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searching for TLR2 38 found (90 total)

alternate case: tLR2

Damage-associated molecular pattern (3,562 words) [view diff] exact match in snippet view article find links to article

metabolism, they also act as DAMPs by interacting with their receptors (TLR2, TLR4, RAGE) after they are released from phagocytes. Mono- and polysaccharides:
K. Narayanaswamy Balaji (544 words) [view diff] exact match in snippet view article find links to article
corrects three (Source: Retraction Watch) 1. Withdrawal: Pathogen-specific TLR2 protein activation programs macrophages to induce Wnt-β-catenin signaling
Cell–cell recognition (2,035 words) [view diff] exact match in snippet view article find links to article
allows disease to develop rapidly. In particular, mutations in the genes for TLR2 and TLR4 have been frequently implicated in increased susceptibility to pathogens
N-Arachidonoyl dopamine (1,483 words) [view diff] exact match in snippet view article find links to article
TNF) and exogenous (i.e. bacterial derived LPS (TLR4 agonist) and FSL-1 (TLR2/6 agonist)) inflammatory mediators. It can increase the TRPV1-mediated release
Joyoti Basu (1,464 words) [view diff] exact match in snippet view article find links to article
between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages in Nature Immunology journal in 2007
Serum amyloid A1 (4,238 words) [view diff] exact match in snippet view article find links to article
SAA1-dependent cholesterol metabolism. Moreover, the Toll-like receptors TLR2 and TLR4 mediate SAA1-induced cytokine gene expression. The P2X7 purinergic
Tuberculosis vaccines (712 words) [view diff] exact match in snippet view article find links to article
tuberculosis in Malawi." The Lancet 348 (1996): 17–24. Print. Tyne, A. et al. "TLR2-targeted secreted proteins from Mycobacterium tuberculosis areprotective
Curli (1,412 words) [view diff] exact match in snippet view article find links to article
Curli's beta sheet structure acts on the innate immune system, activating the TLR2 (Toll-Like Receptor 2). This then causes a downstream response by a producing
Bacillus anthracis (4,539 words) [view diff] exact match in snippet view article find links to article
increase the macrophage internalization of B. anthracis spores. (a) CD14 and TLR2 work in close proximity to propagate the activation signal. Mac-1 starts
Polysaccharide peptide (236 words) [view diff] exact match in snippet view article find links to article
Martzen M, Standish LJ, Disis ML (2011). "Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T
Lipoarabinomannan (2,650 words) [view diff] exact match in snippet view article find links to article
recognition receptor present on macrophages, associate with toll-like receptor 2 (TLR2) is described to be a receptor for PILAM. Binding of PILAM to the receptor
Fetal bovine serum (1,407 words) [view diff] exact match in snippet view article find links to article
Chowdhury, P; Sacks, SH; Sheerin, NS (August 2006). "Toll-like receptors TLR2 and TLR4 initiate the innate immune response of the renal tubular epithelium
Solenoid protein domain (1,081 words) [view diff] exact match in snippet view article find links to article
the WD40 repeat domain of beta-TrCP (green), leucine-rich repeat domain of TLR2 (red), armadillo repeat domain of beta-catenin (blue), ankyrin repeat domain
Interleukin 23 (2,456 words) [view diff] exact match in snippet view article find links to article
PMID 16630024. Re F, Strominger JL (October 2001). "Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells". The Journal of
Acne (16,982 words) [view diff] exact match in snippet view article find links to article
toll-like receptors (TLRs), especially TLR2 and TLR4, is a core mechanism of acne-related skin inflammation. Activation of TLR2 and TLR4 by C. acnes leads to increased
Tretinoin (2,845 words) [view diff] exact match in snippet view article find links to article
Modlin RL (March 2005). "Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function". Journal of Immunology. 174 (5): 2467–70. doi:10
Interleukin-1 receptor associated kinase (3,628 words) [view diff] exact match in snippet view article find links to article
IRAK-1, called Mal/TIRAP. Mal/TIRAP has been specifically implicated in TLR2 and TLR4 mediated NF-κB signaling. In addition, it has been shown that IRAK-2
Mycoplasma hominis (1,711 words) [view diff] exact match in snippet view article find links to article
(September 2014). "A Potential Pathogenic Factor from Mycoplasma hominisis a TLR2-Dependent, Macrophage-Activating, P50-Related Adhesin". American Journal
Asya Rolls (1,723 words) [view diff] exact match in snippet view article find links to article
in neurogenesis and found that TLR2 and TLR4 play opposing roles in the proliferation of new hippocampal neurons. TLR2 seemed to promote neurogenesis
Protein tandem repeats (1,797 words) [view diff] exact match in snippet view article find links to article
the WD40 repeat domain of beta-TrCP (green), leucine-rich repeat domain of TLR2 (red), armadillo repeat domain of beta-catenin (blue), ankyrin repeat domain
Martin Sheldon (968 words) [view diff] exact match in snippet view article find links to article
endocrine function of bovine granulosa cells from ovarian dominant follicles via TLR2 and TLR4 pathways". Endocrinology. 154 (9): 3377–86. doi:10.1210/en.2013-1102
Helicobacter muridarum (405 words) [view diff] exact match in snippet view article find links to article
"A Commensal Helicobacter sp. of the Rodent Intestinal Flora Activates TLR2 and NOD1 Responses in Epithelial Cells". PLOS ONE. 4 (4): e5396. Bibcode:2009PLoSO
Dawn Bowdish (1,754 words) [view diff] exact match in snippet view article find links to article
Leifer, C. A.; Tryggvason, K.; Gordon, S.; Russell, D. G. (2009). "MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial
Trefoil factor 3 (1,634 words) [view diff] exact match in snippet view article find links to article
Podolsky DK, Gerken G, Eyking A, Cario E (2009). "Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency". Gastroenterology
Leptospirosis (7,506 words) [view diff] exact match in snippet view article find links to article
directed against the LPS. Leptospira LPS only activates toll-like receptor 2 (TLR2) in monocytes in humans. The lipid A molecule of the bacteria is not recognised
Cord factor (3,760 words) [view diff] exact match in snippet view article find links to article
cytokines as well. However, there is also evidence that toll-like receptor 2 (TLR2) in conjunction with the protein MyD-88 is responsible for cytokine production
Heat shock protein (4,684 words) [view diff] exact match in snippet view article find links to article
(DAMPs). They are able to interact with pattern recognition receptors like TLR2 or TLR4 and activate antigen presenting cells by upregulation of co-stimulation
Signal transduction (7,544 words) [view diff] exact match in snippet view article find links to article
"Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4". Nature. 420 (6913): 324–9. Bibcode:2002Natur.420..324Y. doi:10
LYN (3,767 words) [view diff] exact match in snippet view article find links to article
(Jan 2016). "Lyn delivers bacteria to lysosomes for eradication through TLR2-initiated autophagy related phagocytosis". PLOS Pathogens. 12 (1): e1005363
Neutrophil extracellular traps (2,813 words) [view diff] exact match in snippet view article find links to article
products, TLR4-activated platelets, or complement proteins in tandem with TLR2 ligands." Vital NETosis is made possible through the blebbing of the nucleus
Melioidosis (7,497 words) [view diff] exact match in snippet view article find links to article
the immune system are activated by the host toll-like receptors such as TLR2, TLR4, and TLR5 that recognize the conserved pieces of the bacteria such
Cation-dependent mannose-6-phosphate receptor (1,325 words) [view diff] exact match in snippet view article find links to article
aeruginosa-induced cytokine production in human monocytes by mannose receptor and TLR2". Eur. J. Immunol. 39 (3): 730–40. doi:10.1002/eji.200838872. PMID 19197942
Gap junction (8,042 words) [view diff] exact match in snippet view article find links to article
PMID 19966054. Ey B, Eyking A, Gerken G, Podolsky DK, Cario E (August 2009). "TLR2 mediates gap junctional intercellular communication through connexin-43 in
Bernd Schröppel (1,055 words) [view diff] exact match in snippet view article find links to article
Zang W, S Heeger P, Bromberg JS, Murphy B, Schröppel B. Islet-expressed TLR2 and TLR4 sense injury and mediate early graft failure after transplantation
Proteolipid (2,445 words) [view diff] exact match in snippet view article find links to article
While LPS is detected by the toll-like receptor TLR4, LPs are detected by TLR2. Myelin proteolipid protein  This article incorporates text by Jessica Hutchinson
Adeno-associated virus (8,197 words) [view diff] exact match in snippet view article find links to article
indicate that AAV vectors interact with the Toll-like receptor (TLR)9- and TLR2-MyD88 pathways to trigger the innate immune response by stimulating the production
Role of microglia in disease (5,042 words) [view diff] exact match in snippet view article find links to article
the blood–brain barrier. Microglia interact with streptococcus via their TLR2 receptor; this interaction then activates microglia to produce nitric oxide
Francisco J. Quintana (1,806 words) [view diff] exact match in snippet view article find links to article
F., *Quintana F.J., Gandhi, R., Izquierdo, G., Lucas, M. & Weiner, H.L. TLR2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation