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Longer titles found: Sphingolipidoses (view), Ormdl sphingolipid biosynthesis regulator 1 (view), Ormdl sphingolipid biosynthesis regulator 3 (view), 1-Deoxysphingolipids (view)

searching for Sphingolipid 94 found (185 total)

alternate case: sphingolipid

Palmitoyl-CoA (633 words) [view diff] exact match in snippet view article find links to article

Palmitoyl-CoA is also the starting substrate, along with Serine, for sphingolipid biosynthesis. Palmitoyl CoA and Serine participate in a condensation
Prosaposin (1,789 words) [view diff] exact match in snippet view article find links to article
cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each domain of the precursor protein is approximately
Delta8-fatty-acid desaturase (271 words) [view diff] exact match in snippet view article find links to article
Delta8-fatty-acid desaturase (EC 1.14.19.4, Delta8-sphingolipid desaturase, EFD1, BoDES8, SLD, Delta8 fatty acid desaturase, Delta8-desaturase) is an enzyme
StAR-related transfer domain (765 words) [view diff] no match in snippet view article find links to article
START (StAR-related lipid-transfer) is a lipid-binding domain in StAR, HD-ZIP and signalling proteins. The archetypical domain is found in StAR (Steroidogenic
SGPL1 (488 words) [view diff] exact match in snippet view article find links to article
signaling pathway face morphogenesis apoptotic process sphingolipid metabolic process sphingolipid catabolic process hemopoiesis ameboidal-type cell migration
SPNS2 (589 words) [view diff] exact match in snippet view article find links to article
T, Hisano Y, Fukui H, Yamaguchi A, Mochizuki N (January 2009). "The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors"
SMPD3 (593 words) [view diff] exact match in snippet view article find links to article
"Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism". J. Biol. Chem. 278 (16): 13775–83. doi:10.1074/jbc.M212262200
Naunyn-Schmiedeberg's Archives of Pharmacology (246 words) [view diff] exact match in snippet view article find links to article
Experimental and Clinical Pharmacology and Toxicology (DGPT), and of the Sphingolipid Club. The journal is published by Springer on a monthly basis and is
GBA2 (937 words) [view diff] exact match in snippet view article find links to article
catabolic process central nervous system neuron development metabolism sphingolipid metabolic process central nervous system development cholesterol metabolic
SMPD2 (525 words) [view diff] exact match in snippet view article find links to article
(March 1998). "Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?". Proceedings of the National Academy of Sciences of the United
Acyloxyacyl hydrolase (390 words) [view diff] exact match in snippet view article find links to article
granulysin, acid sphingomyelinase, surfactant protein B, and the 4 sphingolipid activator proteins (saposins). The larger subunit, Mr = 50,000, contains
SGPP1 (445 words) [view diff] exact match in snippet view article find links to article
process sphingolipid biosynthetic process extrinsic apoptotic signaling pathway dephosphorylation sphinganine-1-phosphate metabolic process sphingolipid metabolic
ABCC1 (1,849 words) [view diff] exact match in snippet view article find links to article
activity GO:0004012 ATPase-coupled intramembrane lipid transporter activity sphingolipid floppase activity GO:0022891 transmembrane transporter activity Cellular
Pleurotolysin (1,157 words) [view diff] exact match in snippet view article find links to article
tools to detect and visualize ceramide phosphoethanolamine, a major sphingolipid in invertebrates but not in animals. It may be distantly related to members
PRKD2 (932 words) [view diff] exact match in snippet view article find links to article
transcription by RNA polymerase II positive regulation of cell adhesion sphingolipid biosynthetic process peptidyl-serine phosphorylation peptidyl-threonine
S1PR2 (1,111 words) [view diff] exact match in snippet view article find links to article
Dodd D, Gygax D, Korte M, Schwab ME, Schiavo G (14 January 2014). "The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity"
ARV1 (347 words) [view diff] exact match in snippet view article find links to article
(September 2002). "Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1". The Journal of Biological
KCNV2 (578 words) [view diff] exact match in snippet view article find links to article
et al. (2007). "Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol". Channels
Plant-specific insert (1,439 words) [view diff] exact match in snippet view article find links to article
surfactant-associated protein B (pulmonary surfactant regulation) and the saposins (sphingolipid degradation) of which SAPLIPs are named after. Specific to the PSI, it
KLF14 (564 words) [view diff] exact match in snippet view article find links to article
regulation of transcription by RNA polymerase II positive regulation of sphingolipid mediated signaling pathway regulation of transcription by RNA polymerase
SGMS1 (859 words) [view diff] exact match in snippet view article find links to article
sphingomyelin biosynthetic process sphingolipid biosynthetic process phosphorylation apoptotic process sphingolipid metabolic process ceramide biosynthetic
Long-chain-aldehyde dehydrogenase (605 words) [view diff] exact match in snippet view article find links to article
development sesquiterpenoid metabolic process phytol metabolic process sphingolipid biosynthetic process cellular aldehyde metabolic process central nervous
ASAH2 (687 words) [view diff] exact match in snippet view article find links to article
mitochondrion extracellular region Biological process lipid metabolism sphingolipid metabolic process apoptotic process sphingosine metabolic process ceramide
Ceramide synthase 3 (606 words) [view diff] exact match in snippet view article find links to article
FM, Gröne HJ, Sandhoff R (2008). "Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide
ALDH3B2 (458 words) [view diff] exact match in snippet view article find links to article
Biological process ethanol catabolic process metabolism alcohol metabolic process lipid metabolism sphingolipid biosynthetic process Sources:Amigo / QuickGO
Sphingosine kinase 1 (1,099 words) [view diff] exact match in snippet view article find links to article
sphingosine biosynthetic process positive regulation of mitotic cell cycle sphingolipid biosynthetic process positive regulation of angiogenesis positive regulation
Jessie Stevenson Kovalenko Medal (87 words) [view diff] exact match in snippet view article find links to article
infection. Roscoe O. Brady 1991 For revolutionary accomplishments in human sphingolipid storage disorders, including the discovery of enzymatic defects, the
Chromosome 14 (1,728 words) [view diff] exact match in snippet view article find links to article
ATP-dependent RNA helicase DDX24 DEGS2: encoding protein Delta(4)-desaturase, sphingolipid 2 DLGAP5: Disks large-associated protein 5 DGLUCY: encoding protein DGLUCY
Protein kinase D1 (1,305 words) [view diff] exact match in snippet view article find links to article
regulation of endothelial cell chemotaxis protein kinase D signaling sphingolipid biosynthetic process negative regulation of cell death nervous system
Biochemical systems theory (545 words) [view diff] exact match in snippet view article find links to article
2003. F. Alvarez-Vasquez et al., Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae, Nature 27, pp. 433(7024), pp
PSAPL1 (84 words) [view diff] exact match in snippet view article find links to article
epithelial cell differentiation involved in prostate gland development sphingolipid metabolic process lipid metabolism GO:0048554 positive regulation of
PRKD3 (1,070 words) [view diff] exact match in snippet view article find links to article
pathway GO:0007243 intracellular signal transduction phosphorylation sphingolipid biosynthetic process protein kinase D signaling Sources:Amigo / QuickGO
CD69 (2,262 words) [view diff] exact match in snippet view article find links to article
membrane that bind to the ligand sphingosine-1-phosphate (S1P). S1P is a sphingolipid metabolite that is abundant in the bloodstream and, upon binding to S1P1
Psychosine (82 words) [view diff] exact match in snippet view article find links to article
; Demchenko, A. V.; Sands, M. S. (2013). "Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture"
ALDH3B1 (833 words) [view diff] exact match in snippet view article find links to article
ethanol catabolic process lipid metabolism aldehyde catabolic process sphingolipid biosynthetic process cellular aldehyde metabolic process cellular response
CERS6 (gene) (120 words) [view diff] exact match in snippet view article
membrane nucleus endoplasmic reticulum Biological process lipid metabolism sphingolipid biosynthetic process ceramide biosynthetic process regulation of transcription
SERINC1 (406 words) [view diff] exact match in snippet view article find links to article
activity positive regulation of serine C-palmitoyltransferase activity sphingolipid metabolic process phospholipid biosynthetic process lipid metabolism
Collagen, type XXIII, alpha 1 (1,550 words) [view diff] exact match in snippet view article find links to article
XXIII are usually found in lipid rafts, which are cholesterol-rich and sphingolipid-rich, tightly-packed microdomains of the cell membrane. Furin proteases
PPAP2B (2,112 words) [view diff] exact match in snippet view article find links to article
participates in interactions within the triacylglyceride synthesis and sphingolipid metabolism pathways. GRCh38: Ensembl release 89: ENSG00000162407 - Ensembl
H. E. Carter (656 words) [view diff] exact match in snippet view article find links to article
Carter, H. E., R. C. Gaver, and R. K. Yu. 1966. A novel branched-chain sphingolipid base from Crithidia facsiculata. Biochem. Biophys. Res. Commun. 22: 316–320
PHB2 (857 words) [view diff] exact match in snippet view article find links to article
C-terminus binding GO:0001948 protein binding estrogen receptor binding sphingolipid binding Cellular component cytoplasm membrane nuclear matrix cell surface
S1PR1 (2,038 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function sphingolipid binding sphingosine-1-phosphate receptor activity G protein-coupled receptor activity signal transducer activity
Phosphatidic acid phosphatase 2c (494 words) [view diff] exact match in snippet view article find links to article
membrane membrane Biological process phospholipid metabolic process sphingolipid biosynthetic process phospholipid dephosphorylation signal transduction
PTPLAD1 (577 words) [view diff] exact match in snippet view article find links to article
GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity sphingolipid biosynthetic process Sources:Amigo / QuickGO
Ceramide synthase 5 (643 words) [view diff] exact match in snippet view article find links to article
"LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia". J Lipid Res. 46 (6): 1229–38. doi:10.1194/jlr
PPT1 (1,112 words) [view diff] exact match in snippet view article find links to article
brain development membrane raft organization protein catabolic process sphingolipid catabolic process negative regulation of cell growth protein transport
GAL3ST1 (652 words) [view diff] exact match in snippet view article find links to article
galactosylceramide biosynthetic process protein N-linked glycosylation spermatogenesis sphingolipid metabolic process lipid metabolism Sources:Amigo / QuickGO
Major facilitator superfamily domain containing 2b (174 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function sphingolipid transporter activity symporter activity transporter activity Cellular component membrane integral component
ELOVL5 (492 words) [view diff] exact match in snippet view article find links to article
positive regulation of fatty acid biosynthetic process fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process Sources:Amigo / QuickGO
SERINC3 (697 words) [view diff] exact match in snippet view article find links to article
endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway sphingolipid metabolic process L-serine transport immune system process L-serine biosynthetic
ELOVL4 (869 words) [view diff] exact match in snippet view article find links to article
long-chain fatty acid biosynthetic process detection of visible light sphingolipid biosynthetic process fatty acid elongation, monounsaturated fatty acid
Thomas J. Pucadyil (1,061 words) [view diff] exact match in snippet view article find links to article
Amitabha (1 April 2017). "Sphingolipids modulate the function of human serotonin1A receptors: Insights from sphingolipid-deficient cells". Biochimica
3-hydroxyacyl-CoA dehydratase 2 (226 words) [view diff] exact match in snippet view article find links to article
Biological process fatty acid elongation fatty acid biosynthetic process sphingolipid biosynthetic process long-chain fatty-acyl-CoA biosynthetic process very
Northern epilepsy syndrome (1,065 words) [view diff] exact match in snippet view article find links to article
accumulation of subunit c of mitochondrial ATP synthase and a small amount of sphingolipid activator proteins in the neurons. β-amyloid, a peptide involved in Alzheimer's
West Nile virus (4,916 words) [view diff] exact match in snippet view article find links to article
"The Composition of West Nile Virus Lipid Envelope Unveils a Role of Sphingolipid Metabolism in Flavivirus Biogenesis". Journal of Virology. 88 (20): 12041–12054
Thermotoga maritima (1,633 words) [view diff] exact match in snippet view article find links to article
Nikolova-Karakashian, Mariana; Vales, Teresa R.; Vance, Dennis E. (1995-06-09). "Sphingolipid Biosynthesisde Novoby Rat Hepatocytes in Culture". Journal of Biological
TECR (454 words) [view diff] exact match in snippet view article find links to article
process very long-chain fatty acid biosynthetic process fatty acid metabolic process lipid metabolism sphingolipid metabolic process Sources:Amigo / QuickGO
Lipotoxicity (1,380 words) [view diff] exact match in snippet view article find links to article
of lipotoxicity to the perturbation of membrane glycerophospholipid/sphingolipid homeostasis and their associated signalling events. Currently, there
Sarah Spiegel (829 words) [view diff] exact match in snippet view article find links to article
2016 Winter Symposium. 2015. Retrieved 2 September 2015. "Glycolipid & Sphingolipid Biology". Gordon Research Conferences. 2015. Retrieved 2 September 2015
List of MeSH codes (D08) (15,232 words) [view diff] no match in snippet view article
The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)
B4GALT5 (769 words) [view diff] exact match in snippet view article find links to article
protein stability positive regulation of embryonic development neuron maturation lipid metabolism sphingolipid metabolic process Sources:Amigo / QuickGO
PPAP2A (861 words) [view diff] exact match in snippet view article find links to article
signaling pathway intracellular steroid hormone receptor signaling pathway sphingolipid biosynthetic process germ cell migration negative regulation of cell
2-Hydroxyacylsphingosine 1-beta-galactosyltransferase (218 words) [view diff] exact match in snippet view article find links to article
Shayman, James (2006). "Glucosylceramide and Galactosylceramide Synthase". Sphingolipid Biology. Tokyon: Springer. pp. 83–94. doi:10.1007/4-431-34200-1_6.
VAPB (1,284 words) [view diff] exact match in snippet view article find links to article
host cell COPII-coated vesicle budding cellular calcium ion homeostasis sphingolipid biosynthetic process endoplasmic reticulum organization positive regulation
Ceramide synthase 2 (826 words) [view diff] exact match in snippet view article find links to article
myelination, suggesting that it is important for the synthesis of myelin sphingolipids. The lack of CerS2, as shown in knockout mice, induces the autophagy
ST8SIA1 (1,027 words) [view diff] exact match in snippet view article find links to article
response to heat positive regulation of cell population proliferation sphingolipid metabolic process lipid metabolism carbohydrate metabolic process Sources:Amigo
SERINC5 (529 words) [view diff] exact match in snippet view article find links to article
CDP-diacylglycerol-serine O-phosphatidyltransferase activity defense response to virus sphingolipid metabolic process L-serine biosynthetic process Sources:Amigo / QuickGO
List of EC numbers (EC 1) (35,916 words) [view diff] exact match in snippet view article
13Z-forming) EC 1.14.19.17: sphingolipid 4-desaturase EC 1.14.19.18: sphingolipid 8-(E)-desaturase EC 1.14.19.19: sphingolipid 10-desaturase EC 1.14.19.20:
Surfactant protein B (2,164 words) [view diff] exact match in snippet view article find links to article
metabolic process respiratory gaseous exchange by respiratory system sphingolipid metabolic process lipid metabolism GO:0048554 positive regulation of
LRP1 (3,563 words) [view diff] exact match in snippet view article find links to article
Protein C inhibitor, Pseudomonas exotoxin A, RAP, Ricin A, SHC1, and Sphingolipid activator protein, SYNJ2BP. Tat, Thrombin, THBS1, Thrombospondin 2, TIMP1
NGFRAP1 (835 words) [view diff] exact match in snippet view article find links to article
regulates crosstalk between Trk A tyrosine kinase and p75(NTR)-dependent sphingolipid signaling pathways". J. Neurochem. 76 (5): 1540–51. doi:10.1046/j.1471-4159
Very-long-chain 3-oxoacyl-CoA synthase (495 words) [view diff] exact match in snippet view article find links to article
cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation". The Journal of Biological Chemistry. 272 (28): 17376–84.
Coccolithovirus (1,703 words) [view diff] exact match in snippet view article find links to article
proteases as well as at least four genes that encode proteins involved in sphingolipid biosynthesis. These were shown to have been acquired from the host via
Michael Fischbach (962 words) [view diff] exact match in snippet view article find links to article
the gut commensal Bacteroides fragilis produces the immune modulatory sphingolipid alpha-galactosylceramide, showed that the production of neurotransmitters
GeneMatcher (2,008 words) [view diff] case mismatch in snippet view article find links to article
Retrieved 2019-12-29. "OMIM Entry - * 615843 - DELTA(4)-DESATURASE, SPHINGOLIPID, 1; DEGS1". omim.org. Retrieved 2019-12-29. Pant, Devesh C.; Dorboz,
Tyrosine hydroxylase (4,394 words) [view diff] exact match in snippet view article find links to article
social behavior cellular response to manganese ion response to ether sphingolipid metabolic process response to immobilization stress norepinephrine biosynthetic
GeneMatcher (2,008 words) [view diff] case mismatch in snippet view article find links to article
Retrieved 2019-12-29. "OMIM Entry - * 615843 - DELTA(4)-DESATURASE, SPHINGOLIPID, 1; DEGS1". omim.org. Retrieved 2019-12-29. Pant, Devesh C.; Dorboz,
Tyrosine hydroxylase (4,394 words) [view diff] exact match in snippet view article find links to article
social behavior cellular response to manganese ion response to ether sphingolipid metabolic process response to immobilization stress norepinephrine biosynthetic
SPHK2 (629 words) [view diff] exact match in snippet view article find links to article
sphingosine biosynthetic process negative regulation of apoptotic process sphingolipid biosynthetic process brain development blood vessel development positive
NPC1 (1,947 words) [view diff] exact match in snippet view article find links to article
JF, et al. (June 2001). "Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of
TRAF2 (3,714 words) [view diff] exact match in snippet view article find links to article
Gene ontology Molecular function sphingolipid binding lipid binding CD40 receptor binding mitogen-activated protein kinase kinase kinase binding zinc ion
IGFBP3 (4,673 words) [view diff] exact match in snippet view article find links to article
IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways". FASEB J. 18 (12): 1456–8. doi:10.1096/fj.04-1618fje
Stacey Missmer (575 words) [view diff] exact match in snippet view article find links to article
Riley; Katherine A Hendricks; et al. (1 April 2004). "Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture
VAPA (1,884 words) [view diff] exact match in snippet view article find links to article
cell death membrane fusion protein folding in endoplasmic reticulum sphingolipid biosynthetic process endoplasmic reticulum organization positive regulation
Gunnar Blix (442 words) [view diff] exact match in snippet view article find links to article
old cemetery. Julian N. Kanfer; Sen-itiroh Hakomori (6 December 2012). Sphingolipid Biochemistry. Springer Science & Business Media. pp. 148–. ISBN 978-1-4757-0396-2
Hereditary sensory and autonomic neuropathy (3,402 words) [view diff] exact match in snippet view article find links to article
(SPT). The SPT enzyme is involved in making certain fats called sphingolipids. Sphingolipids are important components of cell membranes and play a role in
Reticulon 4 (1,908 words) [view diff] exact match in snippet view article find links to article
positive regulation of toll-like receptor 9 signaling pathway protein localization to lysosome cellular sphingolipid homeostasis Sources:Amigo / QuickGO
Eberhard Voit (1,113 words) [view diff] exact match in snippet view article find links to article
E. O. Voit, and Y. A. Hannun. Simulation and evaluation of de novo sphingolipid fluxes in S. cerevisiae. ‘’Nature ‘’ ‘’’433(7024) ‘’’, 425-430 (2005)
ALOXE3 (2,576 words) [view diff] exact match in snippet view article find links to article
perception of pain arachidonic acid metabolic process fat cell differentiation sphingolipid metabolic process lipoxygenase pathway Sources:Amigo / QuickGO
ENPP7 (2,869 words) [view diff] exact match in snippet view article find links to article
significant amounts of alkaline sphingomyelinase, neutral ceramidase, and sphingolipid metabolites". Pediatr. Res. 61 (1): 61–6. doi:10.1203/01.pdr.0000250534
List of EC numbers (EC 2) (21,735 words) [view diff] exact match in snippet view article
methyltransferase EC 2.1.1.316: mitomycin 6-O-methyltransferase EC 2.1.1.317: sphingolipid C9-methyltransferase EC 2.1.1.318: [trehalose-6-phosphate synthase]-L-cysteine
Sortilin 1 (3,268 words) [view diff] exact match in snippet view article find links to article
Canuel M, Morales CR (December 2003). "The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin". The EMBO Journal
Hugo J. Bellen (2,871 words) [view diff] exact match in snippet view article find links to article
Matthew N; Bellen, Hugo J (2016). "Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals". eLife. 5. doi:10.7554/eLife.20732. ISSN 2050-084X
Hemagglutinin esterase (3,610 words) [view diff] exact match in snippet view article find links to article
influenza A and B virus are associated with membrane rafts, cholesterol- and sphingolipid-enriched nanodomains of the plasma membrane, HEF is thought to localize