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searching for leptin 194 found (564 total)

alternate case: Leptin

Pancreatic polypeptide receptor 1 (1,020 words) [view diff] exact match in snippet view article find links to article

Role of Leptin Hormone, Neuropeptide Y, Ghrelin and Leptin/Ghrelin ratio in Obesogenesis: Leptin Hormone, Neuropeptide Y, Ghrelin and Leptin/Ghrelin ratio"

Maria Leptin (1,953 words) [view diff] exact match in snippet view article find links to article

Maria Leptin (born 1954) is a German developmental biologist and immunologist, and the current president of the European Research Council. She was the

LSL (gene) (370 words) [view diff] exact match in snippet view article

Leptin, serum levels of, also known as LSL, is a human gene. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library

SNX4 (568 words) [view diff] exact match in snippet view article find links to article

intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth

European Molecular Biology Organization (756 words) [view diff] exact match in snippet view article find links to article

Directors Raymond Appleyard, John Tooze, Frank Gannon, Hermann Bujard and Maria Leptin. In 2011, EMBO established a Policy Programme which interacts with policymakers

BBS4 (775 words) [view diff] exact match in snippet view article find links to article

polymerization negative regulation of appetite by leptin-mediated signaling pathway response to stimulus leptin-mediated signaling pathway dendrite development

MKKS (811 words) [view diff] exact match in snippet view article find links to article

by leptin-mediated signaling pathway response to stimulus negative regulation of blood pressure convergent extension involved in gastrulation leptin-mediated

BBS2 (687 words) [view diff] exact match in snippet view article find links to article

motility negative regulation of appetite by leptin-mediated signaling pathway response to stimulus leptin-mediated signaling pathway negative regulation

Janus kinase 1 (2,423 words) [view diff] exact match in snippet view article find links to article

neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R). It is also important for transducing a signal by type I (IFN-α/β) and

List of fellows of the Royal Society elected in 2022 (162 words) [view diff] exact match in snippet view article find links to article

Canfield Titia de Lange George Gao Michael Grätzel Hiroshi Hamada [ja] Maria Leptin Carlos Nobre Peter Scholze Howard Stone "Outstanding scientists elected

STAT3 (3,340 words) [view diff] exact match in snippet view article find links to article

PMID 10490649. Sanchez-Margalet V, Martin-Romero C (July 2001). "Human leptin signaling in human peripheral blood mononuclear cells: activation of the

Type I cytokine receptor (514 words) [view diff] exact match in snippet view article find links to article

receptor Thrombopoietin receptor Growth hormone receptor Prolactin receptor Leptin receptor Oncostatin M receptor Leukemia inhibitory factor receptor Lichtman

Black Iberian pig (667 words) [view diff] exact match in snippet view article find links to article

intake and propensity to obesity, compatible with high values of serum leptin. The Iberian pig can be either red or dark in colour, if black ranging from

Chief cell (964 words) [view diff] exact match in snippet view article find links to article

evidence that the gastric chief cell secretes leptin in response to the presence of food in the stomach. Leptin has been found in the pepsinogen granules

Michael Warren Schwartz (696 words) [view diff] exact match in snippet view article find links to article

receptors in leptin effects. Nature. 390:349, 1997. Schwartz MW, Seeley RJ, Weigle DS, Woods SC, Campfield LA, Burn P, Baskin DG. Leptin increases proopimelanocortin

Ventromedial nucleus of the hypothalamus (1,818 words) [view diff] exact match in snippet view article find links to article

a VMH lesion cannot respond. A lesion to the VMH makes rats overproduce leptin, which they cannot respond to causing them to over eat, leading to obesity

Caniformia (1,976 words) [view diff] exact match in snippet view article find links to article

Nikolas (ed.). "Phocid seal leptin: Tertiary structure and hydrophobic receptor binding site preservation during distinct leptin gene evolution". PLOS ONE

Anterior pituitary (2,584 words) [view diff] exact match in snippet view article find links to article

(2007) Leptin and the regulation of the hypothalamic-pituitary-adrenal axis. Int Rev Cytol. 263: 63-102. Sone, M. and Osamura, R.Y. (2001) Leptin and the

Plateau pika (1,321 words) [view diff] exact match in snippet view article find links to article

metabolic rate and non- shivering thermogenesis along with the production of leptin which is a thermogenesis regulatory hormone. Unlike hibernating mammals

Stephen O'Rahilly (1,623 words) [view diff] exact match in snippet view article find links to article

A.; O'Rahilly, S. (1999). "Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency". New England Journal of Medicine. 341 (12):

Astrocyte (9,353 words) [view diff] exact match in snippet view article find links to article

hypothalamus that are responsive to a hormone called leptin that is produced by fat cells. Leptin-sensitive neurons regulate appetite and body weight.

Adipose tissue macrophages (2,339 words) [view diff] exact match in snippet view article find links to article

adipose tissue ranges from 10% in lean mice and humans up to 50% in obese leptin deficient mice, and up to 40% in obese humans. ATMs comprise nearly 50%

Suppressor of cytokine signalling (396 words) [view diff] exact match in snippet view article find links to article

diabetes, as it has been found that SOCS3 plays an important role in proper leptin signaling. Babon, Jeffrey; Nicola, Nicos A (August 2012). "The biology and

Nutrient sensing (1,489 words) [view diff] exact match in snippet view article find links to article

function of nutrient sensing, whereas other receptors (e.g. insulin receptors, leptin receptors) are extensively multifunctional and perform many functions besides

Satiety (421 words) [view diff] exact match in snippet view article find links to article

Sudar-Milovanovic E, Soskic S, Essack M, Arya S, Stewart AJ, et al. (2021). "Leptin and Obesity: Role and Clinical Implication". Frontiers in Endocrinology

Sean J. Morrison (2,332 words) [view diff] exact match in snippet view article find links to article

cells and Leptin Receptor+ perivascular stromal cells are the major sources of factors required for HSC maintenance in the bone marrow. The Leptin Receptor+

Detlef Müller (mathematician) (477 words) [view diff] exact match in snippet view article

in R n {\displaystyle \mathbb {R} ^{n}} ) under the supervision of Horst Leptin (1927–2017). Müller habilitated in 1984 in Kiel. He spent the academic year

Spinal trigeminal nucleus (295 words) [view diff] exact match in snippet view article find links to article

Moar KM, Findlay PA, Hoggard N, Adam CL (September 1998). "Association of leptin receptor (OB-Rb), NPY and GLP-1 gene expression in the ovine and murine

Persimmon vinegar (285 words) [view diff] exact match in snippet view article find links to article

2017. Vairappan, Balasubramaniyan (2015). "15. Cholesterol Regulation by Leptin in Alcoholic Liver Disease". In Patel, Vinood (ed.). Molecular Aspects of

EMBO Membership (394 words) [view diff] exact match in snippet view article find links to article

Molecular Biology Organization. Archived from the original on 2016-04-18. Leptin, Maria (2010). "Spreading the Spirit of EMBO". Science. 327 (5962): 126

SIGLEC5 (733 words) [view diff] exact match in snippet view article find links to article

Brinkman-Van der Linden EC, Altmann SW, et al. (1999). "OB-BP1/Siglec-6. A leptin- and sialic acid-binding protein of the immunoglobulin superfamily". J.

Catheter (3,048 words) [view diff] exact match in snippet view article find links to article

hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice" [Molecular Metabolism 13 (2018)

Rexford S. Ahima (903 words) [view diff] exact match in snippet view article find links to article

JS Flier, Role of leptin in the neuroendocrine response to fasting, in Nature. Vol. 382, nº 6588; 250–252. 2000 with JS Flier, Leptin, in Annual Review

Gonadotropic cell (336 words) [view diff] exact match in snippet view article find links to article

Scherer PE, Lowell BB, Brüning JC, Elmquist JK (2010). "Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis

ACAT1 (2,322 words) [view diff] exact match in snippet view article find links to article

activity is enhanced ACAT1's expression is promoted transcriptionally by leptin, angiotensin II, and insulin in human monocytes/macrophages. Insulin-mediated

Bioenergetics (3,517 words) [view diff] exact match in snippet view article find links to article

mediators that carry information about energy balance, including glucose, leptin, and ghrelin. ... Accordingly, orexin plays a role in the regulation of

European Research Council (2,371 words) [view diff] exact match in snippet view article find links to article

president of the European Research Council. 30 June 2021, Professor Maria Leptin was named president of the ERC from 1 October 2021. The ERC Scientific Council

Kent Holtorf (1,813 words) [view diff] exact match in snippet view article find links to article

lose weight as leptin resistance, undiagnosed hypothyroidism, environmental toxins, hypometabolism and dysfunctional weight set-point. Leptin resistance is

Michael Cowley (1,375 words) [view diff] exact match in snippet view article find links to article

Brain Inflammation in Leptin Resistance 2010 NHMRC Equipment grant 2010-2012 aHeart Research Foundation Project Grant: Does Leptin Cause Hypertension? 2010-2013

Natalie Strynadka (657 words) [view diff] exact match in snippet view article find links to article

G. V.; Tu, Y; Birnbaum, M. J.; Lopaschuk, G. D.; Moran, T. H. (2007). "Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake". Proceedings

ENPP3 (737 words) [view diff] exact match in snippet view article find links to article

Elbatarny HS, Maurice DH (October 2005). "Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing

Sirtuin 1 (3,126 words) [view diff] exact match in snippet view article find links to article

negative regulation of helicase activity cholesterol homeostasis response to leptin cellular response to hypoxia triglyceride mobilization negative regulation

Abdominal obesity (8,558 words) [view diff] exact match in snippet view article find links to article

presence of cortisol, a hormone that leads to more belly fat deposits and leptin resistance. Self-motivation by understanding the risks associated with abdominal

AMP-activated protein kinase (7,149 words) [view diff] exact match in snippet view article find links to article

are other mechanisms by which AMPK is inhibited or activated by insulin, leptin, and diacylglycerol by inducing various other phosphorylations. AMPK may

Tribble (1,012 words) [view diff] exact match in snippet view article find links to article

238–250. doi:10.1016/j.cellsig.2006.06.010. PMID 16963228. Seher, T. C.; Leptin, M. (2000-06-01). "Tribbles, a cell-cycle brake that coordinates proliferation

Eric R. Braverman (896 words) [view diff] exact match in snippet view article find links to article

in patients: the utility of body mass index (BMI), percent body fat, and leptin". PLOS ONE. 7 (4): e33308. Bibcode:2012PLoSO...733308S. doi:10.1371/journal

Intrauterine growth restriction (4,410 words) [view diff] exact match in snippet view article find links to article

abnormalities Placental genes Maternal genes: Endothelin-1 over-expression, Leptin under-expression Fetal genes If the cause of IUGR is extrinsic to the fetus

Amenable group (3,223 words) [view diff] exact match in snippet view article find links to article

Haar measure such that m(U Δ gU)/m(U) is arbitrarily small for g in F. Leptin's condition. For every finite (or compact) subset F of G there is a measurable

SOCS7 (642 words) [view diff] exact match in snippet view article find links to article

"Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear

Eleftheria Maratos-Flier (1,275 words) [view diff] exact match in snippet view article find links to article

Bradford; Maratos-Flier, Eleftheria; Flier, Jeffrey S. (1996-07-01). "Role of leptin in the neuroendocrine response to fasting". Nature. 382 (6588): 250–252

Ganglioside (1,307 words) [view diff] exact match in snippet view article find links to article

ganglioside expression in mediobasal hypothalamic neurons deregulates neuronal leptin and insulin signaling. "Gangliosides, structure, occurrence, biology and

APOM (1,076 words) [view diff] exact match in snippet view article find links to article

Nilsson-Ehle P, Ahrén B (October 2004). "Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects". The Journal of Nutritional

Stephen R. Bloom (614 words) [view diff] exact match in snippet view article find links to article

G. M.; Matarese, G.; Howard, J. K.; Baker, R. J.; Bloom, S. R. (1998). "Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression"

Wolf Prize in Medicine (220 words) [view diff] exact match in snippet view article find links to article

2018 No award 2019 Jeffrey M. Friedman United States for the discovery of Leptin and the entirely new endocrine system controlling body weight (and many

Endothelin 1 (341 words) [view diff] exact match in snippet view article find links to article

chemokine-mediated signaling pathway phosphatidylinositol 3-kinase signaling response to leptin positive regulation of mitotic nuclear division cellular response to hypoxia

CEBP (50 words) [view diff] exact match in snippet view article find links to article

CEBP may refer to: CEBPA, a human gene that modulates leptin expression CCAAT-enhancer-binding proteins or C/EBPs This disambiguation page lists articles

Pennington Biomedical Research Center (784 words) [view diff] exact match in snippet view article find links to article

Genomics, Regulation of Gene Expression Neurobiology: Autonomic Neuroscience, Leptin Signaling in the Brain, Neurobiology & Nutrition, Neurobiology of Metabolic

Thrifty gene hypothesis (3,535 words) [view diff] exact match in snippet view article find links to article

PMID 21198561. Farooqi; et al. (1999). "Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency". N Engl J Med. 341 (12): 879–884. doi:10

PRKAA2 (969 words) [view diff] exact match in snippet view article find links to article

Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, Kahn BB (2002). "Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase"

Bone marrow adipose tissue (5,156 words) [view diff] exact match in snippet view article find links to article

hypertensive heart failure; in response to hormones such as oestrogen, leptin, and growth hormone; with exercise-induced weight loss or bariatric surgery;

Metamorphosis (2,677 words) [view diff] exact match in snippet view article find links to article

or not to eat: ontogeny of hypothalamic feeding controls and a role for leptin in modulating life-history transition in amphibian tadpoles". The Royal

3-Aminoisobutyric acid (361 words) [view diff] exact match in snippet view article find links to article

Massart J, Fromenty B (June 2010). "Effects of β-aminoisobutyric acid on leptin production and lipid homeostasis: mechanisms and possible relevance for

ZBTB17 (1,218 words) [view diff] exact match in snippet view article find links to article

2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the

Food craving (3,275 words) [view diff] exact match in snippet view article find links to article

very active, increasing the levels of pleasure. Hormones like dopamine, leptin, ghrelin, and cortisol are released, as well as insulin due to this stimulation

Jessie Stevenson Kovalenko Medal (87 words) [view diff] exact match in snippet view article find links to article

treatment for two leukemias. Jeffrey M. Friedman 2007 For the discovery of leptin and its role in the regulation of appetite, energy expenditure, and the

Interleukin-1 family (6,005 words) [view diff] exact match in snippet view article find links to article

metabolism. For instance, Rothwell and coworkers reported evidence that Leptin actions on food intake and body temperature are mediated by IL-1 at the

Takifugu rubripes (747 words) [view diff] exact match in snippet view article find links to article

(meaning "22nd-century fugu"), has been genetically modified by removing four leptin receptor genes that control appetite. The result has increased appetite

UCP3 (1,932 words) [view diff] exact match in snippet view article find links to article

thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin". The Journal of Biological Chemistry. 272 (39): 24129–32. doi:10.1074/jbc

Obesogen (6,293 words) [view diff] exact match in snippet view article find links to article

though born with a lower birth weight, almost always developed obesity, high leptin levels, and altered glucose response pathways. Both phytoestrogen and DES

PER2 (1,760 words) [view diff] exact match in snippet view article find links to article

vivo. Mice with a genomic deletion spanning this GRE expressed elevated leptin levels and were protected from glucose intolerance and insulin resistance

UGCG (876 words) [view diff] exact match in snippet view article find links to article

lipidation regulation of signal transduction keratinocyte differentiation leptin-mediated signaling pathway cornified envelope assembly Sources:Amigo / QuickGO

11β-Hydroxysteroid dehydrogenase (1,900 words) [view diff] exact match in snippet view article find links to article

hyperlipidemia on 11β-hydroxysteroid-dehydrogenase, glucocorticoid receptor, and leptin expression in insulin-sensitive tissues of cats" (PDF). Domestic Animal

Growth hormone secretagogue receptor (1,608 words) [view diff] exact match in snippet view article find links to article

Elmquist J (August 2009). "Depression and metabolism: linking changes in leptin and ghrelin to mood". F1000 Biology Reports. 1 (63): 63. doi:10.3410/b1-63

Zeranol (457 words) [view diff] exact match in snippet view article find links to article

"Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol". Anticancer Research. 29 (11): 4621–4628. PMID 20032412

Hypocretin (orexin) receptor 2 (1,672 words) [view diff] exact match in snippet view article

orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity". Cell Metabolism. 9 (1): 64–76. doi:10.1016/j.cmet.2008.10

Vagus nerve (3,160 words) [view diff] exact match in snippet view article find links to article

de Lartigue G, Ronveaux CC, Raybould HE (September 2014). "Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity"

Nuclear receptor 4A3 (1,326 words) [view diff] exact match in snippet view article find links to article

II regulation of smooth muscle cell proliferation cellular response to leptin stimulus transcription, DNA-templated positive regulation of cardiac muscle

Development of the human body (2,850 words) [view diff] exact match in snippet view article find links to article

axis, androgens, estrogens, vitamin D, glucocorticoids and possibly leptin. GH is secreted by the anterior pituitary gland in response to hypothalamic

Collagen, type VI, alpha 3 (1,608 words) [view diff] exact match in snippet view article find links to article

Mellgren G, Nystrom F, Carlsson LM, Kos K (Jan 2015). "COL6A3 is regulated by leptin in human adipose tissue and reduced in obesity". Endocrinology. 156 (1):

Liver X receptor alpha (1,641 words) [view diff] exact match in snippet view article find links to article

Wang MY, Chen L, Clark GO, Lee Y, Stevens RD, Ilkayeva OR, et al. (2010). "Leptin therapy in insulin-deficient type I diabetes". Proceedings of the National

Cannabinoid (7,814 words) [view diff] exact match in snippet view article find links to article

expression and suppressing the activity of leptin, the Tlc1 antagonist. It is proposed that the competition of leptin and cannabinoids for Tlc1 is implicated

Chromosome 2 (2,534 words) [view diff] exact match in snippet view article find links to article

head) LCLAT1: encoding protein Lysocardiolipin acyltransferase 1 LEPQTL1: Leptin, serum levels of MBOAT2: encoding protein Membrane bound o-acyltransferase

NWD1 (314 words) [view diff] exact match in snippet view article find links to article

signaling during prostate cancer progression. Stein C, Caccamo M, Laird G, Leptin M (2007). "Conservation and divergence of gene families encoding components

Ontogeny (3,246 words) [view diff] exact match in snippet view article find links to article

and Evolution of Animal Life". biocyclopedia.com. Retrieved 8 April 2022. Leptin, Maria (1 March 2005). "Gastrulation Movements: the Logic and the Nuts and

Sympathetic nervous system (3,742 words) [view diff] exact match in snippet view article find links to article

An example of this includes the retraction of sympathetic neurons due to leptin resistance, which is linked to obesity. Another example, although more research

Fibroblast growth factor 23 (1,840 words) [view diff] exact match in snippet view article find links to article

negative regulation of osteoblast differentiation cellular response to leptin stimulus positive regulation of transcription, DNA-templated fibroblast

Sympathetic nervous system (3,742 words) [view diff] exact match in snippet view article find links to article

An example of this includes the retraction of sympathetic neurons due to leptin resistance, which is linked to obesity. Another example, although more research

HK3 (1,868 words) [view diff] exact match in snippet view article find links to article

2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the

Nestin (protein) (1,923 words) [view diff] exact match in snippet view article

exclusive expression in intramesenchymal skin compartments and regulation by leptin". Journal of Investigative Dermatology. 129 (11): 2711–20. doi:10.1038/jid

Calciphylaxis (2,877 words) [view diff] exact match in snippet view article find links to article

in vitro, mediated by vascular endothelial growth factor A (VEGF-A) and leptin released by adipocytes. Given that calciphylaxis tends to affect adipose

SNX2 (1,067 words) [view diff] exact match in snippet view article find links to article

Molecular function protein homodimerization activity insulin receptor binding leptin receptor binding epidermal growth factor receptor binding protein binding

C1QTNF3 (582 words) [view diff] exact match in snippet view article find links to article

Neumeier M, Weigert J, Schäffler A, Buechler C (2007). "Plasma levels of leptin, omentin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26)

S. Ganesh (1,244 words) [view diff] exact match in snippet view article find links to article

Mishra, Rohit; Ganesh, Subramaniam (15 December 2017). "Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in

INHBB (1,551 words) [view diff] exact match in snippet view article find links to article

regulation of follicle-stimulating hormone secretion cellular response to leptin stimulus oocyte development positive regulation of ovulation cellular response

Glucomannan (2,329 words) [view diff] exact match in snippet view article find links to article

2009). "Immediate and long-term effects of glucomannan on total ghrelin and leptin in type 2 diabetes mellitus". Diabetes Research and Clinical Practice. 83

Initiative for Science in Europe (290 words) [view diff] exact match in snippet view article find links to article

Celis, Federico Mayor Zaragoza former Director General of UNESCO, and Maria Leptin (former director of EMBO and President of the European Research Council)

List of human clusters of differentiation (492 words) [view diff] exact match in snippet view article find links to article

treatment. CD295 Leptin receptor (LEPR or OBR); LEPR functions as a receptor for the fat cell-specific hormone leptin. Variations in the leptin receptor have

PTEN (gene) (3,405 words) [view diff] exact match in snippet view article

to activity cellular response to insulin stimulus cellular response to leptin stimulus positive regulation of neuron differentiation cellular response

Karen Teff (474 words) [view diff] exact match in snippet view article find links to article

Elliot, Sharon (2004). "Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides

Deborah Muoio (572 words) [view diff] exact match in snippet view article find links to article

Frederick T; Tapscott, Edward B; Coleman, Rosalind A (1 August 1997). "Leptin Directly Alters Lipid Partitioning in Skeletal Muscle". Diabetes. 46 (8):

FGF19 (2,570 words) [view diff] exact match in snippet view article find links to article

"Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes". Endocrinology. 145 (6): 2594–603. doi:10.1210/en.2003-1671

Lasker Award (1,590 words) [view diff] exact match in snippet view article find links to article

excellence in biomedical research. 2010 Basic Douglas L. Coleman Discovery of leptin, a hormone that regulates appetite and body weight – a breakthrough that

Breast cancer (15,172 words) [view diff] exact match in snippet view article find links to article

facilitate malignant cell growth. In breast adipose tissue, overexpression of leptin leads to increased cell proliferation and cancer. Some mutations associated

Salidroside (621 words) [view diff] exact match in snippet view article find links to article

mice by repressing inflammation in white adipose tissues and improving leptin sensitivity in hypothalamus". Scientific Reports. 6 (1): 25399. Bibcode:2016NatSR

Thrifty phenotype (1,875 words) [view diff] exact match in snippet view article find links to article

changes are also believed to possibly be inherited across generations. Leptin has been identified as a possible gene for the acquisition of these thrifty

Setmelanotide (1,411 words) [view diff] exact match in snippet view article find links to article

deficiency, proprotein subtilisin/kexin type 1 (PCSK1) deficiency, and leptin receptor (LEPR) deficiency confirmed by genetic testing demonstrating variants

DGKZ (929 words) [view diff] exact match in snippet view article find links to article

(2001). "Diacylglycerol kinase zeta in hypothalamus interacts with long form leptin receptor. Relation to dietary fat and body weight regulation". J. Biol.

Pinniped (12,603 words) [view diff] exact match in snippet view article find links to article

Nikolaidis N (ed.). "Phocid seal leptin: Tertiary structure and hydrophobic receptor binding site preservation during distinct leptin gene evolution". PLOS ONE

Octreotide (2,731 words) [view diff] exact match in snippet view article find links to article

"There were no statistically significant changes in QoL scores, body fat, leptin concentration, Beck Depression Inventory, or macronutrient intake", although

Mirela Delibegovic (1,331 words) [view diff] exact match in snippet view article find links to article

Barbara B. (2006). "Neuronal PTP1B regulates body weight, adiposity and leptin action". Nature Medicine. 12 (8): 917–924. doi:10.1038/nm1435. ISSN 1546-170X

Microdialysis (3,787 words) [view diff] exact match in snippet view article find links to article

hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice" [Molecular Metabolism 13 (2018)

Adrenalectomy (1,661 words) [view diff] exact match in snippet view article find links to article

Gemmill ME, Eskay RL, Hall NL, Douglass LW, Castonguay TW (February 2003). "Leptin suppresses food intake and body weight in corticosterone-replaced adrenalectomized

Peter Tishler (954 words) [view diff] exact match in snippet view article find links to article

Palmer, L. J.; Jenny, N. S.; Redline, S. (Mar 2005). "Linkage of serum leptin levels in families with sleep apnea". Int J Obes (Lond). 29 (3): 260–7.

MRC Laboratory of Molecular Biology (3,821 words) [view diff] exact match in snippet view article find links to article

Ingham Robert Insall David Ish-Horowicz Cynthia Kenyon Judith Kimble Maria Leptin Arthur M. Lesk Harvey Lodish Philippa Marrack Laura Machesky Yanlan Mao

Thierry Bogaert (313 words) [view diff] exact match in snippet view article find links to article

becomes localized to muscle attachments, Cell. 1987 Dec 24;51(6):929–40 Leptin M, Bogaert T, Lehmann R, Wilcox M, The function of PS integrins during Drosophila

SNX1 (1,095 words) [view diff] exact match in snippet view article find links to article

Molecular function protein homodimerization activity insulin receptor binding leptin receptor binding epidermal growth factor receptor binding protein binding

GNRH2 (856 words) [view diff] exact match in snippet view article find links to article

Islami D, Bischof P, Chardonnens D (2004). "Possible interactions between leptin, gonadotrophin-releasing hormone (GnRH-I and II) and human chorionic gonadotrophin

Mir-498 microRNA precursor family (376 words) [view diff] exact match in snippet view article find links to article

2012). "Low amino acids affect expression of 11β-HSD2 in BeWo cells through leptin-activated JAK-STAT and MAPK pathways". Amino Acids. 42 (5): 1879–87. doi:10

Citalopram (4,603 words) [view diff] exact match in snippet view article find links to article

selective serotonin reuptake inhibitor citalopram on insulin sensitivity, leptin and basal cortisol secretion in depressed and non-depressed euglycemic women

Intelectin-1 (822 words) [view diff] exact match in snippet view article find links to article

Weigert J, Schäffler A, Buechler C (February 2007). "Plasma levels of leptin, omentin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26)

Fructolysis (1,949 words) [view diff] exact match in snippet view article find links to article

Sharon S. (2004-06-01). "Dietary Fructose Reduces Circulating Insulin and Leptin, Attenuates Postprandial Suppression of Ghrelin, and Increases Triglycerides

Masashi Yanagisawa (2,678 words) [view diff] exact match in snippet view article find links to article

Rafal M.; Yanagisawa, Masashi (2004). "Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41".

Stearoyl-CoA 9-desaturase (3,137 words) [view diff] exact match in snippet view article find links to article

SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors". The Journal of Biological Chemistry. 278 (36): 33904–33911

List of female fellows of the Royal Society (6,775 words) [view diff] exact match in snippet view article find links to article

2021. "Titia de Lange". The Royal Society. Retrieved 11 May 2022. "Maria Leptin". The Royal Society. Retrieved 11 May 2022. "Academician Eva-Mari Aro ForMemRS"

Lafora disease (2,694 words) [view diff] exact match in snippet view article find links to article

Anupama; Mishra, Rohit; Ganesh, Subramaniam (2017-12-15). "Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in

Adiponectin receptor 1 (1,252 words) [view diff] exact match in snippet view article find links to article

plasma membrane Biological process glucose homeostasis lipid metabolism leptin-mediated signaling pathway adiponectin-activated signaling pathway fatty

GPLD1 (984 words) [view diff] exact match in snippet view article find links to article

"Sensory nerves in central and peripheral control of pancreatic integrity by leptin and melatonin". Journal of Physiology and Pharmacology. 53 (1): 51–74. PMID 11939719

Plains spadefoot toad (1,779 words) [view diff] exact match in snippet view article find links to article

1098/rstb.2016.0066. PMC 5312016. PMID 28193811. Garcia, N (April 2015). "Leptin Manipulation Reduces Appetite and Causes a Switch in Mating Preference in

Rev-ErbA alpha (4,270 words) [view diff] exact match in snippet view article find links to article

process transcription initiation from RNA polymerase II promoter response to leptin negative regulation of transcription, DNA-templated cellular response to

Obesity and cancer (2,449 words) [view diff] exact match in snippet view article find links to article

of proinflammatory cytokines, endocrine hormones, adipokines including leptin and adiponectin, insulin, growth factors, estrogen, progesterone and cell

Apsines (sophist) (183 words) [view diff] exact match in snippet view article

required the presence of a Roman proconsul to suppress. Ulpian, ad Demosth. Leptin. p. 11; comp. Schol. ad Hermog. p. 402 Eunapius, Lives of the Sophists p

Altered state of consciousness (6,099 words) [view diff] exact match in snippet view article find links to article

Young T, Mignot E (2004). "Short Sleep Duration Is Associated with Reduced Leptin, Elevated Ghrelin, and Increased Body Mass Index". PLOS Med. 1 (3): e62

Mayumi Kimura (198 words) [view diff] exact match in snippet view article find links to article

Planck Institute of Psychiatry from 2003 to 2018. Yu, W. H., et al. "Role of leptin in hypothalamic–pituitary function." Proceedings of the National Academy

Donkey milk (3,651 words) [view diff] exact match in snippet view article find links to article

have also been determined. Donkey mammary secretions contain human-like leptin at levels close to human milk (3.35 e 5.32 ng/mL milk). The bioactive peptides

Cyclin A2 (2,580 words) [view diff] exact match in snippet view article find links to article

response to platelet-derived growth factor stimulus cellular response to leptin stimulus cell division positive regulation of transcription, DNA-templated

Fibrinogen beta chain (972 words) [view diff] exact match in snippet view article find links to article

blood coagulation extracellular matrix organization cellular response to leptin stimulus response to calcium ion positive regulation of substrate adhesion-dependent

Tianeptine (6,477 words) [view diff] exact match in snippet view article find links to article

(May 1998). "Hypothalamic CART is a new anorectic peptide regulated by leptin". Nature. 393 (6680): 72–6. Bibcode:1998Natur.393...72K. doi:10.1038/29993

Benjamin G. Neel (845 words) [view diff] exact match in snippet view article find links to article

identified a protein that enables the body to overcome resistance to the hormone leptin. In 2006, he was one of the lead scientists who discovered that mutations

Advanced glycation end-product (3,736 words) [view diff] exact match in snippet view article find links to article

divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling". Laboratory Investigation. 94 (5): 503–516. doi:10.1038/labinvest

Glucokinase (5,655 words) [view diff] exact match in snippet view article find links to article

homeostasis calcium ion import carbohydrate phosphorylation cellular response to leptin stimulus negative regulation of gluconeogenesis cellular response to insulin

ABCA7 (2,880 words) [view diff] exact match in snippet view article find links to article

Alzheimer's Disease Risk Gene ABCA7 Alters White Adipose Tissue Development and Leptin Levels". Journal of Alzheimer's Disease Reports. 1 (1): 237–247. doi:10

Aphepsion (125 words) [view diff] exact match in snippet view article find links to article

orator, spoke for Aphepsion, and Demosthenes for Ctesippus. Argum. ad Dem. Leptin. p. 453 Dem. c. Lept. p. 501 Wolf, Proleg. in Demosth. Lept. p. 48, &c.

Breast milk (8,713 words) [view diff] exact match in snippet view article find links to article

an infant breast milk is associated with lower insulin levels and higher leptin levels compared feeding an infant via powdered-formula. Many of the infection-fighting

Brown bear (14,645 words) [view diff] exact match in snippet view article find links to article

Tuomala-Saramäki, T.; Laine, T. (1998). "Seasonal changes in fatty acids and leptin contents in the plasma of the European brown bear (Ursus arctos arctos)"

Hyperphagia (ecology) (594 words) [view diff] exact match in snippet view article

Tuomala-Saramäki, T.; Laine, T. (1998). "Seasonal changes in fatty acids and leptin contents in the plasma of the European brown bear (Ursus arctos arctos)"

PGDS (821 words) [view diff] exact match in snippet view article find links to article

(2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the

Frog (19,782 words) [view diff] exact match in snippet view article find links to article

or not to eat: Ontogeny of hypothalamic feeding controls and a role for leptin in modulating life-history transition in amphibian tadpoles". Proceedings

Male infertility (7,707 words) [view diff] exact match in snippet view article find links to article

hypogonadotropic hypogonadism. Animal models indicate that obesity causes leptin insensitivity in the hypothalamus, leading to decreased Kiss1 expression

Cocaine (19,615 words) [view diff] exact match in snippet view article find links to article

serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and relationships with cardiorespiratory and subjective responses"

MARCM (1,436 words) [view diff] exact match in snippet view article find links to article

2883–2893. doi:10.1242/dev.024380. PMID 18653555. Baer, MM; Bilstein A; Leptin M. (2007-07-01). "A clonal genetic screen for mutants causing defects in

Phosphotyrosine interaction domain containing 1 (551 words) [view diff] exact match in snippet view article find links to article

regulation of reactive oxygen species metabolic process cellular response to leptin stimulus cellular response to cytokine stimulus positive regulation of ATP

Low-density lipoprotein receptor-related protein 8 (3,439 words) [view diff] exact match in snippet view article find links to article

TM, Strasser V, Nimpf J, Schneider WJ (2003). "A model for modulation of leptin activity by association with clusterin". FASEB J. 17 (11): 1505–7. doi:10

LYN (3,807 words) [view diff] exact match in snippet view article find links to article

Müller G, Koca G, Fürnsinn C, Waldhäusl W, Roden M (Jul 2002). "Short-term leptin-dependent inhibition of hepatic gluconeogenesis is mediated by insulin receptor

Delayed puberty (4,987 words) [view diff] exact match in snippet view article find links to article

17.05044-7. PMID 28745464. Pankov YA (September 2015). "[Kisspeptin and leptin in the regulation of fertility]". Molekuliarnaia Biologiia. 49 (5): 707–15

Twentieth Indian Expedition to Antarctica (1,122 words) [view diff] exact match in snippet view article find links to article

collecting water and plankton samples. Human Biology and Medicine Studies on leptin neuropeptide status in human beings was conducted in three phases viz.,

Education in New York City (5,122 words) [view diff] exact match in snippet view article find links to article

AIDS "cocktail" drug therapy, and identified the weight-regulating hormone leptin. Twenty-three Nobel Prize winners have been associated with the university

Cyclin D1 (5,694 words) [view diff] exact match in snippet view article find links to article

transition of mitotic cell cycle lactation response to ethanol response to leptin negative regulation of epithelial cell differentiation fat cell differentiation

DDX41 (996 words) [view diff] exact match in snippet view article find links to article

Biotechnology Information, U.S. National Library of Medicine. Irion U, Leptin M (December 1999). "Developmental and cell biological functions of the Drosophila

Eating disorders and memory (7,574 words) [view diff] exact match in snippet view article find links to article

Previous studies have identified the effect of the adipocyte hormone leptin, reveal that leptin treatments reverse obesity in knockout mice (ob/ob), and that

STAR (gene) (592 words) [view diff] exact match in snippet view article

synaptic plasticity response to insecticide response to ethanol response to leptin bile acid biosynthetic process cellular response to lipopolysaccharide response

Dromedary (11,382 words) [view diff] exact match in snippet view article find links to article

camel to food and water shortage: new data on adipocyte size and plasma leptin". In Faye, B.; Esenov, P. (eds.). Desertification Combat and Food Safety:

Epigenetics of physical exercise (8,901 words) [view diff] exact match in snippet view article find links to article

suppressor, was found to be upregulated in obesity and was shown to induce leptin and insulin resistance. The paper states "increased SOCS3 expression in

Epigenetics (18,271 words) [view diff] exact match in snippet view article find links to article

programming effects of gestational calorie restriction and their reversibility by leptin supplementation". Scientific Reports. 5 (1): 9088. Bibcode:2015NatSR...5E9088K

Estrogen receptor alpha (6,133 words) [view diff] exact match in snippet view article find links to article

K, Cetin ES, et al. (May 2014). "Genetic variants of estrogen beta and leptin receptors may cause gynecomastia in adolescent". Gene. 541 (2): 101–106

Metallothionein-3 (941 words) [view diff] exact match in snippet view article find links to article

hypoxia zinc ion homeostasis protein kinase B signaling histone modification leptin-mediated signaling pathway removal of superoxide radicals astrocyte development

Breast reduction (6,124 words) [view diff] exact match in snippet view article find links to article

recognized as a major endocrine organ[1], as it produces hormones such as leptin, resistin, and the cytokine TNFα. Moreover, adipose tissue can affect other

Abul Hasan Siddiqi (902 words) [view diff] exact match in snippet view article find links to article

post doctoral studies at Heidelberg University under the guidance of Horst Leptin (1971–72) as a fellow of German Academic Exchange Service.[citation needed]

Endogenous retrovirus (8,298 words) [view diff] exact match in snippet view article find links to article

splice sites either by direct integration into the gene, as with the human leptin hormone receptor, or driven by the expression of an upstream LTR, as with

Institute of Molecular Biotechnology (2,636 words) [view diff] exact match in snippet view article find links to article

Harbor Laboratory), Guido Kroemer (University of Paris Descartes), Maria Leptin (President of the European Research Council ERC and Director of EMBO), Gary

Exercise and androgen levels (2,951 words) [view diff] exact match in snippet view article find links to article

Chavarren J, Dorado C, Calbet JA (2006). "Serum free testosterone, leptin and soluble leptin receptor changes in a 6-week strength-training programme". The

SUCNR1 (8,861 words) [view diff] exact match in snippet view article find links to article

adipocytes controls energy metabolism by modulating circadian clock and leptin expression". Cell Metabolism. 35 (4): 601–619.e10. doi:10.1016/j.cmet.2023

12-Hydroxyheptadecatrienoic acid (3,733 words) [view diff] exact match in snippet view article find links to article

in the db/db mouse model of obesity, diabetes, and dyslipidemia due to leptin receptor deficiency. 12-HHT accumulated in the wounds of the former mouse

Tree swallow (9,181 words) [view diff] exact match in snippet view article find links to article

Energy balance in migratory birds: Insights from mitochondrial genomes and leptin receptor biology (PhD). Cornell University. pp. 91–122. Whittingham, Linda

EPODE International Network (1,575 words) [view diff] exact match in snippet view article find links to article

(August 17, 2004). "Relationships between physical activity and plasma leptin levels in healthy children: the Fleurbaix–Laventie Ville Santé II Study"

ALOXE3 (2,593 words) [view diff] exact match in snippet view article find links to article

high-fat/high-sugar diet and in the db/db mouse, which overeats due to a mutation in the leptin receptor. In these mice, ALOXE3 overexpression stimulates higher basal thermogenesis

Circumventricular organs (4,299 words) [view diff] exact match in snippet view article find links to article

that the subfornical organ may be an important intermediary though which leptin acts to maintain blood pressure within normal physiological limits via descending

Mike Phillips (speech recognition) (1,368 words) [view diff] exact match in snippet view article

Dugan, Valarie; Hey, Patricia J.; Caskey, C. Thomas; Hess, J. Fred (1996). "Leptin receptor missense mutation in the fatty Zucker rat". Nature Genetics. 13

Thymic involution (2,206 words) [view diff] exact match in snippet view article find links to article

S.; Ghatei M.A.; Ritter M.A.; Lechler R.I.; Bloom S.R.; et al. (1999). "Leptin protects mice from starvation induced lymphoid atrophy and increases thymic

Depolarization-induced suppression of inhibition (1,780 words) [view diff] exact match in snippet view article find links to article

Chua SC Jr, Talmage DA, Role LW. (2005) Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit. Neuron. Dec 22;48(6):1055-66

Equine metabolic syndrome (3,020 words) [view diff] exact match in snippet view article find links to article

Other signs suggesting EMS include elevated blood triglyceride levels and leptin levels, hypertension, and reproductive changes in mares (an increased diestrus

Prenatal stress (4,478 words) [view diff] exact match in snippet view article find links to article

"Prenatal stress and infants' development: association with cortisol and leptin levels in cord blood and saliva" (PDF). Physiology and Pharmacology. 24

Apolipoprotein D (4,897 words) [view diff] exact match in snippet view article find links to article

Leibowitz SF (May 2001). "Apolipoprotein D interacts with the long-form leptin receptor: a hypothalamic function in the control of energy homeostasis"

TM5441 (265 words) [view diff] exact match in snippet view article find links to article

Suppresses High Fat Diet-Induced Weight Gain via Alleviation of Hypothalamic Leptin Resistance". Frontiers in Pharmacology. 11: 943. doi:10.3389/fphar.2020

International Student Congress Of (bio)Medical Sciences (823 words) [view diff] exact match in snippet view article

their importance in vaccine research 2022 Prof. Jeffrey M. Friedman MD PhD Leptin and the regulation of food intake and body weight 2022 Prof. Karl Deisseroth

Instituto Gulbenkian de Ciência (3,978 words) [view diff] exact match in snippet view article find links to article

Henning (September 2015). "Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis". Cell. 163 (1): 84–94. doi:10.1016/j.cell.2015.08.055

Android fat distribution (3,258 words) [view diff] exact match in snippet view article find links to article

Atluri, R; Chaiken, RL; Lebovitz, HE (1999). "Body composition visceral fat, leptin and insulin resistance in Asian Indian Men". J Clin Endocrinol Metab. 84

Wendy Chung (3,482 words) [view diff] exact match in snippet view article find links to article

research to humans. In this research, Chung was able to clone a rodent gene (leptin receptor) leading to obesity and regulation of body weight. Her later work

Chorionic gonadotropin beta (2,381 words) [view diff] exact match in snippet view article find links to article

extracellular-regulated kinase (ERK) and AKT signals, and the instigation of leptin production by CGB requires a dialogue between cAMP and p38 signaling pathways

List of drugs granted breakthrough therapy designation (180 words) [view diff] exact match in snippet view article find links to article

proopiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency Pralsetinib Blueprint Medicines Corp RET-mutant

Maria (given name) (22,612 words) [view diff] exact match in snippet view article

1984), Spanish actress Maria Leontieva (1792–1874), Russian pedagogue Maria Leptin, German developmental biologist and immunologist Maria Letonmäki (1882–1937)

O-GlcNAc (12,376 words) [view diff] exact match in snippet view article find links to article

O-GlcNAc Transferase That Act In Vivo Implicate Decreased O-GlcNAc Levels in Leptin-Mediated Nutrient Sensing". Angewandte Chemie International Edition. 57

Ghrelin O-acyltransferase (2,141 words) [view diff] exact match in snippet view article find links to article

appetite related hormones. For example, research has shown that the hormone leptin increases ghrelin O-acyl transferase mRNA levels, and therefore enzyme expression

Kim Dale (1,709 words) [view diff] exact match in snippet view article find links to article

L. J. (2018) Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice. Scientific Reports 8, Article number: 55 doi/10

Alexander Woodman (3,303 words) [view diff] exact match in snippet view article find links to article

homozygous sickle cell anemia. - Investigating genetic variants in the leptin gene related to obesity. - Studying the effects of post-diagnosis exercise