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Longer titles found: Minor spliceosome (view)

searching for Spliceosome 268 found (454 total)

alternate case: spliceosome

SNRPA1 (765 words) [view diff] exact match in snippet view article find links to article

specifically blocks the entry of U4/U6.U5 small nuclear ribonucleoprotein in spliceosome assembly". Journal of Virology. 67 (8): 4769–76. doi:10.1128/JVI.67.8
SNRPG (1,108 words) [view diff] exact match in snippet view article find links to article
Grigorieff N, Moore MJ (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
Small nuclear ribonucleoprotein polypeptide F (968 words) [view diff] exact match in snippet view article find links to article
Moore MJ (April 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
SNRPB2 (829 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
SNRPB (1,164 words) [view diff] exact match in snippet view article find links to article
MT, Reed R, Leder P (1998). "WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the
SF3B2 (1,455 words) [view diff] exact match in snippet view article find links to article
pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the
CDC5L (1,352 words) [view diff] exact match in snippet view article find links to article
progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required
DDX5 (1,548 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
SNRPD3 (1,164 words) [view diff] exact match in snippet view article find links to article
Grigorieff N, Moore MJ (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
Small nuclear ribonucleoprotein polypeptide E (1,093 words) [view diff] exact match in snippet view article find links to article
Moore MJ (April 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
Small nuclear ribonucleoprotein D2 (1,233 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
XAB2 (349 words) [view diff] exact match in snippet view article find links to article
Grigorieff N, Moore MJ (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
SF3A1 (1,216 words) [view diff] exact match in snippet view article find links to article
"Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114". Proc. Natl. Acad. Sci. U.S.A
RBM15 (573 words) [view diff] exact match in snippet view article find links to article
vessel morphogenesis ventricular septum morphogenesis mRNA splicing, via spliceosome placenta blood vessel development GO:0022415 viral process negative regulation
PPIH (572 words) [view diff] exact match in snippet view article find links to article
that mediates the interactions between different proteins inside the spliceosome. GRCh38: Ensembl release 89: ENSG00000171960 - Ensembl, May 2017 GRCm38:
DHX38 (816 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
CWC15 (481 words) [view diff] exact match in snippet view article find links to article
CWC15, AD002, C11orf5, Cwf15, HSPC148, ORF5, CWC15 spliceosome-associated protein, CWC15 spliceosome associated protein homolog External IDs MGI: 1913320
SF3B3 (1,212 words) [view diff] exact match in snippet view article find links to article
pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L
SF3A2 (995 words) [view diff] exact match in snippet view article find links to article
Bennett M, Reed R (October 1993). "Correspondence between a mammalian spliceosome component and an essential yeast splicing factor". Science. 262 (5130):
RBMX (1,314 words) [view diff] exact match in snippet view article find links to article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
BCAS2 (570 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529. S2CID 585778
Small nuclear ribonucleoprotein D1 (1,514 words) [view diff] exact match in snippet view article find links to article
complex U2-type precatalytic spliceosome U2-type catalytic step 2 spliceosome Biological process mRNA splicing, via spliceosome RNA processing mRNA processing
FUSIP1 (1,020 words) [view diff] exact match in snippet view article find links to article
splicing, via spliceosome mRNA splice site selection mRNA export from nucleus RNA splicing regulation of mRNA splicing, via spliceosome cytosolic transport
PRPF40B (162 words) [view diff] exact match in snippet view article find links to article
prespliceosome nucleus Biological process mRNA splicing, via spliceosome mRNA processing RNA splicing mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
WDR57 (804 words) [view diff] exact match in snippet view article find links to article
nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger
SNW1 (1,441 words) [view diff] exact match in snippet view article find links to article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
SF3A3 (1,017 words) [view diff] exact match in snippet view article find links to article
"Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114". Proc Natl Acad Sci U S A. 91
RBM8A (1,257 words) [view diff] exact match in snippet view article find links to article
PMID 11042152. Le Hir H, Izaurralde E, Maquat LE, Moore MJ (2001). "The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon
RBM17 (516 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529. S2CID 585778
SFRS6 (820 words) [view diff] exact match in snippet view article find links to article
alternative mRNA splicing, via spliceosome mRNA export from nucleus negative regulation of mRNA splicing, via spliceosome regulation of wound healing mRNA
SF3B1 (1,664 words) [view diff] exact match in snippet view article find links to article
pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical,
SRRM2 (912 words) [view diff] exact match in snippet view article find links to article
Grigorieff N, Moore MJ (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
DEAD box (1,441 words) [view diff] exact match in snippet view article find links to article
in the figure, DEAD box proteins are needed in the initial steps of spliceosome formation, while DEAH box proteins are indirectly required for the transesterifications
HNRNPL (1,071 words) [view diff] exact match in snippet view article find links to article
splicing, via spliceosome mRNA processing RNA processing RNA metabolic process regulation of alternative mRNA splicing, via spliceosome circadian rhythm
BAT1 (1,064 words) [view diff] exact match in snippet view article find links to article
Spliceosome RNA helicase BAT1 is an enzyme that in humans is encoded by the BAT1 gene. This gene encodes a member of the DEAD box family of RNA-dependent
RBM22 (637 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
SFRS3 (931 words) [view diff] exact match in snippet view article find links to article
splicing, via spliceosome mRNA export from nucleus mRNA transport mRNA processing RNA splicing regulation of mRNA splicing, via spliceosome RNA export from
SF3B4 (1,349 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nature Genetics. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529
EFTUD2 (1,336 words) [view diff] exact match in snippet view article find links to article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
Survival motor neuron domain containing 1 (498 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529. S2CID 585778
SF3B14 (909 words) [view diff] exact match in snippet view article find links to article
and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing
LSM3 (881 words) [view diff] exact match in snippet view article find links to article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
WBP11 (844 words) [view diff] exact match in snippet view article find links to article
division. Other studies have shown that Wbp11 is a component of the spliceosome. Also, that Wbp11 fragments block pre-mRNA splicing catalysis. Wbp11
SF3B5 (362 words) [view diff] exact match in snippet view article find links to article
complex spliceosomal complex precatalytic spliceosome nucleus U2 snRNP nucleoplasm U2-type precatalytic spliceosome Biological process mRNA processing RNA
Small nuclear ribonucleoprotein polypeptide A (1,068 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nature Genetics. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529
Usha Vijayaraghavan (600 words) [view diff] exact match in snippet view article find links to article
the spliceosome whose assembly is necessary for the two pre-mRNA splicing reactions. They use genetic and biochemical approaches to study spliceosome assembly
CACTIN (440 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
HNRNPC (1,576 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
DDX3Y (865 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
TRA2B (1,016 words) [view diff] exact match in snippet view article find links to article
splicing, via spliceosome embryonic brain development mRNA splicing, via spliceosome positive regulation of mRNA splicing, via spliceosome regulation of
Serine/arginine-rich splicing factor 1 (2,565 words) [view diff] exact match in snippet view article find links to article
regulation of RNA splicing transport regulation of alternative mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
ALYREF (1,261 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
PTBP1 (1,418 words) [view diff] exact match in snippet view article find links to article
via spliceosome mRNA processing negative regulation of mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome negative
U2 small nuclear RNA auxiliary factor 1 (1,782 words) [view diff] exact match in snippet view article find links to article
recognizing and binding to AG nucleotides at the 3’ splice site to facilitate spliceosome assembly. Alternatively spliced transcript variants encoding different
SFRS9 (1,035 words) [view diff] exact match in snippet view article find links to article
splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing negative regulation of mRNA splicing, via spliceosome mRNA splice
LSM2 (1,316 words) [view diff] exact match in snippet view article find links to article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
RNPS1 (1,238 words) [view diff] exact match in snippet view article find links to article
PMID 10449421. Le Hir H, Izaurralde E, Maquat LE, Moore MJ (Dec 2000). "The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon
HNRNPA2B1 (1,894 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
SFRS4 (913 words) [view diff] exact match in snippet view article find links to article
splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing negative regulation of mRNA splicing, via spliceosome mRNA 3'-end
PPM1G (650 words) [view diff] exact match in snippet view article find links to article
splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase
HNRNPA1 (1,813 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
NHP2L1 (924 words) [view diff] exact match in snippet view article find links to article
ribosomal subunit precatalytic spliceosome box C/D RNP complex U4atac snRNP protein-containing complex U2-type precatalytic spliceosome ribonucleoprotein complex
SMU1 (478 words) [view diff] exact match in snippet view article find links to article
spliceosome Biological process regulation of alternative mRNA splicing, via spliceosome mRNA processing RNA splicing mRNA splicing, via spliceosome Sources:Amigo
CUGBP Elav-like family member 4 (430 words) [view diff] exact match in snippet view article find links to article
via spliceosome alternative mRNA splicing, via spliceosome mRNA splice site selection regulation of alternative mRNA splicing, via spliceosome negative
SRRM1 (949 words) [view diff] exact match in snippet view article find links to article
PMID 10908574. Le Hir H, Izaurralde E, Maquat LE, Moore MJ (2000). "The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon
TEP1 (729 words) [view diff] exact match in snippet view article find links to article
cytoplasm nuclear matrix chromosome U5 snRNP precatalytic spliceosome catalytic step 2 spliceosome ribonucleoprotein complex Biological process telomere maintenance
PPIL1 (606 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
DBR1 (440 words) [view diff] exact match in snippet view article find links to article
RNA-dependent ATPase required for release of lariat-intron from the spliceosome". J. Biol. Chem. 277 (20): 17743–50. doi:10.1074/jbc.M200762200. PMID 11886864
Transcription elongation regulator 1 (1,194 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
SFRS5 (889 words) [view diff] exact match in snippet view article find links to article
nucleus cytosol nuclear speck Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing mRNA export
MAGOH (1,133 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
MFAP1 (394 words) [view diff] exact match in snippet view article find links to article
spliceosomal complex U2-type precatalytic spliceosome Biological process biological process mRNA splicing, via spliceosome mRNA processing RNA splicing Sources:Amigo
LSM7 (798 words) [view diff] exact match in snippet view article find links to article
tri-snRNP complex U2-type precatalytic spliceosome Lsm2-8 complex Biological process mRNA splicing, via spliceosome RNA processing mRNA processing exonucleolytic
WDR83 (408 words) [view diff] exact match in snippet view article find links to article
of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. GRCh38:
RNA Helicase A (1,645 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
HNRPU (1,287 words) [view diff] exact match in snippet view article find links to article
component CRD-mediated mRNA stability complex cytoplasm catalytic step 2 spliceosome membrane nucleoplasm telomerase holoenzyme complex cytoplasmic ribonucleoprotein
TXNL4A (504 words) [view diff] exact match in snippet view article find links to article
U2-type precatalytic spliceosome Biological process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome cell cycle mRNA processing
PPIE (gene) (1,044 words) [view diff] exact match in snippet view article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
TPM4 (610 words) [view diff] exact match in snippet view article find links to article
WY (2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo". Mol. Cell. Biol. 24 (20):
IK (gene) (304 words) [view diff] exact match in snippet view article
complex chromosome cytoplasm cytoskeleton nucleus U2-type precatalytic spliceosome Biological process GO:0007067 mitotic cell cycle mitotic spindle assembly
SYNCRIP (1,947 words) [view diff] exact match in snippet view article find links to article
EST-database searching allows characterization of the multi-protein spliceosome complex". Nature Genetics. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529
HNRNPR (1,422 words) [view diff] exact match in snippet view article find links to article
Moore MJ (April 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
WDR62 (982 words) [view diff] exact match in snippet view article find links to article
centrosome spindle pole cytoskeleton U5 snRNP precatalytic spliceosome catalytic step 2 spliceosome microtubule organizing center cytosol Biological process
DHX15 (443 words) [view diff] exact match in snippet view article find links to article
snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA. 10 (6): 929–41. doi:10.1261/rna.7320604. PMC 1370585. PMID 15146077
Messenger RNP (853 words) [view diff] exact match in snippet view article find links to article
7-methyl-guanosine capping enzymes. Later, the pre-mRNA is bound by the spliceosome containing exon and intron definition complexes and proteins and RNA
PPIL3 (650 words) [view diff] exact match in snippet view article find links to article
N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
LSM8 (742 words) [view diff] exact match in snippet view article find links to article
precatalytic spliceosome U2-type precatalytic spliceosome Lsm2-8 complex Biological process mRNA processing RNA splicing mRNA splicing, via spliceosome RNA metabolic
UBL5 (532 words) [view diff] exact match in snippet view article find links to article
Cellular component cytoplasm nucleus Biological process mRNA splicing, via spliceosome cellular protein modification process positive regulation of protein
HNRPA3 (463 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
RBM19 (500 words) [view diff] exact match in snippet view article find links to article
regulation of embryonic development regulation of alternative mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
HNRNPK (2,007 words) [view diff] exact match in snippet view article find links to article
component cytoplasm membrane focal adhesion nucleus catalytic step 2 spliceosome cell projection extracellular exosome podosome spliceosomal complex cell
SFSWAP (150 words) [view diff] exact match in snippet view article find links to article
regulation of mRNA splicing, via spliceosome regulation of transcription, DNA-templated alternative mRNA splicing, via spliceosome transcription, DNA-templated
RBM5 (815 words) [view diff] exact match in snippet view article find links to article
process mRNA splicing, via spliceosome RNA processing mRNA processing regulation of alternative mRNA splicing, via spliceosome spliceosomal complex assembly
SNIP1 (598 words) [view diff] exact match in snippet view article find links to article
Cellular component nucleoplasm nucleus cytosol U2-type precatalytic spliceosome Biological process positive regulation of protein targeting to mitochondrion
SKIV2L2 (727 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
RALY (602 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
TRA2A (603 words) [view diff] exact match in snippet view article find links to article
Biological process mRNA splicing, via spliceosome mRNA processing RNA splicing positive regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
SAP18 (701 words) [view diff] exact match in snippet view article find links to article
alternative mRNA splicing, via spliceosome transcription, DNA-templated negative regulation of mRNA splicing, via spliceosome RNA splicing positive regulation
SFRS2 (1,095 words) [view diff] exact match in snippet view article find links to article
alternative mRNA splicing, via spliceosome response to vitamin E regulation of RNA splicing mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
HNRPH1 (1,063 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
Gem-associated protein 6 (412 words) [view diff] exact match in snippet view article find links to article
nucleoplasm Gemini of coiled bodies Biological process mRNA splicing, via spliceosome mRNA processing spliceosomal complex assembly RNA splicing spliceosomal
DNAJB9 (695 words) [view diff] exact match in snippet view article find links to article
WY (2004). "The WW Domain-Containing Proteins Interact with the Early Spliceosome and Participate in Pre-mRNA Splicing In Vivo". Mol. Cell. Biol. 24 (20):
RBM4 (761 words) [view diff] exact match in snippet view article find links to article
arsenic-containing substance regulation of alternative mRNA splicing, via spliceosome cap-independent translational initiation circadian regulation of translation
Gem-associated protein 7 (478 words) [view diff] exact match in snippet view article find links to article
complex Gemini of coiled bodies Biological process mRNA splicing, via spliceosome mRNA processing RNA splicing spliceosomal snRNP assembly import into
THRAP3 (777 words) [view diff] exact match in snippet view article find links to article
transcription, DNA-templated positive regulation of mRNA splicing, via spliceosome rhythmic process mRNA processing intracellular steroid hormone receptor
Pinin (1,371 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
LSM6 (533 words) [view diff] exact match in snippet view article find links to article
ribonucleoprotein complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome Lsm2-8 complex Biological process tRNA processing mRNA processing RNA
SFRS12 (553 words) [view diff] exact match in snippet view article find links to article
Lamond AI, Mann M (2002). "Large-scale proteomic analysis of the human spliceosome". Genome Res. 12 (8): 1231–45. doi:10.1101/gr.473902. PMC 186633. PMID 12176931
ZCCHC8 (566 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
TFIP11 (672 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
DDX46 (615 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
SNRPN upstream reading frame protein (931 words) [view diff] exact match in snippet view article find links to article
component nucleus nuclear speck cytoplasm U5 snRNP catalytic step 2 spliceosome U4/U6 x U5 tri-snRNP complex spliceosomal complex U4 snRNP small nuclear
Small nuclear ribonucleoprotein polypeptide N (1,213 words) [view diff] exact match in snippet view article find links to article
binding RNA binding Cellular component cytoplasm U5 snRNP catalytic step 2 spliceosome U4/U6 x U5 tri-snRNP complex spliceosomal complex U4 snRNP small nuclear
PABPC1 (1,651 words) [view diff] exact match in snippet view article find links to article
Moore MJ (April 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
DDX42 (731 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis
PPP1R8 (1,222 words) [view diff] exact match in snippet view article find links to article
regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly". J. Biol. Chem. 277 (22): 19855–60. doi:10.1074/jbc.M200847200
CASC3 (886 words) [view diff] exact match in snippet view article find links to article
granule cell projection ribonucleoprotein complex U2-type catalytic step 1 spliceosome spliceosomal complex Biological process mRNA transport mRNA processing
Gem-associated protein 5 (658 words) [view diff] exact match in snippet view article find links to article
ribosomal subunit SMN-Gemin2 complex Biological process mRNA splicing, via spliceosome mRNA processing RNA splicing spliceosomal snRNP assembly import into
U4 (238 words) [view diff] exact match in snippet view article find links to article
spliceosomal RNA, a non-coding RNA component of the major U2-dependent spliceosome Haplogroup U4 (mtDNA), a human genetic group U4, unitary group of degree
Split gene theory (8,021 words) [view diff] exact match in snippet view article find links to article
spliceosome machinery was large and complex with ~300 proteins and several SnRNA molecules. The questions extended to the origin of the spliceosome.
DYRK1A (1,519 words) [view diff] exact match in snippet view article find links to article
mRNA splicing, via spliceosome nervous system development protein phosphorylation negative regulation of mRNA splicing, via spliceosome negative regulation
LSM5 (627 words) [view diff] exact match in snippet view article find links to article
U2-type precatalytic spliceosome Lsm2-8 complex Biological process nuclear-transcribed mRNA catabolic process mRNA splicing, via spliceosome mRNA processing
FRG1 (779 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
DYRK1A (1,519 words) [view diff] exact match in snippet view article find links to article
mRNA splicing, via spliceosome nervous system development protein phosphorylation negative regulation of mRNA splicing, via spliceosome negative regulation
U1 (285 words) [view diff] exact match in snippet view article find links to article
Statistics U1 spliceosomal RNA, a small nuclear RNA component of the spliceosome involved in pre-mRNA splicing. UI (disambiguation) 1U (disambiguation)
GTF2F2 (1,045 words) [view diff] exact match in snippet view article find links to article
transcription preinitiation complex Biological process mRNA splicing, via spliceosome regulation of transcription, DNA-templated transcription elongation from
LSM4 (728 words) [view diff] exact match in snippet view article find links to article
protein-containing complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome Lsm2-8 complex Biological process RNA processing mRNA processing spliceosomal
ZBTB7A (813 words) [view diff] exact match in snippet view article find links to article
transcription, DNA-templated regulation of alternative mRNA splicing, via spliceosome regulation of glycolytic process chromatin organization chromatin remodeling
HNRPF (1,020 words) [view diff] exact match in snippet view article find links to article
Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39
PRKG1 (1,307 words) [view diff] exact match in snippet view article find links to article
splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly". The EMBO Journal. 18 (16): 4549–59. doi:10.1093/emboj/18.16
MELK (975 words) [view diff] exact match in snippet view article find links to article
Keppens S, Van Eynde A, Rider MH, et al. (March 2004). "Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement
RNA binding motif protein, Y-linked, family 1, member A1 (877 words) [view diff] exact match in snippet view article find links to article
process mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
CDK13 (1,076 words) [view diff] exact match in snippet view article find links to article
proliferation GO:0022415 viral process alternative mRNA splicing, via spliceosome regulation of mitotic nuclear division transcription elongation from
HNRNPA0 (623 words) [view diff] exact match in snippet view article find links to article
nucleus ribonucleoprotein complex Biological process mRNA splicing, via spliceosome mRNA processing 3'-UTR-mediated mRNA stabilization inflammatory response
Small nuclear ribonucleoprotein polypeptide C (675 words) [view diff] exact match in snippet view article find links to article
prespliceosome Biological process spliceosomal snRNP assembly mRNA 5'-splice site recognition mRNA splicing, via spliceosome Sources:Amigo / QuickGO
NPM1 (1,797 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II negative regulation of mRNA splicing, via spliceosome protein stabilization protein homooligomerization regulation of cell
NOVA2 (96 words) [view diff] exact match in snippet view article find links to article
binding Cellular component nucleus Biological process mRNA splicing, via spliceosome regulation of RNA metabolic process negative regulation of cold-induced
GTF2F1 (1,487 words) [view diff] exact match in snippet view article find links to article
nucleus protein-containing complex Biological process mRNA splicing, via spliceosome regulation of transcription, DNA-templated transcription elongation from
HSPA8 (3,519 words) [view diff] exact match in snippet view article find links to article
complex Biological process chaperone-mediated autophagy mRNA splicing, via spliceosome late endosomal microautophagy regulation of transcription, DNA-templated
RAVER1 (336 words) [view diff] exact match in snippet view article find links to article
RNA binding GO:0001948 protein binding Cellular component nucleus cytoplasm Biological process mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Y box binding protein 1 (1,449 words) [view diff] exact match in snippet view article find links to article
Biological process CRD-mediated mRNA stabilization mRNA splicing, via spliceosome regulation of transcription, DNA-templated mRNA processing transcription
TXNL4B (378 words) [view diff] exact match in snippet view article find links to article
complex U4/U6 x U5 tri-snRNP complex Biological process mRNA splicing, via spliceosome cell cycle mRNA processing spliceosomal complex assembly RNA splicing
PRDX6 (1,257 words) [view diff] exact match in snippet view article find links to article
stress glycerophospholipid catabolic process cellular oxidant detoxification positive regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
RBPMS (660 words) [view diff] exact match in snippet view article find links to article
signal transduction response to oxidative stress mRNA splicing, via spliceosome positive regulation of nucleic acid-templated transcription Sources:Amigo
NUP98 (1,515 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II positive regulation of mRNA splicing, via spliceosome transcription by RNA polymerase II nucleocytoplasmic transport positive
Morpholino (4,328 words) [view diff] exact match in snippet view article find links to article
Thiele W, Müller F (November 2007). "Splicing segregation: the minor spliceosome acts outside the nucleus and controls cell proliferation". Cell. 131
TOE1 (428 words) [view diff] exact match in snippet view article find links to article
snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA. 10 (6): 929–41. doi:10.1261/rna.7320604. PMC 1370585. PMID 15146077
ACIN1 (641 words) [view diff] exact match in snippet view article find links to article
condensation mRNA processing negative regulation of mRNA splicing, via spliceosome RNA splicing positive regulation of apoptotic process positive regulation
Branchpoint Binding Protein (123 words) [view diff] exact match in snippet view article find links to article
Rymond, B. C. (2010). "The branchpoint binding protein: in and out of the spliceosome cycle". Adv Exp Med Biol. 693: 123–41. doi:10.1007/978-1-4419-7005-3_9
CPSF7 (417 words) [view diff] exact match in snippet view article find links to article
polyadenylation specificity factor complex Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing mRNA 3'-end
Diplonemidae (1,668 words) [view diff] exact match in snippet view article find links to article
contains a spliced leader RNA gene, which confirms their use of mRNA spliceosome-dependent trans splicing during nuclear expression. Diplonemids possess
METTL16 (135 words) [view diff] exact match in snippet view article find links to article
(adenine-N6)-methylation mRNA processing RNA splicing regulation of mRNA splicing, via spliceosome RNA methylation mRNA catabolic process S-adenosylmethionine biosynthetic
FAM172A (406 words) [view diff] exact match in snippet view article find links to article
cytoplasm Biological process regulation of alternative mRNA splicing, via spliceosome neural crest cell development mRNA processing RNA splicing heterochromatin
METTL14 (288 words) [view diff] exact match in snippet view article find links to article
Biological process stem cell population maintenance mRNA splicing, via spliceosome mRNA destabilization mRNA methylation RNA methylation mRNA catabolic
RBM11 (367 words) [view diff] exact match in snippet view article find links to article
to oxidative stress mRNA processing cell differentiation regulation of alternative mRNA splicing, via spliceosome RNA splicing Sources:Amigo / QuickGO
DAZ associated protein 1 (493 words) [view diff] exact match in snippet view article find links to article
proliferation cell differentiation positive regulation of mRNA splicing, via spliceosome spermatogenesis germ cell development Sources:Amigo / QuickGO
SWAP protein domain (425 words) [view diff] exact match in snippet view article find links to article
PMID 8206918. Clancy, Suzanne (2008). "RNA Splicing: Introns, Exons and Spliceosome". Nature Education. 1 (1). Retrieved 31 March 2011. Spikes DA, Kramer
RE1-silencing transcription factor (2,006 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II regulation of alternative mRNA splicing, via spliceosome response to hypoxia regulation of gene expression positive regulation
MBNL3 (409 words) [view diff] exact match in snippet view article find links to article
differentiation RNA splicing regulation of alternative mRNA splicing, via spliceosome regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
RBM7 (543 words) [view diff] exact match in snippet view article find links to article
nucleoplasm nucleolus nucleus Biological process GO:0007126 meiotic cell cycle regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Periannan Senapathy (4,083 words) [view diff] exact match in snippet view article find links to article
contained complex proteins, exactly as predicted by Senapathy's theory. The spliceosome is a highly complex machinery within the eukaryotic cell, containing
C9orf78 (509 words) [view diff] exact match in snippet view article find links to article
Cellular component nucleoplasm cytosol nucleus spliceosomal complex Biological process regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
STH (gene) (449 words) [view diff] exact match in snippet view article
component nucleus cytoplasm perinuclear region of cytoplasm Biological process positive regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
RNU2 (541 words) [view diff] exact match in snippet view article find links to article
WY (2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo". Mol. Cell. Biol. 24 (20):
CD2BP2 (589 words) [view diff] exact match in snippet view article find links to article
process negative regulation of phosphatase activity mRNA splicing, via spliceosome mRNA processing spliceosomal tri-snRNP complex assembly RNA splicing
KHDRBS1 (2,809 words) [view diff] exact match in snippet view article find links to article
mRNA splicing, via spliceosome spermatogenesis protein complex oligomerization regulation of alternative mRNA splicing, via spliceosome G1/S transition of
RBM25 (535 words) [view diff] exact match in snippet view article find links to article
process regulation of apoptotic process mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing Sources:Amigo / QuickGO
USP39 (496 words) [view diff] exact match in snippet view article find links to article
proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes". EMBO J. 20 (10): 2553–2563. doi:10.1093/emboj/20.10.2553. PMC 125249
PDCD7 (463 words) [view diff] exact match in snippet view article find links to article
snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA. 10 (6): 929–41. doi:10.1261/rna.7320604. PMC 1370585. PMID 15146077
POLR2A (1,325 words) [view diff] exact match in snippet view article find links to article
nucleus nucleoplasm cytoplasm Biological process mRNA splicing, via spliceosome regulation of transcription, DNA-templated somatic stem cell population
MBNL2 (422 words) [view diff] exact match in snippet view article find links to article
Biological process regulation of RNA splicing mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing Sources:Amigo / QuickGO
METTL3 (421 words) [view diff] exact match in snippet view article find links to article
processing adenosine to inosine editing RNA methylation mRNA splicing, via spliceosome mRNA catabolic process forebrain radial glial cell differentiation cellular
PQBP1 (2,884 words) [view diff] exact match in snippet view article find links to article
projection development alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome activation of innate immune response positive regulation
Drew Berry (984 words) [view diff] exact match in snippet view article find links to article
Motion" speaker series 2011– Cold Spring Harbor Laboratory's DNAi.org Spliceosome visualization 2012– Animations for E.O.Wilson's Life on Earth digital
GCFC2 (589 words) [view diff] exact match in snippet view article find links to article
negative regulation of transcription by RNA polymerase II transcription, DNA-templated RNA splicing mRNA splicing, via spliceosome Sources:Amigo / QuickGO
CIRBP (683 words) [view diff] exact match in snippet view article find links to article
UV positive regulation of translation negative regulation of translation positive regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
ELAV-like protein 2 (470 words) [view diff] exact match in snippet view article find links to article
binding Cellular component nucleoplasm Biological process regulation of transcription, DNA-templated mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Serrate RNA effector molecule homolog (507 words) [view diff] exact match in snippet view article find links to article
cell population maintenance primary miRNA processing mRNA splicing, via spliceosome snRNA transcription by RNA polymerase II mRNA processing Sources:Amigo
CCAR1 (549 words) [view diff] exact match in snippet view article find links to article
Biological process positive regulation of cell migration mRNA splicing, via spliceosome cell cycle regulation of transcription, DNA-templated transcription,
ELAV-like protein 1 (960 words) [view diff] exact match in snippet view article find links to article
stabilization 3'-UTR-mediated mRNA stabilization mRNA splicing, via spliceosome negative regulation of gene silencing by miRNA protein homooligomerization
CCDC55 (490 words) [view diff] exact match in snippet view article find links to article
splicing developmental process regulation of alternative mRNA splicing, via spliceosome nucleocytoplasmic transport mRNA processing Sources:Amigo / QuickGO
CSTF2T (718 words) [view diff] exact match in snippet view article find links to article
processing pre-mRNA cleavage required for polyadenylation mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA 3'-end processing
CSTF1 (689 words) [view diff] exact match in snippet view article find links to article
cleavage stimulating factor complex Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing mRNA 3'-end
SRPK2 (790 words) [view diff] exact match in snippet view article find links to article
organization phosphorylation mRNA processing regulation of mRNA splicing, via spliceosome protein phosphorylation spliceosomal complex assembly positive regulation
RBM3 (664 words) [view diff] exact match in snippet view article find links to article
regulation of translation response to cold negative regulation of translation positive regulation of mRNA splicing, via spliceosome Sources:Amigo / QuickGO
PCBP2 (1,252 words) [view diff] exact match in snippet view article find links to article
GO:0097481 postsynaptic density Biological process mRNA splicing, via spliceosome negative regulation of defense response to virus proteasome-mediated
DCPS (gene) (1,043 words) [view diff] exact match in snippet view article
nucleoplasm P-body cytosol Biological process mRNA cis splicing, via spliceosome negative regulation of programmed cell death mRNA processing nuclear-transcribed
DEK (gene) (1,023 words) [view diff] exact match in snippet view article
PMID 11058868. Le Hir H, Izaurralde E, Maquat LE, Moore MJ (2000). "The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon
SPEN (855 words) [view diff] exact match in snippet view article find links to article
signaling pathway positive regulation of neurogenesis mRNA splicing, via spliceosome GO:0022415 viral process negative regulation of transcription, DNA-templated
POLR2B (1,002 words) [view diff] exact match in snippet view article find links to article
core complex nucleus nucleoplasm Biological process mRNA splicing, via spliceosome somatic stem cell population maintenance transcription elongation from
POLR2H (986 words) [view diff] exact match in snippet view article find links to article
transcription initiation from RNA polymerase I promoter mRNA splicing, via spliceosome positive regulation of gene expression, epigenetic transcription-coupled
POLR2C (1,281 words) [view diff] exact match in snippet view article find links to article
nucleoplasm cytosol cytoplasm Biological process mRNA splicing, via spliceosome transcription elongation from RNA polymerase II promoter 7-methylguanosine
NOVA1 (673 words) [view diff] exact match in snippet view article find links to article
membrane-bounded organelle nucleus Biological process mRNA splicing, via spliceosome RNA processing locomotory behavior RNA splicing regulation of RNA metabolic
RBFOX1 (949 words) [view diff] exact match in snippet view article find links to article
splicing mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing nervous system development RNA transport Sources:Amigo /
WDR33 (562 words) [view diff] exact match in snippet view article find links to article
mRNA cleavage postreplication repair spermatogenesis mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA export from nucleus
DDX21 (890 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
SFPQ (1,226 words) [view diff] exact match in snippet view article find links to article
PMID 2480877. Gozani O, Patton JG, Reed R (Jul 1994). "A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably
RBM9 (909 words) [view diff] exact match in snippet view article find links to article
morphogenesis mRNA processing regulation of alternative mRNA splicing, via spliceosome nervous system development regulation of RNA splicing regulation of cell
MyoD (3,404 words) [view diff] exact match in snippet view article find links to article
muscle organ development regulation of alternative mRNA splicing, via spliceosome myotube cell development positive regulation of skeletal muscle fiber
SRPK1 (1,450 words) [view diff] exact match in snippet view article find links to article
chromosome segregation mRNA processing regulation of mRNA splicing, via spliceosome protein phosphorylation negative regulation of viral genome replication
CTNNBL1 (588 words) [view diff] exact match in snippet view article find links to article
process positive regulation of apoptotic process mRNA splicing, via spliceosome mRNA processing somatic diversification of immunoglobulins apoptotic
CHAF1B (1,338 words) [view diff] exact match in snippet view article find links to article
(Oct 2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo". Molecular and Cellular
ZTTK syndrome (2,932 words) [view diff] exact match in snippet view article find links to article
splice site and are dependent on SON to ensure efficient splicing and spliceosome recognition. The SON gene also plays a critical role during development
CPSF2 (904 words) [view diff] exact match in snippet view article find links to article
complex membrane nucleus nucleoplasm Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA polyadenylation mRNA
RNA binding protein, fox-1 homolog (c. elegans) 3 (138 words) [view diff] exact match in snippet view article
RNA splicing mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing nervous system development Sources:Amigo / QuickGO
WTAP (gene) (764 words) [view diff] exact match in snippet view article
processing mRNA methylation regulation of alternative mRNA splicing, via spliceosome multicellular organism development RNA metabolic process Sources:Amigo
MRNA surveillance (3,389 words) [view diff] exact match in snippet view article find links to article
This suggests involvement of the spliceosome in mammalian NMD. Research has investigated the possibility of spliceosome involvement in mammalian NMD and
POLR2I (956 words) [view diff] exact match in snippet view article find links to article
core complex nucleus nucleoplasm Biological process mRNA splicing, via spliceosome transcription elongation from RNA polymerase II promoter 7-methylguanosine
HNRPD (1,465 words) [view diff] exact match in snippet view article find links to article
development negative regulation of gene expression mRNA splicing, via spliceosome positive regulation of translation RNA processing liver development transcription
MTDH (1,482 words) [view diff] exact match in snippet view article find links to article
role in RISC and miRNA functions. MTDH has been shown to interact with spliceosome proteins in the cell nucleus and regulate the process of alternative
DDX1 (976 words) [view diff] exact match in snippet view article find links to article
translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this
NUDT21 (927 words) [view diff] exact match in snippet view article find links to article
polyadenylation specificity factor complex Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription protein tetramerization
TIA1 (1,263 words) [view diff] exact match in snippet view article find links to article
of epithelial cell apoptotic process regulation of mRNA splicing, via spliceosome protein localization to cytoplasmic stress granule apoptotic process
POLR2L (1,035 words) [view diff] exact match in snippet view article find links to article
process termination of RNA polymerase I transcription mRNA splicing, via spliceosome positive regulation of gene expression, epigenetic regulation of transcription
Zinc finger ccch-type containing 10 (80 words) [view diff] exact match in snippet view article find links to article
regulation of production of miRNAs involved in gene silencing by miRNA regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
CPSF3 (1,077 words) [view diff] exact match in snippet view article find links to article
factor complex nucleoplasm nucleus Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA 3'-end processing
Myelodysplastic syndrome (6,388 words) [view diff] exact match in snippet view article find links to article
PMID 15703420. Rozovski U, Keating M, Estrov Z (2012) The significance of spliceosome mutations in chronic lymphocytic leukemia. Leuk Lymphoma Molenaar RJ
JMJD6 (1,271 words) [view diff] exact match in snippet view article find links to article
mRNA processing sprouting angiogenesis regulation of mRNA splicing, via spliceosome transcription, DNA-templated histone H4-R3 demethylation multicellular
CSTF2 (1,112 words) [view diff] exact match in snippet view article find links to article
nucleoplasm nucleus nuclear body Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing mRNA 3'-end
KDM1A (1,706 words) [view diff] exact match in snippet view article find links to article
of transcription by RNA polymerase II alternative mRNA splicing, via spliceosome cerebral cortex development positive regulation of cell size response
POLR2G (1,119 words) [view diff] exact match in snippet view article find links to article
polymerase II, core complex nucleus Biological process mRNA splicing, via spliceosome positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
HTATSF1 (1,001 words) [view diff] exact match in snippet view article find links to article
transcription, elongation regulation of transcription, DNA-templated transcription, DNA-templated mRNA splicing, via spliceosome Sources:Amigo / QuickGO
POLR2K (1,059 words) [view diff] exact match in snippet view article find links to article
process termination of RNA polymerase I transcription mRNA splicing, via spliceosome positive regulation of gene expression, epigenetic regulation of transcription
YTHDC1 (1,247 words) [view diff] exact match in snippet view article find links to article
splice site selection RNA splicing regulation of mRNA splicing, via spliceosome mRNA export from nucleus dosage compensation by inactivation of X chromosome
CUGBP1 (2,269 words) [view diff] exact match in snippet view article find links to article
mRNA splice site selection regulation of alternative mRNA splicing, via spliceosome embryo development ending in birth or egg hatching Sources:Amigo / QuickGO
Far upstream element-binding protein 1 (1,047 words) [view diff] exact match in snippet view article find links to article
Lamond AI, Mann M (2002). "Large-scale proteomic analysis of the human spliceosome". Genome Res. 12 (8): 1231–45. doi:10.1101/gr.473902. PMC 186633. PMID 12176931
SYMPK (1,220 words) [view diff] exact match in snippet view article find links to article
positive regulation of protein dephosphorylation mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA export from nucleus
KHDRBS3 (1,258 words) [view diff] exact match in snippet view article find links to article
DNA-templated transcription, DNA-templated mRNA processing regulation of mRNA splicing, via spliceosome protein complex oligomerization Sources:Amigo / QuickGO
CSTF3 (812 words) [view diff] exact match in snippet view article find links to article
component nucleus nucleoplasm Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA polyadenylation mRNA
PRCC (gene) (742 words) [view diff] exact match in snippet view article
nucleoplasm nuclear speck Biological process cell cycle mitotic cell cycle checkpoint signaling mRNA splicing, via spliceosome Sources:Amigo / QuickGO
POLR2J (1,216 words) [view diff] exact match in snippet view article find links to article
RNA polymerase II, core complex Biological process mRNA splicing, via spliceosome transcription elongation from RNA polymerase II promoter 7-methylguanosine
CPSF1 (1,014 words) [view diff] exact match in snippet view article find links to article
factor complex nucleus nucleoplasm Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA polyadenylation mRNA
Tudor domain (1,565 words) [view diff] exact match in snippet view article find links to article
snRNPs. SMN promotes the maturation of snRNPs, which are essential for spliceosome assembly and intron removal. The proteins TP53BP1 (Tumor suppressor p53-binding
POLR2F (1,001 words) [view diff] exact match in snippet view article find links to article
process termination of RNA polymerase I transcription mRNA splicing, via spliceosome positive regulation of gene expression, epigenetic transcription initiation
POLR2E (1,178 words) [view diff] exact match in snippet view article find links to article
process termination of RNA polymerase I transcription mRNA splicing, via spliceosome positive regulation of gene expression, epigenetic transcription initiation
Trans-regulatory element (1,295 words) [view diff] exact match in snippet view article find links to article
snRNP control this mechanism by acting in trans. SR protein promotes the spliceosome assembly by interacting with snRNP(e.g. U1, U2) and splicing factors(e
PAPOLA (891 words) [view diff] exact match in snippet view article find links to article
cytoplasm nucleoplasm nucleus Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription RNA 3'-end processing
Tandem affinity purification (1,439 words) [view diff] exact match in snippet view article find links to article
snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome assembly". The EMBO Journal. 18 (12): 3463–3474. doi:10.1093/emboj/18
MBNL1 (1,056 words) [view diff] exact match in snippet view article find links to article
embryonic limb morphogenesis RNA splicing nervous system development regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
CPSF4 (820 words) [view diff] exact match in snippet view article find links to article
splicing, via endonucleolytic cleavage and ligation mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA polyadenylation mRNA
RNA-binding protein FUS (3,943 words) [view diff] exact match in snippet view article find links to article
Biological process cellular response to calcium ion mRNA splicing, via spliceosome regulation of transcription, DNA-templated regulation of transcription
UPF3B (1,173 words) [view diff] exact match in snippet view article find links to article
nucleolus nucleus cytoplasm cytosol Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA transport mRNA export
RNA polymerase II subunit B4 (1,013 words) [view diff] exact match in snippet view article find links to article
complex RNA polymerase complex Biological process mRNA splicing, via spliceosome recruitment of 3'-end processing factors to RNA polymerase II holoenzyme
Cugbp elav-like family member 6 (191 words) [view diff] exact match in snippet view article find links to article
complex Biological process mRNA processing regulation of alternative mRNA splicing, via spliceosome mRNA splice site selection Sources:Amigo / QuickGO
PUF60 (1,029 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated transcription, DNA-templated RNA splicing apoptotic process mRNA splicing, via spliceosome Sources:Amigo / QuickGO
FMR1 (3,456 words) [view diff] exact match in snippet view article find links to article
regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of neuronal action potential positive regulation of mRNA binding
PCBP1 (1,143 words) [view diff] exact match in snippet view article find links to article
cytoplasmic ribonucleoprotein granule Biological process mRNA splicing, via spliceosome viral RNA genome replication positive regulation of transcription by
HNRPH2 (766 words) [view diff] exact match in snippet view article find links to article
GO:0097481 postsynaptic density ribonucleoprotein complex Biological process mRNA splicing, via spliceosome RNA metabolic process Sources:Amigo / QuickGO
Protein arginine methyltransferase 5 (2,032 words) [view diff] exact match in snippet view article find links to article
Cook JR, Lee JH, Gunderson SI, Pestka S, Zieve GW, Clarke S (2004). "Spliceosome Sm proteins D1, D3, and B/B' are asymmetrically dimethylated at arginine
C1QBP (1,624 words) [view diff] exact match in snippet view article find links to article
spreading mature ribosome assembly negative regulation of mRNA splicing, via spliceosome immune response RNA splicing positive regulation of neutrophil chemotaxis
CHD8 (1,462 words) [view diff] exact match in snippet view article find links to article
(October 2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo". Molecular and Cellular
CUGBP2 (1,073 words) [view diff] exact match in snippet view article find links to article
processing regulation of heart contraction mRNA splice site selection regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
HNRPUL1 (1,029 words) [view diff] exact match in snippet view article find links to article
component nucleus nucleoplasm Biological process mRNA splicing, via spliceosome response to virus RNA processing regulation of transcription, DNA-templated
HNRPH3 (909 words) [view diff] exact match in snippet view article find links to article
spliceosomal complex nucleus nucleoplasm Biological process mRNA splicing, via spliceosome mRNA processing RNA processing epithelial cell differentiation RNA splicing
Non-POU domain-containing octamer-binding protein (2,492 words) [view diff] exact match in snippet view article find links to article
regulator complex nucleolus nucleus Biological process mRNA splicing, via spliceosome DNA recombination regulation of transcription, DNA-templated rhythmic
Splicing factor proline and glutamine rich (473 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated alternative mRNA splicing, via spliceosome DNA repair positive regulation of transcription by RNA polymerase II
RBM10 (5,524 words) [view diff] exact match in snippet view article find links to article
process mRNA processing regulation of alternative mRNA splicing, via spliceosome RNA splicing negative regulation of transcription by RNA polymerase II
THOC5 (1,473 words) [view diff] exact match in snippet view article find links to article
Gonzalez Sanchez MB, Tamura T, Sternberg D, Whetton AD (May 2008). "THOC5 spliceosome protein: a target for leukaemogenic tyrosine kinases that affects inositol
Gene structure (2,309 words) [view diff] exact match in snippet view article find links to article
Matera, A. Gregory; Wang, Zefeng (2014). "A day in the life of the spliceosome". Nature Reviews Molecular Cell Biology. 15 (2): 108–21. doi:10.1038/nrm3742
CCDC94 (935 words) [view diff] exact match in snippet view article find links to article
binding metal ion binding Cellular component U2-type catalytic step 1 spliceosome nucleus spliceosomal complex Biological process negative regulation of
Basic leucine zipper and W2 domain-containing protein 2 (1,597 words) [view diff] exact match in snippet view article find links to article
regulatory proteins that help in the functionality of BZW2. SNW1, a spliceosome protein, splices BZW2 mRNA variants. The protein rep is apart of SARS-CoV-2
ZGRF1 (1,687 words) [view diff] exact match in snippet view article find links to article
PMID 18164611. Schwer B (Jun 2008). "A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release". Molecular Cell. 30
GPATCH11 (1,152 words) [view diff] exact match in snippet view article find links to article
splicing factor, and may play a role in network interactions during spliceosome assembly. U2 small nuclear RNA auxiliary factor 1 U2AF1 Nucleus Plays
FIP1L1 (3,192 words) [view diff] exact match in snippet view article find links to article
polyadenylation specificity factor complex Biological process mRNA splicing, via spliceosome termination of RNA polymerase II transcription mRNA processing mRNA 3'-end
The Cancer Genome Atlas (4,551 words) [view diff] exact match in snippet view article find links to article
including transcription factor fusions, histone modifier mutations, spliceosome mutations and others Cutaneous Melanoma 331 X Established four subtypes:
Transcriptional amplification (1,718 words) [view diff] exact match in snippet view article find links to article
Webb, TR; Neel, BG; Shaw, CA; Westbrook, TF (17 September 2015). "The spliceosome is a therapeutic vulnerability in MYC-driven cancer". Nature. 525 (7569):
Small integral membrane protein 14 (1,830 words) [view diff] exact match in snippet view article find links to article
Stark, Holger (August 2017). "Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation". Cell. 170 (4): 701–713.e11. doi:10.1016/j.cell
FAM98A (2,452 words) [view diff] exact match in snippet view article find links to article
predicted to do. DDX1 is a putative ATP-dependent RNA helicase in a spliceosome, likely releasing the RNA from the splicing complex. C14orf166 is a polymerase