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Longer titles found: Subthreshold membrane potential oscillations (view)

searching for Membrane potential 355 found (773 total)

alternate case: membrane potential

JTV-519 (831 words) [view diff] exact match in snippet view article find links to article

leak, it is able to prevent Ca2+ sparks or increases in the resting membrane potential, which can lead to spontaneous depolarization (cardiac arrhythmias)
UCP2 (1,158 words) [view diff] exact match in snippet view article find links to article
phosphorylation from ATP synthesis by dissipating the mitochondrial membrane potential as heat, also referred to as the mitochondrial proton leak. UCPs facilitate
Cellular neuroscience (1,366 words) [view diff] exact match in snippet view article find links to article
which re-polarizes the membrane potential towards the resting membrane potential. Repolarization of the membrane potential continues, resulting in an
Mitochondrial uncoupling protein 4 (859 words) [view diff] exact match in snippet view article find links to article
inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs
Dendrite (2,775 words) [view diff] exact match in snippet view article find links to article
potential across the neuron's plasma membrane. This change in the membrane potential will passively spread across the dendrite but becomes weaker with
ATP1A3 (1,455 words) [view diff] exact match in snippet view article find links to article
thyroid hormone stimulus regulation of resting membrane potential regulation of presynaptic membrane potential cellular response to amyloid-beta neuron projection
Channel blocker (2,998 words) [view diff] exact match in snippet view article find links to article
the flow of charged ions across the membrane and therefore mediate membrane potential of the cell. Molecules that act as channel blockers are important
KCNK2 (1,421 words) [view diff] exact match in snippet view article find links to article
channel that releases potassium out of the cell to control resting membrane potential. The channel is opened by anionic lipid, certain anesthetics, membrane
Cromakalim (361 words) [view diff] exact match in snippet view article find links to article
pressure. Hyperpolarisation of smooth muscle cell membranes pulls their membrane potential away from the threshold, so making it more difficult to excite them
CLIC1 (1,193 words) [view diff] exact match in snippet view article find links to article
regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation
GRIK3 (657 words) [view diff] exact match in snippet view article find links to article
regulation of presynaptic membrane potential transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component
Inward-rectifier potassium channel (1,973 words) [view diff] exact match in snippet view article find links to article
regulating neuronal activity, by helping to stabilize the resting membrane potential of the cell. By convention, inward current (positive charge moving
GABRR1 (943 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process regulation of postsynaptic membrane potential regulation of presynaptic membrane potential Sources:Amigo
Cyclic nucleotide-gated channel alpha 1 (1,216 words) [view diff] exact match in snippet view article find links to article
closure of CNGA1/B1 channels and, therefore, hyperpolarization of the membrane potential. Cyclic nucleotide-gated ion channel GRCh38: Ensembl release 89: ENSG00000198515
Azimilide (953 words) [view diff] exact match in snippet view article find links to article
depolarization. They shift the threshold towards zero or hyperpolarize the membrane potential. Although each agent has its own properties and will have thus a different
CLIC2 (689 words) [view diff] exact match in snippet view article find links to article
regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation
TECTA (841 words) [view diff] exact match in snippet view article find links to article
deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one
ADP/ATP translocase 4 (1,607 words) [view diff] exact match in snippet view article find links to article
ADP/ATP exchange across the mitochondrial membranes and regulating membrane potential. In particular, ANT4 is essential to spermatogenesis, as it imports
CHRNA10 (326 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic
Excitatory synapse (2,550 words) [view diff] exact match in snippet view article find links to article
of that cell. Depolarization, a deviation from a neuron's resting membrane potential towards its threshold potential, increases the likelihood of an action
Kv1.1 (2,125 words) [view diff] exact match in snippet view article find links to article
regulation of presynaptic membrane potential voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component
Myometrium (630 words) [view diff] exact match in snippet view article find links to article
resting membrane potential (Vrest) of uterine smooth muscle has been recorded to be between -35 and -80 mV. As with the resting membrane potential of other
CLIC4 (1,164 words) [view diff] exact match in snippet view article find links to article
regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation
Voltage-gated proton channel (802 words) [view diff] exact match in snippet view article find links to article
hydrogen channels usually hyperpolarize the cell membrane, or makes the membrane potential more negative. A recent discovery has shown that the voltage-gated
GLRA2 (488 words) [view diff] exact match in snippet view article find links to article
transmission regulation of membrane potential response to amino acid nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO
GABRG3 (589 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
GABRR2 (609 words) [view diff] exact match in snippet view article find links to article
transmembrane transport regulation of membrane potential nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO
Brodmann area 49 (344 words) [view diff] exact match in snippet view article find links to article
are modulated by local theta rhythm, and display theta-frequency membrane potential oscillations (Glasgow & Chapman, 2007; Taube, 1995). Furthermore,
Brain mitochondrial carrier protein 1 (758 words) [view diff] exact match in snippet view article find links to article
inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs
Zona glomerulosa (712 words) [view diff] exact match in snippet view article find links to article
zona glomerulosa cells within adrenal slices spontaneously generate membrane potential oscillations of low periodicity; this innate electrical excitability
Voltage-dependent anion channel (1,698 words) [view diff] exact match in snippet view article find links to article
molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30–40 mV. VDAC facilitates
GLRB (546 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component cytoplasm integral component of membrane postsynaptic
Andersen–Tawil syndrome (2,389 words) [view diff] exact match in snippet view article find links to article
current known as IK1 which is responsible for setting the resting membrane potential of muscle cells and is therefore critical for maintaining the normal
CHRND (744 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane
Goldman equation (2,114 words) [view diff] exact match in snippet view article find links to article
charge determines the sign of the membrane potential contribution. During an action potential, although the membrane potential changes about 100mV, the concentrations
CHRNB1 (673 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane acetylcholine-gated
HCN channel (1,554 words) [view diff] exact match in snippet view article find links to article
and K+, and are constitutively open at voltages near the resting membrane potential. HCN channels are encoded by four genes (HCN1, 2, 3, 4) and are widely
GABRG1 (896 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
Group C nerve fiber (2,563 words) [view diff] exact match in snippet view article find links to article
membrane potential of unmyelinated axons like C fibers. Moalem-Taylor et al. experimentally used chemical modulators with known effects on membrane potential
Bcl-2-associated X protein (2,112 words) [view diff] exact match in snippet view article find links to article
voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated
CHRNB4 (984 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component
KCNH8 (331 words) [view diff] exact match in snippet view article find links to article
S2CID 219195192. Baxter DF, Kirk M, Garcia AF, et al. (2002). "A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels"
GABRE (762 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
Hyperkalemic periodic paralysis (1,073 words) [view diff] exact match in snippet view article find links to article
original resting membrane potential. In the presence of hyperkalemia, which causes an additional chronic depolarization of the membrane potential, this sodium
GABRB1 (1,100 words) [view diff] exact match in snippet view article find links to article
chemical synaptic transmission regulation of membrane potential nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO
Molecular neuroscience (3,050 words) [view diff] exact match in snippet view article find links to article
ions into a neuron, resulting in a depolarization from the resting membrane potential of a neuron to lead to a graded potential or action potential, depending
CHRNB2 (1,060 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component
CHRNB2 (1,060 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component
Synaptic potential (1,541 words) [view diff] exact match in snippet view article find links to article
EPSPs to both depolarize the postsynaptic membrane from its resting membrane potential to its threshold and counterbalance the concurrent IPSPs that hyperpolarize
CHRNA9 (745 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component synapse integral component of membrane cell junction
CHRNA1 (1,173 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane membrane synapse
Soliton model in neuroscience (3,686 words) [view diff] exact match in snippet view article find links to article
ions to enter the cell (inward current). The resulting decrease in membrane potential opens nearby voltage-gated sodium channels, thus propagating the action
Stimulus (physiology) (3,935 words) [view diff] exact match in snippet view article
permeable to chloride ions, making the membrane potential of the cell negative; a negative membrane potential makes it more difficult for the cell to
CHRNE (1,339 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane
Gamma-aminobutyric acid receptor subunit gamma-2 (1,397 words) [view diff] exact match in snippet view article find links to article
signal transduction regulation of membrane potential nervous system process regulation of postsynaptic membrane potential inhibitory synapse assembly Sources:Amigo
GABRD (1,583 words) [view diff] exact match in snippet view article find links to article
transmission signal transduction regulation of membrane potential nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO
Melainabacteria (477 words) [view diff] exact match in snippet view article find links to article
electron transport chains but have multiple methods to generate a membrane potential which can then produce ATP via ATP synthase. They are able to use
Bcl-2 homologous antagonist killer (2,595 words) [view diff] exact match in snippet view article find links to article
mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with
GABRA5 (1,057 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
KCNC2 (597 words) [view diff] exact match in snippet view article find links to article
voltage-gated ion channel activity involved in regulation of presynaptic membrane potential Cellular component integral component of membrane vesicle perikaryon
Uterine contraction (1,071 words) [view diff] exact match in snippet view article find links to article
resting membrane potential (Vrest) of uterine smooth muscle has been recorded to be between −35 and −80 mV. As with the resting membrane potential of other
GABRA6 (897 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
GABRA4 (738 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
Halorhodopsin (737 words) [view diff] exact match in snippet view article find links to article
green/yellow light to move chloride ions into the cell, overcoming the membrane potential. Beside chlorides it transports other halides and nitrates into the
GRID1 (720 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane cell junction postsynaptic
Morris–Lecar model (992 words) [view diff] exact match in snippet view article find links to article
hyperpolarizing current is carried by K+. Activation gates follow changes in membrane potential sufficiently rapidly that the activating conductance can instantaneously
KCNK6 (723 words) [view diff] exact match in snippet view article find links to article
component of plasma membrane Biological process regulation of resting membrane potential potassium ion transport regulation of ion transmembrane transport
Protonophore (487 words) [view diff] exact match in snippet view article find links to article
Protonophores uncouple oxidative phosphorylation via a decrease in the membrane potential of the inner membrane of mitochondria. They stimulate mitochondria
Mechanotransduction (3,069 words) [view diff] exact match in snippet view article find links to article
channels to open and produce a transduction current that changes the membrane potential of the cell. Typically the mechanical stimulus gets filtered in the
Gamma-aminobutyric acid receptor subunit alpha-1 (1,035 words) [view diff] exact match in snippet view article find links to article
postsynaptic membrane potential ion transmembrane transport signal transduction chemical synaptic transmission regulation of membrane potential nervous system
CHRNB3 (746 words) [view diff] exact match in snippet view article find links to article
synaptic transmission signal transduction regulation of postsynaptic membrane potential excitatory postsynaptic potential cation transmembrane transport ion
Synaptic gating (3,246 words) [view diff] exact match in snippet view article find links to article
hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred
Summation (neurophysiology) (2,291 words) [view diff] exact match in snippet view article
postsynaptic neuron. As long as the membrane potential is below threshold for firing impulses, the membrane potential can summate inputs. That is, if the
GABBR1 (1,220 words) [view diff] exact match in snippet view article find links to article
neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Cellular component cytoplasm integral component of membrane G protein-coupled
KCNK1 (795 words) [view diff] exact match in snippet view article find links to article
conduction potassium ion transmembrane transport regulation of resting membrane potential stabilization of membrane potential Sources:Amigo / QuickGO
Diastolic depolarization (338 words) [view diff] exact match in snippet view article find links to article
action. The amount of net inward current required to move the cell membrane potential during the pacemaker phase is extremely small, in the order of few
Prostomatea (135 words) [view diff] exact match in snippet view article find links to article
00290.x. PMID 18070326. Rudberg P, Sand O (February 2000). "Bistable membrane potential of the ciliate Coleps hirtus". The Journal of Experimental Biology
Parasubiculum (349 words) [view diff] exact match in snippet view article find links to article
are modulated by local theta rhythm, and display theta-frequency membrane potential oscillations (Glasgow & Chapman, 2007; Taube, 1995). Furthermore,
Synaptosome (929 words) [view diff] exact match in snippet view article find links to article
have become a common tool for drug testing. They maintain a normal membrane potential, contain presynaptic receptors, translocate metabolites and ions,
CHRNA5 (905 words) [view diff] exact match in snippet view article find links to article
postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport regulation of synaptic vesicle exocytosis regulation of membrane potential
SLC8B1 (325 words) [view diff] exact match in snippet view article find links to article
antiporter activity involved in regulation of cardiac muscle cell membrane potential Cellular component integral component of membrane membrane plasma
PINK1 (2,687 words) [view diff] exact match in snippet view article find links to article
membrane potential. Mitochondria with a strong, healthy membrane potential were more likely to undergo fusion than mitochondria with a low membrane potential
Mitochondrial membrane transport protein (3,403 words) [view diff] exact match in snippet view article find links to article
restricts the movement of all molecules. The two membranes also vary in membrane potential and pH. These factors play a role in the function of mitochondrial
Carbonyl cyanide m-chlorophenyl hydrazone (499 words) [view diff] exact match in snippet view article find links to article
A. Holoubek; K. Sigler (1999). "Factors and processes involved in membrane potential build-up in yeast: diS-C3(3) assay". The International Journal of
CHRNA2 (864 words) [view diff] exact match in snippet view article find links to article
postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport chemical synaptic transmission regulation of membrane potential nervous
Catasetum fimbriatum (434 words) [view diff] exact match in snippet view article find links to article
flower this stimulates the antennae triggering a quick change in membrane potential. This propagates an action potential that results in an increase in
LTP induction (1,102 words) [view diff] exact match in snippet view article find links to article
roughly equal, so when this channel is open the resulting change in membrane potential tends towards zero (a bit more than halfway between the equilibrium
GRIN3A (1,017 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component synapse integral component of membrane NMDA selective
GRIK5 (825 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic
GRIN2C (1,125 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane
KCNJ10 (1,321 words) [view diff] exact match in snippet view article find links to article
synaptic plasticity central nervous system myelination regulation of membrane potential regulation of ion transmembrane transport ion transport potassium
GRIK2 (3,056 words) [view diff] exact match in snippet view article find links to article
regulation of presynaptic membrane potential transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component
Avoidance reaction (206 words) [view diff] exact match in snippet view article find links to article
potentials. The simplest explanation for the avoidance reaction is that membrane potential controls the influx of calcium ions, which regulates the beat frequency
Neural backpropagation (2,261 words) [view diff] exact match in snippet view article find links to article
channels and are transmembrane channels that help maintain the cell's membrane potential (Cai 2007). Typically, they play a crucial role in returning the cell
Spontaneous potential (1,163 words) [view diff] exact match in snippet view article find links to article
(EC) is the sum of liquid junction or diffusion potential (EJ), and membrane potential (EM) Liquid junction potential is established at the direct contact
Proguanil (1,029 words) [view diff] exact match in snippet view article find links to article
cascade. This is commonly referred to as "collapse of the mitochondrial membrane potential." Proguanil lowers the effective concentration of atovaquone needed
KCNE3 (3,022 words) [view diff] exact match in snippet view article find links to article
unless the cell is held at a strongly hyperpolarizing (negative) membrane potential. The ability of KCNQ1-KCNE3 channels to remain open at weakly negative
HTR3D (192 words) [view diff] exact match in snippet view article find links to article
transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
CHRNA6 (952 words) [view diff] exact match in snippet view article find links to article
transduction chemical synaptic transmission regulation of postsynaptic membrane potential excitatory postsynaptic potential cation transmembrane transport ion
UCP3 (1,932 words) [view diff] exact match in snippet view article find links to article
synthesis of ATP, and dissipating energy stored in the mitochondrial membrane potential as heat. Uncoupling proteins also reduce generation of reactive oxygen
KCNC1 (1,183 words) [view diff] exact match in snippet view article find links to article
voltage-gated ion channel activity involved in regulation of presynaptic membrane potential Cellular component integral component of membrane membrane voltage-gated
KCND2 (1,211 words) [view diff] exact match in snippet view article find links to article
voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic
SLC26A8 (418 words) [view diff] exact match in snippet view article find links to article
differentiation oxalate transport sulfate transport regulation of membrane potential regulation of intracellular pH ion transport anion transport multicellular
Kir2.6 (143 words) [view diff] exact match in snippet view article find links to article
Inwardly rectifying potassium channels, such as Kir2.6, maintain resting membrane potential in excitable cells and aid in repolarization of cells following depolarization
GABRA3 (2,246 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /
GRIA1 (1,356 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential amyloid-beta binding signaling receptor activity Cellular component
Aconitine (3,360 words) [view diff] exact match in snippet view article find links to article
the membrane potential causes the opening (activation) of potassium channels and potassium efflux, which results in repolarization of the membrane potential
Atovaquone/proguanil (939 words) [view diff] exact match in snippet view article find links to article
parasitic electron transport chain, collapsing the mitochondrial membrane potential. The malarial electron transport chain does not contribute significantly
Intermembrane space (1,064 words) [view diff] exact match in snippet view article find links to article
voltage gradient (membrane potential). The pH in the IMS is about 0.7 unit lower than the one in the matrix and the membrane potential of the IMS side becomes
Glycine receptor, alpha 1 (1,165 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic
HTR3C (275 words) [view diff] exact match in snippet view article find links to article
transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
KCNK4 (1,740 words) [view diff] exact match in snippet view article find links to article
TRAAK channels play a critical role in the maintenance of the resting membrane potential in excitable cell types. More recently, TRAAK channels have been identified
GABRA2 (1,826 words) [view diff] exact match in snippet view article find links to article
regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential inhibitory synapse
Exponential integrate-and-fire (1,467 words) [view diff] exact match in snippet view article find links to article
where V {\displaystyle V} is the membrane potential, V T {\displaystyle V_{T}} is the intrinsic membrane potential threshold, τ m {\displaystyle \tau
Electrical tuning (394 words) [view diff] exact match in snippet view article find links to article
increases, but then with the exit of the K+ the cell overshoots the membrane potential and hyperpolarizes. Different cells have different delays for K+ leaving
Inner mitochondrial membrane (936 words) [view diff] exact match in snippet view article find links to article
protein MIC60/Mic60 (formerly Mitofilin/Fcj1) leads to a reduced inner membrane potential and impaired growth and to dramatically aberrant inner membrane structures
Halcurin (581 words) [view diff] exact match in snippet view article find links to article
the extracellular site 3 on the voltage gated sodium channels in a membrane potential-dependent manner. The polypeptide toxin halcurin is named after its
CHRNA7 (1,547 words) [view diff] exact match in snippet view article find links to article
factor production response to nicotine regulation of postsynaptic membrane potential excitatory postsynaptic potential positive regulation of protein phosphorylation
HTR3E (320 words) [view diff] exact match in snippet view article find links to article
transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
GRIN1 (1,045 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential amyloid-beta binding glutamate-gated calcium ion channel activity
Transmembrane channels (555 words) [view diff] exact match in snippet view article find links to article
is the gated channel which requires a trigger, such as a change in membrane potential in voltage-gated channels, to unlock or lock the pore opening. Voltage-gated
Mitochondrial matrix (1,865 words) [view diff] exact match in snippet view article find links to article
the concentration of ions such as Ca2+ driven by the mitochondrial membrane potential. The membrane only allows nonpolar molecules such as CO2 and O2 and
Cardiolipin (3,390 words) [view diff] exact match in snippet view article find links to article
indicator of CL content in mitochondria. However, NAO is influenced by membrane potential and/or the spatial arrangement of CL, so it's not proper to use NAO
Purkinje cell (3,114 words) [view diff] exact match in snippet view article find links to article
"Purkinje cells in awake behaving animals operate at the up state membrane potential". Nature Neuroscience. 9 (4): 459–461. doi:10.1038/nn0406-459. PMID 16568098
GRIK1 (1,654 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane cell junction plasma
Beta-1 adrenergic receptor (1,704 words) [view diff] exact match in snippet view article find links to article
neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane endosome membrane
Γ-Aminobutyric acid (5,251 words) [view diff] exact match in snippet view article find links to article
cell's membrane less negative), shunting (has no effect on the cell's membrane potential), or inhibitory/hyperpolarizing (makes the cell's membrane more negative)
KCNT2 (263 words) [view diff] exact match in snippet view article find links to article
transmembrane transport potassium ion transport ion transport regulation of membrane potential potassium ion export across plasma membrane Sources:Amigo / QuickGO
KCNH3 (304 words) [view diff] exact match in snippet view article find links to article
transduction regulation of ion transmembrane transport regulation of membrane potential potassium ion transmembrane transport potassium ion transport ion
Zinc-activated ion channel (211 words) [view diff] exact match in snippet view article find links to article
transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
KCNH6 (363 words) [view diff] exact match in snippet view article find links to article
integral component of plasma membrane Biological process regulation of membrane potential potassium ion transport regulation of ion transmembrane transport
Lq2 (627 words) [view diff] exact match in snippet view article find links to article
ROMK1. This ion channel contributes to the regulation of the resting membrane potential. Since all potassium channels share the same ion conducting outer
KCNH4 (247 words) [view diff] exact match in snippet view article find links to article
transport potassium ion transport regulation of ion transmembrane transport transmembrane transport regulation of membrane potential Sources:Amigo / QuickGO
Sodium–hydrogen antiporter 1 (1,435 words) [view diff] exact match in snippet view article find links to article
antiporter activity involved in regulation of cardiac muscle cell membrane potential calmodulin binding GO:0001948 protein binding GO:0032947 molecular
Celivarone (1,221 words) [view diff] exact match in snippet view article find links to article
flow affect the heart's ability to contract by altering the resting membrane potential, affecting the cell's ability to conduct or transmit an action potential
Metabotropic glutamate receptor 1 (2,213 words) [view diff] exact match in snippet view article find links to article
protein-coupled receptor activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane G protein-coupled
Spike response model (3,722 words) [view diff] exact match in snippet view article find links to article
{\displaystyle \eta } of the model can be interpreted as the response of the membrane potential to an incoming spike (response kernel ε {\displaystyle \varepsilon
GRIA3 (2,070 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane endocytic vesicle
GABRR3 (401 words) [view diff] exact match in snippet view article find links to article
synaptic transmission ion transmembrane transport signal transduction regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Muscle fatigue (2,030 words) [view diff] exact match in snippet view article find links to article
potentials. The shift in K+ changes the membrane potential around the muscle fiber. The change in membrane potential causes a decrease in the release of calcium
KCNK12 (428 words) [view diff] exact match in snippet view article find links to article
regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
KCNT1 (364 words) [view diff] exact match in snippet view article find links to article
Biological process potassium ion transport ion transport potassium ion transmembrane transport regulation of membrane potential Sources:Amigo / QuickGO
KCNK13 (453 words) [view diff] exact match in snippet view article find links to article
regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
KCNK16 (390 words) [view diff] exact match in snippet view article find links to article
regulation of ion transmembrane transport ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO
KCNH7 (448 words) [view diff] exact match in snippet view article find links to article
ion transmembrane transport potassium ion transport regulation of membrane potential regulation of ion transmembrane transport Sources:Amigo / QuickGO
GRIN2A (2,079 words) [view diff] exact match in snippet view article find links to article
of protein catabolic process response to amphetamine regulation of membrane potential directional locomotion modulation of chemical synaptic transmission
GLRA3 (438 words) [view diff] exact match in snippet view article find links to article
transmembrane transport signal transduction chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Prajmaline (819 words) [view diff] exact match in snippet view article find links to article
Na-K-ATPase pump inhibition, chemical anoxia, and glycolytic blockade on membrane potential of rat optic nerve". Brain Research. 1037 (1–2): 171–9. doi:10.1016/j
KCNK7 (486 words) [view diff] exact match in snippet view article find links to article
regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
HCN3 (523 words) [view diff] exact match in snippet view article find links to article
sodium ion transport cellular response to dopamine regulation of membrane potential regulation of ion transmembrane transport ion transport potassium
The Hallmarks of Cancer (2,491 words) [view diff] exact match in snippet view article find links to article
likely contributes to the deactivation of mitochondria. Mitochondrial membrane potential is hyperpolarized to prevent voltage-sensitive permeability transition
KCNK17 (451 words) [view diff] exact match in snippet view article find links to article
regulation of ion transmembrane transport ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO
KCNK10 (534 words) [view diff] exact match in snippet view article find links to article
transmembrane transport memory ion transport signal transduction stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
Hypokalemia (3,510 words) [view diff] exact match in snippet view article find links to article
the resting membrane potential. This hyperpolarization is caused by the effect of the altered potassium gradient on resting membrane potential as defined
Dinoseb (1,982 words) [view diff] exact match in snippet view article find links to article
words: The proton gradient is lower, so the membrane potential will be lower. As the membrane potential is the driving force for the production of ATP
Neurotensin receptor 2 (656 words) [view diff] exact match in snippet view article find links to article
component of plasma membrane membrane Biological process regulation of membrane potential phospholipase C-activating G protein-coupled receptor signaling pathway
Forskolin (724 words) [view diff] exact match in snippet view article find links to article
regulation of Bcl-2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release". Cell Biology International. 30 (11): 940–6
Translocase of the inner membrane (944 words) [view diff] exact match in snippet view article find links to article
inner mitochondrial membrane in a potential-dependent fashion. The membrane potential is necessary for both insertion of the precursor into the carrier
Denervation (1,641 words) [view diff] exact match in snippet view article find links to article
electrical induction in denervated muscles. Changes in the resting membrane potential involving denervated muscles presents mild depolarization when a muscle
Muscarinic acetylcholine receptor M1 (2,066 words) [view diff] exact match in snippet view article find links to article
neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential G protein-coupled serotonin receptor activity neurotransmitter receptor
Cyclic nucleotide-gated channel alpha 4 (415 words) [view diff] exact match in snippet view article find links to article
of smell ion transport ion transmembrane transport regulation of membrane potential potassium ion transmembrane transport cation transmembrane transport
GABRP (550 words) [view diff] exact match in snippet view article find links to article
transduction chloride transmembrane transport chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Cyclic nucleotide-gated channel alpha 2 (533 words) [view diff] exact match in snippet view article find links to article
plasma membrane Biological process response to stimulus regulation of membrane potential ion transport sensory perception of smell ion transmembrane transport
CNGB1 (627 words) [view diff] exact match in snippet view article find links to article
regulation of rhodopsin mediated signaling pathway regulation of membrane potential cation transport ion transport photoreceptor cell outer segment organization
KCNK15 (481 words) [view diff] exact match in snippet view article find links to article
transmembrane transport cardiac conduction ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
KCNU1 (529 words) [view diff] exact match in snippet view article find links to article
transmembrane transport potassium ion transmembrane transport sperm-egg recognition reproductive process regulation of membrane potential Sources:Amigo / QuickGO
KIF5B (1,013 words) [view diff] exact match in snippet view article find links to article
microtubule positive regulation of potassium ion transport regulation of membrane potential positive regulation of synaptic transmission, GABAergic axon guidance
Variation potential (686 words) [view diff] exact match in snippet view article find links to article
potential, like an action potential, is a temporary change in the membrane potential of the plant cell by depolarization and consequent repolarization
KCNK18 (540 words) [view diff] exact match in snippet view article find links to article
transport potassium ion transmembrane transport stabilization of membrane potential potassium ion export across plasma membrane Sources:Amigo / QuickGO
Nervous system network models (5,144 words) [view diff] exact match in snippet view article find links to article
extensively used and is based on two generic models, one of cell membrane potential Goldman (1943) and Hodgkin and Katz (1949), and the other based on
BmKAEP (752 words) [view diff] exact match in snippet view article find links to article
Subsequently, the sodium current amplitude decreases, due to the membrane potential depolarization, thus suppressing action potentials. BmK venom induces
Matteo Carandini (794 words) [view diff] exact match in snippet view article find links to article
the relationship between synaptic excitation, synaptic inhibition, membrane potential, and firing rate in visual cortex and discovered that prolonged visual
Electroporation (5,021 words) [view diff] exact match in snippet view article find links to article
field, a large membrane potential at the two pole of a cell can be created. In the 1970s it was discovered that when a membrane potential reached a critical
Lorcainide (1,015 words) [view diff] exact match in snippet view article find links to article
found in high concentrations in the ventricular myocytes, open at a membrane potential of −80 mv in typical cardiac rhythm. This will result in a rapid upstroke
Guillardia (456 words) [view diff] exact match in snippet view article find links to article
channelrhodopsins were isolated from Guillardia theta that hyperpolarize neuronal membrane potential and are potent inhibitors of neural activity. Bruce A. Curtis; Goro
Spike potential (211 words) [view diff] exact match in snippet view article find links to article
resting membrane potential of the gastrointestinal smooth muscle becomes more positive than about -40 millivolts (the normal resting membrane potential in
SLC25A39 (522 words) [view diff] exact match in snippet view article find links to article
"Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial
Pyrazinamide (2,317 words) [view diff] exact match in snippet view article find links to article
The accumulation of pyrazinoic acid was also suggested to disrupt membrane potential and interfere with energy production, necessary for survival of M
CACNA1G (436 words) [view diff] exact match in snippet view article find links to article
depolarization during action potential calcium ion import regulation of membrane potential regulation of ion transmembrane transport regulation of atrial cardiac
GLRX (884 words) [view diff] exact match in snippet view article find links to article
nucleobase-containing small molecule interconversion positive regulation of membrane potential protein deglutathionylation cell redox homeostasis electron transport
KCNK5 (626 words) [view diff] exact match in snippet view article find links to article
ion transmembrane transport excretion ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO
GABRQ (673 words) [view diff] exact match in snippet view article find links to article
neurotransmitter transport ion transmembrane transport chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Muscle contraction (7,093 words) [view diff] exact match in snippet view article find links to article
quickly jumps from the resting membrane potential of -90mV to as high as +75mV as sodium enters. The membrane potential then becomes hyperpolarized when
Sodium-calcium exchanger (2,216 words) [view diff] exact match in snippet view article find links to article
cardiac arrhythmia. Since the transport is electrogenic (alters the membrane potential), depolarization of the membrane can reverse the exchanger's direction
KCNH5 (535 words) [view diff] exact match in snippet view article find links to article
transition of mitotic cell cycle signal transduction regulation of membrane potential regulation of ion transmembrane transport ion transport potassium
Ischemic cell death (1,093 words) [view diff] exact match in snippet view article find links to article
increase in UCP-2 levels leads to a rapid decrease in mitochondrial membrane potential, reducing mitochondrial NADH and intracellular ATP levels, initiating
Veratridine (1,207 words) [view diff] exact match in snippet view article find links to article
turning the membrane potential to a more positive one and also modifies the effect of progesterone on [Ca2+]i and sperm membrane potential. The activation
Cardiac physiology (5,774 words) [view diff] exact match in snippet view article find links to article
that allow a normal and slow influx of sodium ions that causes the membrane potential to rise slowly from an initial value of −60 mV up to about –40 mV
Anion exchange transporter (536 words) [view diff] exact match in snippet view article find links to article
transport sulfate transport gastric acid secretion regulation of membrane potential regulation of intracellular pH ion transport anion transport bicarbonate
Brian M. Salzberg (2,137 words) [view diff] exact match in snippet view article find links to article
colleagues, they established what would be the first link between membrane potential and second messenger activation. Other contributions include the first
Metabotropic glutamate receptor 5 (3,215 words) [view diff] exact match in snippet view article find links to article
protein-coupled receptor activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity involved in regulation of postsynaptic
BRL-32872 (812 words) [view diff] exact match in snippet view article find links to article
orally or via intravenous injection, and has no effect on resting membrane potential. The effects BRL-32872 have been well documented in animal models
Adenosine triphosphate (4,756 words) [view diff] exact match in snippet view article find links to article
glycolytic rates and ATP hydrolysis), contributes to mitochondrial membrane potential and directly drives ATP synthesis. Most of the ATP synthesized in
Sodium-dependent phosphate transport protein 2A (340 words) [view diff] exact match in snippet view article find links to article
regulation of sodium-dependent phosphate transport positive regulation of membrane potential protein homooligomerization cellular phosphate ion homeostasis sodium
ATP1A4 (934 words) [view diff] exact match in snippet view article find links to article
transmembrane electrochemical gradient sodium ion transport regulation of membrane potential ion transport potassium ion transport regulation of cellular pH spermatogenesis
Philip A. Gale (1,573 words) [view diff] exact match in snippet view article find links to article
and the development of anion transporters that can be switched by membrane potential gradients or by the presence of reducing agents found in higher concentrations
HTR3B (1,020 words) [view diff] exact match in snippet view article find links to article
transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Hair cell (3,453 words) [view diff] exact match in snippet view article find links to article
neurotransmitter release in response to a change of as little as 100 μV in membrane potential. Hair cells are also able to distinguish tones through one of two
PYCR1 (594 words) [view diff] exact match in snippet view article find links to article
matrix mitochondrion Biological process regulation of mitochondrial membrane potential cellular response to oxidative stress negative regulation of hydrogen
Slow-wave potential (1,150 words) [view diff] exact match in snippet view article find links to article
velocities in the stomach due to the existence of a gradient of resting membrane potential gradient, interstitial cells of Cajal distributions, and gastric wall
Ralph W. Gerard (1,283 words) [view diff] exact match in snippet view article find links to article
Biochem J., 23, pp. 738–47 (1929) G. Ling & R.W. Gerard, The normal membrane potential of frog sartorius fibers, in: J. Cell. Comp. Physiol., 34, pp. 383–96
Ajmaline (918 words) [view diff] exact match in snippet view article find links to article
refractory period), and therefore makes it take more time for the membrane potential to get below the threshold level so the action potential can be re-fired
Steady state (biochemistry) (1,421 words) [view diff] exact match in snippet view article
ions move across the cell membrane such that a constant resting membrane potential is achieved; this is ionic steady state. In the pump-leak model of
Mary Helen Goldsmith (901 words) [view diff] exact match in snippet view article find links to article
during transport of polar chemicals, intracellular measurements of membrane potential, and activation of potassium channels. Goldsmith, M H M (June 1977)
Cyclic nucleotide gated channel beta 3 (818 words) [view diff] exact match in snippet view article find links to article
integral component of plasma membrane Biological process regulation of membrane potential cation transport ion transport cation transmembrane transport signal
KCNS3 (781 words) [view diff] exact match in snippet view article find links to article
main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The
Polarized membrane (159 words) [view diff] case mismatch in snippet view article find links to article
00003-8. ISBN 978-0-12-388425-1. McCormick, David A. (2014). "Membrane Potential and Action Potential". From Molecules to Networks. Elsevier. pp. 351–376
Saltatory conduction (672 words) [view diff] exact match in snippet view article find links to article
Goldman equation – Generalization of the Nernst equation for the membrane potential Hindmarsh–Rose model – Of the spiking-bursting behavior of a neuron
Transcellular transport (697 words) [view diff] exact match in snippet view article find links to article
David R. (2012). "Plasma membrane. membrane transport, and resting membrane potential". Medical physiology : principles for clinical medicine (4th ed.,
Georg Nagel (981 words) [view diff] exact match in snippet view article find links to article
illumination with blue light caused a strong depolarization of the membrane potential. Following this proof-of-principle publication, ChR2 was expressed
Douglas G. McMahon (2,212 words) [view diff] exact match in snippet view article find links to article
molluscan eye exhibited circadian rhythms in spike frequency and membrane potential, indicating they are the clock neurons. He became the 1986 winner
Excitatory amino acid transporter 4 (563 words) [view diff] exact match in snippet view article find links to article
membrane Biological process chemical synaptic transmission regulation of membrane potential ion transport glutamate secretion aspartate transmembrane transport
Sulfonylurea receptor (646 words) [view diff] exact match in snippet view article find links to article
on the tissue in which the KATP channel is expressed, altering the membrane potential can trigger a variety of downstream events. For example, in pancreatic
Maddika Subba Reddy (786 words) [view diff] exact match in snippet view article find links to article
independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent
Manganese(II) chloride (755 words) [view diff] exact match in snippet view article
Characterization of size distribution, trapped volume and ability to maintain a membrane potential" (PDF), Biochimica et Biophysica Acta (BBA) - Biomembranes, 812 (1):
Transcranial direct-current stimulation (5,730 words) [view diff] exact match in snippet view article find links to article
changes brain function is either by causing the neuron’s resting membrane potential to depolarize or hyperpolarize. When positive stimulation (anodal
CHRNA3 (1,037 words) [view diff] exact match in snippet view article find links to article
locomotory behavior regulation of smooth muscle contraction regulation of membrane potential regulation of acetylcholine secretion, neurotransmission synaptic
Cyclic nucleotide-gated channel alpha 3 (968 words) [view diff] exact match in snippet view article find links to article
projection Biological process response to stimulus regulation of membrane potential cation transport response to magnesium ion ion transport ion transmembrane
TRPM4 (454 words) [view diff] exact match in snippet view article find links to article
positive regulation of canonical Wnt signaling pathway regulation of membrane potential cation transport ion transport protein sumoylation dendritic cell
KCNN4 (1,297 words) [view diff] exact match in snippet view article find links to article
process defense response phospholipid translocation stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
HCN2 (1,094 words) [view diff] exact match in snippet view article find links to article
transport sodium ion transport cell-cell signaling regulation of membrane potential regulation of ion transmembrane transport ion transport potassium
CACNG2 (1,204 words) [view diff] exact match in snippet view article find links to article
membrane hyperpolarization transmission of nerve impulse regulation of membrane potential regulation of ion transmembrane transport membrane depolarization
KCNK3 (1,047 words) [view diff] exact match in snippet view article find links to article
ion concentration chemical synaptic transmission stabilization of membrane potential regulation of signaling receptor activity Sources:Amigo / QuickGO
H1 neuron (1,654 words) [view diff] exact match in snippet view article find links to article
increasing the dynamic range over which H1 operates. Changes in H1 axonal membrane potential is proportional to the amplitude of optic image velocity. However
GABRB3 (3,080 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane
ASIC2 (984 words) [view diff] exact match in snippet view article find links to article
involved in sensory perception sodium ion transport regulation of membrane potential regulation of ion transmembrane transport response to mechanical stimulus
CLCNKA (1,284 words) [view diff] exact match in snippet view article find links to article
thin and thick ascending limb of the nephrons. Experimentally, the membrane potential at which the channels show no net movement of ions at a given chloride
Decynium-22 (759 words) [view diff] exact match in snippet view article find links to article
Kucheryavykh L, Sanabria P, Jiménez-Rivera C, Struganova I, et al. (2010). "Membrane potential and pH-dependent accumulation of decynium-22 (1,1′-diethyl-2,2′-cyanine
Histrionicotoxins (1,487 words) [view diff] exact match in snippet view article find links to article
histrionicotoxin on end-plate potential have shown that the compound hinders membrane potential propagation, but has emergent characteristics with membrane hyperpolarizations
CHRFAM7A (785 words) [view diff] exact match in snippet view article find links to article
synaptic transmission synaptic transmission, cholinergic regulation of membrane potential nervous system process response to hypoxia cognition cellular calcium
HTR3A (964 words) [view diff] exact match in snippet view article find links to article
transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Kir6.2 (1,090 words) [view diff] exact match in snippet view article find links to article
regulation of insulin secretion response to testosterone regulation of membrane potential cellular response to tumor necrosis factor regulation of ion transmembrane
SLC26A6 (804 words) [view diff] exact match in snippet view article find links to article
fluid transport angiotensin-activated signaling pathway regulation of membrane potential regulation of intracellular pH cellular response to fructose stimulus
Depolarization (disambiguation) (85 words) [view diff] exact match in snippet view article
to: Depolarization, a decrease in the absolute value of a cell's membrane potential Depolarizer, a substance used to depolarize an electrochemical cell
Nav1.8 (3,611 words) [view diff] exact match in snippet view article find links to article
Slaughter RS, Garcia ML, Köhler MG (February 2006). "A high-capacity membrane potential FRET-based assay for NaV1.8 channels". Assay and Drug Development
Dicycloplatin (992 words) [view diff] case mismatch in snippet view article find links to article
properties of Hep G2 cells are observed: the declination of Mitochondria Membrane Potential, the release of cytochrome c from mitochondria to cytosol, the activation
Nitrendipine (672 words) [view diff] exact match in snippet view article find links to article
calcium channels in smooth muscle cells because of its lower resting membrane potential. The nitrendipine diffuses into the membrane and binds to its high
Bioelectricity (18,126 words) [view diff] exact match in snippet view article find links to article
(2014). "Single cell wound generates electric current circuit and cell membrane potential variations that requires calcium influx". Integr. Biol. 6 (7): 662–72
Forasartan (938 words) [view diff] exact match in snippet view article find links to article
during the plateau component, increasing the intracellular calcium and membrane potential which sustain depolarization and contraction. Forasartan is a competitive
Dofetilide (1,280 words) [view diff] exact match in snippet view article find links to article
upstroke of phase 0 depolarization), conduction velocity, or the resting membrane potential. There is a dose-dependent increase in the QT interval and the corrected
VDAC1 (4,089 words) [view diff] exact match in snippet view article find links to article
in increased mitochondrial permeability, disrupted mitochondrial membrane potential, elevated ROS production, cell death, and neuronal degeneration. VDAC1
Mitophagy (2,662 words) [view diff] exact match in snippet view article find links to article
mitochondria, the inner mitochondrial membrane becomes depolarized. This membrane potential is necessary for the TIM-mediated protein import. In depolarized mitochondria
Spermidine (1,241 words) [view diff] exact match in snippet view article find links to article
biological processes, (such as Ca2+, Na+, K+ -ATPase) thus maintaining membrane potential and controlling intracellular pH and volume. Spermidine regulates
ASIC1 (1,327 words) [view diff] exact match in snippet view article find links to article
sodium ion transmembrane transport sodium ion transport regulation of membrane potential cation transport memory sensory perception of sour taste ion transport
Crotoxin (2,224 words) [view diff] exact match in snippet view article find links to article
with many processes, including vesicle fusion and the mitochondrial membrane potential. Both these processes are important for acetylcholine homeostasis
Tedisamil (827 words) [view diff] exact match in snippet view article find links to article
the potassium channels are responsible for restoring the resting membrane potential during an action potential, lengthening their inactivation will stop
CHRNG (680 words) [view diff] exact match in snippet view article find links to article
postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport chemical synaptic transmission regulation of membrane potential nervous
Glycine receptor (1,468 words) [view diff] exact match in snippet view article find links to article
as it happens in mature adults. The efflux of chloride causes the membrane potential to become more positive, or depolarized. As the cells mature, the
Reuptake (1,876 words) [view diff] exact match in snippet view article find links to article
leading to transmembrane charge movement that is enhanced by the membrane potential. These forces pull the neurotransmitter substrate into the cell, even
Calcium channel, voltage-dependent, T type, alpha 1H subunit (1,255 words) [view diff] exact match in snippet view article find links to article
heart contraction aldosterone biosynthetic process regulation of membrane potential regulation of ion transmembrane transport muscle organ development
HCN4 (1,304 words) [view diff] exact match in snippet view article find links to article
sodium ion transport SA node cell action potential regulation of membrane potential regulation of ion transmembrane transport cation transport ion transport
Mitochondrial fusion (2,367 words) [view diff] exact match in snippet view article find links to article
defects such as poor cell growth, heterogeneity of mitochondrial membrane potential and decreased cellular respiration. Mitochondrial fusion plays an
HCN1 (1,380 words) [view diff] exact match in snippet view article find links to article
protein localization ion transport sodium ion transport regulation of membrane potential sodium ion transmembrane transport potassium ion transmembrane transport
Phenoptosis (1,406 words) [view diff] exact match in snippet view article find links to article
mitochondria produce reactive oxygen species ROS, leading to loss of membrane potential within the mitochondria and death of the cell. Amoeba Dictyostelium
Antillatoxin (1,439 words) [view diff] exact match in snippet view article find links to article
exact mechanism is still unclear, as antillatoxin’s effect on the membrane potential is not sufficient to relieve the NMDA receptor block by magnesium
Digoxin (5,661 words) [view diff] exact match in snippet view article find links to article
increases in the sinoatrial and AV nodes. A less negative resting membrane potential is made, leading to increased irritability. The conduction velocity
Chloride anion exchanger (1,135 words) [view diff] exact match in snippet view article find links to article
elevation membrane hyperpolarization sulfate transport regulation of membrane potential regulation of intracellular pH ion transport anion transport bicarbonate
Dendritic spine (5,314 words) [view diff] exact match in snippet view article find links to article
representation, spine head voltage is the local spatial average of membrane potential in adjacent spines. The formulation maintains the feature that there
DiI (969 words) [view diff] no match in snippet view article find links to article
with tails much shorter than 12C, usually less than 7C are used as membrane-potential sensors for mitochondria, based on their vertical sinking into or
BNIP3 (2,667 words) [view diff] exact match in snippet view article find links to article
BNIP3 is necessary for clearing dysfunctional mitochondria with low membrane potential and reducing the build up of ROS to promote cell survival. BNIP3L
GABRB2 (6,283 words) [view diff] exact match in snippet view article find links to article
transmembrane transport regulation of membrane potential nervous system process regulation of postsynaptic membrane potential inhibitory synapse assembly Sources:Amigo
Vasodilation (2,204 words) [view diff] exact match in snippet view article find links to article
Hyperpolarization-mediated (Calcium channel blocker) Changes in the resting membrane potential of the cell affects the level of intracellular calcium through modulation
GalP (protein) (1,807 words) [view diff] exact match in snippet view article
protons are charged molecules, their import or export could disrupt the membrane potential of the cell (14). However, simultaneous import and export of protons
Delta atracotoxin (2,265 words) [view diff] exact match in snippet view article find links to article
spontaneous repetitive firing, but does not depolarize the resting membrane potential. Effects on the autonomic nervous system, including vomiting, profuse
Procainamide (2,072 words) [view diff] exact match in snippet view article find links to article
refractory period. This results in a disturbance in the artificial membrane potential and leads to a supraventricular tachycardia which induces failure
KCNK9 (1,545 words) [view diff] exact match in snippet view article find links to article
Biological process potassium ion transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
NMDA receptor (11,603 words) [view diff] exact match in snippet view article find links to article
However, the NMDA receptor cation channel is blocked by Mg2+ at resting membrane potential. Magnesium unblock is not instantaneous, to unblock all available
Bcl-2-like protein 1 (2,219 words) [view diff] exact match in snippet view article find links to article
(voltage-dependent anion channels (VDACs) opening. VDACs regulate mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release
Rottlerin (1,583 words) [view diff] exact match in snippet view article find links to article
at high doses and results in depolarization of the mitochondrial membrane potential. It was found to reduce ATP levels, activate 5'-AMP-activated protein
CHRNA4 (1,160 words) [view diff] exact match in snippet view article find links to article
potential response to hypoxia cognition locomotory behavior regulation of membrane potential response to nicotine membrane depolarization nervous system process
Dendrotoxin (1,612 words) [view diff] exact match in snippet view article find links to article
the excitability of nerves and muscles by controlling the resting membrane potential and by repolarizing the membrane during action potentials. Dendrotoxin
Hibiscus (3,784 words) [view diff] exact match in snippet view article find links to article
sequential voltage calcium channels open. In response to the change in membrane potential voltage, gated potassium and chlorine channels open causing an efflux
AMPA receptor (6,711 words) [view diff] exact match in snippet view article find links to article
molecules called polyamines. Thus, when the neuron is at a depolarized membrane potential, polyamines will block the AMPAR channel more strongly, preventing
Batrachotoxin (2,096 words) [view diff] exact match in snippet view article find links to article
Voltage-sensitive sodium channels become persistently active at the resting membrane potential. Batrachotoxin kills by permanently blocking nerve signal transmission
Shimon Schuldiner (874 words) [view diff] exact match in snippet view article find links to article
brain disorders. Schuldiner, S., Rottenberg, H., and Avron, M. (1972) Membrane potential as a driving force for ATP synthesis in chloroplasts. FEBS Lett. 28
HBx (1,557 words) [view diff] exact match in snippet view article find links to article
localize to the mitochondria where HBx decreases the mitochondrial membrane potential and causes increased release of ROS. In addition, other HBV proteins
Chrysophanol (1,417 words) [view diff] exact match in snippet view article find links to article
oxidative phosphorylation which can result in decreased mitochondrial membrane potential, as well as an increase in abundance of reactive oxygen species, and
Purine nucleotide cycle (450 words) [view diff] exact match in snippet view article find links to article
activation of HIF-1α allows cardiomyocytes to sustain mitochondrial membrane potential during anoxic stress by utilizing fumarate produced by adenylosuccinate
Lethal injection (10,280 words) [view diff] exact match in snippet view article find links to article
than −70mV however as there is a raised resting membrane potential this negative membrane potential cannot be reached and the inactivation of the sodium
Silent synapse (1,613 words) [view diff] exact match in snippet view article find links to article
channel, at a place within the electrical field generated by the membrane potential. Normally, current will not flow through the NMDAR channel, even when
General anaesthetic (2,631 words) [view diff] exact match in snippet view article find links to article
modulate the potassium conductance that contributes to the resting membrane potential in neurons. Opening of these channels therefore facilitates a hyperpolarizing
TRPC3 (1,216 words) [view diff] exact match in snippet view article find links to article
maintaining a tonic inward depolarizing current that regulates resting membrane potential and promotes regular neuronal firing. Conversely, inhibiting TRPC3
Pituitary adenylate cyclase-activating peptide (1,628 words) [view diff] exact match in snippet view article find links to article
chemokine (C-C motif) ligand 5 production regulation of postsynaptic membrane potential positive regulation of cell population proliferation negative regulation
Polycystin 2 (1,068 words) [view diff] exact match in snippet view article find links to article
morphogenesis determination of left/right symmetry regulation of postsynaptic membrane potential negative regulation of ryanodine-sensitive calcium-release channel
PRDX3 (1,191 words) [view diff] exact match in snippet view article find links to article
process response to oxidative stress regulation of mitochondrial membrane potential cellular response to reactive oxygen species response to lipopolysaccharide
KCNH1 (1,566 words) [view diff] exact match in snippet view article find links to article
potassium ion transmembrane transport myoblast fusion regulation of membrane potential phosphatidylinositol-mediated signaling startle response ion transmembrane
Ankyrin-3 (1,654 words) [view diff] exact match in snippet view article find links to article
sodium ion transmembrane transporter activity positive regulation of membrane potential plasma membrane organization signal transduction Golgi to plasma membrane
Calcium signaling (2,148 words) [view diff] exact match in snippet view article find links to article
vascular diameters. The second is a rapid time dependent change in the membrane potential which leads to a very quick and uniform increase of Ca2+. This can
Phospholamban (980 words) [view diff] exact match in snippet view article find links to article
pathway involved in heart process regulation of cardiac muscle cell membrane potential regulation of the force of heart contraction by cardiac conduction
Potassium spatial buffering (2,050 words) [view diff] exact match in snippet view article find links to article
space impacts a variety of neuronal processes, such as maintenance of membrane potential, activation and inactivation of voltage gated channels, synaptic transmission
IRGs (2,805 words) [view diff] exact match in snippet view article find links to article
such as autophagy, mitochondrial fission, change in mitochondrial membrane potential and cell death. Human IRGM like its mouse counterpart, has been shown
Latrotoxin (2,266 words) [view diff] exact match in snippet view article find links to article
but also for water. This causes nerve terminal swelling. Further membrane potential disturbances occur due to permeability of small molecules, such as
Myogenic mechanism (1,080 words) [view diff] exact match in snippet view article find links to article
and close (e.g. If channels in cardiac pacemaker cells). When the membrane potential reaches depolarization threshold an action potential (AP) is fired
Local field potential (1,197 words) [view diff] exact match in snippet view article find links to article
filtering properties. Ionic diffusion, which plays an important role in membrane potential variations, can also act as a low-pass filter. Peyrache, A; Dehghani
POPDC3 (417 words) [view diff] exact match in snippet view article find links to article
membrane sarcolemma Biological process biological process regulation of membrane potential heart development skeletal muscle tissue development striated muscle
AKT2 (1,535 words) [view diff] exact match in snippet view article find links to article
cell population proliferation positive regulation of mitochondrial membrane potential negative regulation of apoptotic process carbohydrate metabolic process
Nav1.9 (2,164 words) [view diff] exact match in snippet view article find links to article
transmembrane transport sodium ion transport regulation of postsynaptic membrane potential regulation of sensory perception of pain transport Sources:Amigo /
UCL Neuroscience (1,583 words) [view diff] exact match in snippet view article find links to article
described a statistical analysis of fluctuations they observed in the membrane potential at the frog neuromuscular junction, which were induced by acetylcholine
Pleiotrophin (1,643 words) [view diff] exact match in snippet view article find links to article
to vitamin D learning response to activity negative regulation of membrane potential cerebellum development nervous system development positive regulation
HEBP2 (403 words) [view diff] exact match in snippet view article find links to article
granule lumen Biological process negative regulation of mitochondrial membrane potential positive regulation of necrotic cell death regulation of response
MFN1 (646 words) [view diff] case mismatch in snippet view article find links to article
"Mitochondrial Fusion in Human Cells Is Efficient, Requires the Inner Membrane Potential, and Is Mediated by Mitofusins". Mol. Biol. Cell. 13 (12): 4343–54
T-type calcium channel (2,776 words) [view diff] exact match in snippet view article find links to article
the voltage sensor of the channel opening or closing based on the membrane potential. The exact method by which the S4 segment controls the opening and
Valinomycin (826 words) [view diff] exact match in snippet view article find links to article
Veksler V, Zharkovsky A, Kaasik A (2006). "Loss of mitochondrial membrane potential is associated with increase in mitochondrial volume: physiological
Prestin (1,905 words) [view diff] exact match in snippet view article find links to article
positive regulation of cell motility sulfate transport regulation of membrane potential response to thyroid hormone regulation of intracellular pH chloride
Uncoupling protein (1,604 words) [view diff] exact match in snippet view article find links to article
PMID 11709080. Nicholls DG, Ward MW (April 2000). "Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts".
Vadimezan (603 words) [view diff] exact match in snippet view article find links to article
(STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential". The Journal of Biological Chemistry. 287 (47): 39776–88. doi:10
Dihydrolipoamide dehydrogenase (2,335 words) [view diff] exact match in snippet view article find links to article
mitochondrial acetyl-CoA biosynthetic process from pyruvate regulation of membrane potential aging branched-chain amino acid catabolic process tricarboxylic acid
Lipid emulsion (1,496 words) [view diff] exact match in snippet view article find links to article
matrix into the cytosol. The hydrogen flux disrupts the mitochondrial membrane potential and results in mitochondrial swelling, outer membrane rupture, and
Sib RNA (732 words) [view diff] exact match in snippet view article find links to article
mechanism of ibs protein is not fully understood, but a change in membrane potential upon over-expression of the protein suggests that interactions with
Ussing chamber (559 words) [view diff] exact match in snippet view article find links to article
The basis of membrane potential
WNT1-inducible-signaling pathway protein 3 (625 words) [view diff] exact match in snippet view article find links to article
regulation of signaling receptor activity regulation of mitochondrial membrane potential regulation of reactive oxygen species biosynthetic process Sources:Amigo
Tomatine (2,053 words) [view diff] exact match in snippet view article find links to article
disrupted membrane has an influence on sodium transport, by altering the membrane potential and reducing active sodium transport. When tomatine is orally ingested
BH3 interacting-domain death agonist (1,246 words) [view diff] exact match in snippet view article find links to article
regulation of apoptotic process positive regulation of mitochondrial membrane potential mitochondrial ATP synthesis coupled electron transport negative regulation
Carl Petersen (neuroscientist) (260 words) [view diff] exact match in snippet view article
University. Petersen, Carl (2017). "Whole-cell recording of neuronal membrane potential during behavior". Neuron. 95 (6): 1266–1281. doi:10.1016/j.neuron
Nav1.1 (2,613 words) [view diff] exact match in snippet view article find links to article
action potential propagation neuronal action potential regulation of membrane potential neuromuscular process controlling posture detection of mechanical
Jonathan Ashmore (1,069 words) [view diff] exact match in snippet view article find links to article
S2CID 1950263. Ashmore, J. F.; Meech, R. W. (1986). "Ionic basis of membrane potential in outer hair cells of guinea pig cochlea". Nature. 322 (6077): 368–371
POPDC2 (511 words) [view diff] exact match in snippet view article find links to article
process heart development skeletal muscle tissue development regulation of membrane potential striated muscle cell differentiation Sources:Amigo / QuickGO
Rhodamine 123 (247 words) [view diff] exact match in snippet view article find links to article
Its luminescence quantum yield is 0.90. L. B. Chen. "Mitochondrial membrane potential in living cells."Annu Rev Cell Biol. 4 (1988) 155–181 Darzynkiewicz
HERG (2,551 words) [view diff] exact match in snippet view article find links to article
potential cardiac muscle contraction signal transduction regulation of membrane potential regulation of ion transmembrane transport ventricular cardiac muscle
Isopimaric acid (416 words) [view diff] exact match in snippet view article find links to article
leads to an increased K+-efflux which hyperpolarizes the resting membrane potential, reducing the excitability of the cell in which the BK-channel is
Judith Graham Pool (850 words) [view diff] exact match in snippet view article find links to article
was widely respected in the field of hematology. - Measurements of membrane potential in a single muscle fiber (with Dr. Ralph W. Gerard), 1942 - The coagulation
Nystatin (2,188 words) [view diff] exact match in snippet view article find links to article
serum levels of nystatin are achieved. Nystatin also impacts cell membrane potential and transport by lipid peroxidation. Conjugated double bonds in nystatin's
Hypothalamus (4,695 words) [view diff] exact match in snippet view article find links to article
influence gene expression in particular neurons or induce changes in cell membrane potential and kinase activation, leading to diverse non-genomic cellular functions
Caveolin 3 (2,507 words) [view diff] exact match in snippet view article find links to article
depolarization during cardiac muscle cell action potential regulation of membrane potential muscle organ development regulation of calcium ion import plasma membrane
Osteoclast (2,810 words) [view diff] exact match in snippet view article find links to article
mineral. This includes ruffled border Cl− permeability to control membrane potential and basolateral Cl−/HCO3− exchange to maintain cytosolic pH in physiologically
GRID2 (2,147 words) [view diff] exact match in snippet view article find links to article
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane
STOML2 (710 words) [view diff] exact match in snippet view article find links to article
cardiolipin metabolic process positive regulation of mitochondrial membrane potential T cell receptor signaling pathway interleukin-2 production mitochondrial
GABA transporter type 1 (2,154 words) [view diff] exact match in snippet view article find links to article
offset the positive charge of the Na+ in order to maintain the proper membrane potential. Occluded-out. Once fully loaded, this conformation prevents the release
ABCB5 (1,848 words) [view diff] exact match in snippet view article find links to article
component of plasma membrane membrane Biological process regulation of membrane potential cell differentiation compound eye corneal lens development transmembrane
Aldosterone (3,263 words) [view diff] exact match in snippet view article find links to article
zona glomerulosa cells within adrenal slices spontaneously generate membrane potential oscillations of low periodicity; this innate electrical excitability
Sulfate transporter (2,846 words) [view diff] exact match in snippet view article find links to article
microvillus membrane Biological process ossification regulation of membrane potential regulation of intracellular pH chloride transmembrane transport ion
Metabotropic glutamate receptor (3,645 words) [view diff] exact match in snippet view article find links to article
presynaptic inhibition, and do not appear to affect postsynaptic membrane potential by themselves. Receptors in groups II and III reduce the activity
Palladium (5,943 words) [view diff] exact match in snippet view article find links to article
appear to have a key role in palladium toxicity via mitochondrial membrane potential collapse and depletion of the cellular glutathione (GSH) level. Until
Alpha-actinin-2 (2,571 words) [view diff] exact match in snippet view article find links to article
signaling pathway cardiac muscle cell development regulation of membrane potential platelet degranulation actin filament uncapping MAPK cascade focal
RNF122 (440 words) [view diff] exact match in snippet view article find links to article
polyubiquitination protein ubiquitination negative regulation of mitochondrial membrane potential positive regulation of apoptotic process protein autoubiquitination
Strychnine (4,410 words) [view diff] exact match in snippet view article find links to article
ions into the neuron, causing a hyperpolarization which pushes the membrane potential further from threshold. Strychnine is an antagonist of glycine; it
Circumventricular organs (4,343 words) [view diff] exact match in snippet view article find links to article
it is worthy to note the VOLT neurons typically feature a resting membrane potential in the range of -50 to -67 mV with input resistances ranging from
TCL1A (939 words) [view diff] exact match in snippet view article find links to article
cell population proliferation positive regulation of mitochondrial membrane potential positive regulation of protein oligomerization positive regulation
Glutamate (neurotransmitter) (2,177 words) [view diff] exact match in snippet view article
depolarizing shift in epileptic attacks. This change in the resting membrane potential at seizure foci could cause spontaneous opening of voltage-activated
RIMS2 (828 words) [view diff] exact match in snippet view article find links to article
cAMP-mediated signaling calcium-ion regulated exocytosis regulation of membrane potential calcium ion-regulated exocytosis of neurotransmitter regulation of
FGF14 (876 words) [view diff] exact match in snippet view article find links to article
growth factor receptor signaling pathway regulation of postsynaptic membrane potential signal transduction nervous system development regulation of synaptic
Hepatitis B virus (5,203 words) [view diff] exact match in snippet view article find links to article
of HBx to the mitochondria where HBx decreases the mitochondrial membrane potential. In addition, another HBV protein, HBsAg, also increases ROS through
Coenzyme Q – cytochrome c reductase (2,221 words) [view diff] exact match in snippet view article find links to article
species reacting with oxygen to form superoxide. The effect of high membrane potential is thought to have a similar effect. Superoxide produced at the Qo
Nav1.5 (2,983 words) [view diff] exact match in snippet view article find links to article
determines whether the channel is opened or closed. At the resting membrane potential (around -85 mV), NaV1.5 channels are closed. Upon a stimulus (through
TUSC2 (568 words) [view diff] exact match in snippet view article find links to article
component mitochondrion Biological process regulation of mitochondrial membrane potential cell-cell signaling cell cycle chemokine (C-C motif) ligand 5 production
Quantitative models of the action potential (3,114 words) [view diff] exact match in snippet view article find links to article
PMID 14946714. Hodgkin AL, Huxley AF (1952). "The dual effect of membrane potential on sodium conductance in the giant axon of Loligo". J Physiol. 116
Neural encoding of sound (2,660 words) [view diff] exact match in snippet view article find links to article
particularly potassium, through the open MET channels causes the membrane potential of the hair cell to depolarize. This depolarization opens voltage-gated
Verrucotoxin (601 words) [view diff] exact match in snippet view article find links to article
reversible prolonged action potential duration with zero change in resting membrane potential from ventricular myocytes in guinea pigs.   The second method verrucotoxin
Apamin (1,988 words) [view diff] exact match in snippet view article find links to article
ions out of the cell along their concentration gradient causes the membrane potential to become more negative. The SK channels are present in a wide range
Microfluorimetry (1,123 words) [view diff] exact match in snippet view article find links to article
of neurotoxins on both calcium ion concentration and mitochondrial membrane potential in individual cells. Microfluorimetry can also be used as a method
Salt and cardiovascular disease (3,210 words) [view diff] exact match in snippet view article find links to article
in the blood, extracellular and intracellular fluids, and resting membrane potential. The well known effect of sodium on blood pressure can be explained
PANK2 (gene) (806 words) [view diff] exact match in snippet view article
phosphorylation coenzyme A biosynthetic process regulation of mitochondrial membrane potential aerobic respiration regulation of triglyceride metabolic process regulation
Sodium–potassium pump (3,509 words) [view diff] exact match in snippet view article find links to article
activity and lower force production. In order to maintain the cell membrane potential, cells keep a low concentration of sodium ions and high levels of
STOX1 (114 words) [view diff] exact match in snippet view article find links to article
protein kinase activity cell division regulation of mitochondrial membrane potential positive regulation of gene expression positive regulation of cell
Respiratory complex I (6,480 words) [view diff] exact match in snippet view article find links to article
succinate-supported NAD+ reduction by ubiquinol – in the presence of a high membrane potential, but the exact catalytic mechanism remains unknown. Driving force