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searching for Oxidative deamination 49 found (79 total)

Hydroxypyruvic acid (104 words) [view diff] exact match in snippet view article find links to article

lactic acid, a degradation product of RuBisCO, and the result of oxidative deamination of serine. Hydroxypyruvate reductase Hydroxypyruvate isomerase Hydroxypyruvate

Protein catabolism (963 words) [view diff] exact match in snippet view article find links to article

(ubiquitylation) marks a protein for degradation via the proteasome. Oxidative deamination is the first step to breaking down the amino acids so that they

5-Hydroxyuracil (111 words) [view diff] exact match in snippet view article find links to article

5-Hydroxyuracil is an oxidized form of cytosine that is produced by the oxidative deamination of cytosines by reactive oxygen species. It does not distort the

DDO (gene) (508 words) [view diff] exact match in snippet view article

encoded by this gene is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide

Glutamate dehydrogenase (1,654 words) [view diff] exact match in snippet view article find links to article

the brain, the NAD+/NADH ratio in brain mitochondria encourages oxidative deamination (i.e. glutamate to α-ketoglutarate and ammonia). In bacteria, the

5-Hydroxyindoleacetaldehyde (621 words) [view diff] exact match in snippet view article find links to article

(5-hydroxytryptamine; 5-HT). 5-HIAL is formed from serotonin by oxidative deamination via monoamine oxidase (MAO). MAO-mediated deamination is the primary

Monoamine oxidase A (4,637 words) [view diff] exact match in snippet view article find links to article

family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. A mutation

Mary Bernheim (1,288 words) [view diff] exact match in snippet view article find links to article

Bernheim predicted that tyramine oxidase was important for the oxidative deamination of tyramine, thus allowing for the detoxification of extra amines

Saccharopine dehydrogenase (438 words) [view diff] exact match in snippet view article find links to article

oxidant to catalyse the reversible pyridine nucleotide dependent oxidative deamination of the substrate, Saccharopine, in order to form the products, lysine

Amicyanin (264 words) [view diff] exact match in snippet view article find links to article

electron-accepting intermediate. In this reaction, MADH catalyzes the oxidative deamination of methylamine to formaldehyde plus ammonia. The tryptophan tryptophylquinone

Isobutyraldehyde (362 words) [view diff] exact match in snippet view article find links to article

modified to produce isobutanol. α-Ketoisovalerate, derived from oxidative deamination of valine, is prone to decarboxylation to give isobutyraldehyde

Sulfation (1,082 words) [view diff] exact match in snippet view article find links to article

Hydroxylation Ubiquitination Sumoylation ADP-ribosylation Deamination Oxidative deamination to aldehyde O-glycosylation Imine formation Glycation Carbamylation

GLUD2 (936 words) [view diff] exact match in snippet view article find links to article

neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. ENSG00000288118 GRCh38: Ensembl

3,4-Dihydroxyphenylglycolaldehyde (360 words) [view diff] exact match in snippet view article find links to article

noradrenergic neurotoxin. DOPEGAL is formed by monoamine oxidase (MAO) via oxidative deamination. Following its formation, DOPEGAL is metabolized. Through the metabolism

Glutamate dehydrogenase 1 (3,043 words) [view diff] exact match in snippet view article find links to article

NAD+, or NADH, but does not bind NADPH well. GLUD1 catalyses the oxidative deamination of Glu to 2-oxoglutarate and free NH4+ using either NAD+ or NADP+

Benzylisoquinoline alkaloids (384 words) [view diff] exact match in snippet view article find links to article

hydroxylation and decarboxylation and to 4-hydroxyphenylacetaldehyde by oxidative deamination, respectively. These two compounds are converted into dopamine by

4-Hydroxyphenylacetone (1,191 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

P-Hydroxynorephedrine (1,230 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

Nanoarchaeum equitans (993 words) [view diff] exact match in snippet view article find links to article

does have five subunits of an ATP synthase as well as pathways for oxidative deamination. Whether it obtains energy from biological molecules imported from

Aldehyde (3,092 words) [view diff] exact match in snippet view article find links to article

of nucleophiles to the formyl carbon in the formation of imines (oxidative deamination) and hemiacetals (structures of aldose sugars). Because of resonance

Aspartate transaminase (2,115 words) [view diff] exact match in snippet view article find links to article

α-ketoglutarate to glutamate, glutamate subsequently undergoes oxidative deamination to form ammonium ions, which are excreted as urea. In the reverse

4-Methylthioamphetamine (1,888 words) [view diff] exact match in snippet view article find links to article

(step I). Ring hydroxylation to a phenolic structure (step II). Oxidative deamination to form an oxo metabolite, followed by (step III): reduction into

Cinnamaldehyde (1,852 words) [view diff] exact match in snippet view article find links to article

phenylalanine ammonia lyase (PAL). PAL catalyzes this reaction by a non-oxidative deamination. This deamination relies on the MIO prosthetic group of PAL. PAL

Phenylpropanolamine (5,576 words) [view diff] exact match in snippet view article find links to article

dose of PPA is metabolized. Metabolites include hippuric acid (via oxidative deamination of the side chain) and 4-hydroxynorephedrine (via para-hydroxylation)

Pyridoxal phosphate (2,937 words) [view diff] exact match in snippet view article find links to article

seizures in children. Pyridoxal phosphate also participates in the oxidative deamination of GABA, where it is a cofactor of GABA aminotransferase. Metabolism

4-Hydroxyamphetamine (2,283 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

Levoamphetamine (6,394 words) [view diff] exact match in snippet view article find links to article

hydroxylation to produce 4-hydroxyamphetamine and additionally via oxidative deamination. There are several enzymes involved in the metabolism of amphetamine

DNA demethylation (5,158 words) [view diff] exact match in snippet view article find links to article

is followed by base excision repair (stage 3). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by APOBEC (AID/APOBEC)

Reprogramming (5,387 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by APOBEC (AID/APOBEC)

DNA demethylation (5,158 words) [view diff] exact match in snippet view article find links to article

is followed by base excision repair (stage 3). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by APOBEC (AID/APOBEC)

Base excision repair (3,493 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by activity-induced

Amitraz (3,737 words) [view diff] exact match in snippet view article find links to article

effect of amitraz has been found. Monoamine oxidases catalyze the oxidative deamination of monoamines and thereby form flavoproteins and inactivate neurotransmitters

Angelicin (3,002 words) [view diff] exact match in snippet view article find links to article

L-phenylalanine as a precursor. The phenylalanine undergoes a non-oxidative deamination by phenylalanine ammonia-lyase (PAL) to trans-cinnamic acid. Afterwards

8-Oxo-2'-deoxyguanosine (2,763 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by activity-induced

CpG site (5,479 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by activity-induced

Hypersensitive response (3,840 words) [view diff] exact match in snippet view article find links to article

generation of ROS. For example, copper amine oxidase, catalyzes the oxidative deamination of polyamines, especially putrescine, and releases the ROS mediators

Lysine (7,547 words) [view diff] exact match in snippet view article find links to article

involves the saccharopine dehydrogenase (SDH) (E.C 1.5.1.8) catalysed oxidative deamination of saccharopine, resulting in L-lysine. In a variant AAA pathway

DNA oxidation (4,790 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by activity-induced

DNA-3-methyladenine glycosylase (2,620 words) [view diff] exact match in snippet view article find links to article

subject to a large number of anomalies: spontaneous alkylation or oxidative deamination. It is estimated that 104 mutations appear in a typical human cell

Βk-2C-B (2,930 words) [view diff] exact match in snippet view article find links to article

liver hepatocytes, resulting in deamination and demethylation. Oxidative deamination is common, and substitutes of dimethoxybenzoic acid can be produced

Reactive oxygen species (8,490 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by activity-induced

Lisdexamfetamine (14,062 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

Cocaine (19,615 words) [view diff] exact match in snippet view article find links to article

putrescine gives the N-methylputrescine product, which then undergoes oxidative deamination by the action of diamine oxidase to yield the aminoaldehyde. Schiff

Management of thalassemia (4,881 words) [view diff] exact match in snippet view article find links to article

lysyl oxidase, which uses copper as a cofactor and catalyzes the oxidative deamination step that is important for cross-linking of collagen, cannot function

Adderall (21,870 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

Epigenetics in learning and memory (6,235 words) [view diff] exact match in snippet view article find links to article

resulting in an apyrimidinic site (AP site). In an alternative oxidative deamination pathway, 5hmC can be oxidatively deaminated by activity-induced

Amphetamine (28,887 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

Dextroamphetamine (20,955 words) [view diff] case mismatch in snippet view article find links to article

CYP2D6 unidentified Beta- Hydroxylation Beta- Hydroxylation DBH DBH Oxidative Deamination FMO3 Oxidation unidentified Glycine Conjugation XM-ligase GLYAT

6-Formylindolo(3,2-b)carbazole (4,634 words) [view diff] exact match in snippet view article

have been identified to convert Trp to FICZ via the precursor I3A. Oxidative deamination of Trp by aromatic amino acid aminotransferases (ArAT) or L-amino