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searching for Metastasis suppressor 41 found (61 total)

NDRG1 (2,179 words) [view diff] exact match in snippet view article find links to article

Kovacevic et al., NDRG1 is a potent, iron-regulated growth and metastasis suppressor that was found to be negatively correlated with cancer progression

SDPR (726 words) [view diff] exact match in snippet view article find links to article

shown to act as a metastasis suppressor by xenograft studies utilizing breast cancer cell lines. SDPR may elicit its metastasis suppressor function by directly

Ceramide synthase 2 (840 words) [view diff] no match in snippet view article find links to article

synthase 2, also known as LAG1 longevity assurance homolog 2 or Tumor metastasis-suppressor gene 1 protein is an enzyme that in humans is encoded by the CERS2

Xiaohong Rose Yang (761 words) [view diff] case mismatch in snippet view article find links to article

Comprehensive Cancer Center in 1999. Her dissertation was titled KAI1, A Metastasis Suppressor Gene for Human Breast Cancer. Yang's mentors were Marc E. Lippman

NME2 (1,267 words) [view diff] no match in snippet view article find links to article

localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23-1 and NM23-2". Oncogene. 8 (2): 497–502. PMID 8381224

ARHGDIB (2,379 words) [view diff] exact match in snippet view article find links to article

metastasis in several tumor models. In contrast to its role as a metastasis suppressor in bladder cancer, in breast, RhoGDI2 expression has been reported

DRG1 (581 words) [view diff] exact match in snippet view article find links to article

S, Pai SK, Hirota S, et al. (2004). "Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression". Oncogene. 23 (33): 5675–81

RAR-related orphan receptor beta (1,061 words) [view diff] exact match in snippet view article find links to article

Paravicini G, Steinmayr M, André E, Becker-André M (October 1996). "The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts

Coenzyme A (2,528 words) [view diff] exact match in snippet view article find links to article

inhibition of the catalytic activity of different proteins (e.g. metastasis suppressor NME1, peroxiredoxin 5, GAPDH, among others) is reported. To restore

IGSF8 (601 words) [view diff] exact match in snippet view article find links to article

Lane WS, Charrin S, et al. (2003). "EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells".

RRAD (gene) (950 words) [view diff] exact match in snippet view article

Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation". Proc. Natl

GPR68 (555 words) [view diff] exact match in snippet view article find links to article

et al. (2007). "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer". J. Natl. Cancer Inst. 99 (17): 1313–27

MMP24 (620 words) [view diff] exact match in snippet view article find links to article

Takino T, Koshikawa N, Miyamori H, et al. (2003). "Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases"

MMP16 (982 words) [view diff] exact match in snippet view article find links to article

S2CID 21596144. Takino T, Koshikawa N, Miyamori H (2003). "Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases"

Lactococcus lactis (3,078 words) [view diff] exact match in snippet view article find links to article

PMC 3102199. PMID 20640864. Nash KT, Welch DR (2006). "The KISS1 metastasis suppressor: mechanistic insights and clinical utility". Frontiers in Bioscience

PTPRD (1,325 words) [view diff] exact match in snippet view article find links to article

Woodings JA, Sharp SJ, Machesky LM (April 2003). "MIM-B, a putative metastasis suppressor protein, binds to actin and to protein tyrosine phosphatase delta"

ARID4A (1,052 words) [view diff] exact match in snippet view article find links to article

JL, Eckert KA, Verderame MF, Welch DR (Jan 2004). "Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1

Intravasation (975 words) [view diff] exact match in snippet view article find links to article

enabling tumor cell invasion and intravasation. A newly identified metastasis suppressor, p75 neurotrophin receptor (p75NTR), is able to suppress metastasis

CNKSR1 (836 words) [view diff] exact match in snippet view article find links to article

Palmieri D, Ouatas T, Mair M, Patrick J, Steeg PS (2002). "Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein

Shantanu Chowdhury (1,096 words) [view diff] exact match in snippet view article find links to article

genomics. The group focuses its studies on the control of NME2, a metastasis suppressor, on telomerase function and the biological action of DNA secondary

RRM1 (988 words) [view diff] exact match in snippet view article find links to article

and contig of chromosome segment 11p15.5 and genes in the LOH11A metastasis suppressor region". Genomics. 55 (2): 164–75. doi:10.1006/geno.1998.5659. PMID 9933563

Leukemia inhibitory factor receptor (1,325 words) [view diff] exact match in snippet view article find links to article

glycoprotein 130. LIFR has also been identified as a breast cancer metastasis suppressor that functions through the Hippo-YAP pathway. LIFR is down regulated

DLC1 (3,165 words) [view diff] no match in snippet view article find links to article

migration. Furthermore, in breast cancer cells, DLC1 functions as a metastasis-suppressor gene by inhibiting colonization of a secondary tumor site. Expression

Nucleoside-diphosphate kinase (2,538 words) [view diff] exact match in snippet view article find links to article

group, one of the genes named NM23 was identified as the first metastasis suppressor protein and its gene Nm23 was less activated in metastatic cells

TRIM21 (1,478 words) [view diff] exact match in snippet view article find links to article

and contig of chromosome segment 11p15.5 and genes in the LOH11A metastasis suppressor region". Genomics. 55 (2): 164–75. doi:10.1006/geno.1998.5659. PMID 9933563

MSRA (gene) (1,219 words) [view diff] exact match in snippet view article

(2007). "Identification of MSRA gene on chromosome 8p as a candidate metastasis suppressor for human hepatitis B virus-positive hepatocellular carcinoma".

TCF21 (gene) (3,630 words) [view diff] no match in snippet view article

metastatic melanoma progression through the inhibition of the KISS1 metastasis-suppressor gene. DNA methylation analysis in melanoma patient biopsies has

GDI2 (928 words) [view diff] exact match in snippet view article find links to article

Sapinoso LM, Conaway MR, et al. (2004). "Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with

T-cell lymphoma invasion and metastasis-inducing protein 1 (1,315 words) [view diff] exact match in snippet view article find links to article

M, Yoshii S, Kawazoe N, Nakaya K, Sugimura H (Apr 2001). "Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1". Proceedings

Integrin beta 1 (2,600 words) [view diff] exact match in snippet view article find links to article

domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion

ITGB1BP1 (1,167 words) [view diff] exact match in snippet view article find links to article

domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion

Chordin-like 1 (1,006 words) [view diff] exact match in snippet view article find links to article

outcome is carcinogenic formation. Since CHRDL1 is a tumor and metastasis suppressor, a mutation in this gene may lead to tumor cell formation. The most

Baek Sung-hee (1,092 words) [view diff] exact match in snippet view article find links to article

Michael G.; Baek, Sung Hee (2005). "Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes". Nature. 434 (7035): 921–6

TOP1 (2,141 words) [view diff] no match in snippet view article find links to article

N-myc downstream regulated gene 1 (NDRG1) expression. NDRG1 is a metastasis-suppressor gene in prostate cancer, and appears to have a role in DNA repair

BHLHE41 (3,158 words) [view diff] exact match in snippet view article find links to article

metastasis of triple-negative-breast cancer (TNBC). Regulated by the p63 metastasis suppressor, BHLHE41 inhibits TNBC through the inhibition of HIF-1α and hypoxia-inducible

MEN1 (2,664 words) [view diff] exact match in snippet view article find links to article

exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23". The Journal of Biological Chemistry. 277 (41): 38197–204

Adapter molecule crk (2,941 words) [view diff] exact match in snippet view article find links to article

B, Liu L, Reddivari M, Zhang XA (2004). "The palmitoylation of metastasis suppressor KAI1/CD82 is important for its motility- and invasiveness-inhibitory

G-quadruplex (11,911 words) [view diff] exact match in snippet view article find links to article

also been identified as a key G-quadruplex resolvase. In 2009, a metastasis suppressor protein NM23H2 (also known as NME2) was found to directly interact

PBDC1 (2,603 words) [view diff] exact match in snippet view article find links to article

Yu SL, Che TF, Lin CW, et al. (January 2009). "Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma". Am

Duffy antigen system (9,574 words) [view diff] exact match in snippet view article find links to article

functioning is preserved in these individuals. Interactions between the metastasis suppressor KAI1 on tumor cells and the cytokine receptor DARC on adjacent vascular

FAM76A (2,200 words) [view diff] exact match in snippet view article find links to article

Wu YY, Lee YC, Hong TM, Yang PC (January 2009). "Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma". American