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searching for Autophagosome 145 found (183 total)

ATG3 (591 words) [view diff] exact match in snippet view article find links to article

subunit of the autophagosome complex. The small C-terminal domain is likely to be a distinct binding region for the stability of the autophagosome complex.

ATG8 (2,085 words) [view diff] exact match in snippet view article find links to article

sequester portions of the cytosol, the so-called autophagosomes. The outer membrane of these autophagosomes subsequently fuses with the lysosome/vacuole to

ATG7 (978 words) [view diff] exact match in snippet view article find links to article

these autophagy-specific UBL systems makes it an essential regulator of autophagosome assembly. Homologous to the ATP-binding and catalytic sites of E1 activator

SNAP29 (1,108 words) [view diff] exact match in snippet view article find links to article

autophagosome membrane SNARE complex ciliary membrane ciliary pocket membrane cytoplasmic vesicle presynapse Golgi membrane nucleoplasm autophagosome

STX17 (409 words) [view diff] exact match in snippet view article find links to article

(2012). "The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes". Cell. 151 (6): 1256–69. doi:10

ATP13A2 (712 words) [view diff] exact match in snippet view article find links to article

integral component of lysosomal membrane multivesicular body membrane autophagosome late endosome neuronal cell body lysosomal membrane Biological process

David C. Rubinsztein (1,277 words) [view diff] exact match in snippet view article find links to article

identifying the plasma membrane as a source of autophagosome membrane and characterising early events in autophagosome biogenesis,. Furthermore, he studied how

RAB23 (800 words) [view diff] exact match in snippet view article find links to article

cytoplasm endosome phagocytic vesicle membrane membrane plasma membrane autophagosome phagocytic vesicle endosome membrane cytoplasmic vesicle centrosome

GABARAP (1,678 words) [view diff] exact match in snippet view article find links to article

GABARAP has an important function in autophagosome mediated autophagy, since it is crucial for autophagosome formation and sequestration of cytosolic

NCOA4 (1,632 words) [view diff] exact match in snippet view article find links to article

ferritin heavy chain and latching on to ATG8 on the surface of the autophagosome. NCOA4 has been shown to interact with: Androgen receptor, and Peroxisome

Chaperone-assisted selective autophagy (1,144 words) [view diff] exact match in snippet view article find links to article

chaperone-associated ubiquitin ligases. The ubiquitinated proteins are enclosed in autophagosomes, which eventually fuse with lysosomes, leading to the degradation of

MAP1LC3A (1,150 words) [view diff] exact match in snippet view article find links to article

2008). "The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes". J. Cell Sci. 121 (Pt 16): 2685–95. doi:10.1242/jcs.026005. PMID 18653543

Autophagy protein 5 (2,808 words) [view diff] exact match in snippet view article find links to article

becoming LC3-II. After formation of the autophagosome, the ATG12-ATG5:ATG16L complex dissociates from the autophagosome. In instances of spontaneous apoptosis

ULK1 (1,926 words) [view diff] exact match in snippet view article find links to article

It is part of the ULK1-complex, which is needed in early steps of autophagosome biogenesis. The ULK1 complex also consists of the FAK family kinase

BECN1 (1,482 words) [view diff] exact match in snippet view article find links to article

mitochondrial membranes trans-Golgi network Golgi apparatus cytosol nucleus autophagosome phagophore assembly site membrane dendrite endoplasmic reticulum phosphatidylinositol

UVRAG (685 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region protein-containing complex autophagosome membrane autophagosome cytoplasmic vesicle Biological process double-strand break

WIPI2 (783 words) [view diff] exact match in snippet view article find links to article

diverse range of pathogens. WIPI2 is recruited early to the forming autophagosome, along with DFCP-1, ULK-1 and Atg16, where it positively regulates the

ATG9A (569 words) [view diff] exact match in snippet view article find links to article

(December 2020). "Structure, lipid scrambling activity and role in autophagosome formation of ATG9A". Nature Structural & Molecular Biology. 27 (12):

ATG12 (847 words) [view diff] exact match in snippet view article find links to article

including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the

LAMP2 (2,103 words) [view diff] exact match in snippet view article find links to article

dense granule membrane lysosome endosome membrane extracellular exosome autophagosome membrane extracellular space trans-Golgi network cytoplasmic vesicle

CALCOCO2 (686 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm perinuclear region of cytoplasm autophagosome autophagosome membrane cytoskeleton membrane cytoplasmic vesicle nucleus intracellular

GABARAPL2 (1,114 words) [view diff] exact match in snippet view article find links to article

apparatus Golgi membrane intracellular anatomical structure autophagosome autophagosome membrane cytoplasmic vesicle cytosol Biological process positive

UBQLN1 (1,428 words) [view diff] exact match in snippet view article find links to article

receptor 3 signaling pathway cellular response to hypoxia autophagosome maturation autophagosome assembly macroautophagy ubiquitin-dependent protein catabolic

IRGM (1,079 words) [view diff] exact match in snippet view article find links to article

binding GTPase activity Cellular component phagocytic vesicle membrane autophagosome membrane cell projection phagocytic cup plasma membrane membrane cytoplasmic

UBQLN2 (1,042 words) [view diff] exact match in snippet view article find links to article

cytoplasm autophagosome plasma membrane cytoplasmic vesicle nucleus membrane cytosol Biological process autophagy regulation of autophagosome assembly

Battenin (1,268 words) [view diff] exact match in snippet view article find links to article

apparatus membrane synaptic vesicle Golgi membrane plasma membrane autophagosome lysosomal membrane integral component of endoplasmic reticulum membrane

Ubiquilin 4 (266 words) [view diff] exact match in snippet view article find links to article

binding Cellular component cytoplasm perinuclear region of cytoplasm autophagosome nuclear proteasome complex cytosolic proteasome complex cytosol endoplasmic

TANK-binding kinase 1 (2,296 words) [view diff] exact match in snippet view article find links to article

"TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation". Immunity. 37 (2): 223–234. doi:10.1016/j.immuni.2012.04

TP53INP1 (653 words) [view diff] exact match in snippet view article find links to article

antioxidant activity protein binding Cellular component cytosol PML body autophagosome cytoplasmic vesicle nucleus nucleoplasm cytoplasm Biological process

PIP4K2C (117 words) [view diff] exact match in snippet view article find links to article

membrane autophagosome extracellular exosome Biological process phosphatidylinositol metabolic process positive regulation of autophagosome assembly phosphorylation

PIK3C3 (901 words) [view diff] exact match in snippet view article find links to article

membrane membrane phosphatidylinositol 3-kinase complex, class III autophagosome midbody phagocytic vesicle axoneme cytoplasmic vesicle autolysosome

RAB33B (462 words) [view diff] exact match in snippet view article find links to article

morphogenesis autophagy regulation of cell growth autophagosome assembly regulation of autophagosome assembly protein localization to Golgi apparatus intracellular

VPS33B (568 words) [view diff] exact match in snippet view article find links to article

localization endosome organization vesicle docking involved in exocytosis autophagosome maturation lysosome localization transport protein transport vesicle-mediated

WDFY3 (651 words) [view diff] exact match in snippet view article find links to article

envelope extrinsic component of membrane extrinsic component of autophagosome membrane autophagosome cytoplasm inclusion body membrane nucleus nucleolus plasma

RB1CC1 (1,051 words) [view diff] exact match in snippet view article find links to article

Mizushima N (May 2008). "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells". The Journal of Cell Biology. 181 (3):

Gaba type a receptor associated protein like 1 (611 words) [view diff] exact match in snippet view article find links to article

cytoplasmic vesicle autophagosome membrane cytosol Biological process autophagy macroautophagy autophagosome maturation autophagosome assembly autophagy

RB1CC1 (1,051 words) [view diff] exact match in snippet view article find links to article

Mizushima N (May 2008). "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells". The Journal of Cell Biology. 181 (3):

TBC1D12 (119 words) [view diff] exact match in snippet view article find links to article

component autophagosome recycling endosome intracellular anatomical structure Biological process regulation of vesicle fusion regulation of autophagosome assembly

VPS33A (560 words) [view diff] exact match in snippet view article find links to article

region of cytoplasm lysosome cytoplasmic vesicle clathrin-coated vesicle autophagosome Biological process endosome to lysosome transport platelet formation

ML-SI3 (383 words) [view diff] exact match in snippet view article find links to article

Ballabio A, Medina DL (December 2019). "TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway". Nature

MTMR3 (280 words) [view diff] exact match in snippet view article find links to article

starvation lipid metabolism protein dephosphorylation regulation of autophagosome assembly phosphatidylinositol dephosphorylation phosphatidylinositol

VMP1 (509 words) [view diff] exact match in snippet view article find links to article

vacuolar membrane integral component of membrane vacuole plasma membrane autophagosome membrane nucleolus endoplasmic reticulum membrane phagophore assembly

ATG4B (1,285 words) [view diff] exact match in snippet view article find links to article

structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers". Journal of Molecular Biology. 355 (4): 612–8. doi:10

Rab (G-protein) (1,327 words) [view diff] exact match in snippet view article

Survival in Alveolar Macrophages as a Result of Coronin-1a Inhibition of Autophagosome Formation", Autophagy: Cancer, Other Pathologies, Inflammation, Immunity

RAB7A (2,315 words) [view diff] exact match in snippet view article find links to article

lipid droplet melanosome membrane retromer complex lysosomal membrane autophagosome membrane phagocytic vesicle lysosome extracellular exosome cytoplasmic

PIP4K2A (1,048 words) [view diff] exact match in snippet view article find links to article

binding Cellular component cytoplasm cytosol membrane plasma membrane autophagosome nucleus nucleoplasm Biological process megakaryocyte development phosphatidylinositol

KIAA1012 (437 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum to Golgi vesicle-mediated transport vesicle-mediated transport Golgi organization autophagosome assembly Sources:Amigo / QuickGO

CLEC16A (1,635 words) [view diff] exact match in snippet view article find links to article

component of membrane Biological process autophagy positive regulation of autophagosome maturation negative regulation of proteasomal ubiquitin-dependent protein

STX12 (779 words) [view diff] exact match in snippet view article find links to article

postsynaptic recycling endosome Biological process protein stabilization autophagosome assembly vesicle docking cholesterol efflux protein transport intracellular

PIP4K2B (775 words) [view diff] exact match in snippet view article find links to article

cytoplasm cytosol endoplasmic reticulum membrane membrane plasma membrane autophagosome endoplasmic reticulum nucleus nucleoplasm Biological process phosphatidylinositol

Myotubularin 1 (887 words) [view diff] exact match in snippet view article find links to article

membrane cytosol sarcomere Biological process negative regulation of autophagosome assembly negative regulation of protein kinase B signaling muscle cell

Tectonin beta-propeller repeat containing 1 (125 words) [view diff] exact match in snippet view article find links to article

Cellular component integral component of membrane lysosomal membrane autophagosome membrane lysosome cytoplasmic vesicle membrane nucleoplasm intracellular

Ectonucleoside triphosphate diphosphohydrolase 4 (344 words) [view diff] exact match in snippet view article find links to article

membrane Golgi apparatus autophagosome membrane integral component of membrane Golgi membrane integral component of autophagosome membrane Biological process

DAPK2 (700 words) [view diff] exact match in snippet view article find links to article

identical protein binding ATP binding Cellular component cytoplasm autophagosome lumen cytoplasmic vesicle Golgi apparatus intracellular membrane-bounded

MAPK15 (1,095 words) [view diff] exact match in snippet view article find links to article

intracellular anatomical structure extracellular region nucleus cytoplasm autophagosome centriole cell-cell junction axoneme ciliary basal body Golgi apparatus

Vici syndrome (1,428 words) [view diff] exact match in snippet view article find links to article

interfere with the autophagy. This appears to be due to a block in the autophagosome-lysosome fusion mechanism. The diagnostic workup usually includes an

SH3GLB1 (1,263 words) [view diff] exact match in snippet view article find links to article

Golgi apparatus membrane Golgi membrane mitochondrial outer membrane autophagosome membrane midbody mitochondrion extracellular exosome cytoplasmic vesicle

Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article

apparatus membrane plasma membrane integral component of plasma membrane autophagosome membrane cytoplasm trans-Golgi network cytosol Biological process negative

MCOLN1 (480 words) [view diff] exact match in snippet view article find links to article

cytosol ion transport cation transport iron ion transmembrane transport autophagosome maturation calcium ion transmembrane transport transport adaptive immune

SMURF1 (1,916 words) [view diff] exact match in snippet view article find links to article

exosome Biological process cell differentiation engulfment of target by autophagosome ectoderm development protein polyubiquitination BMP signaling pathway

Vesicle-associated membrane protein 8 (1,368 words) [view diff] exact match in snippet view article find links to article

Biological process post-Golgi vesicle-mediated transport autophagy autophagosome maturation negative regulation of secretion by cell protein transport

NPRL2 (418 words) [view diff] exact match in snippet view article find links to article

phosphorylation cellular response to nitrogen starvation positive regulation of autophagy regulation of autophagosome assembly Sources:Amigo / QuickGO

MCOLN3 (818 words) [view diff] exact match in snippet view article find links to article

component plasma membrane membrane cytoplasm integral component of membrane autophagosome membrane lysosome lysosomal membrane endosome cytoplasmic vesicle early

Yoshinori Ohsumi (1,449 words) [view diff] exact match in snippet view article find links to article

"Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization". Journal of Cell Biology. 124 (6): 903–913

NRBF2 (508 words) [view diff] exact match in snippet view article find links to article

component cytoplasm phosphatidylinositol 3-kinase complex, class III autophagosome nucleus nucleoplasm cytoplasmic vesicle Biological process transcription

VIPAS39 (451 words) [view diff] exact match in snippet view article find links to article

apparatus Biological process protein transport cell differentiation autophagosome maturation regulation of transcription, DNA-templated transcription

C9orf72 (3,424 words) [view diff] exact match in snippet view article find links to article

binding guanyl-nucleotide exchange factor activity Cellular component autophagosome extracellular region endosome lysosome cytoplasmic vesicle nucleus extracellular

ATG4D (323 words) [view diff] exact match in snippet view article find links to article

of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes

RAB3GAP2 (584 words) [view diff] exact match in snippet view article find links to article

reticulum membrane intracellular protein transport positive regulation of autophagosome assembly positive regulation of endoplasmic reticulum tubular network

VPS18 (623 words) [view diff] exact match in snippet view article find links to article

adaptor complex endosome late endosome membrane late endosome membrane autophagosome lysosomal membrane early endosome actin filament CORVET complex lysosome

TICAM1 (616 words) [view diff] exact match in snippet view article find links to article

binding protein kinase binding Cellular component cytosol ripoptosome autophagosome endosome membrane cytoplasmic vesicle Biological process response to

FEZ2 (562 words) [view diff] exact match in snippet view article find links to article

Biological process signal transduction nervous system development negative regulation of autophagosome assembly axon guidance Sources:Amigo / QuickGO

RAB33A (437 words) [view diff] exact match in snippet view article find links to article

membrane endoplasmic reticulum membrane Biological process regulation of autophagosome assembly antigen processing and presentation intracellular protein transport

Glucocerebrosidase (2,001 words) [view diff] exact match in snippet view article find links to article

autophagy of mitochondrion in response to mitochondrial depolarization autophagosome organization regulation of lysosomal protein catabolic process beta-glucoside

VPS11 (637 words) [view diff] exact match in snippet view article find links to article

endosome late endosome late endosome membrane membrane endocytic vesicle autophagosome lysosomal membrane early endosome lysosome cytoplasmic vesicle clathrin-coated

Urapidil (673 words) [view diff] exact match in snippet view article find links to article

has the ability to counteract autophagy by lowering the quantity of autophagosome marker LC3B and caspase-3 which also plays a critical role in autophagy

CHMP4B (713 words) [view diff] exact match in snippet view article find links to article

nuclear envelope nucleus Biological process negative regulation of autophagosome assembly regulation of centrosome duplication viral life cycle nucleus

CHMP4A (665 words) [view diff] exact match in snippet view article find links to article

cytoplasmic vesicle nucleus Biological process negative regulation of autophagosome assembly protein polymerization viral life cycle nucleus organization

WDR45 (697 words) [view diff] exact match in snippet view article find links to article

protein localization to phagophore assembly site autophagy of nucleus autophagosome assembly cellular response to starvation Sources:Amigo / QuickGO

Ghanshyam Swarup (1,049 words) [view diff] exact match in snippet view article find links to article

Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation

Jae U. Jung (383 words) [view diff] exact match in snippet view article find links to article

"Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking". Nat Cell Biol. 10 (7): 776–87

USP33 (682 words) [view diff] exact match in snippet view article find links to article

VCB complex focal adhesion nucleoplasm microtubule organizing center autophagosome perinuclear region of cytoplasm cytoskeleton cytosol Biological process

SEC22B (741 words) [view diff] exact match in snippet view article find links to article

fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane negative regulation of autophagosome assembly Sources:Amigo / QuickGO

IFT88 (850 words) [view diff] exact match in snippet view article find links to article

center Biological process regulation of cilium assembly regulation of autophagosome assembly cilium assembly cell projection organization intraciliary transport

TOLLIP (1,271 words) [view diff] exact match in snippet view article find links to article

communications , Tollip can contribute to the fusion of endo-lysosome and autophagosome. Mice with Tollip deletion exhibit elevated risks for inflammatory diseases

MEFV (1,218 words) [view diff] exact match in snippet view article find links to article

ruffle intracellular anatomical structure microtubule associated complex autophagosome microtubule cytoskeleton cytoplasmic vesicle nucleus lamellipodium Biological

ZFYVE1 (579 words) [view diff] exact match in snippet view article find links to article

4-bisphosphate binding Cellular component perinuclear region of cytoplasm autophagosome mitochondria-associated endoplasmic reticulum membrane Golgi stack Golgi

WDR45L (272 words) [view diff] exact match in snippet view article find links to article

phagophore assembly site autophagy of mitochondrion autophagy of nucleus autophagosome assembly cellular response to starvation autophagy Sources:Amigo / QuickGO

SCFD1 (726 words) [view diff] exact match in snippet view article find links to article

membrane endoplasmic reticulum Biological process negative regulation of autophagosome assembly regulation of ER to Golgi vesicle-mediated transport response

Cysteine protease ATG4A (460 words) [view diff] exact match in snippet view article find links to article

protein lipidation protein delipidation autophagy of mitochondrion autophagosome assembly proteolysis protein targeting to membrane Sources:Amigo / QuickGO

RAB1B (893 words) [view diff] exact match in snippet view article find links to article

regulation of glycoprotein metabolic process autophagy regulation of autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport COPII

NUPR1 (868 words) [view diff] exact match in snippet view article find links to article

positive regulation of neuroinflammatory response negative regulation of autophagosome assembly positive regulation of oxidative phosphorylation negative regulation

RAB5A (1,473 words) [view diff] exact match in snippet view article find links to article

internalization involved in canonical Wnt signaling pathway regulation of autophagosome assembly synaptic vesicle recycling early endosome to late endosome

RAB3GAP1 (939 words) [view diff] exact match in snippet view article find links to article

protein-containing complex Biological process positive regulation of autophagosome assembly lipid droplet organization regulation of GTPase activity positive

RNF5 (907 words) [view diff] exact match in snippet view article find links to article

ubiquitination ER-associated misfolded protein catabolic process regulation of autophagosome assembly protein K48-linked ubiquitination protein destabilization protein

VTI1A (574 words) [view diff] exact match in snippet view article find links to article

component of membrane endosome Golgi apparatus membrane synaptic vesicle autophagosome neuronal cell body SNARE complex perinuclear region of cytoplasm neuron

RNF103-CHMP3 readthrough (109 words) [view diff] exact match in snippet view article find links to article

endosome cytoplasmic vesicle multivesicular body Biological process autophagosome maturation viral life cycle protein polymerization multivesicular body

SRPX (569 words) [view diff] exact match in snippet view article find links to article

binding extracellular matrix structural constituent Cellular component autophagosome cell surface endoplasmic reticulum membrane collagen-containing extracellular

PIK3C2B (1,114 words) [view diff] exact match in snippet view article find links to article

to starvation phosphatidylinositol-3-phosphate biosynthetic process autophagosome organization macroautophagy phosphatidylinositol 3-kinase signaling

Optineurin (1,202 words) [view diff] exact match in snippet view article find links to article

Cellular component recycling endosome endosome Golgi membrane nucleoplasm autophagosome trans-Golgi network perinuclear region of cytoplasm nucleus Golgi apparatus

TRIM21 (1,478 words) [view diff] exact match in snippet view article find links to article

ubiquitin ligase complex P-body intracellular anatomical structure autophagosome cytoplasmic vesicle nucleus nucleoplasm ribonucleoprotein complex Biological

Beta-2 adrenergic receptor (3,372 words) [view diff] exact match in snippet view article find links to article

clathrin-coated vesicle membrane Biological process positive regulation of autophagosome maturation adenylate cyclase-activating G protein-coupled receptor signaling

NPRL3 (648 words) [view diff] exact match in snippet view article find links to article

cardiac muscle tissue development positive regulation of GTPase activity TORC1 signaling regulation of autophagosome assembly Sources:Amigo / QuickGO

PIK3R4 (565 words) [view diff] exact match in snippet view article find links to article

membrane phosphatidylinositol 3-kinase complex, class III nuclear pore autophagosome phosphatidylinositol 3-kinase complex, class III, type I axoneme nucleus-vacuole

LRSAM1 (1,040 words) [view diff] exact match in snippet view article find links to article

Biological process negative regulation of endocytosis positive regulation of autophagosome assembly protein polyubiquitination positive regulation of xenophagy

SYNPO2 (1,055 words) [view diff] exact match in snippet view article find links to article

adhesion cell junction actin cytoskeleton Z disc Biological process autophagosome assembly positive regulation of cell migration positive regulation of

FEZ1 (1,052 words) [view diff] exact match in snippet view article find links to article

microtubule cytoskeleton Biological process negative regulation of autophagosome assembly cellular response to growth factor stimulus nervous system

Pacer (protein) (610 words) [view diff] exact match in snippet view article

"Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17". Molecular Cell. 65 (6): 1029–1043.e5

SNAPAP (1,230 words) [view diff] exact match in snippet view article find links to article

zone membrane anterograde axonal transport melanosome organization autophagosome maturation synaptic vesicle transport terminal button organization anterograde

NSFL1C (953 words) [view diff] exact match in snippet view article find links to article

organization proteasome-mediated ubiquitin-dependent protein catabolic process autophagosome assembly regulation of phosphoprotein phosphatase activity establishment

RAB1A (1,403 words) [view diff] exact match in snippet view article find links to article

intestinal barrier Golgi organization vesicle transport along microtubule autophagosome assembly positive regulation of glycoprotein metabolic process autophagy

VTI1B (934 words) [view diff] exact match in snippet view article find links to article

Biological process membrane fusion vesicle docking involved in exocytosis autophagosome maturation protein transport cell population proliferation intracellular

IFT20 (652 words) [view diff] exact match in snippet view article find links to article

regulation of canonical Wnt signaling pathway visual learning regulation of autophagosome assembly regulation of cilium assembly establishment of planar polarity

RPN2 (1,248 words) [view diff] exact match in snippet view article find links to article

component integral component of membrane rough endoplasmic reticulum autophagosome membrane membrane endoplasmic reticulum membrane oligosaccharyltransferase

Presenilin-1 (3,113 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum calcium ion homeostasis response to oxidative stress autophagosome assembly positive regulation of transcription, DNA-templated heart development

Thapsigargin (1,360 words) [view diff] exact match in snippet view article find links to article

(2013-10-25). "Modulation of intracellular calcium homeostasis blocks autophagosome formation". Autophagy. 9 (10): 1475–1490. doi:10.4161/auto.25900. ISSN 1554-8627

Autophagy-related protein 13 (840 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum membrane Biological process autophagy macroautophagy autophagosome assembly positive regulation of protein targeting to mitochondrion mitophagy

NBR1 (864 words) [view diff] exact match in snippet view article find links to article

kinase binding ubiquitin binding Cellular component cytoplasm M band autophagosome cytosol late endosome lysosome extracellular exosome membrane cytoplasmic

Sec14 (983 words) [view diff] exact match in snippet view article find links to article

secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae". Molecular Biology of the Cell

Stimulator of interferon genes (2,748 words) [view diff] exact match in snippet view article find links to article

after double-stranded DNA stimulation, suggesting its presence in the autophagosome. STING mediates the type I interferon production in response to intracellular

LRRK2 (1,929 words) [view diff] exact match in snippet view article find links to article

phosphorylation neuron death GTP metabolic process negative regulation of autophagosome assembly olfactory bulb development cellular response to starvation

Abgent (850 words) [view diff] exact match in snippet view article find links to article

family. Many ARM-containing proteins (ARM-CPs) are also involved in autophagosome formation and maturation and a few of them in regulating signaling pathways

Huntingtin (3,255 words) [view diff] exact match in snippet view article find links to article

binding Cellular component late endosome Golgi apparatus nucleoplasm autophagosome endoplasmic reticulum centriole cytoplasmic vesicle membrane dendrite

Valosin-containing protein (5,866 words) [view diff] exact match in snippet view article find links to article

ones) by engulfing them into double-membrane-surrounded vesicles named autophagosome, but the precise role of VCP in this process is unclear. VCP also functions

Vojo Deretic (3,926 words) [view diff] exact match in snippet view article find links to article

autophagosomes form in mammalian cells, identifying HyPAS (hybrid pre-autophagosomal structure) prophagophores as direct precursors to autophagosomes

TSG101 (2,013 words) [view diff] exact match in snippet view article find links to article

budding keratinocyte differentiation cell division endosomal transport autophagosome maturation regulation of cell growth protein transport ubiquitin-dependent

Autophagy-related protein 101 (840 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum membrane Biological process autophagy macroautophagy autophagosome assembly regulation of macroautophagy Sources:Amigo / QuickGO

VPS24 (1,026 words) [view diff] exact match in snippet view article find links to article

endosome cytoplasmic vesicle multivesicular body Biological process autophagosome maturation viral life cycle protein polymerization multivesicular body

HSPA8 (3,533 words) [view diff] exact match in snippet view article find links to article

space secretory granule lumen ficolin-1-rich granule lumen lysosome autophagosome axon dendrite terminal bouton presynaptic cytosol postsynaptic cytosol

Vesicle-associated membrane protein 7 (1,226 words) [view diff] exact match in snippet view article find links to article

membrane hippocampal mossy fiber to CA3 synapse Biological process autophagosome maturation vesicle transport along microtubule vesicle fusion with Golgi

Reactive oxygen species (8,480 words) [view diff] exact match in snippet view article find links to article

tcb.2007.07.009. PMID 17804237. Xie Z, Klionsky DJ (October 2007). "Autophagosome formation: core machinery and adaptations". Nature Cell Biology. 9 (10):

Dishevelled binding antagonist of beta catenin 1 (964 words) [view diff] exact match in snippet view article find links to article

a Wnt suppressor, or alternately a Wnt-independent regulator of the autophagosome. The Dact1 protein is annotated with 10 intrinsically disordered domains

PEG3 (872 words) [view diff] exact match in snippet view article find links to article

activity, RNA polymerase II-specific Cellular component cytoplasm nucleus autophagosome Biological process apoptotic process regulation of gene expression regulation

Frances Platt (660 words) [view diff] exact match in snippet view article find links to article

Wegiel; W Haung Yu; Ralph A Nixon (1 July 2008). "Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's

PIKFYVE (2,930 words) [view diff] exact match in snippet view article find links to article

phosphorylation myelin assembly receptor-mediated endocytosis regulation of autophagosome assembly phosphatidylinositol phosphate biosynthetic process retrograde

Dromedary (11,228 words) [view diff] exact match in snippet view article find links to article

Intraepithelial Gland in Camel Epididymis with Special Reference to Autophagosome". Microscopy and Microanalysis. 25 (4): 1052–1060. Bibcode:2019MiMic

PINK1 (2,677 words) [view diff] exact match in snippet view article find links to article

complex assembly cellular response to hypoxia negative regulation of autophagosome assembly positive regulation of protein kinase B signaling positive

Adolfo García-Sastre (1,979 words) [view diff] exact match in snippet view article find links to article

A.; Münz, C. (2009). "Matrix Protein 2 of Influenza a Virus Blocks Autophagosome Fusion with Lysosomes". Cell Host & Microbe. 6 (4): 367–380. doi:10

MTOR (12,710 words) [view diff] exact match in snippet view article find links to article

Polson HE, et al. (July 2014). "WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1". Molecular

JUNQ and IPOD (2,453 words) [view diff] exact match in snippet view article find links to article

structure organized by concerted functions of APG genes is essential for autophagosome formation". The EMBO Journal. 20 (21): 5971–81. doi:10.1093/emboj/20

Seipin (2,022 words) [view diff] exact match in snippet view article find links to article

autophagy, and substantially altering the sub-cellular distribution of the autophagosome marker GFP-LC3, which leads to a number of large vacuoles appearing

BNIP3 (2,672 words) [view diff] exact match in snippet view article find links to article

LC3-interacting region (LIR) motif on BNIP3 and facilitates the formation of an autophagosome. Interestingly, when disrupting BNIP3 and LC3 interaction, researchers

EVI5L (1,684 words) [view diff] exact match in snippet view article find links to article

this, the paralogs of the gene are associated with starvation-induced autophagosome formation and trafficking and translocation of GLUT4-containing vesicles

IRGs (2,823 words) [view diff] exact match in snippet view article find links to article

mammalian tissues. Cytoplasmic proteins and organelles are engulfed by autophagosomes which convert LC3-I to LC3-II. The presence of LC3-II serves as a marker

Metal–organic framework (21,288 words) [view diff] exact match in snippet view article find links to article

autophagy flux in HeLa cells treated with 3-MA@ZIF-8 NPs show that the autophagosome formation is significantly blocked, which reveals that the pH-sensitive