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searching for LRRK2 16 found (38 total)

alternate case: lRRK2

Valina L. Dawson (3,370 words) [view diff] exact match in snippet view article find links to article

LRRK2 increase its kinase activity and that inhibition of LRRK2 kinase activity is protective in models of Parkinson’s disease. The increase in LRRK2
Ted M. Dawson (2,719 words) [view diff] exact match in snippet view article find links to article
that inhibiting LRRK2 kinase activity is protective. In collaborative studies, they identified Rab35 as the key Rab linked to LRRK2 neurotoxicity. Their
Vernalis Research (1,094 words) [view diff] exact match in snippet view article find links to article
Chen IJ, et al. (November 2017). "Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase
Sonia Gandhi (scientist) (815 words) [view diff] exact match in snippet view article
Bonifati, Vincenzo; Quinn, Niall P; Lynch, John (2005-01-29). "A common LRRK2 mutation in idiopathic Parkinson's disease". The Lancet. 365 (9457): 415–416
Diapocynin (157 words) [view diff] exact match in snippet view article find links to article
early Parkinson's disease symptoms in the leucine-rich repeat kinase 2 (LRRK2 R1441G) transgenic mouse". Neuroscience Letters. 549: 57–62. doi:10.1016/j
LRRK1 (572 words) [view diff] exact match in snippet view article find links to article
PMID 17353931. Greggio E, Lewis PA, van der Brug MP, et al. (2007). "Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent
Signum Biosciences (831 words) [view diff] exact match in snippet view article find links to article
Jean-Marc; Baekelandt, Veerle (November 7, 2014). "Phosphatases of α-Synuclein, LRRK2, and Tau: Important Players in the Phosphorylation-Dependent Pathology of
CKMT1A (941 words) [view diff] exact match in snippet view article find links to article
Yue Z, Xu Z (October 2011). "Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture
Sharon Tooze (614 words) [view diff] exact match in snippet view article find links to article
independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition". Bioscience Reports. 38 (2): BSR20171669. doi:10.1042/BSR20171669
PAK6 (1,636 words) [view diff] exact match in snippet view article find links to article
junctional protein IQGAP1, E3 ligase Mdm2, and leucine-rich repeat kinase 2 (LRRK2). PAK6 has been shown to interact with Androgen receptor. GRCh38: Ensembl
FAM71E1 (1,222 words) [view diff] exact match in snippet view article find links to article
Pluripotent Stem Cell Lines from Parkinson's Disease Patients Carrying SNCA, LRRK2, PARK2, and GBA Mutations". PLOS ONE. 11 (5): e0154890. Bibcode:2016PLoSO
Edna Schechtman (1,657 words) [view diff] exact match in snippet view article find links to article
I., Gershoni-Baruch, R., Djaldetti, R., ... & Inzelberg, L. (2012). The LRRK2 G2019S mutation is associated with Parkinson disease and concomitant non-skin
Chaperone-mediated autophagy (3,116 words) [view diff] exact match in snippet view article find links to article
Consiglio, A; Raya, A; Sulzer, D; Cuervo, AM (April 2013). "Interplay of LRRK2 with chaperone-mediated autophagy". Nature Neuroscience. 16 (4): 394–406
ISS National Lab (3,335 words) [view diff] exact match in snippet view article find links to article
researchers are growing protein crystals of the Parkinson's disease protein LRRK2. When grown in labs on Earth, the protein's crystals are small and have
C17orf53 (1,389 words) [view diff] exact match in snippet view article find links to article
proteins bearing a leucine-rich nuclear export signal (NES) and of RNAs LRRK2 Leucine-rich repeat serine/threonine-protein kinase 2 association 0.35 Anti
Epigenetics of neurodegenerative diseases (9,792 words) [view diff] exact match in snippet view article find links to article
the alpha-synuclein gene, SNCA, as well as PARK2, PINK1, UCHL1, DJ1, and LRRK2 genes, and fibrillar accumulation of Lewy bodies from misfolded alpha-synuclein