 (274 words) [view diff] exact match in snippet view article find links to article

11, 2005 Mount Lemmon Mount Lemmon Survey · 3.5 km MPC · JPL 415451 2013 TP53 — May 9, 2002 Kitt Peak Spacewatch · 2.9 km MPC · JPL 415452 2013 TP65 —

List of minor planets: 557001–558000 (274 words) [view diff] exact match in snippet view article find links to article

September 14, 2014 Kitt Peak Spacewatch · 1.4 km MPC · JPL 557176 2014 TP53 — September 18, 2003 Palomar NEAT · 750 m MPC · JPL 557177 2014 TZ53 — November

List of human transcription factors (81 words) [view diff] exact match in snippet view article find links to article

ENSG00000197579 Unknown Known motif – In vivo/Misc source [979] TCCCAGCTACTTTGGGA TP53 ENSG00000141510 p53 Known motif – In vivo/Misc source [980] DRCATGYYBRGRCATGYCY

List of minor planets: 669001–670000 (274 words) [view diff] exact match in snippet view article find links to article

September 27, 2003 Kitt Peak Spacewatch · 1.5 km MPC · JPL 669119 2012 TP53 — April 3, 2011 Haleakala Pan-STARRS · 1.5 km MPC · JPL 669120 2012 TR54