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Longer titles found: Cleavage and polyadenylation specificity factor (view), Cytoplasmic polyadenylation element (view), U1A polyadenylation inhibition element (PIE) (view), Simian virus 40 late polyadenylation signal (SVLPA) (view)

searching for Polyadenylation 184 found (361 total)

alternate case: polyadenylation

TLR 1 (582 words) [view diff] exact match in snippet view article find links to article

Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene
GNGT2 (533 words) [view diff] exact match in snippet view article find links to article
localized specifically in cones. There is evidence for use of multiple polyadenylation sites by this gene. GRCh38: Ensembl release 89: ENSG00000167083 - Ensembl
Collagen, type I, alpha 2 (426 words) [view diff] exact match in snippet view article find links to article
less abundant. Multiple messages for this gene result from multiple polyadenylation signals, a feature shared by most of the other collagen genes. Type-I
KLK15 (740 words) [view diff] exact match in snippet view article find links to article
prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants
DAPK2 (688 words) [view diff] exact match in snippet view article find links to article
of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. The DAPK2 mRNA may undergo alternative splicing to produce a
RFX2 (695 words) [view diff] exact match in snippet view article find links to article
been described for this gene, and both variants utilize alternative polyadenylation sites. GRCh38: Ensembl release 89: ENSG00000087903 - Ensembl, May 2017
CPSF1 (1,014 words) [view diff] exact match in snippet view article find links to article
Cleavage and polyadenylation specificity factor subunit 1 is a protein that in humans is encoded by the CPSF1 gene. In most cases eukaryotic pre-messenger(m)RNA
SYMPK (1,220 words) [view diff] exact match in snippet view article find links to article
regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery
CPSF6 (906 words) [view diff] exact match in snippet view article find links to article
Cleavage and polyadenylation specificity factor subunit 6 is a protein that in humans is encoded by the CPSF6 gene. The protein encoded by this gene is
NUDT21 (927 words) [view diff] exact match in snippet view article find links to article
Cleavage and polyadenylation specificity factor subunit 5 (CPSF5) is an enzyme that in humans is encoded by the NUDT21 gene. It belongs to the Nudix family
HPS4 (774 words) [view diff] exact match in snippet view article find links to article
this gene. In addition, transcript variants utilizing alternative polyadenylation signals exist. In melanocytic cells HPS4 gene expression may be regulated
CPSF3 (1,077 words) [view diff] exact match in snippet view article find links to article
Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene. Model organisms have been used in
CPSF2 (904 words) [view diff] exact match in snippet view article find links to article
Cleavage and polyadenylation specificity factor subunit 2 is a protein that in humans is encoded by the CPSF2 gene. GRCh38: Ensembl release 89: ENSG00000165934
Collagen, type IV, alpha 4 (920 words) [view diff] exact match in snippet view article find links to article
identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR. LOVD Alport gene variant databases (COL4A4
AP1B1 (1,128 words) [view diff] exact match in snippet view article find links to article
have been found for this gene, and variants utilizing alternative polyadenylation signals exist. AP1B1 has been shown to interact with KIF13A and AP1G1
ATP6V1A (695 words) [view diff] exact match in snippet view article find links to article
found in all tissues. Transcript variants derived from alternative polyadenylation exist. GRCh38: Ensembl release 89: ENSG00000114573 - Ensembl, May 2017
MAGEH1 (490 words) [view diff] exact match in snippet view article find links to article
MAGEH1 gene. This gene is thought to be involved in apoptosis. Multiple polyadenylation sites have been found for this gene. MAGEH1 has been shown to interact
PAPOLA (891 words) [view diff] exact match in snippet view article find links to article
interacting with PAPOLA and CPSF1), a subunit of the cleavage and polyadenylation specificity factor subunit 1 (CPSF1) complex. This complex polyadenylates
Exosome component 10 (830 words) [view diff] exact match in snippet view article find links to article
nuclear polyadenylation-dependent snoRNA catabolic process • nuclear polyadenylation-dependent snRNA catabolic process • nuclear polyadenylation-dependent
CSTF2T (718 words) [view diff] exact match in snippet view article find links to article
CC (Oct 2002). "The gene CSTF2T, encoding the human variant CstF-64 polyadenylation protein tauCstF-64, lacks introns and may be associated with male sterility"
GMEB2 (521 words) [view diff] exact match in snippet view article find links to article
glucocorticoid response elements. This gene appears to use multiple polyadenylation sites. GRCh38: Ensembl release 89: ENSG00000101216 - Ensembl, May 2017
Small nuclear ribonucleoprotein polypeptide A (1,068 words) [view diff] exact match in snippet view article find links to article
required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation". Molecular and Cellular Biology. 20 (6): 2209–17. doi:10.1128/MCB
APPBP2 (555 words) [view diff] exact match in snippet view article find links to article
gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. APPBP2 has been shown to interact
Cathepsin S (2,241 words) [view diff] exact match in snippet view article find links to article
encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Cathepsin S is a member of the peptidase
LRPPRC (961 words) [view diff] exact match in snippet view article find links to article
Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene. This gene encodes a protein that
GP1BB (1,397 words) [view diff] exact match in snippet view article find links to article
separate gene (septin 5) located upstream of this gene. In the absence of polyadenylation from its own imperfect site, the septin 5 gene uses the consensus polyA
LYPLA1 (553 words) [view diff] exact match in snippet view article find links to article
lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced
HSD17B6 (554 words) [view diff] exact match in snippet view article find links to article
retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. GRCh38: Ensembl release 89: ENSG00000025423 - Ensembl
FUT5 (461 words) [view diff] exact match in snippet view article find links to article
3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms". The Journal of Biological Chemistry. 270 (34): 20112–22
SURF4 (647 words) [view diff] exact match in snippet view article find links to article
glycosylated pro-alpha-factor into COPII vesicles. This gene uses multiple polyadenylation sites, resulting in transcript length variation. The existence of alternatively
TBL3 (409 words) [view diff] exact match in snippet view article find links to article
in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants
ESM1 (706 words) [view diff] exact match in snippet view article find links to article
endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. The ESM-1 gene product is also called
Exosome component 7 (687 words) [view diff] exact match in snippet view article find links to article
nuclear polyadenylation-dependent rRNA catabolic process • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent
RBM8A (1,257 words) [view diff] exact match in snippet view article find links to article
result in two forms of the protein, and this gene also uses multiple polyadenylation sites. RBM8A has been shown to interact with IPO13, MAGOH and UPF3A
James L. Manley (354 words) [view diff] exact match in snippet view article find links to article
colleagues identified and characterized the key factors responsible for polyadenylation of mRNA precursors, and elucidated how this remarkably complex machinery
PCDHB7 (588 words) [view diff] exact match in snippet view article find links to article
The transcript for this particular family member uses more than one polyadenylation site. GRCh38: Ensembl release 89: ENSG00000113212 - Ensembl, May 2017
Mir-711 microRNA precursor family (283 words) [view diff] exact match in snippet view article find links to article
regulation of Hsp70.3 gene expression by microRNA and alternative polyadenylation". The Journal of Biological Chemistry. 286 (34): 29828–37. doi:10.1074/jbc
GNB1 (1,207 words) [view diff] exact match in snippet view article find links to article
signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. Click on genes, proteins and metabolites below to link to
NXT1 (783 words) [view diff] exact match in snippet view article find links to article
of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. GRCh38: Ensembl release 89: ENSG00000132661
Exosome component 8 (595 words) [view diff] exact match in snippet view article find links to article
nuclear polyadenylation-dependent rRNA catabolic process • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent
Exosome component 9 (765 words) [view diff] exact match in snippet view article find links to article
U5 snRNA 3'-end processing • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent mRNA catabolic process • rRNA
Exosome component 3 (682 words) [view diff] exact match in snippet view article find links to article
(RNase complex) • nucleolus • nucleoplasm Biological process • nuclear polyadenylation-dependent tRNA catabolic process • exonucleolytic trimming to generate
PUF60 (1,029 words) [view diff] exact match in snippet view article find links to article
encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. PUF60 has been shown to interact with U2AF2. ENSG00000274081
Exosome component 2 (1,039 words) [view diff] exact match in snippet view article find links to article
nucleolus Biological process • nuclear polyadenylation-dependent tRNA catabolic process • nuclear polyadenylation-dependent rRNA catabolic process • regulation
FIP1L1 (3,192 words) [view diff] exact match in snippet view article find links to article
diseases in three case reports. FIP1L1 is a subunit of the cleavage and polyadenylation specificity factor subunit 1 (CPSF1) complex that polyadenylates the
FUT6 (848 words) [view diff] exact match in snippet view article find links to article
3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms". J. Biol. Chem. 270 (34): 20112–22. doi:10.1074/jbc
Functional element SNPs database (1,430 words) [view diff] exact match in snippet view article find links to article
sites, splice sites, coding exons, introns, translation stop sites, polyadenylation signals, and 3' UTRs. People may reference this database for haplotype
ERG (gene) (2,303 words) [view diff] exact match in snippet view article
a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation". Science. 237 (4815): 635–9. Bibcode:1987Sci...237
HMGN4 (333 words) [view diff] exact match in snippet view article find links to article
from chromatin templates. Transcript variants utilizing alternative polyadenylation signals exist for this gene. High-mobility group GRCh38: Ensembl release
Vidarabine (1,936 words) [view diff] exact match in snippet view article find links to article
Vidarabine triphosphate (ara-ATP) also inhibits RNA polyadenylation; preventing polyadenylation essential for HIV-1 and other retroviruses; and S-adenosylhomocysteine
GIMAP5 (618 words) [view diff] exact match in snippet view article find links to article
Zucchelli M, Kivinen K, et al. (2007). "The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus". J. Med
WDR33 (562 words) [view diff] exact match in snippet view article find links to article
Molecular function • RNA binding Cellular component • mRNA cleavage and polyadenylation specificity factor complex • collagen trimer • nucleus • fibrillar
Exonuclease (1,418 words) [view diff] exact match in snippet view article find links to article
Xrn2) to degrade the newly formed transcript downstream, leaving the polyadenylation site and simultaneously shooting the polymerase. This process involves
INTS11 (517 words) [view diff] exact match in snippet view article find links to article
PMID 16239144. S2CID 18069461. "Entrez Gene: CPSF3L cleavage and polyadenylation specific factor 3-like". Human CPSF3L genome location and CPSF3L gene
Fucosyltransferase 3 (1,168 words) [view diff] exact match in snippet view article find links to article
3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms". The Journal of Biological Chemistry. 270 (34): 20112–22
HSF1 (2,411 words) [view diff] exact match in snippet view article find links to article
Park-Sarge OK, Sarge KD (March 2004). "HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin". The Journal of Biological Chemistry
TSPAN8 (627 words) [view diff] exact match in snippet view article find links to article
This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. Overall survival of ovarian cancer
GOT1 (790 words) [view diff] exact match in snippet view article find links to article
cytosolic aspartate aminotransferase mRNAs generated by alternative polyadenylation site selection". Biochemistry. 29 (22): 5293–9. doi:10.1021/bi00474a011
Anion exchange transporter (536 words) [view diff] exact match in snippet view article find links to article
Splice variants that use both alternate transcription initiation and polyadenylation sites have been described for this gene. Solute carrier family GRCh38:
DUSP4 (823 words) [view diff] exact match in snippet view article find links to article
isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. In melanocytic cells DUSP4 gene expression
Complement factor B (1,087 words) [view diff] exact match in snippet view article find links to article
includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement
SEPT5 (1,352 words) [view diff] exact match in snippet view article find links to article
utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream
GNRHR (955 words) [view diff] exact match in snippet view article find links to article
including multiple promoters, transcription initiation sites, and polyadenylation signals". Mol. Cell. Endocrinol. 107 (2): R1–8. doi:10.1016/0303-7207(94)03460-B
NFATC1 (1,097 words) [view diff] exact match in snippet view article find links to article
Berberich-Siebelt F, Schmitt E, Serfling E (Feb 1999). "Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells".
Circadian clock (4,518 words) [view diff] exact match in snippet view article find links to article
driving rhythmic protein expression were later reported, such as mRNA polyadenylation dynamics. Fustin[who?] and co-workers identified methylation of internal
CD63 (1,559 words) [view diff] exact match in snippet view article find links to article
gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in
NFATC1 (1,097 words) [view diff] exact match in snippet view article find links to article
Berberich-Siebelt F, Schmitt E, Serfling E (Feb 1999). "Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells".
LPAR1 (1,105 words) [view diff] exact match in snippet view article find links to article
differing in the N-terminal extracellular tail. In addition, an alternate polyadenylation site has been reported. LPAR1 gene has been detected progressively
Integromics (1,507 words) [view diff] exact match in snippet view article find links to article
serological material. 2011 Integromics´ publication in Cell describes novel polyadenylation genome-wide profiling, achieved using Integromics SeqSolve™ Next Generation
Chromosome 11 (1,777 words) [view diff] exact match in snippet view article find links to article
member 5 COMMD9: COMM domain-containing protein 9 CPSF7: Cleavage and polyadenylation specificity factor subunit 7 CPT1A: carnitine palmitoyltransferase
SNAP29 (1,308 words) [view diff] exact match in snippet view article find links to article
significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. Model organisms have been used
PAX7 (1,374 words) [view diff] exact match in snippet view article find links to article
of two protein isoforms of PAX7 is controlled by competing cleavage-polyadenylation and splicing". Gene. 342 (1): 107–12. doi:10.1016/j.gene.2004.07.030
Cyclin B2 (1,142 words) [view diff] exact match in snippet view article find links to article
EA (2002). "Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr
PDGFA (1,076 words) [view diff] exact match in snippet view article find links to article
heterogeneity generated by the use of alternative promoters and alternative polyadenylation sites". Growth Factors. 7 (3): 241–51. doi:10.3109/08977199209046928
ETS2 (1,420 words) [view diff] exact match in snippet view article find links to article
FE, Papas TS (Oct 1990). "Molecular organization and differential polyadenylation sites of the human ETS2 gene". Oncogene. 5 (10): 1521–7. PMID 2250910
Carnivore bocaparvovirus 1 (419 words) [view diff] exact match in snippet view article find links to article
which through the mechanism of alternative splicing and alternative polyadenylation two nonstructural proteins (NS1 and NP1) and two capsid proteins (VP1
CD59 (1,177 words) [view diff] exact match in snippet view article find links to article
and demonstration that discrete mRNAs are generated by alternative polyadenylation". J. Mol. Biol. 227 (3): 971–976. doi:10.1016/0022-2836(92)90239-G
Cyclin-dependent kinase 9 (1,391 words) [view diff] exact match in snippet view article find links to article
regulation of muscle cell differentiation • negative regulation of mRNA polyadenylation • DNA repair • cellular response to cytokine stimulus • positive regulation
XKR5 (41 words) [view diff] exact match in snippet view article find links to article
v t e PDB gallery 2d9n: Solution structure of CCCH type zinc-finger domain 2 in Cleavage and polyadenylation specificity factor
LEO1 (432 words) [view diff] exact match in snippet view article find links to article
differentiation • positive regulation of mRNA 3'-end processing • mRNA polyadenylation • endodermal cell fate commitment • Wnt signaling pathway • histone
ACVR1B (1,537 words) [view diff] exact match in snippet view article find links to article
receptor, composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression
CSNK1D (14,714 words) [view diff] exact match in snippet view article find links to article
variants. Based on software analysis of the mRNA sequences various polyadenylation patterns could be identified for the transcription variants . TV1 and
AHCYL1 (628 words) [view diff] exact match in snippet view article find links to article
transport • S-adenosylmethionine cycle • response to calcium ion • mRNA polyadenylation • one-carbon metabolic process • regulation of cardiac conduction •
ZNRD1-AS1 (183 words) [view diff] exact match in snippet view article find links to article
gene in the MHC class I region, undergoes alternative splicing and polyadenylation processes in testis". Immunogenetics. 47 (6): 491–496. doi:10.1007/s002510050388
ACTH receptor (2,277 words) [view diff] exact match in snippet view article find links to article
C, Durand P, Bégeot M (May 1997). "Presence of multiple functional polyadenylation signals in the 3′-untranslated region of human corticotropin receptor
Douglas Higgs (916 words) [view diff] exact match in snippet view article find links to article
Weatherall, D. J.; Proudfoot, N. J. (1983). "α-Thalassaemia caused by a polyadenylation signal mutation". Nature. 306 (5941): 398–400. doi:10.1038/306398a0
HEMGN (526 words) [view diff] exact match in snippet view article find links to article
Yang LV, Heng HH, Wan J, et al. (2004). "Alternative promoters and polyadenylation regulate tissue-specific expression of Hemogen isoforms during hematopoiesis
Cordycepin (390 words) [view diff] exact match in snippet view article find links to article
A, Parker HN, Khurshid A, Tessier S, et al. (2012). "Inhibition of polyadenylation reduces inflammatory gene induction". RNA. 18 (12): 2236–50. doi:10
Exosome component 5 (723 words) [view diff] exact match in snippet view article find links to article
exonucleolytic catabolism of deadenylated mRNA • U4 snRNA 3'-end processing • polyadenylation-dependent snoRNA 3'-end processing • RNA catabolic process • rRNA processing
Cyclin-dependent kinase 4 (2,362 words) [view diff] exact match in snippet view article find links to article
are being tested for cancer treatment in clinical trials. Multiple polyadenylation sites of this gene have been reported. It is regulated by Cyclin D
GlmZ RNA (464 words) [view diff] exact match in snippet view article find links to article
the activation of glmS expression and is subject to regulation by polyadenylation in Escherichia coli". Nucleic Acids Res. 36 (8): 2570–2580. doi:10
Stearoyl-CoA desaturase-1 (2,841 words) [view diff] exact match in snippet view article find links to article
alternative transcripts generated from a single gene by usage of tandem polyadenylation sites". The Biochemical Journal. 340 (Pt 1): 255–64. doi:10.1042/bj3400255
GlmY RNA (435 words) [view diff] exact match in snippet view article find links to article
the activation of glmS expression and is subject to regulation by polyadenylation in Escherichia coli". Nucleic Acids Res. 36 (8): 2570–2580. doi:10
Laminin (3,269 words) [view diff] exact match in snippet view article find links to article
mRNA species arising from alternative transcription start sites or polyadenylation signals were detected that account for its translational control. Mapping
PRKAR1A (1,833 words) [view diff] exact match in snippet view article find links to article
cAMP-dependent protein kinase from human testis are due to the use of different polyadenylation site signals". Biochem. Biophys. Res. Commun. 167 (1): 323–30. doi:10
CCL7 (2,494 words) [view diff] exact match in snippet view article find links to article
3′-UTR containing one or more destabilizing AU-rich sequences and a polyadenylation signal. CCL7 was first characterized from osteosarcoma supernatant
GYPE (635 words) [view diff] exact match in snippet view article find links to article
common erythroid-specific promoter and alternative usage of different polyadenylation signals" (PDF). J. Biochem. 116 (1): 183–92. doi:10.1093/oxfordjournals
PREB (428 words) [view diff] exact match in snippet view article find links to article
2003). "The gene structure and expression of human ABHD1: overlapping polyadenylation signal sequence with Sec12". BMC Genomics. 4 (1): 18. doi:10.1186/1471-2164-4-18
Exosome component 6 (500 words) [view diff] exact match in snippet view article find links to article
exonucleolytic catabolism of deadenylated mRNA • U4 snRNA 3'-end processing • polyadenylation-dependent snoRNA 3'-end processing • rRNA processing • positive regulation
ARHGEF4 (773 words) [view diff] exact match in snippet view article find links to article
different isoforms. Also, there is possibility for the usage of multiple polyadenylation sites for this gene. Model organisms have been used in the study of
Excitatory amino acid transporter 2 (2,247 words) [view diff] exact match in snippet view article find links to article
Stamm S, Ludolph A, Meyer T (2000). "Differential RNA cleavage and polyadenylation of the glutamate transporter EAAT2 in the human brain". Brain Res.
ASAHL (518 words) [view diff] exact match in snippet view article find links to article
DL (Dec 1992). "A human endogenous long terminal repeat provides a polyadenylation signal to a novel, alternatively spliced transcript in normal placenta"
HMOX2 (1,003 words) [view diff] exact match in snippet view article find links to article
evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal". Arch Biochem Biophys. 295 (1): 13–20. doi:10.1016/0003-9861(92)90481-B
RNF40 (564 words) [view diff] exact match in snippet view article find links to article
protein-containing complex Biological process • negative regulation of mRNA polyadenylation • histone H2B ubiquitination • positive regulation of proteasomal protein
Cloning vector (2,572 words) [view diff] exact match in snippet view article find links to article
called transcription vectors. They may lack the sequences necessary for polyadenylation and termination, therefore may not be used for protein production.
Cyclin T1 (1,335 words) [view diff] exact match in snippet view article find links to article
protein serine/threonine kinase activity • negative regulation of mRNA polyadenylation • regulation of transcription, DNA-templated • transcription elongation
RET proto-oncogene (2,252 words) [view diff] exact match in snippet view article find links to article
"Characterization of RET proto-oncogene 3' splicing variants and polyadenylation sites: a novel C-terminus for RET". Oncogene. 11 (10): 2039–2045. PMID 7478523
SEC22B (733 words) [view diff] exact match in snippet view article find links to article
Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript. SEC22B has been shown to interact with syntaxin
GYPB (3,578 words) [view diff] exact match in snippet view article find links to article
common erythroid-specific promoter and alternative usage of different polyadenylation signals". J. Biochem. 116 (1): 183–92. doi:10.1093/oxfordjournals.jbchem
TIMP3 (977 words) [view diff] exact match in snippet view article find links to article
metalloproteinases-3 gene in breast carcinoma: identification of multiple polyadenylation sites and a stromal pattern of expression". Mol. Med. 1 (4): 418–27
CTR9 (771 words) [view diff] exact match in snippet view article find links to article
receptor signaling pathway via JAK-STAT • negative regulation of mRNA polyadenylation • regulation of transcription, DNA-templated • histone H3-K4 trimethylation
Exosome component 4 (747 words) [view diff] exact match in snippet view article find links to article
response to virus • rRNA 3'-end processing • rRNA catabolic process • polyadenylation-dependent snoRNA 3'-end processing • U4 snRNA 3'-end processing • nuclear-transcribed
PPIL3 (650 words) [view diff] exact match in snippet view article find links to article
Transcript variants derived from alternative splicing and/or alternative polyadenylation exist; some of these variants encode different isoforms. Model organisms
Cathepsin G (2,811 words) [view diff] exact match in snippet view article find links to article
property for serine proteases. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Cathepsin G was also found to exert broad-spectrum
Interferon-alpha/beta receptor (2,615 words) [view diff] exact match in snippet view article find links to article
isoforms due to alternative splicing, exon skipping, and multiple polyadenylation sites; IFNAR2a (a soluble form lacking the TM domain), IFNAR2b (a soluble
U4 spliceosomal RNA (1,664 words) [view diff] exact match in snippet view article find links to article
nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation". Cell. 46 (5): 691–6. doi:10.1016/0092-8674(86)90344-2. PMID 2427201
Receptor tyrosine kinase (3,069 words) [view diff] exact match in snippet view article find links to article
"Characterization of RET proto-oncogene 3' splicing variants and polyadenylation sites: a novel C-terminus for RET". Oncogene. 11 (10): 2039–45. PMID 7478523
RTN3 (933 words) [view diff] exact match in snippet view article find links to article
transcripts from the novel human apoptosis-inducing gene hap by alternative polyadenylation utilization and the translational activation function of 3' untranslated
RTF1 (778 words) [view diff] exact match in snippet view article find links to article
"Direct Interactions between the Paf1 Complex and a Cleavage and Polyadenylation Factor Are Revealed by Dissociation of Paf1 from RNA Polymerase II"
Structure and genome of HIV (3,731 words) [view diff] exact match in snippet view article find links to article
(5' to 3') include the trans-activation region (TAR) element, the 5' polyadenylation signal [poly(A)], the PBS, the DIS, the major SD and the ψ hairpin
PIP5K1A (661 words) [view diff] exact match in snippet view article find links to article
4-kinase activity Cellular component • nuclear speck • mRNA cleavage and polyadenylation specificity factor complex • cell projection • membrane • focal adhesion
ZFP36 (1,051 words) [view diff] exact match in snippet view article find links to article
"Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site". J. Biol. Chem
Collagen, type III, alpha 1 (3,414 words) [view diff] exact match in snippet view article find links to article
COL5A2. Two transcripts are generated from the gene using different polyadenylation sites. Although alternatively spliced transcripts have been detected
MRNA surveillance (3,389 words) [view diff] exact match in snippet view article find links to article
many different mechanisms such as premature 3' adenylation or cryptic polyadenylation signals within the coding region of a gene. This lack of a stop codon
FHL5 (956 words) [view diff] exact match in snippet view article find links to article
differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. FHL5 has been shown to interact with CREB1
Casein kinase 1, alpha 1 (340 words) [view diff] exact match in snippet view article find links to article
component • cytoplasm • centrosome • nuclear speck • mRNA cleavage and polyadenylation specificity factor complex • membrane • keratin filament • chromosome
Bocaparvovirus (1,223 words) [view diff] exact match in snippet view article find links to article
replication and is also required for the read through of an internal polyadenylation site that is essential for expression of the capsid proteins. Viral
Complement receptor 1 (2,865 words) [view diff] exact match in snippet view article find links to article
Atkinson JP, Holers VM (October 1988). "Identification of an alternative polyadenylation site in the human C3b/C4b receptor (complement receptor type 1) transcriptional
AU-rich element (1,070 words) [view diff] exact match in snippet view article find links to article
Protein HuR Autoregulates Its Expression by Promoting Alternative Polyadenylation Site Usage". Nucleic Acids Research. 40 (2): 787–800. doi:10.1093/nar/gkr783
Amylin (3,740 words) [view diff] exact match in snippet view article find links to article
amyloid polypeptide/amylin gene transcripts: identification of a new polyadenylation site". Biochem. Biophys. Res. Commun. 189 (3): 1569–77. doi:10
RANGAP1 (1,409 words) [view diff] exact match in snippet view article find links to article
Ponstingl H (1997). "Ubiquitous expression and testis-specific alternative polyadenylation of mRNA for the human Ran GTPase activator RanGAP1". Gene. 180 (1–2):
UPF1 (1,399 words) [view diff] exact match in snippet view article find links to article
homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. UPF1 has been shown to interact
UniGene (1,263 words) [view diff] exact match in snippet view article find links to article
all clusters are ‘‘anchored,’’ and contain either a sequence with a polyadenylation site or two ESTs labeled as coming from the 3 end of a clone. Clone-based
Astrovirus (4,735 words) [view diff] exact match in snippet view article find links to article
a poly A tail at the 3' end, but no 5' cap. With the exclusion of polyadenylation at the 3' end, the genome is between 6.8–7.9 kb long. The genome is
CDC73 (1,241 words) [view diff] exact match in snippet view article find links to article
mitotic cell cycle • positive regulation of Wnt signaling pathway • mRNA polyadenylation • endodermal cell fate commitment • protein destabilization • negative
Serial analysis of gene expression (2,122 words) [view diff] exact match in snippet view article find links to article
breeding. In addition, the approach allows determining alternative polyadenylation of the transcripts. Because MACE does only require 3’ ends of transcripts
FLOT1 (1,170 words) [view diff] exact match in snippet view article find links to article
cDNA cloning from human lung and the identification of alternative polyadenylation signals". Int. J. Biochem. Cell Biol. 33 (1): 53–64. doi:10
RNF20 (861 words) [view diff] exact match in snippet view article find links to article
regulation of transcription, DNA-templated • negative regulation of mRNA polyadenylation • positive regulation of histone methylation • ubiquitin-dependent
Trifunctional purine biosynthetic protein adenosine-3 (959 words) [view diff] exact match in snippet view article find links to article
1093/hmg/6.12.2043. PMID 9328467. Kan JL, Moran RG (1997). "Intronic polyadenylation in the human glycinamide ribonucleotide formyltransferase gene". Nucleic
Serotonin transporter (3,543 words) [view diff] exact match in snippet view article find links to article
Balling U, Riederer P, Lesch KP (1995). "Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene". Journal
RDBP (1,192 words) [view diff] exact match in snippet view article find links to article
of transcription by RNA polymerase II • negative regulation of mRNA polyadenylation • transcription elongation from RNA polymerase II promoter • transcription
Minute virus of mice (987 words) [view diff] exact match in snippet view article find links to article
transcriptional promoters at map units (mu) 4 and 38 (p4 and p38) and a single polyadenylation site at mu 95 to create 3 major size classes of mRNAs, referred to
IPO5 (1,195 words) [view diff] exact match in snippet view article find links to article
translocation through the pore complex. IPO5 facilitates cytoplasmic polyadenylation element-binding protein (CPEB)3 translocation by binding to RRM1 motif
Trans-regulatory element (1,295 words) [view diff] exact match in snippet view article find links to article
post-transcriptional regulation, which mostly happens in eukaryotes. 3′ cleavage/polyadenylation and 5’ capping increase overall RNA stability, and the presence of
Catherine Hartley (2,151 words) [view diff] exact match in snippet view article find links to article
Holmes A, Casey BJ, Phelps EA, Glatt CE. 2012. Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory. Proceedings
Knockout rat (3,265 words) [view diff] exact match in snippet view article find links to article
frames (ORFs), and a 3’ untranslated region containing sequences for polyadenylation. The two ORFs encode proteins necessary for autonomous retrotransposition;
CORO6 (858 words) [view diff] exact match in snippet view article find links to article
There are 3 probable alternative promoters, and validated alternative polyadenylation sites. CORO6 protein sequence contains WD-40 repeats. WD40 domain is
JADE1 (5,937 words) [view diff] exact match in snippet view article find links to article
transcripts in both humans and mice undergo alternative splicing and polyadenylation producing two major transcripts, the full length 6 kb mRNA and 3.6
SUPT5H (1,532 words) [view diff] exact match in snippet view article find links to article
Biological process • chromatin remodeling • negative regulation of mRNA polyadenylation • regulation of transcription, DNA-templated • regulation of transcription
Apolipoprotein B (4,641 words) [view diff] exact match in snippet view article find links to article
event that occurs posttranscriptionally coincident with splicing and polyadenylation". J. Biol. Chem. 266 (30): 20550–20554. doi:10.1016/S0021-9258(18)54960-7
Human bocavirus (2,970 words) [view diff] exact match in snippet view article find links to article
This is responsible for, by alternative splicing and alternative polyadenylation, for the generation of several (at least 6) mRNAs. The poly A tail
Human bocavirus (2,970 words) [view diff] exact match in snippet view article find links to article
This is responsible for, by alternative splicing and alternative polyadenylation, for the generation of several (at least 6) mRNAs. The poly A tail
RNA-binding protein database (1,371 words) [view diff] exact match in snippet view article find links to article
post-transcriptional modification which includes splicing, editing and polyadenylation to process the pre-mRNA. RNA-binding proteins ( RBPs ) play critical
THOC5 (1,473 words) [view diff] exact match in snippet view article find links to article
K, Ohkawa Y (2013) Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I. Nucleic Acids
Non-POU domain-containing octamer-binding protein (2,492 words) [view diff] exact match in snippet view article find links to article
M, Hentze MW, Kulozik AE (June 2007). "Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals". The EMBO Journal
Amyloid-beta precursor protein (5,431 words) [view diff] exact match in snippet view article find links to article
cycle • axo-dendritic transport • response to oxidative stress • mRNA polyadenylation • collateral sprouting in absence of injury • ionotropic glutamate
CYB5R3 (2,017 words) [view diff] exact match in snippet view article find links to article
average GC of the entire gene, which is 55%. There is also an atypical polyadenylation signal in the 3'-untranslated region of the gene. The protein encoded
Hemoglobin, alpha 2 (1,373 words) [view diff] exact match in snippet view article find links to article
(Apr 2010). "alpha-thalassaemia masked by beta gene defects and a new polyadenylation site mutation on the alpha2-globin gene". European Journal of Haematology
KIAA1211L (1,314 words) [view diff] exact match in snippet view article find links to article
by green boxes, the stop codon is red, the predicted miRNA 132 target is underlined in purple, and the polyadenylation signal is highlighted magenta.
Let-7 microRNA precursor (8,116 words) [view diff] exact match in snippet view article find links to article
Hunter S, Eachus R, Weeks P, Pasquinelli AE (2004). "Trans-splicing and polyadenylation of let-7 microRNA primary transcripts". RNA. 10 (10): 1586–94. doi:10
5-HTTLPR (4,328 words) [view diff] exact match in snippet view article find links to article
Balling U, Riederer P, Lesch KP (1995). "Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene". Journal
N6-Methyladenosine (5,208 words) [view diff] exact match in snippet view article find links to article
(>=70%) allows the potential for 3'UTR regulation, including alternative polyadenylation. The study combining m6A-CLIP with rigorous cell fractionation biochemistry
Leucine-rich repeats and iq motif containing 1 (846 words) [view diff] exact match in snippet view article find links to article
produces 10 different mRNAs. LRRIQ1 has two validated alternative polyadenylation sites. The most common isoform consists of 5,460 base pairs in length
U7 small nuclear RNA (3,621 words) [view diff] exact match in snippet view article find links to article
PMID 2141911. S2CID 1650768. Kirsh AL, Groudine M, Challoner PB (1989). "Polyadenylation and U7 snRNP-mediated cleavage: alternative modes of RNA 3' processing
INAVA (1,514 words) [view diff] exact match in snippet view article find links to article
shorter due to a truncated N-terminus. Both isoforms have an alternative polyadenylation site. miRNA-24 was identified as a microRNA that could potentially
HIV integration (2,122 words) [view diff] exact match in snippet view article find links to article
Fadel HJ, Poeschla EM, et al. (2016). "A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active
BRCA1 (14,067 words) [view diff] exact match in snippet view article find links to article
(September 1999). "Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50". Science. 285 (5433): 1576–9. doi:10.1126/science.285
APOA5 (4,988 words) [view diff] exact match in snippet view article find links to article
11q23 and contains 4 exons and 3 introns. This gene uses alternate polyadenylation sites and is located proximal to the apolipoprotein gene cluster on
Cryptic unstable transcript (2,288 words) [view diff] exact match in snippet view article find links to article
complex (a collective complex referred to as TRAMP: Trf-Air-Mtr4 Polyadenylation complex) which serves as an alternative Poly(A) polymerase to Pap1p
Suzanne Zukin (1,425 words) [view diff] exact match in snippet view article find links to article
Control of mRNA Translation and Synaptic Plasticity by the Cytoplasmic Polyadenylation Complex". Molecular Cell. 47 (2): 253–266. doi:10.1016/j.molcel.2012
FAM71E2 (1,192 words) [view diff] exact match in snippet view article find links to article
transcription: aAUG10 and bAUG10. They are both validated alternative polyadenylation sites. However, there are no isoforms of FAM71E2. Conserved stem loop
Reelin (15,611 words) [view diff] exact match in snippet view article find links to article
impact of this is unknown. Two transcription initiation sites and two polyadenylation sites are identified in the gene structure. The reelin protein starts
Feline morbillivirus (1,590 words) [view diff] exact match in snippet view article find links to article
transcription of the genome into mRNA, as well as sequential capping and polyadenylation of the mRNA. Before replication starts, enough nucleoprotein must be
MAP11 (1,907 words) [view diff] exact match in snippet view article find links to article
1 encodes a protein that is 580 amino acids long and only has one polyadenylation site. C7orf43 isoform 2 is 2085 base pairs long and encodes a protein
Jack D. Keene (1,882 words) [view diff] exact match in snippet view article find links to article
proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation". Nucleic Acids Research. 40 (6): 2734–2746. doi:10.1093/nar/gkr1114
GOLGA8H (1,354 words) [view diff] exact match in snippet view article find links to article
cells. The protein is 632 amino acids long. It has 19 exons and two polyadenylation signals. Its sequence only partially matches a Kozak consensus sequence
C15orf54 (1,139 words) [view diff] exact match in snippet view article find links to article
3' UTR contains 2160 bp followed by the polyA. The standard AATAAA polyadenylation signal is seen about 23 bp before the polyA. The predicted protein
PURA (4,033 words) [view diff] exact match in snippet view article find links to article
contrapodal to WRN on chromosome 8, determined by differential termination/polyadenylation". Nucleic Acids Research. 30 (11): 2417–26. doi:10.1093/nar/30.11.2417
G&T-Seq (2,618 words) [view diff] exact match in snippet view article find links to article
but do not present the standard polyA tail length due to alternative polyadenylation. Therefore, G&Ts comparison of genotype–phenotype correlation does
RBM10 (5,513 words) [view diff] exact match in snippet view article find links to article
regulation, RBM10 participates in other reactions. Some examples are polyadenylation of cardiac pre-mRNAs of anti-hypertrophy regulators, wherein it acts
Kári Stefánsson (12,357 words) [view diff] exact match in snippet view article find links to article
18 January 2009; SN Stacey et al., "A germline variant in the TP53 polyadenylation signal confers cancer susceptibility," Nature Genetics, 43(11):1098-103
CUX1 (4,649 words) [view diff] exact match in snippet view article find links to article
alternative first exons and an additional 23 exons. The last exon has a weak polyadenylation site allowing RNA polymerase II often to continue transcribing until
ISLR (4,077 words) [view diff] exact match in snippet view article find links to article
912 bp (Figure 5) extracted from Genomatix. Additionally, there is a polyadenylation signal at 3,142 bp in the ISLR nucleotide sequence (humans). There
List of RNA-Seq bioinformatics tools (18,706 words) [view diff] exact match in snippet view article find links to article
can detect differential RNA processing (e.g. alternative splicing, polyadenylation or ribosome occupancy). RNASeqPower Calculating samples Size estimates