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Longer titles found: Sphingolipidoses (view), Ormdl sphingolipid biosynthesis regulator 3 (view), 1-Deoxysphingolipids (view)

searching for Sphingolipid 100 found (194 total)

alternate case: sphingolipid

Palmitoyl-CoA (612 words) [view diff] exact match in snippet view article find links to article

Palmitoyl-CoA is also the starting substrate, along with serine, for sphingolipid biosynthesis. Palmitoyl CoA and serine participate in a condensation

Prosaposin (1,791 words) [view diff] exact match in snippet view article find links to article

cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each domain of the precursor protein is approximately

SPTLC2 (1,162 words) [view diff] exact match in snippet view article find links to article

chain base subunit 2". Nagiec MM, Lester RL, Dickson RC (October 1996). "Sphingolipid synthesis: identification and characterization of mammalian cDNAs encoding

Delta8-fatty-acid desaturase (275 words) [view diff] exact match in snippet view article find links to article

Delta8-fatty-acid desaturase (EC 1.14.19.4, Delta8-sphingolipid desaturase, EFD1, BoDES8, SLD, Delta8 fatty acid desaturase, Delta8-desaturase) is an enzyme

ORMDL1 (209 words) [view diff] exact match in snippet view article find links to article

ORMDL sphingolipid biosynthesis regulator 1 is a protein that in humans is encoded by the ORMDL1 gene. GRCh38: Ensembl release 89: ENSG00000128699 – Ensembl

SPNS2 (197 words) [view diff] exact match in snippet view article find links to article

T, Hisano Y, Fukui H, Yamaguchi A, Mochizuki N (January 2009). "The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors"

StAR-related transfer domain (776 words) [view diff] no match in snippet view article find links to article

START (StAR-related lipid-transfer) is a lipid-binding domain in StAR, HD-ZIP and signalling proteins. The archetypical domain is found in StAR (Steroidogenic

Naunyn-Schmiedeberg's Archives of Pharmacology (246 words) [view diff] exact match in snippet view article find links to article

Experimental and Clinical Pharmacology and Toxicology (DGPT), and of the Sphingolipid Club. The journal is published by Springer on a monthly basis and is

Acyloxyacyl hydrolase (348 words) [view diff] exact match in snippet view article find links to article

granulysin, acid sphingomyelinase, surfactant protein B, and the 4 sphingolipid activator proteins (saposins). The larger subunit, of 50 kDa, contains

SGPL1 (491 words) [view diff] exact match in snippet view article find links to article

signaling pathway face morphogenesis apoptotic process sphingolipid metabolic process sphingolipid catabolic process hemopoiesis ameboidal-type cell migration

SMPD3 (595 words) [view diff] exact match in snippet view article find links to article

"Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism". J. Biol. Chem. 278 (16): 13775–83. doi:10.1074/jbc.M212262200

SMPD2 (525 words) [view diff] exact match in snippet view article find links to article

(March 1998). "Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?". Proceedings of the National Academy of Sciences of the United

SGPP1 (448 words) [view diff] exact match in snippet view article find links to article

process sphingolipid biosynthetic process extrinsic apoptotic signaling pathway dephosphorylation sphinganine-1-phosphate metabolic process sphingolipid metabolic

Pleurotolysin (1,167 words) [view diff] exact match in snippet view article find links to article

tools to detect and visualize ceramide phosphoethanolamine, a major sphingolipid in invertebrates but not in animals. It may be distantly related to members

SGMS1 (559 words) [view diff] exact match in snippet view article find links to article

sphingomyelin biosynthetic process sphingolipid biosynthetic process phosphorylation apoptotic process sphingolipid metabolic process ceramide biosynthetic

GBA2 (942 words) [view diff] exact match in snippet view article find links to article

catabolic process central nervous system neuron development metabolism sphingolipid metabolic process central nervous system development cholesterol metabolic

KCNV2 (582 words) [view diff] exact match in snippet view article find links to article

et al. (2007). "Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol". Channels

ABCC1 (1,849 words) [view diff] exact match in snippet view article find links to article

transporter activity ATPase-coupled intramembrane lipid transporter activity sphingolipid floppase activity transmembrane transporter activity Cellular component

Sphingosine kinase 1 (1,115 words) [view diff] exact match in snippet view article find links to article

sphingosine biosynthetic process positive regulation of mitotic cell cycle sphingolipid biosynthetic process positive regulation of angiogenesis positive regulation

ARV1 (347 words) [view diff] exact match in snippet view article find links to article

(September 2002). "Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1". The Journal of Biological

Long-chain-aldehyde dehydrogenase (613 words) [view diff] exact match in snippet view article find links to article

development sesquiterpenoid metabolic process phytol metabolic process sphingolipid biosynthetic process cellular aldehyde metabolic process central nervous

Plant-specific insert (1,455 words) [view diff] exact match in snippet view article find links to article

surfactant-associated protein B (pulmonary surfactant regulation) and the saposins (sphingolipid degradation) of which SAPLIPs are named after. Specific to the PSI, it

KLF14 (567 words) [view diff] exact match in snippet view article find links to article

regulation of transcription by RNA polymerase II positive regulation of sphingolipid mediated signaling pathway regulation of transcription by RNA polymerase

ASAH2 (687 words) [view diff] exact match in snippet view article find links to article

mitochondrion extracellular region Biological process lipid metabolism sphingolipid metabolic process apoptotic process sphingosine metabolic process ceramide

S1PR2 (1,154 words) [view diff] exact match in snippet view article find links to article

Dodd D, Gygax D, Korte M, Schwab ME, Schiavo G (14 January 2014). "The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity"

Biochemical systems theory (545 words) [view diff] exact match in snippet view article find links to article

2003. F. Alvarez-Vasquez et al., Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae, Nature 27, pp. 433(7024), pp

PRKD2 (940 words) [view diff] exact match in snippet view article find links to article

transcription by RNA polymerase II positive regulation of cell adhesion sphingolipid biosynthetic process peptidyl-serine phosphorylation peptidyl-threonine

Protein kinase D1 (1,304 words) [view diff] exact match in snippet view article find links to article

regulation of endothelial cell chemotaxis protein kinase D signaling sphingolipid biosynthetic process negative regulation of cell death nervous system

Cell wall protein 2 (1,667 words) [view diff] exact match in snippet view article find links to article

cell's response to acidity. In the instances where yeast cells lack sphingolipids, they struggle to thrive in low pH environments. Specific strains such

Jessie Stevenson Kovalenko Medal (87 words) [view diff] exact match in snippet view article find links to article

infection. Roscoe O. Brady 1991 For revolutionary accomplishments in human sphingolipid storage disorders, including the discovery of enzymatic defects, the

Ceramide synthase 3 (612 words) [view diff] exact match in snippet view article find links to article

FM, Gröne HJ, Sandhoff R (2008). "Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide

ALDH3B2 (493 words) [view diff] exact match in snippet view article find links to article

Biological process ethanol catabolic process metabolism alcohol metabolic process lipid metabolism sphingolipid biosynthetic process Sources:Amigo / QuickGO

PRKD3 (1,073 words) [view diff] exact match in snippet view article find links to article

signaling pathway intracellular signal transduction phosphorylation sphingolipid biosynthetic process protein kinase D signaling Sources:Amigo / QuickGO

ALDH3B1 (520 words) [view diff] exact match in snippet view article find links to article

ethanol catabolic process lipid metabolism aldehyde catabolic process sphingolipid biosynthetic process cellular aldehyde metabolic process cellular response

Psychosine (82 words) [view diff] exact match in snippet view article find links to article

; Demchenko, A. V.; Sands, M. S. (2013). "Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture"

Chromosome 14 (1,831 words) [view diff] exact match in snippet view article find links to article

ATP-dependent RNA helicase DDX24 DEGS2: encoding protein Delta(4)-desaturase, sphingolipid 2 DLGAP5: Disks large-associated protein 5 DGLUCY: encoding protein DGLUCY

SERINC1 (412 words) [view diff] exact match in snippet view article find links to article

activity positive regulation of serine C-palmitoyltransferase activity sphingolipid metabolic process phospholipid biosynthetic process lipid metabolism

PPAP2B (2,069 words) [view diff] exact match in snippet view article find links to article

participates in interactions within the triacylglyceride synthesis and sphingolipid metabolism pathways. GRCh38: Ensembl release 89: ENSG00000162407 – Ensembl

CD69 (2,275 words) [view diff] exact match in snippet view article find links to article

membrane that bind to the ligand sphingosine-1-phosphate (S1P). S1P is a sphingolipid metabolite that is abundant in the bloodstream and, upon binding to S1PR1

CERS6 (120 words) [view diff] exact match in snippet view article find links to article

membrane nucleus endoplasmic reticulum Biological process lipid metabolism sphingolipid biosynthetic process ceramide biosynthetic process regulation of transcription

PSAPL1 (84 words) [view diff] exact match in snippet view article find links to article

epithelial cell differentiation involved in prostate gland development sphingolipid metabolic process lipid metabolism positive regulation of catalytic activity

Ceramide synthase 5 (643 words) [view diff] exact match in snippet view article find links to article

"LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia". J Lipid Res. 46 (6): 1229–38. doi:10.1194/jlr

SERINC3 (486 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway sphingolipid metabolic process L-serine transport immune system process L-serine biosynthetic

GAL3ST1 (657 words) [view diff] exact match in snippet view article find links to article

galactosylceramide biosynthetic process protein N-linked glycosylation spermatogenesis sphingolipid metabolic process lipid metabolism Sources:Amigo / QuickGO

Ceramide synthase 5 (643 words) [view diff] exact match in snippet view article find links to article

"LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia". J Lipid Res. 46 (6): 1229–38. doi:10.1194/jlr

List of EC numbers (EC 1) (24,607 words) [view diff] exact match in snippet view article

13Z-forming) EC 1.14.19.17: sphingolipid 4-desaturase EC 1.14.19.18: sphingolipid 8-(E)-desaturase EC 1.14.19.19: sphingolipid 10-desaturase EC 1.14.19.20:

Collagen, type XXIII, alpha 1 (1,559 words) [view diff] exact match in snippet view article find links to article

XXIII are usually found in lipid rafts, which are cholesterol-rich and sphingolipid-rich, tightly-packed microdomains of the cell membrane. Furin proteases

PHB2 (863 words) [view diff] exact match in snippet view article find links to article

protein C-terminus binding protein binding estrogen receptor binding sphingolipid binding Cellular component cytoplasm membrane nuclear matrix cell surface

PPT1 (1,114 words) [view diff] exact match in snippet view article find links to article

brain development membrane raft organization protein catabolic process sphingolipid catabolic process negative regulation of cell growth protein transport

Thomas J. Pucadyil (1,054 words) [view diff] exact match in snippet view article find links to article

Amitabha (1 April 2017). "Sphingolipids modulate the function of human serotonin1A receptors: Insights from sphingolipid-deficient cells". Biochimica

Major facilitator superfamily domain containing 2b (174 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function sphingolipid transporter activity symporter activity transporter activity Cellular component membrane integral component

S1PR1 (2,449 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function sphingolipid binding sphingosine-1-phosphate receptor activity G protein-coupled receptor activity signal transducer activity

PTPLAD1 (580 words) [view diff] exact match in snippet view article find links to article

signal transduction I-kappaB kinase/NF-kappaB signaling positive regulation of GTPase activity sphingolipid biosynthetic process Sources:Amigo / QuickGO

ELOVL5 (495 words) [view diff] exact match in snippet view article find links to article

positive regulation of fatty acid biosynthetic process fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process Sources:Amigo / QuickGO

Sortilin 1 (3,170 words) [view diff] exact match in snippet view article find links to article

Santulli G (February 2022). "Sortilin drives hypertension by modulating sphingolipid/ceramide homeostasis and by triggering oxidative stress". The Journal

List of MeSH codes (D08) (15,232 words) [view diff] no match in snippet view article

The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

3-hydroxyacyl-CoA dehydratase 2 (226 words) [view diff] exact match in snippet view article find links to article

Biological process fatty acid elongation fatty acid biosynthetic process sphingolipid biosynthetic process long-chain fatty-acyl-CoA biosynthetic process very

Sarah Spiegel (biologist) (838 words) [view diff] exact match in snippet view article

2016 Winter Symposium. 2015. Retrieved 2 September 2015. "Glycolipid & Sphingolipid Biology". Gordon Research Conferences. 2015. Retrieved 2 September 2015

VAPB (1,298 words) [view diff] exact match in snippet view article find links to article

process COPII-coated vesicle budding cellular calcium ion homeostasis sphingolipid biosynthetic process endoplasmic reticulum organization positive regulation

Lipotoxicity (1,458 words) [view diff] exact match in snippet view article find links to article

of lipotoxicity to the perturbation of membrane glycerophospholipid/sphingolipid homeostasis and their associated signalling events. Currently, there

Northern epilepsy syndrome (1,065 words) [view diff] exact match in snippet view article find links to article

accumulation of subunit c of mitochondrial ATP synthase and a small amount of sphingolipid activator proteins in the neurons. β-amyloid, a peptide involved in Alzheimer's

Very-long-chain 3-oxoacyl-CoA synthase (498 words) [view diff] exact match in snippet view article find links to article

cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation". The Journal of Biological Chemistry. 272 (28): 17376–84.

TECR (454 words) [view diff] exact match in snippet view article find links to article

process very long-chain fatty acid biosynthetic process fatty acid metabolic process lipid metabolism sphingolipid metabolic process Sources:Amigo / QuickGO

B4GALT5 (778 words) [view diff] exact match in snippet view article find links to article

protein stability positive regulation of embryonic development neuron maturation lipid metabolism sphingolipid metabolic process Sources:Amigo / QuickGO

West Nile virus (4,959 words) [view diff] exact match in snippet view article find links to article

"The Composition of West Nile Virus Lipid Envelope Unveils a Role of Sphingolipid Metabolism in Flavivirus Biogenesis". Journal of Virology. 88 (20): 12041–12054

Surfactant protein B (2,179 words) [view diff] exact match in snippet view article find links to article

organ morphogenesis respiratory gaseous exchange by respiratory system sphingolipid metabolic process lipid metabolism positive regulation of catalytic activity

2-Hydroxyacylsphingosine 1-beta-galactosyltransferase (219 words) [view diff] exact match in snippet view article find links to article

Shayman, James (2006). "Glucosylceramide and Galactosylceramide Synthase". Sphingolipid Biology. Tokyon: Springer. pp. 83–94. doi:10.1007/4-431-34200-1_6.

PPAP2A (886 words) [view diff] exact match in snippet view article find links to article

signaling pathway intracellular steroid hormone receptor signaling pathway sphingolipid biosynthetic process germ cell migration negative regulation of cell

Acetyl-CoA carboxylase (2,990 words) [view diff] exact match in snippet view article find links to article

functional genomics reveals a role for the lysine acetyltransferase NuA4 and sphingolipid metabolism in regulating Acc1 activity and localization". Genetics. 221

Michael Fischbach (965 words) [view diff] exact match in snippet view article find links to article

the gut commensal Bacteroides fragilis produces the immune modulatory sphingolipid alpha-galactosylceramide, showed that the production of neurotransmitters

LRP1 (3,450 words) [view diff] exact match in snippet view article find links to article

Protein C inhibitor, Pseudomonas exotoxin A, RAP, Ricin A, SHC1, and Sphingolipid activator protein, SYNJ2BP. Tat, Thrombin, THBS1, Thrombospondin 2, TIMP1

Ceramide synthase 2 (840 words) [view diff] exact match in snippet view article find links to article

myelination, suggesting that it is important for the synthesis of myelin sphingolipids. The lack of CerS2, as shown in knockout mice, induces the autophagy

ST8SIA1 (1,036 words) [view diff] exact match in snippet view article find links to article

response to heat positive regulation of cell population proliferation sphingolipid metabolic process lipid metabolism carbohydrate metabolic process Sources:Amigo

Coccolithovirus (1,717 words) [view diff] exact match in snippet view article find links to article

proteases as well as at least four genes that encode proteins involved in sphingolipid biosynthesis. These were shown to have been acquired from the host via

Gunnar Blix (445 words) [view diff] exact match in snippet view article find links to article

old cemetery. Julian N. Kanfer; Sen-itiroh Hakomori (6 December 2012). Sphingolipid Biochemistry. Springer Science & Business Media. pp. 148–. ISBN 978-1-4757-0396-2

NGFRAP1 (847 words) [view diff] exact match in snippet view article find links to article

regulates crosstalk between Trk A tyrosine kinase and p75(NTR)-dependent sphingolipid signaling pathways". J. Neurochem. 76 (5): 1540–51. doi:10.1046/j.1471-4159

Eastern blot (2,101 words) [view diff] exact match in snippet view article find links to article

Polyvinylidene Difluoride Membrane (Far-Eastern Blotting) and Its Applications". Sphingolipid Metabolism and Cell Signaling, Part B. Methods in Enzymology. Vol. 312

Thermotoga maritima (1,971 words) [view diff] exact match in snippet view article find links to article

S, Wang E, Nikolova-Karakashian M, Vales TR, Vance DE (June 1995). "Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin

Tyrosine hydroxylase (4,405 words) [view diff] exact match in snippet view article find links to article

social behavior cellular response to manganese ion response to ether sphingolipid metabolic process response to immobilization stress norepinephrine biosynthetic

GeneMatcher (2,008 words) [view diff] case mismatch in snippet view article find links to article

Retrieved 2019-12-29. "OMIM Entry - * 615843 - DELTA(4)-DESATURASE, SPHINGOLIPID, 1; DEGS1". omim.org. Retrieved 2019-12-29. Pant, Devesh C.; Dorboz,

SERINC5 (529 words) [view diff] exact match in snippet view article find links to article

CDP-diacylglycerol-serine O-phosphatidyltransferase activity defense response to virus sphingolipid metabolic process L-serine biosynthetic process Sources:Amigo / QuickGO

ALOX12B (1,704 words) [view diff] exact match in snippet view article find links to article

expression protein lipidation positive regulation of mucus secretion sphingolipid metabolic process positive regulation of MAPK cascade arachidonic acid

Survival activating factor enhancement (1,087 words) [view diff] exact match in snippet view article find links to article

role and reduces infarct damage. TNF-α production also activates the sphingolipid pathway, protein kinase C and the mitochondrial potassium ATP dependent

VAPA (1,892 words) [view diff] exact match in snippet view article find links to article

cell death membrane fusion protein folding in endoplasmic reticulum sphingolipid biosynthetic process endoplasmic reticulum organization positive regulation

IGFBP3 (4,717 words) [view diff] exact match in snippet view article find links to article

IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways". FASEB Journal. 18 (12): 1456–1458. doi:10.1096/fj

TRAF2 (3,427 words) [view diff] exact match in snippet view article find links to article

Gene ontology Molecular function sphingolipid binding lipid binding CD40 receptor binding mitogen-activated protein kinase kinase kinase binding zinc ion

SPHK2 (715 words) [view diff] exact match in snippet view article find links to article

sphingosine biosynthetic process negative regulation of apoptotic process sphingolipid biosynthetic process brain development blood vessel development positive

Stacey Missmer (584 words) [view diff] exact match in snippet view article find links to article

Riley; Katherine A Hendricks; et al. (April 1, 2004). "Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture

NPC1 (2,718 words) [view diff] exact match in snippet view article find links to article

WD, et al. (June 2001). "Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of

Reticulon 4 (1,924 words) [view diff] exact match in snippet view article find links to article

positive regulation of toll-like receptor 9 signaling pathway protein localization to lysosome cellular sphingolipid homeostasis Sources:Amigo / QuickGO

Hereditary sensory and autonomic neuropathy (3,691 words) [view diff] exact match in snippet view article find links to article

(SPT). The SPT enzyme is involved in making certain fats called sphingolipids. Sphingolipids are important components of cell membranes and play a role in

ELOVL4 (2,114 words) [view diff] exact match in snippet view article find links to article

long-chain fatty acid biosynthetic process detection of visible light sphingolipid biosynthetic process fatty acid elongation, monounsaturated fatty acid

ALOXE3 (2,593 words) [view diff] exact match in snippet view article find links to article

perception of pain arachidonic acid metabolic process fat cell differentiation sphingolipid metabolic process lipoxygenase pathway Sources:Amigo / QuickGO

Eberhard Voit (1,259 words) [view diff] exact match in snippet view article find links to article

E. O. Voit, and Y. A. Hannun. Simulation and evaluation of de novo sphingolipid fluxes in S. cerevisiae. Nature 433(7024), 425-430 (2005). Voit, E.O

Jürgen Seibel (806 words) [view diff] exact match in snippet view article find links to article

Trushnal Waghmare, Jan Schlegel, Jürgen Seibel and Burkhard Kleuser. Sphingolipids: Effectors and Achilles Heals in Viral Infections?, Cells 2021, 10(9)

ENPP7 (2,882 words) [view diff] exact match in snippet view article find links to article

significant amounts of alkaline sphingomyelinase, neutral ceramidase, and sphingolipid metabolites". Pediatr. Res. 61 (1): 61–6. doi:10.1203/01.pdr.0000250534

List of EC numbers (EC 2) (21,664 words) [view diff] exact match in snippet view article

methyltransferase EC 2.1.1.316: mitomycin 6-O-methyltransferase EC 2.1.1.317: sphingolipid C9-methyltransferase EC 2.1.1.318: [trehalose-6-phosphate synthase]-L-cysteine

Hugo J. Bellen (2,899 words) [view diff] exact match in snippet view article find links to article

Matthew N; Bellen, Hugo J (2016). "Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals". eLife. 5. doi:10.7554/eLife.20732. ISSN 2050-084X

Hemagglutinin esterase (3,623 words) [view diff] exact match in snippet view article find links to article

influenza A and B virus are associated with membrane rafts, cholesterol- and sphingolipid-enriched nanodomains of the plasma membrane, HEF is thought to localize

Spongy degeneration of the central nervous system (3,567 words) [view diff] exact match in snippet view article find links to article

Central Nervous System (Van Bogaert–Bertrand Type)". Inborn Disorders of Sphingolipid Metabolism. Elsevier. pp. 129–147. doi:10.1016/b978-1-4831-9855-2.50013-7