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searching for pINK1 17 found (42 total)

alternate case: PINK1

MUL1 (1,339 words) [view diff] exact match in snippet view article find links to article

allows it to indirectly regulate the PINK1/parkin pathway. Thus, this protein can rescue the phenotypes of PINK1 or parkin knockout mice display, which
Sonia Gandhi (scientist) (865 words) [view diff] exact match in snippet view article
Parkinson's disease Mechanism of Oxidative Stress in Neurodegeneration PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced
Rhomboid protease (4,629 words) [view diff] case mismatch in snippet view article find links to article
"The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking". Journal of Neurochemistry. 117 (5): 856–67. doi:10
Richard Youle (614 words) [view diff] exact match in snippet view article find links to article
division and fusion, in healthy cells. In 2010, he and colleagues found that PINK1 and Parkin, which are mutated in Parkinson's disease, are part of a control
HSH2D (929 words) [view diff] exact match in snippet view article find links to article
as tyrosine kinase non-receptor 2 (TRK2), PTEN-induced putative kinase (PINK1), and Interleukin 2 (IL2). A summary of these proteins is shown below with
Joanne Lemieux (702 words) [view diff] exact match in snippet view article find links to article
Disease Mutations on Mitochondrial Localization and Secondary Structure of PINK1". Biophysical Journal. 110 (3): 230a. Bibcode:2016BpJ...110..230I. doi:10
Lytico-bodig disease (2,174 words) [view diff] exact match in snippet view article find links to article
genes for neurodegeneration. This includes parkinsonism-dementia due to PINK1 homozygous mutations, a DCTN1 mutation that may be causal for Perry syndrome
RNF144A (911 words) [view diff] exact match in snippet view article find links to article
PMC 4645615. PMID 26216882. Pickrell AM, Youle RJ (January 2015). "The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease". Neuron. 85
S-Nitrosylation (2,239 words) [view diff] exact match in snippet view article find links to article
(June 2021). "Neurodegeneration: Impact of S-nitrosylated Parkin, DJ-1 and PINK1 on the pathogenesis of Parkinson's disease". Archives of Biochemistry and
Parkinson's disease (18,337 words) [view diff] exact match in snippet view article find links to article
include SNCA, LRRK2, and VPS35 for autosomal dominant inheritance, and PRKN, PINK1, and DJ1 for autosomal recessive inheritance. Additionally, mutations in
Ted M. Dawson (2,746 words) [view diff] exact match in snippet view article find links to article
doi:10.1172/JCI85456. PMC 4966315. PMID 27348587. Lee, Y.; et al. (2017). "PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal
Mucin-1 (1,787 words) [view diff] case mismatch in snippet view article find links to article
"The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization". Cell Death & Disease. 13
Benedikt Kessler (2,167 words) [view diff] exact match in snippet view article find links to article
Rusilowicz-Jones, Emma (7 July 2020). "USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation". Life Sci Alliance
Seamus Martin (biochemist) (1,192 words) [view diff] exact match in snippet view article
Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy. Molecular Cell 55:451-66. Henry CM and Martin SJ (2017)
Atg8ylation (1,693 words) [view diff] exact match in snippet view article find links to article
for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation". The Journal of Cell Biology. 215 (6):
Patrick Purdon (2,354 words) [view diff] exact match in snippet view article find links to article
Wim (May 29, 2018). Youle, Richard J (ed.). "Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila". eLife. 7: e35878. doi:10
Epigenetics of neurodegenerative diseases (13,392 words) [view diff] exact match in snippet view article find links to article
include mutations to the alpha-synuclein gene, SNCA, as well as PARK2, PINK1, UCHL1, DJ1, and LRRK2 genes, and fibrillar accumulation of Lewy bodies