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Longer titles found: Sphingosine-1-phosphate (view), Sphingosine-1-phosphate receptor (view), Sphingosine-1-phosphate receptor modulator (view), Sphingosine N-acyltransferase (view), Sphingosine beta-galactosyltransferase (view), Sphingosine cholinephosphotransferase (view), Sphingosine kinase (view), Sphingosine kinase 1 (view), N,N-Dimethylsphingosine (view), 2-Hydroxyacylsphingosine 1-beta-galactosyltransferase (view)

searching for Sphingosine 42 found (658 total)

alternate case: sphingosine

SGPL1 (488 words) [view diff] exact match in snippet view article find links to article

Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1 gene. GRCh38: Ensembl release 89: ENSG00000166224 - Ensembl, May 2017
ASAH2 (687 words) [view diff] exact match in snippet view article find links to article
PMID 15946935. Tani M, Sano T, Ito M, Igarashi Y (2006). "Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets". J. Lipid Res. 46
SGPP1 (445 words) [view diff] exact match in snippet view article find links to article
Sphingosine-1-phosphate phosphatase 1 is an enzyme that in humans is encoded by the SGPP1 gene. ENSG00000285281 GRCh38: Ensembl release 89: ENSG00000126821
Long-chain-aldehyde dehydrogenase (605 words) [view diff] exact match in snippet view article find links to article
a co-factor. The encoded enzyme is responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid
A-971432 (362 words) [view diff] exact match in snippet view article find links to article
A-971432 is an orally bioavailable selective agonist of sphingosine-1-phosphate receptor 5 (S1PR5) discovered at AbbVie. It was discovered using high-throughput
HEK 293 cells (2,273 words) [view diff] exact match in snippet view article find links to article
(March 2001). "Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors". European Journal
Autotaxin (1,930 words) [view diff] exact match in snippet view article find links to article
"Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate". Journal of Lipid Research. 56 (6): 1134–44. doi:10.1194/jlr
Sphingomyelin deacylase (265 words) [view diff] exact match in snippet view article find links to article
H2O ⇌ {\displaystyle \rightleftharpoons } a fatty acid + D-glucosyl-sphingosine The enzyme is involved in the sphingolipid metabolism in the epidermis
Endoglycosylceramidase (149 words) [view diff] exact match in snippet view article find links to article
common use include endoglycoceramidase, EGCase, and glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase. As of late 2007, 6 structures have been
RPS6KC1 (425 words) [view diff] exact match in snippet view article find links to article
et al. (2002). "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein". J. Biol. Chem. 277 (36): 33319–24. doi:10
SPTLC2 (992 words) [view diff] exact match in snippet view article find links to article
Biological process • lipid metabolism • sphinganine biosynthetic process • sphingosine biosynthetic process • sphingolipid biosynthetic process • biosynthetic
Tameka A. Clemons (1,163 words) [view diff] exact match in snippet view article find links to article
She hypothesized that membrane associated sphingosine kinase (SK) signalling, leading to downstream sphingosine 1-phosphate release in the endoplasmic reticulum)
Didier Stainier (1,518 words) [view diff] exact match in snippet view article find links to article
several signaling pathways including sphingosine 1-phosphate signaling and the discovery of the long-elusive sphingosine 1-phosphate transporter. Additional
Flagellin (924 words) [view diff] exact match in snippet view article find links to article
(1): 2–11. PMID 9000497. Sharma N, Akhade AS, Qadri A (April 2013). "Sphingosine-1-phosphate suppresses TLR-induced CXCL8 secretion from human T cells"
Ceramide synthase 4 (486 words) [view diff] exact match in snippet view article find links to article
synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate". Journal of Biological Chemistry. 283 (9): 5677–5684. doi:10
Leukodystrophy (3,959 words) [view diff] exact match in snippet view article find links to article
These sphingolipids have been identified as galactosyl sphingosine and glycosyl sphingosine and are not present in unaffected individuals. Canavan disease
Chromosome 14 (1,728 words) [view diff] exact match in snippet view article find links to article
antitrypsin), member 1 SIX6OS1: encoding protein SIX6OS1 SGPP1: encoding enzyme Sphingosine-1-phosphate phosphatase 1 TC2N: encoding protein Tandem C2 domains nuclear
Kinetic exclusion assay (1,914 words) [view diff] exact match in snippet view article find links to article
Turksen, Kursad (eds.), "Measuring Sphingosine-1-Phosphate/Protein Interactions with the Kinetic Exclusion Assay", Sphingosine-1-Phosphate, New York, NY: Springer
GNA13 (2,070 words) [view diff] exact match in snippet view article find links to article
An S, Barr AJ, Manning DR (Sep 1999). "Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q)
Chromosome 10 (1,831 words) [view diff] exact match in snippet view article find links to article
ribosomal RNA processing 12 homolog RSU1: ras suppressor protein 1 SGPL1: sphingosine-1-phosphate lyase 1 SMNDC1: survival motor neuron domain containing 1
G protein-coupled inwardly-rectifying potassium channel (803 words) [view diff] exact match in snippet view article find links to article
serotonin, somatostatin, galanin, m-Glu, GABAB, TAAR1, CB1 and CB2, and sphingosine-1-phosphate receptors. Examples of GIRKs include a subset of potassium
Necroptosis (1,568 words) [view diff] exact match in snippet view article find links to article
enzymes into the cytoplasm by induction of reactive oxygen species by JNK, sphingosine production, and calpain activation by calcium release. Necroptosis has
Bone resorption (1,894 words) [view diff] exact match in snippet view article find links to article
Kawamura S, Okiji F, Shirazaki M, Sakai S, Saito H, Ishii M (Apr 2013). "Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical
Cholesteryl ester transfer protein (1,724 words) [view diff] exact match in snippet view article find links to article
Retrieved 18 October 2017. Okajima F (March 2002). "[Distribution of sphingosine 1-phosphate in plasma lipoproteins and its role in the regulation of
Glycosphingolipid deacylase (122 words) [view diff] exact match in snippet view article find links to article
ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids". Journal of Biochemistry. 103 (1): 1–4. PMID 3360750
EEA1 (514 words) [view diff] exact match in snippet view article find links to article
phagosome maturation in human macrophages via specific inhibition of sphingosine kinase". Journal of Immunology. 170 (6): 2811–5. doi:10.4049/jimmunol
ABL2 (1,448 words) [view diff] exact match in snippet view article find links to article
1204524. PMID 11494128. Endo A, Nagashima K, Kurose H, et al. (2002). "Sphingosine 1-phosphate induces membrane ruffling and increases motility of human
KLF2 (2,206 words) [view diff] exact match in snippet view article find links to article
for thymus emigration and differentiation into mature T-cells, such as sphingosine-1 phosphate receptor 1. KLF2 is a negative regulator of adipocyte differentiation
Epileptogenesis (2,047 words) [view diff] exact match in snippet view article find links to article
inhibition of interleukin 1β signaling by drugs such as VX-765; modulation of sphingosine 1-phosphate signaling by drugs such as fingolimod; activation of the
CERS6 (gene) (120 words) [view diff] exact match in snippet view article
Gene ontology Molecular function • DNA binding • sphingosine N-acyltransferase activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription
Epileptogenesis (2,047 words) [view diff] exact match in snippet view article find links to article
inhibition of interleukin 1β signaling by drugs such as VX-765; modulation of sphingosine 1-phosphate signaling by drugs such as fingolimod; activation of the
CERS6 (gene) (120 words) [view diff] exact match in snippet view article
Gene ontology Molecular function • DNA binding • sphingosine N-acyltransferase activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription
ROCK1 (2,257 words) [view diff] exact match in snippet view article find links to article
1.5-2-fold. Without RhoA binding, lipids such as arachidonic acid or sphingosine phosphorylcholine can increase ROCK1 activity 5- to 6-fold. These two
DEGS2 (266 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • oxidoreductase activity • sphingosine hydroxylase activity • sphingolipid delta-4 desaturase activity Cellular component
PPAP2B (2,112 words) [view diff] exact match in snippet view article find links to article
Garcia JG (December 1999). "Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function
Eukaryotic translation elongation factor 1 alpha 1 (2,664 words) [view diff] exact match in snippet view article find links to article
• protein biosynthesis • protein methylation • neutrophil degranulation • regulation of D-erythro-sphingosine kinase activity Sources:Amigo / QuickGO
Phosphatidic acid phosphatase 2c (494 words) [view diff] exact match in snippet view article find links to article
protein binding • lipid phosphatase activity • hydrolase activity • sphingosine-1-phosphate phosphatase activity • phosphatidate phosphatase activity
Hexadecanol dehydrogenase (155 words) [view diff] exact match in snippet view article find links to article
1021/bi00807a007. PMID 4313936. Stoffel W, LeKim D, Heyn G (1970). "Metabolism of sphingosine bases. XIV. Sphinganine (dihydrosphingosine), an effective donor of the
PDXK (796 words) [view diff] exact match in snippet view article find links to article
Smith E, Surowiec SM, et al. (1993). "Synthesis of N-(4'-pyridoxyl)sphingosine and its uptake and metabolism by isolated cells". Membrane Biochemistry
FAM57B (415 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function • sphingosine N-acyltransferase activity Cellular component • integral component of membrane • Golgi membrane • Golgi
Ceramide synthase 5 (643 words) [view diff] exact match in snippet view article find links to article
activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1". Mol Cancer Res. 5 (8): 801–12. doi:10.1158/1541-7786.MCR-07-0100
Solute carrier family (3,333 words) [view diff] exact match in snippet view article find links to article
transporter family (MFSD5(SLC61A1)) Pyrophosphate transporters (ANKH(SLC62A1)) Sphingosine-phosphate transporters (SPNS1(SLC63A1), SPNS2(SLC63A2), SPNS3(SLC63A3))