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searching for MSH6 19 found (47 total)

alternate case: mSH6

Mouse model of colorectal and intestinal cancer (2,488 words) [view diff] case mismatch in snippet view article find links to article

positioned nucleotides. Another gene involved in DNA mismatch repair is Msh6. Both the Msh6 and Msh2 mutant mice develop gastrointestinal cancer but the tumours
Sebaceous carcinoma (3,242 words) [view diff] exact match in snippet view article find links to article
MTS results from defects in DNA mismatch repair genes, MLH1, MSH2, and MSH6, leading to a buildup of unstable microsatellite sequences and replication
Temozolomide (3,090 words) [view diff] exact match in snippet view article find links to article
cytoreduction of tumors with TMZ and then selection or induction of mutant MSH6, MSH2, MLH1, or PMS2 proteins and cells which are MMRd and TMZ resistant
Somatic hypermutation (2,336 words) [view diff] exact match in snippet view article find links to article
L.; Hanaoka, F.; Yasui, A.; Woodgate, R.; Gearhart, P.J. (2005). "MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody
Carcinoma (3,137 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936
Cell damage (2,649 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–2408. doi:10.1093/carcin/bgl079. PMC 2612936
Neoplasm (5,760 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936
Microsatellite instability (2,676 words) [view diff] exact match in snippet view article find links to article
pathologies in patients with colon cancer. Furthermore, MMR proteins MLH 1, MSH 2, MSH6, and PMS2 are instrumental in periocular sebaceous carcinoma, which is seen
Glioma (5,598 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936
Genome instability (4,532 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936
Histone (9,235 words) [view diff] exact match in snippet view article find links to article
of H3 lysine 36 (H3K36me3) H3K36me3 has the ability to recruit the MSH2-MSH6 (hMutSα) complex of the DNA mismatch repair pathway. Consistently, regions
Human genome (10,963 words) [view diff] exact match in snippet view article find links to article
1:3500 APC Lynch syndrome 5–10% of all cases of bowel cancer MLH1, MSH2, MSH6, PMS2 Fanconi anemia 1:130000 births FANCC Neurological conditions Huntington
Synthetic lethality (2,718 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936
DNA repair (13,624 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–08. doi:10.1093/carcin/bgl079. PMC 2612936
Cancer epigenetics (11,937 words) [view diff] exact match in snippet view article find links to article
miR-101), DNA-PK (miR-101), ATR (miR-185), Wip1 (miR-16), MLH1, MSH2 and MSH6 (miR-155), ERCC3 and ERCC4 (miR-192) and UNG2 (mir-16, miR-34c and miR-199a)
Carcinogenesis (13,139 words) [view diff] case mismatch in snippet view article find links to article
in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6". Carcinogenesis. 27 (12): 2402–8. doi:10.1093/carcin/bgl079. PMC 2612936
Stress granule (12,979 words) [view diff] exact match in snippet view article find links to article
Protein 2 MOV10 MOV-10 Mov10 RISC Complex RNA Helicase yes MSH6 MSH6 DNA mismatch repair protein Msh6 MSI1 Musashi-1 Musashi RNA Binding Protein 1 yes MSI2
POLD1 (8,503 words) [view diff] exact match in snippet view article find links to article
germline mutations in DNA repair proteins involved in MMR (MSH2, MLH1, MSH6, and PMS2) have been described in Lynch syndrome (LS), which is characterized
Shapiro–Senapathy algorithm (8,791 words) [view diff] exact match in snippet view article find links to article
CAGGTATGC CAGGCATGC Intervening sequence, RNA processing,No amino acid change MSH6 Intron 9 TTTTTAATTTTAAGG TTTTTAATTTTGAGG Intervening sequence, RNA processing