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Longer titles found: Mitochondrial unfolded protein response (view)

searching for Unfolded protein response 170 found (230 total)

alternate case: unfolded protein response

CREBL1 (854 words) [view diff] exact match in snippet view article find links to article

transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response". Biochem. J. 355 (Pt 1): 19–28. doi:10.1042/0264-6021:3550019

EIF2AK3 (1,365 words) [view diff] no match in snippet view article find links to article

"Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response". Nature Cell Biology. 2 (6): 326–332. doi:10.1038/35014014. PMID 10854322

HERPUD1 (1,033 words) [view diff] exact match in snippet view article find links to article

expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated

EIF2S1 (1,448 words) [view diff] exact match in snippet view article find links to article

essential for translational regulation and cell survival during the unfolded protein response". Molecular Cell. 5 (5): 897–904. doi:10.1016/S1097-2765(00)80330-5

2-Deoxy-D-glucose (1,079 words) [view diff] case mismatch in snippet view article find links to article

cells and other systems, and as such induces ER stress and the Unfolded Protein Response (UPR) pathway. 2-DG has been used as a targeted optical imaging

SIL1 (1,454 words) [view diff] exact match in snippet view article find links to article

protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren

Membrane-bound transcription factor site-1 protease (342 words) [view diff] exact match in snippet view article find links to article

ATF6-mediated unfolded protein response membrane protein intracellular domain proteolysis lysosome organization endoplasmic reticulum unfolded protein response post-translational

DNAJB9 (787 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum cytoplasm Biological process IRE1-mediated unfolded protein response ubiquitin-dependent ERAD pathway immunoglobulin production response

Anne Bertolotti (1,340 words) [view diff] exact match in snippet view article find links to article

York, United States, making seminal discoveries in the mammalian unfolded protein response. In 2001, Bertolotti became an Inserm Associate Professor at Ecole

PTPN1 (2,731 words) [view diff] exact match in snippet view article find links to article

reticulum unfolded protein response regulation of intracellular protein transport positive regulation of IRE1-mediated unfolded protein response negative

PARP16 (100 words) [view diff] exact match in snippet view article find links to article

tubular network cytosol Biological process endoplasmic reticulum unfolded protein response protein auto-ADP-ribosylation response to unfolded protein protein

WFS1 (1,173 words) [view diff] exact match in snippet view article find links to article

maturation by protein folding negative regulation of ATF6-mediated unfolded protein response negative regulation of DNA-binding transcription factor activity

CREBRF (71 words) [view diff] exact match in snippet view article find links to article

Biological process negative regulation of endoplasmic reticulum unfolded protein response positive regulation of prolactin signaling pathway response to

EDEM1 (537 words) [view diff] exact match in snippet view article find links to article

(2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation". J. Cell Biol

Derlin-2 (472 words) [view diff] exact match in snippet view article find links to article

(2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation". J. Cell Biol

SERP1 (512 words) [view diff] exact match in snippet view article find links to article

development positive regulation of translation IRE1-mediated unfolded protein response positive regulation of growth hormone secretion glucose metabolic

Apoptosis regulator BAX (2,108 words) [view diff] exact match in snippet view article find links to article

pathway in absence of ligand positive regulation of IRE1-mediated unfolded protein response blood vessel remodeling positive regulation of neuron apoptotic

Derlin-3 (450 words) [view diff] exact match in snippet view article find links to article

(2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation". J. Cell Biol

Mir-346 microRNA precursor family (657 words) [view diff] exact match in snippet view article find links to article

Kapoor N, Fuller C, Collawn JF, Bebok Z (December 2011). "The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1)

Nerea Irigoyen (767 words) [view diff] exact match in snippet view article find links to article

Spanish authorities and the general public. Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection. PLoS

BZIP intron saccharomycetales (207 words) [view diff] exact match in snippet view article find links to article

pairing is released by cytoplasmic splicing upon induction of the unfolded protein response". Cell. 107 (1): 103–114. doi:10.1016/S0092-8674(01)00505-0. PMID 11595189

CREB3 (1,148 words) [view diff] exact match in snippet view article find links to article

of transcription from RNA polymerase II promoter involved in unfolded protein response viral process positive regulation of transcription by RNA polymerase

ATF3 (1,701 words) [view diff] exact match in snippet view article find links to article

DNA-templated positive regulation of gene expression PERK-mediated unfolded protein response positive regulation of transcription by RNA polymerase II negative

Bcl-2 homologous antagonist killer (2,602 words) [view diff] exact match in snippet view article find links to article

apoptotic process positive regulation of endoplasmic reticulum unfolded protein response establishment or maintenance of transmembrane electrochemical

VAPB (1,298 words) [view diff] exact match in snippet view article find links to article

regulation by host of viral genome replication endoplasmic reticulum unfolded protein response endoplasmic reticulum to Golgi vesicle-mediated transport response

GPR78 (391 words) [view diff] exact match in snippet view article find links to article

"The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9

ERO1L (988 words) [view diff] exact match in snippet view article find links to article

1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response". The Journal of Biological Chemistry. 275 (31): 23685–92. doi:10

SYVN1 (1,074 words) [view diff] exact match in snippet view article find links to article

ubiquitination retrograde protein transport, ER to cytosol IRE1-mediated unfolded protein response negative regulation of endoplasmic reticulum stress-induced intrinsic

HSPA13 (679 words) [view diff] exact match in snippet view article find links to article

ERAD pathway endoplasmic reticulum unfolded protein response cellular response to heat Unfolded Protein Response protein refolding chaperone cofactor-dependent

NCK1 (3,450 words) [view diff] exact match in snippet view article find links to article

increased by the excessive fat. This stress causes expression of the unfolded protein response pathway, which leads to a decrease in glucose tolerance and inactivation

HSPA14 (433 words) [view diff] case mismatch in snippet view article find links to article

fidelity response to unfolded protein cellular response to heat Unfolded Protein Response protein refolding chaperone cofactor-dependent protein refolding

CRELD2 (2,395 words) [view diff] exact match in snippet view article find links to article

Zhang, Yingmei (2021-02-22). "Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases". Nature Reviews. Cardiology. 18 (7):

DAB2IP (861 words) [view diff] exact match in snippet view article find links to article

regulation of synapse maturation positive regulation of IRE1-mediated unfolded protein response negative regulation of GTPase activity angiogenesis negative regulation

Robert Clarke (academic) (2,182 words) [view diff] exact match in snippet view article

and mitochondria, and reflects novel interactions within the unfolded protein response. His group has also identified interferon regulatory factor-1

DNAJB4 (489 words) [view diff] exact match in snippet view article find links to article

cytoplasm nucleoplasm plasma membrane Biological process response to unfolded protein response to heat protein folding positive regulation of ATP-dependent activity

HSPA6 (689 words) [view diff] case mismatch in snippet view article find links to article

cellular response to heat protein refolding neutrophil degranulation Unfolded Protein Response chaperone cofactor-dependent protein refolding Sources:Amigo /

CUL7 (737 words) [view diff] exact match in snippet view article find links to article

mitotic cytokinesis proteolysis vasculogenesis IRE1-mediated unfolded protein response positive regulation of dendrite morphogenesis protein ubiquitination

Calreticulin (2,452 words) [view diff] exact match in snippet view article find links to article

JA, Eyholzer M, Timchenko NA, Mueller BU, Pabst T (Jun 2010). "Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid

Galactosemic cataract (2,717 words) [view diff] exact match in snippet view article find links to article

subsequent accumulation of misfolded proteins in the ER activates the unfolded protein response (UPR) in LECs. In agreement, it was later observed on galactosemic

DNAJB11 (795 words) [view diff] exact match in snippet view article find links to article

reticulum chaperone complex Biological process IRE1-mediated unfolded protein response positive regulation of ATP-dependent activity protein folding

Danyelle Townsend (2,027 words) [view diff] exact match in snippet view article find links to article

identified S-glutathionylation as a cell stress indicator and unfolded protein response regulator, linking it to pathologies and potential therapies influenced

BZIP intron ascomycota (161 words) [view diff] exact match in snippet view article find links to article

Penttila M (2003). "Activation mechanisms of the HAC1-mediated unfolded protein response in filamentous fungi". Mol Microbiol. 47 (4): 1149–1161. doi:10

BZIP intron plant (229 words) [view diff] exact match in snippet view article find links to article

IRE1 of a mRNA encoding a transcription factor involved in the unfolded protein response in Arabidopsis". Proceedings of the National Academy of Sciences

YIF1A (1,710 words) [view diff] exact match in snippet view article find links to article

membrane delivery into dendrites. It also participates in ER unfolded protein response (UPR) by inducing ERN1/IRE1. Additionally, the YIF1A protein interacts

CTDSP2 (426 words) [view diff] exact match in snippet view article find links to article

protein phosphorylation protein dephosphorylation IRE1-mediated unfolded protein response regulation of transcription by RNA polymerase II dephosphorylation

EXTL3 (578 words) [view diff] exact match in snippet view article find links to article

Biological process positive regulation of cell growth IRE1-mediated unfolded protein response heparan sulfate proteoglycan biosynthetic process protein glycosylation

Tripeptidyl peptidase I (1,569 words) [view diff] exact match in snippet view article find links to article

proteolysis central nervous system development IRE1-mediated unfolded protein response protein catabolic process lysosome organization peptide catabolic

PLA2G4B (594 words) [view diff] exact match in snippet view article find links to article

process lipid metabolism lipid catabolic process IRE1-mediated unfolded protein response birth phosphatidylglycerol acyl-chain remodeling phospholipid

TSPYL2 (574 words) [view diff] exact match in snippet view article find links to article

Biological process cell cycle nucleosome assembly IRE1-mediated unfolded protein response negative regulation of cell cycle negative regulation of DNA replication

EDEM3 (468 words) [view diff] exact match in snippet view article find links to article

control compartment Biological process endoplasmic reticulum unfolded protein response protein glycosylation N-glycan processing response to unfolded

Hepatoma-derived growth factor (900 words) [view diff] exact match in snippet view article find links to article

collagen-containing extracellular matrix Biological process IRE1-mediated unfolded protein response cell population proliferation regulation of transcription, DNA-templated

EXTL1 (517 words) [view diff] exact match in snippet view article find links to article

reticulum membrane Biological process skeletal system development protein glycosylation IRE1-mediated unfolded protein response Sources:Amigo / QuickGO

Meesmann corneal dystrophy (1,263 words) [view diff] exact match in snippet view article find links to article

John (2016-01-11). "Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy". Human

EDEM2 (418 words) [view diff] exact match in snippet view article find links to article

control compartment Biological process endoplasmic reticulum unfolded protein response mannose trimming involved in glycoprotein ERAD pathway N-glycan

HSPA2 (901 words) [view diff] case mismatch in snippet view article find links to article

cell cycle vesicle-mediated transport cellular response to heat Unfolded Protein Response chaperone cofactor-dependent protein refolding Sources:Amigo /

GSK3A (212 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway protein phosphorylation IRE1-mediated unfolded protein response negative regulation of glucose import negative regulation of insulin

NFE2L2 (3,438 words) [view diff] exact match in snippet view article find links to article

response to fluid shear stress cell redox homeostasis PERK-mediated unfolded protein response positive regulation of glutathione biosynthetic process transcription

SEC63 (637 words) [view diff] exact match in snippet view article find links to article

reticulum Sec62/Sec63 complex Biological process IRE1-mediated unfolded protein response protein targeting to membrane liver development protein transport

DCTN1 (1,632 words) [view diff] exact match in snippet view article find links to article

vesicle-mediated transport transport along microtubule IRE1-mediated unfolded protein response retrograde transport, endosome to Golgi G2/M transition of mitotic

ATPase ASNA1 (427 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum GET complex Biological process IRE1-mediated unfolded protein response inorganic anion transport transport posttranslational protein

WIPI1 (408 words) [view diff] exact match in snippet view article find links to article

vesicle targeting, trans-Golgi to endosome autophagy IRE1-mediated unfolded protein response macroautophagy autophagy of mitochondrion protein lipidation protein

HSPA9 (1,300 words) [view diff] case mismatch in snippet view article find links to article

protein iron-sulfur cluster assembly cellular response to heat Unfolded Protein Response protein refolding regulation of erythrocyte differentiation chaperone

ERO1LB (597 words) [view diff] exact match in snippet view article find links to article

1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response". The Journal of Biological Chemistry. 275 (31): 23685–92. doi:10

Daz interacting zinc finger protein 3 (115 words) [view diff] exact match in snippet view article find links to article

protein polyubiquitination protein ubiquitination ubiquitin-dependent ERAD pathway endoplasmic reticulum unfolded protein response Sources:Amigo / QuickGO

ATP6V0D1 (667 words) [view diff] exact match in snippet view article find links to article

transport ion transport ion transmembrane transport IRE1-mediated unfolded protein response brain development cell projection organization regulation of macroautophagy

EXTL2 (493 words) [view diff] exact match in snippet view article find links to article

N-acetylglucosamine metabolic process UDP-N-acetylgalactosamine metabolic process IRE1-mediated unfolded protein response protein glycosylation Sources:Amigo / QuickGO

NFYC (1,101 words) [view diff] exact match in snippet view article find links to article

transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response". Mol. Cell. Biol. 21 (4): 1239–48. doi:10.1128/MCB.21.4.1239-1248

Cell division control protein 4 (1,874 words) [view diff] exact match in snippet view article find links to article

degradation-dependent events in S. cerevisiae like for instance unfolded protein response. In mammals, amongst others c-Myc, Src3, Cyclin E, and the Notch

PREB (431 words) [view diff] exact match in snippet view article find links to article

reticulum membrane Biological process protein transport IRE1-mediated unfolded protein response vesicle-mediated transport transcription, DNA-templated positive

KLHDC3 (482 words) [view diff] exact match in snippet view article find links to article

cytoplasm cytosol nucleoplasm Biological process reciprocal meiotic recombination IRE1-mediated unfolded protein response meiosis Sources:Amigo / QuickGO

CXXC1 (714 words) [view diff] exact match in snippet view article find links to article

positive regulation of transcription, DNA-templated IRE1-mediated unfolded protein response histone H3-K4 methylation regulation of transcription, DNA-templated

IGFBP1 (1,045 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum lumen Biological process PERK-mediated unfolded protein response tissue regeneration insulin receptor signaling pathway regulation

TEGT (575 words) [view diff] case mismatch in snippet view article find links to article

process negative regulation of calcium ion transport into cytosol negative regulation of RNA splicing Unfolded Protein Response Sources:Amigo / QuickGO

ZBTB17 (1,218 words) [view diff] exact match in snippet view article find links to article

with mouth forming second ectoderm development IRE1-mediated unfolded protein response negative regulation of cell cycle regulation of transcription

ACADVL (986 words) [view diff] exact match in snippet view article find links to article

process regulation of cholesterol metabolic process IRE1-mediated unfolded protein response fatty acid beta-oxidation temperature homeostasis fatty acid catabolic

DNAJC3 (1,492 words) [view diff] exact match in snippet view article find links to article

apoptotic process response to unfolded protein IRE1-mediated unfolded protein response defense response to virus proteolysis involved in cellular protein

Galactose-1-phosphate uridylyltransferase deficiency (1,280 words) [view diff] exact match in snippet view article find links to article

da-Silva WS, Montero-Lomelí M, Masuda CA (January 2014). "The unfolded protein response has a protective role in yeast models of classic galactosemia"

CREB3L1 (616 words) [view diff] exact match in snippet view article find links to article

DNA-templated multicellular organism development endoplasmic reticulum unfolded protein response response to unfolded protein osteoblast differentiation positive

Class A basic helix-loop-helix protein 15 (503 words) [view diff] exact match in snippet view article find links to article

Cellular component nucleus Biological process endoplasmic reticulum unfolded protein response cell-cell signaling G protein-coupled receptor signaling pathway

PTPN2 (1,202 words) [view diff] exact match in snippet view article find links to article

receptor signaling pathway positive regulation of PERK-mediated unfolded protein response dephosphorylation negative regulation of interleukin-4-mediated

SRPRB (612 words) [view diff] exact match in snippet view article find links to article

intracellular anatomical structure endoplasmic reticulum membrane Biological process IRE1-mediated unfolded protein response Sources:Amigo / QuickGO

Srp receptor alpha subunit (138 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum membrane Biological process IRE1-mediated unfolded protein response intracellular protein transport cotranslational protein targeting

Pardaxin (927 words) [view diff] exact match in snippet view article find links to article

(ROS). ROS production disrupts protein folding and induces the unfolded protein response (UPR). This causes stress on the endoplasmic reticulum, which

GOSR2 (803 words) [view diff] exact match in snippet view article find links to article

membrane Biological process COPII vesicle coating IRE1-mediated unfolded protein response protein transport vesicle-mediated transport Golgi to vacuole

SSR1 (790 words) [view diff] exact match in snippet view article find links to article

membrane endoplasmic reticulum Biological process IRE1-mediated unfolded protein response cotranslational protein targeting to membrane positive regulation

Death-associated protein 6 (1,528 words) [view diff] case mismatch in snippet view article find links to article

protein kinase activity apoptotic process cellular response to heat Unfolded Protein Response cellular response to cadmium ion cellular response to copper ion

AGR2 (3,024 words) [view diff] exact match in snippet view article find links to article

PERK-mediated unfolded protein response response to endoplasmic reticulum stress positive regulation of IRE1-mediated unfolded protein response positive regulation

HSP90B1 (1,487 words) [view diff] exact match in snippet view article find links to article

regulation of phosphoprotein phosphatase activity ATF6-mediated unfolded protein response actin rod assembly retrograde protein transport, ER to cytosol

AMFR (1,117 words) [view diff] exact match in snippet view article find links to article

human ageing protein polyubiquitination endoplasmic reticulum unfolded protein response protein K48-linked ubiquitination protein complex oligomerization

HSPB8 (1,282 words) [view diff] case mismatch in snippet view article find links to article

cellular response to heat biological process protein phosphorylation Unfolded Protein Response positive regulation of aggrephagy Sources:Amigo / QuickGO

KDELR3 (534 words) [view diff] exact match in snippet view article find links to article

protein transport protein retention in ER lumen IRE1-mediated unfolded protein response vesicle-mediated transport retrograde vesicle-mediated transport

GFPT1 (886 words) [view diff] exact match in snippet view article find links to article

process circadian regulation of gene expression IRE1-mediated unfolded protein response glutamine metabolic process UDP-N-acetylglucosamine biosynthetic

Breakthrough Prize in Life Sciences (351 words) [view diff] exact match in snippet view article find links to article

Walter (b. 1954) Germany United States "for elucidating the unfolded protein response, a cellular quality-control system that detects disease-causing

Calnexin (2,214 words) [view diff] exact match in snippet view article find links to article

regulates a subset of endoplasmic reticulum chaperone genes in the unfolded protein response". Mol Cell Biol. 23 (21): 5448–59. doi:10.1128/mcb.23.21.7448-7459

Calcium signaling (2,271 words) [view diff] exact match in snippet view article find links to article

ER stress is also related to Ca2+ signaling and along with the unfolded protein response, can cause ER associated degradation (ERAD) and autophagy. Astrocytes

PPP2R5B (1,109 words) [view diff] exact match in snippet view article find links to article

regulation of DNA-binding transcription factor activity IRE1-mediated unfolded protein response negative regulation of G0 to G1 transition positive regulation

TMEM241 (855 words) [view diff] exact match in snippet view article find links to article

In another case TMEM241 was found to be upregulated during the unfolded protein response following the overexpression of Ero1α (Endoplasmic Reticulum oxidoreduclin

Nucleobindin 1 (1,024 words) [view diff] exact match in snippet view article find links to article

Tomida A, Kitahara O, et al. (2007). "Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation". J. Biol. Chem. 282 (40): 29264–72

ATF4 (1,894 words) [view diff] exact match in snippet view article find links to article

expression response to endoplasmic reticulum stress PERK-mediated unfolded protein response response to manganese-induced endoplasmic reticulum stress positive

SULT1A3 (905 words) [view diff] exact match in snippet view article find links to article

cytosol Biological process steroid metabolic process IRE1-mediated unfolded protein response catecholamine metabolic process sulfation lipid metabolism flavonoid

Optineurin (1,202 words) [view diff] case mismatch in snippet view article find links to article

positive regulation of xenophagy positive regulation of autophagy Unfolded Protein Response Golgi ribbon formation immune system process innate immune response

CDK5RAP3 (870 words) [view diff] exact match in snippet view article find links to article

mediator regulation of phosphatase activity endoplasmic reticulum unfolded protein response mitotic G2/M transition checkpoint brain development apoptotic

Porcine reproductive and respiratory syndrome virus 2 (2,788 words) [view diff] exact match in snippet view article find links to article

space via exocytosis. The type 2 PRRSV infection induces the unfolded protein response (UPR) within the cell, also known as the endoplasmic reticulum

Protein disulfide-isomerase (1,936 words) [view diff] case mismatch in snippet view article find links to article

Perri ER, Thomas CJ, Parakh S, Spencer DM, Atkin JD (2016). "The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration"

SEC31A (873 words) [view diff] exact match in snippet view article find links to article

membrane cytosol COPII vesicle coat Biological process IRE1-mediated unfolded protein response response to calcium ion COPII vesicle coating vesicle-mediated

Lipogenesis (2,179 words) [view diff] case mismatch in snippet view article find links to article

Iván; Tovar-Palacio, Claudia (2021-01-07). "The Role of the Unfolded Protein Response on Renal Lipogenesis in C57BL/6 Mice". Biomolecules. 11 (1): 73

DDX11 (634 words) [view diff] exact match in snippet view article find links to article

complex Biological process sister chromatid cohesion IRE1-mediated unfolded protein response viral process nucleobase-containing compound metabolic process

PPP1R15A (1,396 words) [view diff] exact match in snippet view article find links to article

alpha dephosphorylation negative regulation of PERK-mediated unfolded protein response regulation of translation apoptotic process response to endoplasmic

SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article

Fc-epsilon receptor signaling pathway heart development IRE1-mediated unfolded protein response regulation of cell population proliferation angiogenesis regulation

SHC1 (1,641 words) [view diff] exact match in snippet view article find links to article

Fc-epsilon receptor signaling pathway heart development IRE1-mediated unfolded protein response regulation of cell population proliferation angiogenesis regulation

Vitiligo (3,728 words) [view diff] exact match in snippet view article find links to article

necessary for protein folding, so skin cells may initiate the unfolded protein response which releases cytokines, thus mounting an immune response The

STUB1 (1,473 words) [view diff] exact match in snippet view article find links to article

cellular response to DNA damage stimulus endoplasmic reticulum unfolded protein response positive regulation of ubiquitin-protein transferase activity

Buformin (2,257 words) [view diff] exact match in snippet view article find links to article

Shin-Ya K, et al. (May 2009). "Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation"

Barakat-Perenthaler syndrome (1,174 words) [view diff] exact match in snippet view article find links to article

protein, resulting in altered glycogen metabolism, upregulated unfolded protein response and premature neuronal differentiation which likely cause the

Receptor for activated C kinase 1 (2,598 words) [view diff] exact match in snippet view article find links to article

of cell migration negative regulation of endoplasmic reticulum unfolded protein response cellular response to growth factor stimulus negative regulation

SEC61B (905 words) [view diff] exact match in snippet view article find links to article

process retrograde protein transport, ER to cytosol IRE1-mediated unfolded protein response ubiquitin-dependent ERAD pathway protein transport intracellular

ADD1 (953 words) [view diff] exact match in snippet view article find links to article

embryonic development actin filament bundle assembly IRE1-mediated unfolded protein response transmembrane transport cell morphogenesis erythrocyte differentiation

CCL2 (2,415 words) [view diff] exact match in snippet view article find links to article

negative regulation of glial cell apoptotic process PERK-mediated unfolded protein response MAPK cascade positive regulation of calcium ion import cytoskeleton

NCK2 (1,551 words) [view diff] exact match in snippet view article find links to article

formation cell migration negative regulation of PERK-mediated unfolded protein response negative regulation of transcription from RNA polymerase II promoter

Sec14 (983 words) [view diff] exact match in snippet view article find links to article

dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast". Molecular Biology of the Cell. 19

UTP—glucose-1-phosphate uridylyltransferase (2,932 words) [view diff] exact match in snippet view article find links to article

brain, which leads to altered glycogen metabolism, upregulated unfolded protein response and premature neuronal differentiation. Other bi-allelic loss-of-function

COP9 constitutive photomorphogenic homolog subunit 5 (1,436 words) [view diff] exact match in snippet view article find links to article

transcription-coupled nucleotide-excision repair regulation of IRE1-mediated unfolded protein response positive regulation of transcription by RNA polymerase II translational

HYOU1 (1,051 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum to Golgi vesicle-mediated transport IRE1-mediated unfolded protein response response to ischemia cellular response to hypoxia negative regulation

Elongation factor for RNA polymerase II 2 (608 words) [view diff] exact match in snippet view article find links to article

factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response". J. Immunol. 193 (9): 4663–74. doi:10.4049/jimmunol.1401608.

Prelamin-A/C (2,694 words) [view diff] exact match in snippet view article find links to article

development regulation of protein localization to nucleus IRE1-mediated unfolded protein response mitotic nuclear membrane disassembly protein localization to nucleus

HSPA1B (1,959 words) [view diff] case mismatch in snippet view article find links to article

protein complex assembly positive regulation of RNA splicing Unfolded Protein Response positive regulation of erythrocyte differentiation chaperone cofactor-dependent

HSPA1L (2,317 words) [view diff] case mismatch in snippet view article find links to article

binding of sperm to zona pellucida cellular response to heat Unfolded Protein Response chaperone cofactor-dependent protein refolding Sources:Amigo /

HSF1 (2,447 words) [view diff] case mismatch in snippet view article find links to article

regulation of cell population proliferation cellular response to heat Unfolded Protein Response regulation of protein heterodimerization activity positive regulation

PACRG (1,027 words) [view diff] case mismatch in snippet view article find links to article

cilium mitochondrion nucleus Biological process negative regulation of cell death Unfolded Protein Response spermatid development Sources:Amigo / QuickGO

BCL2L11 (1,403 words) [view diff] exact match in snippet view article find links to article

dentin-containing tooth positive regulation of IRE1-mediated unfolded protein response positive regulation of cysteine-type endopeptidase activity involved

Interleukin 8 (2,761 words) [view diff] exact match in snippet view article find links to article

replication via double stranded DNA intermediate PERK-mediated unfolded protein response induction of positive chemotaxis chemotaxis regulation of cell

Ellen Jorgensen (1,495 words) [view diff] exact match in snippet view article find links to article

"Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells". BMC cancer. 8: 229

Lasker Award (1,545 words) [view diff] exact match in snippet view article find links to article

emergencies. 2014 Basic Kazutoshi Mori For discoveries concerning the unfolded protein response – an intracellular quality control system that detects harmful

TLN1 (2,835 words) [view diff] exact match in snippet view article find links to article

Biological process cell-substrate junction assembly IRE1-mediated unfolded protein response muscle contraction platelet degranulation platelet aggregation

KDELR1 (1,819 words) [view diff] exact match in snippet view article find links to article

stress and causes apoptosis of cells during the process of an unfolded protein response. Increase pressure load/mechanical stress in KDEL D193N mice caused

SELS (gene) (1,058 words) [view diff] exact match in snippet view article

overload response response to redox state endoplasmic reticulum unfolded protein response negative regulation of glucose import retrograde protein transport

Neurokinin A (2,873 words) [view diff] exact match in snippet view article find links to article

scenarios can result in calcium overload, protein degradation, the unfolded protein response or an accumulation of DNA damage. Endogenous cellular responses

Temozolomide (2,958 words) [view diff] exact match in snippet view article find links to article

Schönthal AH, Hofman FM, Chen TC, Lee AS (October 2007). "The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity

TEAD1 (4,077 words) [view diff] exact match in snippet view article find links to article

"Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation". Cell Death and Differentiation

Japanese encephalitis (3,592 words) [view diff] exact match in snippet view article find links to article

virus infection initiates endoplasmic reticulum stress and an unfolded protein response". J. Virol. 76 (9): 4162–71. doi:10.1128/JVI.76.9.4162-4171.2002

Kenneth Tew (2,305 words) [view diff] exact match in snippet view article find links to article

responses to drugs inducing endoplasmic reticulum stress and the unfolded protein response. His research has looked into the role of GTSP in cellular redox

HSPA1A (3,267 words) [view diff] case mismatch in snippet view article find links to article

protein complex assembly positive regulation of RNA splicing Unfolded Protein Response positive regulation of erythrocyte differentiation chaperone cofactor-dependent

Hana El-Samad (1,024 words) [view diff] exact match in snippet view article find links to article

the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response". PLOS Biology. 8 (7): e1000415. doi:10.1371/JOURNAL.PBIO.1000415

BOK (gene) (1,775 words) [view diff] exact match in snippet view article

apoptotic signaling pathway positive regulation of PERK-mediated unfolded protein response regulation of granulosa cell apoptotic process positive regulation

REEP5 (2,156 words) [view diff] exact match in snippet view article find links to article

2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation". The Journal of

HSPA8 (3,533 words) [view diff] case mismatch in snippet view article find links to article

vesicle-mediated transport cytokine-mediated signaling pathway cellular response to heat Unfolded Protein Response slow axonal transport Sources:Amigo / QuickGO

STC2 (1,326 words) [view diff] exact match in snippet view article find links to article

response to endoplasmic reticulum stress endoplasmic reticulum unfolded protein response decidualization regulation of store-operated calcium entry cellular

Endomembrane system (4,771 words) [view diff] no match in snippet view article find links to article

"Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response". Nature Cell Biology. 2 (6): 326–32. doi:10.1038/35014014. PMID 10854322

PIK3R1 (3,136 words) [view diff] exact match in snippet view article find links to article

of cell adhesion positive regulation of endoplasmic reticulum unfolded protein response epidermal growth factor receptor signaling pathway Fc-gamma receptor

EP300 (4,234 words) [view diff] exact match in snippet view article find links to article

of transcription from RNA polymerase II promoter involved in unfolded protein response fat cell differentiation positive regulation by host of viral

Bruce Beutler (12,100 words) [view diff] exact match in snippet view article find links to article

caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response". Proceedings of the National Academy of Sciences of the United

Fibroblast growth factor 21 (3,036 words) [view diff] exact match in snippet view article find links to article

low-density lipoprotein particle stimulus endoplasmic reticulum unfolded protein response negative regulation of neuron death positive regulation of triglyceride

Ze'ev Ronai (1,629 words) [view diff] exact match in snippet view article find links to article

of ubiquitin ligases in key cellular processes (i.e. hypoxia, unfolded protein response, mitochondrial dynamics, anti-tumor immunity) and their critical

Giovanna Mallucci (2,009 words) [view diff] exact match in snippet view article find links to article

Using mouse models, they described the pathogenic role of the unfolded protein response (UPR) in neurodegeneration, which led to the discovery of the

Shaw Prize (3,544 words) [view diff] case mismatch in snippet view article find links to article

States 2014 Kazutoshi Mori Japan For their discovery of the Unfolded Protein Response of the endoplasmic reticulum, a cell signalling pathway that controls

Cyclin D1 (5,694 words) [view diff] exact match in snippet view article find links to article

cellular response to DNA damage stimulus endoplasmic reticulum unfolded protein response protein phosphorylation regulation of G1/S transition of mitotic

C5orf24 (1,660 words) [view diff] exact match in snippet view article find links to article

"Gene expression profiling in tibial muscular dystrophy reveals unfolded protein response and altered autophagy". PLOS ONE. 9 (3): e90819. Bibcode:2014PLoSO

P53 upregulated modulator of apoptosis (3,387 words) [view diff] exact match in snippet view article find links to article

response to DNA damage stimulus positive regulation of IRE1-mediated unfolded protein response positive regulation of neuron apoptotic process apoptotic signaling

Interferon gamma (6,477 words) [view diff] exact match in snippet view article find links to article

regulation of transcription, DNA-templated endoplasmic reticulum unfolded protein response cell surface receptor signaling pathway positive regulation of

Wafik El-Deiry (3,588 words) [view diff] exact match in snippet view article find links to article

(2017-09-12). "Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP". Oncotarget. 8 (47):

Chromium(III) picolinate (5,087 words) [view diff] exact match in snippet view article

Kitamura, Masanori (2008). "Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces". American Journal of Physiology

Zihai Li (3,830 words) [view diff] exact match in snippet view article find links to article

demonstration of CNPY2 as a critical sensor for PERK-mediated unfolded protein response. "Pelotonia Institute for Immuno-Oncology Launched at Ohio State

Parkin (protein) (5,731 words) [view diff] case mismatch in snippet view article

macroautophagy negative regulation of canonical Wnt signaling pathway Unfolded Protein Response aggresome assembly proteasome-mediated ubiquitin-dependent protein

Richard I. Morimoto (4,168 words) [view diff] case mismatch in snippet view article find links to article

R.J. (2001). "Complementary Signaling Pathways Regulate the Unfolded Protein Response and Are Required for C. elegans Development". Cell. 107 (7): 893–903

SKIV2L (3,218 words) [view diff] exact match in snippet view article find links to article

the endogenous RNAs fail to be processed, the cell undergoes an unfolded protein response which triggers an antiviral interferon (IFN) response. Human cells

Valosin-containing protein (5,866 words) [view diff] exact match in snippet view article find links to article

catabolic process protein ubiquitination endoplasmic reticulum unfolded protein response endoplasmic reticulum stress-induced pre-emptive quality control

Heat shock protein 90kDa alpha (cytosolic), member A1 (8,175 words) [view diff] exact match in snippet view article

L, Neckers L (Dec 2002). "Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha". Molecular and Cellular Biology. 22

Mendel Lectures (857 words) [view diff] exact match in snippet view article find links to article

Walter HHMI / University of California, San Francisco, USA "The unfolded protein response in health and disease" 10 77 May 16, 2013 Stanislas Leibler Rockefeller

Cerebral organoid (6,605 words) [view diff] exact match in snippet view article find links to article

Intermediate progenitors seems to be particularly affected, due to the unfolded protein response pathway. It has also been observed that hypoxia resulted in apoptosis

Cluster of Excellence Frankfurt Macromolecular Complexes (15,449 words) [view diff] exact match in snippet view article find links to article

Wunnicke D, Hänelt I, Hummer G, Ernst R (2017). "Activation of the unfolded protein response by lipid bilayer stress". Mol Cell. 67 (4): 673–684.e8. doi:10