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searching for Nav1.2 23 found (46 total)

alternate case: nav1.2

Protoxin-I (1,797 words) [view diff] case mismatch in snippet view article find links to article

D31A, G31A, F34A reduce the toxin's ability to inhibit sodium channels NaV1.2.  Similarly, the replacements L6A, L19A, W27A, V29A, W30A, D31A also reduce
Edgar Pons (211 words) [view diff] no match in snippet view article find links to article
4 5 6 7 8 9 10 11 Pos Pts 2014 Tech3 JER 1 ARA1 5 ARA2 DNF CAT 7 ALB 6 NAV1 2 NAV2 6 ALG1 3 ALG2 1 VAL 3 3rd 142 2015 Kalex ALG1 1 ALG2 2 CAT 1 ARA1 1
Ambroxol (1,288 words) [view diff] exact match in snippet view article find links to article
analgesics on TTX-resistant Na+ currents in rat sensory neurons and recombinant Nav1.2 channels". Neuroscience Letters. 395 (3): 179–84. doi:10.1016/j.neulet.2005
Alan Techer (164 words) [view diff] no match in snippet view article find links to article
ALG2 3 VAL Ret 6th 79 2015 Tech3 ALG1 6 ALG2 5 CAT 3 ARA1 7 ARA2 6 ALB 5 NAV1 2 NAV2 5 JER 5 VAL1 5 VAL2 4 3rd 133 2016 NTS VAL1 3 VAL2 2 ARA1 3 ARA2 2
Ankyrin-3 (1,651 words) [view diff] exact match in snippet view article find links to article
C, et al. (2004). "Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin
PhTx-1 (121 words) [view diff] exact match in snippet view article find links to article
known as Tx1, exerts an inhibitory effect on neuronal sodium channels (Nav1.2). This component is considered highly pathogenic for primates. Resende,
Phrixotoxin (692 words) [view diff] exact match in snippet view article find links to article
(PaurTx3) inhibits several voltage gated sodium channel subtypes (Nav1.1/SCN1A, Nav1.2/SCN2A, Nav1.4/SCN4A, Nav1.5/SCN5A, and Nav1.8/SCN10A) (Bosmans 2006) harv
Alexander Smolyar (873 words) [view diff] no match in snippet view article find links to article
18 19 20 Pos Points 2017 SMP Racing ALC 1 2 ALC 2 Ret ALC 3 11 NAV1 1 1 NAV1 2 3 NAV1 3 10 CAT 1 3 CAT 2 1 JER 1 1 JER 2 1 JER 3 1 NAV2 1 DSQ NAV2 2 DSQ
Dendritic spike (2,986 words) [view diff] exact match in snippet view article find links to article
been well documented in the axonal membrane of the central nervous system. Nav1.2 has been primarily identified in unmyelinated axons while high concentrations
Marta García (racing driver) (1,117 words) [view diff] no match in snippet view article
2 7 JER 3 5 NC† 0 2017 MP Motorsport ALC 1 10 ALC 2 6 ALC 3 6 NAV1 1 9 NAV1 2 12 NAV1 3 7 CAT 1 8 CAT 2 9 JER 1 6 JER 2 5 JER 3 13† NAV2 1 7 NAV2 2 10
Lukas Dunner (346 words) [view diff] no match in snippet view article find links to article
19 20 Pos Points 2017 MP Motorsport ALC 1 7 ALC 2 Ret ALC 3 4 NAV1 1 4 NAV1 2 5 NAV1 3 Ret CAT 1 11 CAT 2 6 JER 1 11 JER 2 8 JER 3 6 NAV2 1 3 NAV2 2 4
Bent Viscaal (1,415 words) [view diff] no match in snippet view article find links to article
19 20 Pos Points 2017 MP Motorsport ALC 1 Ret ALC 2 3 ALC 3 8 NAV1 1 6 NAV1 2 2 NAV1 3 1 CAT 1 1 CAT 2 2 JER 1 7 JER 2 7 JER 3 4 NAV2 1 2 NAV2 2 3 NAV2
Dextromethorphan (4,585 words) [view diff] exact match in snippet view article find links to article
He YL, Hu C, Mei YA (2012). "Sigma-1 receptor agonists directly inhibit Nav1.2/1.4 channels". PLOS ONE. 7 (11): e49384. Bibcode:2012PLoSO...749384G. doi:10
Neosaxitoxin (5,241 words) [view diff] exact match in snippet view article find links to article
fashion to VGSCs. In fact, when Phe 385 near the selectivity filter of Nav1.2 is mutated to Cys, the channel's affinity for TTX is reduced 3,000-fold
Cl6a (1,052 words) [view diff] case mismatch in snippet view article find links to article
antagonist of voltage-gated sodium channels. It targets TTX-S channels (NaV1.2, NaV1.3, NaV1.4, NaV1.6 and NaV1.7) with the highest affinity against NaV1
Dravet syndrome (4,117 words) [view diff] exact match in snippet view article find links to article
SCN2A: This gene encodes the alpha-2 subunit of the sodium ion channel (Nav1.2). The expression of this gene increases throughout childhood (unlike SCN1A
Amitriptyline (8,657 words) [view diff] exact match in snippet view article find links to article
7, and Nav1.8 neuronal voltage-gated sodium channels more potently than Nav1.2 and Nav1.6 channels expressed in Xenopus oocytes". Naunyn-Schmiedeberg's
Generalized epilepsy with febrile seizures plus (3,407 words) [view diff] exact match in snippet view article find links to article
Yamakawa K (2001). "A missense mutation of the Na+ channel αII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction"
Christian Lundgaard (7,561 words) [view diff] no match in snippet view article find links to article
18 19 20 Pos Points 2017 MP Motorsport ALC 1 1 ALC 2 1 ALC 3 1 NAV1 1 2 NAV1 2 1 NAV1 3 2 CAT 1 2 CAT 2 5 JER 1 3 JER 2 4 JER 3 3 NAV2 1 1 NAV2 2 2 NAV2
Nazim Azman (1,817 words) [view diff] no match in snippet view article find links to article
16 17 18 19 20 Pos Points 2017 MP Motorsport ALC 1 ALC 2 ALC 3 NAV1 1 5 NAV1 2 10 NAV1 3 5 CAT 1 9 CAT 2 11 JER 1 14 JER 2 11 JER 3 10 NAV2 1 8 NAV2 2
Epilepsy-intellectual disability in females (4,237 words) [view diff] exact match in snippet view article find links to article
(2001-05-22). "A missense mutation of the Na+ channel αII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction"
Stephen Waxman (4,692 words) [view diff] exact match in snippet view article find links to article
S.G. Molecular changes in neurons in MS: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+ /Ca2+ exchanger.  Proceedings of the
Developmental bioelectricity (17,264 words) [view diff] case mismatch in snippet view article find links to article
K+ channel Abnormalities of rectum, pancreas, and stomach Mus musculus NaV1.2 Muscle and nerve repair defects Xenopus Kir6.1 K+ channel Eye patterning