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searching for Skin biopsy 109 found (201 total)

Pitted keratolysis (1,149 words) [view diff] exact match in snippet view article find links to article

shoes/boots are worn for extended periods of time without removing/cleaning. Skin biopsy specimens are not usually utilized, as the diagnosis of pitted keratolysis

Small fiber neuropathy (2,238 words) [view diff] exact match in snippet view article find links to article

diagnosis of small fiber neuropathy and follow-up of treatment efficacy. A skin biopsy for the measurement of epidermal nerve fiber density is an increasingly

Nevus anemicus (514 words) [view diff] exact match in snippet view article find links to article

represent a sustained localized adrenergic vasoconstriction. Results of a skin biopsy would be interpreted as normal and only physiological testing can reveal

Blueberry muffin baby (1,508 words) [view diff] exact match in snippet view article find links to article

count, TORCH infections, haemoglobin, viral cultures and Coombs test. A skin biopsy may be useful. Conditions that may appear similar include hemangiopericytoma

Staphylococcal scalded skin syndrome (852 words) [view diff] exact match in snippet view article find links to article

of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer

Dermatopathology (790 words) [view diff] exact match in snippet view article find links to article

those criteria do not allow a conclusive diagnosis to be made, and a skin biopsy is taken to be examined under the microscope or are subject to other

Jarlath Udoudo Umoh (693 words) [view diff] exact match in snippet view article find links to article

on the dissemination of rabies virus in tissues, developed the use of skin biopsy for in vitro diagnosis of rabies in 1983. Umoh hails from Ikot Ekpene

Diploid-triploid mosaicism (359 words) [view diff] exact match in snippet view article find links to article

severe. The chromosome disorder is usually not present in the blood; a skin biopsy, or analyzing cells in the urine is needed to detect the triploid cells

Tuberculoid leprosy (171 words) [view diff] exact match in snippet view article find links to article

Tuberculoid leprosy Skin biopsy in tuberculoid leprosy showing multiple peri-appendageal granulomas. Specialty Infectious diseases

Porphyria cutanea tarda (3,499 words) [view diff] exact match in snippet view article find links to article

fluorescence with Wood's lamp, testing a 24-hour urine for porphyrins, and skin biopsy. Pseudoporphyria may appear similar. PCT may be distinguished from epidermolysis

Acne mechanica (1,548 words) [view diff] exact match in snippet view article find links to article

a dermatologist via a physical examination. In more extreme cases, a skin biopsy is performed to examine the pathology. Family and medical history are

Calciphylaxis (2,870 words) [view diff] exact match in snippet view article find links to article

and found in multiples. The suspected diagnosis can be supported by a skin biopsy, usually a punch biopsy, which shows arterial calcification and occlusion

Perioral dermatitis (4,514 words) [view diff] exact match in snippet view article find links to article

report irritation but are usually asymptomatic. For children with GPD, a skin biopsy showing granulomatous infiltrate is needed to confirm diagnosis in an

Adrenergic urticaria (316 words) [view diff] exact match in snippet view article find links to article

propranolol, which suppresses the rash and prevents further exacerbations. Skin biopsy specimens of adrenergic urticaria show edematous tissues with a vague

Pityriasis lichenoides chronica (285 words) [view diff] exact match in snippet view article find links to article

infection can be suspected. Diagnostic method Clinical and morphological evaluation can be difficult. Skin biopsy from a scaly papule can be diagnostic.

Cutaneous small-vessel vasculitis (1,506 words) [view diff] exact match in snippet view article find links to article

exclusion and requires ruling out systemic causes of the skin findings. Skin biopsy (punch or excisional) is the most definitive diagnostic test and should

Neutrophilic eccrine hidradenitis (960 words) [view diff] exact match in snippet view article find links to article

toxic effect on the eccrine glands. In all cases of suspected NEH, a skin biopsy should be performed, because the clinical symptoms are non specific,

Sneddon's syndrome (561 words) [view diff] exact match in snippet view article find links to article

Sneddon's patients will have abnormal results, although brain MRI and skin biopsy are often abnormal. The diagnosis is based on a detailed history and

Neuropathology (1,211 words) [view diff] exact match in snippet view article find links to article

(ENFD) is a more recently developed neuropathology test in which a punch skin biopsy is taken to identify small fiber neuropathies by analyzing the nerve

Eccrine carcinoma (701 words) [view diff] exact match in snippet view article find links to article

carcinomas. There is no research yet as to what causes Eccrine carcinoma. A skin biopsy is the most common test used to diagnose eccrine carcinoma. The biopsy

Tuberculosis verrucosa cutis (476 words) [view diff] exact match in snippet view article find links to article

chromoblastomycosis.[citation needed] The diagnosis is confirmed by a skin biopsy and a positive culture for acid-fast bacilli. A PPD test may also result

Pemphigus (2,005 words) [view diff] exact match in snippet view article find links to article

mucous membrane biopsy by a dermatopathologist or oral pathologist. The skin biopsy is taken from the edge of a blister, prepared for histopathology and

Urticarial vasculitis (710 words) [view diff] exact match in snippet view article find links to article

with the identification of at least two conditions from: venulitis on skin biopsy, arthritis, ocular inflammation, abdominal pain or positive C1q antibodies

Aquarium granuloma (1,120 words) [view diff] exact match in snippet view article find links to article

combination of antibiotics is based on the results of the culture and skin biopsy. The treatment can take up to several months. Surgery may also be needed

Acrodermatitis chronica atrophicans (421 words) [view diff] exact match in snippet view article find links to article

methods include microscopy and culture (in modified Kelly's medium) of skin biopsy or blood samples. Antibiotics is recommended in treatment of ACA. Doxycycline

Nocardiosis (1,253 words) [view diff] exact match in snippet view article find links to article

to: a chest x-ray to analyze the lungs, a bronchoscopy, a brain/lung/skin biopsy, or a sputum culture. However, diagnosis may be difficult. Nocardiae

Chronic mucocutaneous candidiasis (735 words) [view diff] exact match in snippet view article find links to article

methods/tests: Thyroid function test Liver function test Cellular immunity test Skin biopsy Genetic testing Management for an individual with chronic mucocutaneous

Corner stitch (224 words) [view diff] exact match in snippet view article find links to article

adjacent to the initial entry point.[citation needed] Zuber, TJ (1998), "Skin biopsy, excision, and repair techniques", Soft tissue surgery for the family

Ichthyosis prematurity syndrome (1,127 words) [view diff] exact match in snippet view article find links to article

electron microscopy is also conducted. A specimen of skin is obtained via a skin biopsy and analyzed to see any tell tale characteristics. Genetic testing can

Nevus depigmentosus (664 words) [view diff] exact match in snippet view article find links to article

made based on the presence of depigmented patches, and confirmed with a skin biopsy.[citation needed] Different therapeutic modalities have been attempted

Id reaction (885 words) [view diff] exact match in snippet view article find links to article

be considered if there is suspicion of allergic contact dermatitis. A skin biopsy is rarely necessary, but if done mostly shows an interstitial granulomatous

Actinic granuloma (731 words) [view diff] exact match in snippet view article find links to article

sun damage and possibly to injured elastic fibers. Diagnostic method Skin biopsy. Differential diagnosis Granuloma annulare and necrobiosis lipoidica

Prurigo nodularis (1,498 words) [view diff] exact match in snippet view article find links to article

examination and the presence of itching for greater than 6 weeks duration. A skin biopsy is often performed to exclude other diseases. Lesion biopsies usually

Erythema marginatum (863 words) [view diff] exact match in snippet view article find links to article

marginatum can be made during examination of the skin's appearance. A skin biopsy may be performed if needed to confirm the diagnosis. Medical history

Menkes disease (1,558 words) [view diff] exact match in snippet view article find links to article

be diagnosed by blood tests of the copper and ceruloplasmin levels, skin biopsy, and optical microscopic examination of the hair to view characteristic

Febrile neutrophilic dermatosis (1,204 words) [view diff] exact match in snippet view article find links to article

30 mm/h) (90%), and a slight increase in alkaline phosphatase (83%). Skin biopsy shows a papillary and mid-dermal mixed infiltrate of polymorphonuclear

Incontinentia pigmenti (1,079 words) [view diff] exact match in snippet view article find links to article

is established by clinical findings and occasionally by corroborative skin biopsy. Molecular genetic testing of the NEMO IKBKG gene (chromosomal locus

Tinea cruris (1,096 words) [view diff] exact match in snippet view article find links to article

culture of skin scrapings, a KOH examination to check for fungus, or skin biopsy. The symptoms of tinea cruris may be similar to other causes of itch

Erythema annulare centrifugum (775 words) [view diff] exact match in snippet view article find links to article

Hormone (Contraceptive Pill, Stress, Hormone Drugs) Lyme disease A skin biopsy can be performed to test for EAC; tests should be performed to rule out

Erythema ab igne (990 words) [view diff] exact match in snippet view article find links to article

persistent sore that does not heal or a growing lump within the rash, a skin biopsy should be performed to rule out the possibility of skin cancer. If the

Inborn errors of metabolism (1,526 words) [view diff] exact match in snippet view article find links to article

disorders):[citation needed] Tissue biopsy: liver, muscle, brain, bone marrow Skin biopsy and fibroblast cultivation for specific enzyme testing Specific DNA testing

Ichthyosis (1,008 words) [view diff] exact match in snippet view article find links to article

also useful in determining the mode of inheritance. In some cases, a skin biopsy is done to help to confirm the diagnosis while in others genetic testing

Eosinophilic fasciitis (1,344 words) [view diff] exact match in snippet view article find links to article

Raynaud phenomenon and exclusion of systemic sclerosis) histology of a skin biopsy shows fibrosis of the subcutaneous connective tissue, with thickening

Bullous pemphigoid (1,621 words) [view diff] exact match in snippet view article find links to article

serrated pattern) by direct immunofluorescence microscopy (DIF) on a skin biopsy specimen, and (3) positive epidermal side staining by indirect immunofluorescence

Zack Robidas (334 words) [view diff] exact match in snippet view article find links to article

misdiagnosed as mastitis in early 2020 and after three rounds of antibiotics, a skin biopsy revealed she had Stage IV, metastatic inflammatory breast cancer. Since

Port-wine stain (1,139 words) [view diff] exact match in snippet view article find links to article

based entirely upon the history and appearance. In unusual cases, a skin biopsy may be needed to confirm the diagnosis. Depending on the location of

Cholinergic urticaria (1,719 words) [view diff] exact match in snippet view article find links to article

testing can indicate anhidrosis and/or hypohidrosis (see Minor test). A skin biopsy may reveal cellular infiltrates in sweat glands or ducts. Severe heat

Pemphigoid (5,858 words) [view diff] exact match in snippet view article find links to article

pemphigoid. Diagnosis of bullous pemphigoid includes clinical assessment, skin biopsy for histopathology and direct immunofluorescence, indirect immunofluorescence

Acanthosis nigricans (1,761 words) [view diff] exact match in snippet view article find links to article

the body. Acanthosis nigricans is typically diagnosed clinically. A skin biopsy may be needed in unusual cases. If no clear cause is obvious, it may

Adult polyglucosan body disease (994 words) [view diff] exact match in snippet view article find links to article

of functional glycogen branching enzyme can be determined by taking a skin biopsy and testing for activity of the enzyme. Examination of tissue biopsied

Horizontal mattress stitch (365 words) [view diff] exact match in snippet view article find links to article

also has the benefit of helping with hemostasis. Zuber, TJ (1998). "Skin biopsy, excision, and repair techniques". Soft tissue surgery for the family

Degos disease (1,651 words) [view diff] exact match in snippet view article find links to article

ill was found to have C5b-9 complexes in the involved vessels of the skin biopsy. Eculizumab was then used for treatment of the thrombotic microangiopathy

CADASIL (1,908 words) [view diff] exact match in snippet view article find links to article

S2CID 13031278. Joutel A, Favrole P, Labauge P, et al. (December 2001). "Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis"

Schamberg disease (1,612 words) [view diff] exact match in snippet view article find links to article

tests are usually indicated. Additional testing may aid diagnosis. A skin biopsy may be taken to determine capillaritis of dermal vessels. Capillaritis

Feline viral rhinotracheitis (1,577 words) [view diff] exact match in snippet view article find links to article

; Maggs, David J. (2006). "Detection of feline herpesvirus 1 DNA in skin biopsy specimens from cats with or without dermatitis". Journal of the American

Anne Joutel (778 words) [view diff] exact match in snippet view article find links to article

Joutel, P Favrole, P Labauge, H Chabriat, C Lescoat, F Andreux. 2001. Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis

Pallister–Killian syndrome (1,950 words) [view diff] exact match in snippet view article find links to article

form an individual's cultured skin fibroblasts, i.e. fibroblasts from a skin biopsy grown in a laboratory for at least several days. The sSMC in these tissues

Surgical incision (2,010 words) [view diff] exact match in snippet view article find links to article

Kenneth E.; Lucroy, Michael D. (2004-11-15). "Histologic comparison of skin biopsy specimens collected by use of carbon dioxide or 810-nm diode lasers from

Panniculitis (1,167 words) [view diff] exact match in snippet view article find links to article

tissue (cutaneous or visceral) and is often diagnosed based on a deep skin biopsy, and can be further classified by histological characteristics based

Mastocytosis (2,716 words) [view diff] exact match in snippet view article find links to article

Other names Clonal bone marrow disorder Micrograph of mastocytosis. Skin biopsy. H&E stain. Specialty Clinical Immunology and Allergy, Oncology, hematology

Alport syndrome (2,534 words) [view diff] exact match in snippet view article find links to article

L, Kostaridou S, Skiathitou A, Georgaki E, Sotsiou F (April 2008). "Skin biopsy for the diagnosis of Alport syndrome". Hippokratia. 12 (2): 116–8. PMC 2464308

Metal toxicity (2,235 words) [view diff] exact match in snippet view article find links to article

pigmentary changes had used nose drops containing silver for many years. His skin biopsy showed silver deposits in the dermis, confirming the diagnosis of generalized

Ectodermal dysplasia (2,121 words) [view diff] exact match in snippet view article find links to article

when sweating turns the yellow starch-iodine powder to deep purple. Skin biopsy is another diagnostic method which allows for documentation of hypohidrosis

Azeezia Medical College (447 words) [view diff] case mismatch in snippet view article find links to article

Microdermabrasion PRP Intralesional Injections Botox and Fillers Diagnostic Tests Skin Biopsy Food Allergy Test Patch Test Azeezia Medical College is sanctioned with

June K. Robinson (1,944 words) [view diff] case mismatch in snippet view article find links to article

characteristics of elasticity and mobility in the text, Fundamentals of Skin Biopsy. She implemented the reconstruction theory of the facial cosmetic units

Breast biopsy (2,157 words) [view diff] no match in snippet view article find links to article

target the area with radiation if needed. Percutaneous ("through the skin") biopsy methods have become more favored over surgical biopsies due to the high

Hunter syndrome (2,599 words) [view diff] exact match in snippet view article find links to article

measuring I2S activity in serum, white blood cells, or fibroblasts from skin biopsy. In some people with MPS II, analysis of the I2S gene can determine clinical

Harlequin-type ichthyosis (3,103 words) [view diff] exact match in snippet view article find links to article

This test reveals a loss of function mutation on the ABCA12 gene. A skin biopsy may be done to assess the histologic characteristics of the cells. Histological

Psoriasis (12,962 words) [view diff] exact match in snippet view article find links to article

diagnosis is typically made based on history and clinical exam findings. Skin biopsy can also be performed which typically shows a psoriasiform reaction pattern

Paraneoplastic pemphigus (2,528 words) [view diff] exact match in snippet view article find links to article

several tests may be performed. Initially, samples are obtained via skin biopsy for routine microscopy and direct immunofluorescence (DIF) testing. The

Pseudoxanthoma elasticum (3,409 words) [view diff] exact match in snippet view article find links to article

peripheral tissues. The diagnostic criteria for PXE are the typical skin biopsy appearance and the presence of angioid streaks in the retina. Criteria

Bartonellosis (3,073 words) [view diff] exact match in snippet view article find links to article

(angiomatous tumours). The bacterium can be seen microscopically if a skin biopsy is silver stained (the Warthin–Starry method).[citation needed] Cat-scratch

Oculocutaneous albinism type I (1,604 words) [view diff] exact match in snippet view article find links to article

major types of OCA. Prenatal testing has been achieved through fetal skin biopsy followed by subsequent histologic and electron microscope examination

Guo-li Ming (755 words) [view diff] exact match in snippet view article find links to article

conducted by Russell L. Margolis and Christopher A. Ross. She used various skin biopsy samples of family members affected with schizophrenia to develop a technique

Alopecia X (547 words) [view diff] exact match in snippet view article find links to article

cyclic flank alopecia, follicular dysplasia, and sebaceous adentitis. A skin biopsy will typically show the same changes as other endocrinopathies. There

Walter Freudenthal (1,304 words) [view diff] case mismatch in snippet view article find links to article

Chest, 1 January 1948, doi:10.1016/S0366-0869(48)80003-1, pp. 11–16. "Skin Biopsy", in Sidney Campbell (Ed.) Dyke's Recent Advances in Clinical Pathology

Henoch–Schönlein purpura (3,422 words) [view diff] exact match in snippet view article find links to article

findings: diffuse abdominal pain, predominant IgA deposition (confirmed on skin biopsy), acute arthritis in any joint, and renal involvement (as evidenced by

Allergic contact dermatitis (2,697 words) [view diff] exact match in snippet view article find links to article

dermatitis and rule out other potential causes of the symptoms include a skin biopsy and culture of the skin lesion. The clinical expression of the dermatitis

Inflammatory breast cancer (2,651 words) [view diff] exact match in snippet view article find links to article

characterised by the presence of cancer cells in the subdermal lymphatics on skin biopsy. Consequently, IBC is always staged at stage IIIB or above, as that type

Sweat gland (4,625 words) [view diff] exact match in snippet view article find links to article

Cabello, A.; Garcia Merino, A. (November 1992). "Diagnosis by axilla skin biopsy in an early case of Lafora's disease". Journal of Neurology, Neurosurgery

Urbach–Wiethe disease (2,518 words) [view diff] exact match in snippet view article find links to article

disease Other names Lipoid proteinosis and Hyalinosis cutis et mucosae Urbach–Wiethe disease in skin biopsy with H&E stain. Specialty Endocrinology

Eccrine angiomatous hamartoma (1,400 words) [view diff] exact match in snippet view article find links to article

rise to an abnormal proliferation of adnexal and vascular structures. A skin biopsy is typically performed for definitive diagnosis. The histopathologic

Mycosis fungoides (4,001 words) [view diff] exact match in snippet view article find links to article

difference. Histology The criteria for the disease are established on the skin biopsy by the presence of the following: Presence of cancer cells with twisted

Rocky Mountain spotted fever (4,360 words) [view diff] exact match in snippet view article find links to article

concentration, or elevated liver enzyme levels. Serology testing and skin biopsy are considered to be the best methods of diagnosis. Although immunofluorescent

Dementia with Lewy bodies (14,381 words) [view diff] exact match in snippet view article find links to article

structures, and measures of synucleinopathy in CSF. While commercial skin biopsy tests for DLB are available in the US, and the FDA has given a breakthrough

Hereditary fibrosing poikiloderma with tendon contractures, myopathy, and pulmonary fibrosis (425 words) [view diff] exact match in snippet view article find links to article

of the muscles. Muscle biopsy shows fibrosis and fatty infiltration. Skin biopsy shows fibrosis and alterations of the elastic network. This condition

Mitochondrial myopathy (3,617 words) [view diff] exact match in snippet view article find links to article

to disease expression only in skeletal muscle, with fibroblasts (from skin biopsy) appearing normal. Blood tests: lactate/pyruvate ratio may be elevated

Cladophialophora carrionii (1,775 words) [view diff] exact match in snippet view article find links to article

susceptibility to contracting chromoblastomycosis. Histology tests from a skin biopsy can identify muriform cells that are commonly found in chromoblastomycosis

Parvovirus B19 (4,063 words) [view diff] exact match in snippet view article find links to article

association with parvovirus B19 was described, after virus was demonstrated in skin biopsy samples, subsequently corroborated in numerous publications. Arthralgias

Primary ovarian insufficiency (4,792 words) [view diff] exact match in snippet view article find links to article

changes than others." 11. "...could a scientist create more <eggs> from a skin biopsy?... Surely, this kind of technology should exist somewhere." and 12.

Mycobacterium leprae (5,280 words) [view diff] exact match in snippet view article find links to article

"Efficacy of fluorescent microscopy versus modified Fite-Faraco stain in skin biopsy specimens of leprosy cases - a comparative study". International Journal

Levamisole-induced necrosis syndrome (1,757 words) [view diff] exact match in snippet view article find links to article

the cheek region, nose, and lips with complete sparing of the back. Skin biopsy revealed extensive small vessel thrombosis throughout the superficial

Glycogen storage disease type II (4,318 words) [view diff] exact match in snippet view article find links to article

is made by estimating the acid alpha-glucosidase activity in either skin biopsy (fibroblasts), muscle biopsy (muscle cells), or white blood cells. The

Niemann–Pick disease type C (4,604 words) [view diff] exact match in snippet view article find links to article

unesterified cholesterol with filipin. The fibroblasts are grown from a small skin biopsy taken from a patient with suspected NPC. The diagnosis can be confirmed

Melon-headed whale (4,747 words) [view diff] exact match in snippet view article find links to article

between the two species, particularly in head shape. Genetic testing of a skin biopsy sample confirmed that the individual was a hybrid between a female melon-headed

Ehlers–Danlos syndrome (12,474 words) [view diff] exact match in snippet view article find links to article

Diagnostic tests include collagen gene-variant testing, collagen typing via skin biopsy, echocardiogram, and lysyl hydroxylase or oxidase activity, but these

ISCU (1,761 words) [view diff] exact match in snippet view article find links to article

does not last. The disease is limited to muscle, with fibroblasts from skin biopsy being unaffected. As non-muscle tissues are unaffected, this necessitates

Overdiagnosis (3,545 words) [view diff] exact match in snippet view article find links to article

H Gilbert; Woloshin, Steven; Schwartz, Lisa M (3 September 2005). "Skin biopsy rates and incidence of melanoma: population based ecological study".

Infantile hemangioma (5,788 words) [view diff] exact match in snippet view article find links to article

vessels. Tissue for diagnosis can be obtained via fine-needle aspiration, skin biopsy, or excisional biopsy. Under the microscope, IHs are unencapsulated aggregates

List of infectious diseases (1,692 words) [view diff] exact match in snippet view article find links to article

Nocardiosis chest x-ray to analyze the lungs, a bronchoscopy, a brain/lung/skin biopsy, or a sputum culture. trimethoprim/sulfamethoxazole or high doses of

Epidermal growth factor receptor (6,893 words) [view diff] exact match in snippet view article find links to article

mutation was supported by in vitro experiments and functional analysis of a skin biopsy. His severe phenotype reflects many previous research findings into EGFR

Orientia tsutsugamushi (8,204 words) [view diff] exact match in snippet view article find links to article

of Rickettsia rickettsii, Rickettsia parkeri, and Rickettsia akari in skin biopsy specimens using a multiplex real-time polymerase chain reaction assay"

Induced pluripotent stem cell (10,679 words) [view diff] exact match in snippet view article find links to article

lentiviral system. Obtaining fibroblasts to produce iPSCs involves a skin biopsy, and there has been a push towards identifying cell types that are more

Peripheral mononeuropathy (2,215 words) [view diff] exact match in snippet view article find links to article

Imaging tests Nerve function tests Other nerve function tests Nerve biopsy Skin biopsy Medications: Pain relievers Anti-seizure medications Topical treatments

Dukes' disease (4,145 words) [view diff] exact match in snippet view article find links to article

rashes should only be used for reference. To confirm Dukes' disease, a skin biopsy and culture examination may be needed. Biopsy of skin samples can be

Sensory neuronopathy (1,331 words) [view diff] exact match in snippet view article find links to article

technically difficult to complete, only sometimes being done on autopsy. A skin biopsy may show decreased density of nerve fibers, but this is rarely needed

Migaloo (1,760 words) [view diff] exact match in snippet view article find links to article

from the Australian Marine Mammal Centre analyzed sloughed skin and skin biopsy samples from Migaloo in order to find the cause of the white appearance

Canine demodicosis (2,427 words) [view diff] exact match in snippet view article find links to article

("hair pluck"), squeezing out the hair follicles or with a clamp or a skin biopsy, for subsequent microscopic examination. Skin biopsies are particularly

Muse cell (8,806 words) [view diff] exact match in snippet view article find links to article

clinics. They can also be isolated from skin fibroblasts obtained via skin biopsy, adipose tissue obtained by liposuction and from the umbilical cord;