Find link

language:

jump to random article

Find link is a tool written by Edward Betts.

searching for Rap1 75 found (92 total)

alternate case: rap1

RAP1GAP (992 words) [view diff] exact match in snippet view article find links to article

Rap1 GTPase-activating protein 1 is an enzyme that in humans is encoded by the RAP1GAP gene. RAP1GAP has been shown to interact with MLLT4. GRCh38: Ensembl
RAP1GDS1 (573 words) [view diff] exact match in snippet view article find links to article
Rap1 GTPase-GDP dissociation stimulator 1 is an enzyme that in humans is encoded by the RAP1GDS1 gene. RAP1GDS1 has been shown to interact with KIFAP3
Dock4 (1,460 words) [view diff] exact match in snippet view article find links to article
activators of small G proteins. Dock4 activates the small G proteins Rac and Rap1. Dock4 was discovered as a gene product which was disrupted during tumour
RASSF5 (1,018 words) [view diff] exact match in snippet view article find links to article
Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or
APBB1IP (723 words) [view diff] exact match in snippet view article find links to article
1-interacting protein (APBB1IP), also known as APBB1-interacting protein 1 or Rap1-GTP-interacting adapter molecule (RIAM) is a protein that in humans is encoded
RAPGEF5 (525 words) [view diff] exact match in snippet view article find links to article
"Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1". FEBS Lett. 457 (1): 85–9. doi:10.1016/S0014-5793(99)01012-1. PMID 10486569
RAPGEF2 (854 words) [view diff] exact match in snippet view article find links to article
T, et al. (2007). "Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite
Crosstalk (biology) (1,656 words) [view diff] exact match in snippet view article
of PKA with Raf-1 or indirectly through PKA interaction with the GTPase Rap1 (see figure 1). PKA may also negatively regulate ERKs by the activation of
RAP2B (795 words) [view diff] exact match in snippet view article find links to article
PMID 2115998. Pizon V, Chardin P, Lerosey I, et al. (1988). "Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely
RAP1B (980 words) [view diff] case mismatch in snippet view article find links to article
PMID 18660803. S2CID 4393652. Gyan E, Frew M, Bowen D, et al. (2005). "Mutation in RAP1 is a rare event in myelodysplastic syndromes". Leukemia. 19 (9): 1678–80
Shelterin (2,151 words) [view diff] case mismatch in snippet view article find links to article
senescence, or apoptosis. Shelterin has six subunits: TRF1, TRF2, POT1, RAP1, TIN2, and TPP1. They can operate in smaller subsets to regulate the length
Telomere-binding protein (1,653 words) [view diff] case mismatch in snippet view article find links to article
telomere-binding protein complex known as shelterin: TERF1, TERF2, POT1, TIN2, RAP1 and TPP1. Both TERF1 and TERF2 bind the telomeric repeat sequences in the
RAPGEF1 (1,625 words) [view diff] exact match in snippet view article find links to article
Lai CF, Mobley WC (Aug 2001). "Nerve growth factor activates persistent Rap1 signaling in endosomes". The Journal of Neuroscience. 21 (15): 5406–16. doi:10
RAPGEF3 (3,410 words) [view diff] exact match in snippet view article find links to article
database search for proteins with sequence homology to both GEFs for Ras and Rap1 and to cAMP-binding sites, which led to the identification and subsequent
RAP2A (1,043 words) [view diff] exact match in snippet view article find links to article
V, Chardin P, Lerosey I, Olofsson B, Tavitian A (Aug 1988). "Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely
Telomeres in the cell cycle (2,663 words) [view diff] exact match in snippet view article find links to article
preventing checkpoint activation. Meanwhile, Rif2 and Rap1 inhibit NHEJ: knocking out Rif2 or Rap1 results in longer telomeres as measured by PCR, indicating
RAP1A (782 words) [view diff] exact match in snippet view article find links to article
2000). "Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction". The Journal of Biological
GAB1 (1,596 words) [view diff] exact match in snippet view article find links to article
"Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL". J. Biol
Nucleotide exchange factor (237 words) [view diff] exact match in snippet view article find links to article
Nijman; Alfred Wittinghofer; Johannes L. Bos (3 December 1998). "Epac is a Rap1 guanine- nucleotide-exchange factor directly activated by cyclic AMP" (PDF)
RGL2 (755 words) [view diff] exact match in snippet view article find links to article
"Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1". J. Biol. Chem. 271 (47): 29903–8. doi:10.1074/jbc.271.47.29903. PMID 8939933
RASSF2 (848 words) [view diff] exact match in snippet view article find links to article
activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating
SIR proteins (1,656 words) [view diff] exact match in snippet view article find links to article
factor) and Rap1 (repressor-activator protein) associate with specific nucleotide sequences in the silencers that flank heterochromatic regions. Rap1 contains
ChIP-exo (1,234 words) [view diff] exact match in snippet view article find links to article
analyses on a small collection of transcription factors: Reb1, Gal4, Phd1, Rap1 in yeast and CTCF in human. Reb1 sites were often found in clusters and these
Ravi Iyengar (2,197 words) [view diff] exact match in snippet view article find links to article
R (2005). "Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII"
Chromosome 17 (1,850 words) [view diff] case mismatch in snippet view article find links to article
QRICH2: encoding protein Glutamine-rich protein 2 RAP1GAP2: encoding protein RAP1 GTPase activating protein 2 RFFL: encoding enzyme E3 ubiquitin-protein ligase
TINF2 (1,071 words) [view diff] exact match in snippet view article find links to article
PMID 9373149. Li B, Oestreich S, de Lange T (May 2000). "Identification of human Rap1: implications for telomere evolution". Cell. 101 (5): 471–83. doi:10
PLCE1 (1,639 words) [view diff] exact match in snippet view article find links to article
the CDC25 homology domain of phospholipase Cepsilon in amplification of Rap1-dependent signaling". The Journal of Biological Chemistry. 276 (32): 30301–7
Enah/Vasp-like (909 words) [view diff] exact match in snippet view article find links to article
(2004). "RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion". Dev. Cell. 7 (4): 585–95. doi:10.1016/j.devcel
RGS17 (867 words) [view diff] exact match in snippet view article find links to article
1999). "Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein". The Journal of Biological Chemistry. 274 (31):
DOK4 (452 words) [view diff] exact match in snippet view article find links to article
regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase". J. Cell Sci. 119 (Pt 15): 3067–77
RADIL (574 words) [view diff] exact match in snippet view article find links to article
Rehmann H, Price LS, Riedl J, Bos JL (Sep 2005). "AF6 negatively regulates Rap1-induced cell adhesion". J Biol Chem. 280 (39): 33200–5. doi:10.1074/jbc.M505057200
CRKL (3,098 words) [view diff] exact match in snippet view article find links to article
"Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL". The Journal
RAPGEF6 (410 words) [view diff] exact match in snippet view article find links to article
of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2". Biochim. Biophys. Acta. 1593 (2–3): 141–149. doi:10.1016/S0167-4889(02)00365-8
SHB (gene) (1,016 words) [view diff] exact match in snippet view article
overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway". Experimental Cell Research. 259 (2): 370–7. doi:10.1006/excr.2000
Zinc finger and scan domain containing 4 (299 words) [view diff] exact match in snippet view article find links to article
PMID 20336070. Lee K, Gollahon LS (2014). "Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status". Cancer Biol. Ther. 15 (8):
Dock7 (1,180 words) [view diff] exact match in snippet view article find links to article
specific for Rho family G proteins Dock4 has been shown to bind and activate Rap1, which is not a member of the Rho family. This apparent promiscuity among
RAB27A (1,544 words) [view diff] exact match in snippet view article find links to article
molecular weights of 25,000 and 21,000 in human platelet cytosol. One is the rap1/smg21/Krev-1 protein and the other is a novel GTP-binding protein". J. Biol
GAB2 (3,184 words) [view diff] exact match in snippet view article find links to article
phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap1 GTPase". Immunological Reviews. 176: 47–68. doi:10.1034/j.1600-065X.2000
MTG1 (631 words) [view diff] exact match in snippet view article find links to article
of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2". Biochim. Biophys. Acta. 1593 (2–3): 141–9. doi:10.1016/S0167-4889(02)00365-8
GAB2 (3,184 words) [view diff] exact match in snippet view article find links to article
phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap1 GTPase". Immunological Reviews. 176: 47–68. doi:10.1034/j.1600-065X.2000
Telomere-associated protein RIF1 (520 words) [view diff] case mismatch in snippet view article find links to article
doi:10.1002/dvdy.10471. PMID 15042697. S2CID 22138565. "Entrez Gene: RIF1 RAP1 interacting factor homolog (yeast)". Ribeyre C, Shore D (2012). "Anticheckpoint
MAGI1 (1,308 words) [view diff] exact match in snippet view article find links to article
Y, Masuda M, Nakaoka Y, Mochizuki N (Feb 2006). "MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial
RASGRP3 (1,024 words) [view diff] exact match in snippet view article find links to article
2000). "Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction". The Journal of Biological
SH2D3C (976 words) [view diff] exact match in snippet view article find links to article
to be an important regulator of lymphocyte adhesion, acting upstream of Rap1 in the integrin activation pathway. GRCh38: Ensembl release 89: ENSG00000095370
KIDINS220 (747 words) [view diff] exact match in snippet view article find links to article
as a receptor for the CRKL-C3G complex. Binding this complex results in Rap1-dependent sustained ERK activation. This, in turn, interacts with several
ELOA (857 words) [view diff] exact match in snippet view article find links to article
PMID 12943681. Stoletov KV, Terman BI (2004). "Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation". Biochem. Biophys.
FAF1 (927 words) [view diff] exact match in snippet view article find links to article
1038/ng1285. PMID 14702039. Stoletov KV, Terman BI (2004). "Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation". Biochem. Biophys.
RALGDS (1,548 words) [view diff] exact match in snippet view article find links to article
Pessin JE (1998). "Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G
LifeAct Dye (745 words) [view diff] exact match in snippet view article find links to article
PMID 18536722. Sawant K, Chen Y, Kotian N, Preuss KM, McDonald JA (August 2018). "Rap1 GTPase promotes coordinated collective cell migration in vivo". Molecular
Telomeric repeat–containing RNA (4,625 words) [view diff] exact match in snippet view article find links to article
exonuclease Rat1 (human ortholog Xrn2) through interaction with the proteins Rap1 and Rif1/2. It remains unclear whether TERRA transcripts remain tethered
Mitotic cell rounding (1,423 words) [view diff] exact match in snippet view article find links to article
Caron, Emmanuelle; de Gunzburg, Jean (15 August 2009). "Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis".
NEDD9 (7,975 words) [view diff] case mismatch in snippet view article find links to article
addition, in response to chemokine signals, Abl family kinases promote GTPase RAP1 activation by phosphorylating of NEDD9; NEDD9 associates with the transducer
George Santangelo (319 words) [view diff] exact match in snippet view article find links to article
2005). "Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation". Proceedings of the National Academy
Afadin (1,979 words) [view diff] exact match in snippet view article find links to article
(Apr 2003). "AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1". The Journal
Rad50 (2,166 words) [view diff] exact match in snippet view article find links to article
PMID 11096100. O'Connor MS, Safari A, Liu D, Qin J, Songyang Z (2004). "The human Rap1 protein complex and modulation of telomere length". J. Biol. Chem. 279 (27):
RABGEF1 (864 words) [view diff] case mismatch in snippet view article find links to article
RABGEF1 Identifiers Aliases RABGEF1, RABEX5, RAP1, rabex-5, RAB guanine nucleotide exchange factor 1 External IDs OMIM: 609700 MGI: 1929459 HomoloGene:
The Wurzels (2,616 words) [view diff] case mismatch in snippet view article find links to article
1982 John Miles JM1009 "Wurzel Rap" / "Wurzels in Stereo" 1983 Goldliner RAP1 "All Fall Down" / "My Somerset Crumpet Horn" 1986 Dingles SID238 "Sunny Weston-super-Mare"
KRIT1 (1,389 words) [view diff] exact match in snippet view article find links to article
Glading A, Han J, Stockton RA, Ginsberg MH (Oct 2007). "KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions". The Journal of
SKAP1 (1,198 words) [view diff] exact match in snippet view article find links to article
receptor-mediated integrin activation through plasma membrane targeting of Rap1". Molecular and Cellular Biology. 26 (19): 7130–44. doi:10.1128/MCB.00331-06
DAB1 (1,845 words) [view diff] exact match in snippet view article find links to article
Ballif BA, Arnaud L, Arthur WT, et al. (2004). "Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons". Curr. Biol. 14 (7): 606–10. doi:10
Beat Fierz (1,142 words) [view diff] exact match in snippet view article find links to article
(2020-02-06). "Chromatin Fiber Invasion and Nucleosome Displacement by the Rap1 Transcription Factor". Molecular Cell. 77 (3): 488–500.e9. doi:10.1016/j
Alveolar macrophage (3,810 words) [view diff] exact match in snippet view article find links to article
"Effects of prostaglandin E2 on the subcellular localization of Epac-1 and Rap1 proteins during Fcgamma-receptor-mediated phagocytosis in alveolar macrophages"
Johanna Ivaska (876 words) [view diff] exact match in snippet view article find links to article
"SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras". Nature Cell Biology. 19 (4): 292–305. doi:10.1038/ncb3487. ISSN 1465-7392
Ku80 (2,554 words) [view diff] exact match in snippet view article find links to article
O'Connor MS, Safari A, Liu D, Qin J, Songyang Z (July 2004). "The human Rap1 protein complex and modulation of telomere length". J. Biol. Chem. 279 (27):
Junctional adhesion molecule (1,814 words) [view diff] exact match in snippet view article find links to article
epithelial cells by moderating expression of β1 integrin protein downstream of Rap1. JAM-1 has been shown to be able to cause cell adhesion, spreading and movement
ChIP-on-chip (2,934 words) [view diff] exact match in snippet view article find links to article
J.D. Lieb, X. Liu, D. Botstein, P.O. Brown, Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association, Nat. Genet. 28 (2001)
C-Raf (8,625 words) [view diff] exact match in snippet view article find links to article
interaction in high detail in the PDB box attached to the article. It shows Rap1 in complex with the RBD of c-Raf.) The C1 domain - immediately downstream
List of MeSH codes (D12.776.476) (1,240 words) [view diff] exact match in snippet view article
476.525.400.200 – rab5 gtp-binding proteins MeSH D12.776.476.525.475.100 – rap1 gtp-binding proteins MeSH D12.776.476.525.500.300 – oncogene protein p21(ras)
Eric J. Nestler (3,467 words) [view diff] exact match in snippet view article find links to article
Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling". Neuron. 89 (3): 566–582. doi:10.1016/j.neuron.2016
List of MeSH codes (D12.644) (5,787 words) [view diff] exact match in snippet view article
644.360.525.475 – rap gtp-binding proteins MeSH D12.644.360.525.475.100 – rap1 gtp-binding proteins MeSH D12.644.360.525.500 – ras proteins MeSH D12.644
List of MeSH codes (D12.776.157) (4,484 words) [view diff] exact match in snippet view article
325.515.475 – rap gtp-binding proteins MeSH D12.776.157.325.515.475.100 – rap1 gtp-binding proteins MeSH D12.776.157.325.515.500 – ras proteins MeSH D12
MAP4K4 (3,255 words) [view diff] exact match in snippet view article find links to article
Pannekoek WJ, Linnemann JR, Brouwer PM, Bos JL, Rehmann H (2013-02-28). "Rap1 and Rap2 antagonistically control endothelial barrier resistance". PLOS ONE
Reelin (15,619 words) [view diff] exact match in snippet view article find links to article
Guris D, Imamoto A, Cooper JA (April 2004). "Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons". Current Biology. 14 (7): 606–10. doi:10
RBM10 (5,513 words) [view diff] case mismatch in snippet view article find links to article
(June 2019). "RBM10 inhibits cell proliferation of lung adenocarcinoma via RAP1/AKT/CREB signalling pathway". Journal of Cellular and Molecular Medicine
List of MeSH codes (D08) (15,232 words) [view diff] exact match in snippet view article
475 – rap gtp-binding proteins MeSH D08.811.277.040.330.300.400.475.100 – rap1 gtp-binding proteins MeSH D08.811.277.040.330.300.400.500 – ras proteins