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searching for SOX2 47 found (147 total)

alternate case: sOX2

Darzens halogenation (281 words) [view diff] exact match in snippet view article find links to article

treatment upon reflux of a large excess of thionyl chloride or thionyl bromide (SOX2) in the presence of a small amount of a nitrogen base, such as a tertiary

Examples of in vitro transdifferentiation by initial epigenetic activation phase approach (273 words) [view diff] case mismatch in snippet view article find links to article

fibroblasts → cardiomyocytes (Oct4, Sox2, Klf4, JI1 and Bmp4) Fibroblasts → neural stem/progenitor cells (Oct4, Sox2, c-Myc, Klf4) Transdifferentiation

Inner cell mass (1,750 words) [view diff] case mismatch in snippet view article find links to article

do not turn on the Cdx2 gene, and express high levels of Oct4, Nanog, and Sox2. These genes suppress Cdx2 and the inside cells maintain pluripotency generate

Septo-optic dysplasia (1,074 words) [view diff] exact match in snippet view article find links to article

affected. In addition to HESX1, mutations in OTX2, SOX2 and PAX6 have been implicated in SOD. SOX2 mutations in SOD patients are associated with severe

RNA22 (769 words) [view diff] case mismatch in snippet view article find links to article

"non-canonical" microRNA targets in the coding regions of the mouse Nanog, Oct4 and Sox2. Most of these targets are not conserved in the human orthologues of these

MiR-296 (436 words) [view diff] case mismatch in snippet view article find links to article

Thomson AM, Lim B, Rigoutsos I (October 2008). "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation". Nature. 455

Epiblast-derived stem cell (968 words) [view diff] case mismatch in snippet view article find links to article

overexpressing in the primed pluripotent stem cell a reprogramming factor Klf4, or Sox2 and Klf4 (SK cocktail). Klf4 alone can reset mouse primed cells, but SK is

Renal stem cell (700 words) [view diff] case mismatch in snippet view article find links to article

induced pluripotent stem cells by the treatment of only two factors - Oct4 and Sox2. List of human cell types derived from the germ layers Brodie, J. C.; Humes

Dental pulp stem cell (2,474 words) [view diff] exact match in snippet view article find links to article

pluripotent-like stem cells (DPPSC). These cells are SSEA4+, OCT3/4+, NANOG+, SOX2+, LIN28+, CD13+, CD105+, CD34-, CD45-, CD90+, CD29+, CD73+, STRO1+, and CD146-

FGF4 (1,874 words) [view diff] case mismatch in snippet view article find links to article

"Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3". Genes & Development. 9 (21): 2635–2645. doi:10.1101/gad.9.21

Actinopterygii (3,758 words) [view diff] case mismatch in snippet view article find links to article

Sanketi, Bhargav; Kurpios, Natasza; McCune, Amy (2020). "Changing in Nkx2.1, Sox2, Bmp4, and Bmp16 expression underlying the lung-to-gas bladder evolutionary

Ectoderm specification (2,122 words) [view diff] case mismatch in snippet view article find links to article

blastula embryos for an expansion of the region of the ectodermal marker Sox2 and diminution of the expression of the mesodermal marker Xbra. Ectodermin

Artificial transcription factor (1,698 words) [view diff] case mismatch in snippet view article find links to article

The field gained significant interest once four transcription factors Oct4/Sox2/cMyc/Klf4 were found to reprogram cells from a differentiated state into

Ewing sarcoma (4,387 words) [view diff] exact match in snippet view article find links to article

expression levels of both receptors. A recent study also suggested a role for SOX2 as an independent prognostic biomarker that can be used to identify patients

Mir-145 (1,481 words) [view diff] exact match in snippet view article find links to article

Papagiannakopoulos T, Pan G, et al. (May 2009). "MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells". Cell

EHMT1 (1,596 words) [view diff] case mismatch in snippet view article find links to article

(2015-10-22). "Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein Stability". PLOS ONE. 10 (10): e0141118. Bibcode:2015PLoSO..1041118L

Pituitary gland (3,466 words) [view diff] case mismatch in snippet view article find links to article

Tulsidas; Pevny, Larysa Halyna; Martinez-Barbera, Juan Pedro (October 2013). "Sox2+ Stem/Progenitor Cells in the Adult Mouse Pituitary Support Organ Homeostasis

Ventricular zone (725 words) [view diff] case mismatch in snippet view article find links to article

The VZ and SVZ are indicated by immunohistochemical labelling of Sox2 and Tbr2 gene expression in the embryonic mouse forebrain at embryonic day 13.5.

Magdalena Żernicka-Goetz (2,214 words) [view diff] case mismatch in snippet view article find links to article

T, Marioni JC, Zernicka-Goetz M (March 2016). "Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos". Cell. 165 (1): 61–74.

Protein filament (1,806 words) [view diff] case mismatch in snippet view article find links to article

Human neural stem cells stained for Sox2, in green, and vimentin, in red. Vimentin is a type III intermediate filament (IF) protein.

Cord lining (1,087 words) [view diff] exact match in snippet view article find links to article

EpSC exhibit classical pluripotent stem cell markers such as SSEA-4, Oct-4, SOX2 and Nanog. They also express p63, a specific marker of epithelial progenitor

Negro Southern League (1920–1936) (1,455 words) [view diff] case mismatch in snippet view article

Montgomery Grey Sox, 4g-1g 1926: Birmingham Black Barons1 defeated Memphis Red Sox2, 5g-2g (3 ties) 1932: Cole's American Giants1 defeated Nashville Elite Giants2

Mir-16 microRNA precursor family (2,695 words) [view diff] case mismatch in snippet view article find links to article

J, Thomson AM, Lim B, Rigoutsos I (2008). "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation". Nature. 455

Dentition (3,652 words) [view diff] case mismatch in snippet view article find links to article

doi:10.1002/bies.200900151. PMC 3034446. PMID 20730948. Martin et al. (2016) Sox2+ progenitors in sharks link taste development with the evolution of regenerative

Halibut (3,412 words) [view diff] case mismatch in snippet view article find links to article

halibut is located on chromosome 9 and it is likely to be bmpr1ba. The gene sox2 is likely to play the same role in the Greenland halibut. The North Pacific

Transflammation (690 words) [view diff] case mismatch in snippet view article find links to article

fibroblast using a retroviral construct with the transcription factors Oct3/4, Sox2, c-Myc and Klf4 according to Takahashi, Yamanaka. However, these vectors

Kenneth S. Kosik (478 words) [view diff] exact match in snippet view article find links to article

G; Thomson, J. A.; Kosik, K. S. (May 2009). "MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells". Cell

TMEM247 (1,461 words) [view diff] case mismatch in snippet view article find links to article

development-related binding sites, such as pluripotent stem cell related factors (Oct4, Sox2, Nanog), sex-determining HMG box factors, and various homeobox/homeodomain

Mesenchymal–epithelial transition (1,600 words) [view diff] case mismatch in snippet view article find links to article

cell reprogramming, can be achieved by ectopic expression of Oct4, Klf4, Sox2, and c-Myc (OKSM). Upon induction, mouse fibroblasts must undergo MET to

Mir-452 microRNA precursor family (567 words) [view diff] exact match in snippet view article find links to article

Hua D, Zheng S, Hood L, Goodlett DR, Foltz G, Lin B (January 2011). "The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression

Requirements engineering tools (910 words) [view diff] exact match in snippet view article find links to article

Commercial Scrumwise x Commercial ScrumWorks Pro CollabNet x Commercial SOX2 RM Engineers Consulting GmbH x Commercial Specification Wizard MeetAdd x

Teleost (10,148 words) [view diff] case mismatch in snippet view article find links to article

C.; Sanketi, B. D.; Kurpios, N.; McCune, A. (2020). "Changes in Nkx2.1, Sox2, Bmp4, and Bmp16 expression underlying the lung-to-gas bladder evolutionary

Nicolas H. Thomä (1,658 words) [view diff] exact match in snippet view article find links to article

Lukas; Schübeler, Dirk; Thomä, Nicolas H. (26 June 2020). "Mechanisms of OCT4-SOX2 motif readout on nucleosomes". Science. 368 (6498): 1460–1465. Bibcode:2020Sci

Embryonic stem cell (8,675 words) [view diff] case mismatch in snippet view article find links to article

embryonic stem cells, can be induced by the delivery of four factors (Oct3/4, Sox2, c-Myc, and Klf4) to differentiated cells. Utilizing the four genes previously

Bing Li (academic) (2,443 words) [view diff] exact match in snippet view article

averting chemical-induced skin tumor development. By orchestrating the IFN/p53/SOX2 pathway in keratinocytes, FABP5 emerges as a promising candidate for augmenting

Pioneer factor (2,798 words) [view diff] case mismatch in snippet view article find links to article

"Epigenetic priming of a pre-B cell-specific enhancer through binding of Sox2 and Foxd3 at the ESC stage". Cell Stem Cell. 7 (1): 114–26. doi:10.1016/j

Placenta-specific protein 1 (3,777 words) [view diff] exact match in snippet view article find links to article

Hashimoto Y, Shimada S, Goto K, Yuasa Y (January 2011). "MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis". PLOS ONE. 6 (1): e16617

The Cancer Genome Atlas (7,468 words) [view diff] exact match in snippet view article find links to article

neck squamous cell carcinomas and had frequent amplifications of CCND1, SOX2 and TP63; adenocarcinomas were similar to chromosomally unstable gastric

Trevor K. Archer (699 words) [view diff] case mismatch in snippet view article find links to article

Trotter; Yoshihiro Komatsu; Yuji Mishina; Trevor K Archer (October 2008). "Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells". Molecular

Bernd Fritzsch (1,181 words) [view diff] case mismatch in snippet view article find links to article

Cheah, Kathryn S. E.; Pevny, Larysa H.; Kelley, Matthew W. (2008-11-25). "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation

Starfish regeneration (4,011 words) [view diff] case mismatch in snippet view article find links to article

larval sea star nervous system by wounding induced respecification to the Sox2 lineage". eLife. 11: e72983. doi:10.7554/eLife.72983. ISSN 2050-084X. PMC 8809897

2023 in science (44,592 words) [view diff] case mismatch in snippet view article find links to article

tasks. 7 December A gene therapy based on three transcription factors, Oct4, Sox2, and Klf4 (OSK), is shown to provide sustained vision recovery in mice affected

Epigenetic regulation of neurogenesis (8,185 words) [view diff] exact match in snippet view article find links to article

Ferguson KM, Bressan RB, Blin C, et al. (April 2017). "Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional

Murine respirovirus (32,094 words) [view diff] exact match in snippet view article find links to article

a cell line. Temperature sensitive mutants of SeV encoding human OCT3/4, SOX2, KLF4 and c-MYC genes are used to infect human donor cells, but the resulting

Non-arteritic anterior ischemic optic neuropathy (4,108 words) [view diff] case mismatch in snippet view article find links to article

that AAV2-induced transient expression of the reprogramming genes Oct4, Sox2, and Klf4 (OSK) could reverse retinal aging and restore visual function in

Myelinoid (4,912 words) [view diff] exact match in snippet view article find links to article

include a ventricular zone surrounding the cavity with cells expressing PAX6, SOX2 and Ki67, followed by the outer subventricular zone and intermediate zone

List of human transcription factors (81 words) [view diff] exact match in snippet view article find links to article

ENSG00000203883 HMG/Sox Known motif – High-throughput in vitro [849] ATCAATGHWATTGAT SOX2 ENSG00000181449 HMG/Sox Known motif – High-throughput in vitro [850] HATCAATANCATTGATH