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Longer titles found: Subthreshold membrane potential oscillations (view)

searching for Membrane potential 355 found (773 total)

JTV-519 (831 words) [view diff] exact match in snippet view article find links to article

leak, it is able to prevent Ca2+ sparks or increases in the resting membrane potential, which can lead to spontaneous depolarization (cardiac arrhythmias)

UCP2 (1,158 words) [view diff] exact match in snippet view article find links to article

phosphorylation from ATP synthesis by dissipating the mitochondrial membrane potential as heat, also referred to as the mitochondrial proton leak. UCPs facilitate

Cellular neuroscience (1,366 words) [view diff] exact match in snippet view article find links to article

which re-polarizes the membrane potential towards the resting membrane potential. Repolarization of the membrane potential continues, resulting in an

Mitochondrial uncoupling protein 4 (859 words) [view diff] exact match in snippet view article find links to article

inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs

Dendrite (2,775 words) [view diff] exact match in snippet view article find links to article

potential across the neuron's plasma membrane. This change in the membrane potential will passively spread across the dendrite but becomes weaker with

ATP1A3 (1,455 words) [view diff] exact match in snippet view article find links to article

thyroid hormone stimulus regulation of resting membrane potential regulation of presynaptic membrane potential cellular response to amyloid-beta neuron projection

Channel blocker (2,998 words) [view diff] exact match in snippet view article find links to article

the flow of charged ions across the membrane and therefore mediate membrane potential of the cell. Molecules that act as channel blockers are important

KCNK2 (1,421 words) [view diff] exact match in snippet view article find links to article

channel that releases potassium out of the cell to control resting membrane potential. The channel is opened by anionic lipid, certain anesthetics, membrane

Cromakalim (361 words) [view diff] exact match in snippet view article find links to article

pressure. Hyperpolarisation of smooth muscle cell membranes pulls their membrane potential away from the threshold, so making it more difficult to excite them

CLIC1 (1,193 words) [view diff] exact match in snippet view article find links to article

regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation

GRIK3 (657 words) [view diff] exact match in snippet view article find links to article

regulation of presynaptic membrane potential transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component

Inward-rectifier potassium channel (1,973 words) [view diff] exact match in snippet view article find links to article

regulating neuronal activity, by helping to stabilize the resting membrane potential of the cell. By convention, inward current (positive charge moving

GABRR1 (943 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process regulation of postsynaptic membrane potential regulation of presynaptic membrane potential Sources:Amigo

Cyclic nucleotide-gated channel alpha 1 (1,216 words) [view diff] exact match in snippet view article find links to article

closure of CNGA1/B1 channels and, therefore, hyperpolarization of the membrane potential. Cyclic nucleotide-gated ion channel GRCh38: Ensembl release 89: ENSG00000198515

Azimilide (953 words) [view diff] exact match in snippet view article find links to article

depolarization. They shift the threshold towards zero or hyperpolarize the membrane potential. Although each agent has its own properties and will have thus a different

CLIC2 (689 words) [view diff] exact match in snippet view article find links to article

regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation

TECTA (841 words) [view diff] exact match in snippet view article find links to article

deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one

ADP/ATP translocase 4 (1,607 words) [view diff] exact match in snippet view article find links to article

ADP/ATP exchange across the mitochondrial membranes and regulating membrane potential. In particular, ANT4 is essential to spermatogenesis, as it imports

CHRNA10 (326 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic

Excitatory synapse (2,550 words) [view diff] exact match in snippet view article find links to article

of that cell. Depolarization, a deviation from a neuron's resting membrane potential towards its threshold potential, increases the likelihood of an action

Kv1.1 (2,125 words) [view diff] exact match in snippet view article find links to article

regulation of presynaptic membrane potential voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component

Myometrium (630 words) [view diff] exact match in snippet view article find links to article

resting membrane potential (Vrest) of uterine smooth muscle has been recorded to be between -35 and -80 mV. As with the resting membrane potential of other

CLIC4 (1,164 words) [view diff] exact match in snippet view article find links to article

regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation

Voltage-gated proton channel (802 words) [view diff] exact match in snippet view article find links to article

hydrogen channels usually hyperpolarize the cell membrane, or makes the membrane potential more negative. A recent discovery has shown that the voltage-gated

GLRA2 (488 words) [view diff] exact match in snippet view article find links to article

transmission regulation of membrane potential response to amino acid nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO

GABRG3 (589 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

GABRR2 (609 words) [view diff] exact match in snippet view article find links to article

transmembrane transport regulation of membrane potential nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO

Brodmann area 49 (344 words) [view diff] exact match in snippet view article find links to article

are modulated by local theta rhythm, and display theta-frequency membrane potential oscillations (Glasgow & Chapman, 2007; Taube, 1995). Furthermore,

Brain mitochondrial carrier protein 1 (758 words) [view diff] exact match in snippet view article find links to article

inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs

Zona glomerulosa (712 words) [view diff] exact match in snippet view article find links to article

zona glomerulosa cells within adrenal slices spontaneously generate membrane potential oscillations of low periodicity; this innate electrical excitability

Voltage-dependent anion channel (1,698 words) [view diff] exact match in snippet view article find links to article

molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30–40 mV. VDAC facilitates

GLRB (546 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component cytoplasm integral component of membrane postsynaptic

Andersen–Tawil syndrome (2,389 words) [view diff] exact match in snippet view article find links to article

current known as IK1 which is responsible for setting the resting membrane potential of muscle cells and is therefore critical for maintaining the normal

CHRND (744 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane

Goldman equation (2,114 words) [view diff] exact match in snippet view article find links to article

charge determines the sign of the membrane potential contribution. During an action potential, although the membrane potential changes about 100mV, the concentrations

CHRNB1 (673 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane acetylcholine-gated

HCN channel (1,554 words) [view diff] exact match in snippet view article find links to article

and K+, and are constitutively open at voltages near the resting membrane potential. HCN channels are encoded by four genes (HCN1, 2, 3, 4) and are widely

GABRG1 (896 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

Group C nerve fiber (2,563 words) [view diff] exact match in snippet view article find links to article

membrane potential of unmyelinated axons like C fibers. Moalem-Taylor et al. experimentally used chemical modulators with known effects on membrane potential

Bcl-2-associated X protein (2,112 words) [view diff] exact match in snippet view article find links to article

voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated

CHRNB4 (984 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component

KCNH8 (331 words) [view diff] exact match in snippet view article find links to article

S2CID 219195192. Baxter DF, Kirk M, Garcia AF, et al. (2002). "A novel membrane potential-sensitive fluorescent dye improves cell-based assays for ion channels"

GABRE (762 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

Hyperkalemic periodic paralysis (1,073 words) [view diff] exact match in snippet view article find links to article

original resting membrane potential. In the presence of hyperkalemia, which causes an additional chronic depolarization of the membrane potential, this sodium

GABRB1 (1,100 words) [view diff] exact match in snippet view article find links to article

chemical synaptic transmission regulation of membrane potential nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO

Molecular neuroscience (3,050 words) [view diff] exact match in snippet view article find links to article

ions into a neuron, resulting in a depolarization from the resting membrane potential of a neuron to lead to a graded potential or action potential, depending

CHRNB2 (1,060 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component

CHRNB2 (1,060 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component acetylcholine-gated channel complex integral component

Synaptic potential (1,541 words) [view diff] exact match in snippet view article find links to article

EPSPs to both depolarize the postsynaptic membrane from its resting membrane potential to its threshold and counterbalance the concurrent IPSPs that hyperpolarize

CHRNA9 (745 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component synapse integral component of membrane cell junction

CHRNA1 (1,173 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane membrane synapse

Soliton model in neuroscience (3,686 words) [view diff] exact match in snippet view article find links to article

ions to enter the cell (inward current). The resulting decrease in membrane potential opens nearby voltage-gated sodium channels, thus propagating the action

Stimulus (physiology) (3,935 words) [view diff] exact match in snippet view article

permeable to chloride ions, making the membrane potential of the cell negative; a negative membrane potential makes it more difficult for the cell to

CHRNE (1,339 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane

Gamma-aminobutyric acid receptor subunit gamma-2 (1,397 words) [view diff] exact match in snippet view article find links to article

signal transduction regulation of membrane potential nervous system process regulation of postsynaptic membrane potential inhibitory synapse assembly Sources:Amigo

GABRD (1,583 words) [view diff] exact match in snippet view article find links to article

transmission signal transduction regulation of membrane potential nervous system process regulation of postsynaptic membrane potential Sources:Amigo / QuickGO

Melainabacteria (477 words) [view diff] exact match in snippet view article find links to article

electron transport chains but have multiple methods to generate a membrane potential which can then produce ATP via ATP synthase. They are able to use

Bcl-2 homologous antagonist killer (2,595 words) [view diff] exact match in snippet view article find links to article

mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with

GABRA5 (1,057 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

KCNC2 (597 words) [view diff] exact match in snippet view article find links to article

voltage-gated ion channel activity involved in regulation of presynaptic membrane potential Cellular component integral component of membrane vesicle perikaryon

Uterine contraction (1,071 words) [view diff] exact match in snippet view article find links to article

resting membrane potential (Vrest) of uterine smooth muscle has been recorded to be between −35 and −80 mV. As with the resting membrane potential of other

GABRA6 (897 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

GABRA4 (738 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

Halorhodopsin (737 words) [view diff] exact match in snippet view article find links to article

green/yellow light to move chloride ions into the cell, overcoming the membrane potential. Beside chlorides it transports other halides and nitrates into the

GRID1 (720 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane cell junction postsynaptic

Morris–Lecar model (992 words) [view diff] exact match in snippet view article find links to article

hyperpolarizing current is carried by K+. Activation gates follow changes in membrane potential sufficiently rapidly that the activating conductance can instantaneously

KCNK6 (723 words) [view diff] exact match in snippet view article find links to article

component of plasma membrane Biological process regulation of resting membrane potential potassium ion transport regulation of ion transmembrane transport

Protonophore (487 words) [view diff] exact match in snippet view article find links to article

Protonophores uncouple oxidative phosphorylation via a decrease in the membrane potential of the inner membrane of mitochondria. They stimulate mitochondria

Mechanotransduction (3,069 words) [view diff] exact match in snippet view article find links to article

channels to open and produce a transduction current that changes the membrane potential of the cell. Typically the mechanical stimulus gets filtered in the

Gamma-aminobutyric acid receptor subunit alpha-1 (1,035 words) [view diff] exact match in snippet view article find links to article

postsynaptic membrane potential ion transmembrane transport signal transduction chemical synaptic transmission regulation of membrane potential nervous system

CHRNB3 (746 words) [view diff] exact match in snippet view article find links to article

synaptic transmission signal transduction regulation of postsynaptic membrane potential excitatory postsynaptic potential cation transmembrane transport ion

Synaptic gating (3,246 words) [view diff] exact match in snippet view article find links to article

hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred

Summation (neurophysiology) (2,291 words) [view diff] exact match in snippet view article

postsynaptic neuron. As long as the membrane potential is below threshold for firing impulses, the membrane potential can summate inputs. That is, if the

GABBR1 (1,220 words) [view diff] exact match in snippet view article find links to article

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Cellular component cytoplasm integral component of membrane G protein-coupled

KCNK1 (795 words) [view diff] exact match in snippet view article find links to article

conduction potassium ion transmembrane transport regulation of resting membrane potential stabilization of membrane potential Sources:Amigo / QuickGO

Diastolic depolarization (338 words) [view diff] exact match in snippet view article find links to article

action. The amount of net inward current required to move the cell membrane potential during the pacemaker phase is extremely small, in the order of few

Prostomatea (135 words) [view diff] exact match in snippet view article find links to article

00290.x. PMID 18070326. Rudberg P, Sand O (February 2000). "Bistable membrane potential of the ciliate Coleps hirtus". The Journal of Experimental Biology

Parasubiculum (349 words) [view diff] exact match in snippet view article find links to article

are modulated by local theta rhythm, and display theta-frequency membrane potential oscillations (Glasgow & Chapman, 2007; Taube, 1995). Furthermore,

Synaptosome (929 words) [view diff] exact match in snippet view article find links to article

have become a common tool for drug testing. They maintain a normal membrane potential, contain presynaptic receptors, translocate metabolites and ions,

CHRNA5 (905 words) [view diff] exact match in snippet view article find links to article

postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport regulation of synaptic vesicle exocytosis regulation of membrane potential

SLC8B1 (325 words) [view diff] exact match in snippet view article find links to article

antiporter activity involved in regulation of cardiac muscle cell membrane potential Cellular component integral component of membrane membrane plasma

PINK1 (2,687 words) [view diff] exact match in snippet view article find links to article

membrane potential. Mitochondria with a strong, healthy membrane potential were more likely to undergo fusion than mitochondria with a low membrane potential

Mitochondrial membrane transport protein (3,403 words) [view diff] exact match in snippet view article find links to article

restricts the movement of all molecules. The two membranes also vary in membrane potential and pH. These factors play a role in the function of mitochondrial

Carbonyl cyanide m-chlorophenyl hydrazone (499 words) [view diff] exact match in snippet view article find links to article

A. Holoubek; K. Sigler (1999). "Factors and processes involved in membrane potential build-up in yeast: diS-C3(3) assay". The International Journal of

CHRNA2 (864 words) [view diff] exact match in snippet view article find links to article

postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport chemical synaptic transmission regulation of membrane potential nervous

Catasetum fimbriatum (434 words) [view diff] exact match in snippet view article find links to article

flower this stimulates the antennae triggering a quick change in membrane potential. This propagates an action potential that results in an increase in

LTP induction (1,102 words) [view diff] exact match in snippet view article find links to article

roughly equal, so when this channel is open the resulting change in membrane potential tends towards zero (a bit more than halfway between the equilibrium

GRIN3A (1,017 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component synapse integral component of membrane NMDA selective

GRIK5 (825 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic

GRIN2C (1,125 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane

KCNJ10 (1,321 words) [view diff] exact match in snippet view article find links to article

synaptic plasticity central nervous system myelination regulation of membrane potential regulation of ion transmembrane transport ion transport potassium

GRIK2 (3,056 words) [view diff] exact match in snippet view article find links to article

regulation of presynaptic membrane potential transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component

Avoidance reaction (206 words) [view diff] exact match in snippet view article find links to article

potentials. The simplest explanation for the avoidance reaction is that membrane potential controls the influx of calcium ions, which regulates the beat frequency

Neural backpropagation (2,261 words) [view diff] exact match in snippet view article find links to article

channels and are transmembrane channels that help maintain the cell's membrane potential (Cai 2007). Typically, they play a crucial role in returning the cell

Spontaneous potential (1,163 words) [view diff] exact match in snippet view article find links to article

(EC) is the sum of liquid junction or diffusion potential (EJ), and membrane potential (EM) Liquid junction potential is established at the direct contact

Proguanil (1,029 words) [view diff] exact match in snippet view article find links to article

cascade. This is commonly referred to as "collapse of the mitochondrial membrane potential." Proguanil lowers the effective concentration of atovaquone needed

KCNE3 (3,022 words) [view diff] exact match in snippet view article find links to article

unless the cell is held at a strongly hyperpolarizing (negative) membrane potential. The ability of KCNQ1-KCNE3 channels to remain open at weakly negative

HTR3D (192 words) [view diff] exact match in snippet view article find links to article

transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

CHRNA6 (952 words) [view diff] exact match in snippet view article find links to article

transduction chemical synaptic transmission regulation of postsynaptic membrane potential excitatory postsynaptic potential cation transmembrane transport ion

UCP3 (1,932 words) [view diff] exact match in snippet view article find links to article

synthesis of ATP, and dissipating energy stored in the mitochondrial membrane potential as heat. Uncoupling proteins also reduce generation of reactive oxygen

KCNC1 (1,183 words) [view diff] exact match in snippet view article find links to article

voltage-gated ion channel activity involved in regulation of presynaptic membrane potential Cellular component integral component of membrane membrane voltage-gated

KCND2 (1,211 words) [view diff] exact match in snippet view article find links to article

voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic

SLC26A8 (418 words) [view diff] exact match in snippet view article find links to article

differentiation oxalate transport sulfate transport regulation of membrane potential regulation of intracellular pH ion transport anion transport multicellular

Kir2.6 (143 words) [view diff] exact match in snippet view article find links to article

Inwardly rectifying potassium channels, such as Kir2.6, maintain resting membrane potential in excitable cells and aid in repolarization of cells following depolarization

GABRA3 (2,246 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential Sources:Amigo /

GRIA1 (1,356 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential amyloid-beta binding signaling receptor activity Cellular component

Aconitine (3,360 words) [view diff] exact match in snippet view article find links to article

the membrane potential causes the opening (activation) of potassium channels and potassium efflux, which results in repolarization of the membrane potential

Atovaquone/proguanil (939 words) [view diff] exact match in snippet view article find links to article

parasitic electron transport chain, collapsing the mitochondrial membrane potential. The malarial electron transport chain does not contribute significantly

Intermembrane space (1,064 words) [view diff] exact match in snippet view article find links to article

voltage gradient (membrane potential). The pH in the IMS is about 0.7 unit lower than the one in the matrix and the membrane potential of the IMS side becomes

Glycine receptor, alpha 1 (1,165 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane perikaryon postsynaptic

HTR3C (275 words) [view diff] exact match in snippet view article find links to article

transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

KCNK4 (1,740 words) [view diff] exact match in snippet view article find links to article

TRAAK channels play a critical role in the maintenance of the resting membrane potential in excitable cell types. More recently, TRAAK channels have been identified

GABRA2 (1,826 words) [view diff] exact match in snippet view article find links to article

regulation of membrane potential nervous system process synaptic transmission, GABAergic regulation of postsynaptic membrane potential inhibitory synapse

Exponential integrate-and-fire (1,467 words) [view diff] exact match in snippet view article find links to article

where V {\displaystyle V} is the membrane potential, V T {\displaystyle V_{T}} is the intrinsic membrane potential threshold, τ m {\displaystyle \tau

Electrical tuning (394 words) [view diff] exact match in snippet view article find links to article

increases, but then with the exit of the K+ the cell overshoots the membrane potential and hyperpolarizes. Different cells have different delays for K+ leaving

Inner mitochondrial membrane (936 words) [view diff] exact match in snippet view article find links to article

protein MIC60/Mic60 (formerly Mitofilin/Fcj1) leads to a reduced inner membrane potential and impaired growth and to dramatically aberrant inner membrane structures

Halcurin (581 words) [view diff] exact match in snippet view article find links to article

the extracellular site 3 on the voltage gated sodium channels in a membrane potential-dependent manner. The polypeptide toxin halcurin is named after its

CHRNA7 (1,547 words) [view diff] exact match in snippet view article find links to article

factor production response to nicotine regulation of postsynaptic membrane potential excitatory postsynaptic potential positive regulation of protein phosphorylation

HTR3E (320 words) [view diff] exact match in snippet view article find links to article

transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

GRIN1 (1,045 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential amyloid-beta binding glutamate-gated calcium ion channel activity

Transmembrane channels (555 words) [view diff] exact match in snippet view article find links to article

is the gated channel which requires a trigger, such as a change in membrane potential in voltage-gated channels, to unlock or lock the pore opening. Voltage-gated

Mitochondrial matrix (1,865 words) [view diff] exact match in snippet view article find links to article

the concentration of ions such as Ca2+ driven by the mitochondrial membrane potential. The membrane only allows nonpolar molecules such as CO2 and O2 and

Cardiolipin (3,390 words) [view diff] exact match in snippet view article find links to article

indicator of CL content in mitochondria. However, NAO is influenced by membrane potential and/or the spatial arrangement of CL, so it's not proper to use NAO

Purkinje cell (3,114 words) [view diff] exact match in snippet view article find links to article

"Purkinje cells in awake behaving animals operate at the up state membrane potential". Nature Neuroscience. 9 (4): 459–461. doi:10.1038/nn0406-459. PMID 16568098

GRIK1 (1,654 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane cell junction plasma

Beta-1 adrenergic receptor (1,704 words) [view diff] exact match in snippet view article find links to article

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane endosome membrane

Γ-Aminobutyric acid (5,251 words) [view diff] exact match in snippet view article find links to article

cell's membrane less negative), shunting (has no effect on the cell's membrane potential), or inhibitory/hyperpolarizing (makes the cell's membrane more negative)

KCNT2 (263 words) [view diff] exact match in snippet view article find links to article

transmembrane transport potassium ion transport ion transport regulation of membrane potential potassium ion export across plasma membrane Sources:Amigo / QuickGO

KCNH3 (304 words) [view diff] exact match in snippet view article find links to article

transduction regulation of ion transmembrane transport regulation of membrane potential potassium ion transmembrane transport potassium ion transport ion

Zinc-activated ion channel (211 words) [view diff] exact match in snippet view article find links to article

transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

KCNH6 (363 words) [view diff] exact match in snippet view article find links to article

integral component of plasma membrane Biological process regulation of membrane potential potassium ion transport regulation of ion transmembrane transport

Lq2 (627 words) [view diff] exact match in snippet view article find links to article

ROMK1. This ion channel contributes to the regulation of the resting membrane potential. Since all potassium channels share the same ion conducting outer

KCNH4 (247 words) [view diff] exact match in snippet view article find links to article

transport potassium ion transport regulation of ion transmembrane transport transmembrane transport regulation of membrane potential Sources:Amigo / QuickGO

Sodium–hydrogen antiporter 1 (1,435 words) [view diff] exact match in snippet view article find links to article

antiporter activity involved in regulation of cardiac muscle cell membrane potential calmodulin binding GO:0001948 protein binding GO:0032947 molecular

Celivarone (1,221 words) [view diff] exact match in snippet view article find links to article

flow affect the heart's ability to contract by altering the resting membrane potential, affecting the cell's ability to conduct or transmit an action potential

Metabotropic glutamate receptor 1 (2,213 words) [view diff] exact match in snippet view article find links to article

protein-coupled receptor activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane G protein-coupled

Spike response model (3,722 words) [view diff] exact match in snippet view article find links to article

{\displaystyle \eta } of the model can be interpreted as the response of the membrane potential to an incoming spike (response kernel ε {\displaystyle \varepsilon

GRIA3 (2,070 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane endocytic vesicle

GABRR3 (401 words) [view diff] exact match in snippet view article find links to article

synaptic transmission ion transmembrane transport signal transduction regulation of membrane potential nervous system process Sources:Amigo / QuickGO

Muscle fatigue (2,030 words) [view diff] exact match in snippet view article find links to article

potentials. The shift in K+ changes the membrane potential around the muscle fiber. The change in membrane potential causes a decrease in the release of calcium

KCNK12 (428 words) [view diff] exact match in snippet view article find links to article

regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

KCNT1 (364 words) [view diff] exact match in snippet view article find links to article

Biological process potassium ion transport ion transport potassium ion transmembrane transport regulation of membrane potential Sources:Amigo / QuickGO

KCNK13 (453 words) [view diff] exact match in snippet view article find links to article

regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

KCNK16 (390 words) [view diff] exact match in snippet view article find links to article

regulation of ion transmembrane transport ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO

KCNH7 (448 words) [view diff] exact match in snippet view article find links to article

ion transmembrane transport potassium ion transport regulation of membrane potential regulation of ion transmembrane transport Sources:Amigo / QuickGO

GRIN2A (2,079 words) [view diff] exact match in snippet view article find links to article

of protein catabolic process response to amphetamine regulation of membrane potential directional locomotion modulation of chemical synaptic transmission

GLRA3 (438 words) [view diff] exact match in snippet view article find links to article

transmembrane transport signal transduction chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

Prajmaline (819 words) [view diff] exact match in snippet view article find links to article

Na-K-ATPase pump inhibition, chemical anoxia, and glycolytic blockade on membrane potential of rat optic nerve". Brain Research. 1037 (1–2): 171–9. doi:10.1016/j

KCNK7 (486 words) [view diff] exact match in snippet view article find links to article

regulation of ion transmembrane transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

HCN3 (523 words) [view diff] exact match in snippet view article find links to article

sodium ion transport cellular response to dopamine regulation of membrane potential regulation of ion transmembrane transport ion transport potassium

The Hallmarks of Cancer (2,491 words) [view diff] exact match in snippet view article find links to article

likely contributes to the deactivation of mitochondria. Mitochondrial membrane potential is hyperpolarized to prevent voltage-sensitive permeability transition

KCNK17 (451 words) [view diff] exact match in snippet view article find links to article

regulation of ion transmembrane transport ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO

KCNK10 (534 words) [view diff] exact match in snippet view article find links to article

transmembrane transport memory ion transport signal transduction stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

Hypokalemia (3,510 words) [view diff] exact match in snippet view article find links to article

the resting membrane potential. This hyperpolarization is caused by the effect of the altered potassium gradient on resting membrane potential as defined

Dinoseb (1,982 words) [view diff] exact match in snippet view article find links to article

words: The proton gradient is lower, so the membrane potential will be lower. As the membrane potential is the driving force for the production of ATP

Neurotensin receptor 2 (656 words) [view diff] exact match in snippet view article find links to article

component of plasma membrane membrane Biological process regulation of membrane potential phospholipase C-activating G protein-coupled receptor signaling pathway

Forskolin (724 words) [view diff] exact match in snippet view article find links to article

regulation of Bcl-2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release". Cell Biology International. 30 (11): 940–6

Translocase of the inner membrane (944 words) [view diff] exact match in snippet view article find links to article

inner mitochondrial membrane in a potential-dependent fashion. The membrane potential is necessary for both insertion of the precursor into the carrier

Denervation (1,641 words) [view diff] exact match in snippet view article find links to article

electrical induction in denervated muscles. Changes in the resting membrane potential involving denervated muscles presents mild depolarization when a muscle

Muscarinic acetylcholine receptor M1 (2,066 words) [view diff] exact match in snippet view article find links to article

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential G protein-coupled serotonin receptor activity neurotransmitter receptor

Cyclic nucleotide-gated channel alpha 4 (415 words) [view diff] exact match in snippet view article find links to article

of smell ion transport ion transmembrane transport regulation of membrane potential potassium ion transmembrane transport cation transmembrane transport

GABRP (550 words) [view diff] exact match in snippet view article find links to article

transduction chloride transmembrane transport chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

Cyclic nucleotide-gated channel alpha 2 (533 words) [view diff] exact match in snippet view article find links to article

plasma membrane Biological process response to stimulus regulation of membrane potential ion transport sensory perception of smell ion transmembrane transport

CNGB1 (627 words) [view diff] exact match in snippet view article find links to article

regulation of rhodopsin mediated signaling pathway regulation of membrane potential cation transport ion transport photoreceptor cell outer segment organization

KCNK15 (481 words) [view diff] exact match in snippet view article find links to article

transmembrane transport cardiac conduction ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

KCNU1 (529 words) [view diff] exact match in snippet view article find links to article

transmembrane transport potassium ion transmembrane transport sperm-egg recognition reproductive process regulation of membrane potential Sources:Amigo / QuickGO

KIF5B (1,013 words) [view diff] exact match in snippet view article find links to article

microtubule positive regulation of potassium ion transport regulation of membrane potential positive regulation of synaptic transmission, GABAergic axon guidance

Variation potential (686 words) [view diff] exact match in snippet view article find links to article

potential, like an action potential, is a temporary change in the membrane potential of the plant cell by depolarization and consequent repolarization

KCNK18 (540 words) [view diff] exact match in snippet view article find links to article

transport potassium ion transmembrane transport stabilization of membrane potential potassium ion export across plasma membrane Sources:Amigo / QuickGO

Nervous system network models (5,144 words) [view diff] exact match in snippet view article find links to article

extensively used and is based on two generic models, one of cell membrane potential Goldman (1943) and Hodgkin and Katz (1949), and the other based on

BmKAEP (752 words) [view diff] exact match in snippet view article find links to article

Subsequently, the sodium current amplitude decreases, due to the membrane potential depolarization, thus suppressing action potentials. BmK venom induces

Matteo Carandini (794 words) [view diff] exact match in snippet view article find links to article

the relationship between synaptic excitation, synaptic inhibition, membrane potential, and firing rate in visual cortex and discovered that prolonged visual

Electroporation (5,021 words) [view diff] exact match in snippet view article find links to article

field, a large membrane potential at the two pole of a cell can be created. In the 1970s it was discovered that when a membrane potential reached a critical

Lorcainide (1,015 words) [view diff] exact match in snippet view article find links to article

found in high concentrations in the ventricular myocytes, open at a membrane potential of −80 mv in typical cardiac rhythm. This will result in a rapid upstroke

Guillardia (456 words) [view diff] exact match in snippet view article find links to article

channelrhodopsins were isolated from Guillardia theta that hyperpolarize neuronal membrane potential and are potent inhibitors of neural activity. Bruce A. Curtis; Goro

Spike potential (211 words) [view diff] exact match in snippet view article find links to article

resting membrane potential of the gastrointestinal smooth muscle becomes more positive than about -40 millivolts (the normal resting membrane potential in

SLC25A39 (522 words) [view diff] exact match in snippet view article find links to article

"Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial

Pyrazinamide (2,317 words) [view diff] exact match in snippet view article find links to article

The accumulation of pyrazinoic acid was also suggested to disrupt membrane potential and interfere with energy production, necessary for survival of M

CACNA1G (436 words) [view diff] exact match in snippet view article find links to article

depolarization during action potential calcium ion import regulation of membrane potential regulation of ion transmembrane transport regulation of atrial cardiac

GLRX (884 words) [view diff] exact match in snippet view article find links to article

nucleobase-containing small molecule interconversion positive regulation of membrane potential protein deglutathionylation cell redox homeostasis electron transport

KCNK5 (626 words) [view diff] exact match in snippet view article find links to article

ion transmembrane transport excretion ion transport potassium ion transmembrane transport stabilization of membrane potential Sources:Amigo / QuickGO

GABRQ (673 words) [view diff] exact match in snippet view article find links to article

neurotransmitter transport ion transmembrane transport chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

Muscle contraction (7,093 words) [view diff] exact match in snippet view article find links to article

quickly jumps from the resting membrane potential of -90mV to as high as +75mV as sodium enters. The membrane potential then becomes hyperpolarized when

Sodium-calcium exchanger (2,216 words) [view diff] exact match in snippet view article find links to article

cardiac arrhythmia. Since the transport is electrogenic (alters the membrane potential), depolarization of the membrane can reverse the exchanger's direction

KCNH5 (535 words) [view diff] exact match in snippet view article find links to article

transition of mitotic cell cycle signal transduction regulation of membrane potential regulation of ion transmembrane transport ion transport potassium

Ischemic cell death (1,093 words) [view diff] exact match in snippet view article find links to article

increase in UCP-2 levels leads to a rapid decrease in mitochondrial membrane potential, reducing mitochondrial NADH and intracellular ATP levels, initiating

Veratridine (1,207 words) [view diff] exact match in snippet view article find links to article

turning the membrane potential to a more positive one and also modifies the effect of progesterone on [Ca2+]i and sperm membrane potential. The activation

Cardiac physiology (5,774 words) [view diff] exact match in snippet view article find links to article

that allow a normal and slow influx of sodium ions that causes the membrane potential to rise slowly from an initial value of −60 mV up to about –40 mV

Anion exchange transporter (536 words) [view diff] exact match in snippet view article find links to article

transport sulfate transport gastric acid secretion regulation of membrane potential regulation of intracellular pH ion transport anion transport bicarbonate

Brian M. Salzberg (2,137 words) [view diff] exact match in snippet view article find links to article

colleagues, they established what would be the first link between membrane potential and second messenger activation. Other contributions include the first

Metabotropic glutamate receptor 5 (3,215 words) [view diff] exact match in snippet view article find links to article

protein-coupled receptor activity involved in regulation of postsynaptic membrane potential neurotransmitter receptor activity involved in regulation of postsynaptic

BRL-32872 (812 words) [view diff] exact match in snippet view article find links to article

orally or via intravenous injection, and has no effect on resting membrane potential. The effects BRL-32872 have been well documented in animal models

Adenosine triphosphate (4,756 words) [view diff] exact match in snippet view article find links to article

glycolytic rates and ATP hydrolysis), contributes to mitochondrial membrane potential and directly drives ATP synthesis. Most of the ATP synthesized in

Sodium-dependent phosphate transport protein 2A (340 words) [view diff] exact match in snippet view article find links to article

regulation of sodium-dependent phosphate transport positive regulation of membrane potential protein homooligomerization cellular phosphate ion homeostasis sodium

ATP1A4 (934 words) [view diff] exact match in snippet view article find links to article

transmembrane electrochemical gradient sodium ion transport regulation of membrane potential ion transport potassium ion transport regulation of cellular pH spermatogenesis

Philip A. Gale (1,573 words) [view diff] exact match in snippet view article find links to article

and the development of anion transporters that can be switched by membrane potential gradients or by the presence of reducing agents found in higher concentrations

HTR3B (1,020 words) [view diff] exact match in snippet view article find links to article

transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

Hair cell (3,453 words) [view diff] exact match in snippet view article find links to article

neurotransmitter release in response to a change of as little as 100 μV in membrane potential. Hair cells are also able to distinguish tones through one of two

PYCR1 (594 words) [view diff] exact match in snippet view article find links to article

matrix mitochondrion Biological process regulation of mitochondrial membrane potential cellular response to oxidative stress negative regulation of hydrogen

Slow-wave potential (1,150 words) [view diff] exact match in snippet view article find links to article

velocities in the stomach due to the existence of a gradient of resting membrane potential gradient, interstitial cells of Cajal distributions, and gastric wall

Ralph W. Gerard (1,283 words) [view diff] exact match in snippet view article find links to article

Biochem J., 23, pp. 738–47 (1929) G. Ling & R.W. Gerard, The normal membrane potential of frog sartorius fibers, in: J. Cell. Comp. Physiol., 34, pp. 383–96

Ajmaline (918 words) [view diff] exact match in snippet view article find links to article

refractory period), and therefore makes it take more time for the membrane potential to get below the threshold level so the action potential can be re-fired

Steady state (biochemistry) (1,421 words) [view diff] exact match in snippet view article

ions move across the cell membrane such that a constant resting membrane potential is achieved; this is ionic steady state. In the pump-leak model of

Mary Helen Goldsmith (901 words) [view diff] exact match in snippet view article find links to article

during transport of polar chemicals, intracellular measurements of membrane potential, and activation of potassium channels. Goldsmith, M H M (June 1977)

Cyclic nucleotide gated channel beta 3 (818 words) [view diff] exact match in snippet view article find links to article

integral component of plasma membrane Biological process regulation of membrane potential cation transport ion transport cation transmembrane transport signal

KCNS3 (781 words) [view diff] exact match in snippet view article find links to article

main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The

Polarized membrane (159 words) [view diff] case mismatch in snippet view article find links to article

00003-8. ISBN 978-0-12-388425-1. McCormick, David A. (2014). "Membrane Potential and Action Potential". From Molecules to Networks. Elsevier. pp. 351–376

Saltatory conduction (672 words) [view diff] exact match in snippet view article find links to article

Goldman equation – Generalization of the Nernst equation for the membrane potential Hindmarsh–Rose model – Of the spiking-bursting behavior of a neuron

Transcellular transport (697 words) [view diff] exact match in snippet view article find links to article

David R. (2012). "Plasma membrane. membrane transport, and resting membrane potential". Medical physiology : principles for clinical medicine (4th ed.,

Georg Nagel (981 words) [view diff] exact match in snippet view article find links to article

illumination with blue light caused a strong depolarization of the membrane potential. Following this proof-of-principle publication, ChR2 was expressed

Douglas G. McMahon (2,212 words) [view diff] exact match in snippet view article find links to article

molluscan eye exhibited circadian rhythms in spike frequency and membrane potential, indicating they are the clock neurons. He became the 1986 winner

Excitatory amino acid transporter 4 (563 words) [view diff] exact match in snippet view article find links to article

membrane Biological process chemical synaptic transmission regulation of membrane potential ion transport glutamate secretion aspartate transmembrane transport

Sulfonylurea receptor (646 words) [view diff] exact match in snippet view article find links to article

on the tissue in which the KATP channel is expressed, altering the membrane potential can trigger a variety of downstream events. For example, in pancreatic

Maddika Subba Reddy (786 words) [view diff] exact match in snippet view article find links to article

independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent

Manganese(II) chloride (755 words) [view diff] exact match in snippet view article

Characterization of size distribution, trapped volume and ability to maintain a membrane potential" (PDF), Biochimica et Biophysica Acta (BBA) - Biomembranes, 812 (1):

Transcranial direct-current stimulation (5,730 words) [view diff] exact match in snippet view article find links to article

changes brain function is either by causing the neuron’s resting membrane potential to depolarize or hyperpolarize. When positive stimulation (anodal

CHRNA3 (1,037 words) [view diff] exact match in snippet view article find links to article

locomotory behavior regulation of smooth muscle contraction regulation of membrane potential regulation of acetylcholine secretion, neurotransmission synaptic

Cyclic nucleotide-gated channel alpha 3 (968 words) [view diff] exact match in snippet view article find links to article

projection Biological process response to stimulus regulation of membrane potential cation transport response to magnesium ion ion transport ion transmembrane

TRPM4 (454 words) [view diff] exact match in snippet view article find links to article

positive regulation of canonical Wnt signaling pathway regulation of membrane potential cation transport ion transport protein sumoylation dendritic cell

KCNN4 (1,297 words) [view diff] exact match in snippet view article find links to article

process defense response phospholipid translocation stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

HCN2 (1,094 words) [view diff] exact match in snippet view article find links to article

transport sodium ion transport cell-cell signaling regulation of membrane potential regulation of ion transmembrane transport ion transport potassium

CACNG2 (1,204 words) [view diff] exact match in snippet view article find links to article

membrane hyperpolarization transmission of nerve impulse regulation of membrane potential regulation of ion transmembrane transport membrane depolarization

KCNK3 (1,047 words) [view diff] exact match in snippet view article find links to article

ion concentration chemical synaptic transmission stabilization of membrane potential regulation of signaling receptor activity Sources:Amigo / QuickGO

H1 neuron (1,654 words) [view diff] exact match in snippet view article find links to article

increasing the dynamic range over which H1 operates. Changes in H1 axonal membrane potential is proportional to the amplitude of optic image velocity. However

GABRB3 (3,080 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane

ASIC2 (984 words) [view diff] exact match in snippet view article find links to article

involved in sensory perception sodium ion transport regulation of membrane potential regulation of ion transmembrane transport response to mechanical stimulus

CLCNKA (1,284 words) [view diff] exact match in snippet view article find links to article

thin and thick ascending limb of the nephrons. Experimentally, the membrane potential at which the channels show no net movement of ions at a given chloride

Decynium-22 (759 words) [view diff] exact match in snippet view article find links to article

Kucheryavykh L, Sanabria P, Jiménez-Rivera C, Struganova I, et al. (2010). "Membrane potential and pH-dependent accumulation of decynium-22 (1,1′-diethyl-2,2′-cyanine

Histrionicotoxins (1,487 words) [view diff] exact match in snippet view article find links to article

histrionicotoxin on end-plate potential have shown that the compound hinders membrane potential propagation, but has emergent characteristics with membrane hyperpolarizations

CHRFAM7A (785 words) [view diff] exact match in snippet view article find links to article

synaptic transmission synaptic transmission, cholinergic regulation of membrane potential nervous system process response to hypoxia cognition cellular calcium

HTR3A (964 words) [view diff] exact match in snippet view article find links to article

transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO

Kir6.2 (1,090 words) [view diff] exact match in snippet view article find links to article

regulation of insulin secretion response to testosterone regulation of membrane potential cellular response to tumor necrosis factor regulation of ion transmembrane

SLC26A6 (804 words) [view diff] exact match in snippet view article find links to article

fluid transport angiotensin-activated signaling pathway regulation of membrane potential regulation of intracellular pH cellular response to fructose stimulus

Depolarization (disambiguation) (85 words) [view diff] exact match in snippet view article

to: Depolarization, a decrease in the absolute value of a cell's membrane potential Depolarizer, a substance used to depolarize an electrochemical cell

Nav1.8 (3,611 words) [view diff] exact match in snippet view article find links to article

Slaughter RS, Garcia ML, Köhler MG (February 2006). "A high-capacity membrane potential FRET-based assay for NaV1.8 channels". Assay and Drug Development

Dicycloplatin (992 words) [view diff] case mismatch in snippet view article find links to article

properties of Hep G2 cells are observed: the declination of Mitochondria Membrane Potential, the release of cytochrome c from mitochondria to cytosol, the activation

Nitrendipine (672 words) [view diff] exact match in snippet view article find links to article

calcium channels in smooth muscle cells because of its lower resting membrane potential. The nitrendipine diffuses into the membrane and binds to its high

Bioelectricity (18,126 words) [view diff] exact match in snippet view article find links to article

(2014). "Single cell wound generates electric current circuit and cell membrane potential variations that requires calcium influx". Integr. Biol. 6 (7): 662–72

Forasartan (938 words) [view diff] exact match in snippet view article find links to article

during the plateau component, increasing the intracellular calcium and membrane potential which sustain depolarization and contraction. Forasartan is a competitive

Dofetilide (1,280 words) [view diff] exact match in snippet view article find links to article

upstroke of phase 0 depolarization), conduction velocity, or the resting membrane potential. There is a dose-dependent increase in the QT interval and the corrected

VDAC1 (4,089 words) [view diff] exact match in snippet view article find links to article

in increased mitochondrial permeability, disrupted mitochondrial membrane potential, elevated ROS production, cell death, and neuronal degeneration. VDAC1

Mitophagy (2,662 words) [view diff] exact match in snippet view article find links to article

mitochondria, the inner mitochondrial membrane becomes depolarized. This membrane potential is necessary for the TIM-mediated protein import. In depolarized mitochondria

Spermidine (1,241 words) [view diff] exact match in snippet view article find links to article

biological processes, (such as Ca2+, Na+, K+ -ATPase) thus maintaining membrane potential and controlling intracellular pH and volume. Spermidine regulates

ASIC1 (1,327 words) [view diff] exact match in snippet view article find links to article

sodium ion transmembrane transport sodium ion transport regulation of membrane potential cation transport memory sensory perception of sour taste ion transport

Crotoxin (2,224 words) [view diff] exact match in snippet view article find links to article

with many processes, including vesicle fusion and the mitochondrial membrane potential. Both these processes are important for acetylcholine homeostasis

Tedisamil (827 words) [view diff] exact match in snippet view article find links to article

the potassium channels are responsible for restoring the resting membrane potential during an action potential, lengthening their inactivation will stop

CHRNG (680 words) [view diff] exact match in snippet view article find links to article

postsynaptic membrane potential excitatory postsynaptic potential ion transmembrane transport chemical synaptic transmission regulation of membrane potential nervous

Glycine receptor (1,468 words) [view diff] exact match in snippet view article find links to article

as it happens in mature adults. The efflux of chloride causes the membrane potential to become more positive, or depolarized. As the cells mature, the

Reuptake (1,876 words) [view diff] exact match in snippet view article find links to article

leading to transmembrane charge movement that is enhanced by the membrane potential. These forces pull the neurotransmitter substrate into the cell, even

Calcium channel, voltage-dependent, T type, alpha 1H subunit (1,255 words) [view diff] exact match in snippet view article find links to article

heart contraction aldosterone biosynthetic process regulation of membrane potential regulation of ion transmembrane transport muscle organ development

HCN4 (1,304 words) [view diff] exact match in snippet view article find links to article

sodium ion transport SA node cell action potential regulation of membrane potential regulation of ion transmembrane transport cation transport ion transport

Mitochondrial fusion (2,367 words) [view diff] exact match in snippet view article find links to article

defects such as poor cell growth, heterogeneity of mitochondrial membrane potential and decreased cellular respiration. Mitochondrial fusion plays an

HCN1 (1,380 words) [view diff] exact match in snippet view article find links to article

protein localization ion transport sodium ion transport regulation of membrane potential sodium ion transmembrane transport potassium ion transmembrane transport

Phenoptosis (1,406 words) [view diff] exact match in snippet view article find links to article

mitochondria produce reactive oxygen species ROS, leading to loss of membrane potential within the mitochondria and death of the cell. Amoeba Dictyostelium

Antillatoxin (1,439 words) [view diff] exact match in snippet view article find links to article

exact mechanism is still unclear, as antillatoxin’s effect on the membrane potential is not sufficient to relieve the NMDA receptor block by magnesium

Digoxin (5,661 words) [view diff] exact match in snippet view article find links to article

increases in the sinoatrial and AV nodes. A less negative resting membrane potential is made, leading to increased irritability. The conduction velocity

Chloride anion exchanger (1,135 words) [view diff] exact match in snippet view article find links to article

elevation membrane hyperpolarization sulfate transport regulation of membrane potential regulation of intracellular pH ion transport anion transport bicarbonate

Dendritic spine (5,314 words) [view diff] exact match in snippet view article find links to article

representation, spine head voltage is the local spatial average of membrane potential in adjacent spines. The formulation maintains the feature that there

DiI (969 words) [view diff] no match in snippet view article find links to article

with tails much shorter than 12C, usually less than 7C are used as membrane-potential sensors for mitochondria, based on their vertical sinking into or

BNIP3 (2,667 words) [view diff] exact match in snippet view article find links to article

BNIP3 is necessary for clearing dysfunctional mitochondria with low membrane potential and reducing the build up of ROS to promote cell survival. BNIP3L

GABRB2 (6,283 words) [view diff] exact match in snippet view article find links to article

transmembrane transport regulation of membrane potential nervous system process regulation of postsynaptic membrane potential inhibitory synapse assembly Sources:Amigo

Vasodilation (2,204 words) [view diff] exact match in snippet view article find links to article

Hyperpolarization-mediated (Calcium channel blocker) Changes in the resting membrane potential of the cell affects the level of intracellular calcium through modulation

GalP (protein) (1,807 words) [view diff] exact match in snippet view article

protons are charged molecules, their import or export could disrupt the membrane potential of the cell (14). However, simultaneous import and export of protons

Delta atracotoxin (2,265 words) [view diff] exact match in snippet view article find links to article

spontaneous repetitive firing, but does not depolarize the resting membrane potential. Effects on the autonomic nervous system, including vomiting, profuse

Procainamide (2,072 words) [view diff] exact match in snippet view article find links to article

refractory period. This results in a disturbance in the artificial membrane potential and leads to a supraventricular tachycardia which induces failure

KCNK9 (1,545 words) [view diff] exact match in snippet view article find links to article

Biological process potassium ion transport ion transport stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO

NMDA receptor (11,603 words) [view diff] exact match in snippet view article find links to article

However, the NMDA receptor cation channel is blocked by Mg2+ at resting membrane potential. Magnesium unblock is not instantaneous, to unblock all available

Bcl-2-like protein 1 (2,219 words) [view diff] exact match in snippet view article find links to article

(voltage-dependent anion channels (VDACs) opening. VDACs regulate mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release

Rottlerin (1,583 words) [view diff] exact match in snippet view article find links to article

at high doses and results in depolarization of the mitochondrial membrane potential. It was found to reduce ATP levels, activate 5'-AMP-activated protein

CHRNA4 (1,160 words) [view diff] exact match in snippet view article find links to article

potential response to hypoxia cognition locomotory behavior regulation of membrane potential response to nicotine membrane depolarization nervous system process

Dendrotoxin (1,612 words) [view diff] exact match in snippet view article find links to article

the excitability of nerves and muscles by controlling the resting membrane potential and by repolarizing the membrane during action potentials. Dendrotoxin

Hibiscus (3,784 words) [view diff] exact match in snippet view article find links to article

sequential voltage calcium channels open. In response to the change in membrane potential voltage, gated potassium and chlorine channels open causing an efflux

AMPA receptor (6,711 words) [view diff] exact match in snippet view article find links to article

molecules called polyamines. Thus, when the neuron is at a depolarized membrane potential, polyamines will block the AMPAR channel more strongly, preventing

Batrachotoxin (2,096 words) [view diff] exact match in snippet view article find links to article

Voltage-sensitive sodium channels become persistently active at the resting membrane potential. Batrachotoxin kills by permanently blocking nerve signal transmission

Shimon Schuldiner (874 words) [view diff] exact match in snippet view article find links to article

brain disorders. Schuldiner, S., Rottenberg, H., and Avron, M. (1972) Membrane potential as a driving force for ATP synthesis in chloroplasts. FEBS Lett. 28

HBx (1,557 words) [view diff] exact match in snippet view article find links to article

localize to the mitochondria where HBx decreases the mitochondrial membrane potential and causes increased release of ROS. In addition, other HBV proteins

Chrysophanol (1,417 words) [view diff] exact match in snippet view article find links to article

oxidative phosphorylation which can result in decreased mitochondrial membrane potential, as well as an increase in abundance of reactive oxygen species, and

Purine nucleotide cycle (450 words) [view diff] exact match in snippet view article find links to article

activation of HIF-1α allows cardiomyocytes to sustain mitochondrial membrane potential during anoxic stress by utilizing fumarate produced by adenylosuccinate

Lethal injection (10,280 words) [view diff] exact match in snippet view article find links to article

than −70mV however as there is a raised resting membrane potential this negative membrane potential cannot be reached and the inactivation of the sodium

Silent synapse (1,613 words) [view diff] exact match in snippet view article find links to article

channel, at a place within the electrical field generated by the membrane potential. Normally, current will not flow through the NMDAR channel, even when

General anaesthetic (2,631 words) [view diff] exact match in snippet view article find links to article

modulate the potassium conductance that contributes to the resting membrane potential in neurons. Opening of these channels therefore facilitates a hyperpolarizing

TRPC3 (1,216 words) [view diff] exact match in snippet view article find links to article

maintaining a tonic inward depolarizing current that regulates resting membrane potential and promotes regular neuronal firing. Conversely, inhibiting TRPC3

Pituitary adenylate cyclase-activating peptide (1,628 words) [view diff] exact match in snippet view article find links to article

chemokine (C-C motif) ligand 5 production regulation of postsynaptic membrane potential positive regulation of cell population proliferation negative regulation

Polycystin 2 (1,068 words) [view diff] exact match in snippet view article find links to article

morphogenesis determination of left/right symmetry regulation of postsynaptic membrane potential negative regulation of ryanodine-sensitive calcium-release channel

PRDX3 (1,191 words) [view diff] exact match in snippet view article find links to article

process response to oxidative stress regulation of mitochondrial membrane potential cellular response to reactive oxygen species response to lipopolysaccharide

KCNH1 (1,566 words) [view diff] exact match in snippet view article find links to article

potassium ion transmembrane transport myoblast fusion regulation of membrane potential phosphatidylinositol-mediated signaling startle response ion transmembrane

Ankyrin-3 (1,654 words) [view diff] exact match in snippet view article find links to article

sodium ion transmembrane transporter activity positive regulation of membrane potential plasma membrane organization signal transduction Golgi to plasma membrane

Calcium signaling (2,148 words) [view diff] exact match in snippet view article find links to article

vascular diameters. The second is a rapid time dependent change in the membrane potential which leads to a very quick and uniform increase of Ca2+. This can

Phospholamban (980 words) [view diff] exact match in snippet view article find links to article

pathway involved in heart process regulation of cardiac muscle cell membrane potential regulation of the force of heart contraction by cardiac conduction

Potassium spatial buffering (2,050 words) [view diff] exact match in snippet view article find links to article

space impacts a variety of neuronal processes, such as maintenance of membrane potential, activation and inactivation of voltage gated channels, synaptic transmission

IRGs (2,805 words) [view diff] exact match in snippet view article find links to article

such as autophagy, mitochondrial fission, change in mitochondrial membrane potential and cell death. Human IRGM like its mouse counterpart, has been shown

Latrotoxin (2,266 words) [view diff] exact match in snippet view article find links to article

but also for water. This causes nerve terminal swelling. Further membrane potential disturbances occur due to permeability of small molecules, such as

Myogenic mechanism (1,080 words) [view diff] exact match in snippet view article find links to article

and close (e.g. If channels in cardiac pacemaker cells). When the membrane potential reaches depolarization threshold an action potential (AP) is fired

Local field potential (1,197 words) [view diff] exact match in snippet view article find links to article

filtering properties. Ionic diffusion, which plays an important role in membrane potential variations, can also act as a low-pass filter. Peyrache, A; Dehghani

POPDC3 (417 words) [view diff] exact match in snippet view article find links to article

membrane sarcolemma Biological process biological process regulation of membrane potential heart development skeletal muscle tissue development striated muscle

AKT2 (1,535 words) [view diff] exact match in snippet view article find links to article

cell population proliferation positive regulation of mitochondrial membrane potential negative regulation of apoptotic process carbohydrate metabolic process

Nav1.9 (2,164 words) [view diff] exact match in snippet view article find links to article

transmembrane transport sodium ion transport regulation of postsynaptic membrane potential regulation of sensory perception of pain transport Sources:Amigo /

UCL Neuroscience (1,583 words) [view diff] exact match in snippet view article find links to article

described a statistical analysis of fluctuations they observed in the membrane potential at the frog neuromuscular junction, which were induced by acetylcholine

Pleiotrophin (1,643 words) [view diff] exact match in snippet view article find links to article

to vitamin D learning response to activity negative regulation of membrane potential cerebellum development nervous system development positive regulation

HEBP2 (403 words) [view diff] exact match in snippet view article find links to article

granule lumen Biological process negative regulation of mitochondrial membrane potential positive regulation of necrotic cell death regulation of response

MFN1 (646 words) [view diff] case mismatch in snippet view article find links to article

"Mitochondrial Fusion in Human Cells Is Efficient, Requires the Inner Membrane Potential, and Is Mediated by Mitofusins". Mol. Biol. Cell. 13 (12): 4343–54

T-type calcium channel (2,776 words) [view diff] exact match in snippet view article find links to article

the voltage sensor of the channel opening or closing based on the membrane potential. The exact method by which the S4 segment controls the opening and

Valinomycin (826 words) [view diff] exact match in snippet view article find links to article

Veksler V, Zharkovsky A, Kaasik A (2006). "Loss of mitochondrial membrane potential is associated with increase in mitochondrial volume: physiological

Prestin (1,905 words) [view diff] exact match in snippet view article find links to article

positive regulation of cell motility sulfate transport regulation of membrane potential response to thyroid hormone regulation of intracellular pH chloride

Uncoupling protein (1,604 words) [view diff] exact match in snippet view article find links to article

PMID 11709080. Nicholls DG, Ward MW (April 2000). "Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts".

Vadimezan (603 words) [view diff] exact match in snippet view article find links to article

(STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential". The Journal of Biological Chemistry. 287 (47): 39776–88. doi:10

Dihydrolipoamide dehydrogenase (2,335 words) [view diff] exact match in snippet view article find links to article

mitochondrial acetyl-CoA biosynthetic process from pyruvate regulation of membrane potential aging branched-chain amino acid catabolic process tricarboxylic acid

Lipid emulsion (1,496 words) [view diff] exact match in snippet view article find links to article

matrix into the cytosol. The hydrogen flux disrupts the mitochondrial membrane potential and results in mitochondrial swelling, outer membrane rupture, and

Sib RNA (732 words) [view diff] exact match in snippet view article find links to article

mechanism of ibs protein is not fully understood, but a change in membrane potential upon over-expression of the protein suggests that interactions with

Ussing chamber (559 words) [view diff] exact match in snippet view article find links to article

The basis of membrane potential

WNT1-inducible-signaling pathway protein 3 (625 words) [view diff] exact match in snippet view article find links to article

regulation of signaling receptor activity regulation of mitochondrial membrane potential regulation of reactive oxygen species biosynthetic process Sources:Amigo

Tomatine (2,053 words) [view diff] exact match in snippet view article find links to article

disrupted membrane has an influence on sodium transport, by altering the membrane potential and reducing active sodium transport. When tomatine is orally ingested

BH3 interacting-domain death agonist (1,246 words) [view diff] exact match in snippet view article find links to article

regulation of apoptotic process positive regulation of mitochondrial membrane potential mitochondrial ATP synthesis coupled electron transport negative regulation

Carl Petersen (neuroscientist) (260 words) [view diff] exact match in snippet view article

University. Petersen, Carl (2017). "Whole-cell recording of neuronal membrane potential during behavior". Neuron. 95 (6): 1266–1281. doi:10.1016/j.neuron

Nav1.1 (2,613 words) [view diff] exact match in snippet view article find links to article

action potential propagation neuronal action potential regulation of membrane potential neuromuscular process controlling posture detection of mechanical

Jonathan Ashmore (1,069 words) [view diff] exact match in snippet view article find links to article

S2CID 1950263. Ashmore, J. F.; Meech, R. W. (1986). "Ionic basis of membrane potential in outer hair cells of guinea pig cochlea". Nature. 322 (6077): 368–371

POPDC2 (511 words) [view diff] exact match in snippet view article find links to article

process heart development skeletal muscle tissue development regulation of membrane potential striated muscle cell differentiation Sources:Amigo / QuickGO

Rhodamine 123 (247 words) [view diff] exact match in snippet view article find links to article

Its luminescence quantum yield is 0.90. L. B. Chen. "Mitochondrial membrane potential in living cells."Annu Rev Cell Biol. 4 (1988) 155–181 Darzynkiewicz

HERG (2,551 words) [view diff] exact match in snippet view article find links to article

potential cardiac muscle contraction signal transduction regulation of membrane potential regulation of ion transmembrane transport ventricular cardiac muscle

Isopimaric acid (416 words) [view diff] exact match in snippet view article find links to article

leads to an increased K+-efflux which hyperpolarizes the resting membrane potential, reducing the excitability of the cell in which the BK-channel is

Judith Graham Pool (850 words) [view diff] exact match in snippet view article find links to article

was widely respected in the field of hematology. - Measurements of membrane potential in a single muscle fiber (with Dr. Ralph W. Gerard), 1942 - The coagulation

Nystatin (2,188 words) [view diff] exact match in snippet view article find links to article

serum levels of nystatin are achieved. Nystatin also impacts cell membrane potential and transport by lipid peroxidation. Conjugated double bonds in nystatin's

Hypothalamus (4,695 words) [view diff] exact match in snippet view article find links to article

influence gene expression in particular neurons or induce changes in cell membrane potential and kinase activation, leading to diverse non-genomic cellular functions

Caveolin 3 (2,507 words) [view diff] exact match in snippet view article find links to article

depolarization during cardiac muscle cell action potential regulation of membrane potential muscle organ development regulation of calcium ion import plasma membrane

Osteoclast (2,810 words) [view diff] exact match in snippet view article find links to article

mineral. This includes ruffled border Cl− permeability to control membrane potential and basolateral Cl−/HCO3− exchange to maintain cytosolic pH in physiologically

GRID2 (2,147 words) [view diff] exact match in snippet view article find links to article

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential Cellular component integral component of membrane postsynaptic membrane

STOML2 (710 words) [view diff] exact match in snippet view article find links to article

cardiolipin metabolic process positive regulation of mitochondrial membrane potential T cell receptor signaling pathway interleukin-2 production mitochondrial

GABA transporter type 1 (2,154 words) [view diff] exact match in snippet view article find links to article

offset the positive charge of the Na+ in order to maintain the proper membrane potential. Occluded-out. Once fully loaded, this conformation prevents the release

ABCB5 (1,848 words) [view diff] exact match in snippet view article find links to article

component of plasma membrane membrane Biological process regulation of membrane potential cell differentiation compound eye corneal lens development transmembrane

Aldosterone (3,263 words) [view diff] exact match in snippet view article find links to article

zona glomerulosa cells within adrenal slices spontaneously generate membrane potential oscillations of low periodicity; this innate electrical excitability

Sulfate transporter (2,846 words) [view diff] exact match in snippet view article find links to article

microvillus membrane Biological process ossification regulation of membrane potential regulation of intracellular pH chloride transmembrane transport ion

Metabotropic glutamate receptor (3,645 words) [view diff] exact match in snippet view article find links to article

presynaptic inhibition, and do not appear to affect postsynaptic membrane potential by themselves. Receptors in groups II and III reduce the activity

Palladium (5,943 words) [view diff] exact match in snippet view article find links to article

appear to have a key role in palladium toxicity via mitochondrial membrane potential collapse and depletion of the cellular glutathione (GSH) level. Until

Alpha-actinin-2 (2,571 words) [view diff] exact match in snippet view article find links to article

signaling pathway cardiac muscle cell development regulation of membrane potential platelet degranulation actin filament uncapping MAPK cascade focal

RNF122 (440 words) [view diff] exact match in snippet view article find links to article

polyubiquitination protein ubiquitination negative regulation of mitochondrial membrane potential positive regulation of apoptotic process protein autoubiquitination

Strychnine (4,410 words) [view diff] exact match in snippet view article find links to article

ions into the neuron, causing a hyperpolarization which pushes the membrane potential further from threshold. Strychnine is an antagonist of glycine; it

Circumventricular organs (4,343 words) [view diff] exact match in snippet view article find links to article

it is worthy to note the VOLT neurons typically feature a resting membrane potential in the range of -50 to -67 mV with input resistances ranging from

TCL1A (939 words) [view diff] exact match in snippet view article find links to article

cell population proliferation positive regulation of mitochondrial membrane potential positive regulation of protein oligomerization positive regulation

Glutamate (neurotransmitter) (2,177 words) [view diff] exact match in snippet view article

depolarizing shift in epileptic attacks. This change in the resting membrane potential at seizure foci could cause spontaneous opening of voltage-activated

RIMS2 (828 words) [view diff] exact match in snippet view article find links to article

cAMP-mediated signaling calcium-ion regulated exocytosis regulation of membrane potential calcium ion-regulated exocytosis of neurotransmitter regulation of

FGF14 (876 words) [view diff] exact match in snippet view article find links to article

growth factor receptor signaling pathway regulation of postsynaptic membrane potential signal transduction nervous system development regulation of synaptic

Hepatitis B virus (5,203 words) [view diff] exact match in snippet view article find links to article

of HBx to the mitochondria where HBx decreases the mitochondrial membrane potential. In addition, another HBV protein, HBsAg, also increases ROS through

Coenzyme Q – cytochrome c reductase (2,221 words) [view diff] exact match in snippet view article find links to article

species reacting with oxygen to form superoxide. The effect of high membrane potential is thought to have a similar effect. Superoxide produced at the Qo

Nav1.5 (2,983 words) [view diff] exact match in snippet view article find links to article

determines whether the channel is opened or closed. At the resting membrane potential (around -85 mV), NaV1.5 channels are closed. Upon a stimulus (through

TUSC2 (568 words) [view diff] exact match in snippet view article find links to article

component mitochondrion Biological process regulation of mitochondrial membrane potential cell-cell signaling cell cycle chemokine (C-C motif) ligand 5 production

Quantitative models of the action potential (3,114 words) [view diff] exact match in snippet view article find links to article

PMID 14946714. Hodgkin AL, Huxley AF (1952). "The dual effect of membrane potential on sodium conductance in the giant axon of Loligo". J Physiol. 116

Neural encoding of sound (2,660 words) [view diff] exact match in snippet view article find links to article

particularly potassium, through the open MET channels causes the membrane potential of the hair cell to depolarize. This depolarization opens voltage-gated

Verrucotoxin (601 words) [view diff] exact match in snippet view article find links to article

reversible prolonged action potential duration with zero change in resting membrane potential from ventricular myocytes in guinea pigs. The second method verrucotoxin

Apamin (1,988 words) [view diff] exact match in snippet view article find links to article

ions out of the cell along their concentration gradient causes the membrane potential to become more negative. The SK channels are present in a wide range

Microfluorimetry (1,123 words) [view diff] exact match in snippet view article find links to article

of neurotoxins on both calcium ion concentration and mitochondrial membrane potential in individual cells. Microfluorimetry can also be used as a method

Salt and cardiovascular disease (3,210 words) [view diff] exact match in snippet view article find links to article

in the blood, extracellular and intracellular fluids, and resting membrane potential. The well known effect of sodium on blood pressure can be explained

PANK2 (gene) (806 words) [view diff] exact match in snippet view article

phosphorylation coenzyme A biosynthetic process regulation of mitochondrial membrane potential aerobic respiration regulation of triglyceride metabolic process regulation

Sodium–potassium pump (3,509 words) [view diff] exact match in snippet view article find links to article

activity and lower force production. In order to maintain the cell membrane potential, cells keep a low concentration of sodium ions and high levels of

STOX1 (114 words) [view diff] exact match in snippet view article find links to article

protein kinase activity cell division regulation of mitochondrial membrane potential positive regulation of gene expression positive regulation of cell

Respiratory complex I (6,480 words) [view diff] exact match in snippet view article find links to article

succinate-supported NAD+ reduction by ubiquinol – in the presence of a high membrane potential, but the exact catalytic mechanism remains unknown. Driving force