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Longer titles found: Protomeroleuca (view), Protomerulius (view)

searching for Protomer 31 found (57 total)

alternate case: protomer

Muscarinic toxin 7 (214 words) [view diff] exact match in snippet view article find links to article

tips of MT7 loops II and III contacting one hM1 protomer and the tip of loop I binds to the other protomer. Fruchart-Gaillard C, Mourier G, Marquer C, Stura

Deoxyribonuclease (3,220 words) [view diff] exact match in snippet view article find links to article

structure consists of protomer A (cyan) and protomer B (green). Each structure consists of two catalytic motifs, which are labeled on protomer B for simplicity:

Type IV collagen C4 domain (381 words) [view diff] exact match in snippet view article find links to article

assembly, the C4 trimers of two protomers interact, forming a C4 hexamer structure, to select and connect protomers. The collagen IV C4 domain contains

Glutamate formimidoyltransferase (361 words) [view diff] exact match in snippet view article find links to article

formiminotransferase-cyclodeaminase (FTCD) forms a homodimer, with each protomer comprising two subdomains. The formiminotransferase domain has an N-terminal

Chance and Necessity (4,855 words) [view diff] exact match in snippet view article find links to article

(made up of identical protomer subunits) and each protomer has a receptor for each of the ligands. As a consequence of protomer assembly, each subunit

GPRC5D (492 words) [view diff] exact match in snippet view article find links to article

form of GPRC5D. Talquetamab Fab recognizes ECLs and TM3/5/7 of one GPRC5D protomer via six CDRs. The protein encoded by this gene is a member of the G protein-coupled

Site-specific recombination (2,034 words) [view diff] exact match in snippet view article find links to article

individual recombinase subunits ("protomers"; gray ovals) with the respective target site. Its formation depends on inter-protomer contacts and DNA bending, which

Batai orthobunyavirus (2,288 words) [view diff] exact match in snippet view article find links to article

were found to interact with neighboring NP protomers to form a tetrameric ring-shaped organization. Each protomer bound a 10-nucleotide RNA molecule, which

ClpX (1,594 words) [view diff] exact match in snippet view article find links to article

with two consecutive AAA modules per protomer(ClpA, ClpC, and ClpE) and class II with only one AAA module per protomer. ClpA and ClpX of E. coli are protein

SMC protein (1,485 words) [view diff] exact match in snippet view article find links to article

with two long coiled-coil arms. To make such a unique structure, an SMC protomer is self-folded through anti-parallel coiled-coil interactions, forming

Pertussis toxin (2,587 words) [view diff] exact match in snippet view article find links to article

endoplasmic reticulum. At some point during this transport, the A subunit (or protomer) becomes activated, perhaps through the action of glutathione and ATP.

Lisuride (2,110 words) [view diff] exact match in snippet view article find links to article

from biased agonism of the 5-HT2A receptor. Stimulation of the 5-HT2A protomer within the 5-HT2A–mGlu2 receptor complex evokes psychedelic effects, while

Acetoacetate decarboxylase (2,341 words) [view diff] exact match in snippet view article find links to article

β-barrel. The core of this β-barrel surrounds the active site in each protomer of the enzyme. The active site, consisting of residues such as Phe27, Met97

Eli Lilly and Company (15,000 words) [view diff] exact match in snippet view article find links to article

cell lung cancer. In July 2021, the company announced it would acquire Protomer Technologies for more than $1 billion. In January 2022, distribution of

Hydrogen potassium ATPase (2,351 words) [view diff] exact match in snippet view article find links to article

the Ca2+ and the Na+/K+ ATPases, the H+/K+ ATPase functions as an α, β protomer. Unlike other eukaryotic ATPases, the H+/K+ ATPase is electroneutral, transporting

Glucagon (2,990 words) [view diff] exact match in snippet view article find links to article

carboxylase. Interrelationship of the effects of phosphorylation, polymer-protomer transition, and citrate on enzyme activity". The Journal of Biological

MEP1A (1,059 words) [view diff] exact match in snippet view article find links to article

secreted meprin A metalloproteinase and characterization of the functional protomer". J. Biol. Chem. 276 (25): 23207–11. doi:10.1074/jbc.M102654200. PMID 11301339

Glutamate transporter (2,828 words) [view diff] exact match in snippet view article find links to article

retina. Like all glutamate transporters, EAATs are trimers, with each protomer consisting of two domains : the central scaffold domain (Figure 1A, wheat)

Protein kinase R (4,183 words) [view diff] exact match in snippet view article find links to article

reactions. It is not yet established whether PKR activates in cis, with a protomer's activation loop reaching into its own catalytic site, or in trans, with

Stimulator of interferon genes (2,748 words) [view diff] exact match in snippet view article find links to article

butterfly, with a deep cleft between the two protomers. The hydrophobic residues from each STING protomer form hydrophobic interactions between each other

MAP4 (1,156 words) [view diff] exact match in snippet view article find links to article

JC (1999). "Microtubule-associated protein 4 (MAP4) regulates assembly, protomer-polymer partitioning and synthesis of tubulin in cultured cells". J. Cell

Site-specific recombinase technology (3,200 words) [view diff] exact match in snippet view article find links to article

available with three arms, each accommodating a Flp unit (a so-called "protomer"). attP- and attB-sites follow similar architectural rules, but here the

Cluster of Excellence Frankfurt Macromolecular Complexes (15,449 words) [view diff] exact match in snippet view article find links to article

"Photocycle-dependent conformational changes in the proteorhodopsin cross-protomer Asp-His-Trp triad revealed by DNP-enhanced MAS-NMR". Proc Natl Acad Sci

Derlin-1 (2,259 words) [view diff] exact match in snippet view article find links to article

as a permeation pathway for misfolded protein substrates in ERAD. Each protomer in human Derlin-1 tetramer shares a high structural similarity with yeast

Catenin beta-1 (12,347 words) [view diff] exact match in snippet view article find links to article

polyposis coli (APC) protein contains 11 such motifs in tandem arrangement per protomer, thus capable to interact with several β-catenin molecules at once. Since

TRPV6 (10,475 words) [view diff] exact match in snippet view article find links to article

(538TIID541) containing four Aspartate 541 (D541) side chains (one from each protomer) is critical for Ca2+ selectivity and other biophysical properties of the

Cooperative binding (5,539 words) [view diff] exact match in snippet view article find links to article

1969, Wyman proposed such a model with "mixed conformations" (i.e. some protomers in the R state, some in the T state) for respiratory proteins in invertebrates

Origin of replication (12,561 words) [view diff] exact match in snippet view article find links to article

bent in oriC and folds back onto the initiator filament so that DnaA protomers simultaneously engage double- and single-stranded DNA regions. Elucidating

D domain (1,194 words) [view diff] exact match in snippet view article find links to article

suprafacial configuration which is observed between E2-site of every SCF protomer and the substrate-binding site. D-domain is also involved in the self-efficient

BBSome (6,700 words) [view diff] exact match in snippet view article find links to article

(A) Domain architecture of the protomers forming the BBSome core complex. The parts of the primary structure that could be assigned in the density is

Talquetamab (1,157 words) [view diff] exact match in snippet view article find links to article

extracellular surface of GPRC5D and recognizes ECLs and TM3/5/7 of one GPRC5D protomer via six CDRs. Efficacy was evaluated in MMY1001 (MonumenTAL-1) (NCT03399799