funding. Perlecan Pharma was partially funded by ICICI Venture Capital and Citigroup Venture International, both of which held a 43% stake in Perlecan for
leucine-rich repeats (LRRs), seven to nine EGF repeats, an ALPS domain (Agrin, Perlecan, Laminin, Slit), and a cysteine knot. Robos are characterized by five Ig-like
alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan". FEBS Lett. 430 (3): 217–21. doi:10.1016/S0014-5793(98)00601-2. PMID 9688542
suprastructure containing laminins (laminin-5), entactin/nidogen or the perlecan on the extracellular surface of the hemidesmosome, laminin-5 molecules
suprastructure containing laminins (laminin-5), entactin/nidogen or the perlecan on the extracellular surface of the hemidesmosome, laminin-5 molecules
ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin". J. Biol. Chem. 277 (25): 23092–9. doi:10.1074/jbc.M107583200
ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin". The Journal of Biological Chemistry. 277 (25): 23092–9.
ColVI allows muscle cells to connect with the ECM by interacting with perlecan in the basal lamina. ColVI also functions as a cytoprotective agent: ColVI
include fibulin-1, fibronectin, entactin, and heparin sulfate proteoglycan perlecan. Ultimately, the astrocytes attach to the basal membrane, and the complex
Underwood PA (April 1996). "The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase
organs in Drosophila by opposing roles of fat body-secreted Collagen IV and perlecan". Developmental Cell. 21 (2): 245–56. doi:10.1016/j.devcel.2011.06.026