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searching for PALB2 14 found (42 total)

alternate case: pALB2

Bing Xia (694 words) [view diff] exact match in snippet view article find links to article

he directs the Xia Laboratory. He is best known for his discovery of the PALB2 tumor suppressor gene, a notable scientific advance in the field of cancer
Genetic heterogeneity (1,248 words) [view diff] exact match in snippet view article find links to article
rare cancer syndromes. Mutations in CHECK2, ATM, NBS1, RAD50, BRIP1, and PALB2 can double the risk of breast cancer development. Biallelic mutations, in
FANCL (1,374 words) [view diff] exact match in snippet view article find links to article
1182/blood-2002-01-0278. PMID 12239151. Park JY, Zhang F, Andreassen PR (2014). "PALB2: the hub of a network of tumor suppressors involved in DNA damage responses"
Fanconi anemia (4,140 words) [view diff] exact match in snippet view article find links to article
FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, FANCN (PALB2), FANCO (RAD51C), FANCP (SLX4), FANCQ (XPF), FANCS (BRCA1), FANCT (UBE2T)
Mouse avatars (637 words) [view diff] exact match in snippet view article find links to article
al: Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer
University of Medicine and Dentistry of New Jersey (2,163 words) [view diff] exact match in snippet view article find links to article
Rutgers Cancer Institute of New Jersey, known for his discovery of the PALB2 tumor suppressor gene Marilyn Kozak, RWJMS Professor of Biochemistry, discoverer
Shapiro–Senapathy algorithm (6,804 words) [view diff] exact match in snippet view article find links to article
different splice sites in various genes causing breast cancer (e.g., BRCA1, PALB2), ovarian cancer (e.g., SLC9A3R1, COL7A1, HSD17B7), colon cancer (e.g.,
Protein-truncating variants (590 words) [view diff] exact match in snippet view article find links to article
Shahana (2017-11-01). "Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks". Journal
CHEK2 (2,797 words) [view diff] exact match in snippet view article find links to article
A, et al. (August 2019). "Pathogenic and likely pathogenic variants in PALB2, CHEK2, and other known breast cancer susceptibility genes among 1054 BRCA-negative
Enhancer of polycomb homolog 2 (drosophila) (516 words) [view diff] exact match in snippet view article
Shinmyozu K, Nakayama J, Andreassen PR (April 2010). "MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks". Journal
Kelly Metcalfe (962 words) [view diff] exact match in snippet view article find links to article
another grant to fund her study, Breast cancer treatment in women with PALB2 mutations. In 2018, Metcalfe was appointed Acting Associate Dean, Research
Bert Vogelstein (3,823 words) [view diff] exact match in snippet view article find links to article
Hruban RH, Kamiyama M, et al. (April 2009). "Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene". Science. 324 (5924): 217. Bibcode:2009Sci
Talazoparib (1,214 words) [view diff] exact match in snippet view article find links to article
genes (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) were assessed prospectively using tumor tissue and/or circulating
Double-strand break repair model (4,127 words) [view diff] exact match in snippet view article find links to article
phosphorylates BRCA1. Ubiquinated FANCD2 complexes with BRCA1 and RAD51. The PALB2 protein acts as a hub, bringing together BRCA1, BRCA2 and RAD51 at the site