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searching for Remyelination 51 found (71 total)

alternate case: remyelination

Oligodendrocyte progenitor cell (6,138 words) [view diff] exact match in snippet view article find links to article

morphological abnormalities, however, remyelination does restore normal conduction. In addition, spontaneous remyelination does not appear to be rare, at least
Demyelinating disease (2,779 words) [view diff] exact match in snippet view article find links to article
in regions of active remyelination and may play an important role in generating a local environment conducive to remyelination. N-cadherin agonists have
Cholesterol crystal (478 words) [view diff] exact match in snippet view article find links to article
macrophages is believed to be associated with multiple sclerosis, and this remyelination failure is particularly impaired in the elderly. Dowling RH (2000).
Neuroregeneration (3,247 words) [view diff] exact match in snippet view article find links to article
scars rapidly form, and the glia actually produce factors that inhibit remyelination and axon repair; for instance, NOGO and NI-35. The axons themselves
Véronique Miron (532 words) [view diff] exact match in snippet view article find links to article
therapies on oligodendroglial lineage cells, myelin maintenance, and remyelination". She then carried out her postdoctoral studies at the Centre for Regeneration
Cerebroside (700 words) [view diff] exact match in snippet view article find links to article
Cerebroside synthesis can therefore give a measurement of myelin formation or remyelination. The sugar moiety is linked glycosidically to the C-1 hydroxyl group
Paola Leone (269 words) [view diff] exact match in snippet view article find links to article
Cure to study the potential of subpopulations of stem cells to promote remyelination and phenotypic rescue in animal models of white matter disease, including
Montelukast (1,860 words) [view diff] exact match in snippet view article find links to article
pathway of leukotrienes.[citation needed] Montelukast may affect nerve remyelination in combination with Pexidartinib and this may cause clinical benefits
The Cyprus Institute of Neurology and Genetics (327 words) [view diff] exact match in snippet view article find links to article
disability of patients. Finally, it is also potentially able to trigger remyelination, neuroprotection and mainly free of side effects. It thus has the ability
Michael Fehlings (1,188 words) [view diff] exact match in snippet view article find links to article
neural stem cells in repairing/regenerating injured spinal cords through remyelination of axons. This finding has been key in leading clinical translational
Cyclin-dependent kinase 5 (5,367 words) [view diff] exact match in snippet view article find links to article
Multiple sclerosis (MS): is one of the diseases, in which a failure of remyelination can provoke lasting axonal damage and an irreversible loss of function
Glycolipid (1,594 words) [view diff] exact match in snippet view article find links to article
Morell P (May 2001). "Cerebroside synthesis as a measure of the rate of remyelination following cuprizone-induced demyelination in brain". Journal of Neurochemistry
Myelin regulatory factor (720 words) [view diff] exact match in snippet view article find links to article
in the myelin sheath. Further, the activity of MYRF increases during remyelination, suggesting it has a critical role in this process. Animals with repressed
Stinger (medicine) (1,870 words) [view diff] exact match in snippet view article
function involves demyelination. Axonal integrity is preserved, and remyelination occurs within days or weeks. Grade II is categorized by axonotmesis
Cerebrolysin (1,094 words) [view diff] exact match in snippet view article find links to article
Granatov, EV; Shakirzianova, SR (2016). "[Effect of cerebrolysin on remyelination processes in multiple sclerosis patients in stage of relapse regression]"
GPR17 (1,797 words) [view diff] exact match in snippet view article find links to article
protein-coupled receptor 17". Fumagalli M, Lecca D, Abbracchio MP (2016). "CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles
Ursolic acid (1,648 words) [view diff] exact match in snippet view article find links to article
treatment of multiple sclerosis through both immunomodulation and direct remyelination". Proceedings of the National Academy of Sciences. 117 (16): 9082–9093
Myelitis (2,486 words) [view diff] exact match in snippet view article find links to article
inflammation, to modulate the immune system, and to enhance regeneration and remyelination of axons. Neural stem cells (NSC) have the potential to integrate with
Gliotransmitter (2,116 words) [view diff] exact match in snippet view article find links to article
in sleep, cognition, synaptic function and plasticity, and promote remyelination and regeneration of injured nervous tissue. Other functions include
CXCL1 (1,546 words) [view diff] exact match in snippet view article find links to article
Santambrogio L, Lira SA, Raine CS (January 2009). "Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1"
Paclitaxel (5,943 words) [view diff] exact match in snippet view article find links to article
increase the number of microtubules in the cell. Paclitaxel induces remyelination in a demyelinating mouse in vivo and inhibits hPAD2 in vitro though
Glia (3,584 words) [view diff] exact match in snippet view article find links to article
(2020-07-09). "Macroglial diversity: white and grey areas and relevance to remyelination". Cellular and Molecular Life Sciences. 78 (1): 143–171. doi:10
Glial fibrillary acidic protein (3,082 words) [view diff] exact match in snippet view article find links to article
PMID 31881522. Bunge MB, Bunge RP, Ris H (May 1961). "Ultrastructural study of remyelination in an experimental lesion in adult cat spinal cord". The Journal of
Segesterone acetate (1,704 words) [view diff] exact match in snippet view article find links to article
et al. (October 2011). "Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors". Endocrinology. 152 (10): 3820–31
Pathology of multiple sclerosis (17,122 words) [view diff] exact match in snippet view article find links to article
astrogliosis, oligodendrocyte injury, neurodegeneration, axonal loss and remyelination. MS lesions evolve differently during early versus chronic disease phases
Biogen (3,255 words) [view diff] exact match in snippet view article find links to article
hurdle". Fierce Biotech. Retrieved 2013-04-08. "Lingo: a promising remyelination target in MS". Multiple Sclerosis Research. Retrieved 2014-06-16. "Isis
Biotin (4,926 words) [view diff] exact match in snippet view article find links to article
demyelinating autoimmune disease. The hypothesis is that biotin may promote remyelination of the myelin sheath of nerve cells, slowing or even reversing neurodegeneration
Eicosanoid receptor (2,886 words) [view diff] exact match in snippet view article find links to article
PMID 27863043. S2CID 10935349. Fumagalli M, Lecca D, Abbracchio MP (2016). "CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles
Prolactin (4,915 words) [view diff] exact match in snippet view article find links to article
VW, Weiss S (February 2007). "White matter plasticity and enhanced remyelination in the maternal CNS". The Journal of Neuroscience. 27 (8): 1812–23.
Neurodegeneration (6,164 words) [view diff] exact match in snippet view article find links to article
Teunissen, Charlotte (2008-07-08). "Faculty Opinions recommendation of Remyelination protects axons from demyelination-associated axon degeneration". Brain:
Coronavirus (10,481 words) [view diff] exact match in snippet view article find links to article
Whitman L, Lane TE (July 2010). "Cell replacement therapies to promote remyelination in a viral model of demyelination". Journal of Neuroimmunology. 224
Nerve injury (3,924 words) [view diff] exact match in snippet view article find links to article
Wenlong (2010). "Short-term low-frequency electrical stimulation enhanced remyelination of injured peripheral nerves by inducing the promyelination effect of
Krembil Research Institute (1,799 words) [view diff] exact match in snippet view article find links to article
"Delayed Transplantation of Adult Neural Precursor Cells Promotes Remyelination and Functional Neurological Recovery after Spinal Cord Injury". Journal
Phosphatidylinositol-4-phosphate 5-kinase (1,067 words) [view diff] exact match in snippet view article find links to article
is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS". Neuron. 85 (6): 1227–43. doi:10.1016/j.neuron.2015.02.024
Nerve growth factor (4,565 words) [view diff] exact match in snippet view article find links to article
1016/S0079-6123(03)46021-4. ISBN 9780444514721. PMID 14712791. Althaus HH (2004). "Remyelination in multiple sclerosis: a new role for neurotrophins?". Progress in Brain
Interleukin 6 (6,811 words) [view diff] exact match in snippet view article find links to article
neurons and, hence, may be important in nerve regeneration through remyelination. Interleukin-6 has been shown to interact with interleukin-6 receptor
Vitamin B12 (11,118 words) [view diff] exact match in snippet view article find links to article
Korem M, Almog R, Galboiz Y (June 2005). "Vitamin B12, demyelination, remyelination and repair in multiple sclerosis". Journal of the Neurological Sciences
Pathophysiology of multiple sclerosis (8,899 words) [view diff] exact match in snippet view article find links to article
Möbius W, Simons M (2018). "Defective cholesterol clearance limits remyelination in the aged central nervous system". Science. 359 (6376): 684–688. Bibcode:2018Sci
Murine coronavirus (4,362 words) [view diff] exact match in snippet view article find links to article
Whitman L, Lane TE (July 2010). "Cell replacement therapies to promote remyelination in a viral model of demyelination". Journal of Neuroimmunology. 224
Multiple sclerosis drug pipeline (9,134 words) [view diff] exact match in snippet view article find links to article
PMC 6100297. PMID 30150982. Neumann B, et al. (2019). "Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells". Cell Stem Cell. 25 (4): 473–485
Glutamate receptor (6,393 words) [view diff] exact match in snippet view article find links to article
influx. The experiments showed improved oligodendrocyte survival, and remyelination increased. Furthermore, CNS inflammation, apoptosis, and axonal damage
Stem-cell therapy (9,425 words) [view diff] exact match in snippet view article find links to article
Positive migration of the injected cells to the site of lesion, increased remyelination detected by Myelin Basic Proteins, positive differentiation into Olig2
Κ-opioid receptor (7,289 words) [view diff] exact match in snippet view article find links to article
VW, Weiss S (February 2007). "White matter plasticity and enhanced remyelination in the maternal CNS". The Journal of Neuroscience. 27 (8): 1812–23.
Lesional demyelinations of the central nervous system (4,831 words) [view diff] exact match in snippet view article find links to article
plaques or lesions usually reported in MS. A repair process, called remyelination, takes place in early phases of the disease, but the oligodendrocytes
Reticulon 4 (1,909 words) [view diff] exact match in snippet view article find links to article
Vinters HV, et al. (December 2016). "Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery
Transforming growth factor beta (8,601 words) [view diff] exact match in snippet view article find links to article
growth. Hence, the decreased TGF-β levels during MS may also prevent remyelination of neurons. Higher concentrations of TGF-β are found in the blood and
Sammy Lee (scientist) (2,426 words) [view diff] exact match in snippet view article
reproduction. He was attached to the Jessen-Mirsky laboratory and was studying remyelination. Lee had ethical committee approval in Brasil for creating artificial
Hes3 signaling axis (3,337 words) [view diff] exact match in snippet view article find links to article
expression in the adult mouse brain is regulated during demyelination and remyelination". Brain Research. 1642: 124–30. doi:10.1016/j.brainres.2016.03.014.
Katerina Akassoglou (1,877 words) [view diff] exact match in snippet view article find links to article
Strickland, Sidney (2002-03-14). "Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation". Neuron. 33 (6): 861–875
Patrizia Casaccia (2,605 words) [view diff] exact match in snippet view article find links to article
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency (News and Views and Highlights in Nature Neuroscience Reviews)
Multiple sclerosis biomarkers (7,716 words) [view diff] exact match in snippet view article find links to article
loss dominates in the T1 hypointense core and that the effects of de/remyelination may be better detected in the "T2-rim", where there is relative preservation